Tag: drug


Found 100 sources
Source Match ReputationScore*

IUPHAR/BPS Guide to PHARMACOLOGY


The information in the database is presented at two levels: the initial view or landing pages for each target family provide expert-curated overviews of the key properties and selective ligands and tool compounds available. For selected targets more ...
100%

ChEMBL


ChEMBL is a manually curated database of bioactive molecules with drug-like properties. It brings together chemical, bioactivity and genomic data to aid the translation of genomic information into effective new drugs.
98%

Comparative Toxicogenomics Database


Database that aims to advance understanding about how environmental exposures affect human health. It provides manually curated information about chemical–gene/protein interactions, chemical–disease and gene–disease relationships. These data are inte ...
91%

ClinicalTrials.gov


ClinicalTrials.gov is a Web-based resource that provides patients, their family members, health care professionals, researchers, and the public with easy access to information on publicly and privately supported clinical studies on a wide range of di ...
91%

DrugBank


The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target information.
85%

Pharmacogenomics Knowledge Base


PharmGKB is a resource that provides information about how human genetic variation affects response to medications. PharmGKB collects, curates and disseminates knowledge about clinically actionable gene-drug associations and genotype-phenotype relati ...
71%

Virus Pathogen Database and Analysis Resource


The Virus Pathogen Database and Analysis Resource (ViPR) is an integrated repository of data and analysis tools for multiple virus families, supported by the National Institute of Allergy and Infectious Diseases (NIAID) Bioinformatics Resource Center ...
70%

Information system for G protein-coupled receptors (GPCRs)


The GPCRDB is a molecular-class information system that collects, combines, validates and stores large amounts of heterogenous data on G protein-coupled receptors (GPCRs). The GPCRDB contains data on sequences, ligand binding constants and mutations. ...
65%

Antimicrobial Peptide Database


The data stored in the APD are gleaned from the Protein Data Bank (PDB), Swiss-Prot Protein Knowledgebase and PubMed National Library of Medicine. The antimicrobial peptides in this database contain less than 100 amino acid residues, are in the matur ...
64%

Comprehensive Antibiotic Resistance Database


A bioinformatic database of antimicrobial resistance genes, their products and associated phenotypes.
64%

TTD, Therapeutic Target Database


The Therapeutic Target Database provides information about therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. Also included in this database are links ...
62%

RxNORM


RxNorm provides normalized names for clinical drugs and links its names to many of the drug vocabularies commonly used in pharmacy management and drug interaction software, including those of First Databank, Micromedex, MediSpan, Gold Standard Drug D ...
62%

SuperTarget


Drug-related information: medical indications, adverse drug effects, drug metabolism and Gene Ontology terms of the target proteins.
61%

BindingDB database of measured binding affinities


BindingDB enables research by making a growing collection of high-quality, quantitative, protein-ligand binding data findable and usable. Funded by NIGMS/NIH.
61%

Side Effect Resource


SIDER contains information on marketed medicines and their recorded adverse drug reactions. The information is extracted from public documents and package inserts. The available information include side effect frequency, drug and side effect classifi ...
60%

Orphanet


Orphanet is gathering knowledge on orphaned drugs and rare diseases (with genes involved). Data available via http://www.orphadata.org/
59%

ArachnoServer: Spider toxin database


ArachnoServer is a manually curated database containing information on the sequence, three-dimensional structure, and biological activity of protein toxins derived from spider venom.
57%

Chemical Effects in Biological Systems (CEBS)


CEBS (Chemical Effects in Biological Systems) is an integrated public repository for toxicogenomics data, including the study design and timeline, clinical chemistry and histopathology findings and microarray and proteomics data. CEBS contains data d ...
57%

Collection of Anti Microbial Petides R3


CAMPR3 (Collection of Anti-Microbial Peptides) has been generated to enhance research into AMP families. The collection is compatible with well-known databases such as PubMed and Uniprot with information like sequence, protein definition, accession n ...
56%

The Chemical Probes Portal


The Chemical Probes Portal is an online open access catalog of annotated small molecule inhibitors, agonists and other chemical tools for biological research and preclinical drug discovery. Annotations for are extensive and distinguish between activi ...
56%

The UC Irvine ChemDB


ChemDB is a chemical database containing nearly 5M commercially available small molecules, important for use as synthetic building blocks, probes in systems biology and as leads for the discovery of drugs and other useful compounds.
54%

Open Toxicogenomics Project-Genomics Assisted Toxicity Evaluation system


Open TG-GATEs is a public toxicogenomics database developed so that a wider community of researchers could utilize the fruits of TGP and TGP2 research. This database provides public access to data on 170 of the compounds catalogued in TG-GATEs. Data ...
54%

GeneWeaver


The GeneWeaver data and analytics website is a publically available resource for storing, curating and analyzing sets of genes from heterogeneous data sources. The system enables discovery of relationships among genes, variants, traits, drugs, enviro ...
54%

Toxin and Toxin Target Database


Toxin and Toxin Target Database (T3DB) is a bioinformatics resource that combines detailed toxin data with comprehensive toxin target information.
53%

Pancreatic Expression database


The Pancreatic Expression Database (PED) is a repository for pancreatic-derived -omics data. With a generic web-based system, the database provides the research community with an open access tool to mine currently available pancreatic cancer experime ...
53%

Bactibase: database dedicated to bacteriocins


BACTIBASE contains calculated or predicted physicochemical properties of bacteriocins produced by both Gram-positive and Gram-negative bacteria. The information in this database is very easy to extract and allows rapid prediction of relationships str ...
52%

Pathway Ontology


The goal of the Pathway Ontology is to cover all types of biological pathways, including altered and disease pathways, and to capture the relationships between them within the hierarchical structure of a Directed Acyclic Graph (DAG). The five nodes o ...
49%

SureChEMBL


SureChEMBL is a publicly available large-scale resource containing compounds extracted from the full text, images and attachments of patent documents. The data are extracted from the patent literature according to an automated text and image-mining p ...
49%

CDISC Laboratory Data Model


LAB provides a standard model for the acquisition and exchange of laboratory data, primarily between labs and sponsors or CROs. The LAB standard was specifically designed for the interchange of lab data acquired in clinical trials.
49%

The Drug Ontology


An ontology of drug products and packaged drug products.
48%

Herb Ingredient Targets


Herbal active Ingredients and their Targets
48%

Anatomical Therapeutic Chemical Classification


The Anatomical Therapeutic Chemical (ATC) Classification System is used for the classification of active ingredients of drugs according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties. It is con ...
48%

NIDA Data Share


The NIDA Data Share web site is an electronic environment that allows data from completed clinical trials to be distributed to investigators and the public in order to promote new research, encourage further analyses, and disseminate information to t ...
48%

PathBank


PathBank is an interactive, visual database containing more than 100 000 machine-readable pathways found in model organisms such as humans, mice, E. coli, yeast, and Arabidopsis thaliana. The majority of these pathways are not found in any other path ...
47%

Suggested Ontology for PHARMacogenomics


SO-Pharm is a formal ontology that represent domain knowledge in pharmacogenomics. To achieve this goal, SO-Pharm articulates ontologies from sub domains of phamacogenomics (i.e. genotype, phenotype, drug, trial representations). SO-Pharm enables to ...
47%

Coronavirus Infectious Disease Ontology


The Ontology of Coronavirus Infectious Disease (CIDO) is a community-driven open-source biomedical ontology in the area of coronavirus infectious disease. The CIDO is developed to provide standardized human- and computer-interpretable annotation and ...
47%

Enzyme Portal


The Enzyme Portal is for those interested in the biology of enzymes and proteins with enzymatic activity. It integrates publicly available information about enzymes, such as small-molecule chemistry, biochemical pathways and drug compounds. It contai ...
47%

Ontology for Systems Chemical Biology and Chemogenomics


Chem2Bio2RDF has been created by aggregating data from multiple chemogenomics repositories and is cross-linked into Bio2RDF and LODD. There is also a linked-path generation tool to facilitate SPARQL query generation, and have created extended SPARQL ...
47%

DrugCentral


DrugCentral is online drug information that provides information on active ingredients, chemical entities, pharmaceutical products, drug mode of action, indications, and pharmacologic mode of action. DrugCentral monitors FDA, EMA, and PMDA for new dr ...
47%

PROMISCUOUS


Protein-protein and drug-protein interactions for studies of drug repositioning
46%

Clinical Knowledgebase


The Jackson Laboratory Clinical Knowledgebase (CKB) is a semi-automated/manually curated database of gene/variant annotations, therapy knowledge, diagnostic/prognostic information, and clinical trials related to oncology. CKB not only contains curren ...
46%

Patients-Derived tumor Xenograft Finder


PDX Finder is an open repository for the upload and storage of clinical, genomic and functional Patient-Derived Xenograph (PDX) data which provides a comprehensive global catalogue of PDX models available for researchers across distributed repository ...
45%

WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs


WITHDRAWN is a database of withdrawn and discontinued drugs that were recalled from global markets due to safety concerns. The database serves as a useful resource with information about the therapeutic (or primary) targets, off-targets, toxicity typ ...
45%

AVPdb


Antiviral peptides (AVPs) have exhibited huge potential in inhibiting viruses by targeting various stages of their life cycle. Therefore, we have developed AVPdb, available online at http://crdd.osdd.net/servers/avpdb, to provide a dedicated resource ...
45%

Common Evidence Model


The CommonEvidenceModel (CEM) provides an evidence base of a wide variety of sources with information relevant for assessing associations between drugs and health outcomes of interest.
45%

Ontology of Adverse Events


The Ontology of Adverse Events (OAE) is a community-driven ontology that is developed to standardize and integrate data on biomedical adverse events (e.g., vaccine and drug adverse events) and support computer-assisted reasoning. As a result of a med ...
45%

National Addiction & HIV Data Archive Program (NAHDAP)


NAHDAP acquires, preserves and disseminates data relevant to drug addiction and HIV research. The scope of the data housed at NAHDAP covers a wide range of legal and illicit drugs (alcohol, tobacco, marijuana, cocaine, synthetic drugs, and others) an ...
45%

Physician Data Query


Physician Data Query (PDQ) Terminology is part of NCI's comprehensive cancer information database, which contains expert summaries on a wide range of cancer topics, a listing of some 30,000 cancer clinical trials from around the world, a directory of ...
45%

AHTPdb


Antihypertensive peptides database
44%

Veterans Health Administration National Drug File


Veterans Health Administration National Drug File is a centrally maintained electronic drug list used by the VHA hospitals and clinics. Facilities use the NDF to check drug interactions, to manage orders, and to send outpatient prescriptions to regio ...
42%

Exposome-Explorer


Biomarkers of exposure to disease risk factors
42%

Drug2Gene


Drug2Gene is a free multi-species drug-target knowledge base. It contains integrated and unified data of publicly available relations between drugs/compounds and their gene/protein targets gathered from 20 publicly available bio- and chemoinformatics ...
42%

BioDrugScreen


A resource for computational drug design and discovery
42%

Adverse Drug Reaction Markup Language


The Adverse Drug Reaction Markup Language (EU-ADR ML) was created to as part of the EU-ADR project. The ultimate aim of this project was to develop an innovative approach to the early detection of adverse drug reactions. The status of this format is ...
41%

Read Codes Clinical Terms Version 3


Read Codes are a coded thesaurus of clinical terms. They have been used in the NHS since 1985. There are two versions: version 2 (v2) and version 3 (CTV3 or v3). Both versions provide a standard vocabulary for clinicians to record patient findings an ...
40%

National Drug Data File


The National Drug Data File vocabulary supports clinical research and patient care. Please note that we have been unable to confirm the current status of NDDF and its relationship with FDB MedKnowledge. Until that time, the FAIRsharing team has marke ...
39%

Functional Therapeutic Chemical Classification System


The Functional Therapeutic Chemical Classification System (FTC) defines over 20,000 mechanisms and modes of action for approved drugs. The resource abstracts away from the traditional chemical structure-based approach and focuses solely on the mode o ...
39%

Master Drug Data Base Clinical Drugs


Master Drug Data Base provides comprehensive and current drug information from a single source. The resource provides pricing and descriptive drug information on name brand, generic, prescription and OTC medications, and herbal products. It includes ...
39%

Translational Medicine Ontology


This project focuses on the development of a high level patient-centric ontology for the pharmaceutical industry. The ontology should enable silos in discovery research, hypothesis management, experimental studies, compounds, formulation, drug develo ...
39%

Minimal information for Chemosensitivity Assays


Minimal information for Chemosensitivity Assays (MICHA) is both a web tool to aid annotation of drug sensitivity screens and a guideline for defining the minimal information required to: capture critical drug sensitivity assay components, allow the F ...
37%

Drug Database for Inborn Errors of Metabolism Ontology


DDIEM Ontology for the Drug Database for Inborn Errors of Metabolism. The DDIEM database is a database of therapeutic strategies and treatments for inborn errors of metabolism. These strategies are classified by mechanism and outcome using the DDIEM ...
35%

Health Canada Drug Product Database


The Health Canada Drug Product Database contains product specific information on drugs approved for use in Canada. The database is managed by Health Canada and includes human pharmaceutical and biological drugs, veterinary drugs and disinfectant prod ...
35%

SwissBioisostere


A database of molecular replacements for ligand design
35%

Parasite Experiment Ontology


The Parasite Experiment Ontology (PEO) models the processes, instruments, parameters, and sample details that will be used to annotate experimental results with “provenance” metadata (derivation history of results). The ontology was created to enable ...
35%

Pharmacovigilance Ontology


The pharmacovigilance ontology connects known facts on drugs, disease, ADEs, and their molecular mechanisms.
35%

Orphadata


Orphadata provides the scientific community with comprehensive, quality datasets related to rare diseases and orphan drugs from the Orphanet knowledge base, in reusable formats.
35%

NutriChem


Nutritional and medicinal value of plant-based foods
35%

iPPI-DB


Inhibitors of protein-protein interactions
35%

Monarch Initiative


Human disease-related phenotypes in model organisms
35%

SuperDrug


The database contains approximately 2500 3D-structures of active ingredients of essential marketed drugs. For selection purposes and for correlation of structural similarity with medical application, the assignment of the Anatomical Therapeutic Chemi ...
33%

HIV Drug Resistance Database


The HIV Drug Resistance Database is a compilation of mutations in HIV genes that confer resistance to anti-HIV drugs. Currently, 673 mutations to RT, Protease, Env, Gag, Integrase, FIV RT and SIV RT are stored. The database may be searched by gene, c ...
33%

DART - Drug Adverse Reaction Targets


A database for facilitating the search for drug adverse reaction target. It contains information about known drug adverse rection targets, functions and properties. Associated references are also included.
33%

ADReCS


Adverse Drug Reaction Classification System
33%

Pharos


Heterogenous data on unstudied and understudied drug targets
33%

GDSC


Genomics of Drug Sensitivity in Cancer: Sensitivity for anti-cancer drugs in various cell lines
33%

sc-PDB


Potential drug-binding sites in protein structures from the PDB
33%

GLIDA


G-protein coupled receptors (GPCRs) represent one of the most important families of drug targets in pharmaceutical development. GLIDA is a novel public GPCR-related chemical genomic database that is primarily focused on the correlation of information ...
33%

VARIDT


The Variability of Drug Transporter Database (VARIDT) is constructed to provide the comprehensive data of all aspects of drug transporter variability. Based on the comprehensive review on all FDA approved and >2,000 clinical trial drugs, VARIDT confi ...
33%

SuperPain


33%

StreptomeDB


33%

VIOLIN


Vaccine Investigation and Online Information Network
33%

G4LDB


G-quadruplex Ligands Database
33%

SuperNatural


Natural compounds and their suppliers
33%

MEGaRes


Mechanisms of antimicrobial resistance
33%

SATPdb


A database of structurally annotated peptides
33%

CPPsite


Experimentally validated Cell Penetrating Peptides
33%

EHFPI


Essential Host Factors for Pathogenic Infection
33%

INTEDE


The Interactome of Drug-Metabolizing Enzymes (INTEDE) is a database designed to systematically provide the data of all types of drug-metabolizing enzyme (DME) interaction. INTEDE confirmed 1,047 unique DMEs (448 host and 599 microbial), for the first ...
33%

NPACT


Naturally occuring Plant based Anticancerous Compound Targets
33%

BioLiP


Biologically relevant ligand-protein interactions
33%

BioMuta and BioExpress


33%

Transformer


Biotransformation of xenobioitics - drugs and food ingredients - by human enzymes
33%

Antimicrobial Combination Networks


The database aims to bridge the gap between agent repositories and studies documenting the effect of antimicrobial combination therapies. Most notably, our primary aim is to compile data on the combination of antimicrobial agents, namely natural prod ...
33%

RepoDB


Drug repositioning, the process of discovering, validating, and marketing previously approved drugs for new indications, is of growing interest to academia and industry due to reduced time and costs associated with repositioned drugs. Computational m ...
33%

Wiki-Pi


Wiki-Pi is a wiki resource centered on human protein-protein interactions. Wiki-Pi's intuitive search functionality allows you to retrieve and discover interactions effectively.
33%

Peptaibol


The Peptaibol Database is a sequence and structure resource for the unusual class of peptides known as peptaibols. The database includes sequence, biological source, and bibliographical data for the naturally-occurring peptaibols. Information is also ...
33%

Defensins Knowledgebase


The defensins knowledgebase is a manually curated database and information source devoted to the defensin family of antimicrobial peptides. The current version of the database holds a comprehensive collection of over 350 defensin records each contain ...
33%

GIMICA


The Host Genetic and Immune Factors Shaping Human Microbiota (GIMICA) is a database systematically providing host genetic factors (HGFs) and host immune factors (HIFs). Both factors are essential for defining the chemical and physical landscapes inha ...
33%

BacMet


Antibiotic resistance has become a major human health concern due to widespread use, misuse and overuse of antibiotics. In addition to antibiotics, antibacterial biocides and metals can contribute to the development and maintenance of antibiotic resi ...
33%

DBAASP


The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an open-access, comprehensive database containing information on amino acid sequences, chemical modifications, 3D structures, bioactivities and toxicities of peptides that p ...
33%

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