TDR Targets
Names
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TDR Targets
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
TDRtargets
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
tdr_targets
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
Names
More detailed information about this field from each metasource.
TDR Targets
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
TDRtargets
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
tdr_targets
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
Other names: TDRtargets, tdr_targets
Names
More detailed information about this field from each metasource.
TDR Targets
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
TDRtargets
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
tdr_targets
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
TDR Targets integrates chemical and genomic information and allows users to prioritize targets and compounds to develop and repurpose new drugs and chemical tools for human pathogens. The TDR Target Project was started in 2005 after a call for applications was launched by TDR (Special Programme for Research and Training in Tropical Diseases). As a result, the TDR Targets Database was established to help develop a portfolio of candidate drug targets for 5 major human pathogens. This then became a resource for prioritizing targets for neglected tropical diseases. TDR Targets is led and run by the Trypanosomatics group at IIB-UNSAM (Argentina, https://trypanosomatics.org) with help with external collaborators worldwide.
Description
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TDR Targets integrates chemical and genomic information and allows users to prioritize targets and compounds to develop and repurpose new drugs and chemical tools for human pathogens. The TDR Target Project was started in 2005 after a call for applications was launched by TDR (Special Programme for Research and Training in Tropical Diseases). As a result, the TDR Targets Database was established to help develop a portfolio of candidate drug targets for 5 major human pathogens. This then became a resource for prioritizing targets for neglected tropical diseases. TDR Targets is led and run by the Trypanosomatics group at IIB-UNSAM (Argentina, https://trypanosomatics.org) with help with external collaborators worldwide.
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
TDR Targets integrates chemical and genomic information and allows users to prioritize targets and compounds to develop and repurpose new drugs and chemical tools for human pathogens. The TDR Target Project was started in 2005 after a call for applications was launched by TDR (Special Programme for Research and Training in Tropical Diseases (UNICEF / UNDP / World Bank / WHO, http://www.who.int/tdr)). As a result, the TDR Targets Database was established to help develop a portfolio of candidate drug targets for 5 major human pathogens. This shortly turned into a resource for prioritizing targets for neglected tropical diseases. TDR Targets is led and run by the Trypanosomatics group at IIB-UNSAM (Argentina, https://trypanosomatics.org) with help with external collaborators worldwide.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Tropical Disease Research (TDR) Database: Designed and developed to facilitate the rapid identification and prioritization of molecular targets for drug development, focusing on pathogens responsible for neglected human diseases. The database integrates pathogen specific genomic information with functional data for genes collected from various sources, including literature curation. Information can be browsed and queried.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
Webpage:
https://tdrtargets.orgWebpage
More detailed information about this field from each metasource.
https://tdrtargets.org
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://tdrtargets.org/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
Licence:
Name: TDR Targets Data Access PolicyLicence name
More detailed information about this field from each metasource.
TDR Targets Data Access Policy
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Licence URL
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https://tdrtargets.org/about
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
Genomic-scale prioritization of drug targets: the TDR Targets database
PMID: 18927591
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
PMID: 20808766
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
TDR Targets: a chemogenomics resource for neglected diseases
PMID: 22116064
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
http://dx.doi.org/10.1093/nar/gkz999
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
Genomic-scale prioritization of drug targets: the TDR Targets database
PMID: 18927591
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
PMID: 20808766
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
TDR Targets: a chemogenomics resource for neglected diseases
PMID: 22116064
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
http://dx.doi.org/10.1093/nar/gkz999
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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Genomic-scale prioritization of drug targets: the TDR Targets database
PubMed citations: 125.
125 articles citing: Genomic-scale prioritization of drug targets: the TDR Targets database
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production. PMID:35025955
Genome-Based Drug Target Identification in Human Pathogen Streptococcus gallolyticus. PMID:33841489
De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation. PMID:33767335
Genomics, Computational Biology and Drug Discovery for Mycobacterial Infections: Fighting the Emergence of Resistance. PMID:33101362
Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major. PMID:33044977
Excretory/Secretory Metabolome of the Zoonotic Roundworm Parasite Toxocara canis. PMID:32781793
A systematic strategy for the investigation of vaccines and drugs targeting bacteria. PMID:32637049
Repositioning Salirasib as a new antimalarial agent. PMID:31803400
TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration. PMID:31680154
Structure-based Druggability Assessment of Anti-virulence Targets from Pseudomonas aeruginosa. PMID:31038064
Brazilian malaria molecular targets (BraMMT): selected receptors for virtual high-throughput screening experiments. PMID:30810604
Identification of potential drug targets and inhibitor of the pathogenic bacteria Shigella flexneri 2a through the subtractive genomic approach. PMID:30607324
Rv1288, a Two Domain, Cell Wall Anchored, Nutrient Stress Inducible Carboxyl-Esterase of Mycobacterium tuberculosis, Modulates Cell Wall Lipid. PMID:30560095
Interactive online application for the prediction, ranking and prioritisation of drug targets in Schistosoma haematobium. PMID:30482220
CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. PMID:30345257
Identification of novel drug targets in bovine respiratory disease: an essential step in applying biotechnologic techniques to develop more effective therapeutic treatments. PMID:29765203
Using Yeast Synthetic Lethality To Inform Drug Combination for Malaria. PMID:29358287
An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae. PMID:29049350
The Trypomastigote Small Surface Antigen from Trypanosoma cruzi Improves Treatment Evaluation and Diagnosis in Pediatric Chagas Disease. PMID:28978686
Structures of Medicago truncatula L-Histidinol Dehydrogenase Show Rearrangements Required for NAD+ Binding and the Cofactor Positioned to Accept a Hydride. PMID:28874718
Decoding the similarities and differences among mycobacterial species. PMID:28854187
Drug discovery and development for rare genetic disorders. PMID:28731526
A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major. PMID:28638238
Bioinformatics in translational drug discovery. PMID:28487472
Data Intensive Genome Level Analysis for Identifying Novel, Non-Toxic Drug Targets for Multi Drug Resistant Mycobacterium tuberculosis. PMID:28425478
Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps. PMID:28325368
Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB. PMID:28275291
Successful application of virtual screening and molecular dynamics simulations against antimalarial molecular targets. PMID:27982302
Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1. PMID:27932461
Integrated analysis of the Plasmodium species transcriptome. PMID:27322479
Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis. PMID:26856535
Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities. PMID:26738801
A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases. PMID:26735851
The drug target genes show higher evolutionary conservation than non-target genes. PMID:26716901
Computer-Aided Design of Orally Bioavailable Pyrrolidine Carboxamide Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Pharmacokinetic Profiles. PMID:26703572
Distinctive Behaviors of Druggable Proteins in Cellular Networks. PMID:26699810
Identification of potential drug targets by subtractive genome analysis of Escherichia coli O157:H7: an in silico approach. PMID:26677339
To Hit or Not to Hit, That Is the Question - Genome-wide Structure-Based Druggability Predictions for Pseudomonas aeruginosa Proteins. PMID:26360059
A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case. PMID:26100720
A Novel Trypanosoma cruzi Protein Associated to the Flagellar Pocket of Replicative Stages and Involved in Parasite Growth. PMID:26086767
Novel Drug Targets for Food-Borne Pathogen Campylobacter jejuni: An Integrated Subtractive Genomics and Comparative Metabolic Pathway Study. PMID:26061459
GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway. PMID:26043892
Application of RNAi to Genomic Drug Target Validation in Schistosomes. PMID:25992548
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures. PMID:25961325
Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. PMID:25945710
Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets. PMID:25574133
Proteome scale comparative modeling for conserved drug and vaccine targets identification in Corynebacterium pseudotuberculosis. PMID:25573232
In silico repositioning-chemogenomics strategy identifies new drugs with potential activity against multiple life stages of Schistosoma mansoni. PMID:25569258
In silico work flow for scaffold hopping in Leishmania. PMID:25399834
Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase. PMID:25284249
Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment. PMID:25278579
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium. PMID:25278220
Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection. PMID:25220818
Elucidating the structural basis of diphenyl ether derivatives as highly potent enoyl-ACP reductase inhibitors through molecular dynamics simulations and 3D-QSAR study. PMID:24935113
TuberQ: a Mycobacterium tuberculosis protein druggability database. PMID:24816183
Network Medicine: New Paradigm in the -Omics Era. PMID:24634802
Selecting targets from eukaryotic parasites for structural genomics and drug discovery. PMID:24590708
Genetic validation of aminoacyl-tRNA synthetases as drug targets in Trypanosoma brucei. PMID:24562907
In silico prediction of antimalarial drug target candidates. PMID:24533280
Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it? PMID:24533267
Using genetic findings in autism for the development of new pharmaceutical compounds. PMID:24292384
ModBase, a database of annotated comparative protein structure models and associated resources. PMID:24271400
DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements. PMID:24243843
Prediction of the P. falciparum target space relevant to malaria drug discovery. PMID:24146604
Antiparasitic chemotherapy: from genomes to mechanisms. PMID:24050701
The open access malaria box: a drug discovery catalyst for neglected diseases. PMID:23798988
TiPs: a database of therapeutic targets in pathogens and associated tools. PMID:23698860
Inhibition of isoleucyl-tRNA synthetase as a potential treatment for human African Trypanosomiasis. PMID:23548908
Discovery-2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria. PMID:23537208
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. PMID:23384594
Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholerae targeted by Piper betel derived compounds. PMID:23382822
Objective assessment of cancer genes for drug discovery. PMID:23274470
A genomic scale map of genetic diversity in Trypanosoma cruzi. PMID:23270511
Withdrawn. PMID:23167715
Investigating mammalian tyrosine phosphatase inhibitors as potential 'piggyback' leads to target Trypanosoma brucei transmission. PMID:23066974
Stoking the drug target pipeline for human African trypanosomiasis. PMID:22925123
Comparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidates. PMID:22912793
In vivo-validated essential genes identified in Acinetobacter baumannii by using human ascites overlap poorly with essential genes detected on laboratory media. PMID:22911967
Strategic protein target analysis for developing drugs to stop dental caries. PMID:22899687
Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease. PMID:22540944
Chemistry and biology of multicomponent reactions. PMID:22435608
Effect of the explicit flexibility of the InhA enzyme from Mycobacterium tuberculosis in molecular docking simulations. PMID:22369213
FReDoWS: a method to automate molecular docking simulations with explicit receptor flexibility and snapshots selection. PMID:22369186
Integrated dataset of screening hits against multiple neglected disease pathogens. PMID:22247786
TDR Targets: a chemogenomics resource for neglected diseases. PMID:22116064
Glucose-6-phosphate dehydrogenase of trypanosomatids: characterization, target validation, and drug discovery. PMID:22091394
Schistosoma comparative genomics: integrating genome structure, parasite biology and anthelmintic discovery. PMID:22024648
DDTRP: Database of Drug Targets for Resistant Pathogens. PMID:21938213
Target repurposing for neglected diseases. PMID:21859304
Specific and nonhomologous isofunctional enzymes of the genetic information processing pathways as potential therapeutical targets for tritryps. PMID:21808726
HelmCoP: an online resource for helminth functional genomics and drug and vaccine targets prioritization. PMID:21760913
The Strategies WDK: a graphical search interface and web development kit for functional genomics databases. PMID:21705364
Structures, targets and recent approaches in anti-leishmanial drug discovery and development. PMID:21629509
Targeting protein-protein interactions for parasite control. PMID:21556146
Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni. PMID:21548963
Natural products as starting points for future anti-malarial therapies: going back to our roots? PMID:21411014
Rapid analysis of pharmacology for infectious diseases. PMID:21401504
A systems biological view of intracellular pathogens. PMID:21349090
NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children. PMID:21317536
Structure-based systems biology for analyzing off-target binding. PMID:21292475
Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery. PMID:21129975
The Mycobacterium tuberculosis drugome and its polypharmacological implications. PMID:21079673
RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening. PMID:20976050
Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds. PMID:20813141
Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. PMID:20808766
Targeted Therapy Database (TTD): a model to match patient's molecular profile with current knowledge on cancer biology. PMID:20706624
Open source tool for prediction of genome wide protein-protein interaction network based on ortholog information. PMID:20684769
Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90. PMID:20559560
Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation. PMID:20470405
Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes. PMID:20361874
Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy. PMID:20334617
Eating at the table of another: metabolomics of host-parasite interactions. PMID:20159614
The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase. PMID:20070944
Newly identified antibacterial compounds are topoisomerase poisons in African trypanosomes. PMID:20008775
Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi. PMID:19943957
Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. PMID:19933331
New medicines to improve control and contribute to the eradication of malaria. PMID:19834482
Advancing drug innovation for neglected diseases-criteria for lead progression. PMID:19707561
Discovery: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria. PMID:19642978
The Mycobacterium tuberculosis cytochrome P450 system. PMID:19635450
LeishCyc: a biochemical pathways database for Leishmania major. PMID:19497128
A kernel for open source drug discovery in tropical diseases. PMID:19381286
A kernel for the Tropical Disease Initiative. PMID:19352362
ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr. PMID:19194660
TcSNP: a database of genetic variation in Trypanosoma cruzi. PMID:18974180 -
Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
PubMed citations: 62.
62 articles citing: Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
The Use of AlphaFold for In Silico Exploration of Drug Targets in the Parasite Trypanosoma cruzi. PMID:35909956
Pathogenomic in silico approach identifies NSP-A and Fe-IIISBP as possible drug targets in Neisseria Meningitidis MC58 and development of pharmacophores as novel therapeutic candidates. PMID:35879631
Deletion of Glutamine Synthetase Gene Disrupts the Survivability and Infectivity of Leishmania donovani. PMID:33732662
Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi. PMID:33021977
Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus. PMID:32523532
In vitro effectivity of three approved drugs and their synergistic interaction against Leishmania infantum. PMID:32463611
Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogens. PMID:32106219
The Novel Serine/Threonine Protein Kinase LmjF.22.0810 from Leishmania major may be Involved in the Resistance to Drugs such as Paromomycin. PMID:31718000
TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration. PMID:31680154
Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics. PMID:31235822
Human Migration and the Spread of the Nematode Parasite Wuchereria bancrofti. PMID:31077328
In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets. PMID:30596650
Targeting the Pentose Phosphate Pathway: Characterization of a New 6PGL Inhibitor. PMID:30467026
CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. PMID:30345257
Transcriptome-wide analysis of the Trypanosoma cruzi proliferative cycle identifies the periodically expressed mRNAs and their multiple levels of control. PMID:29182646
An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae. PMID:29049350
A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major. PMID:28638238
Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps. PMID:28325368
Successful application of virtual screening and molecular dynamics simulations against antimalarial molecular targets. PMID:27982302
Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis. PMID:26856535
A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases. PMID:26735851
Identification of Immunodominant B-cell Epitope Regions of Reticulocyte Binding Proteins in Plasmodium vivax by Protein Microarray Based Immunoscreening. PMID:26323838
Application of RNAi to Genomic Drug Target Validation in Schistosomes. PMID:25992548
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures. PMID:25961325
In silico search of energy metabolism inhibitors for alternative leishmaniasis treatments. PMID:25918726
Functional analysis of Girardia tigrina transcriptome seeds pipeline for anthelmintic target discovery. PMID:25600302
Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets. PMID:25574133
Proteome scale comparative modeling for conserved drug and vaccine targets identification in Corynebacterium pseudotuberculosis. PMID:25573232
In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery. PMID:25561926
Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment. PMID:25278579
Expression profile of the Schistosoma japonicum degradome reveals differential protease expression patterns and potential anti-schistosomal intervention targets. PMID:25275570
Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection. PMID:25220818
In silico prediction of antimalarial drug target candidates. PMID:24533280
Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it? PMID:24533267
Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis. PMID:24489942
Computational models for neglected diseases: gaps and opportunities. PMID:23990313
Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni. PMID:23908765
In-silico Leishmania target selectivity of antiparasitic terpenoids. PMID:23823876
The open access malaria box: a drug discovery catalyst for neglected diseases. PMID:23798988
Current drug targets for helminthic diseases. PMID:23529336
Identification and characterization of potential therapeutic candidates in emerging human pathogen Mycobacterium abscessus: a novel hierarchical in silico approach. PMID:23527108
Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholerae targeted by Piper betel derived compounds. PMID:23382822
Functional mapping of protein kinase A reveals its importance in adult Schistosoma mansoni motor activity. PMID:23326613
A genomic scale map of genetic diversity in Trypanosoma cruzi. PMID:23270511
Improving N-terminal protein annotation of Plasmodium species based on signal peptide prediction of orthologous proteins. PMID:23153225
Drug Target Exploitable Structural Features of Adenylyl Cyclase Activity in Schistosoma mansoni. PMID:23133313
Comparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidates. PMID:22912793
In vivo-validated essential genes identified in Acinetobacter baumannii by using human ascites overlap poorly with essential genes detected on laboratory media. PMID:22911967
In-silico investigation of antitrypanosomal phytochemicals from Nigerian medicinal plants. PMID:22848767
Multiplex proteomics analysis of gender-associated proteins in Brugia malayi. PMID:22819962
Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum. PMID:22474358
Integrated dataset of screening hits against multiple neglected disease pathogens. PMID:22247786
A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, Brugia malayi. PMID:22180794
Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection. PMID:22091403
Glucose-6-phosphate dehydrogenase of trypanosomatids: characterization, target validation, and drug discovery. PMID:22091394
Schistosoma comparative genomics: integrating genome structure, parasite biology and anthelmintic discovery. PMID:22024648
Insights into the functional biology of schistosomes. PMID:22013990
Two-stage flux balance analysis of metabolic networks for drug target identification. PMID:21689470
A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implications. PMID:21408104
High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome. PMID:21363968
A systems biological view of intracellular pathogens. PMID:21349090
Analyses of an expressed sequence tag library from Taenia solium, Cysticerca. PMID:21200421 -
TDR Targets: a chemogenomics resource for neglected diseases
PubMed citations: 48.
48 articles citing: TDR Targets: a chemogenomics resource for neglected diseases
Characterization of Calcium-Dependent Protein Kinase 2A, a Potential Drug Target Against Cryptosporidiosis. PMID:35558125
From Genome to Drugs: New Approaches in Antimicrobial Discovery. PMID:34177572
Applications of artificial intelligence to drug design and discovery in the big data era: a comprehensive review. PMID:34110579
Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity. PMID:33689276
Chagas Disease: Perspectives on the Past and Present and Challenges in Drug Discovery. PMID:33238613
COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics. PMID:33166390
Genomics, Computational Biology and Drug Discovery for Mycobacterial Infections: Fighting the Emergence of Resistance. PMID:33101362
Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major. PMID:33044977
Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax. PMID:32601162
Deep phosphoproteome analysis of Schistosoma mansoni leads development of a kinomic array that highlights sex-biased differences in adult worm protein phosphorylation. PMID:32203512
Computational/in silico methods in drug target and lead prediction. PMID:31711157
TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration. PMID:31680154
MycoResistance: a curated resource of drug resistance molecules in Mycobacteria. PMID:31290951
Drug repurposing for antimicrobial discovery. PMID:30833727
Brazilian malaria molecular targets (BraMMT): selected receptors for virtual high-throughput screening experiments. PMID:30810604
Discovery and Genetic Validation of Chemotherapeutic Targets for Chagas' Disease. PMID:30666299
MDAD: A Special Resource for Microbe-Drug Associations. PMID:30581775
Interactive online application for the prediction, ranking and prioritisation of drug targets in Schistosoma haematobium. PMID:30482220
Chemoinformatics Strategies for Leishmaniasis Drug Discovery. PMID:30443215
Network-Based Methods for Prediction of Drug-Target Interactions. PMID:30356768
CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. PMID:30345257
Identification of Missing Carbon Fixation Enzymes as Potential Drug Targets in Mycobacterium Tuberculosis. PMID:30218604
Machine Learning for Drug-Target Interaction Prediction. PMID:30200333
TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species. PMID:29220433
Target-Pathogen: a structural bioinformatic approach to prioritize drug targets in pathogens. PMID:29106651
Target-similarity search using Plasmodium falciparum proteome identifies approved drugs with anti-malarial activity and their possible targets. PMID:29088219
Decoding the similarities and differences among mycobacterial species. PMID:28854187
Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps. PMID:28325368
In silico structural characterization of protein targets for drug development against Trypanosoma cruzi. PMID:27665464
Integrated analysis of the Plasmodium species transcriptome. PMID:27322479
A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases. PMID:26735851
A large-scale crop protection bioassay data set. PMID:26175909
Maximum flow approach to prioritize potential drug targets of Mycobacterium tuberculosis H37Rv from protein-protein interaction network. PMID:26061871
Application of RNAi to Genomic Drug Target Validation in Schistosomes. PMID:25992548
Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. PMID:25945716
In silico search of energy metabolism inhibitors for alternative leishmaniasis treatments. PMID:25918726
Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation. PMID:25799414
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium. PMID:25278220
Drug repurposing and human parasitic protozoan diseases. PMID:25057459
Genetic validation of aminoacyl-tRNA synthetases as drug targets in Trypanosoma brucei. PMID:24562907
In silico prediction of antimalarial drug target candidates. PMID:24533280
The ChEMBL bioactivity database: an update. PMID:24214965
Antiparasitic chemotherapy: from genomes to mechanisms. PMID:24050701
Computational models for neglected diseases: gaps and opportunities. PMID:23990313
Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholerae targeted by Piper betel derived compounds. PMID:23382822
Database resources for the tuberculosis community. PMID:23332401
A genomic scale map of genetic diversity in Trypanosoma cruzi. PMID:23270511
Stoking the drug target pipeline for human African trypanosomiasis. PMID:22925123 - http://dx.doi.org/10.1093/nar/gkz999
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More detailed information about this field from each metasource.
acceptor
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
annotation
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
antigen
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
bioactivity
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
chemical descriptor
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
chemical entity
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
computational predictions
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
dna sequence data
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
disease
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
donor
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
drug
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
enzyme commission number
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene ontology enrichment
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene expression data
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene name
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
genome annotation
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
glycosylphosphatidylinositol anchor
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
molecular structure
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
molecular weight
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
proton
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
sequence length
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
signal peptide
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
structure
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
logp
metasource: Fairsharing.org
version: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
genomics databases (non-vertebrate)
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
general genomics databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
model organisms
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
pathology
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
medicinal chemistry
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
drug discovery
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:34.850590
Tags
More detailed information about this field from each metasource.
acceptor
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
annotation
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
antigen
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
bioactivity
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
chemical descriptor
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
chemical entity
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
computational predictions
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
dna sequence data
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
disease
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
donor
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
drug
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
enzyme commission number
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene ontology enrichment
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene expression data
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene name
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
genome annotation
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
glycosylphosphatidylinositol anchor
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
molecular structure
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
molecular weight
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
proton
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
sequence length
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
signal peptide
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
structure
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
logp
metasource: Fairsharing.orgversion: FAIRsharing.org: TDR Targets; TDR Targets; DOI: https://doi.org/10.25504/FAIRsharing.6c4fvf; Last edited: Feb. 4, 2021, 2:47 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
genomics databases (non-vertebrate)
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
general genomics databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
small molecules
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
model organisms
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
pathology
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
medicinal chemistry
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
drug discovery
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:34.850590
acceptor antigen bioactivity chemical descriptor chemical entity computational predictions dna sequences disease donor drug enzyme commission number gene gene ontology enrichment gene expression gene name genome annotation glycosylphosphatidylinositol anchor molecular structure molecular weight proton sequence length signal peptide structure logp genomics general genomics small molecule model organisms pathology medicinal chemistry drug discovery
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