Herb Ingredient Targets

Names
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Herb Ingredient Targets
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

HIT
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

hit
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

Other names: HIT, hit

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Herbal active Ingredients and their Targets

Webpage:

http://lifecenter.sgst.cn/hit

Publications:

Publications
More detailed information about this field from each metasource.

HIT: linking herbal active ingredients to targets
PMID: 21097881
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

http://nar.oxfordjournals.org/content/39/suppl_1/D1055
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

HIT: linking herbal active ingredients to targets PubMed citations: 108.

108 articles citing: HIT: linking herbal active ingredients to targets

Network pharmacology analysis and molecular docking to unveil the potential mechanisms of San-Huang-Chai-Zhu formula treating cholestasis. PMID:35196362
Translational Informatics for Natural Products as Antidepressant Agents. PMID:35127696
HIT 2.0: an enhanced platform for Herbal Ingredients' Targets. PMID:34986599
Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti-inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway. PMID:34964259
In Silico Prediction and Bioactivity Evaluation of Chemical Ingredients Against Influenza A Virus From Isatis tinctoria L. PMID:34950027
Network-Based Identification and Experimental Validation of Drug Candidates Toward SARS-CoV-2 via Targeting Virus-Host Interactome. PMID:34539756
Identification of Potential Bioactive Ingredients and Mechanisms of the Guanxin Suhe Pill on Angina Pectoris by Integrating Network Pharmacology and Molecular Docking. PMID:34422068
Deciphering the Therapeutic Mechanisms of Wuzi Ershen Decoction in Treating Oligoasthenozoospermia through the Network Pharmacology Approach. PMID:34394386
Shiquan Yuzhen Decoction inhibits angiogenesis and tumor apoptosis caused by non-small cell lung cancer and promotes immune response. PMID:34377231
Anti-Autophagy Mechanism of Zhi Gan Prescription Based on Network Pharmacology in Nonalcoholic Steatohepatitis Rats. PMID:34349657
Siteng Fang Reverses Multidrug Resistance in Gastric Cancer: A Network Pharmacology and Molecular Docking Study. PMID:34026648
Network Pharmacology-Based Prediction of Mechanism of Shenzhuo Formula for Application to DKD. PMID:33968154
Network pharmacology-based study to explore the mechanism of the Yiqi Gubiao pill in lung cancer treatment. PMID:33692853
In silico identification of natural products from Traditional Chinese Medicine for cancer immunotherapy. PMID:33558586
Network Patterns of Herbal Combinations in Traditional Chinese Clinical Prescriptions. PMID:33551800
A Study on the Therapeutic Efficacy of San Zi Yang Qin Decoction for Non-Alcoholic Fatty Liver Disease and the Underlying Mechanism Based on Network Pharmacology. PMID:33505505
A network pharmacology perspective for deciphering potential mechanisms of action of Solanum nigrum L. in bladder cancer. PMID:33494738
Review on natural products databases: where to find data in 2020. PMID:33431011
COCONUT online: Collection of Open Natural Products database. PMID:33423696
HERB: a high-throughput experiment- and reference-guided database of traditional Chinese medicine. PMID:33264402
Systems pharmacology approach uncovers Ligustilide attenuates experimental colitis in mice by inhibiting PPARγ-mediated inflammation pathways. PMID:33130971
Literature based discovery of alternative TCM medicine for adverse reactions to depression drugs. PMID:33106157
Herbal pair Huangqin-Baishao: mechanisms underlying inflammatory bowel disease by combined system pharmacology and cell experiment approach. PMID:32988394
Systems pharmacology-based approach to investigate the mechanisms of Danggui-Shaoyao-san prescription for treatment of Alzheimer's disease. PMID:32948180
Uncovering the Mechanisms of Cryptotanshinone as a Therapeutic Agent Against Hepatocellular Carcinoma. PMID:32903546
Ingredients, Anti-Liver Cancer Effects and the Possible Mechanism of DWYG Formula Based on Network Prediction. PMID:32523357
Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare. PMID:32390855
ZiYinHuaTan Recipe Inhibits Cell Proliferation and Promotes Apoptosis in Gastric Cancer by Suppressing PI3K/AKT Pathway. PMID:32382534
Investigation of cardiovascular protective effect of Shenmai injection by network pharmacology and pharmacological evaluation. PMID:32293408
The potential drug for treatment in pancreatic adenocarcinoma: a bioinformatical study based on distinct drug databases. PMID:32206083
Network Pharmacology-Based Investigation of the System-Level Molecular Mechanisms of the Hematopoietic Activity of Samul-Tang, a Traditional Korean Herbal Formula. PMID:32104198
Comparative Network Pharmacology Analysis of Classical TCM Prescriptions for Chronic Liver Disease. PMID:31824313
Active Ingredients and Action Mechanisms of Yi Guan Jian Decoction in Chronic Hepatitis B Patients with Liver Fibrosis. PMID:31565062
In Silico Study of Anti-Insomnia Mechanism for Suanzaoren Prescription. PMID:31507421
An Insight Into the Molecular Mechanism of Berberine Towards Multiple Cancer Types Through Systems Pharmacology. PMID:31447670
The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology. PMID:31412658
NaPLeS: a natural products likeness scorer-web application and database. PMID:31399811
Systems Pharmacology for Investigation of the Mechanisms of Action of Traditional Chinese Medicine in Drug Discovery. PMID:31379563
Bioassay Directed Isolation, Biological Evaluation and in Silico Studies of New Isolates from Pteris cretica L. PMID:31331076
Identify the Key Active Ingredients and Pharmacological Mechanisms of Compound XiongShao Capsule in Treating Diabetic Peripheral Neuropathy by Network Pharmacology Approach. PMID:31210774
A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling. PMID:31178408
Untargeted Metabolomics Study of the In Vitro Anti-Hepatoma Effect of Saikosaponin d in Combination with NRP-1 Knockdown. PMID:30978940
Effects and possible mechanism of Ruyiping formula application to breast cancer based on network prediction. PMID:30918282
Network Pharmacology Analysis of Damnacanthus indicus C.F.Gaertn in Gene-Phenotype. PMID:30906409
Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network. PMID:30867892
Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment. PMID:30846939
NP-Scout: Machine Learning Approach for the Quantification and Visualization of the Natural Product-Likeness of Small Molecules. PMID:30682850
Protective Effect of Salidroside Against Diabetic Kidney Disease Through Inhibiting BIM-Mediated Apoptosis of Proximal Renal Tubular Cells in Rats. PMID:30564128
YaTCM: Yet another Traditional Chinese Medicine Database for Drug Discovery. PMID:30546860
Anti-Inflammatory Effect of a TCM Formula Li-Ru-Kang in Rats With Hyperplasia of Mammary Gland and the Underlying Biological Mechanisms. PMID:30524280
A Network Pharmacology Approach to Uncover the Molecular Mechanisms of Herbal Formula Ban-Xia-Xie-Xin-Tang. PMID:30410554
SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping. PMID:30380087
ETCM: an encyclopaedia of traditional Chinese medicine. PMID:30365030
Quantitative and systems pharmacology 4. Network-based analysis of drug pleiotropy on coronary artery disease. PMID:30359818
CMAUP: a database of collective molecular activities of useful plants. PMID:30357356
A New Strategy to Uncover the Anticancer Mechanism of Chinese Compound Formula by Integrating Systems Pharmacology and Bioinformatics. PMID:30108661
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study. PMID:30034946
Hepatoprotective Effect of San-Cao Granule on Con A-Induced Liver Injury in Mice and Mechanisms of Action Exploration. PMID:29946260
Heterogeneous network propagation for herb target identification. PMID:29589568
Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia. PMID:29551975
The Mechanisms of Bushen-Yizhi Formula as a Therapeutic Agent against Alzheimer's Disease. PMID:29449587
Integrated Modules Analysis to Explore the Molecular Mechanisms of Phlegm-Stasis Cementation Syndrome with Ischemic Heart Disease. PMID:29403392
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation. PMID:29330507
Analysis of the main active ingredients and bioactivities of essential oil from Osmanthus fragrans Var. thunbergii using a complex network approach. PMID:29282071
Naturally Available Extracts Inhibiting Cancer Progression: A Systematic Review. PMID:29279018
TCMID 2.0: a comprehensive resource for TCM. PMID:29106634
NPASS: natural product activity and species source database for natural product research, discovery and tool development. PMID:29106619
System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus. PMID:29051733
Quantitative and Systems Pharmacology. 1. In Silico Prediction of Drug-Target Interactions of Natural Products Enables New Targeted Cancer Therapy. PMID:28956927
Bitter or not? BitterPredict, a tool for predicting taste from chemical structure. PMID:28935887
Chinese Herbal Medicine Meets Biological Networks of Complex Diseases: A Computational Perspective. PMID:28690664
Synergistic effects of Chuanxiong-Chishao herb-pair on promoting angiogenesis at network pharmacological and pharmacodynamic levels. PMID:28551771
Systems Pharmacology-Based Discovery of Natural Products for Precision Oncology Through Targeting Cancer Mutated Genes. PMID:28294568
A network-based method for mechanistic investigation of Shexiang Baoxin Pill's treatment of cardiovascular diseases. PMID:28272527
Network pharmacology-based and clinically relevant prediction of the active ingredients and potential targets of Chinese herbs in metastatic breast cancer patients. PMID:28212580
Herb pair Danggui-Honghua: mechanisms underlying blood stasis syndrome by system pharmacology approach. PMID:28074863
Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. PMID:28031022
Systems pharmacology exploration of botanic drug pairs reveals the mechanism for treating different diseases. PMID:27841365
To Unveil the Molecular Mechanisms of Qi and Blood through Systems Biology-Based Investigation into Si-Jun-Zi-Tang and Si-Wu-Tang formulae. PMID:27677604
A corpus for plant-chemical relationships in the biomedical domain. PMID:27650402
Systems Pharmacology Dissection of the Integrated Treatment for Cardiovascular and Gastrointestinal Disorders by Traditional Chinese Medicine. PMID:27597117
Network pharmacology dissection of multiscale mechanisms of herbal medicines in stage IV gastric adenocarcinoma treatment. PMID:27583849
Molecular targets of Chinese herbs: a clinical study of hepatoma based on network pharmacology. PMID:27143508
Pathway Analysis Revealed Potential Diverse Health Impacts of Flavonoids that Bind Estrogen Receptors. PMID:27023590
HerDing: herb recommendation system to treat diseases using genes and chemicals. PMID:26980517
A network pharmacology approach to discover active compounds and action mechanisms of San-Cao Granule for treatment of liver fibrosis. PMID:26929602
BATMAN-TCM: a Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine. PMID:26879404
A Systems Biology-Based Investigation into the Pharmacological Mechanisms of Sheng-ma-bie-jia-tang Acting on Systemic Lupus Erythematosus by Multi-Level Data Integration. PMID:26560501
Paeonia lactiflora Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway. PMID:26366057
Phytochemica: a platform to explore phytochemicals of medicinal plants. PMID:26255307
SerpentinaDB: a database of plant-derived molecules of Rauvolfia serpentina. PMID:26238452
Review of natural product databases. PMID:26009974
Deciphering the therapeutic mechanisms of Xiao-Ke-An in treatment of type 2 diabetes in mice by a Fangjiomics approach. PMID:25960133
Natural products as leads in schistosome drug discovery. PMID:25625682
Effective chemical constituent's identification of extracting solution from herbs - a review. PMID:25371564
BioPhytMol: a drug discovery community resource on anti-mycobacterial phytomolecules and plant extracts. PMID:25360160
Target network differences between western drugs and Chinese herbal ingredients in treating cardiovascular disease. PMID:25104437
Systems pharmacology dissection of multi-scale mechanisms of action for herbal medicines in stroke treatment and prevention. PMID:25093322
TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. PMID:24735618
Constructing a knowledge-based database for dermatological integrative medical information. PMID:24386003
Bioinformatics analysis for the antirheumatic effects of huang-lian-jie-du-tang from a network perspective. PMID:24348693
Navigating traditional chinese medicine network pharmacology and computational tools. PMID:23983798
Network pharmacology: a new approach for chinese herbal medicine research. PMID:23762149
HIM-herbal ingredients in-vivo metabolism database. PMID:23721660
NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database. PMID:23203877
TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysis. PMID:23203875
Network-based drug discovery by integrating systems biology and computational technologies. PMID:22877768
Bioinformatics opportunities for identification and study of medicinal plants. PMID:22589384
http://nar.oxfordjournals.org/content/39/suppl_1/D1055

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other molecular biology databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

drugs and drug design
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

drug discovery
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

protein targeting and localisation
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

proteins
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

drug development
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:58.708643

molecular biology drug small molecule drug discovery protein targeting and localisation proteins drug development

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