DEMA: a distance-bounded energy-field minimization algorithm to model and layout biomolecular networks with quantitative features.
PMID:35758816
Contribution of Model Organisms to Investigating the Far-Reaching Consequences of PRPP Metabolism on Human Health and Well-Being.
PMID:35741038
Protein-Protein Interaction (PPI) Network of Zebrafish Oestrogen Receptors: A Bioinformatics Workflow.
PMID:35629318
Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease.
PMID:35395180
Integrating protein copy numbers with interaction networks to quantify stoichiometry in clathrin-mediated endocytosis.
PMID:35354856
Protein interaction networks provide insight into fetal origins of chronic obstructive pulmonary disease.
PMID:35331221
Correlation Imputation for Single-Cell RNA-seq.
PMID:35325552
Identifying large-scale interaction atlases using probabilistic graphs and external knowledge.
PMID:35321220
Protein Function Prediction Based on PPI Networks: Network Reconstruction vs Edge Enrichment.
PMID:34970299
The Hippo Signaling Pathway in Cancer: A Cell Cycle Perspective.
PMID:34944834
Convolutional neural network for human cancer types prediction by integrating protein interaction networks and omics data.
PMID:34667236
LncTx: A network-based method to repurpose drugs acting on the survival-related lncRNAs in lung cancer.
PMID:34377365
Correlation Imputation in Single cell RNA-seq using Auxiliary Information and Ensemble Learning.
PMID:34278382
Environmental robustness of the global yeast genetic interaction network.
PMID:33958448
The contributions from the progenitor genomes of the mesopolyploid Brassiceae are evolutionarily distinct but functionally compatible.
PMID:33863805
Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets.
PMID:33750515
Chemical-Genetic Interactions of Bacopa monnieri Constituents in Cells Deficient for the DNA Repair Endonuclease RAD1 Appear Linked to Vacuolar Disruption.
PMID:33668176
A large accessory protein interactome is rewired across environments.
PMID:32924934
Network-principled deep generative models for designing drug combinations as graph sets.
PMID:32657357
Predicting Self-Interacting Proteins Using a Recurrent Neural Network and Protein Evolutionary Information.
PMID:32550764
Systematic analysis of ovarian cancer platinum-resistance mechanisms via text mining.
PMID:32160916
The Need for SMN-Independent Treatments of Spinal Muscular Atrophy (SMA) to Complement SMN-Enhancing Drugs.
PMID:32117013
Systematic genetics and single-cell imaging reveal widespread morphological pleiotropy and cell-to-cell variability.
PMID:32064787
Genome-wide inference of the Camponotus floridanus protein-protein interaction network using homologous mapping and interacting domain profile pairs.
PMID:32047225
A comparative study of topology-based pathway enrichment analysis methods.
PMID:31684881
Speeding up the drug discovery process: structural similarity searches using molecular surfaces.
PMID:31440460
Membrane protein-regulated networks across human cancers.
PMID:31311925
Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol.
PMID:31034808
A Comprehensive Drosophila melanogaster Transcription Factor Interactome.
PMID:30995488
Analysis of Predicted Host-Parasite Interactomes Reveals Commonalities and Specificities Related to Parasitic Lifestyle and Tissues Tropism.
PMID:30815000
Molecular subtyping of cancer and nomination of kinase candidates for inhibition with phosphoproteomics: Reanalysis of CPTAC ovarian cancer.
PMID:30594550
A Network Pharmacology Approach to Uncover the Molecular Mechanisms of Herbal Formula Ban-Xia-Xie-Xin-Tang.
PMID:30410554
Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation.
PMID:30303482
Evidence that RNA Viruses Drove Adaptive Introgression between Neanderthals and Modern Humans.
PMID:30290142
MiRNA-BD: an evidence-based bioinformatics model and software tool for microRNA biomarker discovery.
PMID:30081733
Automatic extraction of protein-protein interactions using grammatical relationship graph.
PMID:30066644
Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology.
PMID:29932108
A systems immunology approach identifies the collective impact of 5 miRs in Th2 inflammation.
PMID:29875322
Systematic Evaluation of Molecular Networks for Discovery of Disease Genes.
PMID:29605183
Preferential retention of genes from one parental genome after polyploidy illustrates the nature and scope of the genomic conflicts induced by hybridization.
PMID:29590103
Key genes and regulatory networks involved in the initiation, progression and invasion of colorectal cancer.
PMID:29568567
A homologous mapping method for three-dimensional reconstruction of protein networks reveals disease-associated mutations.
PMID:29560828
Prediction of Disordered Regions and Their Roles in the Anti-Pathogenic and Immunomodulatory Functions of Butyrophilins.
PMID:29401697
Co-complex protein membership evaluation using Maximum Entropy on GO ontology and InterPro annotation.
PMID:29390084
Support vector machine classifier for prediction of the metastasis of colorectal cancer.
PMID:29328363
Protein-protein interaction analysis to identify biomarker networks for endometriosis.
PMID:29201163
SPRINT: ultrafast protein-protein interaction prediction of the entire human interactome.
PMID:29141584
CRISPR/Cas9-Based Engineering of the Epigenome.
PMID:28985525
High rate of adaptation of mammalian proteins that interact with Plasmodium and related parasites.
PMID:28957326
Genome wide host gene expression analysis in mice experimentally infected with Pasteurella multocida.
PMID:28704394
Application of a systems approach to study developmental gene regulation.
PMID:28510076
iTRAQ-based quantitative proteomic analysis of Yamanaka factors reprogrammed breast cancer cells.
PMID:28423718
RNA Seq analysis for transcriptome profiling in response to classical swine fever vaccination in indigenous and crossbred pigs.
PMID:28361233
Gene Expression, Protein Function and Pathways of Arabidopsis thaliana Responding to Silver Nanoparticles in Comparison to Silver Ions, Cold, Salt, Drought, and Heat.
PMID:28347022
Downstream targets of GWAS-detected genes for breast, lung, and prostate and colon cancer converge to G1/S transition pathway.
PMID:28334950
IODNE: An integrated optimization method for identifying the deregulated subnetwork for precision medicine in cancer.
PMID:28266149
Systematic analysis of molecular mechanisms for HCC metastasis via text mining approach.
PMID:28108733
Properties of human disease genes and the role of genes linked to Mendelian disorders in complex disease aetiology.
PMID:28053046
CanProVar 2.0: An Updated Database of Human Cancer Proteome Variation.
PMID:27977206
Personalized anticancer therapy selection using molecular landscape topology and thermodynamics.
PMID:27793055
Protein folding, binding, and droplet formation in cell-like conditions.
PMID:27771543
A computational interactome and functional annotation for the human proteome.
PMID:27770567
A global genetic interaction network maps a wiring diagram of cellular function.
PMID:27708008
Systems Medicine as an Emerging Tool for Cardiovascular Genetics.
PMID:27626034
Entropy-based divergent and convergent modular pattern reveals additive and synergistic anticerebral ischemia mechanisms.
PMID:27480252
Identification of key target genes and pathways in laryngeal carcinoma.
PMID:27446427
Mining Functional Modules in Heterogeneous Biological Networks Using Multiplex PageRank Approach.
PMID:27446133
Relational Network for Knowledge Discovery through Heterogeneous Biomedical and Clinical Features.
PMID:27427091
Network analysis and juvenile idiopathic arthritis (JIA): a new horizon for the understanding of disease pathogenesis and therapeutic target identification.
PMID:27411317
Quantitative Determination of Flexible Pharmacological Mechanisms Based On Topological Variation in Mice Anti-Ischemic Modular Networks.
PMID:27383195
BcCluster: A Bladder Cancer Database at the Molecular Level.
PMID:27376128
Endophenotype Network Models: Common Core of Complex Diseases.
PMID:27278246
Systematic analysis of the molecular mechanism underlying atherosclerosis using a text mining approach.
PMID:27251057
Viruses are a dominant driver of protein adaptation in mammals.
PMID:27187613
A Network of Splice Isoforms for the Mouse.
PMID:27079421
Dissecting dysfunctional crosstalk pathways regulated by miRNAs during glioma progression.
PMID:27013589
Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain.
PMID:26894958
Network-based in silico drug efficacy screening.
PMID:26831545
Identification of miRNA-mRNA regulatory modules by exploring collective group relationships.
PMID:26817421
CSGene: a literature-based database for cell senescence genes and its application to identify critical cell aging pathways and associated diseases.
PMID:26775705
BioGRID: A Resource for Studying Biological Interactions in Yeast.
PMID:26729913
Scope and limitations of yeast as a model organism for studying human tissue-specific pathways.
PMID:26714768
Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.
PMID:26694192
CancerNet: a database for decoding multilevel molecular interactions across diverse cancer types.
PMID:26690544
Properly defining the targets of a transcription factor significantly improves the computational identification of cooperative transcription factor pairs in yeast.
PMID:26679776
YAGM: a web tool for mining associated genes in yeast based on diverse biological associations.
PMID:26678566
PCTFPeval: a web tool for benchmarking newly developed algorithms for predicting cooperative transcription factor pairs in yeast.
PMID:26677932
A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans.
PMID:26676933
Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage.
PMID:26658111
NDEx, the Network Data Exchange.
PMID:26594663
Interpreting functional effects of coding variants: challenges in proteome-scale prediction, annotation and assessment.
PMID:26494363
Integrative analysis of human protein, function and disease networks.
PMID:26399914
Systematic Analysis of the Molecular Mechanism Underlying Decidualization Using a Text Mining Approach.
PMID:26222155
Genes Caught In Flagranti: Integrating Renal Transcriptional Profiles With Genotypes and Phenotypes.
PMID:26215861
The BioPlex Network: A Systematic Exploration of the Human Interactome.
PMID:26186194
Transcriptomic-Wide Discovery of Direct and Indirect HuR RNA Targets in Activated CD4+ T Cells.
PMID:26162078
A reproducible approach to high-throughput biological data acquisition and integration.
PMID:26157642
Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network.
PMID:25982363
FNTM: a server for predicting functional networks of tissues in mouse.
PMID:25940632
Follicle Online: an integrated database of follicle assembly, development and ovulation.
PMID:25931457
Lineage-specific sequence evolution and exon edge conservation partially explain the relationship between evolutionary rate and expression level in A. thaliana.
PMID:25930165
Predicted protein-protein interactions in the moss Physcomitrella patens: a new bioinformatic resource.
PMID:25885037
Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin.
PMID:25883214
A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome.
PMID:25853560
Recent positive selection has acted on genes encoding proteins with more interactions within the whole human interactome.
PMID:25840415
Genomic analysis of host - Peste des petits ruminants vaccine viral transcriptome uncovers transcription factors modulating immune regulatory pathways.
PMID:25827022
The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins.
PMID:25813344
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.
PMID:25803170
Module organization and variance in protein-protein interaction networks.
PMID:25797237
Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage.
PMID:25784190
LC-MS/MS-based serum proteomics for identification of candidate biomarkers for hepatocellular carcinoma.
PMID:25778709
The identification of specific methylation patterns across different cancers.
PMID:25774687
Expression profile of mitrogen-activated protein kinase (MAPK) signaling genes in the skeletal muscle & liver of rat with type 2 diabetes: role in disease pathology.
PMID:25758573
Efficient prediction of progesterone receptor interactome using a support vector machine model.
PMID:25741764
Network tuned multiple rank aggregation and applications to gene ranking.
PMID:25708095
An integrative approach for a network based meta-analysis of viral RNAi screens.
PMID:25691914
Reconstructing genome-wide protein-protein interaction networks using multiple strategies with homologous mapping.
PMID:25602759
The molecular genetic architecture of attention deficit hyperactivity disorder.
PMID:25600112
Protein interactome of muscle invasive bladder cancer.
PMID:25569276
Integrated systems analysis reveals a molecular network underlying autism spectrum disorders.
PMID:25549968
Network-based association of hypoxia-responsive genes with cardiovascular diseases.
PMID:25530704
Complex-based analysis of dysregulated cellular processes in cancer.
PMID:25521701
A comprehensive performance evaluation on the prediction results of existing cooperative transcription factors identification algorithms.
PMID:25521604
A proteomic analysis reveals that Snail regulates the expression of the nuclear orphan receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and interleukin 17 (IL-17) to inhibit adipocyte differentiation.
PMID:25505127
Pathway crosstalk analysis of microarray gene expression profile in human hepatocellular carcinoma.
PMID:25480734
Systems Medicine: from molecular features and models to the clinic in COPD.
PMID:25471042
In silico prediction of synthetic lethality by meta-analysis of genetic interactions, functions, and pathways in yeast and human cancer.
PMID:25452682
Tissue-aware data integration approach for the inference of pathway interactions in metazoan organisms.
PMID:25431329
Systematic identification of cell size regulators in budding yeast.
PMID:25411401
Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification--mass spectrometry data.
PMID:25300367
Identification of essential proteins based on ranking edge-weights in protein-protein interaction networks.
PMID:25268881
Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
PMID:25255318
Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.
PMID:25254076
Integration strategy is a key step in network-based analysis and dramatically affects network topological properties and inferring outcomes.
PMID:25243127
Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast.
PMID:25208583
Unbiased functional clustering of gene variants with a phenotypic-linkage network.
PMID:25166029
Bioinformatics analysis of biomarkers and transcriptional factor motifs in Down syndrome.
PMID:25118625
Modeling dynamic functional relationship networks and application to ex vivo human erythroid differentiation.
PMID:25115705
An integrative omics strategy to assess the germ cell secretome and to decipher sertoli-germ cell crosstalk in the Mammalian testis.
PMID:25111155
Prediction and functional analysis of the sweet orange protein-protein interaction network.
PMID:25091279
A dedicated database system for handling multi-level data in systems biology.
PMID:25053973
Large Scale Chemical Cross-linking Mass Spectrometry Perspectives.
PMID:25045217
Construction and analysis of microRNA-transcription factor regulation network in Arabidopsis.
PMID:25014374
The domain landscape of virus-host interactomes.
PMID:24991570
Building a hierarchical organization of protein complexes out of protein association data.
PMID:24978199
Correlating information contents of gene ontology terms to infer semantic similarity of gene products.
PMID:24963342
Scale-space measures for graph topology link protein network architecture to function.
PMID:24931989
Improving functional annotation for industrial microbes: a case study with Pichia pastoris.
PMID:24929579
Comparative analysis of human tissue interactomes reveals factors leading to tissue-specific manifestation of hereditary diseases.
PMID:24921629
Essential functional modules for pathogenic and defensive mechanisms in Candida albicans infections.
PMID:24757665
Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.
PMID:24708540
Tissue-specific expression and regulatory networks of pig microRNAome.
PMID:24699212
A second-generation protein-protein interaction network of Helicobacter pylori.
PMID:24627523
Modelling the yeast interactome.
PMID:24589662
Protein-protein interactions prediction based on iterative clique extension with gene ontology filtering.
PMID:24578640
M-Finder: Uncovering functionally associated proteins from interactome data integrated with GO annotations.
PMID:24565382
Stringent DDI-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.
PMID:24564941
Identifying conserved protein complexes between species by constructing interolog networks.
PMID:24564762
RRHGE: a novel approach to classify the estrogen receptor based breast cancer subtypes.
PMID:24563630
Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration.
PMID:24550716
A Network Approach to Wound Healing.
PMID:24527361
Discovery and characterization of two Nimrod superfamily members in Anopheles gambiae.
PMID:24428830
Dynamics of regulatory networks in gastrin-treated adenocarcinoma cells.
PMID:24416123
Computational Prediction of Protein-Protein Interaction Networks: Algo-rithms and Resources.
PMID:24396273
Identifying functional transcription factor binding sites in yeast by considering their positional preference in the promoters.
PMID:24386279
Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data.
PMID:24385916
Reverse engineering molecular hypergraphs.
PMID:24384702
An association-adjusted consensus deleterious scheme to classify homozygous Mis-sense mutations for personal genome interpretation.
PMID:24365473
Identification of unstable network modules reveals disease modules associated with the progression of Alzheimer's disease.
PMID:24348898
Causal inference of gene regulation with subnetwork assembly from genetical genomics data.
PMID:24322297
SysBioCube: A Data Warehouse and Integrative Data Analysis Platform Facilitating Systems Biology Studies of Disorders of Military Relevance.
PMID:24303294
Expression of integrin alpha 10 is transcriptionally activated by pRb in mouse osteoblasts and is downregulated in multiple solid tumors.
PMID:24287699
Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer.
PMID:24278371
Protein function prediction by collective classification with explicit and implicit edges in protein-protein interaction networks.
PMID:24267980
P³DB 3.0: From plant phosphorylation sites to protein networks.
PMID:24243849
Integrating protein-protein interaction networks with phenotypes reveals signs of interactions.
PMID:24240319
Genotype to phenotype via network analysis.
PMID:24238873
Integrating in silico resources to map a signaling network.
PMID:24233784
Discovering disease-disease associations by fusing systems-level molecular data.
PMID:24232732
Bayesian network prior: network analysis of biological data using external knowledge.
PMID:24215027
Synthetic genetic targeting of genome instability in cancer.
PMID:24202319
High-resolution network biology: connecting sequence with function.
PMID:24197012
Conserved versatile master regulators in signalling pathways in response to stress in plants.
PMID:24147216
Systematic identification of transcriptional regulatory modules from protein-protein interaction networks.
PMID:24137002
NP-MuScL: unsupervised global prediction of interaction networks from multiple data sources.
PMID:24134391
Simple topological features reflect dynamics and modularity in protein interaction networks.
PMID:24130468
Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells.
PMID:24114839
Exploring mechanisms of human disease through structurally resolved protein interactome networks.
PMID:24096645
Identification of small exonic CNV from whole-exome sequence data and application to autism spectrum disorder.
PMID:24094742
Integration of new genes into cellular networks, and their structural maturation.
PMID:24056411
Detecting non-uniform clusters in large-scale interaction graphs.
PMID:24050498
PainNetworks: a web-based resource for the visualisation of pain-related genes in the context of their network associations.
PMID:24036287
IQdb: an intelligence quotient score-associated gene resource for human intelligence.
PMID:24030781
Predicting whole genome protein interaction networks from primary sequence data in model and non-model organisms using ENTS.
PMID:24015873
ExoCarta as a resource for exosomal research.
PMID:24009883
Inferring the effective TOR-dependent network: a computational study in yeast.
PMID:24005029
Research prioritization through prediction of future impact on biomedical science: a position paper on inference-analytics.
PMID:24001106
Computational analysis of virus-host interactomes.
PMID:23996253
Network clusters analysis based on protein-protein interaction network constructed in phosgene-induced acute lung injury.
PMID:23963411
Ultrasensitivity in phosphorylation-dephosphorylation cycles with little substrate.
PMID:23950701
Human growth is associated with distinct patterns of gene expression in evolutionarily conserved networks.
PMID:23941278
Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis.
PMID:23922650
Cloud-based uniform ChIP-Seq processing tools for modENCODE and ENCODE.
PMID:23875683
SMETANA: accurate and scalable algorithm for probabilistic alignment of large-scale biological networks.
PMID:23874484
Genome evolution predicts genetic interactions in protein complexes and reveals cancer drug targets.
PMID:23851603
Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development.
PMID:23847101
DBATE: database of alternative transcripts expression.
PMID:23842462
PhosphoChain: a novel algorithm to predict kinase and phosphatase networks from high-throughput expression data.
PMID:23832245
Mapping the functional yeast ABC transporter interactome.
PMID:23831759
Link clustering reveals structural characteristics and biological contexts in signed molecular networks.
PMID:23826198
BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge.
PMID:23819467
A nutrigenomic framework to identify time-resolving responses of hepatic genes in diet-induced obese mice.
PMID:23813319
Integrating sequence, expression and interaction data to determine condition-specific miRNA regulation.
PMID:23813013
A context-sensitive framework for the analysis of human signalling pathways in molecular interaction networks.
PMID:23812986
Arbor: comparative analysis workflows for the tree of life.
PMID:23811960
Mining breast cancer genes with a network based noise-tolerant approach.
PMID:23799982
Integrative approaches for predicting protein function and prioritizing genes for complex phenotypes using protein interaction networks.
PMID:23788799
ResponseNet2.0: Revealing signaling and regulatory pathways connecting your proteins and genes--now with human data.
PMID:23761447
Optimization criteria and biological process enrichment in homologous multiprotein modules.
PMID:23757502
Construction of protein phosphorylation networks by data mining, text mining and ontology integration: analysis of the spindle checkpoint.
PMID:23749465
The development of a universal in silico predictor of protein-protein interactions.
PMID:23741499
Comparison of modules of wild type and mutant Huntingtin and TP53 protein interaction networks: implications in biological processes and functions.
PMID:23741403
Passing messages between biological networks to refine predicted interactions.
PMID:23741402
Integrated analysis of recurrent properties of cancer genes to identify novel drivers.
PMID:23718799
NRF2-ome: an integrated web resource to discover protein interaction and regulatory networks of NRF2.
PMID:23710289
Genome-wide methylated DNA immunoprecipitation analysis of patients with polycystic ovary syndrome.
PMID:23705014
Evolutionary pressure on the topology of protein interface interaction networks.
PMID:23701316
A genome-wide resource of cell cycle and cell shape genes of fission yeast.
PMID:23697806
A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis.
PMID:23696811
Human monogenic disease genes have frequently functionally redundant paralogs.
PMID:23696728
Interface-resolved network of protein-protein interactions.
PMID:23696724
Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
PMID:23695164
Adjusting for High-dimensional Covariates in Sparse Precision Matrix Estimation by ℓ1-Penalization.
PMID:23687392
The PhosphoGRID Saccharomyces cerevisiae protein phosphorylation site database: version 2.0 update.
PMID:23674503
All or nothing: protein complexes flip essentiality between distantly related eukaryotes.
PMID:23661563
Protein complex detection via weighted ensemble clustering based on Bayesian nonnegative matrix factorization.
PMID:23658709
Genotype to phenotype mapping and the fitness landscape of the E. coli lac promoter.
PMID:23650500
Top-down network analysis to drive bottom-up modeling of physiological processes.
PMID:23641868
PCorral--interactive mining of protein interactions from MEDLINE.
PMID:23640984
Use of the protein ontology for multi-faceted analysis of biological processes: a case study of the spindle checkpoint.
PMID:23637705
Chapter 15: disease gene prioritization.
PMID:23633938
Genome-wide association study of sleep in Drosophila melanogaster.
PMID:23617951
Large-scale event extraction from literature with multi-level gene normalization.
PMID:23613707
INstruct: a database of high-quality 3D structurally resolved protein interactome networks.
PMID:23599502
Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types.
PMID:23595227
Evolutionary capacitance and control of protein stability in protein-protein interaction networks.
PMID:23592969
Physical and genetic-interaction density reveals functional organization and informs significance cutoffs in genome-wide screens.
PMID:23589890
Endometrial receptivity: a revisit to functional genomics studies on human endometrium and creation of HGEx-ERdb.
PMID:23555582
Comparison of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and combined HCC-CC (CHC) with each other based on microarray dataset.
PMID:23532688
Network pharmacology strategies toward multi-target anticancer therapies: from computational models to experimental design principles.
PMID:23530504
Functional knowledge transfer for high-accuracy prediction of under-studied biological processes.
PMID:23516347
Functional site plasticity in domain superfamilies.
PMID:23499848
Preferential duplication of intermodular hub genes: an evolutionary signature in eukaryotes genome networks.
PMID:23468868
Predicting the binding patterns of hub proteins: a study using yeast protein interaction networks.
PMID:23431393
Using BioBin to explore rare variant population stratification.
PMID:23424138
Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit.
PMID:23424120
Epigenetic epistatic interactions constrain the evolution of gene expression.
PMID:23423319
Quantitative analysis of chaperone network throughput in budding yeast.
PMID:23420633
A genomic toolkit to investigate kinesin and myosin motor function in cells.
PMID:23417121
Linking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signaling.
PMID:23408876
Benchmarking human protein complexes to investigate drug-related systems and evaluate predicted protein complexes.
PMID:23405067
Interactome3D: adding structural details to protein networks.
PMID:23399932
A survey of protein interaction data and multigenic inherited disorders.
PMID:23398688
The 3rd DBCLS BioHackathon: improving life science data integration with Semantic Web technologies.
PMID:23398680
The YeastGenome app: the Saccharomyces Genome Database at your fingertips.
PMID:23396302
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review.
PMID:23384594
Identification of ovarian cancer associated genes using an integrated approach in a Boolean framework.
PMID:23383610
Turning gold into 'junk': transposable elements utilize central proteins of cellular networks.
PMID:23341038
Predicting PDZ domain mediated protein interactions from structure.
PMID:23336252
SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks.
PMID:23331499
Identification of new protein interactions between dengue fever virus and its hosts, human and mosquito.
PMID:23326450
Systems biology approach reveals genome to phenome correlation in type 2 diabetes.
PMID:23308243
Evidence for the robustness of protein complexes to inter-species hybridization.
PMID:23300466
Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.
PMID:23300433
Distinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions.
PMID:23295670
Supervised maximum-likelihood weighting of composite protein networks for complex prediction.
PMID:23281936
Helminth secretome database (HSD): a collection of helminth excretory/secretory proteins predicted from expressed sequence tags (ESTs).
PMID:23281827
GWIDD: a comprehensive resource for genome-wide structural modeling of protein-protein interactions.
PMID:23245398
A gene ontology inferred from molecular networks.
PMID:23242164
A novel link prediction algorithm for reconstructing protein-protein interaction networks by topological similarity.
PMID:23235927
Building an efficient curation workflow for the Arabidopsis literature corpus.
PMID:23221298
Mitotic exit and separation of mother and daughter cells.
PMID:23212898
An evolutionarily conserved innate immunity protein interaction network.
PMID:23209288
Identification of pharmacological targets in amyotrophic lateral sclerosis through genomic analysis of deregulated genes and pathways.
PMID:23204922
The BioGRID interaction database: 2013 update.
PMID:23203989
STRING v9.1: protein-protein interaction networks, with increased coverage and integration.
PMID:23203871
The Disease and Gene Annotations (DGA): an annotation resource for human disease.
PMID:23197658
SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining.
PMID:23193286
The TissueNet database of human tissue protein-protein interactions.
PMID:23193266
Systems biology of pathogen-host interaction: networks of protein-protein interaction within pathogens and pathogen-human interactions in the post-genomic era.
PMID:23193100
Evolutionary rate and duplicability in the Arabidopsis thaliana protein-protein interaction network.
PMID:23160177
Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions.
PMID:23157382
Discovery of cell compartment specific protein-protein interactions using affinity purification combined with tandem mass spectrometry.
PMID:23157168
Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction.
PMID:23146171
The ConsensusPathDB interaction database: 2013 update.
PMID:23143270
A travel guide to Cytoscape plugins.
PMID:23132118
Spliceosome database: a tool for tracking components of the spliceosome.
PMID:23118483
SpliceAid-F: a database of human splicing factors and their RNA-binding sites.
PMID:23118479
Identifying novel protein complexes in cancer cells using epitope-tagging of endogenous human genes and affinity-purification mass spectrometry.
PMID:23106643
Popular computational methods to assess multiprotein complexes derived from label-free affinity purification and mass spectrometry (AP-MS) experiments.
PMID:23071097
Dr. PIAS 2.0: an update of a database of predicted druggable protein-protein interactions.
PMID:23060433
Aminopropyltransferases involved in polyamine biosynthesis localize preferentially in the nucleus of plant cells.
PMID:23056524
Identification of significant pathways in gastric cancer based on protein-protein interaction networks and cluster analysis.
PMID:23055812
PRD: A protein-RNA interaction database.
PMID:23055619
Cluster-based assessment of protein-protein interaction confidence.
PMID:23050565
Evaluating caveolin interactions: do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif?
PMID:23028656
Tissue-specific functional networks for prioritizing phenotype and disease genes.
PMID:23028291
Protein stickiness, rather than number of functional protein-protein interactions, predicts expression noise and plasticity in yeast.
PMID:23017156
Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs.
PMID:22976491
RhesusBase: a knowledgebase for the monkey research community.
PMID:22965133
Identifying functional modules in interaction networks through overlapping Markov clustering.
PMID:22962469
Architecture of the human regulatory network derived from ENCODE data.
PMID:22955619
Feature Identification of Compensatory Gene Pairs without Sequence Homology in Yeast.
PMID:22952430
Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data.
PMID:22948730
Analyzing protein-protein interactions from affinity purification-mass spectrometry data with SAINT.
PMID:22948729
A network-based approach for predicting missing pathway interactions.
PMID:22916002
A network synthesis model for generating protein interaction network families.
PMID:22912671
A SPARSE CONDITIONAL GAUSSIAN GRAPHICAL MODEL FOR ANALYSIS OF GENETICAL GENOMICS DATA.
PMID:22905077
Minireview: progress and challenges in proteomics data management, sharing, and integration.
PMID:22902541
Identifying biologically interpretable transcription factor knockout targets by jointly analyzing the transcription factor knockout microarray and the ChIP-chip data.
PMID:22898448
Screening of candidate genes for primary open angle glaucoma.
PMID:22876139
HINT: High-quality protein interactomes and their applications in understanding human disease.
PMID:22846459
Computational framework for analysis of prey-prey associations in interaction proteomics identifies novel human protein-protein interactions and networks.
PMID:22845868
Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments.
PMID:22844098
atBioNet--an integrated network analysis tool for genomics and biomarker discovery.
PMID:22817640
INDI: a computational framework for inferring drug interactions and their associated recommendations.
PMID:22806140
Endosomal crosstalk: meeting points for signaling pathways.
PMID:22796207
The core regulation module of stress-responsive regulatory networks in yeast.
PMID:22784859
Combinatorial drug therapy for cancer in the post-genomic era.
PMID:22781697
Integrating genome and functional genomics data to reveal perturbed signaling pathways in ovarian cancers.
PMID:22779056
Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations.
PMID:22761558
Accuracy improvement in protein complex prediction from protein interaction networks by refining cluster overlaps.
PMID:22759580
Genes2FANs: connecting genes through functional association networks.
PMID:22748121
MC EMiNEM maps the interaction landscape of the Mediator.
PMID:22737066
Detecting mutually exclusive interactions in protein-protein interaction maps.
PMID:22715412
Beyond hairballs: The use of quantitative mass spectrometry data to understand protein-protein interactions.
PMID:22710165
DEFOG: discrete enrichment of functionally organized genes.
PMID:22706384
Dynamic network of transcription and pathway crosstalk to reveal molecular mechanism of MGd-treated human lung cancer cells.
PMID:22693540
MoNetFamily: a web server to infer homologous modules and module-module interaction networks in vertebrates.
PMID:22689643
BIPS: BIANA Interolog Prediction Server. A tool for protein-protein interaction inference.
PMID:22689642
IMP: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks.
PMID:22684505
Hierarchical modularity and the evolution of genetic interactomes across species.
PMID:22681890
MAGNET: MicroArray Gene expression and Network Evaluation Toolkit.
PMID:22669910
A topology-based metric for measuring term similarity in the gene ontology.
PMID:22666244
An interaction map of endoplasmic reticulum chaperones and foldases.
PMID:22665516
Integrated analysis of transcriptome and lipid profiling reveals the co-influences of inositol-choline and Snf1 in controlling lipid biosynthesis in yeast.
PMID:22622761
MGEx-Udb: a mammalian uterus database for expression-based cataloguing of genes across conditions, including endometriosis and cervical cancer.
PMID:22606288
Prediction and comparison of Salmonella-human and Salmonella-Arabidopsis interactomes.
PMID:22589098
Mycobacterium tuberculosis and Clostridium difficille interactomes: demonstration of rapid development of computational system for bacterial interactome prediction.
PMID:22587966
The human proteome - a scientific opportunity for transforming diagnostics, therapeutics, and healthcare.
PMID:22583803
M-Track: detecting short-lived protein-protein interactions in vivo.
PMID:22581371
Exploring the yeast acetylome using functional genomics.
PMID:22579291
Functional and topological characterization of transcriptional cooperativity in yeast.
PMID:22574744
Linking proteins to signaling pathways for experiment design and evaluation.
PMID:22558382
System approaches reveal the molecular networks involved in neural stem cell differentiation.
PMID:22492180
Swimming upstream: identifying proteomic signals that drive transcriptional changes using the interactome and multiple "-omics" datasets.
PMID:22482945
Integrated inference and analysis of regulatory networks from multi-level measurements.
PMID:22482944
Network-based functional enrichment.
PMID:22479706
The protein expression landscape of the Arabidopsis root.
PMID:22447775
A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division.
PMID:22438835
How to link ontologies and protein-protein interactions to literature: text-mining approaches and the BioCreative experience.
PMID:22438567
An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells.
PMID:22416242
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly.
PMID:22416125
Purification of the COP9 signalosome complex and binding partners from human T cells.
PMID:22414063
Reducing false-positive prediction of minimotifs with a genetic interaction filter.
PMID:22403687
AtPAN: an integrated system for reconstructing transcriptional regulatory networks in Arabidopsis thaliana.
PMID:22397531
The role of structural disorder in the rewiring of protein interactions through evolution.
PMID:22389433
Transparent mediation-based access to multiple yeast data sources using an ontology driven interface.
PMID:22372975
Detection of interacting transcription factors in human tissues using predicted DNA binding affinity.
PMID:22369666
Transcriptional activity and nuclear localization of Cabut, the Drosophila ortholog of vertebrate TGF-β-inducible early-response gene (TIEG) proteins.
PMID:22359651
Short Co-occurring Polypeptide Regions Can Predict Global Protein Interaction Maps.
PMID:22355752
HIPPIE: Integrating protein interaction networks with experiment based quality scores.
PMID:22348130
Infection Strategies of Bacterial and Viral Pathogens through Pathogen-Human Protein-Protein Interactions.
PMID:22347880
Rewiring of PDZ domain-ligand interaction network contributed to eukaryotic evolution.
PMID:22346764
ANAP: an integrated knowledge base for Arabidopsis protein interaction network analysis.
PMID:22345505
The identification of short linear motif-mediated interfaces within the human interactome.
PMID:22328783
Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK.
PMID:22318606
Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
PMID:22287626
Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies.
PMID:22272186
Differential network biology.
PMID:22252388
The genetic control of growth rate: a systems biology study in yeast.
PMID:22244311
IMID: integrated molecular interaction database.
PMID:22238258
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action.
PMID:22235860
Prediction and characterization of protein-protein interaction networks in swine.
PMID:22230699
Tramtrack is genetically upstream of genes controlling tracheal tube size in Drosophila.
PMID:22216153
Evolution of biological interaction networks: from models to real data.
PMID:22204388
Molecular links between cellular senescence, longevity and age-related diseases - a systems biology perspective.
PMID:22184282
RefNetBuilder: a platform for construction of integrated reference gene regulatory networks from expressed sequence tags.
PMID:22166047
The dichotomy in degree correlation of biological networks.
PMID:22164269
The Protein-Protein Interaction tasks of BioCreative III: classification/ranking of articles and linking bio-ontology concepts to full text.
PMID:22151929
Benchmarking of the 2010 BioCreative Challenge III text-mining competition by the BioGRID and MINT interaction databases.
PMID:22151178
The Arabidopsis Information Resource (TAIR): improved gene annotation and new tools.
PMID:22140109
AutismKB: an evidence-based knowledgebase of autism genetics.
PMID:22139918
iRefR: an R package to manipulate the iRefIndex consolidated protein interaction database.
PMID:22115179
modMine: flexible access to modENCODE data.
PMID:22080565
AnimalTFDB: a comprehensive animal transcription factor database.
PMID:22080564
Network of Cancer Genes (NCG 3.0): integration and analysis of genetic and network properties of cancer genes.
PMID:22080562
Systematic exploration of synergistic drug pairs.
PMID:22068327
WormBase 2012: more genomes, more data, new website.
PMID:22067452
PINA v2.0: mining interactome modules.
PMID:22067443
InterEvol database: exploring the structure and evolution of protein complex interfaces.
PMID:22053089
PomBase: a comprehensive online resource for fission yeast.
PMID:22039153
Heat shock partially dissociates the overlapping modules of the yeast protein-protein interaction network: a systems level model of adaptation.
PMID:22022244
PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae.
PMID:22009677
Systems-biology approaches to discover anti-viral effectors of the human innate immune response.
PMID:21994773
Gadd45 proteins: relevance to aging, longevity and age-related pathologies.
PMID:21986581
Structural analysis of hubs in human NR-RTK network.
PMID:21974810
Global identification of modular cullin-RING ligase substrates.
PMID:21963094
Using the Saccharomyces Genome Database (SGD) for analysis of genomic information.
PMID:21901739
ppiTrim: constructing non-redundant and up-to-date interactomes.
PMID:21873645
Conserved and differential gene interactions in dynamical biological systems.
PMID:21840874
Prediction of body fluids where proteins are secreted into based on protein interaction network.
PMID:21829572
Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae.
PMID:21825077
Reactome pathway analysis to enrich biological discovery in proteomics data sets.
PMID:21751369
g:Profiler--a web server for functional interpretation of gene lists (2011 update).
PMID:21646343
A network of SCOP hidden Markov models and its analysis.
PMID:21635719
SLiMSearch 2.0: biological context for short linear motifs in proteins.
PMID:21622654
CASCADE_SCAN: mining signal transduction network from high-throughput data based on steepest descent method.
PMID:21575263
Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae.
PMID:21518805
Sig2BioPAX: Java tool for converting flat files to BioPAX Level 3 format.
PMID:21418653
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community.
PMID:21261995
Protein databases on the internet.
PMID:18265344