Gene Ontology
Names
More detailed information about this field from each metasource.
Gene Ontology
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Biontology / Bioportal
version: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
GO
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Biontology / Bioportal
version: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
metasource: BiŌkeanós-Medsourcing
version: 0.0.1:2022-11-04T13:34:25.975929
Gene Ontology (GO)
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:12.564649
go
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:12.564649
Names
More detailed information about this field from each metasource.
Gene Ontology
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Biontology / Bioportal
version: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
GO
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Biontology / Bioportal
version: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
metasource: BiŌkeanós-Medsourcing
version: 0.0.1:2022-11-04T13:34:25.975929
Gene Ontology (GO)
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:12.564649
go
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:12.564649
Other names: GO, Gene Ontology (GO), go
Names
More detailed information about this field from each metasource.
Gene Ontology
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Biontology / Bioportal
version: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
GO
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Biontology / Bioportal
version: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
metasource: BiŌkeanós-Medsourcing
version: 0.0.1:2022-11-04T13:34:25.975929
Gene Ontology (GO)
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:12.564649
go
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:12.564649
The Gene Ontology resource provides a computational representation of our current scientific knowledge about the functions of genes (or, more properly, the protein and non-coding RNA molecules produced by genes) from many different organisms, from humans to bacteria. It describes our knowledge of the biological domain with respect to three aspects: Molecular Function (molecular-level activities performed by gene products), Cellular Component (locations in cellular structures in which a gene product performs a function, Biological Process (‘biological programs’ done by multiple molecular activities, not pathway). Those are semi-disjoint - no is_a link between the 3 but other like part_of and regulates exist.
Description
More detailed information about this field from each metasource.
The Gene Ontology resource provides a computational representation of our current scientific knowledge about the functions of genes (or, more properly, the protein and non-coding RNA molecules produced by genes) from many different organisms, from humans to bacteria. It describes our knowledge of the biological domain with respect to three aspects: Molecular Function (molecular-level activities performed by gene products), Cellular Component (locations in cellular structures in which a gene product performs a function, Biological Process (‘biological programs’ done by multiple molecular activities, not pathway). Those are semi-disjoint - no is_a link between the 3 but other like part_of and regulates exist.
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
The Gene Ontology (GO) is a structured vocabulary for use by the research community for the annotation of genes, gene products and sequences. The GO defines concepts/classes used to describe gene function and relationships between these concepts.
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Provides structured controlled vocabularies for the annotation of gene products with respect to their molecular function, cellular component, and biological role. The Gene Ontology consists of three Vocabularies.
metasource: Biontology / Bioportalversion: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the past two years. The new GO-CAM annotation framework was notably improved, and we formalized the model with a computational schema to check and validate the rapidly increasing repository of 2838 GO-CAMs. In addition, we describe the impacts of several collaborations to refine GO and report a 10% increase in the number of GO annotations, a 25% increase in annotated gene products, and over 9,400 new scientific articles annotated. As the project matures, we continue our efforts to review older annotations in light of newer findings, and, to maintain consistency with other ontologies. As a result, 20 000 annotations derived from experimental data were reviewed, corresponding to 2.5% of experimental GO annotations. The website (http://geneontology.org) was redesigned for quick access to documentation, downloads and tools. To maintain an accurate resource and support traceability and reproducibility, we have made available a historical archive covering the past 15 years of GO data with a consistent format and file structure for both the ontology and annotations.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
The Gene Ontology Consortium continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. Several new relationship types have been introduced and used, along with existing relationships, to create links between and within the domains. Gene product annotation continues to increase both in the number of total annotations and in species coverage. Tools have seen major improvements in functionality, speed and usage.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:12.564649
Webpage:
http://geneontology.orgWebpage
More detailed information about this field from each metasource.
http://geneontology.org
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
http://www.geneontology.org
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Biontology / Bioportal
version: 2022-10-07 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/GO
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
http://www.geneontology.org/
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:12.564649
Licence:
Name: Creative Commons Attribution v4.0Licence name
More detailed information about this field from each metasource.
Creative Commons Attribution v4.0
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
Creative Commons Attribution 4.0 International (CC BY 4.0)
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Licence URL
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http://geneontology.org/docs/go-citation-policy/
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
https://creativecommons.org/licenses/by/4.0/
metasource: Fairsharing.orgversion: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Publications:
(12)
Publications
More detailed information about this field from each metasource.
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
PMID: 10802651
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
The Gene Ontology (GO) database and informatics resource
PMID: 14681407
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
The Gene Ontology Resource: 20 years and still GOing strong
PMID: 30395331
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Gene Ontology Consortium: going forward
PMID: 25428369
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Gene Ontology annotations and resources
PMID: 23161678
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
The Gene Ontology in 2010: extensions and refinements
PMID: 19920128
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:12.564649
The Gene Ontology: enhancements for 2011
PMID: 22102568
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:12.564649
The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species
PMID: 19578431
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Dovetailing biology and chemistry: integrating the Gene Ontology with the ChEBI chemical ontology
PMID: 23895341
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037419/
metasource: BiŌkeanós-Medsourcing
version: 0.0.1:2022-11-04T13:34:25.975929
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323945/
metasource: BiŌkeanós-Medsourcing
version: 0.0.1:2022-11-04T13:34:25.975929
https://doi.org/10.1093/nar/gkaa1113
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
PMID: 10802651
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
The Gene Ontology (GO) database and informatics resource
PMID: 14681407
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
The Gene Ontology Resource: 20 years and still GOing strong
PMID: 30395331
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Gene Ontology Consortium: going forward
PMID: 25428369
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Gene Ontology annotations and resources
PMID: 23161678
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
The Gene Ontology in 2010: extensions and refinements
PMID: 19920128
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:12.564649
The Gene Ontology: enhancements for 2011
PMID: 22102568
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:12.564649
The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species
PMID: 19578431
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Dovetailing biology and chemistry: integrating the Gene Ontology with the ChEBI chemical ontology
PMID: 23895341
metasource: Fairsharing.org
version: FAIRsharing.org: GO; Gene Ontology; DOI: https://doi.org/10.25504/FAIRsharing.6xq0ee; Last edited: Nov. 22, 2020, 3:16 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037419/
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323945/
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
https://doi.org/10.1093/nar/gkaa1113
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
PubMed citations: 9999.
9999 articles citing: Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex. PMID:35915179
Genome sequence and comparative analysis of fungal antagonistic strain Bacillus velezensis LJBV19. PMID:35913660
Transcriptome and Metabolome Analyses Reveal the Involvement of Multiple Pathways in Flowering Intensity in Mango. PMID:35909785
The Construction and Analysis of Infiltrating Immune Cell and ceRNA Networks in Diabetic Foot Ulcer. PMID:35909542
FLASHIda enables intelligent data acquisition for top-down proteomics to boost proteoform identification counts. PMID:35906205
Mutations in SORL1 and MTHFDL1 possibly contribute to the development of Alzheimer's disease in a multigenerational Colombian Family. PMID:35905044
Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. PMID:35902728
Dynamic Transcriptomic Profiling During Liver Development in Schizothorax Prenanti. PMID:35899028
Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis. PMID:35898629
Bioinformatics Analysis Identifies Potential Ferroptosis Key Gene in Type 2 Diabetic Islet Dysfunction. PMID:35898457
Characterizing the extracellular matrix transcriptome of cervical, endometrial, and uterine cancers. PMID:35898192
Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer. PMID:35897761
Taste 2 Receptor Is Involved in Differentiation of 3T3-L1 Preadipocytes. PMID:35897692
In silico development and experimental validation of a novel 7-gene signature based on PI3K pathway-related genes in bladder cancer. PMID:35896848
Ribosomal RNA-Depletion Provides an Efficient Method for Successful Dual RNA-Seq Expression Profiling of a Marine Sponge Holobiont. PMID:35895230
Pan-Cancer Analysis Reveals the Prognostic Potential of the THAP9/THAP9-AS1 Sense-Antisense Gene Pair in Human Cancers. PMID:35893234
Activation of Oncogenic and Immune-Response Pathways Is Linked to Disease-Specific Survival in Merkel Cell Carcinoma. PMID:35892849
Use of Autoreactive Antibodies in Blood of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN) for Grade Distinction and Detection of Malignancy. PMID:35892825
AKT1 Transcriptomic Landscape in Breast Cancer Cells. PMID:35892586
Genome-Wide Association Analysis and Genetic Parameters for Feed Efficiency and Related Traits in Yorkshire and Duroc Pigs. PMID:35892552
An accurate prediction model of digenic interaction for estimating pathogenic gene pairs of human diseases. PMID:35891796
The Protective Effect of Edaravone on TDP-43 Plus Oxidative Stress-Induced Neurotoxicity in Neuronal Cells: Analysis of Its Neuroprotective Mechanisms Using RNA Sequencing. PMID:35890141
Characterization of Cronobacter sakazakii Strains Originating from Plant-Origin Foods Using Comparative Genomic Analyses and Zebrafish Infectivity Studies. PMID:35889115
Transcriptional Profiling of Leishmania infantum Infected Dendritic Cells: Insights into the Role of Immunometabolism in Host-Parasite Interaction. PMID:35888991
A Current Encyclopedia of Bioinformatics Tools, Data Formats and Resources for Mass Spectrometry Lipidomics. PMID:35888710
Role of PsnWRKY70 in Regulatory Network Response to Infection with Alternaria alternata (Fr.) Keissl in Populus. PMID:35886886
REDfly: An Integrated Knowledgebase for Insect Regulatory Genomics. PMID:35886794
Systematic Functional Annotation Workflow for Insects. PMID:35886762
A Narrative Literature Review of Natural Language Processing Applied to the Occupational Exposome. PMID:35886395
Identification of New Toxicity Mechanisms in Drug-Induced Liver Injury through Systems Pharmacology. PMID:35886075
Identification of Differential Expression Genes between Volume and Pressure Overloaded Hearts Based on Bioinformatics Analysis. PMID:35886059
Genomic Characterization by Whole-Exome Sequencing of Hypermobility Spectrum Disorder. PMID:35886052
Exploring the Mutational Landscape of Isolated Congenital Heart Defects: An Exome Sequencing Study Using Cardiac DNA. PMID:35885997
Genome-Wide Evolutionary Analysis of Putative Non-Specific Herbicide Resistance Genes and Compilation of Core Promoters between Monocots and Dicots. PMID:35885954
Whole Transcriptome Sequencing Reveals Drought Resistance-Related Genes in Upland Cotton. PMID:35885942
Comparative Transcriptome Profiling Reveals the Genes Involved in Storage Root Expansion in Sweetpotato (Ipomoea batatas (L.) Lam.). PMID:35885939
EGFAFS: A Novel Feature Selection Algorithm Based on Explosion Gravitation Field Algorithm. PMID:35885095
New Evidence of Tiger Subspecies Differentiation and Environmental Adaptation: Comparison of the Whole Genomes of the Amur Tiger and the South China Tiger. PMID:35883364
Gene Updater: a web tool that autocorrects and updates for Excel misidentified gene names. PMID:35882976
Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration. PMID:35882847
Aging endometrium in young women: molecular classification of endometrial aging-based markers in women younger than 35 years with recurrent implantation failure. PMID:35881273
Genome-Wide Analysis of microRNAs Identifies the Lipid Metabolism Pathway to Be a Defining Factor in Adipose Tissue From Different Sheep. PMID:35880040
Pan-cancer integrative analysis of whole-genome De novo somatic point mutations reveals 17 cancer types. PMID:35879674
Integration of probabilistic functional networks without an external Gold Standard. PMID:35879662
A supervised protein complex prediction method with network representation learning and gene ontology knowledge. PMID:35879648
Characterization of methylation patterns associated with lifestyle factors and vitamin D supplementation in a healthy elderly cohort from Southwest Sweden. PMID:35879377
Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153. PMID:35879285
Mechanisms of Action of Semen Ziziphi spinosae in the Treatment of Tourette Syndrome. PMID:35875687
Venom composition of Trimeresurus albolabris, T. insularis, T. puniceus and T. purpureomaculatus from Indonesia. PMID:35875602
Methylated RNA Immunoprecipitation Sequencing Reveals the m6A Landscape in Oral Squamous Cell Carcinoma. PMID:35874897
The Culture Dish Surface Influences the Phenotype and Dissociation Strategy in Distinct Mouse Macrophage Populations. PMID:35874686
Protocol for establishing a protein-protein interaction network using tandem affinity purification followed by mass spectrometry in mammalian cells. PMID:35874475
Chromatin Separation Regulators Predict the Prognosis and Immune Microenvironment Estimation in Lung Adenocarcinoma. PMID:35873497
Exploration of the Mechanisms of Differential Indole Alkaloid Biosynthesis in Dedifferentiated and Cambial Meristematic Cells of Catharanthus roseus Using Transcriptome Sequencing. PMID:35873460
Unveiling Co-Infection in Cystic Fibrosis Airways: Transcriptomic Analysis of Pseudomonas aeruginosa and Staphylococcus aureus Dual-Species Biofilms. PMID:35873457
Interspecies Isobaric Labeling-Based Quantitative Proteomics Reveals Protein Changes in the Ovary of Aedes aegypti Coinfected With ZIKV and Wolbachia. PMID:35873163
orsum: a Python package for filtering and comparing enrichment analyses using a simple principle. PMID:35870894
Gene expression profiling before and after internode culture for adventitious shoot formation in ipecac. PMID:35869421
Identification of microRNAs and their target genes related to the accumulation of anthocyanin in purple potato tubers (Solanum tuberosum). PMID:35865074
Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats. PMID:35864448
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex. PMID:35864088
Network Pharmacology-Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury. PMID:35860733
Increased Development of Th1, Th17, and Th1.17 Cells Under T1 Polarizing Conditions in Juvenile Idiopathic Arthritis. PMID:35860254
Virofree, an Herbal Medicine-Based Formula, Interrupts the Viral Infection of Delta and Omicron Variants of SARS-CoV-2. PMID:35860023
N6-methyladenosine modulates long non-coding RNA in the developing mouse heart. PMID:35858921
Cancer-associated fibroblast-derived exosomal microRNA-20a suppresses the PTEN/PI3K-AKT pathway to promote the progression and chemoresistance of non-small cell lung cancer. PMID:35857905
Revealing the difference of α-amylase and CYP6AE76 gene between polyphagous Conogethes punctiferalis and oligophagous C. pinicolalis by multiple-omics and molecular biological technique. PMID:35854244
TMT-based proteomic analysis of liquorice root in response to drought stress. PMID:35854220
Prospective role and immunotherapeutic targets of sideroflexin protein family in lung adenocarcinoma: evidence from bioinformatics validation. PMID:35851932
Analysis on the desert adaptability of indigenous sheep in the southern edge of Taklimakan Desert. PMID:35851076
Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer's disease. PMID:35849618
From Transcriptomics, Metabolomics to Functional Studies: Extracellular ATP Induces TGF-β-Like Epithelial Mesenchymal Transition in Lung Cancer Cells. PMID:35847855
A Computational Framework to Characterize the Cancer Drug Induced Effect on Aging Using Transcriptomic Data. PMID:35847024
Identification of a Prognostic Model Based on Fatty Acid Metabolism-Related Genes of Head and Neck Squamous Cell Carcinoma. PMID:35846149
Transcriptomic Insight into Viviparous Growth in Water Lily. PMID:35845943
Excessive Sodium Intake Leads to Cardiovascular Disease by Promoting Sex-Specific Dysfunction of Murine Heart. PMID:35845798
Network pharmacology-based analysis of the effects of puerarin on sarcopenia. PMID:35845507
Ferroptosis and Autophagy-Related Genes in the Pathogenesis of Ischemic Cardiomyopathy. PMID:35845045
Single-Cell RNA Sequencing Unravels Upregulation of Immune Cell Crosstalk in Relapsed Pediatric Ependymoma. PMID:35844565
Isolation, Identification, and Investigation of Pathogenic Bacteria From Common Carp (Cyprinus carpio) Naturally Infected With Plesiomonas shigelloides. PMID:35844551
Diagnostic and Predictive Values of Ferroptosis-Related Genes in Child Sepsis. PMID:35844488
Time and phenotype-dependent transcriptome analysis in AAV-TGFβ1 and Bleomycin-induced lung fibrosis models. PMID:35842487
Protein expression profiling identifies a prognostic model for ovarian cancer. PMID:35840928
MiR-30c-1-3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms. PMID:35840740
Vascular Regulation by Super Enhancer-Derived LINC00607. PMID:35837599
De novo Transcriptome Analysis of Drought-Adapted Cluster Bean (Cultivar RGC-1025) Reveals the Wax Regulatory Genes Involved in Drought Resistance. PMID:35837463
Genome-Wide Dissection of the Genetic Basis for Drought Tolerance in Gossypium hirsutum L. Races. PMID:35837453
Dissecting the Genetic Structure of Maize Leaf Sheaths at Seedling Stage by Image-Based High-Throughput Phenotypic Acquisition and Characterization. PMID:35837446
A TP53 Related Immune Prognostic Model for the Prediction of Clinical Outcomes and Therapeutic Responses in Lung Adenocarcinoma. PMID:35837383
Identification and Validation of Autophagy-Related Genes in Primary Ovarian Insufficiency by Gene Expression Profile and Bioinformatic Analysis. PMID:35837294
Weighted Gene Correlation Network Analysis (WGCNA) of Arabidopsis Somatic Embryogenesis (SE) and Identification of Key Gene Modules to Uncover SE-Associated Hub Genes. PMID:35837132
Arecoline promotes proliferation and migration of human HepG2 cells through activation of the PI3K/AKT/mTOR pathway. PMID:35836300
Differential expression profile and in-silico functional analysis of long noncoding RNA and mRNA in duck embryo fibroblasts infected with duck plague virus. PMID:35836133
Comparative transcriptomics identifies candidate genes involved in the evolutionary transition from dehiscent to indehiscent fruits in Lepidium (Brassicaceae). PMID:35836106
Transcriptome analysis and phenotyping of walnut seedling roots under nitrogen stresses. PMID:35835799
Antioxidant Mechanism of Lactiplantibacillus plantarum KM1 Under H2O2 Stress by Proteomics Analysis. PMID:35832808
Comprehensive Genome-Wide Identification and Expression Profiling of Eceriferum (CER) Gene Family in Passion Fruit (Passiflora edulis) Under Fusarium kyushuense and Drought Stress Conditions. PMID:35832215
Chromosome-scale assembly and annotation of the perennial ryegrass genome. PMID:35831814
Quantitative proteomics analysis to assess protein expression levels in the ovaries of pubescent goats. PMID:35831802
Selective expression of variant surface antigens enables Plasmodium falciparum to evade immune clearance in vivo. PMID:35831417
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery. PMID:35831314
Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis. PMID:35821263
The heterogeneous pharmacological medical biochemical network PharMeBINet. PMID:35821017
Alternative splicing patterns reveal prognostic indicator in muscle-invasive bladder cancer. PMID:35820925
Spatially resolved proteomic map shows that extracellular matrix regulates epidermal growth. PMID:35817779
Proteomic characterisation of triple negative breast cancer cells following CDK4/6 inhibition. PMID:35817775
The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals. PMID:35816093
Features and Colonization Strategies of Enterococcus faecalis in the Gut of Bombyx mori. PMID:35814682
Dengue Virus-2 Infection Affects Fecundity and Elicits Specific Transcriptional Changes in the Ovaries of Aedes aegypti Mosquitoes. PMID:35814655
Beneficial Effect of Selenium Doped Carbon Quantum Dots Supplementation on the in vitro Development Competence of Ovine Oocytes. PMID:35814612
Exosome-mediated transduction of mechanical force regulates prostate cancer migration via microRNA. PMID:35812347
Integrated Transcriptome Profiling Identifies Prognostic Hub Genes as Therapeutic Targets of Glioblastoma: Evidenced by Bioinformatics Analysis. PMID:35811900
Metabolome and transcriptome profiling reveal regulatory network and mechanism of flavonoid biosynthesis during color formation of Dioscorea cirrhosa L. PMID:35811818
Identification and Validation of Candidate Gene Module Along With Immune Cells Infiltration Patterns in Atherosclerosis Progression to Plaque Rupture via Transcriptome Analysis. PMID:35811739
Lilac (Syringa oblata) genome provides insights into its evolution and molecular mechanism of petal color change. PMID:35810211
Single-cell RNA sequencing reveals localized tumour ablation and intratumoural immunostimulant delivery potentiate T cell mediated tumour killing. PMID:35808806
Lim Domain Binding 3 (Ldb3) Identified as a Potential Marker of Cardiac Extracellular Vesicles. PMID:35806378
Genome Assembly and Analysis of the Flavonoid and Phenylpropanoid Biosynthetic Pathways in Fingerroot Ginger (Boesenbergia rotunda). PMID:35806276
Semantics of Dairy Fermented Foods: A Microbiologist's Perspective. PMID:35804753
Gene function prediction in five model eukaryotes exclusively based on gene relative location through machine learning. PMID:35803984
Upper airway gene expression shows a more robust adaptive immune response to SARS-CoV-2 in children. PMID:35803954
Lipolysis regulates major transcriptional programs in brown adipocytes. PMID:35803907
The role of toll-like receptors (TLRs) in pan-cancer. PMID:35801728
New Mutations in cls Lead to Daptomycin Resistance in a Clinical Vancomycin- and Daptomycin-Resistant Enterococcus faecium Strain. PMID:35801099
Functional Heterogeneity of the Young and Old Duplicate Genes in Tung Tree (Vernicia fordii). PMID:35800614
Identification of Potential miRNA-mRNA Regulatory Network in Denervated Muscular Atrophy by Bioinformatic Analysis. PMID:35800215
Tandem Mass Tag-based proteomics analysis reveals the vital role of inflammation in traumatic brain injury in a mouse model. PMID:35799536
Phylogenies of the 16S rRNA gene and its hypervariable regions lack concordance with core genome phylogenies. PMID:35799218
Biomimetic generation of the strongest known biomaterial found in limpet tooth. PMID:35798724
RNA-Seq and Gene Ontology Analysis Reveal Differences Associated With Low R/FR-Induced Shade Responses in Cultivated Lentil and a Wild Relative. PMID:35795209
Identification of Immune-Related Gene Signature in Stanford Type A Aortic Dissection. PMID:35795203
A statistical, reference-free algorithm subsumes myriad problems in genome science and enables novel discovery. PMID:35794890
Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome. PMID:35793637
Increased CSF-decorin predicts brain pathological changes driven by Alzheimer's Aβ amyloidosis. PMID:35787306
A Comprehensive Pan-Cancer Analysis of the Tumorigenic Role of Matrix Metallopeptidase 7 (MMP7) Across Human Cancers. PMID:35785154
Investigation of the Pharmacological Effect and Mechanism of Jinbei Oral Liquid in the Treatment of Idiopathic Pulmonary Fibrosis Using Network Pharmacology and Experimental Validation. PMID:35784749
Temporal Whole-Transcriptomic Analysis of Characterized In Vitro and Ex Vivo Primary Nasal Epithelia. PMID:35784475
Exposure of Keratinocytes to Candida Albicans in the Context of Atopic Milieu Induces Changes in the Surface Glycosylation Pattern of Small Extracellular Vesicles to Enhance Their Propensity to Interact With Inhibitory Siglec Receptors. PMID:35784319
A consensus view of the proteome of the last universal common ancestor. PMID:35784055
Integrated Metabolomics and Transcriptome Analyses Unveil Pathways Involved in Sugar Content and Rind Color of Two Sugarcane Varieties. PMID:35783968
Genome-scale phylogeography resolves the native population structure of the Asian longhorned beetle, Anoplophora glabripennis (Motschulsky). PMID:35782014
The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors. PMID:35781533
Refining bulk segregant analyses: ontology-mediated discovery of flowering time genes in Brassica oleracea. PMID:35780674
Transcriptomic analysis of starch accumulation patterns in different glutinous sorghum seeds. PMID:35778525
Differential regulation of mRNAs and lncRNAs related to lipid metabolism in Duolang and Small Tail Han sheep. PMID:35778462
The Bioinformatic Study Uncovers Probable Critical Genes Involved in the Pathophysiology of Biliary Atresia. PMID:35774294
Identification of hub genes and regulatory networks in histologically unstable carotid atherosclerotic plaque by bioinformatics analysis. PMID:35773742
N(6)-methyladenosine methylation-regulated polo-like kinase 1 cell cycle homeostasis as a potential target of radiotherapy in pancreatic adenocarcinoma. PMID:35773310
A versatile new tool derived from a bacterial deubiquitylase to detect and purify ubiquitylated substrates and their interacting proteins. PMID:35771886
Icariside II Restores Vascular Smooth Muscle Cell Contractile Phenotype by Enhancing the Focal Adhesion Signaling Pathway in the Rat Vascular Remodeling Model. PMID:35770073
Identification of stress-related genes by co-expression network analysis based on the improved turbot genome. PMID:35768602
GREM1 is required to maintain cellular heterogeneity in pancreatic cancer. PMID:35768509
Genome sequence and pathogenicity of Vibrio vulnificus strain MCCC 1A08743 isolated from contaminated prawns. PMID:35766638
DIP2 is a unique regulator of diacylglycerol lipid homeostasis in eukaryotes. PMID:35766356
Integrated Multi-Omics Analysis Model to Identify Biomarkers Associated With Prognosis of Breast Cancer. PMID:35761863
Inferring functional communities from partially observed biological networks exploiting geometric topology and side information. PMID:35760826
DeepGOZero: improving protein function prediction from sequence and zero-shot learning based on ontology axioms. PMID:35758802
Exploring automatic inconsistency detection for literature-based gene ontology annotation. PMID:35758780
Quality-controlled R-loop meta-analysis reveals the characteristics of R-loop consensus regions. PMID:35758606
GinkgoDB: an ecological genome database for the living fossil, Ginkgo biloba. PMID:35758513
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer's Disease Brain. PMID:35758417
Regional Downregulation of Dopamine Receptor D1 in Bilateral Dorsal Lateral Geniculate Nucleus of Monocular Form-Deprived Amblyopia Models. PMID:35757538
Full-Length Transcriptomics Reveals Complex Molecular Mechanism of Salt Tolerance in Bromus inermis L. PMID:35755679
Orrella daihaiensis sp. nov., a bacterium isolated from Daihai Lake in Inner Mongolia. PMID:35751751
A chromosome-level genome assembly of the orange wheat blossom midge, Sitodiplosis mosellana Géhin (Diptera: Cecidomyiidae) provides insights into the evolution of a detoxification system. PMID:35751604
SAPFIR: A webserver for the identification of alternative protein features. PMID:35751026
Calculating genetic risk for dysfunction in pleiotropic biological processes using whole exome sequencing data. PMID:35751013
Pathway importance by graph convolutional network and Shapley additive explanations in gene expression phenotype of diffuse large B-cell lymphoma. PMID:35749395
Bioinformatics Approach Predicts Candidate Targets for SARS-CoV-2 Infections to COPD Patients. PMID:35747501
Transcriptome and Metabolome Analysis of Upland Cotton (Gossypium hirsutum) Seed Pretreatment with MgSO4 in Response to Salinity Stress. PMID:35743952
Comprehensive RNA Expression Analysis Revealed Biological Functions of Key Gene Sets and Identified Disease-Associated Cell Types Involved in Rat Traumatic Brain Injury. PMID:35743506
Gene Expression Profiling in Abdominal Aortic Aneurysms. PMID:35743331
Dietary Long-Chain n-3 Polyunsaturated Fatty Acid Supplementation Alters Electrophysiological Properties in the Nucleus Accumbens and Emotional Behavior in Naïve and Chronically Stressed Mice. PMID:35743093
Transcriptome Analysis Reveals the Regulatory Networks of Cytokinin in Promoting Floral Feminization in Castanea henryi. PMID:35742833
Identification and Regulatory Network Analysis of Genes Related to Reproductive Performance in the Hypothalamus and Pituitary of Angus Cattle. PMID:35741727
Transcriptomics Integrated with Metabolomics Unveil Carotenoids Accumulation and Correlated Gene Regulation in White and Yellow-Fleshed Turnip (Brassica rapa ssp. rapa). PMID:35741715
The Osmoprotectant Switch of Potassium to Compatible Solutes in an Extremely Halophilic Archaea Halorubrum kocurii 2020YC7. PMID:35741701
A Quantitative Proteomic Approach Explores the Possible Mechanisms by Which the Small Molecule Stemazole Promotes the Survival of Human Neural Stem Cells. PMID:35741576
Cryopreservation of Endangered Ornamental Plants and Fruit Crops from Tropical and Subtropical Regions. PMID:35741368
Predicting prognosis and clinical features of the tumor microenvironment based on ferroptosis score in patients with breast cancer. PMID:35739315
PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages. PMID:35738799
Transcriptome analysis reveals regulation mechanism of methyl jasmonate-induced terpenes biosynthesis in Curcuma wenyujin. PMID:35737688
Transcriptomics and Metabolomics Analyses Reveal High Induction of the Phenolamide Pathway in Tomato Plants Attacked by the Leafminer Tuta absoluta. PMID:35736416
Genome Analysis of a Novel Polysaccharide-Degrading Bacterium Paenibacillus algicola and Determination of Alginate Lyases. PMID:35736191
Pan-Genomes Provide Insights into the Genetic Basis of Auricularia heimuer Domestication. PMID:35736064
Exploration of the Nurse Shark (Ginglymostoma cirratum) Plasma Immunoproteome Using High-Resolution LC-MS/MS. PMID:35734164
The chromosome-level genome for Toxicodendron vernicifluum provides crucial insights into Anacardiaceae evolution and urushiol biosynthesis. PMID:35733792
Antennal transcriptome analysis of olfactory genes and tissue expression profiling of odorant binding proteins in Semanotus bifasciatus (cerambycidae: coleoptera). PMID:35733103
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy. PMID:35732739
Integrative transcriptome-wide analysis of atopic dermatitis for drug repositioning. PMID:35729261
Metatranscriptomics captures dynamic shifts in mycorrhizal coordination in boreal forests. PMID:35727987
Systematic identification of molecular mediators of interspecies sensing in a community of two frequently coinfecting bacterial pathogens. PMID:35727825
Detecting Structural Variants and Associated Gene Presence-Absence Variation Phenomena in the Genomes of Marine Organisms. PMID:35727540
Increased expression of tribbles homolog 3 predicts poor prognosis and correlates with tumor immunity in clear cell renal cell carcinoma: a bioinformatics study. PMID:35726370
Integrated Bioinformatics Analysis for Identifying the Significant Genes as Poor Prognostic Markers in Gastric Adenocarcinoma. PMID:35726219
Deep embeddings to comprehend and visualize microbiome protein space. PMID:35725732
Human follicular mites: Ectoparasites becoming symbionts. PMID:35724423
Developing Biliary Atresia-like Model by Treating Human Liver Organoids with Polyinosinic:Polycytidylic Acid (Poly (I:C)). PMID:35723330
Integrated Analysis of Glutathione Metabolic Pathway in Pancreatic Cancer. PMID:35721499
Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis. PMID:35720265
Integrating Network Pharmacology and Experimental Validation to Explore the Key Mechanism of Gubitong Recipe in the Treatment of Osteoarthritis. PMID:35720033
A Robust Immuno-Prognostic Model of Non-Muscle-Invasive Bladder Cancer Indicates Dynamic Interaction in Tumor Immune Microenvironment Contributes to Cancer Progression. PMID:35719408
Identification of potential gene markers in gestational diabetes mellitus. PMID:35718998
Longitudinal plasma proteomic profiling of patients with non-small cell lung cancer undergoing immune checkpoint blockade. PMID:35718373
The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells. PMID:35717336
Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids. PMID:35717025
Proteomics Reveals Long-Term Alterations in Signaling and Metabolic Pathways Following Both Myocardial Infarction and Chemically Induced Denervation. PMID:35716295
Ascorbate peroxidase-mediated in situ labelling of proteins in secreted exosomes. PMID:35716063
Protein Subcellular Localization Prediction Model Based on Graph Convolutional Network. PMID:35713780
Molecular Signatures of Response to Mecasermin in Children With Rett Syndrome. PMID:35712450
Identification of Core Genes and Screening of Potential Targets in Intervertebral Disc Degeneration Using Integrated Bioinformatics Analysis. PMID:35711934
SFARI genes and where to find them; modelling Autism Spectrum Disorder specific gene expression dysregulation with RNA-seq data. PMID:35710789
A hexa-species transcriptome atlas of mammalian embryogenesis delineates metabolic regulation across three different implantation modes. PMID:35710749
Genome-wide association study of musical beat synchronization demonstrates high polygenicity. PMID:35710621
Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform. PMID:35710324
CaveCrawler: an interactive analysis suite for cavefish bioinformatics. PMID:35708643
Computation-Based Discovery of Potential Targets for Rheumatoid Arthritis and Related Molecular Screening and Mechanism Analysis of Traditional Chinese Medicine. PMID:35707715
An Insight Into Pentatricopeptide-Mediated Chloroplast Necrosis via microRNA395a During Rhizoctonia solani Infection. PMID:35706449
Analysis and pharmacological modulation of senescence in human epithelial stem cells. PMID:35706382
Genome-wide translation control analysis of developing human neurons. PMID:35706057
Proteome analysis of urinary biomarkers in a cigarette smoke-induced COPD rat model. PMID:35705945
Combined transcriptome and metabolome analysis of Nerium indicum L. elaborates the key pathways that are activated in response to witches' broom disease. PMID:35701735
Anticancer effects of herbal medicines in pancreatic ductal adenocarcinoma through modulation of steroid hormone response proteins. PMID:35701649
Tree House Explorer: A Novel Genome Browser for Phylogenomics. PMID:35700217
The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib. PMID:35695059
The fourth scientific discovery paradigm for precision medicine and healthcare: Challenges ahead. PMID:35694156
Trained Immunity in Perivascular Adipose Tissue of Abdominal Aortic Aneurysm-A Novel Concept for a Still Elusive Disease. PMID:35693946
Identification of Hub Genes in Colorectal Adenocarcinoma by Integrated Bioinformatics. PMID:35693937
Identification of Four Novel Prognostic Biomarkers and Construction of Two Nomograms in Adrenocortical Carcinoma: A Multi-Omics Data Study via Bioinformatics and Machine Learning Methods. PMID:35693556
Identification of Potential Biomarkers for Ryanodine Receptor 1 (RYR1) Mutation-Associated Myopathies Using Bioinformatics Approach. PMID:35692882
Circulating Exosomal miR-144-3p from Crohn's Disease Patients Inhibits Human Umbilical Vein Endothelial Cell Function by Targeting FN1. PMID:35692876
Screening the Potential Biomarkers of COVID-19-Related Thrombosis Through Bioinformatics Analysis. PMID:35692833
Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis. PMID:35692536
Overexpression of lncRNA-Gm2044 in spermatogonia impairs spermatogenesis in partial seminiferous tubules. PMID:35691049
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. PMID:35690868
Omics-based integrated analysis identified IKZF2 as a biomarker associated with lupus nephritis. PMID:35688845
Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery. PMID:35686059
Analysis of the landscape of human enhancer sequences in biological databases. PMID:35685360
Bioinformatics Analysis for Identifying Differentially Expressed MicroRNAs Derived from Plasma Exosomes Associated with Radiotherapy Resistance in Non-Small-Cell Lung Cancer. PMID:35685351
The dynamic cellular and molecular features during the development of radiation proctitis revealed by transcriptomic profiling in mice. PMID:35681125
Ptpn1 deletion protects oval cells against lipoapoptosis by favoring lipid droplet formation and dynamics. PMID:35681014
Translocating proteins compartment-specifically alter the fate of epithelial-mesenchymal transition in a compartmentalized Boolean network model. PMID:35680961
A transcriptomic atlas underlying developmental plasticity of seasonal forms of Bicyclus anynana butterflies. PMID:35679434
Effects of Lightning on Rhizosphere Soil Properties, Bacterial Communities, and Active Components of Camellia sinensis var. assamica. PMID:35677900
Interaction Between Cecal Metabolites and Liver Lipid Metabolism Pathways During Induced Molting in Laying Hens. PMID:35677092
Comparative transcriptome analysis reveals a rapid response to phosphorus deficiency in a phosphorus-efficient rice genotype. PMID:35676419
Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19. PMID:35676404
3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors. PMID:35676403
Integrative PheWAS analysis in risk categorization of major depressive disorder and identifying their associations with genetic variants using a latent topic model approach. PMID:35676267
Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation. PMID:35676234
Comparative genomics reveals low levels of inter- and intraspecies diversity in the causal agents of dwarf and common bunt of wheat and hint at conspecificity of Tilletia caries and T. laevis. PMID:35672841
Digital quantification of p16-positive foci in fibrotic interstitial lung disease is associated with a phenotype of idiopathic pulmonary fibrosis with reduced survival. PMID:35672770
Gene network analysis reveals candidate genes related with the hair follicle development in sheep. PMID:35672687
Comprehensive analysis of lncRNA-miRNA-mRNA networks during osteogenic differentiation of bone marrow mesenchymal stem cells. PMID:35672672
Network assisted analysis of de novo variants using protein-protein interaction information identified 46 candidate genes for congenital heart disease. PMID:35671298
HemI 2.0: an online service for heatmap illustration. PMID:35670661
In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos (Anser cygnoides). PMID:35669574
Identification of the Active Compound of Liu Wei Di Huang Wan for Treatment of Gestational Diabetes Mellitus via Network Pharmacology and Molecular Docking. PMID:35669396
Digital Cell Atlas of Mouse Uterus: From Regenerative Stage to Maturational Stage. PMID:35669188
Chromosome-Scale, Haplotype-Resolved Genome Assembly of Non-Sex-Reversal Females of Swamp Eel Using High-Fidelity Long Reads and Hi-C Data. PMID:35669182
The Development of Mechanical Allodynia in Diabetic Rats Revealed by Single-Cell RNA-Seq. PMID:35668789
Circulating microRNAs (miR-16, miR-22, miR-122) expression and early diagnosis of hepatocellular carcinoma. PMID:35666610
The impact of genetic modifiers on variation in germline mutation rates within and among human populations. PMID:35666194
Quantifying concordant genetic effects of de novo mutations on multiple disorders. PMID:35666111
Incubation of canine dermal fibroblasts with serum from dogs with atopic dermatitis activates extracellular matrix signalling and represses oxidative phosphorylation. PMID:35665445
Full-Length Transcriptional Analysis of the Same Soybean Genotype With Compatible and Incompatible Reactions to Heterodera glycines Reveals Nematode Infection Activating Plant Defense Response. PMID:35665156
Complete Genome Analysis of Highly Pathogenic Non-O1/O139 Vibrio cholerae Isolated From Macrobrachium rosenbergii Reveals Pathogenicity and Antibiotic Resistance-Related Genes. PMID:35664858
The interplay between lncRNAs, RNA-binding proteins and viral genome during SARS-CoV-2 infection reveals strong connections with regulatory events involved in RNA metabolism and immune response. PMID:35664076
Evaluating the Immune Response in Treatment-Naive Hospitalised Patients With Influenza and COVID-19. PMID:35663963
Serum miRNA Profile in Diabetic Patients With Ischemic Heart Disease as a Promising Non-Invasive Biomarker. PMID:35663309
miRNA-432 and SLC38A1 as Predictors of Hepatocellular Carcinoma Complicated with Alcoholic Steatohepatitis. PMID:35663198
Proteomic-based evidence for adult neurogenesis in birds and mammals as indicated from cerebrospinal fluid. PMID:35662184
Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome. PMID:35661148
De novo reconstruction of cell interaction landscapes from single-cell spatial transcriptome data with DeepLinc. PMID:35659722
Simulating the restoration of normal gene expression from different thyroid cancer stages using deep learning. PMID:35659616
Integrated proteogenomic characterization of urothelial carcinoma of the bladder. PMID:35659036
Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions. PMID:35658533
Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology. PMID:35657417
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma. PMID:35656882
Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model. PMID:35655589
Spatial Mapping of Plant N-Glycosylation Cellular Heterogeneity Inside Soybean Root Nodules Provided Insights Into Legume-Rhizobia Symbiosis. PMID:35651768
Characterisation of a nucleo-adhesome. PMID:35650196
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases. PMID:35649411
RSK1 promotes mammalian axon regeneration by inducing the synthesis of regeneration-related proteins. PMID:35648763
Dynamic Transcriptome Profiling Reveals LncRNA-Centred Regulatory Networks in the Modulation of Pluripotency. PMID:35646895
Pan-Cancer Single-Cell Analysis Reveals the Core Factors and Pathway in Specific Cancer Stem Cells of Upper Gastrointestinal Cancer. PMID:35646860
Reclassification of Hepatocellular Cancer With Neural-Related Genes. PMID:35646712
Identification of a Cancer Stem Cells Signature of Head and Neck Squamous Cell Carcinoma. PMID:35646104
Identification of Context-Specific Fitness Genes Associated With Metabolic Rearrangements for Prognosis and Potential Treatment Targets for Liver Cancer. PMID:35646101
An equivalence test between features lists, based on the Sorensen-Dice index and the joint frequencies of GO term enrichment. PMID:35641928
Mapping the cardiac vascular niche in heart failure. PMID:35641541
Identification of Ferroptosis-Related Hub Genes and Their Association with Immune Infiltration in Chronic Obstructive Pulmonary Disease by Bioinformatics Analysis. PMID:35637927
Chemical reaction network knowledge graphs: the OntoRXN ontology. PMID:35637523
A tensor-based bi-random walks model for protein function prediction. PMID:35637427
Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations. PMID:35637371
FAM83A antisense RNA 1 (FAM83A-AS1) silencing impairs cell proliferation and induces autophagy via MET-AMPKɑ signaling in lung adenocarcinoma. PMID:35635086
Distinct Injury Responsive Regulatory T Cells Identified by Multi-Dimensional Phenotyping. PMID:35634302
Low Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Molecular Changes That Occur to Repair Radiation Damage and Gene Transcripts That May Be Involved in Establishing Disease in Mice Post-Irradiation. PMID:35634275
High Expression of HERV-K (HML-2) Might Stimulate Interferon in COVID-19 Patients. PMID:35632738
Flavivirus Capsid Proteins Inhibit the Interferon Response. PMID:35632712
Intense Innate Immune Responses and Severe Metabolic Disorders in Chicken Embryonic Visceral Tissues Caused by Infection with Highly Virulent Newcastle Disease Virus Compared to the Avirulent Virus: A Bioinformatics Analysis. PMID:35632651
Transcriptomics Integrated with Metabolomics Reveals 2-Methoxy-1, 4-Naphthoquinone-Based Carbon Dots Induced Molecular Shifts in Penicillium italicum. PMID:35628676
Analysis of Huntington's Disease Modifiers Using the Hyperbolic Mapping of the Protein Interaction Network. PMID:35628660
The Role of Transposable Elements of the Human Genome in Neuronal Function and Pathology. PMID:35628657
Dynamic Changes in Ascorbic Acid Content during Fruit Development and Ripening of Actinidia latifolia (an Ascorbate-Rich Fruit Crop) and the Associated Molecular Mechanisms. PMID:35628618
Epigenetic Silencing of PTEN and Epi-Transcriptional Silencing of MDM2 Underlied Progression to Secondary Acute Myeloid Leukemia in Myelodysplastic Syndrome Treated with Hypomethylating Agents. PMID:35628480
ASC-J9 Blocks Cell Proliferation and Extracellular Matrix Production of Keloid Fibroblasts through Inhibiting STAT3 Signaling. PMID:35628356
Identification and Transcriptome Analysis of Genes Related to Membrane Lipid Regulation in Sweet Sorghum under Salt Stress. PMID:35628281
Impact of Environmentally Relevant Concentrations of Bisphenol A (BPA) on the Gene Expression Profile in an In Vitro Model of the Normal Human Ovary. PMID:35628146
Inferring Potential Cancer Driving Synonymous Variants. PMID:35627162
CAPTURE of the Human U2 snRNA Genes Expands the Repertoire of Associated Factors. PMID:35625631
Comparative Proteomic Analysis Reveals the Effect of Selenoprotein W Deficiency on Oligodendrogenesis in Fear Memory. PMID:35624863
Association of a Novel DOCK2 Mutation-Related Gene Signature With Immune in Hepatocellular Carcinoma. PMID:35620462
Single-Cell RNA Sequencing Profiles Identify Important Pathophysiologic Factors in the Progression of Diabetic Nephropathy. PMID:35620059
CRISPR Library Screening in Cultured Cardiomyocytes. PMID:35618895
Novel reusable animal model for comparative evaluation of in vivo growth and protein-expression of Escherichia coli O157 strains in the bovine rumen. PMID:35617366
Bacterial Infection Induces Ultrastructural and Transcriptional Changes in the King Oyster Mushroom (Pleurotus eryngii). PMID:35616396
Investigating the Molecular Mechanism of Quercetin Protecting against Podocyte Injury to Attenuate Diabetic Nephropathy through Network Pharmacology, MicroarrayData Analysis, and Molecular Docking. PMID:35615688
Identification of Differential Genes of DNA Methylation Associated With Alzheimer's Disease Based on Integrated Bioinformatics and Its Diagnostic Significance. PMID:35615586
Proteome-wide prediction and analysis of the Cryptosporidium parvum protein-protein interaction network through integrative methods. PMID:35615014
Effects of Chang-Kang-Fang Formula on the Microbiota-Gut-Brain Axis in Rats With Irritable Bowel Syndrome. PMID:35614949
Single-molecule long-read sequencing analysis improves genome annotation and sheds new light on the transcripts and splice isoforms of Zoysia japonica. PMID:35614434
Discovery of bioactive microbial gene products in inflammatory bowel disease. PMID:35614211
An Myh11 single lysine deletion causes aortic dissection by reducing aortic structural integrity and contractility. PMID:35614093
Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming. PMID:35614060
7-Methoxyisoflavone ameliorates atopic dermatitis symptoms by regulating multiple signaling pathways and reducing chemokine production. PMID:35610286
R-loop Mapping and Characterization During Drosophila Embryogenesis Reveals Developmental Plasticity in R-loop Signatures. PMID:35609632
Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying. PMID:35606346
Exploiting plant transcriptomic databases: Resources, tools, and approaches. PMID:35605200
The Translational Landscape of SARS-CoV-2-infected Cells Reveals Suppression of Innate Immune Genes. PMID:35604092
Pollock: fishing for cell states. PMID:35603231
Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia. PMID:35602885
RNA-seq and Network Analysis Reveal Unique Chemokine Activity Signatures in the Synovial Tissue of Patients With Rheumatoid Arthritis. PMID:35602512
CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling. PMID:35601606
A Four-Gene Prognostic Signature Based on the TEAD4 Differential Expression Predicts Overall Survival and Immune Microenvironment Estimation in Lung Adenocarcinoma. PMID:35600867
A Protocol for the Cryopreservation of Human Intestinal Mucosal Biopsies Compatible With Single-Cell Transcriptomics and Ex Vivo Studies. PMID:35600311
Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation. PMID:35600072
Biotechnological Combination for Co-contaminated Soil Remediation: Focus on Tripartite "Meta-Enzymatic" Activity. PMID:35599908
Dataset of De Novo hybrid berry transcriptome profiling and characterization of Piper species (Piper nigrum and Piper longum) using Illumina and Nanopore sequencing. PMID:35599816
Combined use of specific length amplified fragment sequencing (SLAF-seq) and bulked segregant analysis (BSA) for rapid identification of genes influencing fiber content of hemp (Cannabis sativa L.). PMID:35596150
The ceRNA Crosstalk between mRNAs and lncRNAs in Diabetes Myocardial Infarction. PMID:35592708
Development of a Bile Acid-Related Gene Signature for Predicting Survival in Patients with Hepatocellular Carcinoma. PMID:35592684
Patterns of genomic divergence in sympatric and allopatric speciation of three Mihoutao (Actinidia) species. PMID:35591930
Identifying Alzheimer's genes via brain transcriptome mapping. PMID:35590321
Complete genome sequence of Pseudomonas stutzeri S116 owning bifunctional catalysis provides insights into affecting performance of microbial fuel cells. PMID:35590268
Genome mining reveals polysaccharide-degrading potential and new antimicrobial gene clusters of novel intestinal bacterium Paenibacillus jilinensis sp. nov. PMID:35590262
Oceanisphaera pacifica sp. nov., isolated from the intestine of Trichiurus japonicus. PMID:35590019
Exploration of the Potential Mechanism of the Common Differentially Expressed Genes in Psoriasis and Atopic Dermatitis. PMID:35586812
Physiological Effects and Transcriptomic Analysis of sbGnRH on the Liver in Pompano (Trachinotus ovatus). PMID:35586618
CBEA: Competitive balances for taxonomic enrichment analysis. PMID:35584140
Construction and comprehensive analysis of a lncRNA-mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development. PMID:35583799
Identification of LINE retrotransposons and long non-coding RNAs expressed in the octopus brain. PMID:35581640
Identification of combined biomarkers for predicting the risk of osteoporosis using machine learning. PMID:35580864
GenePlexus: a web-server for gene discovery using network-based machine learning. PMID:35580053
Human phospho-signaling networks of SARS-CoV-2 infection are rewired by population genetic variants. PMID:35579274
Immune-Related Biomarkers Associated with Lung Metastasis from the Colorectal Cancer Microenvironment. PMID:35576491
A molecular view of amyotrophic lateral sclerosis through the lens of interaction network modules. PMID:35576218
Machine learning: its challenges and opportunities in plant system biology. PMID:35575915
Transcription elongation is finely tuned by dozens of regulatory factors. PMID:35575476
Recognition of Gonadal Development in Eriocheir sinensis Based on the Impulse of Love at First Sight. PMID:35574457
A Prognostic Gene Signature for Hepatocellular Carcinoma. PMID:35574316
CsbZIP2-miR9748-CsNPF4.4 Module Mediates High Temperature Tolerance of Cucumber Through Jasmonic Acid Pathway. PMID:35574100
Integrative clustering methods for multi-omics data. PMID:35573155
lncRNA-mRNA Expression Patterns in Invasive Pituitary Adenomas: A Microarray Analysis. PMID:35572729
Mitochondrial 1555 G>A variant as a potential risk factor for childhood glioblastoma. PMID:35571988
Identification of genes and pathways leading to poor prognosis of non-small cell lung cancer using integrated bioinformatics analysis. PMID:35571642
Genome-Wide Identification of Associations of Circulating Molecules With Spontaneous Coronary Artery Dissection and Aortic Aneurysm and Dissection. PMID:35571188
Natural selenium stress influences the changes of antibiotic resistome in seleniferous forest soils. PMID:35570296
Diagnosis of pulmonary tuberculosis via identification of core genes and pathways utilizing blood transcriptional signatures: a multicohort analysis. PMID:35568895
Chemical Diversity and Potential Target Network of Woody Peony Flower Essential Oil from Eleven Representative Cultivars (Paeonia × suffruticosa Andr.). PMID:35566179
The Mantle Transcriptome of Chamelea gallina (Mollusca: Bivalvia) and Shell Biomineralization. PMID:35565623
Identification of Genes Related to Squab Muscle Growth and Lipid Metabolism from Transcriptome Profiles of Breast Muscle and Liver in Domestic Pigeon (Columba livia). PMID:35565488
Cancer Metabolic Subtypes and Their Association with Molecular and Clinical Features. PMID:35565274
Bone Progenitors Pull the Strings on the Early Metabolic Rewiring Occurring in Prostate Cancer Cells. PMID:35565211
Transcriptome Analysis of the Cf-13-Mediated Hypersensitive Response of Tomato to Cladosporium fulvum Infection. PMID:35563232
Targeting Cell Death Mechanism Specifically in Triple Negative Breast Cancer Cell Lines. PMID:35563174
Insights into the Molecular Regulation of Lignin Content in Triploid Poplar Leaves. PMID:35562994
Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways. PMID:35562349
Nuclear oligo hashing improves differential analysis of single-cell RNA-seq. PMID:35562344
Design and application of a knowledge network for automatic prioritization of drug mechanisms. PMID:35561182
Annotating regulatory elements by heterogeneous network embedding. PMID:35561169
CrowdGO: Machine learning and semantic similarity guided consensus Gene Ontology annotation. PMID:35560159
Shared genetic loci between depression and cardiometabolic traits. PMID:35560157
Identification of Potential Diagnoses Based on Immune Infiltration and Autophagy Characteristics in Major Depressive Disorder. PMID:35559009
A Community-Driven, Openly Accessible Molecular Pathway Integrating Knowledge on Malignant Pleural Mesothelioma. PMID:35558518
Genome-Wide Association Study and Genomic Selection for Proteinogenic Methionine in Soybean Seeds. PMID:35557723
Exome sequencing of hepatocellular carcinoma in lemurs identifies potential cancer drivers: A pilot study. PMID:35557512
Inositol polyphosphate multikinase physically binds to the SWI/SNF complex and modulates BRG1 occupancy in mouse embryonic stem cells. PMID:35551737
The Immunometabolic Atlas: A tool for design and interpretation of metabolomics studies in immunology. PMID:35550647
Enhancing Data Integration, Interoperability, and Reuse to Address Complex and Emerging Environmental Health Problems. PMID:35549252
An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-κB/TNF-α Signaling in Macrophages. PMID:35548340
Genome-Wide Identification and Expression Profiling of KCS Gene Family in Passion Fruit (Passiflora edulis) Under Fusarium kyushuense and Drought Stress Conditions. PMID:35548275
Integrative analysis of clinical and epigenetic biomarkers of mortality. PMID:35546478
LncMIR181A1HG is a novel chromatin-bound epigenetic suppressor of early stage osteogenic lineage commitment. PMID:35546168
Degron masking outlines degronons, co-degrading functional modules in the proteome. PMID:35545699
A natural mutator allele shapes mutation spectrum variation in mice. PMID:35545679
H3K27 methylation regulates the fate of two cell lineages in male gametophytes. PMID:35543471
Text mining for identification of biological entities related to antibiotic resistant organisms. PMID:35539017
Transcriptomic and metabolomic landscape of quinoa during seed germination. PMID:35538406
Acetylome analysis of acetylation providing new insight into sclerotial generation in medicinal fungus Polyporus umbellatus. PMID:35538155
Statin therapy inhibits fatty acid synthase via dynamic protein modifications. PMID:35538051
DEPCOD: a tool to detect and visualize co-evolution of protein domains. PMID:35536332
SubcellulaRVis: a web-based tool to simplify and visualise subcellular compartment enrichment. PMID:35536291
deepSimDEF: deep neural embeddings of gene products and Gene Ontology terms for functional analysis of genes. PMID:35536192
Enrichment analysis on regulatory subspaces: A novel direction for the superior description of cellular responses to SARS-CoV-2. PMID:35533463
Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology. PMID:35531351
A recent burst of gene duplications in Triticeae. PMID:35529951
Selection Signature Analyses Revealed Genes Associated With Adaptation, Production, and Reproduction in Selected Goat Breeds in Kenya. PMID:35528543
Screening of molecular targets and construction of a ceRNA network for oxaliplatin resistance in colorectal cancer. PMID:35527927
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis. PMID:35525247
Whole genome sequencing and analysis of fenvalerate degrading bacteria Citrobacter freundii CD-9. PMID:35523901
A Bayesian network structure learning approach to identify genes associated with stress in spleens of chickens. PMID:35523843
Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum. PMID:35523767
Wnt11 acts on dermomyotome cells to guide epaxial myotome morphogenesis. PMID:35522214
Identification and characterization of differentially expressed miRNAs in HepG2 cells under normoxic and hypoxic conditions. PMID:35516357
Full-Length Transcriptome Sequencing Reveals Tissue-Specific Gene Expression Profile of Mangrove Clam Geloina erosa. PMID:35514334
Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii. PMID:35513725
PRD-Class Homeobox Genes in Bovine Early Embryos: Function, Evolution, and Overlapping Roles. PMID:35512670
A targeted approach to investigating immune genes of an iconic Australian marsupial. PMID:35510793
Signatures of selection in core and accessory genomes indicate different ecological drivers of diversification among Bacillus cereus clades. PMID:35510788
Mechanism of Ba Zhen Tang Delaying Skin Photoaging Based on Network Pharmacology and Molecular Docking. PMID:35510223
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice. PMID:35509309
Two conserved amino acids differentiate the biology of high-risk and low-risk HPV E5 proteins. PMID:35509176
Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle. PMID:35508966
Survival-related genes are diversified across cancers but generally enriched in cancer hallmark pathways. PMID:35508961
IMEx Databases: Displaying Molecular Interactions into a Single, Standards-Compliant Dataset. PMID:35507258
Roseococcus pinisoli sp. nov., lacking pufL and pufM bacteriochlorophyll a: synthesizing genes. PMID:35507236
High MICAL-L2 expression and its role in the prognosis of colon adenocarcinoma. PMID:35501725
Evidence of multiple genome duplication events in Mytilus evolution. PMID:35501689
Mapping the epithelial-immune cell interactome upon infection in the gut and the upper airways. PMID:35501398
Identification of HMOX1 as a Critical Ferroptosis-Related Gene in Atherosclerosis. PMID:35498043
Faster Growth Enhances Low Carbon Fuel and Chemical Production Through Gas Fermentation. PMID:35497340
A new ChEMBL dataset for the similarity-based target fishing engine FastTargetPred: Annotation of an exhaustive list of linear tetrapeptides. PMID:35496477
Identification of NFASC and CHL1 as Two Novel Hub Genes in Endometriosis Using Integrated Bioinformatic Analysis and Experimental Verification. PMID:35496348
Fluvalinate-Induced Changes in MicroRNA Expression Profile of Apis mellifera ligustica Brain Tissue. PMID:35495168
m6A-mediated modulation coupled with transcriptional regulation shapes long noncoding RNA repertoire of the cGAS-STING signaling. PMID:35495108
A collaborative semantic-based provenance management platform for reproducibility. PMID:35494870
From Beginning to End: Expanding the SERINC3 Interactome Through an in silico Analysis. PMID:35494555
Single-Cell RNA Sequencing of Metastatic Testicular Seminoma Reveals the Cellular and Molecular Characteristics of Metastatic Cell Lineage. PMID:35494058
Systematic molecular analysis of the human secretome and membrane proteome in gastrointestinal adenocarcinomas. PMID:35488454
An integrated network representation of multiple cancer-specific data for graph-based machine learning. PMID:35487924
The clinical value of miRNA-21 in cervical cancer: A comprehensive investigation based on microarray datasets. PMID:35486636
Genome annotation of Caenorhabditis briggsae by TEC-RED identifies new exons, paralogs, and conserved and novel operons. PMID:35485953
Metagenome-assembled genomes of phytoplankton microbiomes from the Arctic and Atlantic Oceans. PMID:35484634
Transcriptome and metabolome analyses reveal new insights into chlorophyll, photosynthesis, metal ion and phenylpropanoids related pathways during sugarcane ratoon chlorosis. PMID:35484490
Identification of replication fork-associated proteins in Drosophila embryos and cultured cells using iPOND coupled to quantitative mass spectrometry. PMID:35484306
An Arabidopsis mutant deficient in phosphatidylinositol-4-phosphate kinases ß1 and ß2 displays altered auxin-related responses in roots. PMID:35484296
Protein N-glycosylation aberrations and glycoproteomic network alterations in osteoarthritis and osteoarthritis with type 2 diabetes. PMID:35484284
The genome of hibiscus hamabo reveals its adaptation to saline and waterlogged habitat. PMID:35480957
m6A Regulator-Mediated RNA Methylation Modification Patterns are Involved in the Pathogenesis and Immune Microenvironment of Depression. PMID:35480327
Characterization of differential gene expression of broiler chicken to thermal stress in discrete developmental stages. PMID:35479510
Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening. PMID:35479399
Integrated analysis of transcriptomic data reveals the platelet response in COVID-19 disease. PMID:35477940
Proteomic networks associated with tumor-educated macrophage polarization and cytotoxicity potentiated by heat-killed tuberculosis. PMID:35477732
LM-GVP: an extensible sequence and structure informed deep learning framework for protein property prediction. PMID:35477726
Lupus Susceptibility Loci Predispose Mice to Clonal Lymphocytic Responses and Myeloid Expansion. PMID:35477687
The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses. PMID:35475759
Integrative analysis of TCGA data identifies miRNAs as drug-specific survival biomarkers. PMID:35474090
Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data. PMID:35473573
Differential gene expression in nasal airway epithelium from overweight or obese youth with asthma. PMID:35470932
An extraction from Trametes robiniophila Murr. (Huaier) inhibits non-small cell lung cancer proliferation via targeting to epidermal growth factor receptor. PMID:35470770
Daily running enhances molecular and physiological circadian rhythms in skeletal muscle. PMID:35470095
Deletion and tandem duplications of biosynthetic genes drive the diversity of triterpenoids in Aralia elata. PMID:35468919
Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway. PMID:35468773
Pseudomonas aeruginosa Initiates a Rapid and Specific Transcriptional Response during Surface Attachment. PMID:35467391
Chemical-induced gene expression ranking and its application to pancreatic cancer drug repurposing. PMID:35465231
Co-expression Mechanism Analysis of Different Tachyplesin I-Resistant Strains in Pseudomonas aeruginosa Based on Transcriptome Sequencing. PMID:35464984
A Chromosome-Level Reference Genome of Chinese Balloon Flower (Platycodon grandiflorus). PMID:35464833
A Bayesian framework to integrate multi-level genome-scale data for Autism risk gene prioritization. PMID:35459094
Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer's Disease Patients. PMID:35456941
Ovarian Transcriptomic Analysis of Ninghai Indigenous Chickens at Different Egg-Laying Periods. PMID:35456401
Treatment with Ad5-Porcine Interferon-α Attenuates Ebolavirus Disease in Pigs. PMID:35456124
Ontologies and Knowledge Graphs in Oncology Research. PMID:35454813
Proteomic Response of Bacillus subtilis Spores under High Pressure Combined with Moderate Temperature and Random Peptide Mixture LK Treatment. PMID:35454710
Sphingolipid Metabolism as a New Predictive Target Correlated with Aging and AD: A Transcriptomic Analysis. PMID:35454332
Identification of Intrinsically Disordered Proteins and Regions in a Non-Model Insect Species Ostrinia nubilalis (Hbn.). PMID:35454181
Testicular "Inherited Metabolic Memory" of Ancestral High-Fat Diet Is Associated with Sperm sncRNA Content. PMID:35453658
Coexpression reveals conserved gene programs that co-vary with cell type across kingdoms. PMID:35451481
Antifungal Effect of Copper Nanoparticles against Fusarium kuroshium, an Obligate Symbiont of Euwallacea kuroshio Ambrosia Beetle. PMID:35448578
Pan-Genomic and Transcriptomic Analyses of Marine Pseudoalteromonas agarivorans Hao 2018 Revealed Its Genomic and Metabolic Features. PMID:35447921
Transcriptional Regulation of Reproductive Diapause in the Convergent Lady Beetle, Hippodamia convergens. PMID:35447785
Impact of medication on blood transcriptome reveals off-target regulations of beta-blockers. PMID:35446883
Transcriptome Analysis of Otodectes cynotis in Different Developmental Stages. PMID:35444625
Comparative Genomics Assisted Functional Characterization of Rahnella aceris ZF458 as a Novel Plant Growth Promoting Rhizobacterium. PMID:35444623
Genomics, convergent neuroscience and progress in understanding autism spectrum disorder. PMID:35440779
Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures. PMID:35440634
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability. PMID:35440568
Integrative analysis of mutated genes and mutational processes reveals novel mutational biomarkers in colorectal cancer. PMID:35439935
Improving ovarian cancer treatment decision using a novel risk predictive tool. PMID:35439731
Construction of a circRNA-Mediated ceRNA Network Reveals Novel Biomarkers for Aortic Dissection. PMID:35437351
Integrative analysis of key microRNA-mRNA complexes and pathways in aortic aneurysm. PMID:35433971
Up-to-Date Pathologic Classification and Molecular Characteristics of Intrahepatic Cholangiocarcinoma. PMID:35433771
Integrative Analyses of Circulating mRNA and lncRNA Expression Profile in Plasma of Lung Cancer Patients. PMID:35433477
Identification and Verification of Potential Hub Genes in Amphetamine-Type Stimulant (ATS) and Opioid Dependence by Bioinformatic Analysis. PMID:35432486
Integrative Analysis of Biomarkers and Mechanisms in Adamantinomatous Craniopharyngioma. PMID:35432485
Comparative Transcriptome Analysis Provides Insight into Spatio-Temporal Expression Characteristics and Genetic Regulatory Network in Postnatal Developing Subcutaneous and Visceral Fat of Bama Pig. PMID:35432468
The LINC00452/miR-204/CHST4 Axis Regulating Thymic Tregs Might Be Involved in the Progression of Thymoma-Associated Myasthenia Gravis. PMID:35432149
Identification and Validation of Hub Genes with Poor Prognosis in Hepatocellular Carcinoma by Integrated Bioinformatical Analysis. PMID:35431572
Autophagy Induced by BCL2-Related ceRNA Network Participates in the Occurrence of COPD. PMID:35431545
Combined Hypothesis Testing on Graphs with Applications to Gene Set Enrichment Analysis. PMID:35431372
Identification and characterization of circular RNAs in Longissimus dorsi muscle tissue from two goat breeds using RNA-Seq. PMID:35429278
Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells. PMID:35427494
Standardized genome-wide function prediction enables comparative functional genomics: a new application area for Gene Ontologies in plants. PMID:35426911
Association of Circulating Cathepsin B Levels With Blood Pressure and Aortic Dilation. PMID:35425820
Beneficial roles of the AhR ligand FICZ on the regenerative potentials of BMSCs and primed cartilage templates. PMID:35425032
Network pharmacology-based analysis for unraveling potential cancer-related molecular targets of Egyptian propolis phytoconstituents accompanied with molecular docking and in vitro studies. PMID:35423607
Identification and Validation of Immune Cells and Hub Genes in Gastric Cancer Microenvironment. PMID:35422890
Isolation of Anaerobic Bromate-Reducing Bacteria Using Different Carbon Sources and Transcriptomic Insights From Klebsiella variicola Glu3. PMID:35422780
Bioinformatics Analysis Identified the Hub Genes, mRNA-miRNA-lncRNA Axis, and Signaling Pathways Involved in Rheumatoid Arthritis Pathogenesis. PMID:35422654
Investigating the disordered regions (MoRFs, SLiMs and LCRs) and functions of mimicry proteins/peptides in silico. PMID:35421114
Vero cells gain renal tubule markers in low-calcium and magnesium chemically defined media. PMID:35418617
Integration of Aspergillus niger transcriptomic profile with metabolic model identifies potential targets to optimise citric acid production from lignocellulosic hydrolysate. PMID:35418297
Analysis of human brain tissue derived from DBS surgery. PMID:35418104
A systematic review and functional bioinformatics analysis of genes associated with Crohn's disease identify more than 120 related genes. PMID:35418025
Progenitor potential of lung epithelial organoid cells in a transplantation model. PMID:35417699
Semantic clustering analysis of E3-ubiquitin ligases in gastrointestinal tract defines genes ontology clusters with tissue expression patterns. PMID:35413796
PTH2R is related to cell proliferation and migration in ovarian cancer: a multi-omics analysis of bioinformatics and experiments. PMID:35410353
Comparative transcriptomic analysis of two Cucumis melo var. saccharinus germplasms differing in fruit physical and chemical characteristics. PMID:35410167
Identification and New Indication of Melanin-Concentrating Hormone Receptor 1 (MCHR1) Antagonist Derived from Machine Learning and Transcriptome-Based Drug Repositioning Approaches. PMID:35409167
Environmental Phenol and Paraben Exposure Risks and Their Potential Influence on the Gene Expression Involved in the Prognosis of Prostate Cancer. PMID:35409038
Circulating Vitreous microRNA as Possible Biomarker in High Myopic Eyes with Macular Hole. PMID:35409006
Enhancement Mechanism of Stibnite Dissolution Mediated by Acidithiobacillus ferrooxidans under Extremely Acidic Condition. PMID:35408938
Machine-Learning Analysis of Serum Proteomics in Neuropathic Pain after Nerve Injury in Breast Cancer Surgery Points at Chemokine Signaling via SIRT2 Regulation. PMID:35408848
Label-Free LC-MS/MS Analysis Reveals Different Proteomic Profiles between Egg Yolks of Silky Fowl and Ordinary Chickens. PMID:35407122
Chemerin Effect on the Endometrial Proteome of the Domestic Pig during Implantation Obtained by LC-MS/MS Analysis. PMID:35406725
Osteogenic Commitment of Human Periodontal Ligament Cells Is Predetermined by Methylation, Chromatin Accessibility and Expression of Key Transcription Factors. PMID:35406691
Transcriptional CDK Inhibitors as Potential Treatment Option for Testicular Germ Cell Tumors. PMID:35406461
Integrative Analyses of Antler Cartilage Transcriptome and Proteome of Gansu Red Deer (Cervus elaphus kansuensis) at Different Growth Stages. PMID:35405922
Multifaced regulator: RNA binding proteins and their roles in hematopoiesis. PMID:35402803
Combining biomedical knowledge graphs and text to improve predictions for drug-target interactions and drug-indications. PMID:35402106
TMT labeled comparative proteomic analysis reveals spleen active immune responses during Clostridium perfringens type C infected piglet diarrhea. PMID:35402105
An engineered nano-liposome-human ACE2 decoy neutralizes SARS-CoV-2 Spike protein-induced inflammation in both murine and human macrophages. PMID:35401811
Effects of Luteinizing Hormone Releasing Hormone A2 on Gonad Development in Juvenile Amur Sturgeon, Acipenser schrenckii, Revealed by Transcriptome Profiling Analysis. PMID:35401695
A Secondary Metabolism Pathway Involved in the Production of a Putative Toxin Is Expressed at Early Stage of Monilinia laxa Infection. PMID:35401637
Integrated Metabolomic and Transcriptomic Analysis and Identification of Dammarenediol-II Synthase Involved in Saponin Biosynthesis in Gynostemma longipes. PMID:35401630
Comparative Transcriptome Profiling Analysis Reveals the Adaptive Molecular Mechanism of Yellow-Green Leaf in Rosa beggeriana 'Aurea'. PMID:35401615
Single-Cell Profiling Reveals Heterogeneity of Primary and Lymph Node Metastatic Tumors and Immune Cell Populations and Discovers Important Prognostic Significance of CCDC43 in Oral Squamous Cell Carcinoma. PMID:35401551
Preclinical Studies on Convalescent Human Immune Plasma-Derived Exosome: Omics and Antiviral Properties to SARS-CoV-2. PMID:35401544
Pangenome Analysis of the Soilborne Fungal Phytopathogen Rhizoctonia solani and Development of a Comprehensive Web Resource: RsolaniDB. PMID:35401459
Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment. PMID:35395188
FindIT2: an R/Bioconductor package to identify influential transcription factor and targets based on multi-omics data. PMID:35392802
Acetate Degradation at Low pH by the Moderately Acidophilic Sulfate Reducer Acididesulfobacillus acetoxydans gen. nov. sp. nov. PMID:35391737
Description and genome analysis of Luteimonas viscosa sp. nov., a novel bacterium isolated from soil of a sunflower field. PMID:35391590
Predicted mouse interactome and network-based interpretation of differentially expressed genes. PMID:35390003
Providing Adverse Outcome Pathways from the AOP-Wiki in a Semantic Web Format to Increase Usability and Accessibility of the Content. PMID:35388368
Hierarchical multi-label classification based on LSTM network and Bayesian decision theory for LncRNA function prediction. PMID:35388048
Engineering an enthesis-like graft for rotator cuff repair: An approach to fabricate highly biomimetic scaffold capable of zone-specifically releasing stem cell differentiation inducers. PMID:35386315
Co-Expression Network Modeling Identifies Specific Inflammation and Neurological Disease-Related Genes mRNA Modules in Mood Disorder. PMID:35386281
MDN1 Mutation Is Associated With High Tumor Mutation Burden and Unfavorable Prognosis in Breast Cancer. PMID:35386280
Nextcast: A software suite to analyse and model toxicogenomics data. PMID:35386103
Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma. PMID:35385731
Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma. PMID:35385730
Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study. PMID:35385482
A high-quality assembly reveals genomic characteristics, phylogenetic status, and causal genes for leucism plumage of Indian peafowl. PMID:35383847
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease. PMID:35383280
Genome-scale transcriptomic insights into the gene co-expression network of seed abortion in triploid Siraitia grosvenorii. PMID:35382733
Harmonizing model organism data in the Alliance of Genome Resources. PMID:35380658
MOET: a web-based gene set enrichment tool at the Rat Genome Database for multiontology and multispecies analyses. PMID:35380657
JaponicusDB: rapid deployment of a model organism database for an emerging model species. PMID:35380656
MTD: a unique pipeline for host and meta-transcriptome joint and integrative analyses of RNA-seq data. PMID:35380623
Cellular and transcriptional diversity over the course of human lactation. PMID:35377806
Proteomic Response Revealed Signaling Pathways Involving in the Mechanism of Polymyxin B-Induced Melanogenesis. PMID:35377227
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques. PMID:35377064
d-Serine Mediates Cellular Proliferation for Kidney Remodeling. PMID:35372967
Spatial proteomics reveals subcellular reorganization in human keratinocytes exposed to UVA light. PMID:35372811
Dental EHR-infused Persona Ontologies to Enrich Dental Dialogue Interaction of Agents. PMID:35371617
Transcriptome Analysis Reveals a Gene Expression Pattern That Contributes to Sugarcane Bud Propagation Induced by Indole-3-Butyric Acid. PMID:35371161
MAG2 and MAL Regulate Vesicle Trafficking and Auxin Homeostasis With Functional Redundancy. PMID:35371137
Pituitary Gonadotropin Gene Expression During Induced Onset of Postsmolt Maturation in Male Atlantic Salmon: In Vivo and Tissue Culture Studies. PMID:35370944
Comprehensive Analysis of the Transcriptome-Wide m6A Methylation in Mouse Pachytene Spermatocytes and Round Spermatids. PMID:35368708
Parthenolide leads to proteomic differences in thyroid cancer cells and promotes apoptosis. PMID:35366876
A high-quality assembled genome and its comparative analysis decode the adaptive molecular mechanism of the number one Chinese cotton variety CRI-12. PMID:35365835
Transcriptome-wide association study for postpartum depression implicates altered B-cell activation and insulin resistance. PMID:35365803
Proteome profiling reveals changes in energy metabolism, transport and antioxidation during drought stress in Nostoc flagelliforme. PMID:35365086
Non-linear archetypal analysis of single-cell RNA-seq data by deep autoencoders. PMID:35363784
Intermittent prednisone treatment in mice promotes exercise tolerance in obesity through adiponectin. PMID:35363257
Stimulation of the hepatoportal nerve plexus with focused ultrasound restores glucose homoeostasis in diabetic mice, rats and swine. PMID:35361935
NeuroSCORE is a genome-wide omics-based model that identifies candidate disease genes of the central nervous system. PMID:35361823
Gene expression study in monocytes: evidence of inflammatory dysregulation in early-onset obsessive-compulsive disorder. PMID:35361798
Genomic heterogeneity underlies multidrug resistance in Pseudomonas aeruginosa: A population-level analysis beyond susceptibility testing. PMID:35358221
Iron-Induced Respiration Promotes Antibiotic Resistance in Actinomycete Bacteria. PMID:35357210
Species Persistence with Hybridization in Toad-Headed Lizards Driven by Divergent Selection and Low Recombination. PMID:35356979
Mass Spectrometric Behavior and Molecular Mechanisms of Fermented Deoxyanthocyanidins to Alleviate Ulcerative Colitis Based on Network Pharmacology. PMID:35356765
Whole-Genome and Transcriptome Sequencing-Based Characterization of Bacillus Cereus NR1 From Subtropical Marine Mangrove and Its Potential Role in Sulfur Metabolism. PMID:35356521
Antigen-Presenting B Cells Program the Efferent Lymph T Helper Cell Response. PMID:35355990
Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids. PMID:35354790
Coronavirus Host Genetics South Africa (COHG-SA) database-a variant database for gene regions associated with SARS-CoV-2 outcomes. PMID:35351987
Networks and Graphs Discovery in Metabolomics Data Analysis and Interpretation. PMID:35350714
Network Crosstalk as a Basis for Drug Repurposing. PMID:35350247
Genomic diversity and post-admixture adaptation in the Uyghurs. PMID:35350227
Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study. PMID:35349355
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci. PMID:35347128
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. PMID:35346299
Integrative analyses of biomarkers and pathways for heart failure. PMID:35346191
Hippocampus RNA Sequencing of Pentylenetetrazole-Kindled Rats and Upon Treatment of Novel Chemical Q808. PMID:35345815
LRP1B is a Potential Biomarker for Tumor Immunogenicity and Prognosis of HCC Patients Receiving ICI Treatment. PMID:35345553
Genome Sequence and Description of Paracoccus denitrificans Strain R-1, Isolated from Activated Sludge. PMID:35343764
Screening of Potential Key Biomarkers for Ewing Sarcoma: Evidence from Gene Array Analysis. PMID:35342299
Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression. PMID:35340765
Global DNA methylation profiles of buffalo (Bubalus bubalis) preimplantation embryos produced by handmade cloning and in vitro fertilization. PMID:35338228
De novo assembly of a fruit transcriptome set identifies AmMYB10 as a key regulator of anthocyanin biosynthesis in Aronia melanocarpa. PMID:35337270
GXP: Analyze and Plot Plant Omics Data in Web Browsers. PMID:35336631
Polyopes affinis Suppressed IFN-γ- and TNF-α-Induced Inflammation in Human Keratinocytes via Down-Regulation of the NF-κB and STAT1 Pathways. PMID:35335198
Whole-genome sequencing and gene sharing network analysis powered by machine learning identifies antibiotic resistance sharing between animals, humans and environment in livestock farming. PMID:35333870
Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro. PMID:35332340
Genomic signatures of high-altitude adaptation and chromosomal polymorphism in geladas. PMID:35332281
Stripenn detects architectural stripes from chromatin conformation data using computer vision. PMID:35332165
Parallel sequence tagging for concept recognition. PMID:35331131
In silico Analysis of Publicly Available Transcriptomics Data Identifies Putative Prognostic and Therapeutic Molecular Targets for Papillary Thyroid Carcinoma. PMID:35330879
Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy. PMID:35330838
Characterization of Vegetative Incompatibility in Morchella importuna and Location of the Related-Genes by Bulk Segregant Analysis. PMID:35330770
HSPB8 is a Potential Prognostic Biomarker that Correlates With Immune Cell Infiltration in Bladder Cancer. PMID:35330734
Landscape of Molecular Crosstalk Perturbation between Lung Cancer and COVID-19. PMID:35329141
High Resistance to Quinclorac in Multiple-Resistant Echinochloa colona Associated with Elevated Stress Tolerance Gene Expression and Enriched Xenobiotic Detoxification Pathway. PMID:35328069
Functional Similarities of Protein-Coding Genes in Topologically Associating Domains and Spatially-Proximate Genomic Regions. PMID:35328034
Characterization of Mitochondrial Proteome and Function in Luminal A and Basal-like Breast Cancer Subtypes Reveals Alteration in Mitochondrial Dynamics and Bioenergetics Relevant to Their Diagnosis. PMID:35327574
Functional Enrichment Analysis of Regulatory Elements. PMID:35327392
Screening Repurposed Antiviral Small Molecules as Antimycobacterial Compounds by a Lux-Based phoP Promoter-Reporter Platform. PMID:35326832
Bioinformatics Analysis and Identification of Potential Genes Associated with Pathogenesis and Prognosis of Gastric Cancer. PMID:35325407
Whole Blood Metabolite Profiles Reflect Changes in Energy Metabolism in Heart Failure. PMID:35323659
Immune Defense Mechanism of Reticulitermes chinensis Snyder (Blattodea: Isoptera) against Serratia marcescens Bizio. PMID:35323524
Outstanding prognostic value of novel ferroptosis-related genes in chemoresistance osteosarcoma patients. PMID:35322804
Identification of the TF-miRNA-mRNA co-regulatory networks involved in sepsis. PMID:35322335
Identification and Characterization of the Roles of circCASP9 in Gastric Cancer Based on a circRNA-miRNA-mRNA Regulatory Network. PMID:35320976
High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response. PMID:35319251
Incorporating regulatory interactions into gene-set analyses for GWAS data: A controlled analysis with the MAGMA tool. PMID:35316269
Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing. PMID:35314823
Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures. PMID:35314697
Identification of differentially expressed genes and signaling pathways with Candida infection by bioinformatics analysis. PMID:35314002
Transcriptome Analysis Revealed a Cold Stress-Responsive Transcription Factor, PaDREB1A, in Plumbago auriculata That Can Confer Cold Tolerance in Transgenic Arabidopsis thaliana. PMID:35310656
Endophytic Bacterium Serratia plymuthica From Chinese Leek Suppressed Apple Ring Rot on Postharvest Apple Fruit. PMID:35310399
GOing Forward With the Cardiac Conduction System Using Gene Ontology. PMID:35309148
Comprehensive Transcriptome Analysis of Stem-Differentiating Xylem Upon Compression Stress in Cunninghamia Lanceolata. PMID:35309135
Small genetic variation affecting mRNA isoforms associated with marbling and meat color in beef cattle. PMID:35305194
Parvimonas micra is associated with tumour immune profiles in molecular subtypes of colorectal cancer. PMID:35301576
Transcriptogram analysis reveals relationship between viral titer and gene sets responses during Corona-virus infection. PMID:35300459
Identification of Down-Regulated ADH1C is Associated With Poor Prognosis in Colorectal Cancer Using Bioinformatics Analysis. PMID:35300114
Protocol for isolation and functional validation of label-retaining quiescent colorectal cancer stem cells from patient-derived organoids for RNA-seq. PMID:35300001
Chromosome-Scale Assembly of the Dendrobium nobile Genome Provides Insights Into the Molecular Mechanism of the Biosynthesis of the Medicinal Active Ingredient of Dendrobium. PMID:35299950
Impact of 6 month conjugated equine estrogen versus estradiol-treatment on biomarkers and enriched gene sets in healthy mammary tissue of non-human primates. PMID:35298474
A multidimensional coding architecture of the vagal interoceptive system. PMID:35296859
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma. PMID:35296667
Comparative Analysis of Gene Expression Profiles in the Adipose Tissue of Obese Adult Mice With Rapid Infantile Growth After Undernourishment In Utero. PMID:35295992
Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer's Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia. PMID:35295737
Missing Links Between Gene Function and Physiology in Genomics. PMID:35295568
Beyond AOPs: A Mechanistic Evaluation of NAMs in DART Testing. PMID:35295212
Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. PMID:35294868
Identification of hub genes and pathways in bladder cancer using bioinformatics analysis. PMID:35291419
Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy. PMID:35288587
EnsembleFam: towards more accurate protein family prediction in the twilight zone. PMID:35287576
Analysis of the role and mechanism of EGCG in septic cardiomyopathy based on network pharmacology. PMID:35287352
Bacterial Homologs of Progestin and AdipoQ Receptors (PAQRs) Affect Membrane Energetics Homeostasis but Not Fluidity. PMID:35285724
Chondroitin Sulfate Proteoglycans Are De Facto Cellular Receptors for Human Papillomavirus 16 under High Serum Conditions. PMID:35285688
Transcriptomic Analysis Reveal the Molecular Mechanisms of Seed Coat Development in Cucurbita pepo L. PMID:35283914
Multi-Approach Analysis Reveals Pathways of Cold Tolerance Divergence in Camellia japonica. PMID:35283896
Inhibition of miR-128 Enhances Vocal Sequence Organization in Juvenile Songbirds. PMID:35283744
The Key Genes Underlying Pathophysiology Correlation Between the Acute Myocardial Infarction and COVID-19. PMID:35282650
Cold Exposure Induces Depot-Specific Alterations in Fatty Acid Composition and Transcriptional Profile in Adipose Tissues of Pigs. PMID:35282453
Establishing a competing endogenous RNA (ceRNA)-immunoregulatory network associated with the progression of Alzheimer's disease. PMID:35282112
Network Analysis Reveals Different Cellulose Degradation Strategies Across Trichoderma harzianum Strains Associated With XYR1 and CRE1. PMID:35281818
Conserved Regulatory Pathways for Stock-Scion Healing Revealed by Comparative Analysis of Arabidopsis and Tomato Grafting Transcriptomes. PMID:35281699
Insights Into the Impact of Small RNA SprC on the Metabolism and Virulence of Staphylococcus aureus. PMID:35281456
Identification of differentially expressed and methylated genes and construction of a co-expression network in age-related macular degeneration. PMID:35280389
Circ_0001174 facilitates osteosarcoma cell proliferation, migration, and invasion by targeting the miR-186-5p/MACC1 axis. PMID:35279159
Chromosome-level genome assembly, annotation, and phylogenomics of the gooseneck barnacle Pollicipes pollicipes. PMID:35277961
Genome-wide transcript and protein analysis highlights the role of protein homeostasis in the aging mouse heart. PMID:35277432
Transcriptome characterization of Larrea tridentata and identification of genes associated with phenylpropanoid metabolic pathways. PMID:35275977
GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate. PMID:35275720
Proteome Analysis of Urinary Biomarkers in a Bovine IRBP-Induced Uveitis Rat Model via Data-Independent Acquisition and Parallel Reaction Monitoring Proteomics. PMID:35274006
Pan-Cancer Analysis and Validation Reveals that D-Dimer-Related Genes are Prognostic and Downregulate CD8+ T Cells via TGF-Beta Signaling in Gastric Cancer. PMID:35274004
Integrative Analyses of Genes Associated With Otologic Disorders in Turner Syndrome. PMID:35273637
Centrosomal protein 290 is a novel prognostic indicator that modulates liver cancer cell ferroptosis via the Nrf2 pathway. PMID:35271462
Protoplast Dissociation and Transcriptome Analysis Provides Insights to Salt Stress Response in Cotton. PMID:35269989
Combined Transcriptomic and Proteomic Profiling of E. coli under Microaerobic versus Aerobic Conditions: The Multifaceted Roles of Noncoding Small RNAs and Oxygen-Dependent Sensing in Global Gene Expression Control. PMID:35269716
Comprehensive Analysis of the Effect of 20(R)-Ginsenoside Rg3 on Stroke Recovery in Rats via the Integrative miRNA-mRNA Regulatory Network. PMID:35268674
Learning Ability and Hippocampal Transcriptome Responses to Early and Later Life Environmental Complexities in Dual-Purpose Chicks. PMID:35268235
WhiB4 Is Required for the Reactivation of Persistent Infection of Mycobacterium marinum in Zebrafish. PMID:35266819
FlyBase: a guided tour of highlighted features. PMID:35266522
Yin Yang 1 regulates ITGAV and ITGB1, contributing to improved prognosis of colorectal cancer. PMID:35266011
A non-canonical tricarboxylic acid cycle underlies cellular identity. PMID:35264789
Uncovering the genetic profiles underlying the intrinsic organization of the human cerebellum. PMID:35264730
CRISPR/Cas9-Mediated Insertion of HIV Long Terminal Repeat within BACH2 Promotes Expansion of T Regulatory-like Cells. PMID:35264460
Comparative whole transcriptome analysis of Parkinson's disease focusing on the efficacy of zonisamide. PMID:35264450
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts. PMID:35263568
Whole genome sequence of pan drug-resistant clinical isolate of Acinetobacter baumannii ST1890. PMID:35263355
Urgent need for consistent standards in functional enrichment analysis. PMID:35263338
RNA-seq and integrated network analysis reveals the hub genes and key pathway of paclitaxel inhibition on Adriamycin resistant diffuse large B cell lymphoma cells. PMID:35263200
ImmuneData: an integrated data discovery system for immunology data repositories. PMID:35262674
Tsp-1 is involved in DNA stability through Tgf-β1 activation domain in cone photoreceptor 661 W cells. PMID:35260935
Computing microRNA-gene interaction networks in pan-cancer using miRDriver. PMID:35260634
Comparative analysis of the Mercenaria mercenaria genome provides insights into the diversity of transposable elements and immune molecules in bivalve mollusks. PMID:35260071
Identification of Potential Key Biomarkers and Immune Infiltration in Oral Lichen Planus. PMID:35256894
RNA-Seq reveals miRNA role in thermogenic regulation in brown adipose tissues of goats. PMID:35255830
A multi-network integration approach for measuring disease similarity based on ncRNA regulation and heterogeneous information. PMID:35255810
Whole-genome sequencing reveals host factors underlying critical COVID-19. PMID:35255492
Transcriptome Analysis of Plasmodium falciparum Isolates From Benin Reveals Specific Gene Expression Associated With Cerebral Malaria. PMID:35255125
Draft genome sequence of myo-inositol utilizing Aeromonas dhakensis 1P11S3 isolated from striped catfish (Pangasianodon hypopthalmus) in a local fish farm in Malaysia. PMID:35252492
Identification and Comprehensive Analysis of FREM2 Mutation as a Potential Prognostic Biomarker in Colorectal Cancer. PMID:35252356
Impact of Pals1 on Expression and Localization of Transporters Belonging to the Solute Carrier Family. PMID:35252349
Indolethylamine-N-Methyltransferase Inhibits Proliferation and Promotes Apoptosis of Human Prostate Cancer Cells: A Mechanistic Exploration. PMID:35252179
A High-Quality, Chromosome-Level Genome Provides Insights Into Determinate Flowering Time and Color of Cotton Rose (Hibiscus mutabilis). PMID:35251086
Genome and Comparative Transcriptome Dissection Provide Insights Into Molecular Mechanisms of Sclerotium Formation in Culinary-Medicinal Mushroom Pleurotus tuber-regium. PMID:35250915
Smoking Status and Type 2 Diabetes, and Cardiovascular Disease: A Comprehensive Analysis of Shared Genetic Etiology and Causal Relationship. PMID:35250867
iTRAQ Proteomic Analysis of Interactions Between 20E and Phospholipase C in Apolygus lucorum (Meyer-Dür). PMID:35250643
PM2.5 exposure during pregnancy is associated with altered placental expression of lipid metabolic genes in a US birth cohort. PMID:35248564
Plasma proteome changes linked to late phase response after inhaled allergen challenge in asthmatics. PMID:35248034
DrGA: cancer driver gene analysis in a simpler manner. PMID:35247965
Biomimetic radiosensitizers unlock radiogenetics for local interstitial radiotherapy to activate systematic immune responses and resist tumor metastasis. PMID:35246159
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease. PMID:35245467
Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes. PMID:35245348
Immunomodulatory potential of in vivo natural killer T (NKT) activation by NKTT320 in Mauritian-origin cynomolgus macaques. PMID:35243248
Dynamic Control Balancing Cell Proliferation and Inflammation is Crucial for an Effective Immune Response to Malaria. PMID:35242812
Identification of Important Genes Involved in the Sex-Differentiation Mechanism of Oriental River Prawn, Macrobrachium nipponense, During the Gonad Differentiation and Development Period. PMID:35242165
Altered Expression of Specific MicroRNAs in Plasma of Aneurysmal Subarachnoid Hemorrhage Patients. PMID:35242102
Promoter/enhancer-based controllability of regulatory networks. PMID:35241702
Tig1 regulates proximo-distal identity during salamander limb regeneration. PMID:35241664
Upregulated YB-1 protein promotes glioblastoma growth through a YB-1/CCT4/mLST8/mTOR pathway. PMID:35239512
Benchmarking the proteomic profile of animal models of mesial temporal epilepsy. PMID:35238489
Methylation- and homologous recombination deficiency-related mutant genes predict the prognosis of lung adenocarcinoma. PMID:35238419
Modeling multi-scale data via a network of networks. PMID:35238343
Investigation of miR-21-5p Key Target Genes and Pathways in Head and Neck Squamous Cell Carcinoma Based on TCGA Database and Bioinformatics Analysis. PMID:35235474
Novel genetic basis of resistance to Bt toxin Cry1Ac in Helicoverpa zea. PMID:35234875
Detection of Prognostic Biomarkers for Hepatocellular Carcinoma through CircRNA-associated CeRNA Analysis. PMID:35233376
Landscape genomics of the streamside salamander: Implications for species management in the face of environmental change. PMID:35233244
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia. PMID:35232995
Connectomic-genetic signatures in the cerebral small vessel disease. PMID:35231560
Molecular phylogeography and species distribution modelling evidence of 'oceanic' adaptation for Actinidia eriantha with a refugium along the oceanic-continental gradient in a biodiversity hotspot. PMID:35227218
Comparative transcriptomes of three different skin sites for the Asiatic toad (Bufo gargarizans). PMID:35223212
SMRT sequencing of full-length transcriptome and gene expression analysis in two chemical types of Pogostemon cablin (Blanco) Benth. PMID:35223208
Polymerase II-Associated Factor 1 Complex-Regulated FLOWERING LOCUS C-Clade Genes Repress Flowering in Response to Chilling. PMID:35222476
Investigating the Mechanism of Unilateral Cross Incompatibility in Longan (Dimocarpus longan Lour.) Cultivars (Yiduo × Shixia). PMID:35222456
Single-Cell RNA Sequencing Identifies Intra-Graft Population Heterogeneity in Acute Heart Allograft Rejection in Mouse. PMID:35222420
Multi-Omics Profiling Specifies Involvement of Alternative Ribosomal Proteins in Response to Zinc Limitation in Mycobacterium smegmatis. PMID:35222334
Dynamic Gene Expression and Alternative Splicing Events Demonstrate Co-Regulation of Testicular Differentiation and Maturation by the Brain and Gonad in Common Carp. PMID:35222265
Single-Cell RNA Sequencing Characterizes the Molecular Heterogeneity of the Larval Zebrafish Optic Tectum. PMID:35221915
MYH10 Governs Adipocyte Function and Adipogenesis through Its Interaction with GLUT4. PMID:35216482
Transient Agarose Spot (TAS) Assay: A New Method to Investigate Cell Migration. PMID:35216230
Deciphering the Interactions of SARS-CoV-2 Proteins with Human Ion Channels Using Machine-Learning-Based Methods. PMID:35215201
Analysis of Liver Responses to Non-alcoholic Steatohepatitis by mRNA-Sequencing. PMID:35212994
Student biocuration projects as a learning environment. PMID:35211294
PREGO: A Literature and Data-Mining Resource to Associate Microorganisms, Biological Processes, and Environment Types. PMID:35208748
Application of Whole Exome Sequencing and Functional Annotations to Identify Genetic Variants Associated with Marfan Syndrome. PMID:35207686
Understanding of Waggle Dance in the Honey Bee (Apis mellifera) from the Perspective of Long Non-Coding RNA. PMID:35206685
Haplotype-Resolved Genome Analyses Reveal Genetically Distinct Nuclei within a Commercial Cultivar of Lentinula edodes. PMID:35205921
Genome-Wide Association Study Reveals Genetic Architecture and Candidate Genes for Yield and Related Traits under Terminal Drought, Combined Heat and Drought in Tropical Maize Germplasm. PMID:35205393
Genomic Analyses of the Fungus Paraconiothyrium sp. Isolated from the Chinese White Wax Scale Insect Reveals Its Symbiotic Character. PMID:35205383
Characterization of the Genomic Landscape in Cervical Cancer by Next Generation Sequencing. PMID:35205332
miRNA and lncRNA Expression Networks Modulate Cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells. PMID:35205253
Unlocking the Memory Component of Alzheimer's Disease: Biological Processes and Pathways across Brain Regions. PMID:35204764
Single-Cell Sequencing Reveals an Intrinsic Heterogeneity of the Preovulatory Follicular Microenvironment. PMID:35204732
Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress. PMID:35204678
Phosphoproteomic Analysis of Breast Cancer-Derived Small Extracellular Vesicles Reveals Disease-Specific Phosphorylated Enzymes. PMID:35203617
Genes Involved in Immune Reinduction May Constitute Biomarkers of Response for Metastatic Melanoma Patients Treated with Targeted Therapy. PMID:35203494
Chemerin Impact on Alternative mRNA Transcription in the Porcine Luteal Cells. PMID:35203364
Stage-differentiated ensemble modeling of DNA methylation landscapes uncovers salient biomarkers and prognostic signatures in colorectal cancer progression. PMID:35202405
Molecular Details of Actinomycin D-Treated MRSA Revealed via High-Dimensional Data. PMID:35200643
Effect of Different Initial Fermentation pH on Exopolysaccharides Produced by Pseudoalteromonas agarivorans Hao 2018 and Identification of Key Genes Involved in Exopolysaccharide Synthesis via Transcriptome Analysis. PMID:35200619
Identification of Potential Immune Checkpoint Inhibitor Targets in Gliomas via Bioinformatic Analyses. PMID:35198632
Comparative transcriptome analysis provides insights into grain filling commonalities and differences between foxtail millet [Setaria italica (L.) P. Beauv.] varieties with different panicle types. PMID:35198264
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection. PMID:35197461
Combined use of Oxford Nanopore and Illumina sequencing yields insights into soybean structural variation biology. PMID:35197050
Functional buffering via cell-specific gene expression promotes tissue homeostasis and cancer robustness. PMID:35194081
Cultivating Lentinula edodes on Substrate Containing Composted Sawdust Affects the Expression of Carbohydrate and Aromatic Amino Acid Metabolism-Related Genes. PMID:35191774
Clusterin as a serum biomarker candidate contributes to the lung fibroblasts activation in chronic obstructive pulmonary disease. PMID:35191419
Comparative proteome analysis reveals the role of negative floral regulators and defense-related genes in phytoplasma infected sesame. PMID:35190871
Physiological and transcriptome analysis reveals the differences in nitrate content between lamina and midrib of flue-cured tobacco. PMID:35190651
Modeling oxidative injury response in human kidney organoids. PMID:35189973
Proteome-defined changes in cellular pathways for decidua and trophoblast tissues associated with location and viability of early-stage pregnancy. PMID:35189928
Genomic characterization of the world's longest selection experiment in mouse reveals the complexity of polygenic traits. PMID:35189878
Genome assembly of the JD17 soybean provides a new reference genome for comparative genomics. PMID:35188189
Graph-guided Bayesian SVM with Adaptive Structured Shrinkage Prior for High-dimensional Data. PMID:35187547
Genome Sequences of Two Strains of Prototheca wickerhamii Provide Insight Into the Protothecosis Evolution. PMID:35186789
Wei2GO: weighted sequence similarity-based protein function prediction. PMID:35186498
Proteomic Analysis of the Antibacterial Effect of Improved Dian Dao San against Propionibacterium acnes. PMID:35186097
Genome-Wide Identification of Direct Targets of ZjVND7 Reveals the Putative Roles of Whole-Genome Duplication in Sour Jujube in Regulating Xylem Vessel Differentiation and Drought Tolerance. PMID:35185994
Integration of Small RNA and Transcriptome Sequencing Reveal the Roles of miR395 and ATP Sulfurylase in Developing Seeds of Chinese Kale. PMID:35185948
Analysis of Biosynthetic Gene Clusters, Secretory, and Antimicrobial Peptides Reveals Environmental Suitability of Exiguobacterium profundum PHM11. PMID:35185816
Efficient link prediction in the protein-protein interaction network using topological information in a generative adversarial network machine learning model. PMID:35183129
DVPred: a disease-specific prediction tool for variant pathogenicity classification for hearing loss. PMID:35182233
Quantitative multiplexed proteomics analysis reveals reshaping of the lysine 2-hydroxyisobutyrylome in Fusarium graminearum by tebuconazole. PMID:35180840
Evaluating the detection ability of a range of epistasis detection methods on simulated data for pure and impure epistatic models. PMID:35180244
Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α. PMID:35179955
Hypertrophic chondrocytes serve as a reservoir for marrow-associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development. PMID:35179487
Chromosome-scale assembly and population diversity analyses provide insights into the evolution of Sapindus mukorossi. PMID:35178562
Comparative transcriptome and weighted correlation network analyses reveal candidate genes involved in chlorogenic acid biosynthesis in sweet potato. PMID:35177832
Differential Transcriptome Analysis Reveals Genes Related to Low- and High-Temperature Stress in the Fall Armyworm, Spodoptera frugiperda. PMID:35173626
Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus. PMID:35172715
Mechanism of action of Tripterygium wilfordii for treatment of idiopathic membranous nephropathy based on network pharmacology. PMID:35172688
Zika virus disrupts gene expression in human myoblasts and myotubes: Relationship with susceptibility to infection. PMID:35171909
The m6A(m)-independent role of FTO in regulating WNT signaling pathways. PMID:35169043
Haloterrigena gelatinilytica sp. nov., a new extremely halophilic archaeon isolated from salt-lake. PMID:35166931
Zebrafish information network, the knowledgebase for Danio rerio research. PMID:35166825
Factors That Affect the Rates of Adaptive and Nonadaptive Evolution at the Gene Level in Humans and Chimpanzees. PMID:35166775
Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy. PMID:35164755
MonaGO: a novel gene ontology enrichment analysis visualisation system. PMID:35164667
Comprehensive Detoxification Mechanism Assessment of Red Imported Fire Ant (Solenopsis invicta) against Indoxacarb. PMID:35164134
A Photosensitized Singlet Oxygen (1O2) Toolbox for Bio-Organic Applications: Tailoring 1O2 Generation for DNA and Protein Labelling, Targeting and Biosensing. PMID:35164045
Insights into the Steps of Breast Cancer-Brain Metastases Development: Tumor Cell Interactions with the Blood-Brain Barrier. PMID:35163822
Cold Exposure Drives Weight Gain and Adiposity following Chronic Suppression of Brown Adipose Tissue. PMID:35163791
Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells. PMID:35163371
Interactome of Arabidopsis Thaliana. PMID:35161331
Analysis of Global Gene Expression in Maize (Zea mays) Vegetative and Reproductive Tissues That Differ in Accumulation of Starch and Sucrose. PMID:35161219
Single-cell dissection of the human brain vasculature. PMID:35158371
Analysis of miRNAs Involved in Mouse Heart Injury Upon Coxsackievirus A2 Infection. PMID:35155276
Low-Level Laser Therapy Effects on Rat Blood Hemostasis Via Significant Alteration in Fibrinogen and Plasminogen Expression Level. PMID:35155144
Investigating changes of proteome in the bovine milk serum after retort processing using proteomics techniques. PMID:35154669
An Augmented High-Dimensional Graphical Lasso Method to Incorporate Prior Biological Knowledge for Global Network Learning. PMID:35154240
The Landscape of Aminoacyl-tRNA Synthetases Involved in Severe Acute Respiratory Syndrome Coronavirus 2 Infection. PMID:35153822
Gene-Interaction-Sensitive enrichment analysis in congenital heart disease. PMID:35151364
Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism. PMID:35150276
Adipose-derived stem cell spheroids are superior to single-cell suspensions to improve fat autograft long-term survival. PMID:35150064
BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding. PMID:35147915
Data Integration Challenges for Machine Learning in Precision Medicine. PMID:35145977
Classification and Association Analysis of Gerbera (Gerbera hybrida) Flower Color Traits. PMID:35145530
Identification of recurrent genetic patterns from targeted sequencing panels with advanced data science: a case-study on sporadic and genetic neurodegenerative diseases. PMID:35144616
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes. PMID:35144563
Zebrafish models of alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye. PMID:35142342
Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties. PMID:35141503
Genome Sequencing of Hericium coralloides by a Combination of PacBio RS II and Next-Generation Sequencing Platforms. PMID:35141329
Construction and Analysis of the lncRNA-miRNA-mRNA Network Based on Competing Endogenous RNA in Atrial Fibrillation. PMID:35141302
Metabolic labeling of secreted matrix to investigate cell-material interactions in tissue engineering and mechanobiology. PMID:35140408
Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells. PMID:35139387
Network inference with Granger causality ensembles on single-cell transcriptomics. PMID:35139376
Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells. PMID:35137207
Sperm acquire epididymis-derived proteins through epididymosomes. PMID:35137089
The genome of the Paleogene relic tree Bretschneidera sinensis: insights into trade-offs in gene family evolution, demographic history, and adaptive SNPs. PMID:35137004
Protein phase separation hotspots at the presynapse. PMID:35135293
Deciphering the etiology and role in oncogenic transformation of the CpG island methylator phenotype: a pan-cancer analysis. PMID:35134107
PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation. PMID:35132438
A High-Density Genetic Map Enables Genome Synteny and QTL Mapping of Vegetative Growth and Leaf Traits in Gardenia. PMID:35132310
Comparative population genomics in Tabebuia alliance shows evidence of adaptation in Neotropical tree species. PMID:35132209
Common DNA methylation changes in biliary tract cancers identify subtypes with different immune characteristics and clinical outcomes. PMID:35130881
Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish. PMID:35129436
Leaf color formation mechanisms in Alternanthera bettzickiana elucidated by metabolite and transcriptome analyses. PMID:35128619
β-catenin perturbations control differentiation programs in mouse embryonic stem cells. PMID:35128356
Identification of Key Genes and Pathways Involved in Circulating Tumor Cells in Colorectal Cancer. PMID:35127345
Shared Genetic Architecture and Causal Relationship Between Asthma and Cardiovascular Diseases: A Large-Scale Cross-Trait Analysis. PMID:35126453
GRAND: An Integrated Genome, Transcriptome Resources, and Gene Network Database for Gossypium. PMID:35126443
Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis. PMID:35126357
Exploring the total flavones of Abelmoschus manihot against IAV-induced lung inflammation by network pharmacology. PMID:35123452
RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4+ T-cell-dependent antitumor immunity. PMID:35121884
Systems-based approaches to study immunometabolism. PMID:35121805
Genomic basis for skin phenotype and cold adaptation in the extinct Steller's sea cow. PMID:35119923
Dynamic effects of chronic unpredictable mild stress on the hippocampal transcriptome in rats. PMID:35119083
PANDA2: protein function prediction using graph neural networks. PMID:35118378
Field cancerization profile-based prognosis signatures lead to more robust risk evaluation in hepatocellular carcinoma. PMID:35118360
Identification of key biomarkers and potential signaling pathway associated with poor progression of gastric cancer. PMID:35117911
Identification of biomarkers in colon cancer based on bioinformatic analysis. PMID:35117850
Key genes involved in cell cycle arrest and DNA damage repair identified in anaplastic thyroid carcinoma using integrated bioinformatics analysis. PMID:35117787
Candidate genes for predicting the survival of patients with gastric cancer: a study based on The Cancer Genome Atlas (TCGA) database. PMID:35117619
Identification of adriamycin resistance genes in breast cancer based on microarray data analysis. PMID:35117349
Discovered differentially expressed lncRNA AC010973.2 can act as a diagnostic and prognostic biomarker for colon adenocarcinoma. PMID:35117237
Blockade of AXL activation overcomes acquired resistance to EGFR tyrosine kinase inhibition in non-small cell lung cancer. PMID:35116995
Construction of a prognostic risk model of colorectal adenocarcinoma through integrated analysis of RNA-binding proteins. PMID:35116519
Integrated bioinformatics analysis to identify key genes related to the prognosis of esophageal squamous cell carcinoma. PMID:35116493
KRAS, YWHAE, SP1 and MSRA as biomarkers in endometrial cancer. PMID:35116456
Identification of key genes involved in tamoxifen-resistant breast cancer using bioinformatics analysis. PMID:35116374
Transcriptome analysis of the effect of a novel human serine protease inhibitor SPINK13 on gene expression in MHCC97-H cells. PMID:35116303
Identification of Inflammation-Related Biomarker Pro-ADM for Male Patients With Gout by Comprehensive Analysis. PMID:35116032
Kinsenoside Alleviates Alcoholic Liver Injury by Reducing Oxidative Stress, Inhibiting Endoplasmic Reticulum Stress, and Regulating AMPK-Dependent Autophagy. PMID:35115920
First genome-wide association study investigating blood pressure and renal traits in domestic cats. PMID:35115544
Computational image features of immune architecture is associated with clinical benefit and survival in gynecological cancers across treatment modalities. PMID:35115363
Systems pharmacology-based drug discovery and active mechanism of natural products for coronavirus pneumonia (COVID-19): An example using flavonoids. PMID:35114443
Maladaptive functional changes in alveolar fibroblasts due to perinatal hyperoxia impair epithelial differentiation. PMID:35113810
Probabilistic Graphical Models Applied to Biological Networks. PMID:35113399
Modern Approaches for Transcriptome Analyses in Plants. PMID:35113394
Deep learning program to predict protein functions based on sequence information. PMID:35111575
Use of Transposon Directed Insertion-Site Sequencing to Probe the Antibacterial Mechanism of a Model Honey on E. coli K-12. PMID:35111142
Screening of Important Markers in Peripheral Blood Mononuclear Cells to Predict Female Osteoporosis Risk Using LASSO Regression Algorithm and SVM Method. PMID:35110962
Neuropeptidergic regulation of compulsive ethanol seeking in C. elegans. PMID:35110557
Precise gene models using long-read sequencing reveal a unique poly(A) signal in Giardia lamblia. PMID:35110372
DDX10 promotes the proliferation and metastasis of colorectal cancer cells via splicing RPL35. PMID:35109823
Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation. PMID:35106469
Two heads are better than one: current landscape of integrating QSP and machine learning : An ISoP QSP SIG white paper by the working group on the integration of quantitative systems pharmacology and machine learning. PMID:35103884
Chronic Marijuana Use Is Associated with Gene Expression Changes in BAL. PMID:35103554
An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection. PMID:35102208
Universal prediction of cell-cycle position using transfer learning. PMID:35101061
De novo and comparative transcriptomic analysis explain morphological differences in Panax notoginseng taproots. PMID:35100996
Expression profiles and functions of ferroptosis-related genes in the placental tissue samples of early- and late-onset preeclampsia patients. PMID:35100981
Fission stories: using PomBase to understand Schizosaccharomyces pombe biology. PMID:35100366
Effects of abolishing Whi2 on the proteome and nitrogen catabolite repression-sensitive protein production. PMID:35100365
Endothelial Cell RNA-Seq Data: Differential Expression and Functional Enrichment Analyses to Study Phenotypic Switching. PMID:35099752
Subcellular proteomics of dopamine neurons in the mouse brain. PMID:35098924
Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity. PMID:35098922
Exploration of the Role of Serine Proteinase Inhibitor A3 in Alcohol Dependence Using Gene Expression Omnibus Database. PMID:35095596
Draft Genome Sequence of Oceanobacillus jordanicus Strain GSFE11, a Halotolerant Plant Growth-Promoting Bacterial Endophyte Isolated From the Jordan Valley. PMID:35095268
DisEnrich: Database of Enriched Regions in Human Dark Proteome. PMID:35094056
Mapping the invisible chromatin transactions of prophase chromosome remodeling. PMID:35090599
Making sense of the linear genome, gene function and TADs. PMID:35090532
Risk stratification of gastrointestinal stromal tumors by Nanostring gene expression profiling. PMID:35089395
Increased trunk fat is associated with altered gene expression in breast tissue of normal weight women. PMID:35087024
Simple But Efficacious Enrichment of Integral Membrane Proteins and Their Interactions for In-Depth Membrane Proteomics. PMID:35085786
From communities to protein complexes: A local community detection algorithm on PPI networks. PMID:35085263
Dynamic Functional Connectivity Alterations and Their Associated Gene Expression Pattern in Autism Spectrum Disorders. PMID:35082596
Gene and metabolite expression dependence on body mass index in human myocardium. PMID:35082386
Differential roles for DNAJ isoforms in HTT-polyQ and FUS aggregation modulation revealed by chaperone screens. PMID:35082301
Proteomic screen reveals diverse protein transport between connected neurons in the visual system. PMID:35081342
Hierarchical regulation of autophagy during adipocyte differentiation. PMID:35081114
Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq-guided combination with sapanisertib. PMID:35080986
Comparison of Epidermal Gene Expression Profiles in Mice Aged 1 to 20 Months. PMID:35079219
Haploidy in somatic cells is induced by mature oocytes in mice. PMID:35079104
Characterization of the COPD alveolar niche using single-cell RNA sequencing. PMID:35078977
The role of SPI1-TYROBP-FCER1G network in oncogenesis and prognosis of osteosarcoma, and its association with immune infiltration. PMID:35078433
Graphlet eigencentralities capture novel central roles of genes in pathways. PMID:35077468
A simple guide to de novo transcriptome assembly and annotation. PMID:35076693
Proteome alterations in the aqueous humor reflect structural and functional phenotypes in patients with advanced normal-tension glaucoma. PMID:35075201
Interventional- and amputation-stage muscle proteomes in the chronically threatened ischemic limb. PMID:35073463
Evaluation of deep convolutional neural networks for in situ hybridization gene expression image representation. PMID:35073334
A simplified protocol for performing MAGMA/H-MAGMA gene set analysis utilizing high-performance computing environments. PMID:35072112
Identification of Molecular Biomarkers and Key Pathways for Esophageal Carcinoma (EsC): A Bioinformatics Approach. PMID:35071597
A comprehensive characterization of the transcriptome in enzalutamide resistance prostate cancer. PMID:35071476
Identification of key genes associated with esophageal adenocarcinoma based on bioinformatics analysis. PMID:35071405
Prediction of the Mechanisms by Which Quercetin Enhances Cisplatin Action in Cervical Cancer: A Network Pharmacology Study and Experimental Validation. PMID:35070983
Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts. PMID:35070171
Potential biomarkers of acute myocardial infarction based on co-expression network analysis. PMID:35069843
Integrative Analysis of the Metabolome and Transcriptome of a Cultivated Pepper and Its Wild Progenitor Chiltepin (Capsicum annuum L. var. glabriusculum) Revealed the Loss of Pungency During Capsicum Domestication. PMID:35069640
Aggregatimonas sangjinii gen. nov., sp. nov., a novel silver nanoparticle synthesizing bacterium belonging to the family Flavobacteriaceae. PMID:35066733
RNA-seq-based transcriptomic analysis of AHL-induced biofilm and pyocyanin inhibition in Pseudomonas aeruginosa by Lactobacillus brevis. PMID:35066679
A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. PMID:35065713
Tissue-specific multi-omics analysis of atrial fibrillation. PMID:35064145
HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk. PMID:35062349
Molecular mechanism of inhibitory effects of melatonin on prostate cancer cell proliferation, migration and invasion. PMID:35061708
Transcriptomic profiling suggests candidate molecular responses to waterlogging in cassava. PMID:35061680
Differences in peripheral immune system gene expression in frontotemporal degeneration. PMID:35060553
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease. PMID:35059728
Scenes From Tick Physiology: Proteins of Sialome Talk About Their Biological Processes. PMID:35059322
A Pilot Study of Gene Expression Analysis in Peripheral Blood Mononuclear Cells in Response to a Hypocaloric Mediterranean Diet. PMID:35059043
Early-life viral infections are associated with disadvantageous immune and microbiota profiles and recurrent respiratory infections. PMID:35058634
Quantitative Proteome and Transcriptome Dynamics Analysis Reveals Iron Deficiency Response Networks and Signature in Neuronal Cells. PMID:35056799
Transcriptome Analysis of Arbuscular Mycorrhizal Casuarina glauca in Damage Mitigation of Roots on NaCl Stress. PMID:35056464
Bacillus amyloliquefaciens SN16-1-Induced Resistance System of the Tomato against Rhizoctonia solani. PMID:35055983
The Fungus Metarhizium sp. BCC 4849 Is an Effective and Safe Mycoinsecticide for the Management of Spider Mites and Other Insect Pests. PMID:35055885
Biallelic Variants in PYROXD2 Cause a Severe Infantile Metabolic Disorder Affecting Mitochondrial Function. PMID:35055180
Towards an Ideal In Cell Hybridization-Based Strategy to Discover Protein Interactomes of Selected RNA Molecules. PMID:35055128
Identification of Core Genes and Pathways in Melanoma Metastasis via Bioinformatics Analysis. PMID:35054979
Thirteen Independent Genetic Loci Associated with Preserved Processing Speed in a Study of Cognitive Resilience in 330,097 Individuals in the UK Biobank. PMID:35052462
Identification of Phosphorus Stress Related Proteins in the Seedlings of Dongxiang Wild Rice (Oryza Rufipogon Griff.) Using Label-Free Quantitative Proteomic Analysis. PMID:35052448
Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling. PMID:35052435
Capturing SNP Association across the NK Receptor and HLA Gene Regions in Multiple Sclerosis by Targeted Penalised Regression Models. PMID:35052430
Effects of the Expression of Random Sequence Clones on Growth and Transcriptome Regulation in Escherichia coli. PMID:35052392
Meta-Analysis of Transcriptome-Wide Association Studies across 13 Brain Tissues Identified Novel Clusters of Genes Associated with Nicotine Addiction. PMID:35052378
An Integrative Sialomic Analysis Reveals Molecules From Triatoma sordida (Hemiptera: Reduviidae). PMID:35047420
Targeted gene silencing in the nervous system with CRISPR-Cas13. PMID:35044815
Chromosomal-level genome and multi-omics dataset of Pueraria lobata var. thomsonii provide new insights into legume family and the isoflavone and puerarin biosynthesis pathways. PMID:35043180
Interaction of Periplasmic Fab Production and Intracellular Redox Balance in Escherichia coli Affects Product Yield. PMID:35041397
Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium. PMID:35037831
Identification of potential immunotherapy biomarkers for breast cancer by bioinformatics analysis. PMID:35037689
Identification of prognostic biomarkers in papillary renal cell carcinoma and PTTG1 may serve as a biomarker for predicting immunotherapy response. PMID:35037540
The initial expression alterations occurring to transcription factors during the formation of breast cancer: Evidence from bioinformatics. PMID:35037412
Key genes associated with prognosis and metastasis of clear cell renal cell carcinoma. PMID:35036081
Screening and Identification of Key Biomarkers in Lower Grade Glioma via Bioinformatical Analysis. PMID:35035531
Quantitative Metaproteomics and Activity-based Protein Profiling of Patient Fecal Microbiome Identifies Host and Microbial Serine-type Endopeptidase Activity Associated With Ulcerative Colitis. PMID:35033677
Core promoter mutation contributes to abnormal gene expression in bladder cancer. PMID:35033028
Transcriptome analysis of Auricularia fibrillifera fruit-body responses to drought stress and rehydration. PMID:35033026
Assigning protein function from domain-function associations using DomFun. PMID:35033002
Pathogen resistance in Sphagneticola trilobata (Singapore daisy): molecular associations and differentially expressed genes in response to disease from a widespread fungus. PMID:35031940
Comparative transcriptome analysis of the cold resistance of the sterile rice line 33S. PMID:35030196
BATF promotes group 2 innate lymphoid cell-mediated lung tissue protection during acute respiratory virus infection. PMID:35030033
Schisandrin B suppresses osteosarcoma lung metastasis in vivo by inhibiting the activation of the Wnt/β‑catenin and PI3K/Akt signaling pathways. PMID:35029287
Promising novel biomarkers and candidate small-molecule drugs for lung adenocarcinoma: Evidence from bioinformatics analysis of high-throughput data. PMID:35028418
Identification of Differentially Expressed Genes and Pathways in Human Atrial Fibrillation by Bioinformatics Analysis. PMID:35023949
GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia. PMID:35023831
The amniotic fluid proteome changes with gestational age in normal pregnancy: a cross-sectional study. PMID:35022423
Subcellular and regional localization of mRNA translation in midbrain dopamine neurons. PMID:35021090
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches. PMID:35021063
Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria. PMID:35020601
Recombinant HNP-1 Produced by Escherichia coli Triggers Bacterial Apoptosis and Exhibits Antibacterial Activity against Drug-Resistant Bacteria. PMID:35019682
Chromosome-level genome assembly of Bactrocera dorsalis reveals its adaptation and invasion mechanisms. PMID:35017661
Identification of the pivotal role of SPP1 in kidney stone disease based on multiple bioinformatics analysis. PMID:35016690
The impact of methodology on the reproducibility and rigor of DNA methylation data. PMID:35013473
RNAseq reveals extensive metabolic disruptions in the sensitive SF-295 cell line treated with schweinfurthins. PMID:35013404
Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets. PMID:35013229
Titanium with nanotopography attenuates the osteoclast-induced disruption of osteoblast differentiation by regulating histone methylation. PMID:35012895
Transcriptomic analysis of Pseudomonas ogarae F113 reveals the antagonistic roles of AmrZ and FleQ during rhizosphere adaption. PMID:35012704
The genome of oil-Camellia and population genomics analysis provide insights into seed oil domestication. PMID:35012630
Systematic identification of ACE2 expression modulators reveals cardiomyopathy as a risk factor for mortality in COVID-19 patients. PMID:35012625
Comprehensive analysis of expression profile and prognostic significance of interferon regulatory factors in pancreatic cancer. PMID:35012444
Potential biomarkers and signaling pathways associated with the pathogenesis of primary salivary gland carcinoma: a bioinformatics study. PMID:35012286
Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation. PMID:35011720
TMT Quantitative Proteomics Analysis Reveals the Effects of Transport Stress on Iron Metabolism in the Liver of Chicken. PMID:35011158
Systems Biology-Derived Genetic Signatures of Mastitis in Dairy Cattle: A New Avenue for Drug Repurposing. PMID:35011134
Inhibitory Effect and Potential Mechanism of Lactobacillus plantarum YE4 against Dipeptidyl Peptidase-4. PMID:35010205
Genome-Wide Variation Analysis of Four Vegetable Soybean Cultivars Based on Re-Sequencing. PMID:35009032
IL-17 Pathway Members as Potential Biomarkers of Effective Systemic Treatment and Cardiovascular Disease in Patients with Moderate-to-Severe Psoriasis. PMID:35008981
Catalase (CAT) Gene Family in Wheat (Triticum aestivum L.): Evolution, Expression Pattern and Function Analysis. PMID:35008967
The Stroma Liquid Biopsy Panel Contains a Stromal-Epithelial Gene Signature Ratio That Is Associated with the Histologic Tumor-Stroma Ratio and Predicts Survival in Colon Cancer. PMID:35008327
Chromatin profiling reveals heterogeneity in clinical isolates of the human pathogen Aspergillus fumigatus. PMID:35007279
LPCAT1 functions as a novel prognostic molecular marker in hepatocellular carcinoma. PMID:35005115
Transcriptomic Responses of Cordyceps militaris to Salt Treatment During Cordycepins Production. PMID:35004818
Decreased miR-940 expression can predict a negative prognosis in early-stage nonsmoking female lung adenocarcinoma. PMID:35004257
Searching beyond the streetlight: Neonicotinoid exposure alters the neurogenomic state of worker honey bees. PMID:35003705
Identification of Keratinocyte Differentiation-Involved Genes for Metastatic Melanoma by Gene Expression Profiles. PMID:35003328
The In Vivo Transcriptomic Blueprint of Mycobacterium tuberculosis in the Lung. PMID:35003075
Genome Characteristics Reveal the Biocontrol Potential of Actinobacteria Isolated From Sugarcane Rhizosphere. PMID:35003029
Relationship Between KCNQ1 Polymorphism and Type 2 Diabetes Risk in Northwestern China. PMID:35002291
ADAMTS8 Expression is a Potential Prognostic Biomarker for Postoperative Metastasis in Lymph Node-Negative Early-Stage Invasive Breast Carcinoma Patients. PMID:35002288
oCEM: Automatic detection and analysis of overlapping co-expressed gene modules. PMID:34998362
Identification of an at-risk subpopulation with high immune infiltration based on the peroxisome pathway and TIM3 in colorectal cancer. PMID:34996408
Limb development genes underlie variation in human fingerprint patterns. PMID:34995520
Genomic profiling and expression analysis of the diacylglycerol kinase gene family in heterologous hexaploid wheat. PMID:34993014
Insight Into the Multiple Branches Traits of a Mutant in Larix olgensis by Morphological, Cytological, and Transcriptional Analyses. PMID:34992622
HESML: a real-time semantic measures library for the biomedical domain with a reproducible survey. PMID:34991460
The cold adaption profiles of Pseudoalteromonas shioyasakiensis D1497 from Yap trench to cope with cold. PMID:34987981
RNA profiles reveal signatures of future health and disease in pregnancy. PMID:34987224
Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures. PMID:34987109
Exploration the potential mechanism of the SIRT1 and its target gene FOXO1/PPARGC1A in uteropelvic junction obstruction. PMID:34984185
Inferring the genetic responses to acute drought stress across an ecological gradient. PMID:34983380
Interaction with mammalian enteric viruses alters outer membrane vesicle production and content by commensal bacteria. PMID:34981901
Structure-function relationships of the disease-linked A218T oxytocin receptor variant. PMID:34980886
Robust normalization and transformation techniques for constructing gene coexpression networks from RNA-seq data. PMID:34980209
Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer. PMID:34980144
Identification of Pueraria spp. through DNA barcoding and comparative transcriptomics. PMID:34979934
Genome-wide association studies for growth traits in broilers. PMID:34979907
Capturing the transcription factor interactome in response to sub-lethal insecticide exposure. PMID:34977825
Antigen presentation and interferon signatures in B cells driven by localized ablative cancer immunotherapy correlate with extended survival. PMID:34976205
A Novel Model of Tumor-Infiltrating B Lymphocyte Specific RNA-Binding Protein-Related Genes With Potential Prognostic Value and Therapeutic Targets in Multiple Myeloma. PMID:34976013
Metabolite and Transcriptome Profiling Analysis Revealed That Melatonin Positively Regulates Floral Scent Production in Hedychium coronarium. PMID:34975998
Preconditioning With Intermittent Hypobaric Hypoxia Attenuates Stroke Damage and Modulates Endocytosis in Residual Neurons. PMID:34975719
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping. PMID:34971560
Establishment of Human Pluripotent Stem Cell-Derived Skin Organoids Enabled Pathophysiological Model of SARS-CoV-2 Infection. PMID:34971128
Protein Function Prediction Based on PPI Networks: Network Reconstruction vs Edge Enrichment. PMID:34970299
Ultradian rhythms of AKT phosphorylation and gene expression emerge in the absence of the circadian clock components Per1 and Per2. PMID:34968386
High Expression of CEMIP Correlates Poor Prognosis and the Tumur Microenvironment in Breast Cancer as a Promisingly Prognostic Biomarker. PMID:34966410
Network pharmacology-based strategy to investigate the active ingredients and molecular mechanisms of Scutellaria Barbata D. Don against radiation pneumonitis. PMID:34964782
Bioinformatics study on different gene expression profiles of fibroblasts and vascular endothelial cells in keloids. PMID:34964740
Bioinformatics analysis of candidate genes and potential therapeutic drugs targeting adipose tissue in obesity. PMID:34964707
Mongoliitalea daihaiensis sp. nov., isolated from Daihai Lake in Inner Mongolia. PMID:34962584
CottonGen: The Community Database for Cotton Genomics, Genetics, and Breeding Research. PMID:34961276
Dichotomous Responses to Chronic Fetal Hypoxia Lead to a Predetermined Aging Phenotype. PMID:34958949
Integrated Gene Expression Profiling Analysis Reveals Potential Molecular Mechanisms and Candidate Biomarkers for Early Risk Stratification and Prediction of STEMI and Post-STEMI Heart Failure Patients. PMID:34957234
Integral Analyses of Competing Endogenous RNA Mechanisms and DNA Methylation Reveal Regulatory Mechanisms in Osteosarcoma. PMID:34957096
Combined Metabolome and Transcriptome Analyses of Young, Mature, and Old Rhizome Tissues of Zingiber officinale Roscoe. PMID:34956334
Unraveling Admixture, Inbreeding, and Recent Selection Signatures in West African Indigenous Cattle Populations in Benin. PMID:34956303
Ontology-Enriched Specifications Enabling Findable, Accessible, Interoperable, and Reusable Marine Metagenomic Datasets in Cyberinfrastructure Systems. PMID:34956127
Single-Larva RNA Sequencing Identifies Markers of Copper Toxicity and Exposure in Early Mytilus californianus Larvae. PMID:34955868
Dynamic immune response characteristics of piglets infected with Actinobacillus pleuropneumoniae through omic. PMID:34952961
A Novel Four-Gene Signature as a Potential Prognostic Biomarker for Hepatocellular Carcinoma. PMID:34950206
IgA-Dominated Humoral Immune Responses Govern Patients' Outcome in Endometrial Cancer. PMID:34949671
Limited allele-specific gene expression in highly polyploid sugarcane. PMID:34949669
GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data. PMID:34949163
Human TRMT112-Methyltransferase Network Consists of Seven Partners Interacting with a Common Co-Factor. PMID:34948388
Physiological, Biochemical and Transcriptomic Analysis of the Aerial Parts (Leaf-Blade and Petiole) of Asarum sieboldii Responding to Drought Stress. PMID:34948197
Targeted Therapy Modulates the Secretome of Cancer-Associated Fibroblasts to Induce Resistance in HER2-Positive Breast Cancer. PMID:34948097
Comparative Transcriptomics and Gene Knockout Reveal Virulence Factors of Arthrinium phaeospermum in Bambusa pervariabilis × Dendrocalamopsis grandis. PMID:34946984
Longitudinal Changes in Cortical Thickness in Adolescents with Autism Spectrum Disorder and Their Association with Restricted and Repetitive Behaviors. PMID:34946972
Analysis of Serum Biochemical Indexes, Egg Quality, and Liver Transcriptome in Laying Hens Fed Diets Supplemented with Gynostemma pentaphyllum Powder. PMID:34946891
Bioinformatic Analysis Identified Hub Genes Associated with Heterocyclic Amines Induced Cytotoxicity of Peripheral Blood Mononuclear Cells. PMID:34946837
MicroRNA Analysis of Human Stroke Brain Tissue Resected during Decompressive Craniectomy/Stroke-Ectomy Surgery. PMID:34946809
In Silico Investigation of the Biological Implications of Complex DNA Damage with Emphasis in Cancer Radiotherapy through a Systems Biology Approach. PMID:34946681
Mining the Genome of Bacillus velezensis VB7 (CP047587) for MAMP Genes and Non-Ribosomal Peptide Synthetase Gene Clusters Conferring Antiviral and Antifungal Activity. PMID:34946111
Genomic and Metabolic Features of an Unexpectedly Predominant, Thermophilic, Assistant Starter Microorganism, Thermus thermophilus, in Chinese Inner Mongolian Cheese. PMID:34945513
Transcription Factors Active in the Anterior Blastema of Schmidtea mediterranea. PMID:34944426
Comparative Transcriptomic Analysis of Regenerated Skins Provides Insights into Cutaneous Air-Breathing Formation in Fish. PMID:34943209
Full-Length Transcriptome Sequencing of the Scleractinian Coral Montipora foliosa Reveals the Gene Expression Profile of Coral-Zooxanthellae Holobiont. PMID:34943189
Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis. PMID:34941867
Mechanisms underlying Clostridium pasteurianum's metabolic shift when grown with Geobacter sulfurreducens. PMID:34939136
Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis. PMID:34938914
Gene expression and epigenetic responses of the marine Cladoceran, Evadne nordmanni, and the copepod, Acartia clausi, to elevated CO2. PMID:34938472
Extensive mitochondrial proteome disturbance occurs during the early stages of acute myocardial ischemia. PMID:34938367
Identification and Characterization of Circular RNAs in Association With the Deposition of Intramuscular Fat in Aohan Fine-Wool Sheep. PMID:34938314
Biosafety and Proteome Profiles of Different Heat Inactivation Methods for Mycobacterium tuberculosis. PMID:34937194
Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC. PMID:34932879
Identification of starch candidate genes using SLAF-seq and BSA strategies and development of related SNP-CAPS markers in tetraploid potato. PMID:34932571
Identification of Potential Genetic Biomarkers and Target Genes of Peri-Implantitis Using Bioinformatics Tools. PMID:34931168
Comparative transcriptome and DNA methylation analysis in temperature-sensitive genic male sterile wheat BS366. PMID:34930131
5-Alpha reductase inhibitors induce a prostate luminal to club cell transition in human benign prostatic hyperplasia. PMID:34928497
Effects of Serum Metabolites on the Pancreatic Transcriptome in Acute Acalculous Cholecystitis. PMID:34925503
Dual RNA-Seq Analysis of the Interaction Between Edible Fungus Morchella sextelata and Its Pathogenic Fungus Paecilomyces penicillatus Uncovers the Candidate Defense and Pathogenic Factors. PMID:34925269
Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of osteosarcoma cancer. PMID:34922489
Recurring exposure to low humidity induces transcriptional and protein level changes in the vocal folds of rabbits. PMID:34921171
Gene prediction of aging-related diseases based on DNN and Mashup. PMID:34920719
De novo transcriptome assembly and annotation of parthenogenetic lizard Darevskia unisexualis and its parental ancestors Darevskia valentini and Darevskia raddei nairensis. PMID:34917712
A Novel Single-Cell RNA Sequencing Data Feature Extraction Method Based on Gene Function Analysis and Its Applications in Glioma Study. PMID:34917514
Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling. PMID:34916903
Identification of a Lipid Metabolism-Associated Gene Signature Predicting Survival in Breast Cancer. PMID:34916832
Genome-wide identification of enhancers and transcription factors regulating the myogenic differentiation of bovine satellite cells. PMID:34915843
Genomic analysis of Elsinoë arachidis reveals its potential pathogenic mechanism and the biosynthesis pathway of elsinochrome toxin. PMID:34914789
Draft Genome Sequence of Bacillus pacificus KVCMST-8A-12, Isolated from a Marine Sediment Sample from the Kanyakumari Coast, India. PMID:34913714
Identification of Key Deregulated RNA-Binding Proteins in Pancreatic Cancer by Meta-Analysis and Prediction of Their Role as Modulators of Oncogenesis. PMID:34912796
Exploring Pathway-Based Group Lasso for Cancer Survival Analysis: A Special Case of Multi-Task Learning. PMID:34912376
The Edible Plant Microbiome represents a diverse genetic reservoir with functional potential in the human host. PMID:34911987
Transcriptome comparative analysis of ovarian follicles reveals the key genes and signaling pathways implicated in hen egg production. PMID:34911438
DNA methylation of ARHGAP30 is negatively associated with ARHGAP30 expression in lung adenocarcinoma, which reduces tumor immunity and is detrimental to patient survival. PMID:34910688
Potential Novel Modules and Hub Genes as Prognostic Candidates of Thyroid Cancer by Weighted Gene Co-Expression Network Analysis. PMID:34908870
Genome analysis provides insight into hyper-virulence of Streptococcus suis LSM178, a human strain with a novel sequence type 1005. PMID:34907269
Competitive endogenous RNA network and pathway-based analysis of LncRNA single-nucleotide polymorphism in myasthenia gravis. PMID:34907261
Metabolic drug survey highlights cancer cell dependencies and vulnerabilities. PMID:34907165
Long noncoding RNA GSEC promotes neutrophil inflammatory activation by supporting PFKFB3-involved glycolytic metabolism in sepsis. PMID:34907156
The importance of automation in genetic diagnosis: Lessons from analyzing an inherited retinal degeneration cohort with the Mendelian Analysis Toolkit (MATK). PMID:34906470
A novel strategy to uncover specific GO terms/phosphorylation pathways in phosphoproteomic data in Arabidopsis thaliana. PMID:34906086
Computational modelling of chromosomally clustering protein domains in bacteria. PMID:34906073
Relation Extraction of Protein Complexes from Dynamic Protein-Protein Interaction Network. PMID:34904064
The mining and construction of a knowledge base for gene-disease association in mitochondrial diseases. PMID:34903783
Longitudinal DNA methylation dynamics as a practical indicator in clinical epigenetics. PMID:34903243
Computational modeling of human-nCoV protein-protein interaction network. PMID:34902553
Pathway Enrichment Analysis of Microarray Data. PMID:34902127
Robust deep learning model for prognostic stratification of pancreatic ductal adenocarcinoma patients. PMID:34901786
RNA-seq dataset of subcutaneous adipose tissue: Transcriptional differences between obesity and healthy women. PMID:34901353
Time-Resolved Extracellular Matrix Atlas of the Developing Human Skin Dermis. PMID:34901026
Regeneration of Planarian Auricles and Reestablishment of Chemotactic Ability. PMID:34901022
Development of an Oxidative Phosphorylation-Related and Immune Microenvironment Prognostic Signature in Uterine Corpus Endometrial Carcinoma. PMID:34901000
Genome-wide association of single nucleotide polymorphism loci and candidate genes for frogeye leaf spot (Cercospora sojina) resistance in soybean. PMID:34895144
OmicsOne: associate omics data with phenotypes in one-click. PMID:34895137
Identification of novel biomarkers in breast cancer via integrated bioinformatics analysis and experimental validation. PMID:34895070
Analysis of a circRNA-, miRNA-, and mRNA-associated ceRNA network reveals potential biomarkers in preeclampsia a ceRNA network in preeclampsia. PMID:34894939
Bacteriostatic effects of high-intensity ultrasonic treatment on Bacillus subtilis vegetative cells. PMID:34894527
Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor. PMID:34894101
Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder. PMID:34893581
Integrated genome and tissue engineering enables screening of cancer vulnerabilities in physiologically relevant perfusable ex vivo cultures. PMID:34890975
Prediction of Hormone-Binding Proteins Based on K-mer Feature Representation and Naive Bayes. PMID:34887905
Genome-wide map of N6-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis. PMID:34887647
Meta-analyses identify DNA methylation associated with kidney function and damage. PMID:34887417
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. PMID:34887389
The N-Acetylglucosamine Kinase from Yarrowia lipolytica Is a Moonlighting Protein. PMID:34884915
Splice-Variant Knock-Out of TGFβ Receptors Perturbates the Proteome of Ovarian Carcinoma Cells. PMID:34884451
Artificial intelligence, molecular subtyping, biomarkers, and precision oncology. PMID:34881776
Circular RNA Expression and Regulation Profiling in Testicular Tissues of Immature and Mature Wandong Cattle (Bos taurus). PMID:34880896
Barcoded reciprocal hemizygosity analysis via sequencing illuminates the complex genetic basis of yeast thermotolerance. PMID:34878132
Whole-Genome Sequencing of Acer catalpifolium Reveals Evolutionary History of Endangered Species. PMID:34878129
Identifying the temporal electrophysiological and molecular changes that contribute to TSC-associated epileptogenesis. PMID:34877936
Development and Validation of a Prognostic N6-Methyladenosine-Related Immune Gene Signature for Lung Adenocarcinoma. PMID:34876833
Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis. PMID:34876074
The effect and mechanism of Jiao-tai-wan in the treatment of diabetes mellitus with depression based on network pharmacology and experimental analysis. PMID:34875999
reString: an open-source Python software to perform automatic functional enrichment retrieval, results aggregation and data visualization. PMID:34873191
Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling. PMID:34872593
Comprehensive Analysis of the Transcriptome-Wide m6A Methylation Modification Difference in Liver Fibrosis Mice by High-Throughput m6A Sequencing. PMID:34869362
Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells. PMID:34869314
Genomics Characterization of an Engineered Corynebacterium glutamicum in Bioreactor Cultivation Under Ionic Liquid Stress. PMID:34869279
Comprehensive Transcriptomic Profiling of Murine Osteoclast Differentiation Reveals Novel Differentially Expressed Genes and LncRNAs. PMID:34868271
LIMD2 is a Prognostic and Predictive Marker in Patients With Esophageal Cancer Based on a ceRNA Network Analysis. PMID:34868263
Genome-Wide Identification of Long Non-Coding RNAs and Their Potential Functions in Poplar Growth and Phenylalanine Biosynthesis. PMID:34868243
Chromosome-Scale Reference Genome of Amphicarpaea edgeworthii: A New Resource for Amphicarpic Plants Research and Complex Flowering Pattern. PMID:34868169
Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function. PMID:34867441
The Pharmacological Mechanism of Guchangzhixie Capsule Against Experimental Colitis. PMID:34867387
Quantitative Proteomic Analysis of Mouse Sciatic Nerve Reveals Post-injury Upregulation of ADP-Dependent Glucokinase Promoting Macrophage Phagocytosis. PMID:34867191
Network analytics for drug repurposing in COVID-19. PMID:34864885
VectorBase.org updates: bioinformatic resources for invertebrate vectors of human pathogens and related organisms. PMID:34864248
Statistical testing in transcriptomic-neuroimaging studies: A how-to and evaluation of methods assessing spatial and gene specificity. PMID:34862695
Identification of genes related to tipburn resistance in Chinese cabbage and preliminary exploration of its molecular mechanism. PMID:34861825
Multifaceted pathomolecular mechanism of a VWF large deletion involved in the pathogenesis of severe VWD. PMID:34861678
The chromosome-level genome provides insight into the molecular mechanism underlying the tortuous-branch phenotype of Prunus mume. PMID:34861048
Antiviral RNA interference in disease vector (Asian longhorned) ticks. PMID:34860862
Maternal immune activation downregulates schizophrenia genes in the foetal mouse brain. PMID:34859219
Expression Signatures of Long Noncoding RNAs in Left Ventricular Noncompaction. PMID:34859074
Key Markers Involved in the Anticolon Cancer Response of CD8+ T Cells through the Regulation of Cholesterol Metabolism. PMID:34858500
Comparative Transcriptome Sequencing of Taro Corm Development With a Focus on the Starch and Sucrose Metabolism Pathway. PMID:34858484
A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation. PMID:34858137
Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease. PMID:34857794
Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data. PMID:34856921
Identification of key pathways and RNAs associated with skeletal muscle atrophy after spinal cord injury. PMID:34854395
Bronchopulmonary dysplasia and wnt pathway-associated single nucleotide polymorphisms. PMID:34853430
Investigation of hub gene associated with the infection of Staphylococcus aureus via weighted gene co-expression network analysis. PMID:34852788
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation. PMID:34851693
DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation. PMID:34850135
The Tetragnatha kauaiensis Genome Sheds Light on the Origins of Genomic Novelty in Spiders. PMID:34849853
Distinct gene expression dynamics in germ line and somatic tissue during ovariole morphogenesis in Drosophila melanogaster. PMID:34849771
Synergistic alterations in the multilevel chromatin structure anchor dysregulated genes in small cell lung cancer. PMID:34849199
Integrative genome, transcriptome, microRNA, and degradome analysis of water dropwort (Oenanthe javanica) in response to water stress. PMID:34848704
Improvement of Astragalin on Spermatogenesis in Oligoasthenozoospermia Mouse Induced by Cyclophosphamide. PMID:34846706
Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation. PMID:34845225
Toll-Like Receptor (TLR) Signaling Enables Cyclic GMP-AMP Synthase (cGAS) Sensing of HIV-1 Infection in Macrophages. PMID:34844429
Epididymal mRNA and miRNA transcriptome analyses reveal important genes and miRNAs related to sperm motility in roosters. PMID:34844112
Testing biological network motif significance with exponential random graph models. PMID:34841042
Identification of Hub Gene GRIN1 Correlated with Histological Grade and Prognosis of Glioma by Weighted Gene Coexpression Network Analysis. PMID:34840971
Identification of copy number variation-driven molecular subtypes informative for prognosis and treatment in pancreatic adenocarcinoma of a Chinese cohort. PMID:34839264
Pathway Enrichment Analysis of Microarray Data Fom Human Penis of Diabetic and Peyronie's Patients, in Comparison With Diabetic Rat Erectile Dysfunction Models. PMID:34838480
The Aliment to Bodily Condition knowledgebase (ABCkb): a database connecting plants and human health. PMID:34838100
A multitask transfer learning framework for the prediction of virus-human protein-protein interactions. PMID:34837942
Exosomes produced by melanoma cells significantly influence the biological properties of normal and cancer-associated fibroblasts. PMID:34837514
Identification of transcriptomics biomarkers for the early prediction of the prognosis of septic shock from pneumopathies. PMID:34836493
Effects of Lingonberry (Vaccinium vitis-idaea L.) Supplementation on Hepatic Gene Expression in High-Fat Diet Fed Mice. PMID:34835949
Comparison of the Proteomes of Porcine Macrophages and a Stable Porcine Cell Line after Infection with African Swine Fever Virus. PMID:34835004
Transcriptome Analysis of Lolium temulentum Exposed to a Combination of Drought and Heat Stress. PMID:34834610
Broad Spectrum Antiviral Properties of Cardiotonic Steroids Used as Potential Therapeutics for Emerging Coronavirus Infections. PMID:34834252
The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts. PMID:34831777
Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae. PMID:34831396
Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5. PMID:34830489
Quantitative Analysis of the Cardiac Phosphoproteome in Response to Acute β-Adrenergic Receptor Stimulation In Vivo. PMID:34830474
Phosphoproteomic Comparison of Four Eimeria tenella Life Cycle Stages. PMID:34829991
MicroRNA Sequencing Analysis in Obstructive Sleep Apnea and Depression: Anti-Oxidant and MAOA-Inhibiting Effects of miR-15b-5p and miR-92b-3p through Targeting PTGS1-NF-κB-SP1 Signaling. PMID:34829725
The Genomic and Transcriptomic Analyses of Floccularia luteovirens, a Rare Edible Fungus in the Qinghai-Tibet Plateau, Provide Insights into the Taxonomy Placement and Fruiting Body Formation. PMID:34829176
Identification, Analysis, and Confirmation of Seed Storability-Related Loci in Dongxiang Wild Rice (Oryza rufipogon Griff.). PMID:34828437
Comparative RNA-Seq Analysis Reveals Potentially Resistance-Related Genes in Response to Bacterial Canker of Tomato. PMID:34828351
Proteomics Profiling with SWATH-MS Quantitative Analysis of Changes in the Human Brain with HIV Infection Reveals a Differential Impact on the Frontal and Temporal Lobes. PMID:34827437
Transcriptome Analysis Reveals Different Responsive Patterns to Nitrogen Deficiency in Two Wheat Near-Isogenic Lines Contrasting for Nitrogen Use Efficiency. PMID:34827119
Heterogeneous recruitment abilities to RNA polymerases generate nonlinear scaling of gene expression with cell volume. PMID:34824198
Identification of miRNA-mRNA network and immune-related gene signatures in IgA nephropathy by integrated bioinformatics analysis. PMID:34823491
Automatic consistency assurance for literature-based gene ontology annotation. PMID:34823464
SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. PMID:34822715
A roadmap for metagenomic enzyme discovery. PMID:34821235
A proposal for score assignment to characterize biological processes from mass spectral analysis of serum. PMID:34820522
Development of a bioinformatics platform for analysis of quantitative transcriptomics and proteomics data: the OMnalysis. PMID:34820180
Establishment and characterization of prostate organoids from treatment-naïve patients with prostate cancer. PMID:34820005
Development of a chemogenomics library for phenotypic screening. PMID:34819133
Quantitative dissection of multilocus pathogenic variation in an Egyptian infant with severe neurodevelopmental disorder resulting from multiple molecular diagnoses. PMID:34816580
Multiple regression analysis of a comprehensive transcriptomic data assembly elucidates mechanically- and biochemically-driven responses to focused ultrasound blood-brain barrier disruption. PMID:34815790
A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation. PMID:34815476
p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes. PMID:34813504
Inheritance of gene expression throughout fruit development in chili pepper. PMID:34811443
PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans. PMID:34807903
Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity. PMID:34805797
Whole genome sequence data of Chromobacterium violaceum WCH4, a human pathogenic strain from Sabah, Malaysia. PMID:34805463
Integrated Strategy of UHPLC-Q-TOF-MS and Molecular Networking for Identification of Diterpenoids from Euphorbia fischeriana Steud. and Prediction of the Anti-Breast-Cancer Mechanism by the Network Pharmacological Method. PMID:34804177
Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency. PMID:34804114
Selecting Hub Genes and Predicting Target Genes of microRNAs in Tuberculosis via the Bioinformatics Analysis. PMID:34803519
Analyzing differentially expressed genes and pathways of Bex2-deficient mouse lung via RNA-Seq. PMID:34803456
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. PMID:34800366
Transcriptome and metabolome analysis to reveal major genes of saikosaponin biosynthesis in Bupleurum chinense. PMID:34798822
USH2A Mutation is Associated With Tumor Mutation Burden and Antitumor Immunity in Patients With Colon Adenocarcinoma. PMID:34795697
Follicular T cells are clonally and transcriptionally distinct in B cell-driven mouse autoimmune disease. PMID:34795279
Altered cell and RNA isoform diversity in aging Down syndrome brains. PMID:34795060
APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell-Mediated Antitumor Immune Responses. PMID:34795033
Construction of a single nucleotide variant score-related gene-based prognostic model in hepatocellular carcinoma: analysis of multi-independent databases and validation in vitro. PMID:34794449
Asc-Seurat: analytical single-cell Seurat-based web application. PMID:34794383
Small RNA sequencing reveals various microRNAs involved in piperine biosynthesis in black pepper (Piper nigrum L.). PMID:34794378
A genome-wide search for determinants of survival in 1926 patients with advanced colorectal cancer with follow-up in over 22,000 patients. PMID:34794066
Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals. PMID:34793442
Concurrent Evolution of Antiaging Gene Duplications and Cellular Phenotypes in Long-Lived Turtles. PMID:34792580
CircleBase: an integrated resource and analysis platform for human eccDNAs. PMID:34792166
Avian ceca are indispensable for hindgut enteric nervous system development. PMID:34792104
Nucleolar GTPase Bms1 displaces Ttf1 from RFB-sites to balance progression of rDNA transcription and replication. PMID:34791311
The disease-associated proteins Drosophila Nab2 and Ataxin-2 interact with shared RNAs and coregulate neuronal morphology. PMID:34791182
Hypothalamic Transcriptome Analysis Reveals the Crucial MicroRNAs and mRNAs Affecting Litter Size in Goats. PMID:34790713
Six mutator-derived lncRNA signature of genome instability for predicting the clinical outcome of colon cancer. PMID:34790382
The protein-protein interaction ontology: for better representing and capturing the biological context of protein interaction. PMID:34789143
Transcriptomic profiling reveals gene expression in human peripheral blood after exposure to low-dose ionizing radiation. PMID:34788452
Glutathione, carbohydrate and other metabolites of Larix olgensis A. Henry reponse to polyethylene glycol-simulated drought stress. PMID:34788320
A Superefficient Ochratoxin A Hydrolase with Promising Potential for Industrial Applications. PMID:34788069
Undervalued Pseudo-nifH Sequences in Public Databases Distort Metagenomic Insights into Biological Nitrogen Fixers. PMID:34787447
Screening of differentially expressed miRNAs during osteogenic/odontogenic differentiation of human dental pulp stem cells exposed to mechanical stress. PMID:34786047
Multidimensional Analysis of the Role of Charged Multivesicular Body Protein 7 in Pan-Cancer. PMID:34785938
Dynamic Urinary Proteome Changes in Ovalbumin-Induced Asthma Mouse Model Using Data-Independent Acquisition Proteomics. PMID:34785909
Identification of key genes involved in recovery from spinal cord injury in adult zebrafish. PMID:34782579
Hub microRNAs and genes in the development of atrial fibrillation identified by weighted gene co-expression network analysis. PMID:34781940
Transcriptomic responses to drought stress in Polygonatum kingianum tuber. PMID:34781887
The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers. PMID:34780568
Categorizing Sequences of Concern by Function To Better Assess Mechanisms of Microbial Pathogenesis. PMID:34780277
Linking Diabetes Mellitus with Alzheimer's Disease: Bioinformatics Analysis for the Potential Pathways and Characteristic Genes. PMID:34779951
Trends in biological data integration for the selection of enzymes and transcription factors related to cellulose and hemicellulose degradation in fungi. PMID:34777932
Pairwise Biological Network Alignment Based on Discrete Bat Algorithm. PMID:34777564
Trichoderma-Induced Ethylene Responsive Factor MsERF105 Mediates Defense Responses in Malus sieversii. PMID:34777407
Novel Enzymes From the Red Sea Brine Pools: Current State and Potential. PMID:34777282
Identification of KIF4A as a prognostic biomarker for esophageal squamous cell carcinoma. PMID:34775374
Computationally Reconstructed Interactome of Bradyrhizobium diazoefficiens USDA110 Reveals Novel Functional Modules and Protein Hubs for Symbiotic Nitrogen Fixation. PMID:34769335
Distinct Exosomal miRNA Profiles from BALF and Lung Tissue of COPD and IPF Patients. PMID:34769265
Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations. PMID:34767537
Severe types of fetopathy are associated with changes in the serological proteome of diabetic mothers. PMID:34766598
Computational methods for protein localization prediction. PMID:34765098
Immune Characteristics Analysis and Transcriptional Regulation Prediction Based on Gene Signatures of Chronic Obstructive Pulmonary Disease. PMID:34764646
A data-driven framework for mapping domains of human neurobiology. PMID:34764476
Chronic pathophysiological changes in the normal brain parenchyma caused by radiotherapy accelerate glioma progression. PMID:34764346
Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation. PMID:34763026
Identification of discriminative gene-level and protein-level features associated with pathogenic gain-of-function and loss-of-function variants. PMID:34762822
Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans. PMID:34762601
Tlr2/4 Double Knockout Attenuates the Degeneration of Primary Auditory Neurons: Potential Mechanisms From Transcriptomic Perspectives. PMID:34760891
Integrative analysis of Iso-Seq and RNA-seq data reveals transcriptome complexity and differentially expressed transcripts in sheep tail fat. PMID:34760406
Contextualizing Genes by Using Text-Mined Co-Occurrence Features for Cancer Gene Panel Discovery. PMID:34759963
Dietary palmitic acid promotes a prometastatic memory via Schwann cells. PMID:34759321
Integration of transcriptomics and network analysis reveals co-expressed genes in Frankliniella occidentalis larval guts that respond to tomato spotted wilt virus infection. PMID:34758725
Web-based transcriptome analysis determines a sixteen-gene signature and associated drugs on hearing loss patients: A bioinformatics approach. PMID:34758154
IID 2021: towards context-specific protein interaction analyses by increased coverage, enhanced annotation and enrichment analysis. PMID:34755877
T2-DAG: a powerful test for differentially expressed gene pathways via graph-informed structural equation modeling. PMID:34755844
Co-evolution based machine-learning for predicting functional interactions between human genes. PMID:34753957
Network analysis reveals rare disease signatures across multiple levels of biological organization. PMID:34753928
Pyroptosis-related gene mediated modification patterns and immune cell infiltration landscapes in cutaneous melanoma to aid immunotherapy. PMID:34753832
Circ-Usp10 promotes microglial activation and induces neuronal death by targeting miRNA-152-5p/CD84. PMID:34753388
GPRuler: Metabolic gene-protein-reaction rules automatic reconstruction. PMID:34748537
The human telomeric proteome during telomere replication. PMID:34747482
Hymenoptera Genome Database: new genomes and annotation datasets for improved go enrichment and orthologue analyses. PMID:34747465
Bacterial membrane vesicles and phages in blood after consumption of lacticaseibacillus rhamnosus JB-1. PMID:34747333
Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis. PMID:34746708
Genome Instability and Long Noncoding RNA Reveal Biomarkers for Immunotherapy and Prognosis and Novel Competing Endogenous RNA Mechanism in Colon Adenocarcinoma. PMID:34746134
Identification of Gene-Set Signature in Early-Stage Hepatocellular Carcinoma and Relevant Immune Characteristics. PMID:34745960
A Novel Three-LncRNA Signature Predicting Tumor Recurrence in Nonfunctioning Pituitary Adenomas. PMID:34745223
Multi-Omics-Based Identification and Functional Characterization of Gh_A06G1257 Proves Its Potential Role in Drought Stress Tolerance in Gossypium hirsutum. PMID:34745180
Identification of Novel Kinase-Transcription Factor-mRNA-miRNA Regulatory Network in Nasopharyngeal Carcinoma by Bioinformatics Analysis. PMID:34744455
Phenotype-tissue expression and exploration (PTEE) resource facilitates the choice of tissue for RNA-seq-based clinical genetics studies. PMID:34743696
BCG vaccination and the risk of COVID 19: A possible correlation. PMID:34742127
The Rat Genome Database (RGD) facilitates genomic and phenotypic data integration across multiple species for biomedical research. PMID:34741192
Fibromine is a multi-omics database and mining tool for target discovery in pulmonary fibrosis. PMID:34741074
β-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages. PMID:34740960
Cross-platform transcriptomic profiling of the response to recombinant human erythropoietin. PMID:34737331
High-dose dexamethasone injection disordered metabolism and multiple protein kinases expression in the mouse kidney. PMID:34735568
Lymphocyte activation gene-3 is associated with programmed death-ligand 1 and programmed cell death protein 1 in small cell lung cancer. PMID:34734020
Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. PMID:34732895
Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease. PMID:34732252
Transcriptome profiling reveals the developmental regulation of NaCl-treated Forcipomyia taiwana eggs. PMID:34732124
Patch-seq of mouse DRG neurons reveals candidate genes for specific mechanosensory functions. PMID:34731626
Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency. PMID:34731163
Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans. PMID:34730513
ParsVNN: parsimony visible neural networks for uncovering cancer-specific and drug-sensitive genes and pathways. PMID:34729476
MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction. PMID:34729303
High Expression of ERK-related RASGRF2 predicts Poor prognosis in patients with Stomach Adenocarcinoma and correlates with M2 macrophage. PMID:34729119
Proteogenomic discovery of sORF-encoded peptides associated with bacterial virulence in Yersinia pestis. PMID:34728737
Bioinformatic analysis of key pathways and genes shared between endometriosis and ovarian cancer. PMID:34727222
Structure-Aware Mycobacterium tuberculosis Functional Annotation Uncloaks Resistance, Metabolic, and Virulence Genes. PMID:34726489
Transcriptome and Exome Analyses of Hepatocellular Carcinoma Reveal Patterns to Predict Cancer Recurrence in Liver Transplant Patients. PMID:34725972
Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface. PMID:34725363
Nitecap: An Exploratory Circadian Analysis Web Application. PMID:34724846
Plasmodium falciparum Calcium-Dependent Protein Kinase 4 is Critical for Male Gametogenesis and Transmission to the Mosquito Vector. PMID:34724830
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression. PMID:34723780
Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model. PMID:34722525
Single-Cell RNA Sequencing in Multiple Pathologic Types of Renal Cell Carcinoma Revealed Novel Potential Tumor-Specific Markers. PMID:34722263
Differential transcriptome analysis and identification of genes related to resistance to blight in three varieties of Bambusa pervariabilis × Dendrocalamopsis grandis. PMID:34721984
lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells. PMID:34721591
Agent Repurposing for the Treatment of Advanced Stage Diffuse Large B-Cell Lymphoma Based on Gene Expression and Network Perturbation Analysis. PMID:34721544
Viral Strain-Specific Activation of Pathogen-Associated Molecular Pattern-Triggered Immunity Enhances Symptom Severity in Broad Bean Wilt Virus 2 Infection. PMID:34721473
Drug Repurposing for Atopic Dermatitis by Integration of Gene Networking and Genomic Information. PMID:34721386
Integrating full-length transcriptomics and metabolomics reveals the regulatory mechanisms underlying yellow pigmentation in tree peony (Paeonia suffruticosa Andr.) flowers. PMID:34719694
EWAS Open Platform: integrated data, knowledge and toolkit for epigenome-wide association study. PMID:34718752
CompoDynamics: a comprehensive database for characterizing sequence composition dynamics. PMID:34718745
Complex Portal 2022: new curation frontiers. PMID:34718729
VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center. PMID:34718728
Genomics analysis of hexanoic acid exposure in Drosophila species. PMID:34718544
Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle. PMID:34717556
PANTHER: Making genome-scale phylogenetics accessible to all. PMID:34717010
Transcriptome Analysis of Zygophyllum xanthoxylum Adaptation Strategies to Phosphate Stress. PMID:34712251
Pathway-targeting gene matrix for Drosophila gene set enrichment analysis. PMID:34710184
Crowdsourcing biocuration: The Community Assessment of Community Annotation with Ontologies (CACAO). PMID:34710081
p21 produces a bioactive secretome that places stressed cells under immunosurveillance. PMID:34709885
Identification of a Prognosis-Related Risk Signature for Bladder Cancer to Predict Survival and Immune Landscapes. PMID:34708131
Foundations for a Realism-Based Ontology of Protein Aggregates. PMID:34707469
Whole-exome analysis in Tunisian Imazighen and Arabs shows the impact of demography in functional variation. PMID:34702931
Comparative genomics reveals molecular mechanisms underlying health and reproduction in cryptorchid mammals. PMID:34702182
DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia. PMID:34699692
Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci. PMID:34699533
Gene Ontology curation of the blood-brain barrier to improve the analysis of Alzheimer's and other neurological diseases. PMID:34697638
Analysing the fitness cost of antibiotic resistance to identify targets for combination antimicrobials. PMID:34697460
De novo transcriptome analysis provides insights into the salt tolerance of Podocarpus macrophyllus under salinity stress. PMID:34696735
Prioritization of Diagnostic and Prognostic Biomarkers for Lupus Nephritis Based on Integrated Bioinformatics Analyses. PMID:34692653
Genomic insights into biocontrol potential of Bacillus stercoris LJBS06. PMID:34692367
Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows. PMID:34692022
Optical Coherence Tomography Angiography Characteristics Serve as Retinal Vein Occlusion Therapeutic Biomarkers for Dexamethasone Intravitreal Implant. PMID:34691285
RabA2b Overexpression Alters the Plasma-Membrane Proteome and Improves Drought Tolerance in Arabidopsis. PMID:34691115
Arabidopsis MED18 Interaction With RNA Pol IV and V Subunit NRPD2a in Transcriptional Regulation of Plant Immune Responses. PMID:34691090
Type 2 Diabetes Modifies Skeletal Muscle Gene Expression Response to Gastric Bypass Surgery. PMID:34690929
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer. PMID:34688654
Transcriptome changes in maternal peripheral blood during term parturition mimic perturbations preceding spontaneous preterm birth†. PMID:34686873
Nkx3-1 and Fech genes might be switch genes involved in pituitary non-functioning adenoma invasiveness. PMID:34686726
Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress. PMID:34686314
Upregulation of cathepsin L gene under mild cold conditions in young Japanese male adults. PMID:34686211
Identification of Oil Palm's Consistently Upregulated Genes during Early Infections of Ganoderma boninense via RNA-Seq Technology and Real-Time Quantitative PCR. PMID:34685835
A Candidate RNAi Screen Reveals Diverse RNA-Binding Protein Phenotypes in Drosophila Flight Muscle. PMID:34685485
A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice. PMID:34684643
Microarray Analysis of Paramylon, Isolated from Euglena Gracilis EOD-1, and Its Effects on Lipid Metabolism in the Ileum and Liver in Diet-Induced Obese Mice. PMID:34684408
Evidence for Lignocellulose-Decomposing Enzymes in the Genome and Transcriptome of the Aquatic Hyphomycete Clavariopsis aquatica. PMID:34682274
Identification of Novel Endogenous Controls for qPCR Normalization in SK-BR-3 Breast Cancer Cell Line. PMID:34681026
Comparative RNA-Seq Analyses of Solenopsis japonica (Hymenoptera: Formicidae) Reveal Gene in Response to Cold Stress. PMID:34681004
Silver: Forging almost Gold Standard Datasets. PMID:34680918
Trends in the Application of "Omics" to Ecotoxicology and Stress Ecology. PMID:34680873
Are There Limits in Explainability of Prognostic Biomarkers? Scrutinizing Biological Utility of Established Signatures. PMID:34680236
Revealing Pathways Associated with Feed Efficiency and Meat Quality Traits in Slow-Growing Chickens. PMID:34679997
Hybrid Sequencing in Different Types of Goat Skeletal Muscles Reveals Genes Regulating Muscle Development and Meat Quality. PMID:34679927
Transcriptomic Analysis of Polyhexamethyleneguanidine-Induced Lung Injury in Mice after a Long-Term Recovery. PMID:34678949
IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors. PMID:34678512
Platelet proteome dynamics in hibernating 13-lined ground squirrels. PMID:34677084
Genome-wide distribution of 5hmC in the dental pulp of mouse molars and incisors. PMID:34676418
Development and Validation of a Prognostic Model of RNA-Binding Proteins in Colon Adenocarcinoma: A Study Based on TCGA and GEO Databases. PMID:34675667
Context-aware multi-token concept recognition of biological entities. PMID:34674631
Transcriptomic profiling of neonatal mouse granulosa cells reveals new insights into primordial follicle activation†. PMID:34673933
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis. PMID:34671938
An Atypical Autoinflammatory Disease Due to an LRR Domain NLRP3 Mutation Enhancing Binding to NEK7. PMID:34671876
Pan-cancer analysis of pathway-based gene expression pattern at the individual level reveals biomarkers of clinical prognosis. PMID:34671755
iMPT-FDNPL: Identification of Membrane Protein Types with Functional Domains and a Natural Language Processing Approach. PMID:34671418
Reduced expression of OXPHOS and DNA damage genes is linked to protection from microvascular complications in long-term type 1 diabetes: the PROLONG study. PMID:34671071
The translatome of neuronal cell bodies, dendrites, and axons. PMID:34670838
Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle. PMID:34669477
Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension. PMID:34669463
Screening of anti-chronic nonbacterial prostatitis activity of different extractions of the aerial part of Glycyrrhiza uralensis, and network pharmacology research. PMID:34667596
Investigation of the transcriptomic response in Atlantic salmon (Salmo salar) gill exposed to Paramoeba perurans during early onset of disease. PMID:34667245
Construction of a 5 immune-related lncRNA-based prognostic model of NSCLC via bioinformatics. PMID:34664861
Microarray analysis of hub genes and pathways in damaged cartilage tissues of knee. PMID:34664844
Loss of the wild-type KRAS allele promotes pancreatic cancer progression through functional activation of YAP1. PMID:34663879
Genetic and epigenetic characterization of posterior pituitary tumors. PMID:34661724
Bioinformatic and experimental analyses of key biomarkers in pancreatic cancer. PMID:34659505
Identification of Novel Biomarkers Related to Lung Squamous Cell Carcinoma Using Integrated Bioinformatics Analysis. PMID:34659450
Whole-Genome Sequencing and Genome-Wide Studies of Spiny Head Croaker (Collichthys lucidus) Reveals Potential Insights for Well-Developed Otoliths in the Family Sciaenidae. PMID:34659355
High-Quality Genome of the Medicinal Plant Strobilanthes cusia Provides Insights Into the Biosynthesis of Indole Alkaloids. PMID:34659312
Proteomics Reveals an Increase in the Abundance of Glycolytic and Ethanolic Fermentation Enzymes in Developing Sugarcane Culms During Sucrose Accumulation. PMID:34659289
Comprehensive landscape and interference of clonal haematopoiesis mutations for liquid biopsy: A Chinese pan-cancer cohort. PMID:34658138
Deep post-GWAS analysis identifies potential risk genes and risk variants for Alzheimer's disease, providing new insights into its disease mechanisms. PMID:34654853
Chromosome-scale assembly and high-density genetic map of the yellow drum, Nibea albiflora. PMID:34654820
A comparative analysis of differentially expressed mRNAs, miRNAs and circRNAs provides insights into the key genes involved in the high-altitude adaptation of yaks. PMID:34654374
Text mining-based word representations for biomedical data analysis and protein-protein interaction networks in machine learning tasks. PMID:34653224
Urinary extracellular vesicles: Assessment of pre-analytical variables and development of a quality control with focus on transcriptomic biomarker research. PMID:34651466
Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease. PMID:34650613
GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses. PMID:34650124
A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation. PMID:34649616
Downregulation of mitochondrial biogenesis by virus infection triggers antiviral responses by cyclic GMP-AMP synthase. PMID:34648591
Identification of candidate genes on the basis of SNP by time-lagged heat stress interactions for milk production traits in German Holstein cattle. PMID:34648531
Leveraging Experimental Strategies to Capture Different Dimensions of Microbial Interactions. PMID:34646243
TIGER: The gene expression regulatory variation landscape of human pancreatic islets. PMID:34644572
Clarifying the molecular mechanism of tomentosin‑induced antiproliferative and proapoptotic effects in human multiple myeloma via gene expression profile and genetic interaction network analysis. PMID:34643251
Integrated analysis of dysregulated microRNA and mRNA expression in intestinal epithelial cells following ethanol intoxication and burn injury. PMID:34642361
Neutrophil Pathways of Inflammation Characterize the Blood Transcriptomic Signature of Patients with Psoriasis and Cardiovascular Disease. PMID:34639156
Platelet-Released Growth Factors Induce Genes Involved in Extracellular Matrix Formation in Human Fibroblasts. PMID:34638874
Cilostazol Induces eNOS and TM Expression via Activation with Sirtuin 1/Krüppel-like Factor 2 Pathway in Endothelial Cells. PMID:34638626
Alterations in HLA Class I-Presented Immunopeptidome and Class I-Interactome upon Osimertinib Resistance in EGFR Mutant Lung Adenocarcinoma. PMID:34638461
Comparative genome characterization of Leptospira interrogans from mild and severe leptospirosis patients. PMID:34638178
LitCovid-AGAC: cellular and molecular level annotation data set based on COVID-19. PMID:34638170
A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells. PMID:34637753
POU class 2 homeobox associating factor 1 (POU2AF1) participates in abdominal aortic aneurysm enlargement based on integrated bioinformatics analysis. PMID:34637689
Transcriptomics Reveals the Putative Mycoparasitic Strategy of the Mushroom Entoloma abortivum on Species of the Mushroom Genus Armillaria. PMID:34636668
Three chromosome-level duck genome assemblies provide insights into genomic variation during domestication. PMID:34635656
SCovid: single-cell atlases for exposing molecular characteristics of COVID-19 across 10 human tissues. PMID:34634820
Metabolic gene regulation by Drosophila GATA transcription factor Grain. PMID:34634038
OnTheFly2.0: a text-mining web application for automated biomedical entity recognition, document annotation, network and functional enrichment analysis. PMID:34632381
OntoRepliCov: an Ontology-Based Approach for Modeling the SARS-CoV-2 Replication Process. PMID:34630741
Regulation of Long Non-coding RNA KCNQ1OT1 Network in Colorectal Cancer Immunity. PMID:34630508
The Biocontrol and Plant Growth-Promoting Properties of Streptomyces alfalfae XN-04 Revealed by Functional and Genomic Analysis. PMID:34630371
Effects of Bacille Calmette Guerin (BCG) vaccination during COVID-19 infection. PMID:34624759
Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet. PMID:34624333
Clustering Spatial Transcriptomics Data. PMID:34623423
mRNA Network: Solution for Tracking Chemotherapy Insensitivity in Small-Cell Lung Cancer. PMID:34621500
A Taxon-Wise Insight Into Rock Weathering and Nitrogen Fixation Functional Profiles of Proglacial Systems. PMID:34621246
An overview of machine learning methods for monotherapy drug response prediction. PMID:34619752
Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq. PMID:34618841
Phenotyping stomatal closure by thermal imaging for GWAS and TWAS of water use efficiency-related genes. PMID:34618072
Neuronal activity regulates the nuclear proteome to promote activity-dependent transcription. PMID:34617965
Construction of competing endogenous RNA interaction network as prognostic markers in metastatic melanoma. PMID:34616613
Whole Genome Sequence of Alternaria alternata, the Causal Agent of Black Spot of Kiwifruit. PMID:34616379
Identification of candidate genes from androgenic gland in Macrobrachium nipponense regulated by eyestalk ablation. PMID:34615913
Genome and transcriptome analysis to understand the role diversification of cytochrome P450 gene under excess nitrogen treatment. PMID:34615481
Host genetic factors associated with the range limit of a European hantavirus. PMID:34614264
CyanoOmicsDB: an integrated omics database for functional genomic analysis of cyanobacteria. PMID:34614159
A metric for evaluating biological information in gene sets and its application to identify co-expressed gene clusters in PBMC. PMID:34613979
An updated SYSCILIA gold standard (SCGSv2) of known ciliary genes, revealing the vast progress that has been made in the cilia research field. PMID:34613793
Estrogen Hormone Is an Essential Sex Factor Inhibiting Inflammation and Immune Response in COVID-19. PMID:34611658
Aberrantly reduced expression of miR-342-5p contributes to CCND1-associated chronic myeloid leukemia progression and imatinib resistance. PMID:34611140
Genome-wide associations for immune traits in two maternal pig lines. PMID:34610786
Proteomics changes after negative pressure wound therapy in diabetic foot ulcers. PMID:34608502
A Chinese host genetic study discovered IFNs and causality of laboratory traits on COVID-19 severity. PMID:34608450
Seed sequence polymorphism rs2168518 and allele-specific target gene regulation of hsa-miR-4513. PMID:34605899
Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope. PMID:34605406
Transcriptomic Analysis Reveals a Sex-Dimorphic Influence of GAT-2 on Murine Liver Function. PMID:34604287
Antigen Presenting Cells Link the Female Genital Tract Microbiome to Mucosal Inflammation, With Hormonal Contraception as an Additional Modulator of Inflammatory Signatures. PMID:34604114
Genetic Analysis of Heterosis for Yield Influencing Traits in Brassica juncea Using a Doubled Haploid Population and Its Backcross Progenies. PMID:34603351
Genome-Wide Transcriptional Changes of Rhodosporidium kratochvilovae at Low Temperature. PMID:34603256
Integrated bioinformatics analysis of core regulatory elements involved in keloid formation. PMID:34600545
Neurogenomic divergence during speciation by reinforcement of mating behaviors in chorus frogs (Pseudacris). PMID:34600496
Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. PMID:34599810
Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer. PMID:34599169
Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line. PMID:34599159
Quantitative phosphoproteomics reveals GSK3A substrate network is involved in the cryodamage of sperm motility. PMID:34596222
X-Ray Causes mRNA Transcripts Change to Enhance Orai2-Mediated Ca2+ Influx in Rat Brain Microvascular Endothelial Cells. PMID:34595206
The Interactions of Small Proline-Rich Proteins with Late Cornified Envelope Proteins are Involved in the Pathogenesis of Psoriasis. PMID:34594126
In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes. PMID:34593953
Dramatic transcriptomic differences in Macaca mulatta and Macaca fascicularis with Plasmodium knowlesi infections. PMID:34593836
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. PMID:34592166
Interpretation of cancer mutations using a multiscale map of protein systems. PMID:34591613
Transcriptional Landscapes of Long Non-coding RNAs and Alternative Splicing in Pyricularia oryzae Revealed by RNA-Seq. PMID:34589103
Subtypes of schizophrenia identified by multi-omic measures associated with dysregulated immune function. PMID:34588622
Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway. PMID:34588580
Divergent patterns of selection on metabolite levels and gene expression. PMID:34587900
Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy: Development of PLN-R14del-Related Cardiomyopathy. PMID:34587756
The Euscaphis japonica genome and the evolution of malvids. PMID:34587334
Isolation, characterization, and genome assembly of Barnettozyma botsteinii sp. nov. and novel strains of Kurtzmaniella quercitrusa isolated from the intestinal tract of the termite Macrotermes bellicosus. PMID:34586397
Whole-genome assembly of Ganoderma leucocontextum (Ganodermataceae, Fungi) discovered from the Tibetan Plateau of China. PMID:34586388
The genome of the naturally evolved obesity-prone Ossabaw miniature pig. PMID:34585119
Transcriptomic profile of leg muscle during early growth and development in Haiyang yellow chicken. PMID:34584942
Identical twins carry a persistent epigenetic signature of early genome programming. PMID:34584077
Activity of the mouse Notch ligand DLL1 is sensitive to C-terminal tagging in vivo. PMID:34583743
Genome-wide association study and transcriptome of olecranon-type traits in peach (Prunus persica L.) germplasm. PMID:34583632
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity. PMID:34582749
Integrative proteome analysis implicates aberrant RNA splicing in impaired developmental potential of aged mouse oocytes. PMID:34582091
Dynamics of TCR repertoire and T cell function in COVID-19 convalescent individuals. PMID:34580278
Wnt pathway-related three-mRNA clinical outcome signature in bladder urothelial carcinoma: computational biology and experimental analyses. PMID:34579753
Morphological, physiological, and transcriptional responses to low nitrogen stress in Populus deltoides Marsh. clones with contrasting nitrogen use efficiency. PMID:34579659
Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2) Promotes M1 Repolarization of Porcine Alveolar Macrophages and Th1 Type Response. PMID:34579246
Quantitative Proteomics and Phosphoproteomics Reveal TNF-α-Mediated Protein Functions in Hepatocytes. PMID:34576943
Comprehensive Survey of Recent Drug Discovery Using Deep Learning. PMID:34576146
Identification of FadT as a Novel Quorum Quenching Enzyme for the Degradation of Diffusible Signal Factor in Cupriavidus pinatubonensis Strain HN-2. PMID:34576026
Complete Genomic Characterization and Identification of Saccharomycopsisphalluae sp. nov., a Novel Pathogen Causes Yellow Rot Disease on Phallus rubrovolvatus. PMID:34575745
Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells. PMID:34575486
Identification of Long Non-Coding RNAs Involved in Porcine Fat Deposition Using Two High-Throughput Sequencing Methods. PMID:34573356
Identifying GPSM Family Members as Potential Biomarkers in Breast Cancer: A Comprehensive Bioinformatics Analysis. PMID:34572330
Distinct gene-set burden patterns underlie common generalized and focal epilepsies. PMID:34571366
scMethBank: a database for single-cell whole genome DNA methylation maps. PMID:34570235
Changes in the Gut Microbiome Contribute to the Development of Behcet's Disease via Adjuvant Effects. PMID:34568329
Profiling of MicroRNAs in Midguts of Plutella xylostella Provides Novel Insights Into the Bacillus thuringiensis Resistance. PMID:34567090
Identification of a miRNA-mRNA Regulatory Networks in Placental Tissue Associated With Tibetan High Altitude Adaptation. PMID:34567059
Viral suppressor of RNA silencing in vascular plants also interferes with the development of the bryophyte Physcomitrella patens. PMID:34564869
Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers. PMID:34563241
PANNZER-A practical tool for protein function prediction. PMID:34562305
Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome. PMID:34561431
Challenges and opportunities in the study of extracellular vesicles: Global institutional context and national state of the art. PMID:34559503
Transcriptome repository of North-Western Himalayan endangered medicinal herbs: a paramount approach illuminating molecular perspective of phytoactive molecules and secondary metabolism. PMID:34557965
Transcriptomic Analysis of Short/Branched-Chain Acyl-Coenzyme a Dehydrogenase Knocked Out bMECs Revealed Its Regulatory Effect on Lipid Metabolism. PMID:34557544
LncRNA SNHG17 Contributes to Proliferation, Migration, and Poor Prognosis of Hepatocellular Carcinoma. PMID:34557456
Expression and prognosis of CDC45 in cervical cancer based on the GEO database. PMID:34557356
Transcriptome and Oxylipin Profiling Joint Analysis Reveals Opposite Roles of 9-Oxylipins and Jasmonic Acid in Maize Resistance to Gibberella Stalk Rot. PMID:34557211
Glycolysis-related gene expression profiling serves as a novel prognosis risk predictor for human hepatocellular carcinoma. PMID:34556750
Network neighbors of viral targets and differentially expressed genes in COVID-19 are drug target candidates. PMID:34556735
Examination of Gene Loss in the DNA Mismatch Repair Pathway and Its Mutational Consequences in a Fungal Phylum. PMID:34554246
Characterization of Mesenchymal Stem Cells Derived from Bisphosphonate-Related Osteonecrosis of the Jaw Patients' Gingiva. PMID:34553308
The role of metadata in reproducible computational research. PMID:34553169
A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability. PMID:34552092
Subcellular proteomics. PMID:34549195
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma. PMID:34545084
Automated conceptual model clustering: a relator-centric approach. PMID:34539311
KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases. PMID:34537014
Genetic dissection of complex traits using hierarchical biological knowledge. PMID:34534210
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network. PMID:34533192
Role of competitive endogenous RNA networks in the pathogenesis of coronary artery disease. PMID:34532371
Identifying the dynamic gene regulatory network during latent HIV-1 reactivation using high-dimensional ordinary differential equations. PMID:34531927
Identification of Novel Gene Signatures using Next-Generation Sequencing Data from COVID-19 Infection Models: Focus on Neuro-COVID and Potential Therapeutics. PMID:34531741
Cell-specific gene association network construction from single-cell RNA sequence. PMID:34530677
Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF. PMID:34529751
Prognostic impact of a lymphocyte activation-associated gene signature in GBM based on transcriptome analysis. PMID:34527446
Integrative Analysis of the Roles of lncRNAs and mRNAs in Itaconate-Mediated Protection Against Liver Ischemia-Reperfusion Injury in Mice. PMID:34526799
Understanding Competitive Endogenous RNA Network Mechanism in Type 1 Diabetes Mellitus Using Computational and Bioinformatics Approaches. PMID:34526791
Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo. PMID:34525376
MULocDeep: A deep-learning framework for protein subcellular and suborganellar localization prediction with residue-level interpretation. PMID:34522290
Bioinformatics analysis identified shared differentially expressed genes as potential biomarkers for Hashimoto's thyroiditis-related papillary thyroid cancer. PMID:34522174
Integrated analysis of the molecular mechanisms in idiopathic pulmonary fibrosis. PMID:34522168
Characterization of m6A-Related Genes Landscape in Skin Cutaneous Melanoma to Aid Immunotherapy and Assess Prognosis. PMID:34522131
Rapid Macrosatellite Evolution Promotes X-Linked Hybrid Male Sterility in a Feline Interspecies Cross. PMID:34519828
Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. PMID:34516901
Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences. PMID:34516545
SynWiki: Functional annotation of the first artificial organism Mycoplasma mycoides JCVI-syn3A. PMID:34515387
Bioinformatic analysis for potential biological processes and key targets of heart failure-related stroke. PMID:34514752
SCISSOR™: a single-cell inferred site-specific omics resource for tumor microenvironment association study. PMID:34514416
Effect of Tension on Human Periodontal Ligament Cells: Systematic Review and Network Analysis. PMID:34513810
Circulating microRNAs in Early Breast Cancer Patients and Its Association With Lymph Node Metastases. PMID:34513655
Protein function prediction with gene ontology: from traditional to deep learning models. PMID:34513334
Integrative analysis reveals clinically relevant molecular fingerprints in pancreatic cancer. PMID:34513290
Analysis of the Genome Sequence of Strain GiC-126 of Gloeostereum incarnatum with Genetic Linkage Map. PMID:34512084
Integrated analysis of lncRNA and mRNA in liver of Megalobrama amblycephala post Aeromonas hydrophila infection. PMID:34511071
Chromosomal neighbourhoods allow identification of organ specific changes in gene expression. PMID:34506480
Inferring Functional Epigenetic Modules by Integrative Analysis of Multiple Heterogeneous Networks. PMID:34504516
The Cancer Epitope Database and Analysis Resource: A Blueprint for the Establishment of a New Bioinformatics Resource for Use by the Cancer Immunology Community. PMID:34504503
Chondrocytes from Osteoarthritis Patients Adopt Distinct Phenotypes in Response to Central TH1/TH2/TH17 Cytokines. PMID:34502384
Investigating the Molecular Processes behind the Cell-Specific Toxicity Response to Titanium Dioxide Nanobelts. PMID:34502343
Classification and Treatment of Diseases in the Age of Genome Medicine Based on Pathway Pathology. PMID:34502326
Catalyzing Knowledge-Driven Discovery in Environmental Health Sciences through a Community-Driven Harmonized Language. PMID:34501574
Construction and analysis of a novel ferroptosis-related gene signature predicting prognosis in lung adenocarcinoma. PMID:34499810
A high-quality chromosome-level genome of wild Rosa rugosa. PMID:34499118
Specifying who delivers behaviour change interventions: development of an Intervention Source Ontology. PMID:34497878
Basement membrane proteins in various arterial beds from individuals with and without type 2 diabetes mellitus: a proteome study. PMID:34496837
An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information. PMID:34496745
Single-cell heterogeneity analysis and CRISPR screens in MIN6 cell line reveal transcriptional regulators of insulin. PMID:34494921
Weakly activated core inflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease. PMID:34494019
Integrative Analyses of Genes Associated with Hashimoto's Thyroiditis. PMID:34493981
Marine natural products targeting the eukaryotic cell membrane. PMID:34493848
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk. PMID:34493831
Comparative analysis of the complete mitochondrial genome sequences and anther development cytology between maintainer and Ogura-type cytoplasm male-sterile cabbage (B. oleracea Var. capitata). PMID:34493212
Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation. PMID:34491912
Integrative Analysis of Minichromosome Maintenance Proteins and Their Prognostic Significance in Melanoma. PMID:34490114
Interpretable, Scalable, and Transferrable Functional Projection of Large-Scale Transcriptome Data Using Constrained Matrix Decomposition. PMID:34490045
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis. PMID:34489600
Learning interpretable cellular and gene signature embeddings from single-cell transcriptomic data. PMID:34489404
The genome sequence provides insights into salt tolerance of Achnatherum splendens (Gramineae), a constructive species of alkaline grassland. PMID:34487631
Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids. PMID:34487490
Proteomic Analysis of Copper Toxicity in Human Fungal Pathogen Cryptococcus neoformans. PMID:34485169
Inflammatory gene expression profiling in peripheral blood from patients with Alzheimer's disease reveals key pathways and hub genes with potential diagnostic utility: a preliminary study. PMID:34484988
Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells. PMID:34484348
Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data. PMID:34483940
Centromere protein E as a novel biomarker and potential therapeutic target for retinoblastoma. PMID:34482803
Identification of anti-horn fly vaccine antigen candidates using a reverse vaccinology approach. PMID:34479607
FORUM: Building a Knowledge Graph from public databases and scientific literature to extract associations between chemicals and diseases. PMID:34478489
Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration. PMID:34475534
Human melanocyte development and melanoma dedifferentiation at single-cell resolution. PMID:34475532
A prelude to the proximity interaction mapping of CXXC5. PMID:34475492
Evolutionary history of two rare endemic conifer species from the eastern Qinghai-Tibet Plateau. PMID:34472580
Assembling stable syntrophic Escherichia coli communities by comprehensively identifying beneficiaries of secreted goods. PMID:34469744
Differential transcript usage analysis of bulk and single-cell RNA-seq data with DTUrtle. PMID:34469510
Nesterenkonia ebinurensis sp. nov., a Novel Actinobacterium Isolated From Populus euphratica. PMID:34468853
Human genetic analyses of organelles highlight the nucleus in age-related trait heritability. PMID:34467851
Chromosome-scale assembly of the Dendrobium chrysotoxum genome enhances the understanding of orchid evolution. PMID:34465765
Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment. PMID:34465370
Upper airway gene expression reveals a more robust innate and adaptive immune response to SARS-CoV-2 in children compared with older adults. PMID:34462739
Deep learning from HE slides predicts the clinical benefit from adjuvant chemotherapy in hormone receptor-positive breast cancer patients. PMID:34462515
Host metabolic shift during systemic Salmonella infection revealed by comparative proteomics. PMID:34461813
Heparanase is a novel biomarker for immune infiltration and prognosis in breast cancer. PMID:34461608
A multi-objective genetic algorithm to find active modules in multiplex biological networks. PMID:34460810
A Birds-Eye (Re)View of Acid-Suppression Drugs, COVID-19, and the Highly Variable Literature. PMID:34456726
Will Plant Genome Editing Play a Decisive Role in "Quantum-Leap" Improvements in Crop Yield to Feed an Increasing Global Human Population? PMID:34451712
Microvesicles transfer mitochondria and increase mitochondrial function in brain endothelial cells. PMID:34450196
The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort. PMID:34449791
A Comprehensive Guide to Potato Transcriptome Assembly. PMID:34448160
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters. PMID:34447313
Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review. PMID:34447243
Identification of key proteins in the signaling crossroads between wound healing and cancer hallmark phenotypes. PMID:34446793
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity. PMID:34446728
Human reference gut microbiome catalog including newly assembled genomes from under-represented Asian metagenomes. PMID:34446072
Differential Retinal Protein Expression in Primary and Secondary Retinal Ganglion Cell Degeneration Identified by Integrated SWATH and Target-Based Proteomics. PMID:34445296
Hepatic Proteomic Analysis of Selenoprotein T Knockout Mice by TMT: Implications for the Role of Selenoprotein T in Glucose and Lipid Metabolism. PMID:34445217
Metatranscriptomic Analysis of Bacterial Communities on Laundered Textiles: A Pilot Case Study. PMID:34442670
Evaluating, Filtering and Clustering Genetic Disease Cohorts Based on Human Phenotype Ontology Data with Cohort Analyzer. PMID:34442375
JDSNMF: Joint Deep Semi-Non-Negative Matrix Factorization for Learning Integrative Representation of Molecular Signals in Alzheimer's Disease. PMID:34442330
Transcriptional Profiles of Diploid Mutant Apis mellifera Embryos after Knockout of csd by CRISPR/Cas9. PMID:34442270
A Genome-Wide Association Study on Liver Stiffness Changes during Hepatitis C Virus Infection Cure. PMID:34441435
DNA Methylation Alterations in Blood Cells of Toddlers with Down Syndrome. PMID:34440289
Comparative Transcriptomic Analysis Reveals the Effects of Drought on the Biosynthesis of Methyleugenol in Asarum sieboldii Miq. PMID:34439899
Application of Weighted Gene Coexpression Network Analysis to Identify Key Modules and Hub Genes in Systemic Juvenile Idiopathic Arthritis. PMID:34435051
Establishment of a ferroptosis-related gene signature for prognosis in lung adenocarcinoma patients. PMID:34434660
Ferroptosis-Related Genes in Lung Adenocarcinoma: Prognostic Signature and Immune, Drug Resistance, Mutation Analysis. PMID:34434214
A high-resolution temporal atlas of the SARS-CoV-2 translatome and transcriptome. PMID:34433827
Integrative analysis of metabolome and transcriptome profiles provides insight into the fruit pericarp pigmentation disorder caused by 'Candidatus Liberibacter asiaticus' infection. PMID:34433413
CANVS: an easy-to-use application for the analysis and visualization of mass spectrometry-based protein-protein interaction/association data. PMID:34432510
Depletion of TAX1BP1 Amplifies Innate Immune Responses during Respiratory Syncytial Virus Infection. PMID:34431698
Bacterial surface properties influence the activity of the TAT-RasGAP317-326 antimicrobial peptide. PMID:34430812
Transcriptional Analysis of Liver Tissue Identifies Distinct Phenotypes of Indeterminate Pediatric Acute Liver Failure. PMID:34430782
Plasma proteomic profiling reveals biomarkers associated with aortic dilation in patients with bicuspid aortic valve. PMID:34430623
Identification of new target proteins of a Urotensin-II receptor antagonist using transcriptome-based drug repositioning approach. PMID:34429474
Discovery of Cellular RhoA Functions by the Integrated Application of Gene Set Enrichment Analysis. PMID:34429388
Perturbed transcriptional profiles after chronic low dose rate radiation in mice. PMID:34428250
Identification of fibronectin 1 (FN1) and complement component 3 (C3) as immune infiltration-related biomarkers for diabetic nephropathy using integrated bioinformatic analysis. PMID:34424825
C-X-C motif chemokine ligand 12: a potential therapeutic target in Duchenne muscular dystrophy. PMID:34424816
Hypoxia-Inducible Factor 2-Alpha Mediated Gene Sets Differentiate Pulmonary Arterial Hypertension. PMID:34422822
TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL. PMID:34422820
CD86 Molecule Might Be a Novel Immune-Related Prognostic Biomarker for Patients With Bladder Cancer by Bioinformatics and Experimental Assays. PMID:34422632
Systematic Analysis Identifies a Specific RNA-Binding Protein-Related Gene Model for Prognostication and Risk-Adjustment in HBV-Related Hepatocellular Carcinoma. PMID:34422009
Long Non-coding RNA RP11-395G23.3 Acts as a Competing Endogenous RNA of miR-124-3p to Regulate ROR1 in Anaplastic Thyroid Carcinoma. PMID:34421987
Activation of FcRn Mediates a Primary Resistance Response to Sorafenib in Hepatocellular Carcinoma by Single-Cell RNA Sequencing. PMID:34421602
Identifying causal models between genetically regulated methylation patterns and gene expression in healthy colon tissue. PMID:34419169
Identification of significant alteration genes, pathways and TFs induced by LPS in ARDS via bioinformatical analysis. PMID:34418997
Comparative transcriptomic analyses of glucosinolate metabolic genes during the formation of Chinese kale seeds. PMID:34418959
Use of Network Pharmacology to Investigate the Mechanism of the Compound Xuanju Capsule in the Treatment of Rheumatoid Arthritis. PMID:34414237
Dynamic Patterns of N6-Methyladenosine Profiles of Messenger RNA Correlated with the Cardiomyocyte Regenerability during the Early Heart Development in Mice. PMID:34413927
Utilization of Transcriptome, Small RNA, and Degradome Sequencing to Provide Insights Into Drought Stress and Rewatering Treatment in Medicago ruthenica. PMID:34413864
Pathogenic variations in Germ Cell Nuclear Acidic Peptidase (GCNA) are associated with human male infertility. PMID:34413498
RNA-Seq, physiological, and biochemical analysis of burley tobacco response to nitrogen deficiency. PMID:34413327
Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. PMID:34412594
Dietary omega-3 fatty acid intake impacts peripheral blood DNA methylation -anti-inflammatory effects and individual variability in a pilot study. PMID:34411715
Cadherin and Wnt signaling pathways as key regulators in diabetic nephropathy. PMID:34411124
Modeling the effects of EMT-immune dynamics on carcinoma disease progression. PMID:34408236
Gene expression profile analysis of gallic acid-induced cell death process. PMID:34408198
PhenoDB, GeneMatcher and VariantMatcher, tools for analysis and sharing of sequence data. PMID:34407837
Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro. PMID:34404774
Evaluation of the molecular response of corpora lutea to manganese-amino acid complex supplementation in gilts. PMID:34402900
Gentamicin-induced hearing loss: A retrospective study using the Food and Drug Administration Adverse Event Reporting System and a toxicological study using drug-gene network analysis. PMID:34401547
MiR-508-3p promotes proliferation and inhibits apoptosis of middle ear cholesteatoma cells by targeting PTEN/PI3K/AKT pathway. PMID:34400892
A systematic comparison of data- and knowledge-driven approaches to disease subtype discovery. PMID:34396389
Deciphering the Therapeutic Mechanisms of Wuzi Ershen Decoction in Treating Oligoasthenozoospermia through the Network Pharmacology Approach. PMID:34394386
Genes and Pathways Affecting Sheep Productivity Traits: Genetic Parameters, Genome-Wide Association Mapping, and Pathway Enrichment Analysis. PMID:34394196
Insights from the cDNA and EST analysis of Antrodia cinnamomea. PMID:34393425
Employing bioinformatics analysis to identify hub genes and microRNAs involved in colorectal cancer. PMID:34390411
Comparison of gene expression in the red imported fire ant (Solenopsis invicta) under different temperature conditions. PMID:34389756
A single amino acid residue substitution in BraA04g017190.3C, a histone methyltransferase, results in premature bolting in Chinese cabbage (Brassica rapa L. ssp. Pekinensis). PMID:34388969
Mapping gene and gene pathways associated with coronary artery disease: a CARDIoGRAM exome and multi-ancestry UK biobank analysis. PMID:34385509
Comprior: facilitating the implementation and automated benchmarking of prior knowledge-based feature selection approaches on gene expression data sets. PMID:34384353
Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function. PMID:34381982
Data on the first functionally-annotated de novo transcriptome assembly for North American flying squirrels (genus Glaucomys). PMID:34381854
Exploring tissue architecture using spatial transcriptomics. PMID:34381231
Molecular and functional characterization of detrusor PDGFRα positive cells in spinal cord injury-induced detrusor overactivity. PMID:34381120
Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children. PMID:34381049
GraphDTI: A robust deep learning predictor of drug-target interactions from multiple heterogeneous data. PMID:34380569
De novo genome assembly of the potent medicinal plant Rehmannia glutinosa using nanopore technology. PMID:34377362
A Novel miRNA-mRNA Axis Involves in Regulating Transcriptional Disorders in Pancreatic Adenocarcinoma. PMID:34377019
SERPINH1, Targeted by miR-29b, Modulated Proliferation and Migration of Human Retinal Endothelial Cells Under High Glucose Conditions. PMID:34377003
The molecular basis, genetic control and pleiotropic effects of local gene co-expression. PMID:34376650
From a genome assembly to full regulatory network prediction: the case study of Rhodotorula toruloides putative Haa1-regulon. PMID:34376148
Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver. PMID:34375333
Identification of m6A-Related Biomarkers Associated with Prognosis of Colorectal Cancer. PMID:34373442
Identifying potential association on gene-disease network via dual hypergraph regularized least squares. PMID:34372777
CAD Genes: Genome-Wide Identification, Evolution, and Their Contribution to Lignin Biosynthesis in Pear (Pyrus bretschneideri). PMID:34371647
Exploring Chemical Information in PubChem. PMID:34370395
Transcriptional Profiling of Exosomes Derived from Staphylococcus aureus-Infected Bovine Mammary Epithelial Cell Line MAC-T by RNA-Seq Analysis. PMID:34367468
Limitations of Explainability for Established Prognostic Biomarkers of Prostate Cancer. PMID:34367234
Transcriptome and Small RNA Combined Sequencing Analysis of Cold Tolerance in Non-heading Chinese Cabbage. PMID:34367230
IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming. PMID:34367159
Quantitative Peptidomics of Mouse Brain After Infection With Cyst-Forming Toxoplasma gondii. PMID:34367142
Hanseniaspora smithiae sp. nov., a Novel Apiculate Yeast Species From Patagonian Forests That Lacks the Typical Genomic Domestication Signatures for Fermentative Environments. PMID:34367085
An Ontology-Based Framework for Psychological Monitoring in Education During the COVID-19 Pandemic. PMID:34366992
Transcriptome analysis of differentially expressed genes in chrysanthemum MET1 RNA interference lines. PMID:34366589
TACR2 is associated with the immune microenvironment and inhibits migration and proliferation via the Wnt/β-catenin signaling pathway in prostate cancer. PMID:34364377
Sustained expression of inflammatory monocytes and activated T cells in COVID-19 patients and recovered convalescent plasma donors. PMID:34363351
Collagen fiber orientation disorder from H&E images is prognostic for early stage breast cancer: clinical trial validation. PMID:34362928
MAIT cells regulate NK cell-mediated tumor immunity. PMID:34362900
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma. PMID:34362313
Regulatory Network Analysis in Estradiol-Treated Human Endothelial Cells. PMID:34360960
Identification of Rhythmically Expressed LncRNAs in the Zebrafish Pineal Gland and Testis. PMID:34360576
Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways. PMID:34359976
Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profiles in Testes of Calves and Sexually Mature Wandong Bulls (Bos taurus). PMID:34359134
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast. PMID:34358317
Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses. PMID:34357354
The USDA-ARS Ag100Pest Initiative: High-Quality Genome Assemblies for Agricultural Pest Arthropod Research. PMID:34357286
Computational Probing the Methylation Sites Related to EGFR Inhibitor-Responsive Genes. PMID:34356665
Male Differentiation in the Marine Copepod Oithona nana Reveals the Development of a New Nervous Ganglion and Lin12-Notch-Repeat Protein-Associated Proteolysis. PMID:34356512
A Reassessment of Copy Number Variations in Congenital Heart Defects: Picturing the Whole Genome. PMID:34356064
Identification of Hub Genes Associated with Diabetes Mellitus and Tuberculosis Using Bioinformatic Analysis. PMID:34354368
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids. PMID:34354063
Personalized single-cell networks: a framework to predict the response of any gene to any drug for any patient. PMID:34353329
Evaluating whole-genome expression differences in idiopathic and diabetic adhesive capsulitis. PMID:34352401
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function. PMID:34350936
Network Pharmacology Combined with Bioinformatics to Investigate the Mechanisms and Molecular Targets of Astragalus Radix-Panax notoginseng Herb Pair on Treating Diabetic Nephropathy. PMID:34349833
Genomic Analysis of the Mycoparasite Pestalotiopsis sp. PG52. PMID:34349810
Revealing protein-protein interactions at the transcriptome scale by sequencing. PMID:34348091
Ubiquitination-Related miRNA-mRNA Interaction Is a Potential Mechanism in the Progression of Retinoblastoma. PMID:34347012
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity. PMID:34344941
Effects of low lead exposure on sperm quality and sperm DNA methylation in adult men. PMID:34344450
Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2. PMID:34343211
Comprehensive Strain-Level Analysis of the Gut Microbe Faecalibacterium prausnitzii in Patients with Liver Cirrhosis. PMID:34342541
DeepMAge: A Methylation Aging Clock Developed with Deep Learning. PMID:34341706
Identifying molecular insight of synergistic complexities for SARS-CoV-2 infection with pre-existing type 2 diabetes. PMID:34340124
A systems-level study reveals host-targeted repurposable drugs against SARS-CoV-2 infection. PMID:34339582
Developmental lineage of human pluripotent stem cell-derived cardiac fibroblasts affects their functional phenotype. PMID:34339055
Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma. PMID:34336638
Comparative Transcriptome and Weighted Gene Co-expression Network Analysis Identify Key Transcription Factors of Rosa chinensis 'Old Blush' After Exposure to a Gradual Drought Stress Followed by Recovery. PMID:34335694
Comparing Host Module Activation Patterns and Temporal Dynamics in Infection by Influenza H1N1 Viruses. PMID:34335598
Genome-wide profiles of UV lesion susceptibility, repair, and mutagenic potential in melanoma. PMID:34333390
Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors. PMID:34332577
Computational identification of repurposed drugs against viruses causing epidemics and pandemics via drug-target network analysis. PMID:34332351
Global patterns of enhancer activity during sea urchin embryogenesis assessed by eRNA profiling. PMID:34330790
Epigenetic Analysis of the Chromatin Landscape Identifies a Repertoire of Murine Eosinophil-Specific PU.1-Bound Enhancers. PMID:34330753
Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis. PMID:34330317
Spectrum of Protein Location in Proteomes Captures Evolutionary Relationship Between Species. PMID:34328525
Clinical Genetic Risk Variants Inform a Functional Protein Interaction Network for Tetralogy of Fallot. PMID:34328347
Exosomal miR-218-5p/miR-363-3p from Endothelial Progenitor Cells Ameliorate Myocardial Infarction by Targeting the p53/JMY Signaling Pathway. PMID:34326916
Comparative transcriptome analysis reveals regulatory network and regulators associated with proanthocyanidin accumulation in persimmon. PMID:34325657
Genetic mapping of renal glutathione suggests a novel regulatory locus on the murine X chromosome and overlap with hepatic glutathione regulation. PMID:34324982
Transcriptional Profiling During Neural Conversion. PMID:34324187
Eukaryotic initiation factor EIF-3.G augments mRNA translation efficiency to regulate neuronal activity. PMID:34323215
Proteomic analysis reveals dexamethasone rescues matrix breakdown but not anabolic dysregulation in a cartilage injury model. PMID:34322675
Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer. PMID:34322485
Genome Size Estimation and Full-Length Transcriptome of Sphingonotus tsinlingensis: Genetic Background of a Drought-Adapted Grasshopper. PMID:34322153
Gene expression profile of the murine ischemic retina and its response to Aflibercept (VEGF-Trap). PMID:34321516
Two Reference-Quality Sea Snake Genomes Reveal Their Divergent Evolution of Adaptive Traits and Venom Systems. PMID:34320652
RCA2: a scalable supervised clustering algorithm that reduces batch effects in scRNA-seq data. PMID:34320202
DTI-Voodoo: machine learning over interaction networks and ontology-based background knowledge predicts drug-target interactions. PMID:34320178
Functionathon: a manual data mining workflow to generate functional hypotheses for uncharacterized human proteins and its application by undergraduate students. PMID:34318869
Planarian Anatomy Ontology: a resource to connect data within and across experimental platforms. PMID:34318308
EVI1 activates tumor-promoting transcriptional enhancers in pancreatic cancer. PMID:34316710
LncRNA AC007255.1, an immune-related prognostic enhancer RNA in esophageal cancer. PMID:34316393
Analysis of long intergenic non-coding RNAs transcriptomic profiling in skeletal muscle growth during porcine embryonic development. PMID:34315913
Single-cell transcriptome of bronchoalveolar lavage fluid reveals sequential change of macrophages during SARS-CoV-2 infection in ferrets. PMID:34315893
Enhancing the interoperability of glycan data flow between ChEBI, PubChem and GlyGen. PMID:34314492
Study on potential differentially expressed genes in stroke by bioinformatics analysis. PMID:34313877
VarSAn: associating pathways with a set of genomic variants using network analysis. PMID:34313777
Host preference and invasiveness of commensal bacteria in the Lotus and Arabidopsis root microbiota. PMID:34312531
Transcriptome Characterization and Identification of Molecular Markers (SNP, SSR, and Indels) in the Medicinal Plant Sarcandra glabra spp. PMID:34307686
High Expression Levels of CDK1 and CDC20 in Patients With Lung Squamous Cell Carcinoma are Associated With Worse Prognosis. PMID:34307447
Autophagy-Related Genes in Atherosclerosis. PMID:34306596
The Role of INAPERTURATE POLLEN1 as a Pollen Aperture Factor Is Conserved in the Basal Eudicot Eschscholzia californica (Papaveraceae). PMID:34305989
The Wild Sugarcane and Sorghum Kinomes: Insights Into Expansion, Diversification, and Expression Patterns. PMID:34305969
The Compressed Vocabulary of Microbial Life. PMID:34305827
Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia. PMID:34301992
CFTR Lifecycle Map-A Systems Medicine Model of CFTR Maturation to Predict Possible Active Compound Combinations. PMID:34299207
Drugs and Epigenetic Molecular Functions. A Pharmacological Data Scientometric Analysis. PMID:34298869
SPTAN1 Expression Predicts Treatment and Survival Outcomes in Colorectal Cancer. PMID:34298848
ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease. PMID:34298131
Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease. PMID:34297416
Bioinformatics analysis of PAE family in Populus trichocarpa and responsiveness to carbon and nitrogen treatment. PMID:34295610
Context-dependent effects of whole-genome duplication during mammary tumor recurrence. PMID:34294755
Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression. PMID:34294073
Genetic mapping of novel modifiers for ApcMin induced intestinal polyps' development using the genetic architecture power of the collaborative cross mice. PMID:34294033
Highly accurate protein structure prediction for the human proteome. PMID:34293799
Proteome plasticity in response to persistent environmental change. PMID:34293321
Key Candidate Genes - VSIG2 of Colon Cancer Identified by Weighted Gene Co-Expression Network Analysis. PMID:34290531
Identification of Key Genes and Underlying Mechanisms in Acute Kawasaki Disease Based on Bioinformatics Analysis. PMID:34290221
Sequence-based features that are determinant for tail-anchored membrane protein sorting in eukaryotes. PMID:34288289
Transcriptomic Analysis Exploring the Molecular Mechanisms of Hanchuan Zupa Granules in Alleviating Asthma in Rat. PMID:34285702
Full-length transcriptome assembly of andrias davidianus (amphibia: caudata) skin via hybrid sequencing. PMID:34282833
Analyzing the gonadal transcriptome of the frog Hoplobatrachus rugulosus to identify genes involved in sex development. PMID:34281525
Transcriptomic analyses of cacao flavonoids produced in photobioreactors. PMID:34281511
Identification of genes predicting unfavorable prognosis in hepatitis B virus-associated hepatocellular carcinoma. PMID:34277775
Biomarker Categorization in Transcriptomic Meta-Analysis by Concordant Patterns With Application to Pan-Cancer Studies. PMID:34276766
Comparative Label-Free Quantitative Proteomics Analysis Reveals the Essential Roles of N-Glycans in Salt Tolerance by Modulating Protein Abundance in Arabidopsis. PMID:34276718
Analysis of the Taxonomy and Pathogenic Factors of Pectobacterium aroidearum L6 Using Whole-Genome Sequencing and Comparative Genomics. PMID:34276610
Genomic Analysis of Sarcomyxa edulis Reveals the Basis of Its Medicinal Properties and Evolutionary Relationships. PMID:34276589
Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity. PMID:34276573
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools. PMID:34273149
Correlation between targeted RNAseq signature of breast cancer CTCs and onset of bone-only metastases. PMID:34272498
FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure. PMID:34272244
An ancestral recombination graph of human, Neanderthal, and Denisovan genomes. PMID:34272242
Transcriptome analysis of resistant and susceptible mulberry responses to Meloidogyne enterolobii infection. PMID:34271854
MSCFS: inferring circRNA functional similarity based on multiple data sources. PMID:34271851
Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism. PMID:34271221
Oxidation of Hemoglobin Drives a Proatherogenic Polarization of Macrophages in Human Atherosclerosis. PMID:34269613
Gene and protein expression profiles of olfactory ensheathing cells from olfactory bulb versus olfactory mucosa. PMID:34269221
Hippocampus chronic deep brain stimulation induces reversible transcript changes in a macaque model of mesial temporal lobe epilepsy. PMID:34267068
Global analysis of protein lysine 2-hydroxyisobutyrylation (Khib) profiles in Chinese herb rhubarb (Dahuang). PMID:34266380
Polychlorinated biphenyls induce oxidative stress and metabolic responses in astrocytes. PMID:34265337
Multimarker profiling identifies protective and harmful immune processes in heart failure: findings from BIOSTAT-CHF. PMID:34264317
A network-biology approach for identification of key genes and pathways involved in malignant peritoneal mesothelioma. PMID:34261301
A protein interactions map of multiple organ systems associated with COVID-19 disease. PMID:34261299
Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease. PMID:34258055
Genome sequence of Apostasia ramifera provides insights into the adaptive evolution in orchids. PMID:34256691
Accurate transcriptome assembly by Nanopore RNA sequencing reveals novel functional transcripts in hepatocellular carcinoma. PMID:34255396
Computationally scalable regression modeling for ultrahigh-dimensional omics data with ParProx. PMID:34254998
Application across species of a one health approach to liquid sample handling for respiratory based -omics analysis. PMID:34253818
stPlus: a reference-based method for the accurate enhancement of spatial transcriptomics. PMID:34252941
'Single-subject studies'-derived analyses unveil altered biomechanisms between very small cohorts: implications for rare diseases. PMID:34252934
DeepGraphGO: graph neural network for large-scale, multispecies protein function prediction. PMID:34252926
Bioinformatics Analysis Reveals Crosstalk Among Platelets, Immune Cells, and the Glomerulus That May Play an Important Role in the Development of Diabetic Nephropathy. PMID:34249963
Transcriptomic Signature of Human Embryonic Thyroid Reveals Transition From Differentiation to Functional Maturation. PMID:34249923
In silico-driven analysis of the Glossina morsitans morsitans antennae transcriptome in response to repellent or attractant compounds. PMID:34249514
Comparative analysis of fatty acid metabolism based on transcriptome sequencing of wild and cultivated Ophiocordyceps sinensis. PMID:34249512
Overlapping Structures Detection in Protein-Protein Interaction Networks Using Community Detection Algorithm Based on Neighbor Clustering Coefficient. PMID:34249104
Genetic Divergence and Population Structure in Weedy and Cultivated Broomcorn Millets (Panicum miliaceum L.) Revealed by Specific-Locus Amplified Fragment Sequencing (SLAF-Seq). PMID:34249058
Trajectories of Homoeolog-Specific Expression in Allotetraploid Tragopogon castellanus Populations of Independent Origins. PMID:34249049
DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies. PMID:34246298
Transcriptomic and metabolomic profiles of Zea mays fed with urea and ammonium. PMID:34245168
TIDB: a comprehensive database of trained immunity. PMID:34244719
MicroRNA-378a-3p is overexpressed in psoriasis and modulates cell cycle arrest in keratinocytes via targeting BMP2 gene. PMID:34244572
Approximate search for known gene clusters in new genomes using PQ-trees. PMID:34243815
Full-Length Transcriptome Analysis Reveals Candidate Genes Involved in Terpenoid Biosynthesis in Artemisia argyi. PMID:34239538
Exosomes Derived From Heat Stroke Cases Carry miRNAs Associated With Inflammation and Coagulation Cascade. PMID:34239515
Dissecting immune cell stat regulation network reveals biomarkers to predict ICB therapy responders in melanoma. PMID:34238310
Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice. PMID:34237282
Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches. PMID:34237135
Tumor Purity Coexpressed Genes Related to Immune Microenvironment and Clinical Outcomes of Lung Adenocarcinoma. PMID:34234827
Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis. PMID:34233200
In-Cell Labeling and Mass Spectrometry for Systems-Level Structural Biology. PMID:34232610
Identification of endometriosis-associated genes and pathways based on bioinformatic analysis. PMID:34232189
Identification of potential core genes in esophageal carcinoma using bioinformatics analysis. PMID:34232175
Transcriptomic analysis of the black tiger shrimp (Penaeus monodon) reveals insights into immune development in their early life stages. PMID:34230553
A circular RNAs dataset landscape reveals potential signatures for the detection and prognosis of early-stage lung adenocarcinoma. PMID:34229638
Consensus clustering applied to multi-omics disease subtyping. PMID:34229612
Transcriptome analysis of chloride intracellular channel knockdown in Drosophila identifies oxidation-reduction function as possible mechanism of altered sensitivity to ethanol sedation. PMID:34228751
Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors. PMID:34226488
Coordinated changes in gene expression kinetics underlie both mouse and human erythroid maturation. PMID:34225769
Visual comprehension and orientation into the COVID-19 CIDO ontology. PMID:34224898
Identification of differential key biomarkers in the synovial tissue between rheumatoid arthritis and osteoarthritis using bioinformatics analysis. PMID:34224029
ReporterSeq reveals genome-wide dynamic modulators of the heat shock response across diverse stressors. PMID:34223816
A comprehensive review of integrative pharmacology-based investigation: A paradigm shift in traditional Chinese medicine. PMID:34221858
Comprehensive Analysis of Regulatory Network for LINC00472 in Clear Cell Renal Cell Carcinoma. PMID:34221297
Individuality in the Immune Repertoire and Induced Response of the Sponge Halichondria panicea. PMID:34220847
9-Gene Signature Correlated With CD8+ T Cell Infiltration Activated by IFN-γ: A Biomarker of Immune Checkpoint Therapy Response in Melanoma. PMID:34220795
A novel computational drug repurposing approach for Systemic Lupus Erythematosus (SLE) treatment using Semantic Web technologies. PMID:34220244
Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model. PMID:34219376
Open chromatin in grapevine marks candidate CREs and with other chromatin features correlates with gene expression. PMID:34219317
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy. PMID:34215680
Fundamental limits on the rate of bacterial growth and their influence on proteomic composition. PMID:34214468
ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions. PMID:34214142
Linear functional organization of the omic embedding space. PMID:34213534
Control of tissue development and cell diversity by cell cycle-dependent transcriptional filtering. PMID:34212855
IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme. PMID:34211498
Comparative Transcriptome Analysis Reveals Regulatory Networks during the Maize Ear Shank Elongation Process. PMID:34209973
Annotating the Insect Regulatory Genome. PMID:34209769
Conservation of Zebrafish MicroRNA-145 and Its Role during Neural Crest Cell Development. PMID:34209401
Transcriptome Reveals Roles of Lignin-Modifying Enzymes and Abscisic Acid in the Symbiosis of Mycena and Gastrodia elata. PMID:34207287
Genome-Wide Transcriptomic Analysis of Non-Tumorigenic Tissues Reveals Aging-Related Prognostic Markers and Drug Targets in Renal Cell Carcinoma. PMID:34207247
Expression Status and Prognostic Value of m6A RNA Methylation Regulators in Lung Adenocarcinoma. PMID:34206803
Transcriptomic Profiling of Femoral Veins in Deep Vein Thrombosis in a Porcine Model. PMID:34206566
Secretory microRNA Profiles of Third- and Fourth-Stage Dirofilaria immitis Larvae with Different Macrocyclic Lactone Susceptibility: In Search of Biomarkers for Early Detection of Infection. PMID:34206439
Transcriptomic and Metabolic Profiling of High-Temperature Treated Storage Roots Reveals the Mechanism of Saccharification in Sweetpotato (Ipomoea batatas (L.) Lam.). PMID:34206151
A Comprehensive Bioinformatics Analysis of Notch Pathways in Bladder Cancer. PMID:34205690
Evaluation of Indigenous Olive Biocontrol Rhizobacteria as Protectants against Drought and Salt Stress. PMID:34204989
Short Time-Series Expression Transcriptome Data Reveal the Gene Expression Patterns of Dairy Cow Mammary Gland as Milk Yield Decreased Process. PMID:34203058
Relationship of the Pine Growth Promoting Pantoea eucalypti FBS135 with Type Strains P. eucalypti LMG 24197T and P. vagans 24199T. PMID:34202644
Global Proteomic Profiling of Pediatric AML: A Pilot Study. PMID:34202615
Analysing Complex Oral Protein Samples: Complete Workflow and Case Analysis of Salivary Pellicles. PMID:34202147
Predicting Lifestyle from Positive Selection Data and Genome Properties in Oomycetes. PMID:34202069
Differential Expression and Functional Analysis of CircRNA in the Ovaries of Low and High Fecundity Hanper Sheep. PMID:34201517
Differential Glycosite Profiling-A Versatile Method to Compare Membrane Glycoproteomes. PMID:34200965
S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity. PMID:34200797
Differential Transcript Profiles in Cumulus-Oocyte Complexes Originating from Pre-Ovulatory Follicles of Varied Physiological Maturity in Beef Cows. PMID:34200628
Neuronal Cytoskeleton in Intellectual Disability: From Systems Biology and Modeling to Therapeutic Opportunities. PMID:34200511
Genotoxicity and Gene Expression in the Rat Lung Tissue following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO2 NM). PMID:34200147
Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes. PMID:34199492
Nanopore-based full-length transcriptome sequencing of Muscovy duck (Cairina moschata) ovary. PMID:34198095
Intra-heterogeneity in transcription and chemoresistant property of leukemia-initiating cells in murine Setd2-/- acute myeloid leukemia. PMID:34196511
Animals Models of Inherited Retinal Disease. PMID:34196320
A prognostic nomogram based on competing endogenous RNA network for clear-cell renal cell carcinoma. PMID:34196116
Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth. PMID:34195686
Extracellular matrix remodeling associated with bleomycin-induced lung injury supports pericyte-to-myofibroblast transition. PMID:34195593
Enhancing the production of amphotericin B by Strepyomyces nodosus in a 50-ton bioreactor based on comparative genomic analysis. PMID:34194892
Characterization of Human Genes Modulated by Porphyromonas gingivalis Highlights the Ribosome, Hypothalamus, and Cholinergic Neurons. PMID:34194426
Multiple responses contribute to the enhanced drought tolerance of the autotetraploid Ziziphus jujuba Mill. var. spinosa. PMID:34193297
Altered hypothalamic DNA methylation and stress-induced hyperactivity following early life stress. PMID:34193254
Upregulated CD58 is associated with clinicopathological characteristics and poor prognosis of patients with pancreatic ductal adenocarcinoma. PMID:34193136
The subtype-specific molecular function of SPDEF in breast cancer and insights into prognostic significance. PMID:34191390
In-Frame and Frameshift Mutations in Zebrafish Presenilin 2 Affect Different Cellular Functions in Young Adult Brains. PMID:34189411
Identification of genes modulated by interferon gamma in breast cancer cells. PMID:34189281
Epigenetic effects of parasites and pesticides on captive and wild nestling birds. PMID:34188846
The amniotic fluid cell-free transcriptome in spontaneous preterm labor. PMID:34188072
Reconstruction of the full-length transcriptome of cigar tobacco without a reference genome and characterization of anion channel/transporter transcripts. PMID:34187357
Expression levels of specific microRNAs are increased after exercise and are associated with cognitive improvement in Parkinson's disease. PMID:34184078
Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments. PMID:34183813
Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites. PMID:34182772
Potential therapeutic target genes for systemic lupus erythematosus: a bioinformatics analysis. PMID:34180358
ACSNI: An unsupervised machine-learning tool for prediction of tissue-specific pathway components using gene expression profiles. PMID:34179848
Identification ACTA2 and KDR as key proteins for prognosis of PD-1/PD-L1 blockade therapy in melanoma. PMID:34179721
Identification of Dysregulated Complement Activation Pathways Driven by N-Glycosylation Alterations in T2D Patients. PMID:34178943
Low Expression of ADCY4 Predicts Worse Survival of Lung Squamous Cell Carcinoma Based on Integrated Analysis and Immunohistochemical Verification. PMID:34178627
Rapid Body-Wide Transcriptomic Turnover During Rhesus Macaque Perinatal Development. PMID:34177627
Acute Effects on the Human Peripheral Blood Transcriptome of Decompression Sickness Secondary to Scuba Diving. PMID:34177613
Proteomic and Transcriptomic Analyses Provide Novel Insights into the Crucial Roles of Host-Induced Carbohydrate Metabolism Enzymes in Xanthomonas oryzae pv. oryzae Virulence and Rice-Xoo Interaction. PMID:34176023
Single-cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions. PMID:34173975
The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus. PMID:34172766
Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity. PMID:34169837
FINER: enhancing the prediction of tissue-specific functions of isoforms by refining isoform interaction networks. PMID:34169280
Single-Cell RNA-seq Identification of the Cellular Molecular Characteristics of Sporadic Bilateral Clear Cell Renal Cell Carcinoma. PMID:34168986
Bioinformatic Analysis of Hepatocellular Carcinoma Cell Lines to the Efficacy of Nimotuzumab. PMID:34168487
Genome instability-related long non-coding RNA in clear renal cell carcinoma determined using computational biology. PMID:34167490
Survival prediction based on the gene expression associated with cancer morphology and microenvironment in primary central nervous system lymphoma. PMID:34166375
Study of the Active Components and Molecular Mechanism of Tripterygium wilfordii in the Treatment of Diabetic Nephropathy. PMID:34164430
Identification and Validation of a Novel Prognosis Prediction Model in Adrenocortical Carcinoma by Integrative Bioinformatics Analysis, Statistics, and Machine Learning. PMID:34164395
Revealing the Characteristics of the Antarctic Snow Alga Chlorominima collina gen. et sp. nov. Through Taxonomy, Physiology, and Transcriptomics. PMID:34163502
Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemur Megaladapis edwardsi. PMID:34162703
The brain transcriptome of the wolf spider, Schizocosa ocreata. PMID:34162407
Precision omics data integration and analysis with interoperable ontologies and their application for COVID-19 research. PMID:34159360
Dissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA. PMID:34158510
Identification of Somatic Gene Signatures in Circulating Cell-Free DNA Associated with Disease Progression in Metastatic Prostate Cancer by a Novel Machine Learning Platform. PMID:34157173
MetamORF: a repository of unique short open reading frames identified by both experimental and computational approaches for gene and metagene analyses. PMID:34156446
Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence. PMID:34156290
Identification of sex-specific biomarkers predicting new-onset heart failure. PMID:34156155
Disentangling transcriptional responses in plant defense against arthropod herbivores. PMID:34155286
A small RNA regulates pprM, a modulator of pleiotropic proteins promoting DNA repair, in Deinococcus radiodurans under ionizing radiation. PMID:34155239
Cell landscape atlas for patients with chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy constructed using single-cell RNA sequencing. PMID:34153003
Analysis of differentially expressed genes responsible for the suppressive effect of anisomycin on cell proliferation of DLD-1 cells. PMID:34151031
Biological Mechanisms Induced by Soybean Agglutinin Using an Intestinal Cell Model of Monogastric Animals. PMID:34150879
Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells. PMID:34149804
Agrobacterium VirE2 Protein Modulates Plant Gene Expression and Mediates Transformation From Its Location Outside the Nucleus. PMID:34149784
Transcriptome Analysis Reveals Putative Target Genes of APETALA3-3 During Early Floral Development in Nigella damascena L. PMID:34149759
Damage-Net: A program for DNA repair meta-analysis identifies a network of novel repair genes that facilitate cancer evolution. PMID:34147942
Combining QTL-seq and linkage mapping to fine map a candidate gene in qCTS6 for cold tolerance at the seedling stage in rice. PMID:34147069
A chromosome-level genome assembly of rugged rose (Rosa rugosa) provides insights into its evolution, ecology, and floral characteristics. PMID:34145222
RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence. PMID:34142064
Somatic mutation subtypes of lung adenocarcinoma in East Asian reveal divergent biological characteristics and therapeutic vulnerabilities. PMID:34142036
Evolving Up-regulation of Biliary Fibrosis-Related Extracellular Matrix Molecules After Successful Portoenterostomy. PMID:34141988
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases. PMID:34140509
Mapping the multiscale structure of biological systems. PMID:34139169
Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. PMID:34137816
Association of medically assisted reproduction with offspring cord blood DNA methylation across cohorts. PMID:34136910
Pan-Genome Analysis of Vibrio cholerae and Vibrio metschnikovii Strains Isolated From Migratory Birds at Dali Nouer Lake in Chifeng, China. PMID:34136552
Transcriptome Profiling Analysis of the Testis After Eyestalk Ablation for Selection of the Candidate Genes Involved in the Male Sexual Development in Macrobrachium nipponense. PMID:34135943
Transcriptomic Signature Differences Between SARS-CoV-2 and Influenza Virus Infected Patients. PMID:34135895
Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence. PMID:34135888
An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family. PMID:34134783
Transcriptomics of type 2 diabetic and healthy human neutrophils. PMID:34134627
Transcriptomic coordination at hepatic steatosis indicates robust immune cell engagement prior to inflammation. PMID:34134614
RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells. PMID:34134472
Protopanaxadiol improves endometriosis associated infertility and miscarriage in sex hormones receptors-dependent and independent manners. PMID:34131393
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas. PMID:34131149
Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner. PMID:34130712
Identifying Genomic Regions Targeted During Eggplant Domestication Using Transcriptome Data. PMID:34130314
Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs. PMID:34128958
A methyl esterase 1 (PvMES1) promotes the salicylic acid pathway and enhances Fusarium wilt resistance in common beans. PMID:34128089
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells. PMID:34127967
Interaction Between the Intestinal Microbial Community and Transcriptome Profile in Common Carp (Cyprinus carpio L.). PMID:34127924
Inter-individual body mass variations relate to fractionated functional brain hierarchies. PMID:34127795
A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study. PMID:34126933
Multiple Lesions Contribute to Infertility in Males Lacking Autoimmune Regulator. PMID:34126085
DGLinker: flexible knowledge-graph prediction of disease-gene associations. PMID:34125897
Droplet microarrays for cell culture: effect of surface properties and nanoliter culture volume on global transcriptomic landscape. PMID:34124640
Identification of CD8+ T Cell-Related Genes: Correlations with Immune Phenotypes and Outcomes of Liver Cancer. PMID:34124275
Highly connected, non-redundant microRNA functional control in breast cancer molecular subtypes. PMID:34123357
FGGA-lnc: automatic gene ontology annotation of lncRNA sequences based on secondary structures. PMID:34123354
Gene Instability-Related lncRNA Prognostic Model of Melanoma Patients via Machine Learning Strategy. PMID:34122546
Identification of Key Biomarkers and Immune Infiltration in Sciatic Nerve of Diabetic Neuropathy BKS-db/db Mice by Bioinformatics Analysis. PMID:34122109
Network Pharmacology-Based Validation of the Efficacy of Huiyangjiuji Decoction in the Treatment of Experimental Colitis. PMID:34122086
Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain. PMID:34121661
DNA methylation profile of liver of mice conceived by in vitro fertilization. PMID:34121654
The aging mouse lens transcriptome. PMID:34119483
miR-1224 contributes to ischemic stroke-mediated natural killer cell dysfunction by targeting Sp1 signaling. PMID:34118948
De novo genome assembly of a foxtail millet cultivar Huagu11 uncovered the genetic difference to the cultivar Yugu1, and the genetic mechanism of imazethapyr tolerance. PMID:34118890
Revealing the Modular Similarities and Differences Among Alzheimer's Disease, Vascular Dementia, and Parkinson's Disease in Genomic Networks. PMID:34117614
Mortalin/glucose-regulated protein 75 promotes the cisplatin-resistance of gastric cancer via regulating anti-oxidation/apoptosis and metabolic reprogramming. PMID:34117210
CCDC114, DNAI2 and TOP2A involves in the effects of tibolone treatment on postmenopausal endometrium. PMID:34116668
Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias. PMID:34113825
Measuring pathway database coverage of the phosphoproteome. PMID:34113485
Characterization of the small RNA transcriptomes of cell protrusions and cell bodies of highly metastatic hepatocellular carcinoma cells via RNA sequencing. PMID:34113396
A report of two cases of bulbospinal form Alexander disease and preliminary exploration of the disease. PMID:34109421
Heat-killed endophytic bacterium induces robust plant defense responses against important pathogens. PMID:34108579
Gene expression changes and DNA damage after ex vivo exposure of peripheral blood cells to various CT photon spectra. PMID:34103547
Integrating longitudinal clinical laboratory tests with targeted proteomic and transcriptomic analyses reveal the landscape of host responses in COVID-19. PMID:34103487
Characterization of nucleic acids from extracellular vesicle-enriched human sweat. PMID:34103018
Protein functional module identification method combining topological features and gene expression data. PMID:34103008
Analysis of single-cell RNA sequencing data based on autoencoders. PMID:34103004
TNF blockade uncouples toxicity from antitumor efficacy induced with CD40 chemoimmunotherapy. PMID:34101617
Molecular omics resources should require sex annotation: a call for action. PMID:34099934
Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength. PMID:34099702
Comprehensive Phosphoproteomic Analysis of Nostoc flagelliforme in Response to Dehydration Provides Insights into Plant ROS Signaling Transduction. PMID:34095650
Transcriptome Analysis Reveals Differentially Expressed Genes and Long Non-coding RNAs Associated With Fecundity in Sheep Hypothalamus With Different FecB Genotypes. PMID:34095109
Gene Cascade Shift and Pathway Enrichment in Rat Kidney Induced by Acarbose Through Comparative Analysis. PMID:34095098
Sharp Downregulation of Hub Genes Associated With the Pathogenesis of Breast Cancer From Ductal Carcinoma In Situ to Invasive Ductal Carcinoma. PMID:34094915
Laryngeal squamous cell carcinoma cell lines show high tolerance for siRNA-mediated CDK1 knockdown. PMID:34094670
Cancer cell-selective modulation of mitochondrial respiration and metabolism by potent organogold(iii) dithiocarbamates. PMID:34094305
Comparing Statistical Tests for Differential Network Analysis of Gene Modules. PMID:34093641
Integrative Analysis of lncRNA and mRNA and Profiles in Postoperative Delirium Patients. PMID:34093168
Differential expression of striatal proteins in a mouse model of DOPA-responsive dystonia reveals shared mechanisms among dystonic disorders. PMID:34092491
The REASON score: an epigenetic and clinicopathologic score to predict risk of poor survival in patients with early stage oral squamous cell carcinoma. PMID:34090518
The effect of methanol fixation on single-cell RNA sequencing data. PMID:34090348
Beach sand oil spills select for generalist microbial populations. PMID:34088976
Chamber-enriched gene expression profiles in failing human hearts with reduced ejection fraction. PMID:34088950
PIGNON: a protein-protein interaction-guided functional enrichment analysis for quantitative proteomics. PMID:34088263
Mapping Proximity Associations of Core Spindle Assembly Checkpoint Proteins. PMID:34087075
Transmembrane adaptor protein PAG is a mediator of PD-1 inhibitory signaling in human T cells. PMID:34083754
A combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in Escherichia coli. PMID:34083440
Patterns of recent natural selection on genetic loci associated with sexually differentiated human body size and shape phenotypes. PMID:34081690
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns. PMID:34080738
Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre. PMID:34078907
Identification of biomarkers, pathways and potential therapeutic target for docetaxel resistant prostate cancer. PMID:34077304
Chromosome-level genome assembly of the Chinese longsnout catfish Leiocassis longirostris. PMID:34075735
Learning from Embryogenesis-A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development. PMID:34073664
Proteomic Analyses of Vitreous in Proliferative Diabetic Retinopathy: Prior Studies and Future Outlook. PMID:34070658
Regulation of Oxalate Metabolism in Spinach Revealed by RNA-Seq-Based Transcriptomic Analysis. PMID:34069886
Identification of Critical Genes and Signaling Pathways in Human Monocytes Following High-Intensity Exercise. PMID:34067297
Integrating Transcriptome and Coexpression Network Analyses to Characterize Salicylic Acid- and Jasmonic Acid-Related Genes in Tolerant Poplars Infected with Rust. PMID:34066822
Microarray and qPCR Analysis of Mitochondrial Metabolism Activation during Prenatal and Early Postnatal Development in Rats and Humans with Emphasis on CoQ10 Biosynthesis. PMID:34066731
Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat Diets with Different Linoleic Acid (LA, C18:2n-6) to α-Linolenic Acid (ALA, C18:3n-3) Ratio on the Mouse Liver Proteome. PMID:34063343
Skeletal Muscle Gene Expression Profile in Response to Caloric Restriction and Aging: A Role for SirT1. PMID:34063079
Host Response of Atlantic Salmon (Salmo salar) Re-Inoculated with Paramoeba perurans. PMID:34062978
Identification of Potential Bisphenol A (BPA) Exposure Biomarkers in Ovarian Cancer. PMID:34062972
An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability. PMID:34061819
The liver-clock coordinates rhythmicity of peripheral tissues in response to feeding. PMID:34059820
Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype. PMID:34059749
The chromosome-level Stevia genome provides insights into steviol glycoside biosynthesis. PMID:34059662
Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis. PMID:34059062
The transcriptional repressor Rev-erbα regulates circadian expression of the astrocyte Fabp7 mRNA. PMID:34056625
Synthesis, Characterization, and Specific Localization of Mitochondrial-Targeted Antioxidant Peptide SS31 Probe. PMID:34056004
Comprehensive analysis of the long non-coding RNA expression profile and functional roles in a contrast-induced acute kidney injury rat model. PMID:34055056
Multi-Omics Approach in the Identification of Potential Therapeutic Biomolecule for COVID-19. PMID:34054532
Multi-Dimensional Transcriptome Analysis Reveals Modulation of Cholesterol Metabolism as Highly Integrated Response to Brain Injury. PMID:34054419
Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics. PMID:34052751
Rapid evolution of mammalian APLP1 as a synaptic adhesion molecule. PMID:34050225
snpXplorer: a web application to explore human SNP-associations and annotate SNP-sets. PMID:34048563
Integrated Gene Co-expression Analysis and Metabolites Profiling Highlight the Important Role of ZmHIR3 in Maize Resistance to Gibberella Stalk Rot. PMID:34046051
Pneumolysin Is Responsible for Differential Gene Expression and Modifications in the Epigenetic Landscape of Primary Monocyte Derived Macrophages. PMID:34046027
Glycoproteomic analysis of the changes in protein N-glycosylation during neuronal differentiation in human-induced pluripotent stem cells and derived neuronal cells. PMID:34045517
Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation. PMID:34045476
Inferring Genome-Wide Correlations of Mutation Fitness Effects between Populations. PMID:34043790
Transcriptional signatures of human peripheral blood mononuclear cells can identify the risk of tuberculosis progression from latent infection among individuals with silicosis. PMID:34042560
Linking Lysosomal Enzyme Targeting Genes and Energy Metabolism with Altered Gray Matter Volume in Children with Persistent Stuttering. PMID:34041495
In Arabidopsis thaliana Cd differentially impacts on hormone genetic pathways in the methylation defective ddc mutant compared to wild type. PMID:34040101
Structure-based protein function prediction using graph convolutional networks. PMID:34039967
Context-Dependent miR-21 Regulation of TLR7-Mediated Autoimmune and Foreign Antigen-Driven Antibody-Forming Cell and Germinal Center Responses. PMID:34039637
Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR. PMID:34039602
Common pathways and functional profiles reveal underlying patterns in Breast, Kidney and Lung cancers. PMID:34039407
Identification of significant genes as prognostic markers and potential tumor suppressors in lung adenocarcinoma via bioinformatical analysis. PMID:34039311
NetGO 2.0: improving large-scale protein function prediction with massive sequence, text, domain, family and network information. PMID:34038555
G2PDeep: a web-based deep-learning framework for quantitative phenotype prediction and discovery of genomic markers. PMID:34037802
CPA: a web-based platform for consensus pathway analysis and interactive visualization. PMID:34037798
ARHGDIA Confers Selective Advantage to Dissociated Human Pluripotent Stem Cells. PMID:34036793
AMOTL2‑knockdown promotes the proliferation, migration and invasion of glioma by regulating β‑catenin nuclear localization. PMID:34036399
Differential gene expression profile by RNA sequencing study of elderly osteoporotic hip fracture patients with sarcopenia. PMID:34036042
PhenCards: a data resource linking human phenotype information to biomedical knowledge. PMID:34034817
Gene Ontology Meta Annotator for Plants (GOMAP). PMID:34034755
De novo transcriptome sequencing and anthocyanin metabolite analysis reveals leaf color of Acer pseudosieboldianum in autumn. PMID:34034673
GWENA: gene co-expression networks analysis and extended modules characterization in a single Bioconductor package. PMID:34034647
Coordination of microbe-host homeostasis by crosstalk with plant innate immunity. PMID:34031541
Estimates of gene ensemble noise highlight critical pathways and predict disease severity in H1N1, COVID-19 and mortality in sepsis patients. PMID:34031464
Transcriptomic response of brain tissue to focused ultrasound-mediated blood-brain barrier disruption depends strongly on anesthesia. PMID:34027087
Genome sequence and transcriptome profiles of pathogenic fungus Paecilomyces penicillatus reveal its interactions with edible fungus Morchella importuna. PMID:34025947
TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma. PMID:34025646
DNF: A differential network flow method to identify rewiring drivers for gene regulatory networks. PMID:34025035
Valproic Acid Protects Against Acute Kidney Injury in Hemorrhage and Trauma. PMID:34023578
Gene expression of intracortical bone demonstrates loading-induced increases in Wnt1 and Ngf and inhibition of bone remodeling processes. PMID:34023542
Up-regulated RFC2 predicts unfavorable progression in hepatocellular carcinoma. PMID:34022962
Transcriptome analysis reveals potential function of long non-coding RNAs in 20-hydroxyecdysone regulated autophagy in Bombyx mori. PMID:34022797
Chromosome-scale assembly of the Sparassis latifolia genome obtained using long-read and Hi-C sequencing. PMID:34021320
Chromatin-associated MRN complex protects highly transcribing genes from genomic instability. PMID:34020942
Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. PMID:34020725
DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web. PMID:34019664
Rcl1 depletion impairs 18S pre-rRNA processing at the A1-site and up-regulates a cohort of ribosome biogenesis genes in zebrafish. PMID:34019640
Defining the role of the polyasparagine repeat domain of the S. cerevisiae transcription factor Azf1p. PMID:34019539
Hub biomarkers for the diagnosis and treatment of glioblastoma based on microarray technology. PMID:34018447
A method for benchmarking genetic screens reveals a predominant mitochondrial bias. PMID:34018332
Deciphering the architecture and interactome of hnRNP proteins and enigmRBPs. PMID:34017973
Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving β-Cell Maturation. PMID:34017831
Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education. PMID:34014253
Genome variation in colorectal cancer patient with liver metastasis measured by whole-exome sequencing. PMID:34012644
Cholesterol-Induced M4-Like Macrophages Recruit Neutrophils and Induce NETosis. PMID:34012454
Identification of the EMT-Related Genes Signature for Predicting Occurrence and Progression in Thyroid Cancer. PMID:34012269
Chromosomal instability by mutations in the novel minor spliceosome component CENATAC. PMID:34009673
Activated mast cells in skeletal muscle can be a potential mediator for cancer-associated cachexia. PMID:34008339
A novel diagnostic signature based on three circulating exosomal mircoRNAs for chronic obstructive pulmonary disease. PMID:34007326
Analyzing host-viral interactome of SARS-CoV-2 for identifying vulnerable host proteins during COVID-19 pathogenesis. PMID:34004362
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. PMID:34002087
Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis. PMID:34002013
A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells. PMID:34001972
The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac. PMID:34001900
Primordial super-enhancers: heat shock-induced chromatin organization in yeast. PMID:34001402
Learning adaptive representations for entity recognition in the biomedical domain. PMID:34001263
SynLeGG: analysis and visualization of multiomics data for discovery of cancer 'Achilles Heels' and gene function relationships. PMID:33997893
Evaluating the Consistency of Gene Methylation in Liver Cancer Using Bisulfite Sequencing Data. PMID:33996828
Simultaneous profiling of Arabidopsis thaliana and Vibrio vulnificus MO6-24/O transcriptomes by dual RNA-seq analysis. PMID:33995904
Cycad-Weevil Pollination Symbiosis Is Characterized by Rapidly Evolving and Highly Specific Plant-Insect Chemical Communication. PMID:33995438
Mutant PRPF8 Causes Widespread Splicing Changes in Spliceosome Components in Retinitis Pigmentosa Patient iPSC-Derived RPE Cells. PMID:33994920
Multimodality assessment of heart failure with preserved ejection fraction skeletal muscle reveals differences in the machinery of energy fuel metabolism. PMID:33991175
Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions. PMID:33988505
Mechanistic insight into the progressive retinal atrophy disease in dogs via pathway-based genome-wide association analysis. PMID:33987558
Properties and gene expression profiling of acquired radioresistance in mouse breast cancer cells. PMID:33987326
Centromere protein N may be a novel malignant prognostic biomarker for hepatocellular carcinoma. PMID:33987018
Identification of a five-gene signature in association with overall survival for hepatocellular carcinoma. PMID:33986994
ARTEMIS: A Novel Mass-Spec Platform for HLA-Restricted Self and Disease-Associated Peptide Discovery. PMID:33986749
Hypericum perforatum L. Regulates Glutathione Redox Stress and Normalizes Ggt1/Anpep Signaling to Alleviate OVX-Induced Kidney Dysfunction. PMID:33981220
Network-based identification of key master regulators associated with an immune-silent cancer phenotype. PMID:33979427
A termination-independent role of Rat1 in cotranscriptional splicing. PMID:33978753
Identification of a novel autophagy signature for predicting survival in patients with lung adenocarcinoma. PMID:33976960
Integrated analysis of three newly sequenced fern chloroplast genomes: Genome structure and comparative analysis. PMID:33976830
Haplotype-resolved genome assembly enables gene discovery in the red palm weevil Rhynchophorus ferrugineus. PMID:33976235
Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance. PMID:33976213
Overcoming false-positive gene-category enrichment in the analysis of spatially resolved transcriptomic brain atlas data. PMID:33976144
hu.MAP 2.0: integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies. PMID:33973408
Comparative transcriptomics between Drosophila mojavensis and D. arizonae reveals transgressive gene expression and underexpression of spermatogenesis-related genes in hybrid testes. PMID:33972659
Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data. PMID:33972534
Simultaneous learning of individual microRNA-gene interactions and regulatory comodules. PMID:33971820
Comparative Analysis of piRNA Profiles Helps to Elucidate Cryoinjury Between Giant Panda and Boar Sperm During Cryopreservation. PMID:33969033
Network Pharmacology-Based Prediction of Mechanism of Shenzhuo Formula for Application to DKD. PMID:33968154
Single-Cell Transcriptomics: Current Methods and Challenges in Data Acquisition and Analysis. PMID:33967674
Reactome and the Gene Ontology: Digital convergence of data resources. PMID:33964129
Collagen fiber regulation in human pediatric aortic valve development and disease. PMID:33963260
Intestinal mucosa-derived DNA methylation signatures in the penetrating intestinal mucosal lesions of Crohn's disease. PMID:33963246
Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals. PMID:33963185
Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells. PMID:33961804
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. PMID:33961781
Retinoic acid induces NELFA-mediated 2C-like state of mouse embryonic stem cells associates with epigenetic modifications and metabolic processes in chemically defined media. PMID:33960560
Updates to HCOP: the HGNC comparison of orthology predictions tool. PMID:33959747
Common genetic associations between age-related diseases. PMID:33959723
The Links of Ghrelin to Incretins, Insulin, Glucagon, and Leptin After Bariatric Surgery. PMID:33959145
Comparison and Functional Analysis of Chemosensory Protein Genes From Eucryptorrhynchus scrobiculatus Motschulsky and Eucryptorrhynchus brandti Harold. PMID:33959040
Cell-Type-Specific Gene Modules Related to the Regional Homogeneity of Spontaneous Brain Activity and Their Associations With Common Brain Disorders. PMID:33958982
The genome of a wild Medicago species provides insights into the tolerant mechanisms of legume forage to environmental stress. PMID:33957908
Screening and identification of LMNB1 and DLGAP5, two key biomarkers in gliomas. PMID:33956061
Evidence for phloem loading via the abaxial bundle sheath cells in maize leaves. PMID:33955497
Transcriptional signatures of synaptic vesicle genes define myotonic dystrophy type I neurodegeneration. PMID:33955002
Knowledge-Based Biomedical Data Science. PMID:33954284
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways. PMID:33954053
Molecular evidence of the avocado defense response to Fusarium kuroshium infection: a deep transcriptome analysis using RNA-Seq. PMID:33954045
Use of Network Pharmacology to Explore the Mechanism of Gegen (Puerariae lobatae Radix) in the Treatment of Type 2 Diabetes Mellitus Associated with Hyperlipidemia. PMID:33953784
Identification and Analysis of Aux/IAA Family in Acer rubrum. PMID:33953533
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity. PMID:33953401
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease. PMID:33953184
Transcriptomic meta-analysis of disuse muscle atrophy vs. resistance exercise-induced hypertrophy in young and older humans. PMID:33951310
Complete chloroplast genome sequencing of Job's tears (Coix L.): genome structure, comparative analysis, and phylogenetic relationships. PMID:33948493
The genomic basis of evolutionary differentiation among honey bees. PMID:33947700
Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain. PMID:33947435
Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures. PMID:33946875
Integrative Systems Biology Approaches to Identify Potential Biomarkers and Pathways of Cervical Cancer. PMID:33946372
An evolutionary genomic approach reveals both conserved and species-specific genetic elements related to human disease in closely related Aspergillus fungi. PMID:33944921
Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3. PMID:33944776
Protein structure-based gene expression signatures. PMID:33941686
Functional and genetic determinants of mutation rate variability in regulatory elements of cancer genomes. PMID:33941236
Strategies for detecting and identifying biological signals amidst the variation commonly found in RNA sequencing data. PMID:33941086
RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7. PMID:33937236
Predicting Tumor Cell Response to Synergistic Drug Combinations Using a Novel Simplified Deep Learning Model. PMID:33936513
Genome-Wide Gene Expression Analysis of Mtb-Infected DC Highlights the Rapamycin-Driven Modulation of Regulatory Cytokines via the mTOR/GSK-3β Axis. PMID:33936070
De-novo Assembly of Limnospira fusiformis Using Ultra-Long Reads. PMID:33936015
Transcriptomic and microRNA Expression Profiles Identify Biomarkers for Predicting Neo-Chemoradiotherapy Response in Esophageal Squamous Cell Carcinomas (ESCC). PMID:33935718
Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan-Dou-Fu-Mu Decoction for Treatment of Wilson Disease Using a Toxic Milk Mouse Model. PMID:33935715
Basic leucine zipper (bZIP) transcription factor genes and their responses to drought stress in ginseng, Panax ginseng C.A. Meyer. PMID:33932982
Whole-genome resequencing of Osmanthus fragrans provides insights into flower color evolution. PMID:33931610
GAPGOM-an R package for gene annotation prediction using GO Metrics. PMID:33931103
Comparative transcriptomic analysis reveals the regulatory mechanism of the gibberellic acid pathway of Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn.) dwarf mutants. PMID:33931042
Transcriptome-Wide Gene Expression in a Murine Model of Ventilator-Induced Lung Injury. PMID:33927789
Genome-wide gene expression changes of Pseudomonas veronii 1YdBTEX2 during bioaugmentation in polluted soils. PMID:33926576
Best practices on the differential expression analysis of multi-species RNA-seq. PMID:33926528
Categorization of Orthologous Gene Clusters in 92 Ascomycota Genomes Reveals Functions Important for Phytopathogenicity. PMID:33925458
Assessing Various Control Samples for Microarray Gene Expression Profiling of Laryngeal Squamous Cell Carcinoma. PMID:33923685
Transcriptomic Analysis of Pseudomonas aeruginosa Response to Pine Honey via RNA Sequencing Indicates Multiple Mechanisms of Antibacterial Activity. PMID:33923242
Characterization of the Survival Influential Genes in Carcinogenesis. PMID:33922264
Connectivity Map Analysis of a Single-Cell RNA-Sequencing -Derived Transcriptional Signature of mTOR Signaling. PMID:33922083
Performance Comparison of Deep Learning Autoencoders for Cancer Subtype Detection Using Multi-Omics Data. PMID:33921978
A First Insight into the Gonad Transcriptome of Hong Kong Catfish (Clarias fuscus). PMID:33920938
Mapping of Genetic Locus for Leaf Trichome Formation in Chinese Cabbage Based on Bulked Segregant Analysis. PMID:33919922
Isolation and Characterization of Strain Exiguobacterium sp. KRL4, a Producer of Bioactive Secondary Metabolites from a Tibetan Glacier. PMID:33919419
Discovery of Post-Translational Modifications in Emiliania huxleyi. PMID:33918234
Investigation of the Initial Host Response of Naïve Atlantic Salmon (Salmo salar) Inoculated with Paramoeba perurans. PMID:33918228
Altered microRNA Transcriptome in Cultured Human Liver Cells upon Infection with Ebola Virus. PMID:33917562
Genome-Wide Mapping of Histone H3 Lysine 4 Trimethylation (H3K4me3) and Its Involvement in Fatty Acid Biosynthesis in Sunflower Developing Seeds. PMID:33917507
Genome and Pangenome Analysis of Lactobacillus hilgardii FLUB-A New Strain Isolated from Mead. PMID:33917427
Systematic Analysis of the Transcriptome Profiles and Co-Expression Networks of Tumour Endothelial Cells Identifies Several Tumour-Associated Modules and Potential Therapeutic Targets in Hepatocellular Carcinoma. PMID:33917186
Sphingosine Promotes Embryo Biomass in Upland Cotton: A Biochemical and Transcriptomic Analysis. PMID:33915924
Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis. PMID:33914608
Purification and quantitative proteomic analysis of cell bodies and protrusions. PMID:33912849
Single-Cell Atlas Reveals Fatty Acid Metabolites Regulate the Functional Heterogeneity of Mesenchymal Stem Cells. PMID:33912565
Identification of Expression Patterns and Potential Prognostic Significance of m5C-Related Regulators in Head and Neck Squamous Cell Carcinoma. PMID:33912441
Reproductive Proteins Evolve Faster Than Non-reproductive Proteins Among Solanum Species. PMID:33912206
In silico annotation of unreviewed acetylcholinesterase (AChE) in some lepidopteran insect pest species reveals the causes of insecticide resistance. PMID:33911936
The prognostic value of an autophagy-related lncRNA signature in hepatocellular carcinoma. PMID:33910497
5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer's disease. PMID:33910000
Boosting Detection of Low-Abundance Proteins in Thermal Proteome Profiling Experiments by Addition of an Isobaric Trigger Channel to TMT Multiplexes. PMID:33908254
Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator. PMID:33904398
Extracellular Vesicles from Human Adipose-Derived Mesenchymal Stem Cells: A Review of Common Cargos. PMID:33904115
Semantic standards of external exposome data. PMID:33901445
Identification of Metastasis-Associated MicroRNAs in Metastatic Melanoma by miRNA Expression Profile and Experimental Validation. PMID:33897771
Comprehensive RNA-Seq Profiling Reveals Temporal and Tissue-Specific Changes in Gene Expression in Sprague-Dawley Rats as Response to Heat Stress Challenges. PMID:33897767
The VRNetzer platform enables interactive network analysis in Virtual Reality. PMID:33893283
Transcriptomic analysis of α-linolenic acid content and biosynthesis in Paeonia ostii fruits and seeds. PMID:33892636
Transcriptome analysis reveals gene responses to herbicide, tribenuron methyl, in Brassica napus L. during seed germination. PMID:33892633
Chromosome-level genome assembly of the hard-shelled mussel Mytilus coruscus, a widely distributed species from the temperate areas of East Asia. PMID:33891010
Differential Expression of Insulin-Like Growth Factor 1 and Wnt Family Member 4 Correlates With Functional Heterogeneity of Human Dermal Fibroblasts. PMID:33889572
Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability. PMID:33889300
System-Level Analysis of Alzheimer's Disease Prioritizes Candidate Genes for Neurodegeneration. PMID:33889174
The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation. PMID:33888695
An atlas of the tissue and blood metagenome in cancer reveals novel links between bacteria, viruses and cancer. PMID:33888160
Isolation and genomic characterization of five novel strains of Erysipelotrichaceae from commercial pigs. PMID:33888068
Expression Profiles Reveal Involvement of VEGF, IGF1, BIRC5, and MMP1 in Vulvar Carcinogenesis. PMID:33888009
Resilience, plasticity and robustness in gene expression during aging in the brain of outbred deer mice. PMID:33882817
27-Hydroxycholesterol is a specific factor in the neoplastic microenvironment of HCC that causes MDR via GRP75 regulation of the redox balance and metabolic reprogramming. PMID:33880675
Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin. PMID:33880588
Brain proteomic changes by histone deacetylase inhibition after traumatic brain injury. PMID:33880414
Identification of key genes and pathways in discoid lupus skin via bioinformatics analysis. PMID:33879674
An ensemble of the iCluster method to analyze longitudinal lncRNA expression data for psoriasis patients. PMID:33879268
An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies. PMID:33875015
Identification of the specific long-noncoding RNAs involved in night-break mediated flowering retardation in Chenopodium quinoa. PMID:33874907
Expression and prognosis analyses of BUB1, BUB1B and BUB3 in human sarcoma. PMID:33872216
Gut Microbiome Changes with Acute Diarrheal Disease in Urban Versus Rural Settings in Northern Ecuador. PMID:33872206
Predictive Models of Genetic Redundancy in Arabidopsis thaliana. PMID:33871641
Ontology-Based Graphs of Research Communities: A Tool for Understanding Threat Reduction Networks. PMID:33870041
An Extracellular Matrix-Based Signature Associated With Immune Microenvironment Predicts the Prognosis and Therapeutic Responses of Patients With Oesophageal Squamous Cell Carcinoma. PMID:33869274
CCR7 Has Potential to Be a Prognosis Marker for Cervical Squamous Cell Carcinoma and an Index for Tumor Microenvironment Change. PMID:33869272
Subtypes identification on heart failure with preserved ejection fraction via network enhancement fusion using multi-omics data. PMID:33868594
Is acupuncture effective in the treatment of COVID-19 related symptoms? Based on bioinformatics/network topology strategy. PMID:33866350
DUSP7 regulates the activity of ERK2 to promote proper chromosome alignment during cell division. PMID:33865857
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. PMID:33864768
The mechanism of TiaoGanYiPi formula for treating chronic hepatitis B by network pharmacology and molecular docking verification. PMID:33863948
Conserved long-range base pairings are associated with pre-mRNA processing of human genes. PMID:33863890
Bioinformatic analysis identifies potential biomarkers and therapeutic targets of septic-shock-associated acute kidney injury. PMID:33863396
IrGO: Iranian traditional medicine General Ontology and knowledge base. PMID:33863373
Silencing SHMT2 inhibits the progression of tongue squamous cell carcinoma through cell cycle regulation. PMID:33863325
Identification and Validation of a Tumor Microenvironment-Related Gene Signature for Prognostic Prediction in Advanced-Stage Non-Small-Cell Lung Cancer. PMID:33860055
Utilizing network pharmacology and molecular docking to explore the underlying mechanism of Guizhi Fuling Wan in treating endometriosis. PMID:33859874
Disparate Interferon Signaling and Shared Aberrant Basaloid Cells in Single-Cell Profiling of Idiopathic Pulmonary Fibrosis and Systemic Sclerosis-Associated Interstitial Lung Disease. PMID:33859634
PCprophet: a framework for protein complex prediction and differential analysis using proteomic data. PMID:33859439
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes. PMID:33859415
Multi-omic profiling of pituitary thyrotropic cells and progenitors. PMID:33858413
Interacting impact of maternal inflammatory response and stress on the amygdala transcriptome of pigs. PMID:33856433
Unraveling Heterogeneity of Tumor Cells and Microenvironment and Its Clinical Implications for Triple Negative Breast Cancer. PMID:33854958
Integrated Genomic and Transcriptomic Analysis reveals key genes for predicting dual-phenotype Hepatocellular Carcinoma Prognosis. PMID:33854600
CD8+ T Lymphocyte Coexpression Genes Correlate with Immune Microenvironment and Overall Survival in Breast Cancer. PMID:33854546
Proteomic characterization of the human lens and Cataractogenesis. PMID:33849365
Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences. PMID:33849068
Lipoprotein DolP supports proper folding of BamA in the bacterial outer membrane promoting fitness upon envelope stress. PMID:33847565
Nanopore long-read RNA-seq and absolute quantification delineate transcription dynamics in early embryo development of an insect pest. PMID:33846393
Microbial community characterization of shrimp survivors to AHPND challenge test treated with an effective shrimp probiotic (Vibrio diabolicus). PMID:33845910
Improved characterisation of clinical text through ontology-based vocabulary expansion. PMID:33845909
Bioinformatics analysis of the expression and role of microRNA-221-3p in head and neck squamous cell carcinoma. PMID:33845800
The transcriptomic responses of Atlantic salmon (Salmo salar) to high temperature stress alone, and in combination with moderate hypoxia. PMID:33845767
Functional annotation of lung cancer‒associated genetic variants by cell type‒specific epigenome and long-range chromatin interactome. PMID:33840167
Editor's introduction to this issue (G&I 19:1, 2021). PMID:33840165
Machine learning revealed stemness features and a novel stemness-based classification with appealing implications in discriminating the prognosis, immunotherapy and temozolomide responses of 906 glioblastoma patients. PMID:33839757
Identification of transcriptomic signatures and crucial pathways involved in non-alcoholic steatohepatitis. PMID:33837926
Dual-process brain mitochondria isolation preserves function and clarifies protein composition. PMID:33836587
Large-Scale Phenomic and Genomic Analysis of Brain Asymmetrical Skew. PMID:33836062
Tumor Microenvironment Proteomics: Lessons From Multiple Myeloma. PMID:33833982
Molecular mechanisms detected in yak lung tissue via transcriptome-wide analysis provide insights into adaptation to high altitudes. PMID:33833362
Prediction of Streptococcus uberis clinical mastitis treatment success in dairy herds by means of mass spectrometry and machine-learning. PMID:33833319
lncRNA C2dat2 facilitates autophagy and apoptosis via the miR-30d-5p/DDIT4/mTOR axis in cerebral ischemia-reperfusion injury. PMID:33833132
Common low complexity regions for SARS-CoV-2 and human proteomes as potential multidirectional risk factor in vaccine development. PMID:33832440
MicroCellClust: mining rare and highly specific subpopulations from single-cell expression data. PMID:33830183
High BLM Expression Predicts Poor Clinical Outcome and Contributes to Malignant Progression in Human Cholangiocarcinoma. PMID:33828983
M2 Macrophage Co-Expression Factors Correlate With Immune Phenotype and Predict Prognosis of Bladder Cancer. PMID:33828973
Prognostic Implication of the Expression Level of PECAM-1 in Non-small Cell Lung Cancer. PMID:33828969
Transcriptomic Analysis of Mouse Brain After Traumatic Brain Injury Reveals That the Angiotensin Receptor Blocker Candesartan Acts Through Novel Pathways. PMID:33828448
The chromosome-level Hemerocallis citrina Borani genome provides new insights into the rutin biosynthesis and the lack of colchicine. PMID:33828071
Integrated genomic analysis reveals key features of long undecoded transcript isoform-based gene repression. PMID:33826921
Establishing a consensus for the hallmarks of cancer based on gene ontology and pathway annotations. PMID:33823788
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer. PMID:33822745
miRSM: an R package to infer and analyse miRNA sponge modules in heterogeneous data. PMID:33822666
Gene expression evaluation of antioxidant enzymes in patients with hepatocellular carcinoma: RT-qPCR and bioinformatic analyses. PMID:33821873
Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets. PMID:33821260
The construction and analysis of a ferroptosis-related gene prognostic signature for pancreatic cancer. PMID:33819918
Application and evaluation of knowledge graph embeddings in biomedical data. PMID:33816992
CogNet: classification of gene expression data based on ranked active-subnetwork-oriented KEGG pathway enrichment analysis. PMID:33816987
Immunogenomic Profiling Demonstrate AC003092.1 as an Immune-Related eRNA in Glioblastoma Multiforme. PMID:33815468
Identification of Novel Sensitive and Reliable Serovar-Specific Targets for PCR Detection of Salmonella Serovars Hadar and Albany by Pan-Genome Analysis. PMID:33815306
Weighted Gene Coexpression Network Analysis Reveals Essential Genes and Pathways in Bipolar Disorder. PMID:33815158
Comparative Analysis of Adelphocoris suturalis Jakovlev (Hemiptera: Miridae) Immune Responses to Fungal and Bacterial Pathogens. PMID:33815150
Proteomic reveals the influences of smoke-water and karrikinolide on the biosynthesis of salvianolic acids and lignins in Salvia miltiorrhiza hairy roots. PMID:33811528
Strategies to Modulate Specialized Metabolism in Mediterranean Crops: From Molecular Aspects to Field. PMID:33809189
Single-Molecule Long-Read Sequencing of Purslane (Portulaca oleracea) and Differential Gene Expression Related with Biosynthesis of Unsaturated Fatty Acids. PMID:33808162
Metabolome and Transcriptome Analyses Reveal the Regulatory Mechanisms of Photosynthesis in Developing Ginkgo biloba Leaves. PMID:33807564
Distinct miRNA Signatures and Networks Discern Fetal from Adult Erythroid Differentiation and Primary from Immortalized Erythroid Cells. PMID:33807258
CircRNA-Protein Interactions in Muscle Development and Diseases. PMID:33806945
Identification of Genomic Regions Associated with Concentrations of Milk Fat, Protein, Urea and Efficiency of Crude Protein Utilization in Grazing Dairy Cows. PMID:33806889
Transcriptomic Diversity in the Livers of South African Sardines Participating in the Annual Sardine Run. PMID:33806647
Mutations of Intrinsically Disordered Protein Regions Can Drive Cancer but Lack Therapeutic Strategies. PMID:33806614
Functional Annotation of a Full-Length Transcriptome and Identification of Genes Associated with Flower Development in Rhododendronsimsii (Ericaceae). PMID:33805478
Withholding of M-CSF Supplement Reprograms Macrophages to M2-Like via Endogenous CSF-1 Activation. PMID:33805444
Selective Activation of CNS and Reference PPARGC1A Promoters Is Associated with Distinct Gene Programs Relevant for Neurodegenerative Diseases. PMID:33804860
Innate Resistance and Phosphite Treatment Affect Both the Pathogen's and Host's Transcriptomes in the Tanoak-Phytophthora ramorum Pathosystem. PMID:33803362
A Comparison of the Transcriptomes of Cowpeas in Response to Two Different Ionizing Radiations. PMID:33802840
Rice Transcriptome Analysis Reveals Nitrogen Starvation Modulates Differential Alternative Splicing and Transcript Usage in Various Metabolism-Related Genes. PMID:33801769
Candidate Genes for the High-Altitude Adaptations of Two Mountain Pine Taxa. PMID:33801727
Transcriptome Analysis Reveals Genes Involved in Thermogenesis in Two Cold-Exposed Sheep Breeds. PMID:33800742
Regulation of Juvenile Hormone on Summer Diapause of Geleruca daurica and Its Pathway Analysis. PMID:33799822
Volume-constrained microcontainers enable myoepithelial functional differentiation in highly parallel mammary organoid culture. PMID:33796842
HARVESTMAN: a framework for hierarchical feature learning and selection from whole genome sequencing data. PMID:33794760
Anno genominis XX: 20 years of Arabidopsis genomics. PMID:33793861
Building blocks and blueprints for bacterial autolysins. PMID:33793553
Validation of intraosseous delivery of valproic acid in a swine model of polytrauma. PMID:33791436
Weighted Gene Coexpression Network Analysis Uncovers Critical Genes and Pathways for Multiple Brain Regions in Parkinson's Disease. PMID:33791366
Construction of a Prognostic Gene Signature Associated with Immune Infiltration in Glioma: A Comprehensive Analysis Based on the CGGA. PMID:33790966
Identification of Candidate Genes Conferring Cold Tolerance to Rice (Oryza sativa L.) at the Bud-Bursting Stage Using Bulk Segregant Analysis Sequencing and Linkage Mapping. PMID:33790929
Trans-acting genetic variation affects the expression of adjacent genes. PMID:33789351
Wormicloud: a new text summarization tool based on word clouds to explore the C. elegans literature. PMID:33787871
An expanding manifold in transmodal regions characterizes adolescent reconfiguration of structural connectome organization. PMID:33787489
FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia. PMID:33786575
A Wnt-mediated phenotype switch along the epithelial-mesenchymal axis defines resistance and invasion downstream of ionising radiation in oral squamous cell carcinoma. PMID:33785878
Integration of multi-omics approaches for functional characterization of muscle related selective sweep genes in Nanchukmacdon. PMID:33785872
Deciphering the transcriptomic regulation of heat stress responses in Nothofagus pumilio. PMID:33784314
Clotting in COVID-19: Is It All in the Genes? PMID:33784208
Dysregulation of circRNA expression in the peripheral blood of individuals with schizophrenia and bipolar disorder. PMID:33782720
Modular genome-wide gene expression architecture shared by early traits of osteoporosis and atherosclerosis in the Young Finns Study. PMID:33782480
Screening of osteoarthritis diagnostic markers based on immune-related genes and immune infiltration. PMID:33782454
Perspective: targeting VEGF-A and YKL-40 in glioblastoma - matter matters. PMID:33779510
IL-8, MSPa, MIF, FGF-9, ANG-2 and AgRP collection were identified for the diagnosis of colorectal cancer based on the support vector machine model. PMID:33779485
Characterization of a Deep Sea Bacillus toyonensis Isolate: Genomic and Pathogenic Features. PMID:33777842
Transcriptome Analysis of Ovarian Follicles Reveals Potential Pivotal Genes Associated With Increased and Decreased Rates of Chicken Egg Production. PMID:33777097
Regulatory Function of Sympathetic Innervation on the Endo/Lysosomal Trafficking of Acetylcholine Receptor. PMID:33776791
CTD Anatomy: analyzing chemical-induced phenotypes and exposures from an anatomical perspective, with implications for environmental health studies. PMID:33768211
The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development. PMID:33767158
Hepatic steatosis and steatohepatitis: a functional meta-analysis of sex-based differences in transcriptomic studies. PMID:33766130
The first complete mitochondrial genome of eggplant (Solanum melongena). PMID:33763537
A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of Hypoxia. PMID:33763387
Identification of a Metabolism-Related Signature for the Prediction of Survival in Endometrial Cancer Patients. PMID:33763366
Genomic Loci Affecting Milk Production in German Black Pied Cattle (DSN). PMID:33763120
Comparative transcriptome and metabolome analysis of Ostrinia furnacalis female adults under UV-A exposure. PMID:33762675
Genome-wide association analysis reveals regulation of at-risk loci by DNA methylation in prostate cancer. PMID:33762478
The identification of neutrophils-mediated mechanisms and potential therapeutic targets for the management of sepsis-induced acute immunosuppression using bioinformatics. PMID:33761636
Piggybacking on Niche Adaptation Improves the Maintenance of Multidrug-Resistance Plasmids. PMID:33760032
SBGN Bricks Ontology as a tool to describe recurring concepts in molecular networks. PMID:33758926
G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease. PMID:33758195
Overexpression of CCNE1 confers a poorer prognosis in triple-negative breast cancer identified by bioinformatic analysis. PMID:33757543
Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia. PMID:33756103
PTENε suppresses tumor metastasis through regulation of filopodia formation. PMID:33755220
TALE: Transformer-based protein function Annotation with joint sequence-Label Embedding. PMID:33755048
Identification of pivotal genes associated with the prognosis of gastric carcinoma through integrated analysis. PMID:33754626
Genome-wide identification of MIKC-type genes related to stamen and gynoecium development in Liriodendron. PMID:33753780
The evolution of ancestral and species-specific adaptations in snowfinches at the Qinghai-Tibet Plateau. PMID:33753478
Critical role of the BAF chromatin remodeling complex during murine neural crest development. PMID:33750945
The identification of circular RNAs from peripheral blood mononuclear cells in systemic lupus erythematosus. PMID:33750387
Integrated microRNA and transcriptome profiling reveal key miRNA-mRNA interaction pairs associated with seed development in Tartary buckwheat (Fagopyrum tataricum). PMID:33750309
Noise regularization removes correlation artifacts in single-cell RNA-seq data preprocessing. PMID:33748795
Coexpressed Genes That Promote the Infiltration of M2 Macrophages in Melanoma Can Evaluate the Prognosis and Immunotherapy Outcome. PMID:33748290
Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation. PMID:33747980
Comprehensive In Silico Analysis of a Novel Serum Exosome-Derived Competitive Endogenous RNA Network for Constructing a Prognostic Model for Glioblastoma. PMID:33747903
Pairwise Versus Multiple Global Network Alignment. PMID:33747670
Identification of Pivotal MicroRNAs and Target Genes Associated with Persistent Atrial Fibrillation Based on Bioinformatics Analysis. PMID:33747117
Transcriptome and Comparative Chloroplast Genome Analysis of Vincetoxicum versicolor: Insights Into Molecular Evolution and Phylogenetic Implication. PMID:33747039
The Molecular Basis of Kale Domestication: Transcriptional Profiling of Developing Leaves Provides New Insights Into the Evolution of a Brassica oleracea Vegetative Morphotype. PMID:33747016
Identification of molecular biomarkers and pathways of NSCLC: insights from a systems biomedicine perspective. PMID:33742334
Identification of disease treatment mechanisms through the multiscale interactome. PMID:33741907
Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instability. PMID:33741065
Differential microRNAs expression profiles in liver from three different lifestyle modification mice models. PMID:33740891
High expression of COL5A2, a member of COL5 family, indicates the poor survival and facilitates cell migration in gastric cancer. PMID:33739392
Applications of Machine Learning in Human Microbiome Studies: A Review on Feature Selection, Biomarker Identification, Disease Prediction and Treatment. PMID:33737920
Prediction of LncRNA-encoded small peptides in glioma and oligomer channel functional analysis using in silico approaches. PMID:33735310
Natural variation in the regulation of neurodevelopmental genes modifies flight performance in Drosophila. PMID:33735180
Aberrant proteins expressed in skin fibroblasts of Parkinson's disease patients carrying heterozygous variants of glucocerebrosidase and parkin genes. PMID:33732455
Screening and verification of hub genes involved in osteoarthritis using bioinformatics. PMID:33732303
Ultrafast functional profiling of RNA-seq data for nonmodel organisms. PMID:33731361
Chronic villitis of unknown etiology: Investigations into viral pathogenesis. PMID:33730616
A KDM5-Prospero transcriptional axis functions during early neurodevelopment to regulate mushroom body formation. PMID:33729157
Integration of summary data from GWAS and eQTL studies identified novel risk genes for coronary artery disease. PMID:33725943
A perfusable, multifunctional epicardial device improves cardiac function and tissue repair. PMID:33723455
How to Get Started with Single Cell RNA Sequencing Data Analysis. PMID:33722930
Transcriptome Expression of Biomineralization Genes in Littoraria flava Gastropod in Brazilian Rocky Shore Reveals Evidence of Local Adaptation. PMID:33720344
Identification of genes that correlate clear cell renal cell carcinoma and obesity and exhibit potential prognostic value. PMID:33718070
Identification of the hub genes in gastric cancer through weighted gene co-expression network analysis. PMID:33717664
Comprehensive Quantitative Proteome Analysis of Aedes aegypti Identifies Proteins and Pathways Involved in Wolbachia pipientis and Zika Virus Interference Phenomenon. PMID:33716790
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. PMID:33713620
The Counteracting Effects of Demography on Functional Genomic Variation: The Roma Paradigm. PMID:33713133
Genome-wide transcriptome profiling uncovers differential miRNAs and lncRNAs in ovaries of Hu sheep at different developmental stages. PMID:33712687
Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products. PMID:33712660
Identification of four key prognostic genes and three potential drugs in human papillomavirus negative head and neck squamous cell carcinoma. PMID:33712015
Identification of potential and novel target genes in pituitary prolactinoma by bioinformatics analysis. PMID:33709028
Coronary artery disease: differential expression of ceRNAs and interaction analyses. PMID:33708856
Transcriptome Analysis of the Inhibitory Effect of Sennoside A on the Metastasis of Hepatocellular Carcinoma Cells. PMID:33708105
Joint analysis of expression levels and histological images identifies genes associated with tissue morphology. PMID:33707455
Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy. PMID:33693820
UbiNet 2.0: a verified, classified, annotated and updated database of E3 ubiquitin ligase-substrate interactions. PMID:33693667
Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models. PMID:33693642
Copper Availability Influences the Transcriptomic Response of Candida albicans to Fluconazole Stress. PMID:33693623
Data Analytics Applications for Streaming Data From Social Media: What to Predict? PMID:33693318
Four potential microRNAs affect the progression of pancreatic ductal adenocarcinoma by targeting MET via the PI3K/AKT signaling pathway. PMID:33692858
Macrophage M2 Co-expression Factors Correlate With the Immune Microenvironment and Predict Outcome of Renal Clear Cell Carcinoma. PMID:33692827
Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts. PMID:33692466
Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color. PMID:33692100
Changes in protein expression due to metformin treatment and hyperinsulinemia in a human endometrial cancer cell line. PMID:33690729
Biodegradation of lignin monomers and bioconversion of ferulic acid to vanillic acid by Paraburkholderia aromaticivorans AR20-38 isolated from Alpine forest soil. PMID:33687503
Long non-coding RNAs ENST00000429730.1 and MSTRG.93125.4 are associated with metabolic activity in tuberculosis lesions of sputum-negative tuberculosis patients. PMID:33686954
Identification and validation of three core genes in p53 signaling pathway in hepatitis B virus-related hepatocellular carcinoma. PMID:33685467
Identification of permissive amber suppression sites for efficient non-canonical amino acid incorporation in mammalian cells. PMID:33684219
The very early evolution of protein translocation across membranes. PMID:33684113
DeepViral: prediction of novel virus-host interactions from protein sequences and infectious disease phenotypes. PMID:33682875
Identification of Tumor Tissue of Origin with RNA-Seq Data and Using Gradient Boosting Strategy. PMID:33681364
Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis. PMID:33679879
Comprehensive circRNA Expression Profile and Construction of circRNAs-Related ceRNA Network in a Mouse Model of Autism. PMID:33679870
Analysing the yeast complexome-the Complex Portal rising to the challenge. PMID:33677561
MACMIC Reveals A Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes. PMID:33677108
Giant ankyrin-G regulates cardiac function. PMID:33675749
Comparative analysis of chloroplast genomes of kenaf cytoplasmic male sterile line and its maintainer line. PMID:33674697
Comparison of plasma and cerebrospinal fluid proteomes identifies gene products guiding adult neurogenesis and neural differentiation in birds. PMID:33674647
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages. PMID:33674584
Unique Human and Mouse β-Cell Senescence-Associated Secretory Phenotype (SASP) Reveal Conserved Signaling Pathways and Heterogeneous Factors. PMID:33674410
AP-1 subunits converge promiscuously at enhancers to potentiate transcription. PMID:33674350
ETS-Domain Transcription Factor Elk-1 Regulates Stemness Genes in Brain Tumors and CD133+ BrainTumor-Initiating Cells. PMID:33672811
Integrative Analysis Identified Key Schizophrenia Risk Factors from an Abnormal Behavior Mouse Gene Set. PMID:33672431
Germline and Somatic Whole-Exome Sequencing Identifies New Candidate Genes Involved in Familial Predisposition to Serrated Polyposis Syndrome. PMID:33672345
Comprehensive Proteomics Analysis of In Vitro Canine Oviductal Cell-Derived Extracellular Vesicles. PMID:33672125
Accumulation of the Auxin Precursor Indole-3-Acetamide Curtails Growth through the Repression of Ribosome-Biogenesis and Development-Related Transcriptional Networks. PMID:33670805
Genomic Comparison of Lactobacillus casei AP and Lactobacillus plantarum DR131 with Emphasis on the Butyric Acid Biosynthetic Pathways. PMID:33669502
Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression. PMID:33669337
Identify potential miRNA-mRNA regulatory networks contributing to high-risk neuroblastoma. PMID:33666785
Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants. PMID:33666172
Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance. PMID:33664652
The relationship among Girdin DNA methylation, its high expression, and immune infiltration in hepatocellular carcinoma: Clues from in silico analysis. PMID:33660763
Inheritance of Solanum chloroplast genomic DNA in interspecific hybrids. PMID:33659675
HoSeIn: A Workflow for Integrating Various Homology Search Results from Metagenomic and Metatranscriptomic Sequence Datasets. PMID:33659350
The Changes of Leukocytes in Brain and Blood After Intracerebral Hemorrhage. PMID:33659003
Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A. PMID:33658830
Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis. PMID:33657400
Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia. PMID:33656268
MMP7 as a potential biomarker of colon cancer and its prognostic value by bioinformatics analysis. PMID:33655961
OXPHOS deficiency activates global adaptation pathways to maintain mitochondrial membrane potential. PMID:33655635
Downregulation of miR‑146a inhibits osteoporosis in the jaws of ovariectomized rats by regulating the Wnt/β‑catenin signaling pathway. PMID:33655338
Exploring existing drugs: proposing potential compounds in the treatment of COVID-19. PMID:33655082
A Protocol to Map the Spatial Proteome Using HyperLOPIT in Saccharomyces cerevisiae. PMID:33654815
A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development. PMID:33653874
Cross-species data integration to prioritize causal genes in lipid metabolism. PMID:33651746
Human Chorionic Gonadotropin Modulates the Transcriptome of the Myometrium and Cervix in Late Gestation. PMID:33650091
Complete Genome Sequence Analysis of Brevibacillus laterosporus Bl-zj Reflects its Potential Algicidal Response. PMID:33649996
Peptidomics analysis revealed that a novel peptide VMP‑19 protects against Ang II‑induced injury in human umbilical vein endothelial cells. PMID:33649860
Complete genome sequencing of Bacillus sp. TK-2, analysis of its cold evolution adaptability. PMID:33649356
Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells. PMID:33649334
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions. PMID:33649193
Construction of the optimization prognostic model based on differentially expressed immune genes of lung adenocarcinoma. PMID:33648465
Transcriptome and metabolome profiling provide insights into molecular mechanism of pseudostem elongation in banana. PMID:33648452
Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity. PMID:33647456
Comprehensive analysis of cancer breakpoints reveals signatures of genetic and epigenetic contribution to cancer genome rearrangements. PMID:33647036
RAMP2-AS1 Regulates Endothelial Homeostasis and Aging. PMID:33644072
Identification of mortality-risk-related missense variant for renal clear cell carcinoma using deep learning. PMID:33643601
Whole-Genome Diversification Analysis of the Hornbeam Species Reveals Speciation and Adaptation Among Closely Related Species. PMID:33643339
Potential Molecular Mechanism of TNF Superfamily-Related Genes in Glioblastoma Multiforme Based on Transcriptome and Epigenome. PMID:33643183
PIWI-interacting RNA sequencing profiles in maternal plasma-derived exosomes reveal novel non-invasive prenatal biomarkers for the early diagnosis of nonsyndromic cleft lip and palate. PMID:33639402
Identification of an N-acetylneuraminic acid-presenting bacteria isolated from a human microbiome. PMID:33637779
Retroviral integrations contribute to elevated host cancer rates during germline invasion. PMID:33637755
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer. PMID:33637530
Transcriptome analysis of the role of autophagy in plant response to heat stress. PMID:33635879
A novel DNA methylation-based model that effectively predicts prognosis in hepatocellular carcinoma. PMID:33634306
Knockdown of RIPK2 Inhibits Proliferation and Migration, and Induces Apoptosis via the NF-κB Signaling Pathway in Gastric Cancer. PMID:33633788
Genomic insight into diet adaptation in the biological control agent Cryptolaemus montrouzieri. PMID:33632122
PFP-WGAN: Protein function prediction by discovering Gene Ontology term correlations with generative adversarial networks. PMID:33630862
Genomic Expression Profiling and Bioinformatics Analysis of Chronic Recurrent Multifocal Osteomyelitis. PMID:33628812
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics. PMID:33627808
Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers. PMID:33627787
Discovering microbe-disease associations from the literature using a hierarchical long short-term memory network and an ensemble parser model. PMID:33627732
Conserved Epigenetic Programming and Enhanced Heme Metabolism Drive Memory B Cell Reactivation. PMID:33627377
Genome-wide ancestry and introgression in a Zambian baboon hybrid zone. PMID:33624366
Comprehensive Analysis of Gene Expression Changes and Validation in Hepatocellular Carcinoma. PMID:33623390
Ontology-guided segmentation and object identification for developmental mouse lung immunofluorescent images. PMID:33622235
Seascape genomics reveals candidate molecular targets of heat stress adaptation in three coral species. PMID:33619812
Discovery of molecular features underlying the morphological landscape by integrating spatial transcriptomic data with deep features of tissue images. PMID:33619564
Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation. PMID:33618608
RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila. PMID:33617535
Identification of miRNAs as diagnostic and prognostic markers in hepatocellular carcinoma. PMID:33617479
A New Family of Bacteriolytic Proteins in Dictyostelium discoideum. PMID:33614529
Identification of Primary and Metastatic Lung Cancer-Related lncRNAs and Potential Targeted Drugs Based on ceRNA Network. PMID:33614509
How value-sensitive design can empower sustainable consumption. PMID:33614080
20S proteasomes secreted by the malaria parasite promote its growth. PMID:33608523
Novel signaling pathways regulate SARS-CoV and SARS-CoV-2 infectious disease. PMID:33607766
redPATH: Reconstructing the Pseudo Development Time of Cell Lineages in Single-cell RNA-seq Data and Applications in Cancer. PMID:33607293
Local adaptation contributes to gene expression divergence in maize. PMID:33604670
Public data sources to support systems toxicology applications. PMID:33604492
Transcriptomic Signatures and Functional Network Analysis of Chronic Rhinosinusitis With Nasal Polyps. PMID:33603773
Enrichment analyses of diseases and pathways associated with precocious puberty using PrecocityDB. PMID:33602974
The immune-related biomarker TEK inhibits the development of clear cell renal cell carcinoma (ccRCC) by regulating AKT phosphorylation. PMID:33602230
Quantitative proteomic analysis of pear (Pyrus pyrifolia cv. "Hosui") flesh provides novel insights about development and quality characteristics of fruit. PMID:33599839
Curation of over 10 000 transcriptomic studies to enable data reuse. PMID:33599246
Systems biology analysis identifies TNFRSF9 as a functional marker of tumor-infiltrating regulatory T-cell enabling clinical outcome prediction in lung cancer. PMID:33598101
Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections. PMID:33596852
The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction. PMID:33596422
Ferroptosis-related gene signature as a prognostic marker for lower-grade gliomas. PMID:33594759
Genetic characteristics of Bursaphelenchus xylophilus third-stage dispersal juveniles. PMID:33594100
The KbvR Regulator Contributes to Capsule Production, Outer Membrane Protein Biosynthesis, Antiphagocytosis, and Virulence in Klebsiella pneumoniae. PMID:33593891
Role of opiorphin genes in prostate cancer growth and progression. PMID:33593085
Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection. PMID:33592092
Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells. PMID:33589679
Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response. PMID:33589590
Transcriptome analysis reveals major transcriptional changes during regrowth after mowing of red clover (Trifolium pratense). PMID:33588756
SARS-CoV-2 Proteins Exploit Host's Genetic and Epigenetic Mediators for the Annexation of Key Host Signaling Pathways. PMID:33585554
Identification of Protein Subcellular Localization With Network and Functional Embeddings. PMID:33584818
Identification of Key Modules and Hub Genes of Annulus Fibrosus in Intervertebral Disc Degeneration. PMID:33584795
The CLAIRE COVID-19 initiative: approach, experiences and recommendations. PMID:33584129
Guidelines for biomarker discovery in endometrium: correcting for menstrual cycle bias reveals new genes associated with uterine disorders. PMID:33576824
NetQuilt: Deep Multispecies Network-based Protein Function Prediction using Homology-informed Network Similarity. PMID:33576802
Integration of single-cell datasets reveals novel transcriptomic signatures of β-cells in human type 2 diabetes. PMID:33575641
An empirical bayesian approach for testing gene expression fold change and its application in detecting global dosage effects. PMID:33575620
Functional networks of co-expressed genes to explore iron homeostasis processes in the pathogenic yeast Candida glabrata. PMID:33575583
GSAn: an alternative to enrichment analysis for annotating gene sets. PMID:33575577
Family-specific analysis of variant pathogenicity prediction tools. PMID:33575576
Global variability analysis of mRNA and protein concentrations across and within human tissues. PMID:33575562
Potential Drug Prediction of Glioblastoma Based on Drug Perturbation-Induced Gene Expression Signatures. PMID:33575336
Screening and identification of hub genes in bladder cancer by bioinformatics analysis and KIF11 is a potential prognostic biomarker. PMID:33574944
Gene expression and epigenetics reveal species-specific mechanisms acting upon common molecular pathways in the evolution of task division in bees. PMID:33574391
Sinbase 2.0: An Updated Database to Study Multi-Omics in Sesamum indicum. PMID:33573226
MicroRNA Profiling of HL-1 Cardiac Cells-Derived Extracellular Vesicles. PMID:33573156
Correlation between cortical gene expression and resting-state functional network centrality in healthy young adults. PMID:33570215
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. PMID:33568819
Systematic auditing is essential to debiasing machine learning in biology. PMID:33568741
Comparative transcriptomic analysis revealed novel potential therapeutic targets of traditional Chinese medicine (Pinggan-Qianyang decoction) on vascular remodeling in spontaneously hypertensive rats. PMID:33568194
Ranking cancer drivers via betweenness-based outlier detection and random walks. PMID:33568049
Whole-genome comparative analysis of Malaysian Burkholderia pseudomallei clinical isolates. PMID:33565959
A Molecular network approach reveals shared cellular and molecular signatures between chronic fatigue syndrome and other fatiguing illnesses. PMID:33564792
Microarray Data Mining and Preliminary Bioinformatics Analysis of Hepatitis D Virus-Associated Hepatocellular Carcinoma. PMID:33564675
Integrated bioinformatic analysis identifies COL4A3, COL4A4, and KCNJ1 as key biomarkers in Wilms tumor. PMID:33564352
Classification of node-positive melanomas into prognostic subgroups using keratin, immune, and melanogenesis expression patterns. PMID:33564068
Sulfur Metabolites Play Key System-Level Roles in Modulating Denitrification. PMID:33563788
Modular Reorganization of Signaling Networks during the Development of Colon Adenoma and Carcinoma. PMID:33562960
Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945. PMID:33562780
The microRNA let-7b-5p Is Negatively Associated with Inflammation and Disease Severity in Multiple Sclerosis. PMID:33562569
Genome analysis of Plectus murrayi, a nematode from continental Antarctica. PMID:33561244
Activity of bacteria isolated from bats against Pseudogymnoascus destructans in China. PMID:33559264
Identification of differentially expressed genes involved in amino acid and lipid accumulation of winter turnip rape (Brassica rapa L.) in response to cold stress. PMID:33556109
Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila. PMID:33555999
Integrative Identification of Hub Genes Associated With Immune Cells in Atrial Fibrillation Using Weighted Gene Correlation Network Analysis. PMID:33553270
Transcriptome Based System Biology Exploration Reveals Homogeneous Tumorigenicity of Alimentary Tract Malignancy. PMID:33552958
The functional analysis of ABCG transporters in the adaptation of pigeon pea (Cajanus cajan) to abiotic stresses. PMID:33552725
Circulating plasma exosomal miRNA profiles serve as potential metastasis-related biomarkers for hepatocellular carcinoma. PMID:33552286
MUC4 is a novel mediator in H. pylori infection-related pancreatic cancer. PMID:33552244
Prior Biological Knowledge Improves Genomic Prediction of Growth-Related Traits in Arabidopsis thaliana. PMID:33552126
Host Transcriptomic Response Following Administration of Rotavirus Vaccine in Infants' Mimics Wild Type Infection. PMID:33552046
Integrative Analyses of Genes Associated With Osteoporosis in CD16+ Monocyte. PMID:33551990
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis. PMID:33551818
A Novel 10-Gene Signature Predicts Poor Prognosis in Low Grade Glioma. PMID:33550903
Inhibitory effect of sodium butyrate on colorectal cancer cells and construction of the related molecular network. PMID:33549042
Investigating the relevance of major signaling pathways in cancer survival using a biologically meaningful deep learning model. PMID:33546587
GMO Genetic Elements Thesaurus (GMO-GET): a controlled vocabulary for the consensus designation of introduced or modified genetic elements in genetically modified organisms. PMID:33546585
Prediction and analysis of hub genes between glioblastoma and low-grade glioma using bioinformatics analysis. PMID:33545929
Protuberances are organized distinct regions of long-term callus: histological and transcriptomic analyses in kiwifruit. PMID:33544186
In-silico definition of the Drosophila melanogaster matrisome. PMID:33543012
Genome Assembly and Analyses of the Macrofungus Macrocybe gigantea. PMID:33542921
Development of a prognostic signature for esophageal cancer based on nine immune related genes. PMID:33541291
The Genetics of Sudden Infant Death Syndrome-Towards a Gene Reference Resource. PMID:33540853
BSGatlas: a unified Bacillus subtilis genome and transcriptome annotation atlas with enhanced information access. PMID:33539279
Long non‑coding RNA LINC00491 promotes proliferation and inhibits apoptosis in esophageal squamous cell carcinoma. PMID:33537830
Genome annotation of disease-causing microorganisms. PMID:33537706
Regulatory genomic circuitry of human disease loci by integrative epigenomics. PMID:33536621
IgA transcytosis and antigen recognition govern ovarian cancer immunity. PMID:33536615
Analyses of transcriptomes and the first complete genome of Leucocalocybe mongolica provide new insights into phylogenetic relationships and conservation. PMID:33536487
Novel prognostic genes and subclasses of acute myeloid leukemia revealed by survival analysis of gene expression data. PMID:33536020
GEOlimma: differential expression analysis and feature selection using pre-existing microarray data. PMID:33535967
Identification of microRNA-16-5p and microRNA-21-5p in feces as potential noninvasive biomarkers for inflammatory bowel disease. PMID:33535181
A comprehensive evaluation of skin aging-related circular RNA expression profiles. PMID:33534927
ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways. PMID:33534793
A High-Throughput Method for Identifying Novel Genes That Influence Metabolic Pathways Reveals New Iron and Heme Regulation in Pseudomonas aeruginosa. PMID:33531406
An edge-based statistical analysis of long non-coding RNA expression profiles reveals a negative association between Parkinson's disease and colon cancer. PMID:33531021
Integrative analysis of chloroplast DNA methylation in a marine alga-Saccharina japonica. PMID:33528753
Identifying daily changes in circRNAs and circRNA-associated-ceRNA networks in the rat pineal gland. PMID:33526984
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysis. PMID:33526974
Functional Signatures in Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis of Sex-Based Differences in Transcriptomic Studies. PMID:33526761
Human keratinocyte-derived extracellular vesicles activate the MAPKinase pathway and promote cell migration and proliferation in vitro. PMID:33526070
Systematic Analysis of Functionally Related Gene Clusters in the Opportunistic Pathogen, Candida albicans. PMID:33525750
A Transcriptomic Approach Provides Insights on the Mycorrhizal Symbiosis of the Mediterranean Orchid Limodorum abortivum in Nature. PMID:33525474
Long-Term Waterlogging as Factor Contributing to Hypoxia Stress Tolerance Enhancement in Cucumber: Comparative Transcriptome Analysis of Waterlogging Sensitive and Tolerant Accessions. PMID:33525400
Decreased p53 is associated with a decline in asymmetric stem cell self-renewal in aged human epidermis. PMID:33524216
DeCompress: tissue compartment deconvolution of targeted mRNA expression panels using compressed sensing. PMID:33524140
Introduction to radiomics and radiogenomics in neuro-oncology: implications and challenges. PMID:33521636
Gene Expression Profiling Reveals the Shared and Distinct Transcriptional Signatures in Human Lung Epithelial Cells Infected With SARS-CoV-2, MERS-CoV, or SARS-CoV: Potential Implications in Cardiovascular Complications of COVID-19. PMID:33521069
American lobster postlarvae alter gene regulation in response to ocean warming and acidification. PMID:33520168
The Characteristics of Chemosensory and Opsin Genes in Newly Emerged and Sexually Mature Agrilus planipennis, an Important Quarantine Forest Beetle. PMID:33519910
Identifying RBM47, HCK, CD53, TYROBP, and HAVCR2 as Hub Genes in Advanced Atherosclerotic Plaques by Network-Based Analysis and Validation. PMID:33519905
Genome-Wide Association Study of Maize Aboveground Dry Matter Accumulation at Seedling Stage. PMID:33519889
Insights into triterpene synthesis and unsaturated fatty-acid accumulation provided by chromosomal-level genome analysis of Akebia trifoliata subsp. australis. PMID:33518712
Study on mechanism of matrine in treatment of COVID-19 combined with liver injury by network pharmacology and molecular docking technology. PMID:33517789
Computational resources for identifying and describing proteins driving liquid-liquid phase separation. PMID:33517364
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders. PMID:33515275
Amynthas corticis genome reveals molecular mechanisms behind global distribution. PMID:33514865
The role of gene to gene interaction in the breast's genomic signature of pregnancy. PMID:33514799
Data-driven biological network alignment that uses topological, sequence, and functional information. PMID:33514304
Causal network inference from gene transcriptional time-series response to glucocorticoids. PMID:33513136
Transcriptome annotation in the cloud: complexity, best practices, and cost. PMID:33511996
High-throughput screening in postimplantation haploid epiblast stem cells reveals Hs3st3b1 as a modulator for reprogramming. PMID:33511777
Comprehensive Analysis of ceRNA Regulation Network Involved in the Development of Coronary Artery Disease. PMID:33511207
Elucidation of the Genomic-Epigenomic Interaction Landscape of Aggressive Prostate Cancer. PMID:33511206
Reporting on the Role of miRNAs and Affected Pathways on the Molecular Backbone of Ovarian Insufficiency: A Systematic Review and Critical Analysis Mapping of Future Research. PMID:33511114
Biocontrol Using Bacillus amyloliquefaciens PP19 Against Litchi Downy Blight Caused by Peronophythora litchii. PMID:33510732
Gene signature of children with severe respiratory syncytial virus infection. PMID:33510411
Meta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumors. PMID:33510359
The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy. PMID:33509017
SinEx DB 2.0 update 2020: database for eukaryotic single-exon coding sequences. PMID:33507271
biotoolsSchema: a formalized schema for bioinformatics software description. PMID:33506265
Transcriptome data for tissue-specific genes in four reproductive organs at three developmental stages of micro-tom tomato. PMID:33506081
Identified GNGT1 and NMU as Combined Diagnosis Biomarker of Non-Small-Cell Lung Cancer Utilizing Bioinformatics and Logistic Regression. PMID:33505535
Genome-Wide Identification and Analysis of Chitinase GH18 Gene Family in Mycogone perniciosa. PMID:33505368
Inflammation and regulatory T cell genes are differentially expressed in peripheral blood mononuclear cells of Parkinson's disease patients. PMID:33504893
Integrative analysis of transcriptomic data for identification of T-cell activation-related mRNA signatures indicative of preterm birth. PMID:33504832
DM3Loc: multi-label mRNA subcellular localization prediction and analysis based on multi-head self-attention mechanism. PMID:33503258
Screening and identification of potential biomarkers and therapeutic drugs in melanoma via integrated bioinformatics analysis. PMID:33501609
In Silico Inference of Synthetic Cytotoxic Interactions from Paclitaxel Responses. PMID:33499282
Genome Sequence and Adaptation Analysis of the Human and Rice Pathogenic Strain Burkholderia glumae AU6208. PMID:33498266
Comparative transcriptomics and host-specific parasite gene expression profiles inform on drivers of proliferative kidney disease. PMID:33495500
Cross-platform genomic identification and clinical validation of breast cancer diagnostic biomarkers. PMID:33493140
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice. PMID:33491741
Pearl Sac Gene Expression Profiles Associated With Pearl Attributes in the Silver-Lip Pearl Oyster, Pinctada maxima. PMID:33488672
HELQ and EGR3 expression correlate with IGHV mutation status and prognosis in chronic lymphocytic leukemia. PMID:33485349
A mixed community of skin microbiome representatives influences cutaneous processes more than individual members. PMID:33482907
Gene co-expression network analysis of Trypanosoma brucei in tsetse fly vector. PMID:33482903
BSR-Seq analysis provides insights into the cold stress response of Actinidia arguta F1 populations. PMID:33482717
The BMP signaling gradient is interpreted through concentration thresholds in dorsal-ventral axial patterning. PMID:33481775
The Hunt for Ancient Prions: Archaeal Prion-Like Domains Form Amyloid-Based Epigenetic Elements. PMID:33480998
Likelihood ratio statistics for gene set enrichment in Alzheimer's disease pathways. PMID:33480182
Transcriptome profiling of cells exposed to particular and intense electromagnetic radiation emitted by the "SG-III" prototype laser facility. PMID:33479397
Integrative multiomics analysis of Premolis semirufa caterpillar venom in the search for molecules leading to a joint disease. PMID:33479267
Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients. PMID:33479266
Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery. PMID:33479222
An empirical meta-analysis of the life sciences linked open data on the web. PMID:33479214
Potential interactions between the TBX4-FGF10 and SHH-FOXF1 signaling during human lung development revealed using ChIP-seq. PMID:33478486
Effect of Aging on Homeostasis in the Soft Tissue of the Periodontium: A Narrative Review. PMID:33477537
The complete mitochondrial genome of sponge Tethya sp. (Demospongiae, Tethyida, Tethyidae). PMID:33473525
Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility. PMID:33472045
Computational Functional Genomics-Based AmpliSeq™ Panel for Next-Generation Sequencing of Key Genes of Pain. PMID:33467215
RNA-Seq transcriptome analysis of ileum in Taiping chicken supplemented with the dietary probiotic. PMID:33462736
Identifying protein subcellular localisation in scientific literature using bidirectional deep recurrent neural network. PMID:33462256
Auxin is involved in arbuscular mycorrhizal fungi-promoted tomato growth and NADP-malic enzymes expression in continuous cropping substrates. PMID:33461504
HIV Protein Tat Induces Macrophage Dysfunction and Atherosclerosis Development in Low-Density Lipoprotein Receptor-Deficient Mice. PMID:33459922
Establishment and application of information resource of mutant mice in RIKEN BioResource Research Center. PMID:33455583
Infection trains the host for microbiota-enhanced resistance to pathogens. PMID:33453153
A systems-level gene regulatory network model for Plasmodium falciparum. PMID:33450011
A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer. PMID:33447827
Ontologies relevant to behaviour change interventions: a method for their development. PMID:33447665
Changes on proteomic and metabolomic profile in serum of mice induced by chronic exposure to tramadol. PMID:33446901
HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow. PMID:33446832
Late p65 nuclear translocation in glioblastoma cells indicates non-canonical TLR4 signaling and activation of DNA repair genes. PMID:33446690
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies. PMID:33446646
An Integrative Transcriptomic Analysis of Systemic Juvenile Idiopathic Arthritis for Identifying Potential Genetic Markers and Drug Candidates. PMID:33445803
Knowledge Network Embedding of Transcriptomic Data from Spaceflown Mice Uncovers Signs and Symptoms Associated with Terrestrial Diseases. PMID:33445483
Diverse Taxonomies for Diverse Chemistries: Enhanced Representation of Natural Product Metabolism in UniProtKB. PMID:33445429
Transcript levels of keratin 1/5/6/14/15/16/17 as potential prognostic indicators in melanoma patients. PMID:33441834
Multiplex gene and phenotype network to characterize shared genetic pathways of epilepsy and autism. PMID:33441621
Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection. PMID:33441564
Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease. PMID:33441415
Longitudinal saliva omics responses to immune perturbation: a case study. PMID:33436912
Post-transcriptional circadian regulation in macrophages organizes temporally distinct immunometabolic states. PMID:33436377
A modular master regulator landscape controls cancer transcriptional identity. PMID:33434495
Identification of loci associated with susceptibility to bovine paratuberculosis and with the dysregulation of the MECOM, eEF1A2, and U1 spliceosomal RNA expression. PMID:33432064
Novel circRNA discovery in sheep shows evidence of high backsplice junction conservation. PMID:33432020
Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism. PMID:33431991
A systems pharmacology approach to identify the autophagy-inducing effects of Traditional Persian medicinal plants. PMID:33431946
Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity. PMID:33431859
Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patients. PMID:33431054
A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions. PMID:33431024
Mapping the SARS-CoV-2-Host Protein-Protein Interactome by Affinity Purification Mass Spectrometry and Proximity-Dependent Biotin Labeling: A Rational and Straightforward Route to Discover Host-Directed Anti-SARS-CoV-2 Therapeutics. PMID:33430309
A novel Foxp3-related immune prognostic signature for glioblastoma multiforme based on immunogenomic profiling. PMID:33429364
Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR. PMID:33428936
Construction of an mRNA-miRNA-lncRNA network prognostic for triple-negative breast cancer. PMID:33428596
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction. PMID:33426377
Methods for isolation and transcriptional profiling of individual cells from the human heart. PMID:33426328
miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells. PMID:33425897
ENPP4 overexpression is associated with no recovery from Barrett's esophagus. PMID:33425094
Selective Sweeps Lead to Evolutionary Success in an Amazonian Hyperdominant Palm. PMID:33424928
Integration of full-length transcriptomics and targeted metabolomics to identify benzylisoquinoline alkaloid biosynthetic genes in Corydalis yanhusuo. PMID:33423040
Re-purposing software for functional characterization of the microbiome. PMID:33422152
Biotin Proximity Labeling for Protein-Protein Interaction Discovery: The BioID Method. PMID:33421001
Prognostic gene expression signatures of breast cancer are lacking a sensible biological meaning. PMID:33420139
Identifying the miRNA Signature Association with Aging-Related Senescence in Glioblastoma. PMID:33419230
An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence. PMID:33417832
The iPPI-DB initiative: A Community-centered database of Protein-Protein Interaction modulators. PMID:33416858
PC2P: Parameter-free network-based prediction of protein complexes. PMID:33416831
Candidate regulators and target genes of drought stress in needles and roots of Norway spruce. PMID:33416078
Integrative analysis of differential circular RNA and long non-coding RNA profiles and associated competing endogenous RNA networks in esophageal squamous cell carcinoma. PMID:33415515
Alcohol use disorder causes global changes in splicing in the human brain. PMID:33414398
HiDeF: identifying persistent structures in multiscale 'omics data. PMID:33413539
Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2. PMID:33413422
Transcriptomic analysis identifies organ-specific metastasis genes and pathways across different primary sites. PMID:33413400
Computational analysis to repurpose drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2. PMID:33413329
Evaluation of the potential of Pap test fluid and cervical swabs to serve as clinical diagnostic biospecimens for the detection of ovarian cancer by mass spectrometry-based proteomics. PMID:33413078
Integration of gene expression data identifies key genes and pathways in colorectal cancer. PMID:33411100
PM4NGS, a project management framework for next-generation sequencing data analysis. PMID:33410471
Machine Learning Models to Predict Primary Sites of Metastatic Cervical Carcinoma From Unknown Primary. PMID:33408743
Identification of Core Genes Involved in the Metastasis of Clear Cell Renal Cell Carcinoma. PMID:33408516
Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms. PMID:33407182
Transcriptional response of Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. leaves grown under full and partial daylight conditions. PMID:33407099
Label-free proteomic analysis of serum exosomes from paroxysmal atrial fibrillation patients. PMID:33407078
An Integrated Platform for Skin Cancer Heterogenous and Multilayered Data Management. PMID:33404959
Identification of Seven Cell Cycle-Related Genes with Unfavorable Prognosis and Construction of their TF-miRNA-mRNA regulatory network in Breast Cancer. PMID:33403032
Relationships Between Vitamin D Status and Cytokine: Results from Interferon-Based Therapy in Non-Cirrhotic, Treatment-Naïve Patients with Chronic Hepatitis C Infection. PMID:33402842
Identification and validation of an immune-related gene signature predictive of overall survival in colon cancer. PMID:33401247
Restoration of type I interferon signaling in intrahepatically primed CD8+ T cells promotes functional differentiation. PMID:33400688
Genome sequencing and functional annotation of Bacillus sp. strain BS-Z15 isolated from cotton rhizosphere soil having antagonistic activity against Verticillium dahliae. PMID:33399892
The Biological Meaning of Radiomic Features. PMID:33399513
TriRNSC: triclustering of gene expression microarray data using restricted neighbourhood search. PMID:33399096
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis. PMID:33398403
Computationally predicted SARS-COV-2 encoded microRNAs target NFKB, JAK/STAT and TGFB signaling pathways. PMID:33398248
The Rcs stress response inversely controls surface and CRISPR-Cas adaptive immunity to discriminate plasmids and phages. PMID:33398095
Analysing the mechanism of mitochondrial oxidation-induced cell death using a multifunctional iridium(III) photosensitiser. PMID:33397915
Whole-Transcriptome RNA Sequencing Reveals the Global Molecular Responses and CeRNA Regulatory Network of mRNAs, lncRNAs, miRNAs and circRNAs in Response to Salt Stress in Sugar Beet (Beta vulgaris). PMID:33396637
Personalized beyond Precision: Designing Unbiased Gold Standards to Improve Single-Subject Studies of Personal Genome Dynamics from Gene Products. PMID:33396440
Transcriptomic Analysis of a Diabetic Skin-Humanized Mouse Model Dissects Molecular Pathways Underlying the Delayed Wound Healing Response. PMID:33396192
Metagenomics survey unravels diversity of biogas microbiomes with potential to enhance productivity in Kenya. PMID:33395690
DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3. PMID:33393494
Immunological Role and Prognostic Value of APBB1IP in Pan-Cancer Analysis. PMID:33391455
Specific MiRNAs in naïve T cells associated with Hepatitis C Virus-induced Hepatocellular Carcinoma. PMID:33391397
RNA-Seq used to identify ipsdienone reductase (IDONER): A novel monoterpene carbon-carbon double bond reductase central to Ips confusus pheromone production. PMID:33388375
IFI27 may predict and evaluate the severity of respiratory syncytial virus infection in preterm infants. PMID:33388093
The Interactome of Cancer-Related Lysyl Oxidase and Lysyl Oxidase-Like Proteins. PMID:33383846
The status of causality in biological databases: data resources and data retrieval possibilities to support logical modeling. PMID:33378765
Effect of let-7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinoma. PMID:33376529
Identifying an Eight-Gene Signature to Optimize Overall Survival Prediction of Esophageal Adenocarcinoma Using Bioinformatics Analysis of ceRNA Network. PMID:33376353
Application of Biological Domain Knowledge Based Feature Selection on Gene Expression Data. PMID:33374969
Novel therapeutic compounds for prostate adenocarcinoma treatment: An analysis using bioinformatic approaches and the CMap database. PMID:33371142
Metric Labeling and Semimetric Embedding for Protein Annotation Prediction. PMID:33370163
Large-fragment insertion activates gene GaFZ (Ga08G0121) and is associated with the fuzz and trichome reduction in cotton (Gossypium arboreum). PMID:33369825
FIGNL1 promotes non‑small cell lung cancer cell proliferation. PMID:33367932
Proteome of the Triatomine Digestive Tract: From Catalytic to Immune Pathways; Focusing on Annexin Expression. PMID:33363206
iTRAQ-Based Phosphoproteomic Analysis of Toxoplasma gondii Tachyzoites Provides Insight Into the Role of Phosphorylation for its Invasion and Egress. PMID:33363051
Transcriptome Analysis of Juvenile Tilapia (Oreochromis niloticus) Blood, Fed With Different Concentrations of Resveratrol. PMID:33362577
Comprehensive Profiling of Gene Expression in the Cerebral Cortex and Striatum of BTBRTF/ArtRbrc Mice Compared to C57BL/6J Mice. PMID:33362469
Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness. PMID:33362275
Salmonella enterica Serovars Dublin and Enteritidis Comparative Proteomics Reveals Differential Expression of Proteins Involved in Stress Resistance, Virulence, and Anaerobic Metabolism. PMID:33361201
A primer for generating and using transcriptome data and gene sets. PMID:33361089
Global insights to drought stress perturbed genes in oat (Avena sativa L.) seedlings using RNA sequencing. PMID:33356830
Knowledge Organization Systems for Systematic Chemical Assessments. PMID:33356525
Generation of an Interactome for the Tetratricopeptide Repeat Domain of O-GlcNAc Transferase Indicates a Role for the Enzyme in Intellectual Disability. PMID:33356293
Comparative genomics reveals dynamic genome evolution in host specialist ectomycorrhizal fungi. PMID:33355923
IiWRKY34 positively regulates yield, lignan biosynthesis and stress tolerance in Isatis indigotica. PMID:33354511
Fully Automated Sample Processing and Analysis Workflow for Low-Input Proteome Profiling. PMID:33352054
Multi-resolution visualization and analysis of biomolecular networks through hierarchical community detection and web-based graphical tools. PMID:33351828
ARPIR: automatic RNA-Seq pipelines with interactive report. PMID:33349239
Tumors Widely Express Hundreds of Embryonic Germline Genes. PMID:33348709
A review on viral data sources and search systems for perspective mitigation of COVID-19. PMID:33348368
Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration. PMID:33347974
A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression. PMID:33346941
Identification of Key Modules and Hub Genes Involved in Esophageal Squamous Cell Carcinoma Tumorigenesis Using WCGNA. PMID:33345608
Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer. PMID:33345281
Ubiquitin-Like Modifier Activating Enzyme 1 as a Novel Diagnostic and Prognostic Indicator That Correlates With Ferroptosis and the Malignant Phenotypes of Liver Cancer Cells. PMID:33344241
Comprehensive analysis of circRNA expression profiles and circRNA-associated competing endogenous RNA networks in IgA nephropathy. PMID:33344076
Identification of significant genes signatures and prognostic biomarkers in cervical squamous carcinoma via bioinformatic data. PMID:33344075
A Novel Family of Acinetobacter Mega-Plasmids Are Disseminating Multi-Drug Resistance Across the Globe While Acquiring Location-Specific Accessory Genes. PMID:33343549
Episodic Decrease in Temperature Increases mcy Gene Transcription and Cellular Microcystin in Continuous Cultures of Microcystis aeruginosa PCC 7806. PMID:33343544
Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism. PMID:33339897
Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells. PMID:33338397
Screening and Identification of Prognostic Tumor-Infiltrating Immune Cells and Genes of Endometrioid Endometrial Adenocarcinoma: Based on The Cancer Genome Atlas Database and Bioinformatics. PMID:33335850
Upregulation of 5'-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor. PMID:33335292
Cerina: systematic circRNA functional annotation based on integrative analysis of ceRNA interactions. PMID:33335165
Biological and physical approaches on the role of piplartine (piperlongumine) in cancer. PMID:33335138
The identification of co-expressed gene modules in Streptococcus pneumonia from colonization to infection to predict novel potential virulence genes. PMID:33334315
GAS2L1 Is a Potential Biomarker of Circulating Tumor Cells in Pancreatic Cancer. PMID:33333841
A Machine Learning Approach for Tracing Tumor Original Sites With Gene Expression Profiles. PMID:33330438
CD8+ T Cell Co-Expressed Genes Correlate With Clinical Phenotype and Microenvironments of Urothelial Cancer. PMID:33330025
Identification of Tumor Microenvironment-Related Prognostic Biomarkers in Luminal Breast Cancer. PMID:33329695
Creation of bladder assembloids mimicking tissue regeneration and cancer. PMID:33328632
A chromosome-scale reference genome of Lobularia maritima, an ornamental plant with high stress tolerance. PMID:33328471
Expression and Possible Molecular Mechanisms of microRNA-205-5p in Patients With Head and Neck Squamous Cell Carcinoma. PMID:33327871
Identification of Hub Genes of Mesio Temporal Lobe Epilepsy and Prognostic Biomarkers of Brain Low-grade Gliomas Based on Bioinformatics Analysis. PMID:33327771
Baseline SUVmax is related to tumor cell proliferation and patient outcome in follicular lymphoma. PMID:33327711
Comprehensive Transcriptomic Analysis Reveals Dysregulated Competing Endogenous RNA Network in Endocrine Resistant Breast Cancer Cells. PMID:33324567
Genetic Determinants of Gating Functions: Do We Get Closer to Understanding Schizophrenia Etiopathogenesis? PMID:33324248
Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene. PMID:33323528
Characterisation of gene and pathway expression in stabilised blood from children with coeliac disease. PMID:33323471
PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence. PMID:33320871
Distinct genomic profiles of gestational choriocarcinoma, a unique cancer of pregnant tissues. PMID:33319857
Outlier concepts auditing methodology for a large family of biomedical ontologies. PMID:33319713
Towards semantic interoperability: finding and repairing hidden contradictions in biomedical ontologies. PMID:33319712
Analysis of readability and structural accuracy in SNOMED CT. PMID:33319711
Missing lateral relationships in top-level concepts of an ontology. PMID:33319709
Extending import detection algorithms for concept import from two to three biomedical terminologies. PMID:33319702
Genome-wide correlation analysis to identify amplitude regulators of circadian transcriptome output. PMID:33318596
Olfactomedin 4 mediation of prostate stem/progenitor-like cell proliferation and differentiation via MYC. PMID:33318499
Identification of long non-coding RNA signatures for squamous cell carcinomas and adenocarcinomas. PMID:33318305
Hearing impairment due to Mir183/96/182 mutations suggests both loss and gain of function effects. PMID:33318051
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner. PMID:33315488
Hierarchical Canonical Correlation Analysis Reveals Phenotype, Genotype, and Geoclimate Associations in Plants. PMID:33313545
Computing on Phenotypic Descriptions for Candidate Gene Discovery and Crop Improvement. PMID:33313544
A bioinformatics analysis on the potential role of ACE2 in cardiac impairment of patients with coronavirus disease 2019. PMID:33313148
GWAS and Beyond: Using Omics Approaches to Interpret SNP Associations. PMID:33312764
Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time. PMID:33307245
The leukocyte non-coding RNA landscape in critically ill patients with sepsis. PMID:33305733
Immunogenetic and tolerance strategies against a novel parasitoid of wild field crickets. PMID:33304539
Draft Genome Sequence of Lactobacillus salivarius KZ-NCB, Isolated from Chicken Cecum. PMID:33303665
GCNG: graph convolutional networks for inferring gene interaction from spatial transcriptomics data. PMID:33303016
Composition and origin of lung fluid proteome in premature infants and relationship to respiratory outcome. PMID:33301538
Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing. PMID:33300025
ideal: an R/Bioconductor package for interactive differential expression analysis. PMID:33297942
Identification of an RNA binding protein-related gene signature in hepatocellular carcinoma patients. PMID:33297932
Integrated Physiological and Transcriptomic Analyses Reveal a Regulatory Network of Anthocyanin Metabolism Contributing to the Ornamental Value in a Novel Hybrid Cultivar of Camellia Japonica. PMID:33297392
COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type-2 and PDE4 gene expression in sputum. PMID:33295083
An Integrated Bioinformatic Analysis of the S100 Gene Family for the Prognosis of Colorectal Cancer. PMID:33294444
Network Pharmacology-Based Study on the Mechanism of Gegen Qinlian Decoction against Colorectal Cancer. PMID:33294000
Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains. PMID:33293533
Donkey genomes provide new insights into domestication and selection for coat color. PMID:33293529
PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API. PMID:33290554
Expression patterns and prognostic values of the cyclin-dependent kinase 1 and cyclin A2 gene cluster in pancreatic adenocarcinoma. PMID:33290118
Bioinformatic analysis of key pathways and genes involved in pediatric atopic dermatitis. PMID:33289509
Hidden in plain sight: The effects of BCG vaccination in the COVID-19 pandemic. PMID:33289122
Comparative transcriptome analysis of three gonadal development stages reveals potential genes involved in gametogenesis of the fluted giant clam (Tridacna squamosa). PMID:33287701
Transcriptome Remodeling in Gradual Development of Inverse Resistance between Paclitaxel and Cisplatin in Ovarian Cancer Cells. PMID:33287223
TMEA: A Thermodynamically Motivated Framework for Functional Characterization of Biological Responses to System Acclimation. PMID:33286800
Fifteen Years of Gene Set Analysis for High-Throughput Genomic Data: A Review of Statistical Approaches and Future Challenges. PMID:33286201
Chronic circadian shift leads to adipose tissue inflammation and fibrosis. PMID:33285245
Assembly of the non-heading pak choi genome and comparison with the genomes of heading Chinese cabbage and the oilseed yellow sarson. PMID:33283404
TTK, CDC25A, and ESPL1 as Prognostic Biomarkers for Endometrial Cancer. PMID:33282948
Identification of Dysregulated Genes for Late-Onset Alzheimer's Disease Using Gene Expression Data in Brain. PMID:33282526
Network Pharmacology Identifies the Mechanisms of Action of Tongxie Anchang Decoction in the Treatment of Irritable Bowel Syndrome with Diarrhea Predominant. PMID:33281910
Comparative Genomics Analysis Provides New Strategies for Bacteriostatic Ability of Bacillus velezensis HAB-2. PMID:33281792
Role of COL3A1 and POSTN on Pathologic Stages of Esophageal Cancer. PMID:33280513
Replaying the evolutionary tape to investigate subgenome dominance in allopolyploid Brassica napus. PMID:33280122
Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity. PMID:33278344
Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity. PMID:33278339
A Novel Proximity Biotinylation Assay Based on the Self-Associating Split GFP1-10/11. PMID:33276494
Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration-resistant prostate cancer. PMID:33275817
High levels of glucose alter Physcomitrella patens metabolism and trigger a differential proteomic response. PMID:33275616
Urinary vitronectin identifies patients with high levels of fibrosis in kidney grafts. PMID:33275196
Informatics Inference of Exercise-Induced Modulation of Brain Pathways Based on Cerebrospinal Fluid Micro-RNAs in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. PMID:33274349
CovMulNet19, Integrating Proteins, Diseases, Drugs, and Symptoms: A Network Medicine Approach to COVID-19. PMID:33274348
Screening of T Cell-Related Long Noncoding RNA-MicroRNA-mRNA Regulatory Networks in Non-Small-Cell Lung Cancer. PMID:33274216
Identification of Monotonically Differentially Expressed Genes across Pathologic Stages for Cancers. PMID:33273919
NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet. PMID:33273482
The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis. PMID:33270882
COVID-19 Knowledge Extractor (COKE): A Tool and a Web Portal to Extract Drug - Target Protein Associations from the CORD-19 Corpus of Scientific Publications on COVID-19. PMID:33269341
Reprogramming to recover youthful epigenetic information and restore vision. PMID:33268865
Humoral immune responses mediate the development of a restrictive phenotype of chronic lung allograft dysfunction. PMID:33268593
Supervised and Unsupervised End-to-End Deep Learning for Gene Ontology Classification of Neural In Situ Hybridization Images. PMID:33266936
Comparative Analysis of the Global Transcriptomic Response to Oxidative Stress of Bacillus anthracis htrA-Disrupted and Parental Wild Type Strains. PMID:33265965
YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction. PMID:33264286
Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure. PMID:33262328
Transcriptome Sequencing and Comparative Analysis of Amphoteric ESCs and PGCs in Chicken (Gallus gallus). PMID:33261034
A hybrid approach toward biomedical relation extraction training corpora: combining distant supervision with crowdsourcing. PMID:33258966
Regulators of TNFα mediated insulin resistance elucidated by quantitative proteomics. PMID:33257747
Wide-ranging transcriptomic analysis of Poncirus trifoliata, Citrus sunki, Citrus sinensis and contrasting hybrids reveals HLB tolerance mechanisms. PMID:33257732
What Can Machine Learning Approaches in Genomics Tell Us about the Molecular Basis of Amyotrophic Lateral Sclerosis? PMID:33256133
MiR-215-5p Reduces Liver Metastasis in an Experimental Model of Colorectal Cancer through Regulation of ECM-Receptor Interactions and Focal Adhesion. PMID:33255928
Essential gene prediction using limited gene essentiality information-An integrative semi-supervised machine learning strategy. PMID:33253254
Mining GWAS and eQTL data for CF lung disease modifiers by gene expression imputation. PMID:33253230
Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host. PMID:33252330
Dataset of full-length transcriptome assembly and annotation of apocynum venetum using pacbio sequel II. PMID:33251304
Identification of hsa-miR-1275 as a Novel Biomarker Targeting MECP2 for Human Epilepsy of Unknown Etiology. PMID:33251277
Transferrin Receptor Functionally Marks Thermogenic Adipocytes. PMID:33251209
Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome. PMID:33247132
RNA-mediated control of cell shape modulates antibiotic resistance in Vibrio cholerae. PMID:33247102
Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages. PMID:33246411
MicroRNA-based regulation of Aurora A kinase in breast cancer. PMID:33245732
Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer. PMID:33242424
Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact. PMID:33242417
MutRank: an R shiny web-application for exploratory targeted mutual rank-based coexpression analyses integrated with user-provided supporting information. PMID:33240618
Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer. PMID:33240431
Functional characterisation of the transcriptome from leaf tissue of the fluoroacetate-producing plant, Dichapetalum cymosum, in response to mechanical wounding. PMID:33239700
Improving existing analysis pipeline to identify and analyze cancer driver genes using multi-omics data. PMID:33239644
Integrative genomic meta-analysis reveals novel molecular insights into cystic fibrosis and ΔF508-CFTR rescue. PMID:33239626
Identifying transcriptomic correlates of histology using deep learning. PMID:33237966
A thorough analysis of the contribution of experimental, derived and sequence-based predicted protein-protein interactions for functional annotation of proteins. PMID:33237964
Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts. PMID:33237278
Insights into amphicarpy from the compact genome of the legume Amphicarpaea edgeworthii. PMID:33236503
Anti-inflammatory activity of Radix Angelicae biseratae in the treatment of osteoarthritis determined by systematic pharmacology and in vitro experiments. PMID:33235614
Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity. PMID:33235355
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals. PMID:33235224
CD74, a novel predictor for bronchopulmonary dysplasia in preterm infants. PMID:33235138
Donor-Specific Transcriptomic Analysis of Alzheimer's Disease-Associated Hypometabolism Highlights a Unique Donor, Ribosomal Proteins and Microglia. PMID:33234543
The Mediation of miR-34a/miR-449c for Immune Cytokines in Acute Cold/Heat-Stressed Broiler Chicken. PMID:33233727
Physiological Changes in Barley mlo-11 Powdery Mildew Resistance Conditioned by Tandem Repeat Copy Number. PMID:33233522
Epigenome-wide association scan identifies methylation sites associated with HIV infection. PMID:33232214
NECAB1 and NECAB2 are Prevalent Calcium-Binding Proteins of CB1/CCK-Positive GABAergic Interneurons. PMID:33230531
Conjoint Feature Representation of GO and Protein Sequence for PPI Prediction Based on an Inception RNN Attention Network. PMID:33230427
Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. PMID:33230303
Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination. PMID:33229445
Chicken cecal DNA methylome alteration in the response to Salmonella enterica serovar Enteritidis inoculation. PMID:33225883
Exploring biomarkers and therapeutic targets for pressure overload induced heart failure based on microarray data. PMID:33224746
Comprehensive proteomic atlas of skin biomatrix scaffolds reveals a supportive microenvironment for epidermal development. PMID:33224464
Investigation of the Potential Mechanism Governing the Effect of the Shen Zhu San on COVID-19 by Network Pharmacology. PMID:33224256
In-depth transcriptomic analyses of LncRNA and mRNA expression in the hippocampus of APP/PS1 mice by Danggui-Shaoyao-San. PMID:33221745
MolluscDB: an integrated functional and evolutionary genomics database for the hyper-diverse animal phylum Mollusca. PMID:33219670
A network-based comparative framework to study conservation and divergence of proteomes in plant phylogenies. PMID:33219668
Identification of Natural CRISPR Systems and Targets in the Human Microbiome. PMID:33217332
Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia. PMID:33217134
Predicted rat interactome database and gene set linkage analysis. PMID:33216897
Genome Sequence of Klebsiella pneumoniae YBQ, a Clinical Strain Isolated from the Sputum of a Patient with Severe Pneumonia. PMID:33214313
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy. PMID:33212010
Prognostic Implication of a Metabolism-Associated Gene Signature in Lung Adenocarcinoma. PMID:33209981
Leaf shape in Populus tremula is a complex, omnigenic trait. PMID:33209260
Machine learning approaches reveal genomic regions associated with sugarcane brown rust resistance. PMID:33208862
ClusterM: a scalable algorithm for computational prediction of conserved protein complexes across multiple protein interaction networks. PMID:33208103
Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva. PMID:33207190
A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits. PMID:33207182
Genome-wide profiling of alternative splicing genes in hybrid poplar (P.alba×P.glandulosa cv.84K) leaves. PMID:33206683
DeepPheno: Predicting single gene loss-of-function phenotypes using an ontology-aware hierarchical classifier. PMID:33206638
LINC01235-TWIST2 feedback loop facilitates epithelial-mesenchymal transition in gastric cancer by inhibiting THBS2. PMID:33206629
Urinary glycoproteins associated with aggressive prostate cancer. PMID:33204318
Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data. PMID:33203837
Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq. PMID:33203447
Microarray expression profile analysis of circular RNAs and their potential regulatory role in bladder carcinoma. PMID:33200221
Genome-Wide Functional Screen for Calcium Transients in Escherichia coli Identifies Increased Membrane Potential Adaptation to Persistent DNA Damage. PMID:33199283
RBP2GO: a comprehensive pan-species database on RNA-binding proteins, their interactions and functions. PMID:33196814
NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants. PMID:33196801
A comparison of mRNA and circRNA expression between squamous cell carcinoma and adenocarcinoma of the lungs. PMID:33196759
Transcriptomic Data Analyses Reveal a Reprogramed Lipid Metabolism in HCV-Derived Hepatocellular Cancer. PMID:33195224
Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids. PMID:33195205
Proteomic Analysis of Exosome-Like Vesicles Isolated From Saliva of the Tick Haemaphysalis longicornis. PMID:33194791
Integrated transcriptome meta-analysis of pancreatic ductal adenocarcinoma and matched adjacent pancreatic tissues. PMID:33194391
Involvement of the Wnt/β-Catenin signaling pathway in the heterogenous nuclear ribonucleoprotein K-driven inhibition of proliferation and migration in head and neck squamous cell carcinoma. PMID:33193854
Transcriptome Analyses of β-Thalassemia -28(A>G) Mutation Using Isogenic Cell Models Generated by CRISPR/Cas9 and Asymmetric Single-Stranded Oligodeoxynucleotides (assODNs). PMID:33193694
Recurrent Drought Conditions Enhance the Induction of Drought Stress Memory Genes in Glycine max L. PMID:33193691
The Cyclically Seasonal Drosophila subobscura Inversion O7 Originated From Fragile Genomic Sites and Relocated Immunity and Metabolic Genes. PMID:33193649
Identification of RNA Transcript Makers Associated With Prognosis of Kidney Renal Clear Cell Carcinoma by a Competing Endogenous RNA Network Analysis. PMID:33193613
Identification of Potential Core Genes Associated With the Progression of Stomach Adenocarcinoma Using Bioinformatic Analysis. PMID:33193601
Hub Genes Identification in a Murine Model of Allergic Rhinitis Based on Bioinformatics Analysis. PMID:33193578
Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts. PMID:33193165
Inflammatory Response of Ischemic Tolerance in Circulating Plasma: Preconditioning-Induced by Transient Ischemic Attack (TIA) Phenomena in Acute Ischemia Patients (AIS). PMID:33192985
Embedding-based Silhouette community detection. PMID:33191975
Molecular estimation of neurodegeneration pseudotime in older brains. PMID:33188183
Dedifferentiation and neuronal repression define familial Alzheimer's disease. PMID:33188013
Virtual screening and network pharmacology-based synergistic mechanism identification of multiple components contained in Guanxin V against coronary artery disease. PMID:33187508
Quantitative Interactomics of Lck-TurboID in Living Human T Cells Unveils T Cell Receptor Stimulation-Induced Proximal Lck Interactors. PMID:33185455
The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation. PMID:33184237
Gene Expression Signatures in AML-12 Hepatocyte Cells upon Dengue virus Infection and Acetaminophen Treatment. PMID:33182673
A Collection of Benchmark Data Sets for Knowledge Graph-based Similarity in the Biomedical Domain. PMID:33181823
Establishment of immune prognostic signature and analysis of prospective molecular mechanisms in childhood osteosarcoma patients. PMID:33181717
FunRes: resolving tissue-specific functional cell states based on a cell-cell communication network model. PMID:33179736
ID1 As a Prognostic Biomarker and Promising Drug Target Plays a Pivotal Role in Deterioration of Clear Cell Renal Cell Carcinoma. PMID:33178820
Bioinformatic Analysis Identifies Potential Key Genes in the Pathogenesis of Melanoma. PMID:33178610
Prolonged Targeted Cardiovascular Epidural Stimulation Improves Immunological Molecular Profile: A Case Report in Chronic Severe Spinal Cord Injury. PMID:33177997
Avian Immunome DB: an example of a user-friendly interface for extracting genetic information. PMID:33176685
Decoding myofibroblast origins in human kidney fibrosis. PMID:33176333
Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10. PMID:33175605
COVID-KOP: integrating emerging COVID-19 data with the ROBOKOP database. PMID:33175089
Anti‑inflammatory mechanism of berberine on lipopolysaccharide‑induced IEC‑18 models based on comparative transcriptomics. PMID:33174609
Co‑expression network analysis identified specific miRNAs and genes in association with slow‑transit constipation. PMID:33174045
Upregulated lnc‑HRK‑2:1 prompts nucleus pulposus cell senescence in intervertebral disc degeneration. PMID:33174041
Identification of inflammation‑associated circulating long non‑coding RNAs and genes in intracranial aneurysm rupture‑induced subarachnoid hemorrhage. PMID:33174039
Using mRNA deep sequencing to analyze differentially expressed genes during Panax notoginseng saponin treatment of ischemic stroke. PMID:33173991
Integrated microarray analysis of key genes and a miRNA‑mRNA regulatory network of early‑onset preeclampsia. PMID:33173953
Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy. PMID:33173052
Transcriptional Effects of Psychoactive Drugs on Genes Involved in Neurogenesis. PMID:33172123
Deciphering cell-cell interactions and communication from gene expression. PMID:33168968
Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease. PMID:33168134
A semi-supervised Bayesian approach for simultaneous protein sub-cellular localisation assignment and novelty detection. PMID:33166281
Systematic Analysis of Protein-Protein and Gene-Environment Interactions to Decipher the Cognitive Mechanisms of Autism Spectrum Disorder. PMID:33165687
CYP27B1 Downregulation: A New Molecular Mechanism Regulating EZH2 in Ovarian Cancer Tumorigenicity. PMID:33163485
Expression Changes in Epigenetic Gene Pathways Associated With One-Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non-Typical Neurodevelopment. PMID:33159718
CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model. PMID:33159168
Bioinformatics-based identification of miRNA-, lncRNA-, and mRNA-associated ceRNA networks and potential biomarkers for preeclampsia. PMID:33157942
CLAVATA Signaling Ensures Reproductive Development in Plants across Thermal Environments. PMID:33157018
Lipopolysaccharide triggers different transcriptional signatures in taurine and indicine cattle macrophages: Reactive oxygen species and potential outcomes to the development of immune response to infections. PMID:33156842
TCRD and Pharos 2021: mining the human proteome for disease biology. PMID:33156327
Argonaut: A Web Platform for Collaborative Multi-omic Data Visualization and Exploration. PMID:33154995
Deep learning approach for predicting functional Z-DNA regions using omics data. PMID:33154517
Full function of exon junction complex factor, Rbm8a, is critical for interneuron development. PMID:33154347
The Transcriptome of Cunninghamia lanceolata male/female cone reveal the association between MIKC MADS-box genes and reproductive organs development. PMID:33153428
RNA Sequencing Reveals Diverse Functions of Amniotic Fluid Neutrophils and Monocytes/Macrophages in Intra-Amniotic Infection. PMID:33152737
DrugCentral 2021 supports drug discovery and repositioning. PMID:33151287
Constitution of a comprehensive phytochemical profile and network pharmacology based investigation to decipher molecular mechanisms of Teucrium polium L. in the treatment of type 2 diabetes mellitus. PMID:33150068
In-depth transcriptome reveals the potential biotechnological application of Bothrops jararaca venom gland. PMID:33149734
Desmoglein 3 and Keratin 14 for Distinguishing Between Lung Adenocarcinoma and Lung Squamous Cell Carcinoma. PMID:33149622
Circulating miR-1246 in the Progression of Chronic Obstructive Pulmonary Disease (COPD) in Patients from the BODE Cohort. PMID:33149570
Singular manifolds of proteomic drivers to model the evolution of inflammatory bowel disease status. PMID:33149233
Loss of PHF6 leads to aberrant development of human neuron-like cells. PMID:33149206
Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow. PMID:33149111
Integrated Bioinformatics Analysis of Hub Genes and Pathways Associated with a Compression Model of Spinal Cord Injury in Rats. PMID:33149108
Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses. PMID:33148676
Ubiquitinome Profiling Reveals the Landscape of Ubiquitination Regulation in Rice Young Panicles. PMID:33147495
Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials. PMID:33147277
Exploration in the Mechanism of Kaempferol for the Treatment of Gastric Cancer Based on Network Pharmacology. PMID:33145355
Investigation of hub genes involved in diabetic nephropathy using biological informatics methods. PMID:33145306
The draft genome of the blood pheasant (Ithaginis cruentus): Phylogeny and high-altitude adaptation. PMID:33144976
Transcriptomic profiling of feline teeth highlights the role of matrix metalloproteinase 9 (MMP9) in tooth resorption. PMID:33144645
Container-aided integrative QTL and RNA-seq analysis of Collaborative Cross mice supports distinct sex-oriented molecular modes of response in obesity. PMID:33143653
The Role of Salmonella Genomic Island 4 in Metal Tolerance of Salmonella enterica Serovar I 4,[5],12:i:- Pork Outbreak Isolate USDA15WA-1. PMID:33142960
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis. PMID:33140449
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells. PMID:33140047
Towards a foundational representation of potential drug-drug interaction knowledge. PMID:33139970
Proximity labeling in mammalian cells with TurboID and split-TurboID. PMID:33139955
Bacterial-fungal interactions revealed by genome-wide analysis of bacterial mutant fitness. PMID:33139882
β-Catenin signaling dynamics regulate cell fate in differentiating neural stem cells. PMID:33139571
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids. PMID:33138918
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors. PMID:33137164
Differential transcript usage in the Parkinson's disease brain. PMID:33137089
Quorum Sensing System in Bacteroides thetaiotaomicron Strain Identified by Genome Sequence Analysis. PMID:33134713
High Expression of UBB, RAC1, and ITGB1 Predicts Worse Prognosis among Nonsmoking Patients with Lung Adenocarcinoma through Bioinformatics Analysis. PMID:33134373
The Model of PPARγ-Downregulated Signaling in Psoriasis. PMID:33133175
A Systems Biology Approach to Identifying a Master Regulator That Can Transform the Fast Growing Cellular State to a Slowly Growing One in Early Colorectal Cancer Development Model. PMID:33133158
Identification of the Significant Genes Regulated by Estrogen Receptor in Estrogen Receptor-Positive Breast Cancer and Their Expression Pattern Changes When Tamoxifen or Fulvestrant Resistance Occurs. PMID:33133141
Plasma Proteome Responses in Salmonid Fish Following Immunization. PMID:33133099
Warming Climate Is Reducing the Diversity of Dominant Microbes in the Largest High Arctic Lake. PMID:33133035
Epitope prediction and identification- adaptive T cell responses in humans. PMID:33131981
System-level analyses of keystone genes required for mammalian tooth development. PMID:33128445
Higher miR-543 levels correlate with lower STK31 expression and longer pancreatic cancer survival. PMID:33128354
PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells. PMID:33127860
Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species‑mediated apoptosis by targeting the electron transport chain. PMID:33125107
Characteristic and Phylogenetic Analysis of the Complete Chloroplast Genomes of Three Medicinal Plants of Schisandraceae. PMID:33123569
Transcriptome Profiling-Based Analysis of Carbohydrate-Active Enzymes in Aspergillus terreus Involved in Plant Biomass Degradation. PMID:33123513
Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. PMID:33122739
Paternal reprogramming-escape histone H3K4me3 marks located within promoters of RNA splicing genes. PMID:33119058
Transcriptome and proteome mapping in the sheep atria reveal molecular featurets of atrial fibrillation progression. PMID:33119050
Identification of key genes and pathways for melanoma in the TRIM family. PMID:33118318
A Phylogenetic Rate Parameter Indicates Different Sequence Divergence Patterns in Orthologs and Paralogs. PMID:33118098
Common Adaptive Strategies Underlie Within-Host Evolution of Bacterial Pathogens. PMID:33118035
OsteoBLAST: Computational Routine of Global Molecular Analysis Applied to Biomaterials Development. PMID:33117780
On the Logical Design of a Prototypical Data Lake System for Biological Resources. PMID:33117777
Increased M1 Macrophages Infiltration Correlated With Poor Survival Outcomes and Radiation Response in Gliomas. PMID:33117094
RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis. PMID:33116296
Murine interfollicular epidermal differentiation is gradualistic with GRHL3 controlling progression from stem to transition cell states. PMID:33116143
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells. PMID:33116115
Systematic Investigation of Resistance Evolution to Common Antibiotics Reveals Conserved Collateral Responses across Common Human Pathogens. PMID:33106260
Computational Identification of Human Biological Processes and Protein Sequence Motifs Putatively Targeted by SARS-CoV-2 Proteins Using Protein-Protein Interaction Networks. PMID:33103435
A curated list of genes that affect the plant ionome. PMID:33103043
Genomic and transcriptomic landscapes and evolutionary dynamics of molluscan glycoside hydrolase families with implications for algae-feeding biology. PMID:33101612
Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation. PMID:33101423
Systematic Identification of Hub Genes in Placenta Accreta Spectrum Based on Integrated Transcriptomic and Proteomic Analysis. PMID:33101378
Haplotype Block Analysis Reveals Candidate Genes and QTLs for Meat Quality and Disease Resistance in Chinese Jiangquhai Pig Breed. PMID:33101353
Transcriptomic profile of Pea3 family members reveal regulatory codes for axon outgrowth and neuronal connection specificity. PMID:33097800
Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. PMID:33096023
Meta-analysis of Transcriptomic Data Reveals Pathophysiological Modules Involved with Atrial Fibrillation. PMID:33095430
The efficacy of chemotherapeutic drug combinations may be predicted by concordance of gene response to the single agents. PMID:33093925
Maximized quantitative phosphoproteomics allows high confidence dissection of the DNA damage signaling network. PMID:33093574
A genome-wide association study of severe asthma exacerbations in Latino children and adolescents. PMID:33093117
Transcriptome analysis of Actinoplanes utahensis reveals molecular signature of saccharide impact on acarbose biosynthesis. PMID:33088668
Comparative morphological and transcriptomic analyses reveal chemosensory genes in the poultry red mite, Dermanyssus gallinae. PMID:33087814
De novo transcriptome assembly from the gonads of a scleractinian coral, Euphyllia ancora: molecular mechanisms underlying scleractinian gametogenesis. PMID:33087060
Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network. PMID:33087039
Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs. PMID:33086061
OGEE v3: Online GEne Essentiality database with increased coverage of organisms and human cell lines. PMID:33084874
Integrative Analyses of Genes Associated with Fulminant Type 1 Diabetes. PMID:33083497
Exploration of ovine milk whey proteome during postnatal development using an iTRAQ approach. PMID:33083141
Genomic signatures of globally enhanced gene duplicate accumulation in the megadiverse higher Diptera fueling intralocus sexual conflict resolution. PMID:33083121
Examining the effector mechanisms of Xuebijing injection on COVID-19 based on network pharmacology. PMID:33082858
Mitochondrial-Y chromosome epistasis in Drosophila melanogaster. PMID:33081607
Common gene signatures and key pathways in hypopharyngeal and esophageal squamous cell carcinoma: Evidence from bioinformatic analysis. PMID:33080677
MARS: discovering novel cell types across heterogeneous single-cell experiments. PMID:33077966
Quantifying the distribution of protein oligomerization degree reflects cellular information capacity. PMID:33077848
Predicted functional interactome of Caenorhabditis elegans and a web tool for the functional interpretation of differentially expressed genes. PMID:33076954
SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity. PMID:33075803
Differential Transcription and Alternative Splicing in Cotton Underly Specialized Defense Responses Against Pests. PMID:33072149
No Assembly Required: Using BTyper3 to Assess the Congruency of a Proposed Taxonomic Framework for the Bacillus cereus Group With Historical Typing Methods. PMID:33072050
Comparative Toxicogenomics Database (CTD): update 2021. PMID:33068428
Sexually dimorphic radiogenomic models identify distinct imaging and biological pathways that are prognostic of overall survival in glioblastoma. PMID:33068415
mRNA and miRNA expression profile reveals the role of miR-31 overexpression in neural stem cell. PMID:33067542
Increased RNA editing in maternal immune activation model of neurodevelopmental disease. PMID:33067431
Integrated Analysis of the Transcriptome and Metabolome of Cecropia obtusifolia: A Plant with High Chlorogenic Acid Content Traditionally Used to Treat Diabetes Mellitus. PMID:33066422
Genome Sequencing of Paecilomyces Penicillatus Provides Insights into Its Phylogenetic Placement and Mycoparasitism Mechanisms on Morel Mushrooms. PMID:33065983
Divergent Resistance Mechanisms to Immunotherapy Explain Responses in Different Skin Cancers. PMID:33065980
Circ-Tulp4 promotes β-cell adaptation to lipotoxicity by regulating soat1 expression. PMID:33064661
Identification of fertility-related genes for maize CMS-S via Bulked Segregant RNA-Seq. PMID:33062436
Bioinformatics-Based Identification of a circRNA-miRNA-mRNA Axis in Esophageal Squamous Cell Carcinomas. PMID:33061972
Identification of G2 and S Phase-Expressed-1 as a Potential Biomarker in Patients with Prostate Cancer. PMID:33061616
Exploration of the Potential Biomarkers of Papillary Thyroid Cancer (PTC) Based on RT2 Profiler PCR Arrays and Bioinformatics Analysis. PMID:33061614
Mapping scientific landscapes in UMLS research: a scientometric review. PMID:33059367
During bacteremia, Pseudomonas aeruginosa PAO1 adapts by altering the expression of numerous virulence genes including those involved in quorum sensing. PMID:33057423
Transcriptome sequencing and screening of genes related to sex determination of Trichosanthes kirilowii Maxim. PMID:33057394
Study of the differentially abundant proteins among Leishmania amazonensis, L. braziliensis, and L. infantum. PMID:33057350
The structural variation landscape in 492 Atlantic salmon genomes. PMID:33056985
smORFunction: a tool for predicting functions of small open reading frames and microproteins. PMID:33054771
Monosomy X in Female Mice Influences the Regional Formation and Augments the Severity of Angiotensin II-Induced Aortopathies. PMID:33054396
The Lethal(2)-Essential-for-Life [L(2)EFL] Gene Family Modulates Dengue Virus Infection in Aedes aegypti. PMID:33053895
Cytosolic TaGAPC2 Enhances Tolerance to Drought Stress in Transgenic Arabidopsis Plants. PMID:33053684
IurV, Encoded by ORF VCA0231, Is Involved in the Regulation of Iron Uptake Genes in Vibrio cholerae. PMID:33053678
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. PMID:33052901
Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. PMID:33052137
Identification of potential key genes and miRNAs involved in Hepatoblastoma pathogenesis and prognosis. PMID:33051830
Predicting candidate genes from phenotypes, functions and anatomical site of expression. PMID:33051643
Integrated phosphoproteomic and metabolomic profiling reveals perturbed pathways in the hippocampus of gut microbiota dysbiosis mice. PMID:33051451
Semantic similarity and machine learning with ontologies. PMID:33049044
Maximizing cohesion and separation for detecting protein functional modules in protein-protein interaction networks. PMID:33048996
Prediction of a competing endogenous RNA co-expression network as a prognostic marker in glioblastoma. PMID:33047898
Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta. PMID:33046794
Electricity from lignocellulosic substrates by thermophilic Geobacillus species. PMID:33046790
Agasicles hygrophila attack increases nerolidol synthase gene expression in Alternanthera philoxeroides, facilitating host finding. PMID:33046727
Characterization of the TyrR Regulon in the Rhizobacterium Enterobacter ludwigii UW5 Reveals Overlap with the CpxR Envelope Stress Response. PMID:33046562
Transcriptome analysis revealed misregulated gene expression in blastoderms of interspecific chicken and Japanese quail F1 hybrids. PMID:33044996
RNA sequence analysis of dermal papilla cells' regeneration in 3D culture. PMID:33038058
The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals. PMID:33037820
In vivo mRNA display enables large-scale proteomics by next generation sequencing. PMID:33037152
Bioinformatic Identification of Potential Hub Genes in Muscle-Invasive Bladder Urothelial Carcinoma. PMID:33035117
Decoding the wheat awn transcriptome and overexpressing TaRca1β in rice for heat stress tolerance. PMID:33034884
Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons. PMID:33034629
Global gene expression analyses of the alkamide-producing plant Heliopsis longipes supports a polyketide synthase-mediated biosynthesis pathway. PMID:33033663
A review of protein-protein interaction network alignment: From pathway comparison to global alignment. PMID:33033584
Rewiring of gene expression in circulating white blood cells is associated with pregnancy outcome in heifers (Bos taurus). PMID:33033295
A realism-based approach to an ontological representation of symbiotic interactions. PMID:33032576
Graph-based exploitation of gene ontology using GOxploreR for scrutinizing biological significance. PMID:33028846
Identification of a new pseudogenes/lncRNAs-hsa-miR-26b-5p-COL12A1 competing endogenous RNA network associated with prognosis of pancreatic cancer using bioinformatics analysis. PMID:33027767
Root-Secreted Coumarins and the Microbiota Interact to Improve Iron Nutrition in Arabidopsis. PMID:33027611
Compartment-specific transcriptomics of ozone-exposed murine lungs reveals sex- and cell type-associated perturbations relevant to mucoinflammatory lung diseases. PMID:33026818
Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants. PMID:33025817
A Novel Proteomic Method Reveals NLS Tagging of T-DM1 Contravenes Classical Nuclear Transport in a Model of HER2-Positive Breast Cancer. PMID:33024794
A high-quality chromosome-level genome assembly reveals genetics for important traits in eggplant. PMID:33024567
Transcript Isoforms of SLC7A11-AS1 Are Associated With Varicocele-Related Male Infertility. PMID:33024440
Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases. PMID:33023927
Identification of Parkinson's disease-related pathways and potential risk factors. PMID:33021140
lncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA. PMID:33020484
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage. PMID:33020480
The Differential Composition of Whey Proteomes in Hu Sheep Colostrum and Milk during Different Lactation Periods. PMID:33019658
Development and Validation of a Novel DNA Methylation-Driven Gene Based Molecular Classification and Predictive Model for Overall Survival and Immunotherapy Response in Patients With Glioblastoma: A Multiomic Analysis. PMID:33015072
Pseudo2GO: A Graph-Based Deep Learning Method for Pseudogene Function Prediction by Borrowing Information From Coding Genes. PMID:33014009
Complete Genome Sequencing and Transcriptome Analysis of Nitrogen Metabolism of Succinivibrio dextrinosolvens Strain Z6 Isolated From Dairy Cow Rumen. PMID:33013723
Screening and Identification of Key Biomarkers in Acquired Lapatinib-Resistant Breast Cancer. PMID:33013420
Creating Neuroscientific Knowledge Organization System Based on Word Representation and Agglomerative Clustering Algorithm. PMID:33013345
Mouse Genetic Reference Populations: Cellular Platforms for Integrative Systems Genetics. PMID:33010949
Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium. PMID:33010822
Sex-specific epigenetic profile of inner cell mass of mice conceived in vivo or by IVF. PMID:33010164
Genome-Wide Association Analysis of Neonatal White Matter Microstructure. PMID:33009551
Differential network analysis of bovine muscle reveals changes in gene coexpression patterns in response to changes in maternal nutrition. PMID:33008289
Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling. PMID:33007944
Discovering lethal alleles across the turkey genome using a transmission ratio distortion approach. PMID:33006154
iMDA-BN: Identification of miRNA-disease associations based on the biological network and graph embedding algorithm. PMID:33005302
Full-length transcriptome sequencing analysis and development of EST-SSR markers for the endangered species Populus wulianensis. PMID:33004908
Transcriptomic signatures of cold adaptation and heat stress in the winter ant (Prenolepis imparis). PMID:33002025
Phenotype-genotype comorbidity analysis of patients with rare disorders provides insight into their pathological and molecular bases. PMID:33001999
Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells. PMID:33001981
Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles. PMID:33001180
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis. PMID:33000262
Uncovering potential differentially expressed miRNAs and targeted mRNAs in myocardial infarction based on integrating analysis. PMID:33000230
Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma. PMID:32999043
SlFERL Interacts with S-Adenosylmethionine Synthetase to Regulate Fruit Ripening. PMID:32999005
Efficient Propagation of Circulating Tumor Cells: A First Step for Probing Tumor Metastasis. PMID:32998338
Identification of the significant pathways of Banxia Houpu decoction in the treatment of depression based on network pharmacology. PMID:32997725
IL6-mediated HCoV-host interactome regulatory network and GO/Pathway enrichment analysis. PMID:32997660
Transcriptomic Analysis Reveals Common Adaptation Mechanisms Under Different Stresses for Moderately Piezophilic Bacteria. PMID:32995929
Immune response and endocytosis pathways are associated with the resilience against Alzheimer's disease. PMID:32994401
Aberration of the modulatory functions of intronic microRNA hsa-miR-933 on its host gene ATF2 results in type II diabetes mellitus and neurodegenerative disease development. PMID:32993798
Transcriptome analysis reveals underlying immune response mechanism of fungal (Penicillium oxalicum) disease in Gastrodia elata Bl. f. glauca S. chow (Orchidaceae). PMID:32993485
Inducible Deletion of YAP and TAZ in Adult Mouse Smooth Muscle Causes Rapid and Lethal Colonic Pseudo-Obstruction. PMID:32992050
Functional signatures of evolutionarily young CTCF binding sites. PMID:32988407
The ModelSEED Biochemistry Database for the integration of metabolic annotations and the reconstruction, comparison and analysis of metabolic models for plants, fungi and microbes. PMID:32986834
Expanded Chinese hamster organ and cell line proteomics profiling reveals tissue-specific functionalities. PMID:32985598
Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells. PMID:32984808
Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes. PMID:32984333
Complement C7 (C7), a Potential Tumor Suppressor, Is an Immune-Related Prognostic Biomarker in Prostate Cancer (PC). PMID:32984006
Therapeutic mechanism of Toujie Quwen granules in COVID-19 based on network pharmacology. PMID:32983259
Identification of Hub Genes and Key Pathways Associated with Peripheral T-cell Lymphoma. PMID:32980897
pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model. PMID:32978366
Genetic background dependent modifiers of craniosynostosis severity. PMID:32976998
TREND-DB-a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation. PMID:32976578
Molecular Characterization of the Coproduced Extracellular Vesicles in HEK293 during Virus-Like Particle Production. PMID:32975947
Analysis of Metabolites and Gene Expression Changes Relative to Apricot (Prunus armeniaca L.) Fruit Quality During Development and Ripening. PMID:32973833
The similarity of inherited diseases (II): clinical and biological similarity between the phenotypic series. PMID:32972400
Burden of rare deleterious variants in WNT signaling genes among 511 myelomeningocele patients. PMID:32970752
Aldh inhibitor restores auditory function in a mouse model of human deafness. PMID:32970669
Tobacco smoking induces metabolic reprogramming of renal cell carcinoma. PMID:32970633
An immune-related gene signature for determining Ewing sarcoma prognosis based on machine learning. PMID:32968877
Gaussian Embedding for Large-scale Gene Set Analysis. PMID:32968711
Genome-wide identification and expression analysis of bZIP gene family in Carthamus tinctorius L. PMID:32968100
Unveiling Sex-Based Differences in the Effects of Alcohol Abuse: A Comprehensive Functional Meta-Analysis of Transcriptomic Studies. PMID:32967293
Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning. PMID:32967266
Identifying Risk Genes and Interpreting Pathogenesis for Parkinson's Disease by a Multiomics Analysis. PMID:32967142
Development of an Intervention Setting Ontology for behaviour change: Specifying where interventions take place. PMID:32964137
Systematic Elucidation of the Mechanism of Quercetin against Gastric Cancer via Network Pharmacology Approach. PMID:32964029
Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing. PMID:32962098
Identification of hub genes in colon cancer via bioinformatics analysis. PMID:32961078
Identification of Significant Genes and Pathways in Acute Pancreatitis via Bioinformatical Analysis. PMID:32960383
Localized inhibition in the Drosophila mushroom body. PMID:32955437
Identification of hub genes in diabetic kidney disease via multiple-microarray analysis. PMID:32953797
Network based analysis of microarray gene expression profiles in response to electroacupuncture. PMID:32953563
Designing custom CRISPR libraries for hypothesis-driven drug target discovery. PMID:32952937
Network pharmacology analysis of the therapeutic mechanisms of the traditional Chinese herbal formula Lian Hua Qing Wen in Corona virus disease 2019 (COVID-19), gives fundamental support to the clinical use of LHQW. PMID:32949888
An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency. PMID:32948837
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells. PMID:32948765
Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes. PMID:32948690
Bioinformatics Data Mining Repurposes the JAK2 (Janus Kinase 2) Inhibitor Fedratinib for Treating Pancreatic Ductal Adenocarcinoma by Reversing the KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog)-Driven Gene Signature. PMID:32947833
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development. PMID:32946788
Transcriptomics predicts compound synergy in drug and natural product treated glioblastoma cells. PMID:32946518
miR‑592 acts as an oncogene and promotes medullary thyroid cancer tumorigenesis by targeting cyclin‑dependent kinase 8. PMID:32945439
Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation. PMID:32945383
The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies. PMID:32945258
PAWER: protein array web exploreR. PMID:32942983
Enzyme-Constrained Models and Omics Analysis of Streptomyces coelicolor Reveal Metabolic Changes that Enhance Heterologous Production. PMID:32942174
Rps27a might act as a controller of microglia activation in triggering neurodegenerative diseases. PMID:32941527
The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation. PMID:32939338
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. PMID:32939051
Revealing the full-length transcriptome of caucasian clover rhizome development. PMID:32938399
Long-read sequencing and de novo genome assembly of marine medaka (Oryzias melastigma). PMID:32938378
Whole-Genome Sequencing Analysis of Quorum Quenching Bacterial Strain Acinetobacter lactucae QL-1 Identifies the FadY Enzyme for Degradation of the Diffusible Signal Factor. PMID:32937869
Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization. PMID:32935492
Identification, Validation, and Functional Annotations of Genome-Wide Profile Variation between Melanocytic Nevus and Malignant Melanoma. PMID:32934956
Cellular expression profiles of Epstein-Barr virus-transformed B-lymphoblastoid cell lines. PMID:32934816
TMEM206 is a potential prognostic marker of hepatocellular carcinoma. PMID:32934741
Immunotyping of tumor-infiltrating lymphocytes in triple-negative breast cancer and genetic characterization. PMID:32934708
The extent of cyclin C promoter occupancy directs changes in stress-dependent transcription. PMID:32934007
Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses. PMID:32929263
Drosophila Voltage-Gated Sodium Channels Are Only Expressed in Active Neurons and Are Localized to Distal Axonal Initial Segment-like Domains. PMID:32928889
A Pilot Study on MicroRNA Profile in Tear Fluid to Predict Response to Anti-VEGF Treatments for Diabetic Macular Edema. PMID:32927780
A Systematic Pharmacology and In Vitro Study to Identify the Role of the Active Compounds of Achyranthes bidentata in the Treatment of Osteoarthritis. PMID:32925869
Using bioinformatics and metabolomics to identify altered granulosa cells in patients with diminished ovarian reserve. PMID:32923184
Identification of tumor-infiltrating immune cells and prognostic validation of tumor-infiltrating mast cells in adrenocortical carcinoma: results from bioinformatics and real-world data. PMID:32923148
The Phoebe genome sheds light on the evolution of magnoliids. PMID:32922818
Expression Profiles of Long Non-coding RNA and Messenger RNA in Human Traumatic Brain Injury. PMID:32919233
Functional Identification of the Dextransucrase Gene of Leuconostoc mesenteroides DRP105. PMID:32916950
Incorporating prior knowledge into regularized regression. PMID:32915960
Single-molecule real-time sequencing of the full-length transcriptome of loquat under low-temperature stress. PMID:32915882
Identification and validation of novel metastasis-related signatures of clear cell renal cell carcinoma using gene expression databases. PMID:32913492
Transcriptional analysis of cleft palate in TGFβ3 mutant mice. PMID:32913205
Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children. PMID:32909006
Identification of Biomarkers to Construct a Competing Endogenous RNA Network and Establishment of a Genomic-Clinicopathologic Nomogram to Predict Survival for Children with Rhabdoid Tumors of the Kidney. PMID:32908900
Bioinformatics Analysis of Key Genes and circRNA-miRNA-mRNA Regulatory Network in Gastric Cancer. PMID:32908877
Analysis of Differentially Expressed Genes in Necrotic Enteritis-infected Fayoumi Chickens using RNA Sequencing. PMID:32908417
A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade. PMID:32907939
Finding semantic patterns in omics data using concept rule learning with an ontology-based refinement operator. PMID:32905086
Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival. PMID:32904984
Identification of Immune-Related Prognostic Biomarkers Based on the Tumor Microenvironment in 20 Malignant Tumor Types With Poor Prognosis. PMID:32903590
RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk. PMID:32901120
Conserved Patterns in Developmental Processes and Phases, Rather than Genes, Unite the Highly Divergent Bilateria. PMID:32899936
In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age. PMID:32898168
Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells. PMID:32897294
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission. PMID:32895383
Identification of a metabolism-related gene expression prognostic model in endometrial carcinoma patients. PMID:32894095
Functional, Morphological, and Evolutionary Characterization of Hearing in Subterranean, Eusocial African Mole-Rats. PMID:32888484
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver. PMID:32888418
Environmental stability impacts the differential sensitivity of marine microbiomes to increases in temperature and acidity. PMID:32887943
Telomere-to-telomere assembled and centromere annotated genomes of the two main subspecies of the button mushroom Agaricus bisporus reveal especially polymorphic chromosome ends. PMID:32887908
Active Packaging of Immobilized Zinc Oxide Nanoparticles Controls Campylobacter jejuni in Raw Chicken Meat. PMID:32887715
De novo transcriptome sequencing of Rhododendron molle and identification of genes involved in the biosynthesis of secondary metabolites. PMID:32887550
Single-Cell NGS-Based Analysis of Copy Number Alterations Reveals New Insights in Circulating Tumor Cells Persistence in Early-Stage Breast Cancer. PMID:32887501
Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics. PMID:32886718
Identification of circular RNA hsa_circ_0044556 and its effect on the progression of colorectal cancer. PMID:32884449
Complete Genome Sequence of Pseudomonas aeruginosa XN-1, Isolated from the Sputum of a Severe Pneumonia Patient. PMID:32883796
De novo transcriptome assembly and population genetic analyses of an important coastal shrub, Apocynum venetum L. PMID:32883231
Pathogenic impact of transcript isoform switching in 1,209 cancer samples covering 27 cancer types using an isoform-specific interaction network. PMID:32879328
Secretome Proteomic Approaches for Biomarker Discovery: An Update on Colorectal Cancer.