UCSC Genome Browser database
Names
More detailed information about this field from each metasource.
UCSC Genome Browser database
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
UCSC Genome Browser
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
UCSC Genome Bioinformatics
metasource: re3data.org
version: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
University of California Santa Cruz Genome Bioinformatics
metasource: re3data.org
version: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
ucsc_genome_browser
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
Names
More detailed information about this field from each metasource.
UCSC Genome Browser database
metasource: Fairsharing.orgversion: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
UCSC Genome Browser
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
UCSC Genome Bioinformatics
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
University of California Santa Cruz Genome Bioinformatics
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
ucsc_genome_browser
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:08.071742
Other names: UCSC Genome Browser, UCSC Genome Bioinformatics, University of California Santa Cruz Genome Bioinformatics, ucsc_genome_browser
Names
More detailed information about this field from each metasource.
UCSC Genome Browser database
metasource: Fairsharing.orgversion: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
UCSC Genome Browser
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
UCSC Genome Bioinformatics
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
University of California Santa Cruz Genome Bioinformatics
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
ucsc_genome_browser
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:08.071742
Genome assemblies and aligned annotations for a wide range of vertebrates and model organisms, along with an integrated tool set for visualizing, comparing, analyzing and sharing both publicly available and user-generated genomic datasets.
Description
More detailed information about this field from each metasource.
Genome assemblies and aligned annotations for a wide range of vertebrates and model organisms, along with an integrated tool set for visualizing, comparing, analyzing and sharing both publicly available and user-generated genomic datasets.
metasource: Fairsharing.orgversion: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The University of California Santa Cruz (UCSC) Genome Browser (http://genome.ucsc.edu) offers online public access to a growing database of genomic sequence and annotations for a large collection of organisms, primarily vertebrates, with an emphasis on the human and mouse genomes. The Browser’s Web-based tools – including BLAT, the Table Browser, VisiGene, the Gene Sorter, Genome Graphs, and the Variant Annotation Integrator -- provide an integrated environment for visualizing, comparing, analyzing, and sharing both publicly available and user-generated genomic data sets. As of September 2016, the database contained genomic sequence and a basic set of annotation ‘tracks’ for 96 unique species, many with multiple assembly versions. Most genome assemblies offer mapping and sequence annotation tracks describing assembly, gap, and GC content, and alignments of mRNA, EST, and RefSeq data from GenBank. Some assemblies provide additional gene annotations and sequence alignments of selected species to facilitate comparative and evolutionary investigations. The heavily annotated human genome offers extensive conservation and evolutionary comparisons, a large collection of gene models, regulation, expression, epigenetics and tissue differentiation, variation, phenotype and disease association data, and text-mined data from publications. In addition to the native data sets local to the UCSC servers, the Genome Browser offers several options to users for viewing their own sequence and annotations: track and assembly data hubs, custom tracks, and sessions. The Genome Browser database and tools may also be installed on a local server for customized use. The full set of data, software tools, downloads, and documentation can be found on the Genome Browser website.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations. The Browser is a graphical viewer optimized to support fast interactive performance and is an open-source, web-based tool suite built on top of a MySQL database for rapid visualization, examination, and querying of the data at many levels.
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
Large database of publicly available sequence and annotation data along with an integrated tool set for examining and comparing the genomes of organisms, aligning sequence to genomes, and displaying and sharing users own annotation data.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:08.071742
Webpage:
http://genome.ucsc.eduWebpage
More detailed information about this field from each metasource.
http://genome.ucsc.edu
metasource: Fairsharing.orgversion: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
http://genome.ucsc.edu/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
https://genome.ucsc.edu/
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
Licence:
Name: otherLicence name
More detailed information about this field from each metasource.
other
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
Apache-2.0
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:08.071742
Licence URL
More detailed information about this field from each metasource.
https://genome.ucsc.edu/license/gblicense.pdf
metasource: re3data.orgversion: re3data.org: UCSC Genome Browser; editing status 2021-08-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3RK5C last accessed: 2022-11-04
Publications:
(29)
Publications
More detailed information about this field from each metasource.
Initial sequencing and analysis of the human genome
PMID: 11237011
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The human genome browser at UCSC
PMID: 12045153
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
BLAT--the BLAST-like alignment tool
PMID: 11932250
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Table Browser data retrieval tool
PMID: 14681465
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser Database
PMID: 12519945
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: update 2011
PMID: 20959295
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser Database: update 2006
PMID: 16381938
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2015 update
PMID: 25428374
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: extensions and updates 2013
PMID: 23155063
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
ENCODE data in the UCSC Genome Browser: year 5 update
PMID: 23193274
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser database: 2014 update
PMID: 24270787
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: update 2010
PMID: 19906737
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2019 update
PMID: 30407534
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser Database: 2008 update
PMID: 18086701
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2018 update
PMID: 29106570
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser Database: update 2009
PMID: 18996895
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2016 update
PMID: 26590259
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: extensions and updates 2011
PMID: 22086951
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2017 update
PMID: 27899642
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
ENCODE whole-genome data in the UCSC Genome Browser: update 2012
PMID: 22075998
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2021 update
PMID: 33221922
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
UCSC Genome Browser enters 20th year
PMID: 31691824
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Assembly of the working draft of the human genome with GigAssembler
PMID: 11544197
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC SARS-CoV-2 Genome Browser
PMID: 32908258
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser
PMID: 23255150
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Exploring relationships and mining data with the UCSC Gene Sorter
PMID: 15867434
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC repeat browser allows discovery and visualization of evolutionary conflict across repeat families
PMID: 32266012
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Ultrafast Sample Placement on Existing Trees (UShER) Empowers Real-Time Phylogenetics for the SARS-CoV-2 Pandemic
PMID: 33024970
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
http://dx.doi.org/10.1093/nar/gkv1275
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
Initial sequencing and analysis of the human genome
PMID: 11237011
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The human genome browser at UCSC
PMID: 12045153
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
BLAT--the BLAST-like alignment tool
PMID: 11932250
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Table Browser data retrieval tool
PMID: 14681465
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser Database
PMID: 12519945
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: update 2011
PMID: 20959295
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser Database: update 2006
PMID: 16381938
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2015 update
PMID: 25428374
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: extensions and updates 2013
PMID: 23155063
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
ENCODE data in the UCSC Genome Browser: year 5 update
PMID: 23193274
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser database: 2014 update
PMID: 24270787
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: update 2010
PMID: 19906737
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2019 update
PMID: 30407534
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser Database: 2008 update
PMID: 18086701
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2018 update
PMID: 29106570
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser Database: update 2009
PMID: 18996895
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2016 update
PMID: 26590259
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: extensions and updates 2011
PMID: 22086951
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2017 update
PMID: 27899642
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
ENCODE whole-genome data in the UCSC Genome Browser: update 2012
PMID: 22075998
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.071742
The UCSC Genome Browser database: 2021 update
PMID: 33221922
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
UCSC Genome Browser enters 20th year
PMID: 31691824
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Assembly of the working draft of the human genome with GigAssembler
PMID: 11544197
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC SARS-CoV-2 Genome Browser
PMID: 32908258
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC Genome Browser
PMID: 23255150
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Exploring relationships and mining data with the UCSC Gene Sorter
PMID: 15867434
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The UCSC repeat browser allows discovery and visualization of evolutionary conflict across repeat families
PMID: 32266012
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Ultrafast Sample Placement on Existing Trees (UShER) Empowers Real-Time Phylogenetics for the SARS-CoV-2 Pandemic
PMID: 33024970
metasource: Fairsharing.org
version: FAIRsharing.org: UCSC Genome Browser database; UCSC Genome Browser database; DOI: https://doi.org/10.25504/FAIRsharing.s22qdj; Last edited: June 30, 2021, 8:33 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
http://dx.doi.org/10.1093/nar/gkv1275
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
-
Initial sequencing and analysis of the human genome
PubMed citations: 7134.
7134 articles citing: Initial sequencing and analysis of the human genome
Four novel candidate causal variants for deficient homozygous haplotypes in Holstein cattle. PMID:35361830
Variability in Global DNA Methylation Rate Across Tissues and Over Time in Sheep. PMID:35360841
Significant Upregulation of HERV-K (HML-2) Transcription Levels in Human Lung Cancer and Cancer Cells. PMID:35359739
A beginner's guide to manual curation of transposable elements. PMID:35354491
Rethinking Protein Drug Design with Highly Accurate Structure Prediction of Anti-CRISPR Proteins. PMID:35337108
In Vitro Analysis of Biological Activity of Circulating Cell-Free DNA Isolated from Blood Plasma of Schizophrenic Patients and Healthy Controls. PMID:35328103
An Expanding Toolkit for Heterochromatin Repair Studies. PMID:35328082
IMGT®Homo sapiens IG and TR Loci, Gene Order, CNV and Haplotypes: New Concepts as a Paradigm for Jawed Vertebrates Genome Assemblies. PMID:35327572
Transposable Elements: Major Players in Shaping Genomic and Evolutionary Patterns. PMID:35326499
TrkB Truncated Isoform Receptors as Transducers and Determinants of BDNF Functions. PMID:35321093
Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells. PMID:35315771
Teaching cancer imaging in the era of precision medicine: Looking at the big picture. PMID:35309874
The 103,200-arm acceleration dataset in the UK Biobank revealed a landscape of human sleep phenotypes. PMID:35302893
Short open reading frames (sORFs) and microproteins: an update on their identification and validation measures. PMID:35300685
FDA-led consortium studies advance quality control of targeted next generation sequencing assays for precision oncology. PMID:35282311
MER4 endogenous retrovirus correlated with better efficacy of anti-PD1/PD-L1 therapy in non-small cell lung cancer. PMID:35277462
Principles for the design of multicellular engineered living systems. PMID:35274072
Indicators of Successful Career Transitions from Physical Sciences and Engineering to Biomedical Research. PMID:35273460
Inter-Species Rescue of Mutant Phenotype-The Standard for Genetic Analysis of Human Genetic Disorders in Drosophila melanogaster Model. PMID:35269756
Transposable Elements and Human Diseases: Mechanisms and Implication in the Response to Environmental Pollutants. PMID:35269693
Constitutive Heterochromatin in Eukaryotic Genomes: A Mine of Transposable Elements. PMID:35269383
ALU repeat as potential molecular marker in the detection and prognosis of different cancer types: A systematic review. PMID:35251637
A novel concept of human antiviral protection: It's all about RNA (Review). PMID:35251616
Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells. PMID:35243263
Transposable element landscapes in aging Drosophila. PMID:35239675
VPipe: an Automated Bioinformatics Platform for Assembly and Management of Viral Next-Generation Sequencing Data. PMID:35234489
Roles of transposable elements in the regulation of mammalian transcription. PMID:35228718
A guide for the diagnosis of rare and undiagnosed disease: beyond the exome. PMID:35220969
The Complexity of the Mammalian Transcriptome. PMID:35220563
Expanding Gene-Editing Potential in Crop Improvement with Pangenomes. PMID:35216392
Characterizing mobile element insertions in 5675 genomes. PMID:35212372
Low Expression of ZNF154 is Related to Poor Prognosis in Gastric Cancer. PMID:35210862
Insights into the Association Between QSER1 and M2 Macrophages and Remarkable Malignancy Characteristics in Hepatocellular Carcinoma. PMID:35210841
To Be or Not to Be Mesophilic, That Is the Question for Aeromonas salmonicida. PMID:35208695
The Ribosomal Protein RpL22 Interacts In Vitro with 5'-UTR Sequences Found in Some Drosophila melanogaster Transposons. PMID:35205350
Splicing Variants, Protein-Protein Interactions, and Drug Targeting in Hutchinson-Gilford Progeria Syndrome and Small Cell Lung Cancer. PMID:35205210
Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method. PMID:35203259
Cryo-EM advances in RNA structure determination. PMID:35197441
[Web-based gene expression analysis-paving the way to decode healthy and diseased ocular tissue]. PMID:35194679
Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations. PMID:35193936
An Alu insertion map of the Indian population: identification and analysis in 1021 genomes of the IndiGen project. PMID:35178516
Particulate matter-induced hypomethylation of Alu and LINE1 in normal human bronchial epithelial cells and epidermal keratinocytes. PMID:35172897
MxB inhibits long interspersed element type 1 retrotransposition. PMID:35171907
Machine learning for multi-omics data integration in cancer. PMID:35169688
The Absence of Retroelement Activity Is Characteristic for Childhood Acute Leukemias and Adult Acute Lymphoblastic Leukemia. PMID:35163677
A Systematic Review of Expression and Immunogenicity of Human Endogenous Retroviral Proteins in Cancer and Discussion of Therapeutic Approaches. PMID:35163254
Polycystic Ovary Syndrome: An Evolutionary Adaptation to Lifestyle and the Environment. PMID:35162359
Disparities in Lung Cancer: miRNA Isoform Characterization in Lung Adenocarcinoma. PMID:35159038
Bitter taste receptors: Genes, evolution and health. PMID:35154779
Genetic variation of pharmacogenomic VIP variants in the Chinese Li population: an updated research. PMID:35146537
Emerging roles of circular RNAs in retinal diseases. PMID:35142661
Analysis of Pathogenic Pseudoexons Reveals Novel Mechanisms Driving Cryptic Splicing. PMID:35140743
Functional Precision Medicine: Putting Drugs on Patient Cancer Cells and Seeing What Happens. PMID:35140175
The mouse resource at National Resource Center for Mutant Mice. PMID:35138443
WAFNRLTG: A Novel Model for Predicting LncRNA Target Genes Based on Weighted Average Fusion Network Representation Learning Method. PMID:35127729
Translational Informatics for Natural Products as Antidepressant Agents. PMID:35127696
Mouse genomic and cellular annotations. PMID:35124726
Exposome and Skin: Part 1. Bibliometric Analysis and Review of the Impact of Exposome Approaches on Dermatology. PMID:35112325
Highly sensitive diagnostic method for colorectal cancer using the ratio of free DNA fragments in serum. PMID:35111495
ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8+ T Cell Effector and Memory Responses. PMID:35110421
Genomic deciphering of sex determination and unique immune system of a potential model species rare minnow (Gobiocypris rarus). PMID:35108042
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study. PMID:35106505
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice. PMID:35103851
Long Noncoding RNA Mediated Regulation in Human Embryogenesis, Pluripotency, and Reproduction. PMID:35103065
Context dependency of nucleotide probabilities and variants in human DNA. PMID:35100973
Analysis of epigenetic features characteristic of L1 loci expressed in human cells. PMID:35100410
Caenorhabditis elegans transposable elements harbor diverse transcription factor DNA-binding sites. PMID:35088854
Shaping the Innate Immune Response Through Post-Transcriptional Regulation of Gene Expression Mediated by RNA-Binding Proteins. PMID:35087521
Exploring clinical implications and role of non-coding RNAs in lung carcinogenesis. PMID:35076850
A simple guide to de novo transcriptome assembly and annotation. PMID:35076693
HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk. PMID:35062349
Endogenous Retroviruses Provide Protection Against Vaginal HSV-2 Disease. PMID:35058919
Third-Generation Sequencing: The Spearhead towards the Radical Transformation of Modern Genomics. PMID:35054423
Molecular Mechanisms in Pentanucleotide Repeat Diseases. PMID:35053321
Recent Advances in RNA Therapy and Its Carriers to Treat the Single-Gene Neurological Disorders. PMID:35052837
Genome-wide perturbations of Alu expression and Alu-associated post-transcriptional regulations distinguish oligodendroglioma from other gliomas. PMID:35042936
Balancing openness with Indigenous data sovereignty: An opportunity to leave no one behind in the journey to sequence all of life. PMID:35042810
Darwinian genomics and diversity in the tree of life. PMID:35042807
Threatened Species Initiative: Empowering conservation action using genomic resources. PMID:35042806
Standards recommendations for the Earth BioGenome Project. PMID:35042802
Why sequence all eukaryotes? PMID:35042801
LINE1 are spliced in non-canonical transcript variants to regulate T cell quiescence and exhaustion. PMID:35039641
Core promoter mutation contributes to abnormal gene expression in bladder cancer. PMID:35033028
GC content of plant genes is linked to past gene duplications. PMID:35025913
Identification of human gene research articles with wrongly identified nucleotide sequences. PMID:35022248
Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome. PMID:35022065
Automated prediction of the clinical impact of structural copy number variations. PMID:35017614
Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site. PMID:35017527
Mechanism for inverted-repeat recombination induced by a replication fork barrier. PMID:35013185
PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner. PMID:35013001
Population-level genome-wide STR discovery and validation for population structure and genetic diversity assessment of Plasmodium species. PMID:35007277
The evolution of knowledge on genes associated with human diseases. PMID:35005554
Cohort Profile: The Alliance for Maternal and Newborn Health Improvement (AMANHI) biobanking study. PMID:34999881
The characteristics of early-stage research into human genes are substantially different from subsequent research. PMID:34990452
Cure and Long-Term Remission Strategies. PMID:34985678
Assessing reproducibility of inherited variants detected with short-read whole genome sequencing. PMID:34980216
Firing up Cold Tumors-Targeting the Epigenetic Machinery to Enhance Cancer Immunotherapy. PMID:34968298
Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology. PMID:34968293
EZH2 suppresses endogenous retroviruses and an interferon response in cancers. PMID:34966479
Structure, Activity, and Function of SETMAR Protein Lysine Methyltransferase. PMID:34947873
Chromatography-Free Purification Strategies for Large Biological Macromolecular Complexes Involving Fractionated PEG Precipitation and Density Gradients. PMID:34947821
Endogenous Retroviral Elements in Human Development and Central Nervous System Embryonal Tumors. PMID:34945804
Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry. PMID:34944967
Methylation Markers in Cutaneous Melanoma: Unravelling the Potential Utility of Their Tracking by Liquid Biopsy. PMID:34944843
Reverse Genetic Screen for Deleterious Recessive Variants in the Local Simmental Cattle Population of Switzerland. PMID:34944310
Transgenic Model Systems Have Revolutionized the Study of Disease. PMID:34941457
Long-range promoter-enhancer contacts are conserved during evolution and contribute to gene expression robustness. PMID:34930799
Molecular Diagnostics for Ocular Infectious Diseases: LXXVIII Edward Jackson Memorial Lecture. PMID:34921773
Human endogenous retroviruses (HERV) and non-HERV viruses incorporated into the human genome and their role in the development of autoimmune diseases. PMID:34917914
Mining massive genomic data of two Swiss Braunvieh cattle populations reveals six novel candidate variants that impair reproductive success. PMID:34915862
Gauging the role and impact of drug interactions and repurposing in neurodegenerative disorders. PMID:34909657
The Vista of Application of Specific Anaphylaxis Accurate Diagnosis Based on DNA Single-Nucleotide Methylation Sites. PMID:34908915
Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era. PMID:34901902
A Method for Localizing Non-Reference Sequences to the Human Genome. PMID:34890159
Targeted insertion of large genetic payloads using cas directed LINE-1 reverse transcriptase. PMID:34880381
Transcription factor network analysis based on single cell RNA-seq identifies that Trichostatin-a reverses docetaxel resistance in prostate Cancer. PMID:34879849
DNA Profiling in Forensic Science: A Review. PMID:34877570
Human endogenous retroviruses in development and disease. PMID:34849202
Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients. PMID:34848679
Advances in Non-Coding RNA Sequencing. PMID:34842804
DNA sequencing: an overview of solid-state and biological nanopore-based methods. PMID:34840616
From genotype to phenotype: genetics of mammalian long non-coding RNAs in vivo. PMID:34837040
Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia. PMID:34836750
Stochastic Effects in Retrotransposon Dynamics Revealed by Modeling under Competition for Cellular Resources. PMID:34833085
Diversity-Oriented Synthesis: Amino Acetophenones as Building Blocks for the Synthesis of Natural Product Analogs. PMID:34832909
The Evolutionary Volte-Face of Transposable Elements: From Harmful Jumping Genes to Major Drivers of Genetic Innovation. PMID:34831175
Evidence of G-Protein-Coupled Receptors (GPCR) in the Parasitic Protozoa Plasmodium falciparum-Sensing the Host Environment and Coupling within Its Molecular Signaling Toolkit. PMID:34830263
Role of Non-Coding RNAs in Post-Transcriptional Regulation of Lung Diseases. PMID:34819948
Emerging roles for endogenous retroviruses in immune epigenetic regulation. PMID:34816452
Bringing precision oncology to cellular resolution with single-cell genomics. PMID:34807338
Alu insertion variants alter gene transcript levels. PMID:34799402
Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation. PMID:34791430
Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis. PMID:34790199
Characterization of DNA methylation and promoter activity of long terminal repeat elements of feline endogenous retrovirus RDRS C2a. PMID:34787790
Locus-specific expression of transposable elements in single cells with CELLO-seq. PMID:34782740
Adaptive homeostasis and the p53 isoform network. PMID:34779563
Targeting Phosphatases and Kinases: How to Checkmate Cancer. PMID:34778245
Accurate long-read de novo assembly evaluation with Inspector. PMID:34775997
Mutagenesis of human genomes by endogenous mobile elements on a population scale. PMID:34772701
Histone Modification in NSCLC: Molecular Mechanisms and Therapeutic Targets. PMID:34769131
Recent development of nucleic acid nanosensors to detect sequence-specific binding interactions: From metal ions, small molecules to proteins and pathogens. PMID:34766041
AI applications in functional genomics. PMID:34765093
Computational modeling of RNase, antisense ORF0 RNA, and intracellular compartmentation and their impact on the life cycle of the line retrotransposon. PMID:34765087
Perfect and imperfect views of ultraconserved sequences. PMID:34764456
tsRFun: a comprehensive platform for decoding human tsRNA expression, functions and prognostic value by high-throughput small RNA-Seq and CLIP-Seq data. PMID:34755848
Roles and mechanisms of exosomal non-coding RNAs in human health and diseases. PMID:34753929
The transposable element-rich genome of the cereal pest Sitophilus oryzae. PMID:34749730
Post-transcriptional regulation in spermatogenesis: all RNA pathways lead to healthy sperm. PMID:34748024
The Genomic Organization of the LILR Region Remained Largely Conserved Throughout Primate Evolution: Implications for Health And Disease. PMID:34737739
Non-Coding RNAs in the Etiology and Control of Major and Neglected Human Tropical Diseases. PMID:34737736
'Omics' of suicidal behaviour: A path to personalised psychiatry. PMID:34733641
BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5' UTR. PMID:34730388
An integrative analysis of genomic and exposomic data for complex traits and phenotypic prediction. PMID:34728654
An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity. PMID:34727520
Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci. PMID:34699533
Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing. PMID:34694871
Transposable Element Dynamics and Regulation during Zygotic Genome Activation in Mammalian Embryos and Embryonic Stem Cell Model Systems. PMID:34691189
Genetic Regulation of Immunoglobulin G Glycosylation. PMID:34687013
Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications. PMID:34681626
Implications of Antigen Selection on T Cell-Based Immunotherapy. PMID:34681217
Factors Regulating the Activity of LINE1 Retrotransposons. PMID:34680956
The Quest for Genes Involved in Adaptation to Climate Change in Ruminant Livestock. PMID:34679854
Embryonic LTR retrotransposons supply promoter modules to somatic tissues. PMID:34675070
Alu RNA and their roles in human disease states. PMID:34672903
Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system. PMID:34670118
Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation. PMID:34656143
MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells. PMID:34650118
Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase. PMID:34649994
Complex Transposon Insertion as a Novel Cause of Pompe Disease. PMID:34639227
Phospho-Tau and Chromatin Landscapes in Early and Late Alzheimer's Disease. PMID:34638632
Emerging Functions for snoRNAs and snoRNA-Derived Fragments. PMID:34638533
RNA Therapeutics - Research and Clinical Advancements. PMID:34631795
Genome-wide analysis of DNA methylation in 106 schizophrenia family trios in Han Chinese. PMID:34628353
Telomere-specific chromatin capture using a pyrrole-imidazole polyamide probe for the identification of proteins and non-coding RNAs. PMID:34627342
High-quality reference genome of Fasciola gigantica: Insights into the genomic signatures of transposon-mediated evolution and specific parasitic adaption in tropical regions. PMID:34610021
Regulated splicing of large exons is linked to phase-separation of vertebrate transcription factors. PMID:34605568
Easy and fast PCR-based protocol allows characterization of breakpoints resulting from Alu/Alu-mediated genomic rearrangements. PMID:34596355
Evolutionary genetics and acclimatization in nephrology. PMID:34584272
Androgen-Binding Protein (Abp) Evolutionary History: Has Positive Selection Caused Fixation of Different Paralogs in Different Taxa of the Genus Mus? PMID:34581786
Does the Zinc Finger Antiviral Protein (ZAP) Shape the Evolution of Herpesvirus Genomes? PMID:34578438
Identification of Abundant and Functional dodecaRNAs (doRNAs) Derived from Ribosomal RNA. PMID:34575920
The Sound of Silence: How Silenced Chromatin Orchestrates the Repair of Double-Strand Breaks. PMID:34573397
Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19. PMID:34572502
Phosphorylation-Mediated Molecular Pathway Changes in Human Pituitary Neuroendocrine Tumors Identified by Quantitative Phosphoproteomics. PMID:34571875
Bioinformatics and Machine Learning Approaches to Understand the Regulation of Mobile Genetic Elements. PMID:34571773
A broad analysis of splicing regulation in yeast using a large library of synthetic introns. PMID:34570750
Detection of Alu Exonization Events in Human Frontal Cortex From RNA-Seq Data. PMID:34568430
Editorial: Pathogens, Pathobionts, and Autoimmunity. PMID:34567014
The Interplay Among HIV, LINE-1, and the Interferon Signaling System. PMID:34566998
Sex, rurality and socioeconomical status in Spanish centennial population (2017). PMID:34565717
Proteomes Are of Proteoforms: Embracing the Complexity. PMID:34564541
Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. PMID:34556881
Pharmaceutical drug development: high drug prices and the hidden role of public funding. PMID:34554467
The function of twister ribozyme variants in non-LTR retrotransposition in Schistosoma mansoni. PMID:34551436
Data Management and Modeling in Plant Biology. PMID:34539712
Characterization of full-length LINE-1 insertions in 154 genomes. PMID:34534648
International strategy in cancer epidemiology: Japan's involvement in global projects and future role. PMID:34532599
DNA double-strand break repair in cancer: A path to achieving precision medicine. PMID:34507781
Possible Roles of tRNA Fragments, as New Regulatory ncRNAs, in the Pathogenesis of Rheumatoid Arthritis. PMID:34502386
Proximity labeling and other novel mass spectrometric approaches for spatiotemporal protein dynamics. PMID:34496693
Endogenous Feline Leukemia Virus (FeLV) siRNA Transcription May Interfere with Exogenous FeLV Infection. PMID:34495702
A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci. PMID:34489471
Psi-Caller: A Lightweight Short Read-Based Variant Caller With High Speed and Accuracy. PMID:34485311
Systematic Comparison of the Performances of De Novo Genome Assemblers for Oxford Nanopore Technology Reads From Piroplasm. PMID:34485177
Shared properties and singularities of exoribonuclease-resistant RNAs in viruses. PMID:34471487
Alpha Satellite Insertion Close to an Ancestral Centromeric Region. PMID:34464971
The Propagation of Racial Disparities in Cardiovascular Genomics Research. PMID:34461749
DNA methyltransferase inhibitors combination therapy for the treatment of solid tumor: mechanism and clinical application. PMID:34452630
Advances in Computational Methodologies for Classification and Sub-Cellular Locality Prediction of Non-Coding RNAs. PMID:34445436
The Role of lncRNA in the Development of Tumors, including Breast Cancer. PMID:34445129
Suggested Absence of Horizontal Transfer of Retrotransposons between Humans and Domestic Mammal Species. PMID:34440397
Transposons-Based Clonal Diversity in Trematode Involves Parts of CR1 (LINE) in Eu- and Heterochromatin. PMID:34440303
The Key Lnc (RNA)s in Cardiac and Skeletal Muscle Development, Regeneration, and Disease. PMID:34436226
An Ancestral Retrovirus Envelope Protein Regulates Persistent Gammaherpesvirus Lifecycles. PMID:34434177
Cohort Profile: The Alliance for Maternal and Newborn Health Improvement (AMANHI) biobanking study. PMID:34426827
Unbiased proteomic mapping of the LINE-1 promoter using CRISPR Cas9. PMID:34425899
Study of lncRNA TPA in Promoting Invasion and Metastasis of Breast Cancer Mediated by TGF-β Signaling Pathway. PMID:34422811
Appropriate Clinical Genetic Testing of Hemochromatosis Type 2-4, Including Ferroportin Disease. PMID:34413666
One-carbon metabolism and global DNA methylation in mothers of individuals with Down syndrome. PMID:34410622
The Oldest Co-opted gag Gene of a Human Endogenous Retrovirus Shows Placenta-Specific Expression and Is Upregulated in Diffuse Large B-Cell Lymphomas. PMID:34410386
A comprehensive analysis of gorilla-specific LINE-1 retrotransposons. PMID:34406591
Segmental duplication as potential biomarkers for non-invasive prenatal testing of aneuploidies. PMID:34391089
A strategy for building and using a human reference pangenome. PMID:34386196
Expression of a human cDNA in moss results in spliced mRNAs and fragmentary protein isoforms. PMID:34385580
DeepG4: A deep learning approach to predict cell-type specific active G-quadruplex regions. PMID:34383754
Exploring tissue architecture using spatial transcriptomics. PMID:34381231
Genome-wide mapping of binding sites of the transposase-derived SETMAR protein in the human genome. PMID:34377368
Viral Suppression of RIPK1-Mediated Signaling. PMID:34372694
JWES: a new pipeline for whole genome/exome sequence data processing, management, and gene-variant discovery, annotation, prediction, and genotyping. PMID:34370400
Application of NGS Technology in Understanding the Pathology of Autoimmune Diseases. PMID:34362117
Signaling Pathways Regulated by UBR Box-Containing E3 Ligases. PMID:34361089
Genomic Mosaicism Formed by Somatic Variation in the Aging and Diseased Brain. PMID:34356087
Transposable elements shape the evolution of mammalian development. PMID:34354263
Raptor: A fast and space-efficient pre-filter for querying very large collections of nucleotide sequences. PMID:34337360
Current diagnostic approaches to detect two important betacoronaviruses: Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). PMID:34333398
Replication protein A: a multifunctional protein with roles in DNA replication, repair and beyond. PMID:34316690
Haplotypic Associations and Differentiation of MHC Class II Polymorphic Alu Insertions at Five Loci With HLA-DRB1 Alleles in 12 Minority Ethnic Populations in China. PMID:34305999
Role of long interspersed nuclear element-1 in the regulation of chromatin landscapes and genome dynamics. PMID:34304633
Adenosine-to-inosine Alu RNA editing controls the stability of the pro-inflammatory long noncoding RNA NEAT1 in atherosclerotic cardiovascular disease. PMID:34302813
Expanding studies of chromosome structure and function in the era of T2T genomics. PMID:34302168
Activation of Endogenous Retrovirus, Brain Infections and Environmental Insults in Neurodegeneration and Alzheimer's Disease. PMID:34298881
Discovery of genomic variation across a generation. PMID:34296264
New Genes Born-In or Invading Vertebrate Genomes. PMID:34295903
Highly accurate protein structure prediction for the human proteome. PMID:34293799
Perturbed DNA methylation by Gadd45b induces chromatin disorganization, DNA strand breaks and dopaminergic neuron death. PMID:34278264
A pooled CRISPR/AsCpf1 screen using paired gRNAs to induce genomic deletions in Chinese hamster ovary cells. PMID:34277363
Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2. PMID:34276797
Impact of Genetic Variation in Gene Regulatory Sequences: A Population Genomics Perspective. PMID:34276769
Distinct Retrotransposon Evolution Profile in the Genome of Rabbit (Oryctolagus cuniculus). PMID:34270728
The International Human Genome Project. PMID:34264324
Metagenomics: a path to understanding the gut microbiome. PMID:34259891
Levenshtein Distance, Sequence Comparison and Biological Database Search. PMID:34257466
Profiling variable-number tandem repeat variation across populations using repeat-pangenome graphs. PMID:34253730
A direct capture method for purification and detection of viral nucleic acid enables epidemiological surveillance of SARS-CoV-2. PMID:34252764
Markov chain Monte Carlo Gibbs sampler approach for estimating haplotype frequencies among multiple malaria infected human blood samples. PMID:34246273
Global mapping of cancers: The Cancer Genome Atlas and beyond. PMID:34245122
Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes. PMID:34244519
Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer. PMID:34242741
Multiscale modeling of genome organization with maximum entropy optimization. PMID:34241389
Binding patterns of RNA-binding proteins to repeat-derived RNA sequences reveal putative functional RNA elements. PMID:34235430
Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations. PMID:34233005
Cognate restriction of transposition by piggyBac-like proteins. PMID:34232995
The RNA editing enzyme ADAR2 restricts L1 mobility. PMID:34224323
Nanopore Technology and Its Applications in Gene Sequencing. PMID:34208844
The Structural, Functional and Evolutionary Impact of Transposable Elements in Eukaryotes. PMID:34203645
Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome. PMID:34187812
Evolution of mouse circadian enhancers from transposable elements. PMID:34187518
Expression of Retroelements in Mammalian Gametes and Embryos. PMID:34182464
Lack of relationship between Alu repetitive elements in angiotensin converting enzyme and the severity of diabetic retinopathy. PMID:34177375
Man is a "Rope" Stretched Between Virosphere and Humanoid Robots: On the Urgent Need of an Ethical Code for Ecosystem Survival. PMID:34177285
A perspective on the molecular simulation of DNA from structural and functional aspects. PMID:34168783
Debugging: putting the synthetic yeast chromosome to work. PMID:34168782
Genetics of white color and iridophoroma in "Lemon Frost" leopard geckos. PMID:34166378
Genome-wide binding analysis of 195 DNA binding proteins reveals "reservoir" promoters and human specific SVA-repeat family regulation. PMID:34166368
Unraveling Genome Evolution Throughout Visual Analysis: The XCout Portal. PMID:34163150
Haplotype diversity and sequence heterogeneity of human telomeres. PMID:34162698
Viewing Victor McKusick's legacy through the lens of his bibliography. PMID:34159717
History of the methodology of disease gene identification. PMID:34159713
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells. PMID:34158624
Mobile element insertions and associated structural variants in longitudinal breast cancer samples. PMID:34158539
Comprehensive identification of transposable element insertions using multiple sequencing technologies. PMID:34158502
Sequence determinants, function, and evolution of CpG islands. PMID:34156435
Hepatocellular adenoma in men: A nationwide assessment of pathology and correlation with clinical course. PMID:34155783
SMARCB1 deletion in atypical teratoid rhabdoid tumors results in human endogenous retrovirus K (HML-2) expression. PMID:34145313
Molecular mechanisms underlying nucleotide repeat expansion disorders. PMID:34140671
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA. PMID:34140313
Convergent and distributed effects of the 3q29 deletion on the human neural transcriptome. PMID:34131099
Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations. PMID:34128976
Haplotype Shuffling and Dimorphic Transposable Elements in the Human Extended Major Histocompatibility Complex Class II Region. PMID:34122517
UMIc: A Preprocessing Method for UMI Deduplication and Reads Correction. PMID:34122513
Cas9 targeted enrichment of mobile elements using nanopore sequencing. PMID:34117247
Interphase Chromosomes in Replicative Senescence: Chromosome Positioning as a Senescence Biomarker and the Lack of Nuclear Motor-Driven Chromosome Repositioning in Senescent Cells. PMID:34113611
Specialty Grand Challenge for Molecular Signalling and Pathways in Molecular Neuroscience. PMID:34108865
RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability. PMID:34108665
The pseudogene PRELID1P6 promotes glioma progression via the hnHNPH1-Akt/mTOR axis. PMID:34108621
The derepression of transposable elements in lung cells is associated with the inflammatory response and gene activation in idiopathic pulmonary fibrosis. PMID:34108012
LINE-1 transcription in round spermatids is associated with accretion of 5-carboxylcytosine in their open reading frames. PMID:34099857
Sequencing and comparative genome analysis of three Indians. PMID:34086082
The Rhox gene cluster suppresses germline LINE1 transposition. PMID:34083437
Losing DNA methylation at repetitive elements and breaking bad. PMID:34082816
Genetics, its role in preventing the pandemic of coronary artery disease. PMID:34080689
Infection by Diverse HIV-1 Subtypes Leads to Different Elevations in HERV-K Transcriptional Levels in Human T Cell Lines. PMID:34079529
Human Endogenous Retrovirus as Therapeutic Targets in Neurologic Disease. PMID:34073730
Alternate Roles of Sox Transcription Factors beyond Transcription Initiation. PMID:34073089
Triazole-Modified Nucleic Acids for the Application in Bioorganic and Medicinal Chemistry. PMID:34073038
THAP9 Transposase Cleaves DNA via Conserved Acidic Residues in an RNaseH-Like Domain. PMID:34072453
Malaria in the 'Omics Era'. PMID:34070769
Widespread Exaptation of L1 Transposons for Transcription Factor Binding in Breast Cancer. PMID:34070697
Implementing Pharmacogenomics Testing: Single Center Experience at Arkansas Children's Hospital. PMID:34064668
Proteomics, Personalized Medicine and Cancer. PMID:34063807
Ancient Adversary - HERV-K (HML-2) in Cancer. PMID:34055625
IgG and IgA autoantibodies against L1 ORF1p expressed in granulocytes correlate with granulocyte consumption and disease activity in pediatric systemic lupus erythematosus. PMID:34051843
Emerging Classes of Small Non-Coding RNAs With Potential Implications in Diabetes and Associated Metabolic Disorders. PMID:34040585
Genetic effects on liver chromatin accessibility identify disease regulatory variants. PMID:34038741
Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments. PMID:34029068
Overexpression of Endogenous Retroviruses and Malignancy Markers in Neuroblastoma Cell Lines by Medium-Induced Microenvironmental Changes. PMID:34026614
Organ-, sex- and age-dependent patterns of endogenous L1 mRNA expression at a single locus resolution. PMID:34023901
The Worldwide Invasion of Drosophila suzukii Is Accompanied by a Large Increase of Transposable Element Load and a Small Number of Putatively Adaptive Insertions. PMID:34021759
Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis. PMID:34021236
Chromatin-associated MRN complex protects highly transcribing genes from genomic instability. PMID:34020942
Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus. PMID:34019642
Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation. PMID:34017052
Placental outcomes of phthalate exposure. PMID:34015474
Roles of long non‑coding RNA in osteoarthritis (Review). PMID:34013375
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. PMID:34012113
Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity. PMID:34011996
Transcriptome Analyses Implicate Endogenous Retroviruses Involved in the Host Antiviral Immune System through the Interferon Pathway. PMID:34009516
In vivo discovery of RNA proximal proteins via proximity-dependent biotinylation. PMID:34006179
Analysis of Genomic DNA from Medieval Plague Victims Suggests Long-Term Effect of Yersinia pestis on Human Immunity Genes. PMID:34002224
Identification of Differentially Expressed Human Endogenous Retrovirus Families in Human Leukemia and Lymphoma Cell Lines and Stem Cells. PMID:33996550
Enabling Genomics Pipelines in Commodity Personal Computers With Flash Storage. PMID:33995473
DoChaP: the domain change presenter. PMID:33988713
Dissecting polygenic signals from genome-wide association studies on human behaviour. PMID:33986517
Evolution of default genetic control mechanisms. PMID:33984070
High throughput quantification of short nucleic acid samples by capillary electrophoresis with automated data processing. PMID:33979658
Overexpression of ZNF460 predicts worse survival and promotes metastasis through JAK2/STAT3 signaling pathway in patient with colon cancer. PMID:33976729
The Transposable Element Environment of Human Genes Differs According to Their Duplication Status and Essentiality. PMID:33973013
Endogenous retroviruses in the origins and treatment of cancer. PMID:33971937
A Population-Specific Major Allele Reference Genome From The United Arab Emirates Population. PMID:33968136
Toward Genome-Based Selection in Asian Seabass: What Can We Learn From Other Food Fishes and Farm Animals? PMID:33968125
A Human Endogenous Bornavirus-Like Nucleoprotein Encodes a Mitochondrial Protein Associated with Cell Viability. PMID:33952640
Genomic Tackling of Human Satellite DNA: Breaking Barriers through Time. PMID:33946766
Adhesion GPR123 is an indicator for recurrence and prognosis in bladder cancer. PMID:33945147
Targeting DDX3X Triggers Antitumor Immunity via a dsRNA-Mediated Tumor-Intrinsic Type I Interferon Response. PMID:33941613
The genomic history of the Aegean palatial civilizations. PMID:33930288
The Need for a Human Pangenome Reference Sequence. PMID:33929893
The Startling Role of Mismatch Repair in Trinucleotide Repeat Expansions. PMID:33925919
The "Genomic Code": DNA Pervasively Moulds Chromatin Structures Leaving no Room for "Junk". PMID:33924668
Genetic Diversity and Population Structures in Chinese Miniature Pigs Revealed by SINE Retrotransposon Insertion Polymorphisms, a New Type of Genetic Markers. PMID:33921134
In Vivo and In Vitro Assays Evaluating the Biological Activity of Taurine, Glucose and Energetic Beverages. PMID:33920365
The Involvement of Long Non-Coding RNAs in Bone. PMID:33920083
Sequence, Chromatin and Evolution of Satellite DNA. PMID:33919233
Human Endogenous Retroviruses in Glioblastoma Multiforme. PMID:33917421
Behind the Scenes of the Human Breast Cell Atlas Project. PMID:33914224
Towards complete and error-free genome assemblies of all vertebrate species. PMID:33911273
Chromosome-scale assembly and analysis of biomass crop Miscanthus lutarioriparius genome. PMID:33911077
Virus-derived variation in diverse human genomes. PMID:33901175
MicroRNAs as theranostic markers in cardiac allograft transplantation: from murine models to clinical practice. PMID:33897899
Sensing of transposable elements by the antiviral innate immune system. PMID:33888553
Evolution of genetic networks for human creativity. PMID:33879864
Advances in epigenetic therapeutics with focus on solid tumors. PMID:33879235
FINDER: an automated software package to annotate eukaryotic genes from RNA-Seq data and associated protein sequences. PMID:33879057
Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells. PMID:33872335
Sequence deeper without sequencing more: Bayesian resolution of ambiguously mapped reads. PMID:33872311
Unearthing LTR Retrotransposon gag Genes Co-opted in the Deep Evolution of Eukaryotes. PMID:33871607
Androgen Receptor-Related Non-coding RNAs in Prostate Cancer. PMID:33869227
Role of DNA Methylation in Mediating Genetic Risk of Psychiatric Disorders. PMID:33868039
A total of 219 metagenome-assembled genomes of microorganisms from Icelandic marine waters. PMID:33859876
HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy. PMID:33858848
Mechanisms of enhancer action: the known and the unknown. PMID:33858480
Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice. PMID:33857179
Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases. PMID:33856594
Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model. PMID:33850167
Computational prediction of potential siRNA and human miRNA sequences to silence orf1ab associated genes for future therapeutics against SARS-CoV-2. PMID:33846694
DNA methylation patterns expose variations in enhancer-chromatin modifications during embryonic stem cell differentiation. PMID:33844685
Horizons in Veterinary Precision Oncology: Fundamentals of Cancer Genomics and Applications of Liquid Biopsy for the Detection, Characterization, and Management of Cancer in Dogs. PMID:33834049
Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia. PMID:33833453
A study of transposable element-associated structural variations (TASVs) using a de novo-assembled Korean genome. PMID:33833373
GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data. PMID:33830196
The structure, function and evolution of a complete human chromosome 8. PMID:33828295
A ride through the epigenetic landscape: aging reversal by reprogramming. PMID:33825176
PCIP-seq: simultaneous sequencing of integrated viral genomes and their insertion sites with long reads. PMID:33823910
Low Diversity of Human Variation Despite Mostly Mild Functional Impact of De Novo Variants. PMID:33816556
DEEPGENTM-A Novel Variant Calling Assay for Low Frequency Variants. PMID:33808158
Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study. PMID:33807474
Construction of Whole Genomes from Scaffolds Using Single Cell Strand-Seq Data. PMID:33807210
Non-Coding RNAs in Cancer Diagnosis and Therapy: Focus on Lung Cancer. PMID:33803619
How Chaotic Is Genome Chaos? PMID:33802828
Viroids and the Origin of Life. PMID:33800543
Flowering and Seed Production across the Lemnaceae. PMID:33800476
Palindromes in DNA-A Risk for Genome Stability and Implications in Cancer. PMID:33799581
The Impact of Modern Technologies on Molecular Diagnostic Success Rates, with a Focus on Inherited Retinal Dystrophy and Hearing Loss. PMID:33799353
The next horizon in precision oncology: Proteogenomics to inform cancer diagnosis and treatment. PMID:33798439
Variable number tandem repeats - Their emerging role in sickness and health. PMID:33794697
Pervasive cis effects of variation in copy number of large tandem repeats on local DNA methylation and gene expression. PMID:33794196
Large vs small genomes in Passiflora: the influence of the mobilome and the satellitome. PMID:33792791
Alternative splicing of lncRNAs in human diseases. PMID:33791145
Diversity of short interspersed nuclear elements (SINEs) in lepidopteran insects and evidence of horizontal SINE transfer between baculovirus and lepidopteran hosts. PMID:33789582
X-ray Ptychography Imaging of Human Chromosomes After Low-dose Irradiation. PMID:33786705
Genetic Risk Stratification: A Paradigm Shift in Prevention of Coronary Artery Disease. PMID:33778213
Opportunities and challenges of artificial intelligence in the medical field: current application, emerging problems, and problem-solving strategies. PMID:33771068
The evolution of patient-specific precision biomarkers to guide personalized heart-transplant care. PMID:33768160
Mechanisms of Action of Hypomethylating Agents: Endogenous Retroelements at the Epicenter. PMID:33768008
Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS. PMID:33767386
Consequences for Pancreatic β-Cell Identity and Function of Unregulated Transcript Processing. PMID:33763030
Noncanonical immune response to the inhibition of DNA methylation by Staufen1 via stabilization of endogenous retrovirus RNAs. PMID:33762305
G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease. PMID:33758195
Dissecting the transcriptome in cardiovascular disease. PMID:33757121
The functional impact of nuclear reorganization in cellular senescence. PMID:33755107
Evolutionary conservation of RNA sequence and structure. PMID:33754485
Identification of 11 candidate structured noncoding RNA motifs in humans by comparative genomics. PMID:33750298
Advancing drug discovery using the power of the human genome. PMID:33748968
Short and long-read genome sequencing methodologies for somatic variant detection; genomic analysis of a patient with diffuse large B-cell lymphoma. PMID:33742045
Exosomal Long Non-coding RNAs: Emerging Players in the Tumor Microenvironment. PMID:33738133
Genomic regions associated with microdeletion/microduplication syndromes exhibit extreme diversity of structural variation. PMID:33724415
Pinpointing the PRDM9-PRDM7 Gene Duplication Event During Primate Divergence. PMID:33719332
Reconsidering LINE-1's role in cancer: does LINE-1 function as a reporter detecting early cancer-associated epigenetic signatures? PMID:33717489
Aptardi predicts polyadenylation sites in sample-specific transcriptomes using high-throughput RNA sequencing and DNA sequence. PMID:33712618
Assessing the contribution of tumor mutational phenotypes to cancer progression risk. PMID:33711014
From the discovery of DNA to current tools for DNA editing. PMID:33710258
Retroviral Elements in Human Evolution and Neural Development. PMID:33693440
Interrogating lncRNA functions via CRISPR/Cas systems. PMID:33685382
Localization of RNAs in the nucleus: cis- and trans- regulation. PMID:33682620
Altered DNA repair creates novel Alu/Alu repeat-mediated deletions. PMID:33675284
Identification of Germline Genetic Variants that Increase Prostate Cancer Risk and Influence Development of Aggressive Disease. PMID:33673083
Meta-Analysis of Gene Popularity: Less Than Half of Gene Citations Stem from Gene Regulatory Networks. PMID:33672419
Transposable Elements and Stress in Vertebrates: An Overview. PMID:33671215
Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus. PMID:33669709
Genetic Mechanisms Underlying Cortical Evolution in Mammals. PMID:33659245
Structural variant detection in cancer genomes: computational challenges and perspectives for precision oncology. PMID:33654267
An update of KAIKObase, the silkworm genome database. PMID:33645624
From Genome-Wide to Environment-Wide: Capturing the Environome. PMID:33645332
A Mechanism Leading to Changes in Copy Number Variations Affected by Transcriptional Level Might Be Involved in Evolution, Embryonic Development, Senescence, and Oncogenesis Mediated by Retrotransposons. PMID:33644055
Gene Size Matters: An Analysis of Gene Length in the Human Genome. PMID:33643374
VISTA: A Target to Manage the Innate Cytokine Storm. PMID:33643285
Methylation status and long-fragment cell-free DNA are prognostic biomarkers for gastric cancer. PMID:33641249
Haplotype-resolved diverse human genomes and integrated analysis of structural variation. PMID:33632895
Epigenetics of cutaneous T-cell lymphoma: biomarkers and therapeutic potentials. PMID:33628583
Closing in on a complete human genome. PMID:33619406
Elucidation of Epigenetic Landscape in Coronary Artery Disease: A Review on Basic Concept to Personalized Medicine. PMID:33598635
The Impact of Purifying and Background Selection on the Inference of Population History: Problems and Prospects. PMID:33591322
SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans. PMID:33587037
SARS-CoV-2 Proteins Exploit Host's Genetic and Epigenetic Mediators for the Annexation of Key Host Signaling Pathways. PMID:33585554
Mammalian Germ Cell Development: From Mechanism to In Vitro Reconstitution. PMID:33577794
Fatal perinatal mitochondrial cardiac failure caused by recurrent de novo duplications in the ATAD3 locus. PMID:33575671
A random forest-based framework for genotyping and accuracy assessment of copy number variations. PMID:33575619
Benchmark study comparing liftover tools for genome conversion of epigenome sequencing data. PMID:33575605
Five Circular RNAs in Metabolism Pathways Related to Prostate Cancer. PMID:33574834
Sense-oriented AluYRa1 elements provide a lineage-specific transcription environment for polyadenylation. PMID:33574427
Early life stress during the neonatal period alters social play and Line1 during the juvenile stage of development. PMID:33574362
LAMA: automated image analysis for the developmental phenotyping of mouse embryos. PMID:33574040
Systemic Lupus Erythematosus in Children and Young People. PMID:33569643
The broken promise that undermines human genome research. PMID:33568833
How the human genome transformed study of rare diseases. PMID:33568830
A wealth of discovery built on the Human Genome Project - by the numbers. PMID:33568828
From one human genome to a complex tapestry of ancestry. PMID:33568827
Breaking through the unknowns of the human reference genome. PMID:33568817
The Cancer Genome: Paradigm or Paradox? PMID:33567511
A mesoscopic simulator to uncover heterogeneity and evolutionary dynamics in tumors. PMID:33566821
L1 retrotransposons exploit RNA m6A modification as an evolutionary driving force. PMID:33563981
Evolution of genome structure in the Drosophila simulans species complex. PMID:33563718
RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs. PMID:33563338
Role of Transposable Elements in Gene Regulation in the Human Genome. PMID:33557056
Human endogenous retroviruses in cancer: Expression, regulation and function. PMID:33552242
Sea Urchin as a Universal Model for Studies of Gene Networks. PMID:33552139
Genomic Variation, Evolvability, and the Paradox of Mental Illness. PMID:33551865
Invasive and Noninvasive Nonfunctioning Gonadotroph Pituitary Tumors Differ in DNA Methylation Level of LINE-1 Repetitive Elements. PMID:33546126
Potential APOBEC-mediated RNA editing of the genomes of SARS-CoV-2 and other coronaviruses and its impact on their longer term evolution. PMID:33545556
Evolutionary dynamics of transposable elements in bdelloid rotifers. PMID:33543711
Complicated legacies: The human genome at 20. PMID:33542123
Creating artificial human genomes using generative neural networks. PMID:33539374
Benchmarking of next and third generation sequencing technologies and their associated algorithms for de novo genome assembly. PMID:33537807
Methods for Proteogenomics Data Analysis, Challenges, and Scalability Bottlenecks: A Survey. PMID:33537181
BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2-RAD52. PMID:33536619
Circular RNA circPIKfyve acts as a sponge of miR-21-3p to enhance antiviral immunity through regulating MAVS in teleost fish. PMID:33536171
Impact of short-read sequencing on the misassembly of a plant genome. PMID:33530937
Targeted next-generation sequencing-based detection of microsatellite instability in colorectal carcinomas. PMID:33524032
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome. PMID:33514913
Noncanonical open reading frames encode functional proteins essential for cancer cell survival. PMID:33510483
tsRNAs: Novel small molecules from cell function and regulatory mechanism to therapeutic targets. PMID:33507586
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA. PMID:33506766
Complete sequences of Schizosaccharomyces pombe subtelomeres reveal multiple patterns of genome variation. PMID:33504776
The impact of purifying and background selection on the inference of population history: problems and prospects. PMID:33501439
The search for RNA-binding proteins: a technical and interdisciplinary challenge. PMID:33492363
Genomic Study of COVID-19 Corona Virus Excludes Its Origin from Recombination or Characterized Biological Sources and Suggests a Role for HERVS in Its Wide Range Symptoms. PMID:33487779
Intercellular Communication in the Nervous System Goes Viral. PMID:33485691
Machine learning as the new approach in understanding biomarkers of suicidal behavior. PMID:33485296
Estimating the accuracy of pharmacophore-based detection of cognate receptor-ligand pairs in the immunoglobulin superfamily. PMID:33483991
A comprehensive microsatellite landscape of human Y-DNA at kilobase resolution. PMID:33482734
Control of LINE-1 Expression Maintains Genome Integrity in Germline and Early Embryo Development. PMID:33481218
Epigenetic and non-coding regulation of alcohol abuse and addiction. PMID:33461665
The Texas Society of Pathologists: molded by the legacy of pathology and focused on excellence in medicine for 100 years and beyond. PMID:33456200
50th anniversary of the discovery of reverse transcriptase. PMID:33448895
Recognize Yourself-Innate Sensing of Non-LTR Retrotransposons. PMID:33445593
A Highly Conserved Circular RNA circRasGEF1B Enhances Antiviral Immunity by Regulating miR-21-3p/MITA Pathway in Lower Vertebrates. PMID:33441345
Genome diversity in Ukraine. PMID:33438729
The Dfam community resource of transposable element families, sequence models, and genome annotations. PMID:33436076
Multiple Alu Exonization in 3'UTR of a Primate-Specific Isoform of CYP20A1 Creates a Potential miRNA Sponge. PMID:33434274
Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference. PMID:33431880
Half a century of the reverse transcriptase-happy birthday! PMID:33430901
Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2. PMID:33413422
Transposable element-derived sequences in vertebrate development. PMID:33407840
Signature changes in the expressions of protein-coding genes, lncRNAs, and repeat elements in early and late cellular senescence. PMID:33402863
TFs for TEs: the transcription factor repertoire of mammalian transposable elements. PMID:33397727
Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer. PMID:33397425
Probably Correct: Rescuing Repeats with Short and Long Reads. PMID:33396198
Alu retrotransposons and COVID-19 susceptibility and morbidity. PMID:33390179
Seeing the forest for the trees: Retrieving plant secondary biochemical pathways from metabolome networks. PMID:33384856
Transcript assembly improves expression quantification of transposable elements in single-cell RNA-seq data. PMID:33355230
Integrative Analysis of Gene-Specific DNA Methylation and Untargeted Metabolomics Data from the ELEMENT Cohort. PMID:33354655
Gene regulation by long non-coding RNAs and its biological functions. PMID:33353982
Adaptive evolution of an essential telomere protein restricts telomeric retrotransposons. PMID:33350936
Factors that mold the nuclear landscape of HIV-1 integration. PMID:33337475
Effects of activation of the LINE-1 antisense promoter on the growth of cultured cells. PMID:33335226
Use of Genomic Information in Health Impact Assessment is Yet to Come: A Systematic Review. PMID:33334033
Involvement of DNA Repair Genes and System of Radiation-Induced Activation of Transposons in Formation of Transgenerational Effects. PMID:33329741
Antifreeze protein dispersion in eelpouts and related fishes reveals migration and climate alteration within the last 20 Ma. PMID:33320906
GAS5 regulates diabetic cardiomyopathy via miR‑221‑3p/p27 axis‑associated autophagy. PMID:33313941
Pioneer-like factor GAF cooperates with PBAP (SWI/SNF) and NURF (ISWI) to regulate transcription. PMID:33303640
Identification of Long Noncoding RNA Biomarkers for Hepatocellular Carcinoma Using Single-Sample Networks. PMID:33299877
Genotyping of Francisella tularensis subsp. holarctica from Hares in Germany. PMID:33291395
NGS-based identification and tracing of microsatellite instability from minute amounts DNA using inter-Alu-PCR. PMID:33290560
Accurate assembly of the olive baboon (Papio anubis) genome using long-read and Hi-C data. PMID:33283855
How Retroviruses and Retrotransposons in Our Genome May Contribute to Autoimmunity in Rheumatological Conditions. PMID:33281822
Epigenetic Alterations in the Gastrointestinal Tract: Current and Emerging Use for Biomarkers of Cancer. PMID:33279516
Striking heterogeneity of somatic L1 retrotransposition in single normal and cancerous gastrointestinal cells. PMID:33277430
Building genomes to understand biology. PMID:33268788
A novel computational model for predicting potential LncRNA-disease associations based on both direct and indirect features of LncRNA-disease pairs. PMID:33267800
Deep Learning in LncRNAome: Contribution, Challenges, and Perspectives. PMID:33266128
The Role of APOBECs in Viral Replication. PMID:33266042
Developmental differences in genome replication program and origin activation. PMID:33264404
FTH1 Pseudogenes in Cancer and Cell Metabolism. PMID:33260500
'There and Back Again'-Forward Genetics and Reverse Phenotyping in Pulmonary Arterial Hypertension. PMID:33256119
Evaluating the Genomic Parameters Governing rAAV-Mediated Homologous Recombination. PMID:33248247
Evaluation of the upper airway microbiome and immune response with nasal epithelial lining fluid absorption and nasal washes. PMID:33244064
CircRNAs open a new era in the study of cardiovascular disease (Review). PMID:33236162
Challenges of Precision Medicine for Atherosclerotic Cardiovascular Disease Based on Human Genome Information. PMID:33229815
Identification of the novel Np17 oncogene in human leukemia. PMID:33226963
Perversely expressed long noncoding RNAs can alter host response and viral proliferation in SARS-CoV-2 infection. PMID:33224264
Identification of high-copy number long terminal repeat retrotransposons and their expansion in Phalaenopsis orchids. PMID:33213366
Structure of the Receptor Binding Domain of EnvP(b)1, an Endogenous Retroviral Envelope Protein Expressed in Human Tissues. PMID:33203760
LC-N2G: a local consistency approach for nutrigenomics data analysis. PMID:33203358
Human Endogenous Retrovirus K Rec forms a Regulatory Loop with MITF that Opposes the Progression of Melanoma to an Invasive Stage. PMID:33202765
Hotspots of Human Mutation. PMID:33199048
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression. PMID:33197463
Exploring the changing geographical pattern of international scientific collaborations through the prism of cities. PMID:33196668
Endoplasmic Reticulum Associated Protein Degradation (ERAD) in the Pathology of Diseases Related to TGFβ Signaling Pathway: Future Therapeutic Perspectives. PMID:33195419
Establishment of Quantitative PCR Assays for Active Long Interspersed Nuclear Element-1 Subfamilies in Mice and Applications to the Analysis of Aging-Associated Retrotransposition. PMID:33193604
GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline. PMID:33193602
The Role of DNA Methylation in Ischemic Stroke: A Systematic Review. PMID:33193003
E3 Ubiquitin Ligases in Neurological Diseases: Focus on Gigaxonin and Autophagy. PMID:33192535
High levels of LINE-1 transposable elements expressed in Kaposi's sarcoma-associated herpesvirus-related primary effusion lymphoma. PMID:33188297
Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis. PMID:33187550
A SINE-VNTR-Alu in the LRIG2 Promoter Is Associated with Gene Expression at the Locus. PMID:33187279
The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition. PMID:33177501
Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy. PMID:33173052
LINE-1 retrotransposon methylation in chorionic villi of first trimester miscarriages with aneuploidy. PMID:33170392
Modes of genetic adaptations underlying functional innovations in the rumen. PMID:33165812
Using Drosophila melanogaster To Discover Human Disease Genes: An Educational Primer for Use with "Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target". PMID:33158986
Clinical Interpretation and Management of Genetic Variants. PMID:33145465
Ensembl 2021. PMID:33137190
Effects of zinc finger protein 403 on the proliferation, migration and invasion abilities of prostate cancer cells. PMID:33125130
Identification of bona fide B2 SINE retrotransposon transcription through single-nucleus RNA-seq of the mouse hippocampus. PMID:33122305
Strategic vision for improving human health at The Forefront of Genomics. PMID:33116284
Raw transcriptomics data to gene specific SSRs: a validated free bioinformatics workflow for biologists. PMID:33106560
Comprehensive Transcriptome Profiling of Dairy Goat Mammary Gland Identifies Genes and Networks Crucial for Lactation and Fatty Acid Metabolism. PMID:33101357
Genomic and Transcriptomic Analyses of Bioluminescence Genes in the Enope Squid Watasenia scintillans. PMID:33098466
Beyond the RNA-dependent function of LncRNA genes. PMID:33095159
Genome streamlining in a minute herbivore that manipulates its host plant. PMID:33095158
Twenty Years Later: A Comprehensive Review of the X Chromosome Use in Forensic Genetics. PMID:33093840
A Journey through Genetic Architecture and Predisposition of Coronary Artery Disease. PMID:33093801
Genetic Aspects in Shoulder Disorders. PMID:33093716
Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression. PMID:33087347
Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies. PMID:33084892
Evolutionary History of Alpha Satellite DNA Repeats Dispersed within Human Genome Euchromatin. PMID:33078196
Next Generation Sequencing Based Forward Genetic Approaches for Identification and Mapping of Causal Mutations in Crop Plants: A Comprehensive Review. PMID:33066352
An Intronic Alu Element Attenuates the Transcription of a Long Non-coding RNA in Human Cell Lines. PMID:33061937
p53 directly represses human LINE1 transposons. PMID:33060137
Whole genome sequencing data of multiple individuals of Pakistani descent. PMID:33051442
RNA editing in mesothelioma: a look forward. PMID:33050791
The Nucleome Data Bank: web-based resources to simulate and analyze the three-dimensional genome. PMID:33021634
Posttranscriptional regulation of human endogenous retroviruses by RNA-binding motif protein 4, RBM4. PMID:33020268
New Aspects of the Epigenetics of Pancreatic Carcinogenesis. PMID:33014438
Variants of significance: medical genetics and surgical outcomes in congenital heart disease. PMID:33009125
Immunological Features with DNA Microsatellite Alterations in Patients with Colorectal Cancer. PMID:33000102
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D. PMID:32999275
RNA-cDNA hybrids mediate transposition via different mechanisms. PMID:32994470
Reconstruction of lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveals functional lncRNAs in skin cutaneous melanoma. PMID:32993558
Host Gene Regulation by Transposable Elements: The New, the Old and the Ugly. PMID:32993145
tRNA-Derived Small RNAs: Novel Epigenetic Regulators. PMID:32992597
Tissue-specific usage of transposable element-derived promoters in mouse development. PMID:32988383
The Role of Micro-RNAs and Circulating Tumor Markers as Predictors of Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer. PMID:32987896
A Model-Driven Quantitative Analysis of Retrotransposon Distributions in the Human Genome. PMID:32986810
Transposon expression in the Drosophila brain is driven by neighboring genes and diversifies the neural transcriptome. PMID:32973040
Non-Coding RNAs, a Novel Paradigm for the Management of Gastrointestinal Stromal Tumors. PMID:32972022
Connecting the Missing Dots: ncRNAs as Critical Regulators of Therapeutic Susceptibility in Breast Cancer. PMID:32967267
Prioritizing sequence variants in conserved non-coding elements in the chicken genome using chCADD. PMID:32966296
Transposon clusters as substrates for aberrant splice-site activation. PMID:32965162
Comprehensive genomic analysis reveals dynamic evolution of endogenous retroviruses that code for retroviral-like protein domains. PMID:32963593
Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing. PMID:32962098
Predicting Response to Immunotherapy in Metastatic Renal Cell Carcinoma. PMID:32961934
A multi-omics approach to solving problems in plant disease ecology. PMID:32960892
Analysis, identification and visualization of subgroups in genomics. PMID:32954413
Intronic regions of the human coagulation factor VIII gene harboring transcription factor binding sites with a strong bias towards the short-interspersed elements. PMID:32944665
Nucleotide sequencing of the HoxA gene cluster using Gorilla fosmid clones. PMID:32934753
ZBED1/DREF: A transcription factor that regulates cell proliferation. PMID:32934705
Immune activation by a multigene family of lectins with variable tandem repeats in oriental river prawn (Macrobrachium nipponense). PMID:32931720
Mouse tumor susceptibility genes identify drug combinations for multiple myeloma. PMID:32923678
Block and Lock HIV Cure Strategies to Control the Latent Reservoir. PMID:32923412
TIP_finder: An HPC Software to Detect Transposable Element Insertion Polymorphisms in Large Genomic Datasets. PMID:32917036
Mosaicism in Human Health and Disease. PMID:32916079
At the dawn of the transcriptomic medicine. PMID:32915637
Chromonomer: A Tool Set for Repairing and Enhancing Assembled Genomes Through Integration of Genetic Maps and Conserved Synteny. PMID:32912931
Differences between human and chimpanzee genomes and their implications in gene expression, protein functions and biochemical properties of the two species. PMID:32912141
Proteomic Analysis of Human Endometrial Tissues Reveals the Roles of PI3K/AKT/mTOR Pathway and Tumor Angiogenesis Molecules in the Pathogenesis of Endometrial Cancer. PMID:32908897
Evaluation of Plasma Circulating Cell Free DNA Concentration and Integrity in Patients with Prostate Cancer in Jamaica: A Preliminary Study. PMID:32906694
Next-Generation Sequencing at High Sequencing Depth as a Tool to Study the Evolution of Metastasis Driven by Genetic Change Events of Lung Squamous Cell Carcinoma. PMID:32903616
Use of an Exposome Approach to Understand the Effects of Exposures From the Natural, Built, and Social Environments on Cardio-Vascular Disease Onset, Progression, and Outcomes. PMID:32903514
An Overview of Duplicated Gene Detection Methods: Why the Duplication Mechanism Has to Be Accounted for in Their Choice. PMID:32899740
Endogenous retroviruses drive species-specific germline transcriptomes in mammals. PMID:32895553
Aberrant Methylation of LINE-1 Transposable Elements: A Search for Cancer Biomarkers. PMID:32887319
Yersinia pestis strains from Latvia show depletion of the pla virulence gene at the end of the second plague pandemic. PMID:32884081
Replication stress at microsatellites causes DNA double-strand breaks and break-induced replication. PMID:32873711
Reverse Transcriptase Affects Gametogenesis and Preimplantation Development in Mouse. PMID:32871749
Characterization and Localization of Calb2 in Both the Testis and Ovary of the Japanese Flounder (Paralichthys olivaceus). PMID:32858799
Lamivudine Inhibits Alu RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities. PMID:32855848
Molecular Characterization of Testicular Germ Cell Tumors Using Tissue Microdissection. PMID:32852755
New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation. PMID:32850797
Forensic Autosomal Short Tandem Repeats and Their Potential Association With Phenotype. PMID:32849844
Background Selection Does Not Mimic the Patterns of Genetic Diversity Produced by Selective Sweeps. PMID:32847814
Potential of transposon-mediated cellular reprogramming towards cell-based therapies. PMID:32843912
Pan-genomic open reading frames: A potential supplement of single nucleotide polymorphisms in estimation of heritability and genomic prediction. PMID:32833967
A report on DNA sequence determinants in gene expression. PMID:32831525
Application of Next Generation Sequencing in Laboratory Medicine. PMID:32829577
Silencing and Transcriptional Regulation of Endogenous Retroviruses: An Overview. PMID:32823517
Untangling Data in Precision Oncology - A Model for Chronic Diseases? PMID:32823314
Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors. PMID:32822573
Presence of Endogenous Viral Elements Negatively Correlates with Feline Leukemia Virus Susceptibility in Puma and Domestic Cat Cells. PMID:32817213
Cryptic genetic variation enhances primate L1 retrotransposon survival by enlarging the functional coiled coil sequence space of ORF1p. PMID:32797042
The Prospective Study of Epigenetic Regulatory Profiles in Sport and Exercise Monitored Through Chromosome Conformation Signatures. PMID:32784689
Trypanosoma cruzi Genome 15 Years Later: What Has Been Accomplished? PMID:32781761
The Long Non-coding Road to Atherosclerosis. PMID:32772181
The Human Genome Project changed everything. PMID:32770171
Polygenic risk score as clinical utility in psychiatry: a clinical viewpoint. PMID:32770057
A First NGS Investigation Suggests No Association Between Viruses and Canine Cancers. PMID:32766289
Analysis of Salmonella typhimurium Protein-Targeting in the Nucleus of Host Cells and the Implications in Colon Cancer: An in-silico Approach. PMID:32765017
Comparative genomic analysis of eutherian fibroblast growth factor genes. PMID:32758140
Whole Genome Sequencing of Four Representatives From the Admixed Population of the United Arab Emirates. PMID:32754195
Proteomics and Metabolomics for Cystic Fibrosis Research. PMID:32751630
Single-cell proteomic analysis. PMID:32748522
Genomic Diagnosis for Pediatric Disorders: Revolution and Evolution. PMID:32733828
Tumor DNA hypomethylation of LINE-1 is associated with low tumor grade of breast cancer in Tunisian patients. PMID:32724446
Human L1 Transposition Dynamics Unraveled with Functional Data Analysis. PMID:32722770
How Dietary Factors Affect DNA Methylation: Lesson from Epidemiological Studies. PMID:32722411
Endogenous Retroviruses Walk a Fine Line between Priming and Silencing. PMID:32718022
How Will Genetics Inform the Clinical Care of Atrial Fibrillation? PMID:32716712
BIOMAP: A Home for All Biology Methods. PMID:32715089
Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci. PMID:32709900
Consequence of Paradigm Shift with Repeat Landscapes in Reptiles: Powerful Facilitators of Chromosomal Rearrangements for Diversity and Evolution. PMID:32708239
Brain cell somatic gene recombination and its phylogenetic foundations. PMID:32699111
Prostate cancer biology & genomics. PMID:32676435
Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway. PMID:32669437
Human Cancers Express TRAILshort, a Dominant Negative TRAIL Splice Variant, Which Impairs Immune Effector Cell Killing of Tumor Cells. PMID:32669373
A deliberative study of public attitudes towards sharing genomic data within NHS genomic medicine services in England. PMID:32664786
Telomere-to-telomere assembly of a complete human X chromosome. PMID:32663838
Identification and Genotyping of Transposable Element Insertions From Genome Sequencing Data. PMID:32662945
Regulation of Error-Prone DNA Double-Strand Break Repair and Its Impact on Genome Evolution. PMID:32660124
Cancer systems immunology. PMID:32657757
Maximal Segmental Score Method for Localizing Recessive Disease Variants Based on Sequence Data. PMID:32655614
Enhancer Function of MicroRNA-3681 Derived from Long Terminal Repeats Represses the Activity of Variable Number Tandem Repeats in the 3' UTR of SHISA7. PMID:32655015
Cancer Associated Endogenous Retroviruses: Ideal Immune Targets for Adenovirus-Based Immunotherapy. PMID:32650622
Non-Coding RNA Editing in Cancer Pathogenesis. PMID:32650588
Chromosome-level de novo assembly of the pig-tailed macaque genome using linked-read sequencing and HiC proximity scaffolding. PMID:32649757
Higher Germline Mutagenesis of Genes with Stronger Testis Expressions Refutes the Transcriptional Scanning Hypothesis. PMID:32638015
Strategies for whole-exome sequencing analysis in a case series study of familial male infertility. PMID:32637866
Handling multi-mapped reads in RNA-seq. PMID:32637053
Transposable elements in Drosophila. PMID:32636946
mRNA Editing, Processing and Quality Control in Caenorhabditis elegans. PMID:32632025
Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual. PMID:32631951
Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns. PMID:32631327
Pro-Inflammatory Signaling Upregulates a Neurotoxic Conotoxin-Like Protein Encrypted Within Human Endogenous Retrovirus-K. PMID:32629888
Nasopharyngeal Haemophilus and local immune response during infant respiratory syncytial virus infection. PMID:32628963
Breathing fresh air into respiratory research with single-cell RNA sequencing. PMID:32620586
Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. PMID:32616928
Desiccation does not drastically increase the accessibility of exogenous DNA to nuclear genomes: evidence from the frequency of endosymbiotic DNA transfer. PMID:32611311
LDtrait: An Online Tool for Identifying Published Phenotype Associations in Linkage Disequilibrium. PMID:32606005
Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis. PMID:32603313
Multiple Invasions of Visitor, a DD41D Family of Tc1/mariner Transposons, throughout the Evolution of Vertebrates. PMID:32602886
Retrotransposons in pluripotent stem cells. PMID:32588192
The IRI-DICE hypothesis: ionizing radiation-induced DSBs may have a functional role for non-deterministic responses at low doses. PMID:32583290
Infectious Triggers in Periodontitis and the Gut in Rheumatoid Arthritis (RA): A Complex Story About Association and Causality. PMID:32582191
Efavirenz as a potential drug for the treatment of triple-negative breast cancers. PMID:32566961
The Battle to Sequence the Bread Wheat Genome: A Tale of the Three Kingdoms. PMID:32561470
Plasma cell-free DNA predicts pediatric cerebral malaria severity. PMID:32554925
Characteristics of circular RNAs generated by human Survival Motor Neuron genes. PMID:32553550
A comparative study of long interspersed element-1 protein immunoreactivity in cutaneous malignancies. PMID:32552892
High-Throughput Sequencing is a Crucial Tool to Investigate the Contribution of Human Endogenous Retroviruses (HERVs) to Human Biology and Development. PMID:32545287
Closing Human Reference Genome Gaps: Identifying and Characterizing Gap-Closing Sequences. PMID:32532800
Multi-branch Convolutional Neural Network for Identification of Small Non-coding RNA genomic loci. PMID:32528107
Nanopore sequencing as a scalable, cost-effective platform for analyzing polyclonal vector integration sites following clinical T cell therapy. PMID:32527930
DNA methylation patterns of LINE-1 and Alu for pre-symptomatic dementia in type 2 diabetes. PMID:32525932
Single-Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells. PMID:32513898
Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes. PMID:32513296
Long-read human genome sequencing and its applications. PMID:32504078
A single mutation in the ACTR8 gene associated with lineage-specific expression in primates. PMID:32503430
DNA hypomethylation promotes transposable element expression and activation of immune signaling in renal cell cancer. PMID:32493845
Education in the genomics era: Generating high-quality genome assemblies in university courses. PMID:32491162
Hagfish genome reveals parallel evolution of 7SL RNA-derived SINEs. PMID:32489435
Assembly and annotation of an Ashkenazi human reference genome. PMID:32487205
SETDB1-Mediated Silencing of Retroelements. PMID:32486217
Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates. PMID:32479260
The functional cooperation of 5-HT1A and mGlu4R in HEK-293 cell line. PMID:32472388
The quest to slow ageing through drug discovery. PMID:32467649
Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer's Disease. PMID:32457796
Vertical lossless genomic data compression tools for assembled genomes: A systematic literature review. PMID:32453750
Sawfly Genomes Reveal Evolutionary Acquisitions That Fostered the Mega-Radiation of Parasitoid and Eusocial Hymenoptera. PMID:32442304
Non-coding RNAs in Nervous System Development and Disease. PMID:32435641
Viral infection impacts transposable element transcript amounts in Drosophila. PMID:32434916
Reawakening the Developmental Origins of Cancer Through Transposable Elements. PMID:32432029
Mechanisms of Long Non-Coding RNAs in Cancers and Their Dynamic Regulations. PMID:32429086
Review: Understanding Rare Genetic Diseases in Low Resource Regions Like Jammu and Kashmir - India. PMID:32425985
Progress, Challenges, and Surprises in Annotating the Human Genome. PMID:32421357
Genomic Indexing by Somatic Gene Recombination of mRNA/ncRNA - Does It Play a Role in Genomic Mosaicism, Memory Formation, and Alzheimer's Disease? PMID:32411177
High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation. PMID:32408171
Conserved Herpesvirus Kinase ORF36 Activates B2 Retrotransposons during Murine Gammaherpesvirus Infection. PMID:32404524
Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral. PMID:32404186
Effect of sequence depth and length in long-read assembly of the maize inbred NC358. PMID:32385271
Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction. PMID:32383760
A single-cell transcriptomic landscape of primate arterial aging. PMID:32371953
Oxidative Stress in DNA Repeat Expansion Disorders: A Focus on NRF2 Signaling Involvement. PMID:32369911
HiC-Hiker: a probabilistic model to determine contig orientation in chromosome-length scaffolds with Hi-C. PMID:32369554
The Sophisticated Transcriptional Response Governed by Transposable Elements in Human Health and Disease. PMID:32366056
Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation. PMID:32360393
The Simons Genome Diversity Project: A Global Analysis of Mobile Element Diversity. PMID:32359137
Are Pathogenic Germline Variants in Metastatic Melanoma Associated with Resistance to Combined Immunotherapy? PMID:32354124
DNA methylation level in blood and relations to breast cancer, risk factors and environmental exposure in Greenlandic Inuit women. PMID:32352194
Comparison of Behavior and Genetic Structure in Populations of Family and Kenneled Beagles. PMID:32351979
Recent Trends of microRNA Significance in Pediatric Population Glioblastoma and Current Knowledge of Micro RNA Function in Glioblastoma Multiforme. PMID:32349263
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues. PMID:32345368
The functional study of human proteins using humanized yeast. PMID:32342338
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction. PMID:32341350
The science commons in life science research: structure, function, and value of access to genetic diversity. PMID:32336774
A chromosome-scale assembly of the smallest Dothideomycete genome reveals a unique genome compaction mechanism in filamentous fungi. PMID:32326892
Insertion of Telomeric Repeats in the Human and Horse Genomes: An Evolutionary Perspective. PMID:32325780
Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk: Clinical Perspectives and Basic Implications. PMID:32324503
Purification of Bionanoparticles. PMID:32313384
The Biological Functions of Non-coding RNAs: From a Line to a Circle. PMID:32309571
Identification and Ranking of Biomedical Informatics Researcher Citation Statistics through a Google Scholar Scraper. PMID:32308860
Fungal evolution: cellular, genomic and metabolic complexity. PMID:32301582
RepeatModeler2 for automated genomic discovery of transposable element families. PMID:32300014
TranspoScope: interactive visualization of retrotransposon insertions. PMID:32298413
A reference map of the human binary protein interactome. PMID:32296183
Transposable elements contribute to cell and species-specific chromatin looping and gene regulation in mammalian genomes. PMID:32286261
An ancient evolutionary connection between Ribonuclease A and EndoU families. PMID:32284351
Gallop Racing Shifts Mature mRNA towards Introns: Does Exercise-Induced Stress Enhance Genome Plasticity? PMID:32283859
Tumour grade significantly correlates with total dysfunction of tumour tissue-infiltrating lymphocytes in renal cell carcinoma. PMID:32277125
Codon Usage and Splicing Jointly Influence mRNA Localization. PMID:32275854
Systems Biochemistry Approaches to Defining Mitochondrial Protein Function. PMID:32268114
Long Non-coding RNAs: Major Regulators of Cell Stress in Cancer. PMID:32266130
Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins. PMID:32252787
SAMHD1 Functions and Human Diseases. PMID:32244340
DNA methylation profiling identifies a high effect genetic variant for lipoprotein(a) levels. PMID:32237968
Reciprocal regulation between alternative splicing and the DNA damage response. PMID:32236390
Considerations for Using the Vasculature as a Coordinate System to Map All the Cells in the Human Body. PMID:32232057
Differential Responses of LINE-1 in the Dentate Gyrus, Striatum and Prefrontal Cortex to Chronic Neurotoxic Methamphetamine: A Study in Rat Brain. PMID:32231019
The genome-wide landscape of C:G > T:A polymorphism at the CpG contexts in the human population. PMID:32228436
In or Out? New Insights on Exon Recognition through Splice-Site Interdependency. PMID:32225107
Divergence-Based Introgression Polarization. PMID:32219392
Viral component of the human genome. PMID:32214476
Quantification, Dynamic Visualization, and Validation of Bias in ATAC-Seq Data with ataqv. PMID:32213349
How We Think about Targeting RNA with Small Molecules. PMID:32212706
Gene editing and CRISPR in the clinic: current and future perspectives. PMID:32207531
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. PMID:32203508
Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway. PMID:32202492
Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast. PMID:32195249
Discussion of Trial Designs for Biomarker Identification and Validation Through the Use of Case Studies. PMID:32190807
Dynamic LTR retrotransposon transcriptome landscape in septic shock patients. PMID:32188504
Is Gene-Size an Issue for the Diagnosis of Skeletal Muscle Disorders? PMID:32176652
Beyond classic editing: innovative CRISPR approaches for functional studies of long non-coding RNA. PMID:32161809
Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation. PMID:32160538
In Vivo Delivery of Nucleic Acid-Encoded Monoclonal Antibodies. PMID:32157600
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes. PMID:32157095
Dynamic Signatures of the Epigenome: Friend or Foe? PMID:32156057
SECNVs: A Simulator of Copy Number Variants and Whole-Exome Sequences From Reference Genomes. PMID:32153642
Jump around: transposons in and out of the laboratory. PMID:32148769
A-to-I RNA Editing Uncovers Hidden Signals of Adaptive Genome Evolution in Animals. PMID:32145015
Genetic and Genomic Advances in Developmental Models: Applications for Nutrition Research. PMID:32135011
RETrace: simultaneous retrospective lineage tracing and methylation profiling of single cells. PMID:32127417
Dnmt3a and Dnmt3b-Decommissioned Fetal Enhancers are Linked to Kidney Disease. PMID:32127410
Does DNA Methylation Matter in FSHD? PMID:32121044
Transgene-mediated skeletal phenotypic variation in zebrafish. PMID:32112658
Integrated Mobile Element Scanning (ME-Scan) method for identifying multiple types of polymorphic mobile element insertions. PMID:32110248
Mutational Load and the Functional Fraction of the Human Genome. PMID:32108234
Data libraries - the missing element for modeling biological systems. PMID:32100391
Precision health: A nursing perspective. PMID:32099853
Villains or heroes? The raison d'être of viruses. PMID:32099651
Micro RNA Molecules as Modulators of Treatment Resistance, Immune Checkpoints Controllers and Sensitive Biomarkers in Glioblastoma Multiforme. PMID:32098401
Role of Non-Coding RNAs in the Development of Targeted Therapy and Immunotherapy Approaches for Chronic Lymphocytic Leukemia. PMID:32098192
Finding and extending ancient simple sequence repeat-derived regions in the human genome. PMID:32095164
Systematic identification of silencers in human cells. PMID:32094911
Awakening the dark side: retrotransposon activation in neurodegenerative disorders. PMID:32092528
A guide to naming human non-coding RNA genes. PMID:32090359
Minireview on the Relations between Gut Microflora and Parkinson's Disease: Further Biochemical (Oxidative Stress), Inflammatory, and Neurological Particularities. PMID:32089768
Insertion of LINE-1 Retrotransposon Inducing Exon Inversion Causes a Rotor Syndrome Phenotype. PMID:32082363
Brain Cytoplasmic RNAs in Neurons: From Biosynthesis to Function. PMID:32079202
Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated by Cis Noncoding Mutations. PMID:32078798
Decoding a highly mixed Kazakh genome. PMID:32076829
Short interspersed nuclear element (SINE)-mediated post-transcriptional effects on human and mouse gene expression: SINE-UP for active duty. PMID:32075563
sRNA/L1 retrotransposition: using siRNAs and miRNAs to expand the applications of the cell culture-based LINE-1 retrotransposition assay. PMID:32075559
An atlas of transposable element-derived alternative splicing in cancer. PMID:32075558
Human transposon insertion profiling by sequencing (TIPseq) to map LINE-1 insertions in single cells. PMID:32075555
Widespread correlation of KRAB zinc finger protein binding with brain-developmental gene expression patterns. PMID:32075554
Transposable elements have contributed human regulatory regions that are activated upon bacterial infection. PMID:32075553
BlobToolKit - Interactive Quality Assessment of Genome Assemblies. PMID:32071071
Traveler, a New DD35E Family of Tc1/Mariner Transposons, Invaded Vertebrates Very Recently. PMID:32068835
Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines. PMID:32055257
What animals can teach us about evolution, the human genome, and human disease. PMID:32054372
Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection. PMID:32053593
Poly-Enrich: count-based methods for gene set enrichment testing with genomic regions. PMID:32051932
The draft genome of mandrill (Mandrillus sphinx): An Old World monkey. PMID:32051450
Re-recognition of pseudogenes: From molecular to clinical applications. PMID:32042317
Tissue and cancer-specific expression of DIEXF is epigenetically mediated by an Alu repeat. PMID:32041475
Artificial Intelligence for Cardiac Imaging-Genetics Research. PMID:32039240
Studies on the Small Body Size Mouse Developed by Mutagen N-Ethyl-N-nitrosourea. PMID:32038779
Pan-genomics in the human genome era. PMID:32034321
Human Long Noncoding RNA Interactome: Detection, Characterization and Function. PMID:32033158
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. PMID:32024998
Genetic tests by next-generation sequencing in children with developmental delay and/or intellectual disability. PMID:32024334
Prediction of short-term neonatal complications in preterm infants using exome-wide genetic variation and gestational age: a pilot study. PMID:32023625
Precise hepatectomy in the intelligent digital era. PMID:32015674
Unveiling ncRNA regulatory axes in atherosclerosis progression. PMID:32009226
ATAC-Me Captures Prolonged DNA Methylation of Dynamic Chromatin Accessibility Loci during Cell Fate Transitions. PMID:31999955
A New Weighted Imputed Neighborhood-Regularized Tri-Factorization One-Class Collaborative Filtering Algorithm: Application to Target Gene Prediction of Transcription Factors. PMID:31995498
Towards a comprehensive catalogue of validated and target-linked human enhancers. PMID:31988385
Tetranucleotide Microsatellite Mutational Behavior Assessed in Real Time: Implications for Future Microsatellite Panels. PMID:31982570
Aberrantly High Levels of Somatic LINE-1 Expression and Retrotransposition in Human Neurological Disorders. PMID:31969897
Worldwide carrier frequency and genetic prevalence of autosomal recessive inherited retinal diseases. PMID:31964843
A potential new mechanism for pregnancy loss: considering the role of LINE-1 retrotransposons in early spontaneous miscarriage. PMID:31964400
MicroRNAs in Vascular Eye Diseases. PMID:31963809
In-Depth Mapping of the Urinary N-Glycoproteome: Distinct Signatures of ccRCC-related Progression. PMID:31963743
Idiopathic Pulmonary Fibrosis: Pathogenesis and the Emerging Role of Long Non-Coding RNAs. PMID:31947693
The Missing "lnc" between Genetics and Cardiac Disease. PMID:31947625
The Developmental Gene Hypothesis for Punctuated Equilibrium: Combined Roles of Developmental Regulatory Genes and Transposable Elements. PMID:31943266
A draft genome sequence of the elusive giant squid, Architeuthis dux. PMID:31942620
Compensating for over-production inhibition of the Hsmar1 transposon in Escherichia coli using a series of constitutive promoters. PMID:31938044
PP2A Phosphatases Take a Giant Leap in the Post-Genomics Era. PMID:31929724
Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability. PMID:31929557
How technical progress reshaped behavioral neuroendocrinology during the last 50 years… and some methodological remarks. PMID:31927020
Comparative analysis on the expression of L1 loci using various RNA-Seq preparations. PMID:31921361
A brief history of human disease genetics. PMID:31915397
The p53 family reaches the final frontier: the variegated regulation of the dark matter of the genome by the p53 family in cancer. PMID:31910062
Unzipping haplotypes in diploid and polyploid genomes. PMID:31908732
Structural variant identification and characterization. PMID:31907725
The SUMO Ligase Su(var)2-10 Controls Hetero- and Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation. PMID:31901448
Alpha-hemoglobin-stabilizing protein (AHSP): a modulatory factor in β-thalassemia. PMID:31894534
LINE-1 ORF2p expression is nearly imperceptible in human cancers. PMID:31892958
Targeted viral vector transduction of relaxin-3 neurons in the rat nucleus incertus using a novel cell-type specific promoter. PMID:31890981
Long walk to genomics: History and current approaches to genome sequencing and assembly. PMID:31890139
A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells. PMID:31890047
Few SINEs of life: Alu elements have little evidence for biological relevance despite elevated translation. PMID:31886458
Immunotherapy and next-generation sequencing guided therapy for precision oncology: What have we learnt and what does the future hold? PMID:31886407
B2 and ALU retrotransposons are self-cleaving ribozymes whose activity is enhanced by EZH2. PMID:31871160
Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression. PMID:31870430
A network embedding model for pathogenic genes prediction by multi-path random walking on heterogeneous network. PMID:31865919
A unified STR profiling system across multiple species with whole genome sequencing data. PMID:31861983
Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes. PMID:31860668
Nucleotide composition of transposable elements likely contributes to AT/GC compositional homogeneity of teleost fish genomes. PMID:31857829
Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology. PMID:31853540
Novel human sex-typing strategies based on the autism candidate gene NLGN4X and its male-specific gametologue NLGN4Y. PMID:31852540
Long non-coding RNAs in ovarian cancer: expression profile and functional spectrum. PMID:31847695
Application of DArT seq derived SNP tags for comparative genome analysis in fishes; An alternative pipeline using sequence data from a non-traditional model species, Macquaria ambigua. PMID:31830141
A primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in humans. PMID:31827084
Arteria: An automation system for a sequencing core facility. PMID:31825479
TEffectR: an R package for studying the potential effects of transposable elements on gene expression with linear regression model. PMID:31824778
Targeted deep-intronic sequencing in a cohort of unexplained cases of suspected Lynch syndrome. PMID:31822864
Glyoxalase 1 gene improves the antistress capacity and reduces the immune inflammatory response. PMID:31822263
Evolutionary Forces and Codon Bias in Different Flavors of Intrinsic Disorder in the Human Proteome. PMID:31820049
Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians. PMID:31817660
Conversion of DNA Sequences: From a Transposable Element to a Tandem Repeat or to a Gene. PMID:31817529
Pharmacogenomics In Pharmacy Practice: Current Perspectives. PMID:31807435
Recapitulation-like developmental transitions of chromatin accessibility in vertebrates. PMID:31807314
Endogenous Retroviruses Activity as a Molecular Signature of Neurodevelopmental Disorders. PMID:31801288
Artificial intelligence for precision medicine in neurodevelopmental disorders. PMID:31799421
Endogenous retroviruses are associated with hippocampus-based memory impairment. PMID:31792184
High-throughput long paired-end sequencing of a Fosmid library by PacBio. PMID:31788019
The Role of SINE-VNTR-Alu (SVA) Retrotransposons in Shaping the Human Genome. PMID:31783611
Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis. PMID:31782165
Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization. PMID:31777926
GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs. PMID:31776332
TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation. PMID:31759822
Integrative genetic map of repetitive DNA in the sole Solea senegalensis genome shows a Rex transposon located in a proto-sex chromosome. PMID:31748593
Role of Molecular Profiling of Pancreatic Cancer After Neoadjuvant Therapy: Does it Change Practice? PMID:31745905
Snapshots of a genetic cut-and-paste. PMID:31745352
Transposable element expression in tumors is associated with immune infiltration and increased antigenicity. PMID:31745090
The Human Immunopeptidome Project: A Roadmap to Predict and Treat Immune Diseases. PMID:31744855
Comparative genomic analysis of eutherian connexin genes. PMID:31729432
Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist. PMID:31729316
[Mass spectrometry-applications in pathology]. PMID:31713660
New developments on the Encyclopedia of DNA Elements (ENCODE) data portal. PMID:31713622
Synthetic lethality as an engine for cancer drug target discovery. PMID:31712683
X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications. PMID:31711961
Genetics of Childhood-onset Schizophrenia 2019 Update. PMID:31708045
Dynamic DNA Energy Landscapes and Substrate Complexity in Triplet Repeat Expansion and DNA Repair. PMID:31698848
Nature at 150: evidence in pursuit of truth. PMID:31695220
Ensembl 2020. PMID:31691826
A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation. PMID:31691800
The Concomitant Expression of Human Endogenous Retroviruses and Embryonic Genes in Cancer Cells under Microenvironmental Changes is a Potential Target for Antiretroviral Drugs. PMID:31691184
Recurrent intragenic exon rearrangements of SOBP and AUTS2 in non-Hodgkin B-cell lymphoma. PMID:31686349
Roles of Topoisomerases in Heterochromatin, Aging, and Diseases. PMID:31683993
Differential regulatory network-based quantification and prioritization of key genes underlying cancer drug resistance based on time-course RNA-seq data. PMID:31682596
Widespread sex dimorphism in aging and age-related diseases. PMID:31677133
The Many Faces of Gene Regulation in Cancer: A Computational Oncogenomics Outlook. PMID:31671657
Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level. PMID:31671630
Protein Structural Information and Evolutionary Landscape by In Vitro Evolution. PMID:31670785
Comprehensive Scanning Mutagenesis of Human Retrotransposon LINE-1 Identifies Motifs Essential for Function. PMID:31666291
A 96-multiplex capillary electrophoresis screening platform for product based evolution of P450 BM3. PMID:31664146
Human-specific tandem repeat expansion and differential gene expression during primate evolution. PMID:31659027
Molecular determinants of drug response in TNBC cell lines. PMID:31655920
Comparative Genomics Analysis Reveals High Levels of Differential Retrotransposition among Primates from the Hominidae and the Cercopithecidae Families. PMID:31651947
Deep Learning Enables Accurate Prediction of Interplay Between lncRNA and Disease. PMID:31649723
Retrotransposons spread potential cis-regulatory elements during mammary gland evolution. PMID:31642473
DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma. PMID:31639042
Evolutionary history and classification of Micropia retroelements in Drosophilidae species. PMID:31622354
Recovery of non-reference sequences missing from the human reference genome. PMID:31619167
Five months of voluntary wheel running downregulates skeletal muscle LINE-1 gene expression in rats. PMID:31618076
Children With Autism Spectrum Disorder and Their Mothers Share Abnormal Expression of Selected Endogenous Retroviruses Families and Cytokines. PMID:31616420
Specification of the First Mammalian Cell Lineages In Vivo and In Vitro. PMID:31615786
Changing expression profiles of lncRNAs, circRNAs and mRNAs in esophageal squamous carcinoma. PMID:31612046
A Japanese history of the Human Genome Project. PMID:31611500
Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development. PMID:31608120
Introducing the first whole genomes of nationals from the United Arab Emirates. PMID:31604968
On the Function of Trans-Splicing: No Evidence for Widespread Proteome Diversification in Trypanosomes. PMID:31599940
Evaluating Chromatin Accessibility Differences Across Multiple Primate Species Using a Joint Modeling Approach. PMID:31599933
Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0. PMID:31599596
Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology. PMID:31597351
Co-Localization of DNA i-Motif-Forming Sequences and 5-Hydroxymethyl-cytosines in Human Embryonic Stem Cells. PMID:31597270
Lung genotoxicity of benzo(a)pyrene in vivo involves reactivation of LINE-1 retrotransposon and early reprogramming of oncogenic regulatory networks. PMID:31596105
Functional Genomics of the Retina to Elucidate its Construction and Deconstruction. PMID:31590277
Reporting on the future of integrative structural biology ORAU workshop. PMID:31585877
Synonymous genome recoding: a tool to explore microbial biology and new therapeutic strategies. PMID:31584076
Unraveling the Heterogeneous Mutational Signature of Spontaneously Developing Tumors in MLH1-/- Mice. PMID:31581674
Break-induced replication plays a prominent role in long-range repeat-mediated deletion. PMID:31571254
Up-regulation of ZFAS1 indicates dismal prognosis for cholangiocarcinoma and promotes proliferation and metastasis by modulating USF1 via miR-296-5p. PMID:31565837
Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits. PMID:31564431
Discovery of Novel Sequences in 1,000 Swedish Genomes. PMID:31560401
Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation. PMID:31549960
RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA. PMID:31548405
RNA-seq as a tool for evaluating human embryo competence. PMID:31548358
Dual-Specific Protein and Lipid Phosphatase PTEN and Its Biological Functions. PMID:31548229
Chromosomal rearrangements as a source of new gene formation in Drosophila yakuba. PMID:31545792
Chromosome-level assembly of the mustache toad genome using third-generation DNA sequencing and Hi-C analysis. PMID:31544214
Discovery of high-confidence human protein-coding genes and exons by whole-genome PhyloCSF helps elucidate 118 GWAS loci. PMID:31537640
LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly. PMID:31537638
Xist RNA in action: Past, present, and future. PMID:31537017
Tracking the Fate of Endogenous Retrovirus Segregation in Wild and Domestic Cats. PMID:31534037
Overlapping protein-coding genes in human genome and their coincidental expression in tissues. PMID:31527706
The first enhancer in an enhancer chain safeguards subsequent enhancer-promoter contacts from a distance. PMID:31514731
SKF-LDA: Similarity Kernel Fusion for Predicting lncRNA-Disease Association. PMID:31514111
Quantitative detection of ALK fusion breakpoints in plasma cell-free DNA from patients with non-small cell lung cancer using PCR-based target sequencing with a tiling primer set and two-step mapping/alignment. PMID:31513617
Mechanisms of nuclear mRNA export: A structural perspective. PMID:31513326
Current Trends in Applications of Circulatory Microchimerism Detection in Transplantation. PMID:31509957
The Evolving Field of Genetic Epidemiology: From Familial Aggregation to Genomic Sequencing. PMID:31509181
Socioeconomic status and DNA methylation from birth through mid-childhood: a prospective study in Project Viva. PMID:31509016
5-Azacytidine modulates CpG methylation levels of EZH2 and NOTCH1 in myelodysplastic syndromes. PMID:31506740
SNV identification from single-cell RNA sequencing data. PMID:31504520
Detection of Microsatellite Instability Biomarkers via Next-Generation Sequencing. PMID:31502149
The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium. PMID:31501771
Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome. PMID:31494266
Functional disease architectures reveal unique biological role of transposable elements. PMID:31492842
Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival. PMID:31492840
A novel evolutionary model for constructing gene coexpression networks with comprehensive features. PMID:31492104
H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks. PMID:31491936
Food Safety and Nutraceutical Potential of Caramel Colour Class IV Using In Vivo and In Vitro Assays. PMID:31491925
Expanding the scope and scale of microbiome research. PMID:31488207
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination. PMID:31486214
Clinical value of non-coding RNAs in cardiovascular, pulmonary, and muscle diseases. PMID:31483703
Transposable Elements, Inflammation, and Neurological Disease. PMID:31481926
Discovering human transcription factor physical interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays. PMID:31481462
The Length of the Expressed 3' UTR Is an Intermediate Molecular Phenotype Linking Genetic Variants to Complex Diseases. PMID:31475030
Dynamical Electrical Complexity Is Reduced during Neuronal Differentiation in Autism Spectrum Disorder. PMID:31474529
Accumulation of Circulating Cell-Free CpG-Enriched Ribosomal DNA Fragments on the Background of High Endonuclease Activity of Blood Plasma in Schizophrenic Patients. PMID:31467866
Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine. PMID:31462645
A concise review of human brain methylome during aging and neurodegenerative diseases. PMID:31462381
β-mercaptoethanol assists efficient construction of sperm bacterial artificial chromosome library. PMID:31453223
Intrauterine programming of obesity and type 2 diabetes. PMID:31451874
Chromosomics: Bridging the Gap between Genomes and Chromosomes. PMID:31434289
The lncRNA Malat1 functions as a ceRNA to contribute to berberine-mediated inhibition of HMGB1 by sponging miR-181c-5p in poststroke inflammation. PMID:31431734
Identification of mutations in HEXA and HEXB in Sandhoff and Tay-Sachs diseases: a new large deletion caused by Alu elements in HEXA. PMID:31428437
Investigation of NF-κB-94ins/del ATTG and CARD8 (rs2043211) Gene Polymorphism in Acute Lymphoblastic Leukemia. PMID:31428046
TeXP: Deconvolving the effects of pervasive and autonomous transcription of transposable elements. PMID:31425522
Transposable element-mediated structural variation analysis in dog breeds using whole-genome sequencing. PMID:31414176
Genome-wide analysis of polymerase III-transcribed Alu elements suggests cell-type-specific enhancer function. PMID:31413151
Increased HERV-E clone 4-1 expression contributes to DNA hypomethylation and IL-17 release from CD4+ T cells via miR-302d/MBD2 in systemic lupus erythematosus. PMID:31412880
Biophysics and the Genomic Sciences. PMID:31409480
A Long Polymorphic GT Microsatellite within a Gene Promoter Mediates Non-Imprinted Allele-Specific DNA Methylation of a CpG Island in a Goldfish Inter-Strain Hybrid. PMID:31409051
Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome. PMID:31406327
ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity. PMID:31404141
Is it time to change the reference genome? PMID:31399121
Dietary Patterns are Associated with Leukocyte LINE-1 Methylation in Women: A Cross-Sectional Study in Southern Italy. PMID:31395820
A Genome Model to Explain Major Features of Neurodevelopmental Disorders in Newborns. PMID:31391780
ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion. PMID:31391455
Correlation of long interspersed element-1 open reading frame 1 and c-Met proto-oncogene protein expression in ovarian cancer. PMID:31388980
Transmissible Cancers and Immune Downregulation in Tasmanian Devil (Sacrophilus harrisii) and Canine Populations. PMID:31387668
Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype. PMID:31375807
Patterns of conservation of spliceosomal intron structures and spliceosome divergence in representatives of the diplomonad and parabasalid lineages. PMID:31375061
Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease. PMID:31372185
Rare and common variant discovery in complex disease: the IBD case study. PMID:31363759
Endogenous Retrovirus-Derived Long Noncoding RNA Enhances Innate Immune Responses via Derepressing RELA Expression. PMID:31363026
Microsatellite Marker Analysis for Laboratory Mice Profiling. PMID:31360681
AluMine: alignment-free method for the discovery of polymorphic Alu element insertions. PMID:31360240
FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue. PMID:31352405
High Prevalence and Disease Correlation of Autoantibodies Against p40 Encoded by Long Interspersed Nuclear Elements in Systemic Lupus Erythematosus. PMID:31342656
Human APOBEC3G Prevents Emergence of Infectious Endogenous Retrovirus in Mice. PMID:31341050
Heterogeneous transposable elements as silencers, enhancers and targets of meiotic recombination. PMID:31332531
Non-cell autonomous mechanism of Parkinson's disease pathology caused by G2019S LRRK2 mutation in Ashkenazi Jewish patient: Single cell analysis. PMID:31330122
Repeat-associated RNA structure and aberrant splicing. PMID:31323433
Identifying causal variants and genes using functional genomics in specialized cell types and contexts. PMID:31317254
An Evaluation of Machine Learning Approaches for the Prediction of Essential Genes in Eukaryotes Using Protein Sequence-Derived Features. PMID:31312416
GC content of vertebrate exome landscapes reveal areas of accelerated protein evolution. PMID:31311498
Fast and accurate medication identification. PMID:31304359
Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis. PMID:31303496
Non-Coding RNAs and their Integrated Networks. PMID:31301674
Discovery of receptor-ligand interfaces in the immunoglobulin superfamily. PMID:31298437
Transposable Elements and Their Epigenetic Regulation in Mental Disorders: Current Evidence in the Field. PMID:31293617
Identifying, understanding, and correcting technical artifacts on the sex chromosomes in next-generation sequencing data. PMID:31289836
Alu RNA Modulates the Expression of Cell Cycle Genes in Human Fibroblasts. PMID:31284509
Brain organoids and insights on human evolution. PMID:31275562
Mode and Tempo of Microsatellite Length Change in a Malaria Parasite Mutation Accumulation Experiment. PMID:31273388
Genetic Variation, Comparative Genomics, and the Diagnosis of Disease. PMID:31269367
Dynamic expression of tRNA-derived small RNAs define cellular states. PMID:31267708
Centralized scientific communities are less likely to generate replicable results. PMID:31264964
LLCLPLDA: a novel model for predicting lncRNA-disease associations. PMID:31250107
Molecular Mechanisms and Determinants of Innovative Correction Approaches in Coagulation Factor Deficiencies. PMID:31234407
Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing. PMID:31231536
New pathologic mechanisms in nucleotide repeat expansion disorders. PMID:31229686
SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina. PMID:31226208
The role of hydrophobic matching on transmembrane helix packing in cells. PMID:31225439
Exome Sequencing in Clinical Hepatology. PMID:31222768
Expression of GCRG213p, LINE-1 endonuclease variant, significantly different in gastric complete and incomplete intestinal metaplasia. PMID:31221180
Simultaneous TE Analysis of 19 Heliconiine Butterflies Yields Novel Insights into Rapid TE-Based Genome Diversification and Multiple SINE Births and Deaths. PMID:31214686
RNA-protein interactions: disorder, moonlighting and junk contribute to eukaryotic complexity. PMID:31213136
Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver. PMID:31204013
The Hunt for Degrons of the 26S Proteasome. PMID:31200568
Identification of a Retroelement-Containing Human Transcript Induced in the Nucleus by Vaccination. PMID:31200438
Using phenome-wide association studies to examine the effect of environmental exposures on human health. PMID:31200158
Early life exposures, neurodevelopmental disorders, and transposable elements. PMID:31193573
Patterns in the genome. PMID:31189906
Genome sequencing-the dawn of a game-changing era. PMID:31189904
The Potential Role of Genomic Medicine in the Therapeutic Management of Rheumatoid Arthritis. PMID:31185701
Jérôme Lejeune passed away 25 years ago. PMID:31182939
CFIm25 and alternative polyadenylation: Conflicting roles in cancer. PMID:31181319
Novel de novo frameshift variant in the ASXL3 gene in a child with microcephaly and global developmental delay. PMID:31180560
Mechanisms of genome evolution in Candida albicans. PMID:31176092
Translational Metabolomics: Current Challenges and Future Opportunities. PMID:31174372
First Responder to Genomic Information: A Guide for Primary Care Providers. PMID:31172371
Characterization of bovine (Bos taurus) imprinted genes from genomic to amino acid attributes by data mining approaches. PMID:31170205
Misassembly of long reads undermines de novo-assembled ethnicity-specific genomes: validation in a Chinese Han population. PMID:31168775
Modern technologies and algorithms for scaffolding assembled genomes. PMID:31166948
WashU Epigenome Browser update 2019. PMID:31165883
Human protein-coding genes and gene feature statistics in 2019. PMID:31164174
Negative regulation of miR-1275 by H3K27me3 is critical for glial induction of glioblastoma cells. PMID:31162799
Emerging roles of histone modifications and HDACs in RNA splicing. PMID:31162605
LtrDetector: A tool-suite for detecting long terminal repeat retrotransposons de-novo. PMID:31159720
RNA Next-Generation Sequencing and a Bioinformatics Pipeline to Identify Expressed LINE-1s at the Locus-Specific Level. PMID:31157783
The Potential for microRNA Therapeutics and Clinical Research. PMID:31156715
Variable Baseline Papio cynocephalus Endogenous Retrovirus (PcEV) Expression Is Upregulated in Acutely SIV-Infected Macaques and Correlated to STAT1 Expression in the Spleen. PMID:31156613
ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures. PMID:31153042
Expression dynamics of repetitive DNA in early human embryonic development. PMID:31151386
Health Disparities and Sepsis: a Systematic Review and Meta-Analysis on the Influence of Race on Sepsis-Related Mortality. PMID:31144133
Genomics and data science: an application within an umbrella. PMID:31142351
The Structural and Functional Diversity of Intrinsically Disordered Regions in Transmembrane Proteins. PMID:31139867
Tracing the history of LINE and SINE extinction in sigmodontine rodents. PMID:31139266
Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation. PMID:31135340
Long noncoding-RNA component of mitochondrial RNA processing endoribonuclease is involved in the progression of cholangiocarcinoma by regulating microRNA-217. PMID:31111617
Population genetic data of 20 insertion-null allele markers in the Andalusian population. PMID:31111220
An ATAC-seq atlas of chromatin accessibility in mouse tissues. PMID:31110271
MERMAID: dedicated web server to prepare and run coarse-grained membrane protein dynamics. PMID:31106328
Molecular pattern of lncRNAs in hepatocellular carcinoma. PMID:31097003
Determination and analysis of agonist and antagonist potential of naturally occurring flavonoids for estrogen receptor (ERα) by various parameters and molecular modelling approach. PMID:31092862
c-Myc induced the regulation of long non-coding RNA RHPN1-AS1 on breast cancer cell proliferation via inhibiting P53. PMID:31089812
In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival. PMID:31089191
ULTRA: A Model Based Tool to Detect Tandem Repeats. PMID:31080962
Retrotransposons evolution and impact on lncRNA and protein coding genes in pigs. PMID:31080521
Recognition of 3'-end L1, Alu, processed pseudogenes, and mRNA stem-loops in the human genome using sequence-based and structure-based machine-learning models. PMID:31076573
Centromeric Satellite DNAs: Hidden Sequence Variation in the Human Population. PMID:31072070
De novo emergence and potential function of human-specific tandem repeats in brain-related loci. PMID:31069507
Humans and Chimpanzees Display Opposite Patterns of Diversity in Arylamine N-Acetyltransferase Genes. PMID:31068377
Composite Analysis of the Virome and Bacteriome of HIV/HPV Co-Infected Women Reveals Proxies for Immunodeficiency. PMID:31067713
Diversification of Transposable Elements in Arthropods and Its Impact on Genome Evolution. PMID:31064091
Target Gene Prediction of Transcription Factor Using a New Neighborhood-regularized Tri-factorization One-class Collaborative Filtering Algorithm. PMID:31061989
Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations. PMID:31061957
Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines. PMID:31061680
Using RNA-seq to characterize responses to 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicide resistance in waterhemp (Amaranthus tuberculatus). PMID:31060501
Birth, School, Work, Death, and Resurrection: The Life Stages and Dynamics of Transposable Element Proliferation. PMID:31058854
Systems biology in inflammatory bowel diseases: on the way to precision medicine. PMID:31040620
What viruses tell us about evolution and immunity: beyond Darwin? PMID:31032941
Dissecting Motor Neuron Disease With Drosophila melanogaster. PMID:31031583
DeePromoter: Robust Promoter Predictor Using Deep Learning. PMID:31024615
Gene Lifestyle Interactions With Relation to Obesity, Cardiometabolic, and Cardiovascular Traits Among South Asians. PMID:31024458
The impact of poly-A microsatellite heterologies in meiotic recombination. PMID:31023833
Prediction of Human Immunodeficiency Virus Type 1 Subtype-Specific Off-Target Effects Arising from CRISPR-Cas9 Gene Editing Therapy. PMID:31021222
Impact of Genetic Variation on CRISPR-Cas Targeting. PMID:31021199
Genetic Variations and Precision Medicine. PMID:31019429
Sequencing of human genomes with nanopore technology. PMID:31015479
Mouse germ line mutations due to retrotransposon insertions. PMID:31011371
miR-128 Restriction of LINE-1 (L1) Retrotransposition Is Dependent on Targeting hnRNPA1 mRNA. PMID:31010097
ChimeraMiner: An Improved Chimeric Read Detection Pipeline and Its Application in Single Cell Sequencing. PMID:31010074
Subtype classification and functional annotation of L1Md retrotransposon promoters. PMID:31007728
Genome-Wide Search for Tyrosine Phosphatases in the Human Genome Through Computational Approaches Leads to the Discovery of Few New Domain Architectures. PMID:31007525
Long Noncoding RNA and Epithelial Mesenchymal Transition in Cancer. PMID:31003545
Whole Genome Sequencing and Re-sequencing of the Sable Antelope (Hippotragus niger): A Resource for Monitoring Diversity in ex Situ and in Situ Populations. PMID:31000506
The Many Faces of EpigeneticsOxford, December 2017. PMID:30994386
Protein Structure-Guided Hidden Markov Models (HMMs) as A Powerful Method in the Detection of Ancestral Endogenous Viral Elements. PMID:30986983
HERVs, immunity, and autoimmunity: understanding the connection. PMID:30984482
Evidence for ligandable sites in structured RNA throughout the Protein Data Bank. PMID:30982658
Large-scale 3D chromatin reconstruction from chromosomal contacts. PMID:30967119
A secure SNP panel scheme using homomorphically encrypted K-mers without SNP calling on the user side. PMID:30967116
Small molecule targeting of RNA structures in neurological disorders. PMID:30964958
Genetic and epigenetic sex-specific adaptations to endurance exercise. PMID:30957644
Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication. PMID:30955886
Detailed methylation map of LINE-1 5'-promoter region reveals hypomethylated CpG hotspots associated with tumor tissue specificity. PMID:30955237
One hundred years of Drosophila cancer research: no longer in solitude. PMID:30952627
A Pipeline for Faecal Host DNA Analysis by Absolute Quantification of LINE-1 and Mitochondrial Genomic Elements Using ddPCR. PMID:30944341
Mendelian Inconsistent Signatures from 1314 Ancestrally Diverse Family Trios Distinguish Biological Variation from Sequencing Error. PMID:30942611
Viruses and Evolution - Viruses First? A Personal Perspective. PMID:30941110
Regulatory Non-coding RNAs Network in Non-alcoholic Fatty Liver Disease. PMID:30941061
Discovery of Teneurins. PMID:30941006
On the Importance to Acknowledge Transposable Elements in Epigenomic Analyses. PMID:30935103
Investigation of somatic single nucleotide variations in human endogenous retrovirus elements and their potential association with cancer. PMID:30934003
BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV. PMID:30926617
The Genome and mRNA Transcriptome of the Cosmopolitan Calanoid Copepod Acartia tonsa Dana Improve the Understanding of Copepod Genome Size Evolution. PMID:30918947
Overlooked: Extrachromosomal DNA and Their Possible Impact on Whole Genome Sequencing. PMID:30918452
Does the Presence of Transposable Elements Impact the Epigenetic Environment of Human Duplicated Genes? PMID:30917603
GenomeWarp: an alignment-based variant coordinate transformation. PMID:30916319
Repeat-Associated Non-ATG Translation: Molecular Mechanisms and Contribution to Neurological Disease. PMID:30909783
SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells. PMID:30902974
Functional roles of the human ribonuclease A superfamily in RNA metabolism and membrane receptor biology. PMID:30902663
Nutrigenomics of Vitamin D. PMID:30901909
The impact of transposable element activity on therapeutically relevant human stem cells. PMID:30899334
Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome. PMID:30899333
Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European National Reference Center: Neisseria meningitidis as a Proof-of-Concept. PMID:30894839
Predicting mutations deleterious to function in beta-lactamase TEM1 using MM-GBSA. PMID:30889230
Amplification Dynamics of Platy-1 Retrotransposons in the Cebidae Platyrrhine Lineage. PMID:30888417
Primate piRNA Cluster Evolution Suggests Limited Relevance of Pseudogenes in piRNA-Mediated Gene Regulation. PMID:30888404
Long Noncoding RNA and Protein Interactions: From Experimental Results to Computational Models Based on Network Methods. PMID:30875752
Glass confers rhabdomeric photoreceptor identity in Drosophila, but not across all metazoans. PMID:30873275
Similarities and differences between variants called with human reference genome HG19 or HG38. PMID:30871461
Synthetic Lethality in Lung Cancer-From the Perspective of Cancer Genomics. PMID:30871030
Increased Transfection of the Easily Oxidizable GC-Rich DNA Fragments into the MCF7 Breast Cancer Cell. PMID:30867888
A comparative survey of microsatellites among wild and domestic cat provides valuable resources for marker development. PMID:30864111
KMT1 family methyltransferases regulate heterochromatin-nuclear periphery tethering via histone and non-histone protein methylation. PMID:30858340
Translating Pharmacogenetics and Pharmacogenomics to the Clinic: Progress in Human and Veterinary Medicine. PMID:30854372
Recent Progress of Polymeric Nanogels for Gene Delivery. PMID:30853837
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. PMID:30853213
DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development. PMID:30850438
2018 William Allan Award: Discovering the Genes for Common Disease: From Families to Populations. PMID:30849323
A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families. PMID:30845214
Potential Implications of Long Noncoding RNAs in Autoimmune Diseases. PMID:30838159
From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products. PMID:30838017
Tropomyosins: Potential Biomarkers for Urothelial Bladder Cancer. PMID:30836651
Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis. PMID:30826177
Mapping the dsRNA World. PMID:30824577
Epigenetic changes during aging and their reprogramming potential. PMID:30822165
Common workflow language (CWL)-based software pipeline for de novo genome assembly from long- and short-read data. PMID:30821816
Metabolic therapies inhibit tumor growth in vivo and in silico. PMID:30816152
On the length, weight and GC content of the human genome. PMID:30813969
Insights into DNA polymerase δ's mechanism for accurate DNA replication. PMID:30810803
In-depth structural analysis of glycans in the gas phase. PMID:30809341
Circular RNAs in immune responses and immune diseases. PMID:30809295
Logic Regression Analysis of Gene Polymorphisms and HDL Levels in a Nationally Representative Sample of Iranian Adolescents: The CASPIAN-III Study. PMID:30805016
Discrimination Between Self and Non-Self-Nucleic Acids by the Innate Immune System. PMID:30798985
Cohort profile: design and methods in the eye and vision consortium of UK Biobank. PMID:30796124
Completing the genetic spectrum influencing coronary artery disease: from germline to somatic variation. PMID:30789660
Prostate-specific loss of UXT promotes cancer progression. PMID:30774773
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects. PMID:30770445
Endogenous Retroviruses Function as Gene Expression Regulatory Elements During Mammalian Pre-implantation Embryo Development. PMID:30759824
[Breakthrough in understanding the molecular causes of psychiatric disorders]. PMID:30758637
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. PMID:30739867
Retroelement-Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution. PMID:30736359
Precision epidemiology for infectious disease control. PMID:30728537
Estimation of duplication history under a stochastic model for tandem repeats. PMID:30727948
Inferring pathogen-host interactions between Leptospira interrogans and Homo sapiens using network theory. PMID:30723266
Profiling of LINE-1-Related Genes in Hepatocellular Carcinoma. PMID:30717368
Deficiency of the Fanconi anemia E2 ubiqitin conjugase UBE2T only partially abrogates Alu-mediated recombination in a new model of homology dependent recombination. PMID:30715513
The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV. PMID:30709743
Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells. PMID:30707417
Novel Discovery of LINE-1 in a Korean Individual by a Target Enrichment Method. PMID:30699287
Dynamic Methylation of an L1 Transduction Family during Reprogramming and Neurodifferentiation. PMID:30692270
ensembldb: an R package to create and use Ensembl-based annotation resources. PMID:30689724
Whole genome sequencing of breast cancer. PMID:30689231
A re-annotation of the Anopheles darlingi mobilome. PMID:30672977
Where is genomics going next? PMID:30670080
Characterizing the Major Structural Variant Alleles of the Human Genome. PMID:30661756
Mouse PVRIG Has CD8+ T Cell-Specific Coinhibitory Functions and Dampens Antitumor Immunity. PMID:30659055
Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors. PMID:30655558
Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription. PMID:30652128
Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals. PMID:30646609
SQuIRE reveals locus-specific regulation of interspersed repeat expression. PMID:30624635
Growth factor signalling in osteoarthritis. PMID:30624091
Regulation of LINE-1 Elements by miR-128 Is Not Conserved in Mouse Embryonic Stem Cells. PMID:30619491
Single-Cell Applications of Next-Generation Sequencing. PMID:30617056
Expressional activation and functional roles of human endogenous retroviruses in cancers. PMID:30614117
Revealing the alternative promoter usage of SAF/MAZ gene by bichromatic fluorescent reporter construct. PMID:30610159
Frozen-hydrated chromatin from metaphase chromosomes has an interdigitated multilayer structure. PMID:30609992
Transcription of human endogenous retroviruses in human brain by RNA-seq analysis. PMID:30605476
A Novel Approach Based on a Weighted Interactive Network to Predict Associations of MiRNAs and Diseases. PMID:30597923
Prolonged neuromuscular block associated with cholinesterase deficiency. PMID:30593143
The ACCOuNT Consortium: A Model for the Discovery, Translation, and Implementation of Precision Medicine in African Americans. PMID:30592548
BC200 RNA: An Emerging Therapeutic Target and Diagnostic Marker for Human Cancer. PMID:30590906
Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers. PMID:30588513
Next-generation sequencing of circulating tumor DNA for detection of gene mutations in lung cancer: implications for precision treatment. PMID:30588023
Non-Coding RNAs in Glioma. PMID:30583549
RGAAT: A Reference-based Genome Assembly and Annotation Tool for New Genomes and Upgrade of Known Genomes. PMID:30583062
LINE-1 and EPAS1 DNA methylation associations with high-altitude exposure. PMID:30574831
Variation in proviral content among human genomes mediated by LTR recombination. PMID:30568734
Accounting for heteroscedasticity and censoring in chromosome partitioning analyses. PMID:30564443
Extensive and deep sequencing of the Venter/HuRef genome for developing and benchmarking genome analysis tools. PMID:30561434
Long-read sequence and assembly of segmental duplications. PMID:30559433
Prolactin-induced protein (PIP)-characterization and role in breast cancer progression. PMID:30555735
Long Interspersed Nuclear Element 1 Retrotransposons Become Deregulated during the Development of Ovarian Cancer Precursor Lesions. PMID:30553834
A hotspots analysis-relation discovery representation model for revealing diabetes mellitus and obesity. PMID:30547805
Genomic Interventions in Medicine. PMID:30546257
Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma. PMID:30546079
Repetitive Fragile Sites: Centromere Satellite DNA As a Source of Genome Instability in Human Diseases. PMID:30544645
Facial Sadness Recognition is Modulated by Estrogen Receptor Gene Polymorphisms in Healthy Females. PMID:30544539
Novel three‑lncRNA signature predicts survival in patients with pancreatic cancer. PMID:30542694
The translation of non-canonical open reading frames controls mucosal immunity. PMID:30542152
Structure, clustering and functional insights of repeats configurations in the upstream promoter region of the human coding genes. PMID:30537933
Evolution of Our Understanding of the Hyperparathyroid Syndromes: A Historical Perspective. PMID:30536424
Evolution of the Yeast Recombination Landscape. PMID:30535029
Multi-level remodeling of transcriptional landscapes in aging and longevity. PMID:30526773
Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models. PMID:30526553
Sense of Smell: Structural, Functional, Mechanistic Advancements and Challenges in Human Olfactory Research. PMID:30520376
DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation. PMID:30518531
Genomic Takeover by Transposable Elements in the Strawberry Poison Frog. PMID:30517748
Centromere-associated protein E expresses a novel mRNA isoform in acute lymphoblastic leukemia. PMID:30515258
Tracking microRNA Processing Signals by Degradome Sequencing Data Analysis. PMID:30487815
CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise. PMID:30486838
Retrotransposon insertion as a novel mutational event in Bardet-Biedl syndrome. PMID:30484961
Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine. PMID:30482208
Next-Generation Sequencing Technologies. PMID:30478097
Future Promises and Concerns of Ubiquitous Next-Generation Sequencing. PMID:30478095
Deep repeat resolution-the assembly of the Drosophila Histone Complex. PMID:30476267
Amphioxus functional genomics and the origins of vertebrate gene regulation. PMID:30464347
The importance of the Neutral Theory in 1968 and 50 years on: A response to Kern and Hahn 2018. PMID:30460993
Research progresses in roles of LncRNA and its relationships with breast cancer. PMID:30459529
Mendelian Randomization Studies Promise to Shorten the Journey to FDA Approval. PMID:30456340
Assembly of a pan-genome from deep sequencing of 910 humans of African descent. PMID:30455414
ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses. PMID:30455304
Testing the retroelement invasion hypothesis for the emergence of the ancestral eukaryotic cell. PMID:30455297
Widespread roles of enhancer-like transposable elements in cell identity and long-range genomic interactions. PMID:30455182
MiteFinderII: a novel tool to identify miniature inverted-repeat transposable elements hidden in eukaryotic genomes. PMID:30453969
PAVOOC: designing CRISPR sgRNAs using 3D protein structures and functional domain annotations. PMID:30445568
Sendai Virus Infection Induces Expression of Novel RNAs in Human Cells. PMID:30429577
Exploring the Impact of Single-Nucleotide Polymorphisms on Translation. PMID:30425729
One Major Challenge of Sequencing Large Plant Genomes Is to Know How Big They Really Are. PMID:30423889
A fast adaptive algorithm for computing whole-genome homology maps. PMID:30423094
Next-Generation Sequencing in Autism Spectrum Disorder. PMID:30420340
Ethanol and a rapid-acting antidepressant produce overlapping changes in exon expression in the synaptic transcriptome. PMID:30419244
Alu insertion variants alter mRNA splicing. PMID:30418605
Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats. PMID:30417124
Roles of Smads Family and Alternative Splicing Variants of Smad4 in Different Cancers. PMID:30410607
AFLP-AFLP in silico-NGS approach reveals polymorphisms in repetitive elements in the malignant genome. PMID:30408048
Comparative genomics of the major parasitic worms. PMID:30397333
High-complexity regions in mammalian genomes are enriched for developmental genes. PMID:30395202
The Bermuda Triangle: The Pragmatics, Policies, and Principles for Data Sharing in the History of the Human Genome Project. PMID:30390178
The influence of Neanderthal alleles on cytotoxic response. PMID:30386687
ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data. PMID:30384854
LTRs activated by Epstein-Barr virus-induced transformation of B cells alter the transcriptome. PMID:30381291
A large-scale analysis of bioinformatics code on GitHub. PMID:30379882
QTL mapping of natural variation reveals that the developmental regulator bruno reduces tolerance to P-element transposition in the Drosophila female germline. PMID:30376574
Impact of somatic and germline mutations on the outcome of systemic mastocytosis. PMID:30373888
Regulation of DNA Double-Strand Break Repair by Non-Coding RNAs. PMID:30373256
Identification of recurrent and novel mutations by whole‑genome sequencing of colorectal tumors from the Han population in Shanghai, eastern China. PMID:30365144
Atypical Parkinsonism-Dystonia Syndrome Caused by a Novel DJ1 Mutation. PMID:30363821
The Decrease in Human Endogenous Retrovirus-H Activity Runs in Parallel with Improvement in ADHD Symptoms in Patients Undergoing Methylphenidate Therapy. PMID:30360480
Transposable Elements in the Organization and Diversification of the Genome of Aegilops speltoides Tausch (Poaceae, Triticeae). PMID:30356408
LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages. PMID:30353135
A reference haplotype panel for genome-wide imputation of short tandem repeats. PMID:30353011
Prolonged Idasanutlin (RG7388) Treatment Leads to the Generation of p53-Mutated Cells. PMID:30352966
Targeted genotyping of variable number tandem repeats with adVNTR. PMID:30352806
DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements. PMID:30352618
Genome-wide map of human and mouse transcription factor binding sites aggregated from ChIP-Seq data. PMID:30352610
Antiviral resistance of stem cells. PMID:30352329
Inhibition of LINE-1 Retrotransposition by Capsaicin. PMID:30347711
De novo assembly of haplotype-resolved genomes with trio binning. PMID:30346939
Cost-effective assembly of the African wild dog (Lycaon pictus) genome using linked reads. PMID:30346553
Chromosome assembly of large and complex genomes using multiple references. PMID:30341161
Special Issue Introduction: The Wonders and Mysteries Next Generation Sequencing Technologies Help Reveal. PMID:30340386
A new approach based on targeted pooled DNA sequencing identifies novel mutations in patients with Inherited Retinal Dystrophies. PMID:30337596
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. PMID:30329085
Biased antagonism of CXCR4 avoids antagonist tolerance. PMID:30327409
Next-Generation Sequencing Strategies. PMID:30323017
Single-nucleotide variants in human RNA: RNA editing and beyond. PMID:30312373
PTB/nPTB: master regulators of neuronal fate in mammals. PMID:30310857
Colocalization analyses of genomic elements: approaches, recommendations and challenges. PMID:30307532
De Novo Assembly of Two Swedish Genomes Reveals Missing Segments from the Human GRCh38 Reference and Improves Variant Calling of Population-Scale Sequencing Data. PMID:30304863
Rapid Expansion of a Highly Germline-Expressed Mariner Element Acquired by Horizontal Transfer in the Fire Ant Genome. PMID:30304394
Crystallography and Its Impact on Carbonic Anhydrase Research. PMID:30302289
Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. PMID:30301887
The placenta goes viral: Retroviruses control gene expression in pregnancy. PMID:30300353
Combinatorial Approach for Complex Disorder Prediction: Case Study of Neurodevelopmental Disorders. PMID:30297454
Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays. PMID:30295648
ProteomeGenerator: A Framework for Comprehensive Proteomics Based on de Novo Transcriptome Assembly and High-Accuracy Peptide Mass Spectral Matching. PMID:30295032
Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition. PMID:30289389
An Analysis of IS630/Tc1/mariner Transposons in the Genome of a Pacific Oyster, Crassostrea gigas. PMID:30283979
Development of an AmpliSeqTM Panel for Next-Generation Sequencing of a Set of Genetic Predictors of Persisting Pain. PMID:30283335
Functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small-cell lung cancer. PMID:30281872
Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci. PMID:30275530
NMD-degradome sequencing reveals ribosome-bound intermediates with 3'-end non-templated nucleotides. PMID:30275517
PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma. PMID:30271949
Progress of analytical tools and techniques for human gut microbiome research. PMID:30267313
Darkness in the Human Gene and Protein Function Space: Widely Modest or Absent Illumination by the Life Science Literature and the Trend for Fewer Protein Function Discoveries Since 2000. PMID:30265449
Genomics research in Africa and its impact on global health: insights from African researchers. PMID:30263136
Multi-objective optimized genomic breeding strategies for sustainable food improvement. PMID:30262841
Non-coding RNA in Ischemic and Non-ischemic Cardiomyopathy. PMID:30259174
Epigenetic Effects of Drugs of Abuse. PMID:30257440
Noncoding RNAs as therapeutic targets in early stage diabetic kidney disease. PMID:30254844
Human Endogenous Retroviruses Are Ancient Acquired Elements Still Shaping Innate Immune Responses. PMID:30250470
Data-Driven Exploration of Selectivity and Off-Target Activities of Designated Chemical Probes. PMID:30249057
Personalised Medicine: The Odyssey from Hope to Practice. PMID:30248964
Influenza Virus-Host Co-evolution. A Predator-Prey Relationship? PMID:30245689
Genomic approaches for studying crop evolution. PMID:30241487
Prolonged DNA hydrolysis in water: A study on DNA stability. PMID:30238033
A Global Overview of Precision Medicine in Type 2 Diabetes. PMID:30237159
Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance. PMID:30236109
Genome-wide identification of tissue-specific long non-coding RNA in three farm animal species. PMID:30227846
Genomics, bio specimens, and other biological data: Current status and future directions. PMID:30226926
Association between Polymorphisms of Antioxidant Gene (MnSOD, CAT, and GPx1) and Risk of Coronary Artery Disease. PMID:30225256
Reviving a 60 million year old LINE-1 element. PMID:30221208
Repeat-associated non-ATG (RAN) translation. PMID:30213863
Functional Evolution of Avian RIG-I-Like Receptors. PMID:30213147
Somatic Mutagenesis in Mammals and Its Implications for Human Disease and Aging. PMID:30212236
Impacts of bisphenol A (BPA) and phthalate exposures on epigenetic outcomes in the human placenta. PMID:30210810
Whole genome sequencing data for two individuals of Pakistani descent. PMID:30204152
Finding Nemo's Genes: A chromosome-scale reference assembly of the genome of the orange clownfish Amphiprion percula. PMID:30203521
Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms. PMID:30202060
Transposons, p53 and Genome Security. PMID:30195581
Early Behavioral Alterations and Increased Expression of Endogenous Retroviruses Are Inherited Across Generations in Mice Prenatally Exposed to Valproic Acid. PMID:30194517
Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions. PMID:30189101
Genomes for all. PMID:30188541
Non-coding RNAs in retinal development and function. PMID:30187163
Pairs of Adjacent Conserved Noncoding Elements Separated by Conserved Genomic Distances Act as Cis-Regulatory Units. PMID:30184074
Analysis of Genome-Wide Differentiation between Native and Introduced Populations of the Cupped Oysters Crassostrea gigas and Crassostrea angulata. PMID:30184067
From Molecules to Mechanisms: Functional Proteomics and Its Application to Renal Tubule Physiology. PMID:30182799
What Are 3' UTRs Doing? PMID:30181377
The Xenopus animal cap transcriptome: building a mucociliary epithelium. PMID:30165493
Molecular functions and specific roles of circRNAs in the cardiovascular system. PMID:30159442
Circular RNAs in the cardiovascular system. PMID:30159434
Non-coding RNAs in skeletal muscle regeneration. PMID:30159421
MinION rapid sequencing: Review of potential applications in neurosurgery. PMID:30159201
Alternative splicing of the Caenorhabditis elegans lev-11 tropomyosin gene is regulated in a tissue-specific manner. PMID:30155988
Biophysical and structural characterization of the thermostable WD40 domain of a prokaryotic protein, Thermomonospora curvata PkwA. PMID:30154510
Nomenclature for endogenous retrovirus (ERV) loci. PMID:30153831
The Gut Microbiome in Adult and Pediatric Functional Gastrointestinal Disorders. PMID:30153517
Nucleic Acid-Barcoding Technologies: Converting DNA Sequencing into a Broad-Spectrum Molecular Counter. PMID:30153374
Transposable element dysregulation in systemic lupus erythematosus and regulation by histone conformation and Hsp90. PMID:30149120
Impact of non-LTR retrotransposons in the differentiation and evolution of anatomically modern humans. PMID:30147753
Bioinformatic and biological avenues for understanding alcohol use disorder. PMID:30144960
Endogenous retrovirus expression is associated with response to immune checkpoint blockade in clear cell renal cell carcinoma. PMID:30135306
The collaborative effect of scientific meetings: A study of the International Milk Genomics Consortium. PMID:30133459
Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling. PMID:30126842
Association of Bisphenol A Exposure with LINE-1 Hydroxymethylation in Human Semen. PMID:30126118
Open questions: How many genes do we have? PMID:30124169
Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection. PMID:30120595
Cross-disciplinary evolution of the genomics revolution. PMID:30116784
Application of genome analysis strategies in the clinical testing for pediatric diseases. PMID:30112248
Discovery of 7-hydroxyaporphines as conformationally restricted ligands for beta-1 and beta-2 adrenergic receptors. PMID:30108929
Proteomics: Clinical and research applications in respiratory diseases. PMID:30105802
A piRNA utilizes HILI and HIWI2 mediated pathway to down-regulate ferritin heavy chain 1 mRNA in human somatic cells. PMID:30102404
[The Use Of Pulmonary Gene Therapy In The Treatment Of Experimental Models Of Pneumonia And Septicemia]. PMID:30100668
Delineating inflammatory bowel disease through transcriptomic studies: current review of progress and evidence. PMID:30090036
Somatic mutations in the human brain: implications for psychiatric research. PMID:30087451
The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis. PMID:30087422
Gene editing in the context of an increasingly complex genome. PMID:30086710
LINE- and Alu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV. PMID:30084155
Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion. PMID:30082403
Reconstruction of the cell entry pathway of an extinct virus. PMID:30080900
Alcohol Metabolizing Polygenic Risk for Alcohol Consumption in European American College Students. PMID:30079879
Trends to store digital data in DNA: an overview. PMID:30073589
Related Endogenous Retrovirus-K Elements Harbor Distinct Protease Active Site Motifs. PMID:30072963
De novo human genome assemblies reveal spectrum of alternative haplotypes in diverse populations. PMID:30072691
Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation. PMID:30070637
Microsatellite enhancers can be targeted to impair tumorigenesis. PMID:30068701
KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control. PMID:30061100
TIP60 represses activation of endogenous retroviral elements. PMID:30053221
Mobile elements contribute to the uniqueness of human genome with 15,000 human-specific insertions and 14 Mbp sequence increase. PMID:30052927
Epigenome editing of microsatellite repeats defines tumor-specific enhancer functions and dependencies. PMID:30042132
[Genetics in medicine]. PMID:30039391
Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation. PMID:30037981
Non-Coding RNAs in Endometrial Physiopathology. PMID:30037059
Cellular Genomic Sites of Hepatitis B Virus DNA Integration. PMID:30037029
Investigation of epigenetic regulatory networks associated with autism spectrum disorder (ASD) by integrated global LINE-1 methylation and gene expression profiling analyses. PMID:30036398
Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques. PMID:30035760
CRISPR-based reagents to study the influence of the epigenome on gene expression. PMID:30030848
The genomics of insecticide resistance: insights from recent studies in African malaria vectors. PMID:30025626
Noninvasive cancer biomarkers in solid malignancies: circulating tumor DNA-clinical utility, current limitations and future perspectives. PMID:30023396
Retrotransposon-induced mosaicism in the neural genome. PMID:30021882
Rapid Low-Cost Assembly of the Drosophila melanogaster Reference Genome Using Low-Coverage, Long-Read Sequencing. PMID:30018084
GtTR: Bayesian estimation of absolute tandem repeat copy number using sequence capture and high throughput sequencing. PMID:30012093
Molecular biology as a tool for the treatment of cancer. PMID:30006681
Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes. PMID:30005633
Comparative genomic analysis of eutherian adiponectin genes. PMID:30003153
L1 retrotransposition in the soma: a field jumping ahead. PMID:30002735
HIV infection results in clonal expansions containing integrations within pathogenesis-related biological pathways. PMID:29997284
Germline DNA replication timing shapes mammalian genome composition. PMID:29986092
Gene-by-Gene or Localized Dosage Compensation on the Neo-X Chromosome in Drosophila miranda. PMID:29986000
Tetz's theory and law of longevity. PMID:29978435
Machine Learning and Radiogenomics: Lessons Learned and Future Directions. PMID:29977864
LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs. PMID:29976163
Reappraisal of Reported Genes for Sudden Arrhythmic Death: Evidence-Based Evaluation of Gene Validity for Brugada Syndrome. PMID:29959160
G protein-coupled receptors: the evolution of structural insight. PMID:29951585
Haplotype phasing in single-cell DNA-sequencing data. PMID:29950014
Platforms for Investigating LncRNA Functions. PMID:29945466
Ethics and Quality Assessment in Genetic Testing. PMID:29942241
Towards Automation for Molecular Diagnosis of Cancer. PMID:29942240
Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE-1 repression. PMID:29941661
Multigenome analysis implicates miniature inverted-repeat transposable elements (MITEs) in metabolic diversification in eudicots. PMID:29941591
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus. PMID:29937276
Continuous-Trait Probabilistic Model for Comparing Multi-species Functional Genomic Data. PMID:29936186
Identification of transposable elements fused in the exonic region of the olive flounder genome. PMID:29934806
Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca2+ transients in murine heart. PMID:29928770
MALAT1: A long non-coding RNA highly associated with human cancers. PMID:29928382
Construction of Red Fox Chromosomal Fragments from the Short-Read Genome Assembly. PMID:29925783
A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes. PMID:29923268
Horizontally transferred genes in the ctenophore Mnemiopsis leidyi. PMID:29922518
RNA Degradation in Neurodegenerative Disease. PMID:29916018
Motifome comparison between modern human, Neanderthal and Denisovan. PMID:29914355
Predicting human genes susceptible to genomic instability associated with Alu/Alu-mediated rearrangements. PMID:29907612
Clinical validation of the Tempus xO assay. PMID:29899824
Human Genetics of Obesity and Type 2 Diabetes Mellitus: Past, Present, and Future. PMID:29899044
ALUminating the Path of Atherosclerosis Progression: Chaos Theory Suggests a Role for Alu Repeats in the Development of Atherosclerotic Vascular Disease. PMID:29895733
Genetic Diversity in the UV Sex Chromosomes of the Brown Alga Ectocarpus. PMID:29882839
Genetic testing and autism: Tutorial for communication sciences and disorders. PMID:29879582
Cancer epigenetics: Moving forward. PMID:29879107
RNA Editing and Retrotransposons in Neurology. PMID:29875629
Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling. PMID:29872691
DACCOR-Detection, characterization, and reconstruction of repetitive regions in bacterial genomes. PMID:29868249
Long Non-coding RNAs in Endothelial Biology. PMID:29867565
Evolutionary divergence of 3' UTRs in cichlid fishes. PMID:29866078
Evolution, kidney development, and chronic kidney disease. PMID:29857053
Mining the literature for genes associated with placenta-mediated maternal diseases. PMID:29854219
Counteraction of Oxidative Stress by Vitamin E Affects Epigenetic Regulation by Increasing Global Methylation and Gene Expression of MLH1 and DNMT1 Dose Dependently in Caco-2 Cells. PMID:29854080
The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate. PMID:29853174
Landscape of Microsatellite Instability Across 39 Cancer Types. PMID:29850653
Whole-Genome Sequencing in Cancer. PMID:29844223
Long-Distance Relationships: Suppression of Repeat-Mediated Deletions. PMID:29804746
Mining of potential drug targets through the identification of essential and analogous enzymes in the genomes of pathogens of Glycine max, Zea mays and Solanum lycopersicum. PMID:29799863
Prenatal Perfluorooctyl Sulfonate Exposure and Alu DNA Hypomethylation in Cord Blood. PMID:29795014
Moonshot Objectives: Catalyze New Scientific Breakthroughs-Proteogenomics. PMID:29794536
Getting up close and personal with UK genomics and beyond. PMID:29793512
Mutalisk: a web-based somatic MUTation AnaLyIS toolKit for genomic, transcriptional and epigenomic signatures. PMID:29790943
PUF60-activated exons uncover altered 3' splice-site selection by germline missense mutations in a single RRM. PMID:29788428
ZNF418 overexpression protects against gastric carcinoma and prompts a good prognosis. PMID:29785125
All I's on the RADAR: role of ADAR in gene regulation. PMID:29770436
A Next-Generation Sequencing Primer-How Does It Work and What Can It Do? PMID:29761157
Selective modulation of local linkages between active transcription and oxidative demethylation activity shapes cardiomyocyte-specific gene-body epigenetic status in mice. PMID:29747586
Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi's sarcoma development. PMID:29743595
Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation. PMID:29740078
A deeper view into the significance of simple sequence repeats in pre-miRNAs provides clues for its possible roles in determining the function of microRNAs. PMID:29739315
Detection and analysis of ancient segmental duplications in mammalian genomes. PMID:29735604
Towards a map of cis-regulatory sequences in the human genome. PMID:29733395
Copy Number Variation Disorders. PMID:29732242
Genome Editing Redefines Precision Medicine in the Cardiovascular Field. PMID:29731778
Targeting RNA in mammalian systems with small molecules. PMID:29726113
Reconstruction of a replication-competent ancestral murine endogenous retrovirus-L. PMID:29716624
Heritable L1 Retrotransposition Events During Development: Understanding Their Origins: Examination of heritable, endogenous L1 retrotransposition in mice opens up exciting new questions and research directions. PMID:29709066
Predicting gene structure changes resulting from genetic variants via exon definition features. PMID:29701825
Nuclear Signaling of Plant MAPKs. PMID:29696029
Prostate Cancer Genomics: Recent Advances and the Prevailing Underrepresentation from Racial and Ethnic Minorities. PMID:29690565
Differential Effect of Selection against LINE Retrotransposons among Vertebrates Inferred from Whole-Genome Data and Demographic Modeling. PMID:29688421
Effective discovery of rare variants by pooled target capture sequencing: A comparative analysis with individually indexed target capture sequencing. PMID:29677560
Divergent genome evolution caused by regional variation in DNA gain and loss between human and mouse. PMID:29677183
Cell type transcriptome atlas for the planarian Schmidtea mediterranea. PMID:29674431
Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. PMID:29669801
Melanoma: What do all the mutations mean? PMID:29663336
Rare Splice Variants in Long Non-Coding RNAs. PMID:29657294
Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs. PMID:29648536
Identification and characterization of short tandem repeats in the Tibetan macaque genome based on resequencing data. PMID:29643326
L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis. PMID:29643204
Tracking the Continuous Evolutionary Processes of an Endogenous Retrovirus of the Domestic Cat: ERV-DC. PMID:29642384
Genotype imputation performance of three reference panels using African ancestry individuals. PMID:29637265
Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements. PMID:29636371
DNA methylation profiles correlated to striped bass sperm fertility. PMID:29636007
Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering. PMID:29635476
Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors. PMID:29633898
A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms. PMID:29632618
Relationship between Long Interspersed Nuclear Element-1 DNA Methylation in Leukocytes and Dyslipidemia in the Japanese General Population. PMID:29628482
A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1. PMID:29618024
An Evaluation of Function of Multicopy Noncoding RNAs in Mammals Using ENCODE/FANTOM Data and Comparative Genomics. PMID:29617896
A survey and evaluation of Web-based tools/databases for variant analysis of TCGA data. PMID:29617727
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation. PMID:29610582
From "Cellular" RNA to "Smart" RNA: Multiple Roles of RNA in Genome Stability and Beyond. PMID:29600857
Protein-nucleic acid interactions of LINE-1 ORF1p. PMID:29596909
HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity. PMID:29593697
The influence of transcript assembly on the proteogenomics discovery of microproteins. PMID:29584760
HnRNP L represses cryptic exons. PMID:29581412
Evidence for DNA Sequence Encoding of an Accessible Nucleosomal Array across Vertebrates. PMID:29580552
Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations. PMID:29576615
In silico analysis of endogenous siRNAs associated transposable elements and NATs in Schistosoma japonicum reveals their putative roles during reproductive development. PMID:29568977
Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p. PMID:29565245
iPS Cells-The Triumphs and Tribulations. PMID:29563461
Multispecies reconstructions uncover widespread conservation, and lineage-specific elaborations in eukaryotic mRNA metabolism. PMID:29561870
Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort. PMID:29560787
The Ever-Evolving Concept of the Gene: The Use of RNA/Protein Experimental Techniques to Understand Genome Functions. PMID:29560353
Analysis of lineage-specific Alu subfamilies in the genome of the olive baboon, Papio anubis. PMID:29560044
Precision oncology in advanced cancer patients improves overall survival with lower weekly healthcare costs. PMID:29552312
Nimbus: a design-driven analyses suite for amplicon-based NGS data. PMID:29538618
Transcriptional landscape of human endogenous retroviruses (HERVs) and other repetitive elements in psoriatic skin. PMID:29531256
Global analysis of A-to-I RNA editing reveals association with common disease variants. PMID:29527417
Investigation of Endogenous Retrovirus Sequences in the Neighborhood of Genes Up-regulated in a Neuroblastoma Model after Treatment with Hypoxia-Mimetic Cobalt Chloride. PMID:29515560
Human Endogenous Retroviruses and Their Putative Role in the Development of Autoimmune Disorders Such as Multiple Sclerosis. PMID:29515547
Spliced integrated retrotransposed element (SpIRE) formation in the human genome. PMID:29505568
Reading the tea leaves: Dead transposon copies reveal novel host and transposon biology. PMID:29505560
LINE-1 ORF1 Protein Is Up-regulated by Reactive Oxygen Species and Associated with Bladder Urothelial Carcinoma Progression. PMID:29496693
DNA methylation in the pathogenesis of type 2 diabetes in humans. PMID:29496428
Elevated HERV-K Expression in Soft Tissue Sarcoma Is Associated with Worsened Relapse-Free Survival. PMID:29487589
High-Throughput Methods to Detect Long Non-Coding RNAs. PMID:29485610
Agonistic Autoantibodies to the β2-Adrenergic Receptor Involved in the Pathogenesis of Open-Angle Glaucoma. PMID:29483909
Individual retrotransposon integrants are differentially controlled by KZFP/KAP1-dependent histone methylation, DNA methylation and TET-mediated hydroxymethylation in naïve embryonic stem cells. PMID:29482634
Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair. PMID:29474673
Introduction to mammalian genome special issue: the combined role of genetics and environment relevant to human disease outcomes. PMID:29460122
A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts. PMID:29447159
Glia maturation factor-β: a potential therapeutic target in neurodegeneration and neuroinflammation. PMID:29445286
Mutation in an alternative transcript of CDKL5 in a boy with early-onset seizures. PMID:29444904
Evolution of neuropeptide signalling systems. PMID:29440283
Alternative Splicing as a Target for Cancer Treatment. PMID:29439487
Toward a Tiered Model to Share Clinical Trial Data and Samples in Precision Oncology. PMID:29435448
Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas. PMID:29427211
OVAS: an open-source variant analysis suite with inheritance modelling. PMID:29422027
Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach. PMID:29398526
Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases. PMID:29396793
Mammalian transposable elements and their impacts on genome evolution. PMID:29392473
A high throughput screen for active human transposable elements. PMID:29390960
Transcriptome-wide identification of the RNA-binding landscape of the chromatin-associated protein PARP1 reveals functions in RNA biogenesis. PMID:29387452
Co(II) Coordination in Prokaryotic Zinc Finger Domains as Revealed by UV-Vis Spectroscopy. PMID:29386985
Liver X Receptor-Binding DNA Motif Associated With Atherosclerosis-Specific DNA Methylation Profiles of Alu Elements and Neighboring CpG Islands. PMID:29386205
Illumina Library Preparation for Sequencing the GC-Rich Fraction of Heterogeneous Genomic DNA. PMID:29385572
Serum DNA integrity index as a potential molecular biomarker in endometrial cancer. PMID:29382392
Rheumatoid arthritis patient antibodies highly recognize IL-2 in the immune response pathway involving IRF5 and EBV antigens. PMID:29379122
Protecting and Diversifying the Germline. PMID:29378808
Cognitive genomics: Searching for the genetic roots of neuropsychological functioning. PMID:29376674
Intraspecific and intraorganismal copy number dynamics of retrotransposons and tandem repeat in Aegilops speltoides Tausch (Poaceae, Triticeae). PMID:29374788
Patterns of variation in cis-regulatory regions: examining evidence of purifying selection. PMID:29373957
Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control. PMID:29367313
Plasmodium parasites of birds have the most AT-rich genes of eukaryotes. PMID:29360019
The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution. PMID:29358652
Reccurrent F8 Intronic Deletion Found in Mild Hemophilia A Causes Alu Exonization. PMID:29357978
Beta and Gamma Human Herpesviruses: Agonistic and Antagonistic Interactions with the Host Immune System. PMID:29354096
qPortal: A platform for data-driven biomedical research. PMID:29352322
GenomeLandscaper: Landscape analysis of genome-fingerprints maps assessing chromosome architecture. PMID:29348569
Natural antisense transcripts in diseases: From modes of action to targeted therapies. PMID:29341438
Contribution of transposable elements and distal enhancers to evolution of human-specific features of interphase chromatin architecture in embryonic stem cells. PMID:29335803
Transposable elements: genome innovation, chromosome diversity, and centromere conflict. PMID:29332159
High expression of Endogenous Retroviruses from intrauterine life to adulthood in two mouse models of Autism Spectrum Disorders. PMID:29330412
Large genomic insertion at the Shh locus results in hammer toes through enhancer adoption. PMID:29330329
Retrovirus-like Gag Protein Arc1 Binds RNA and Traffics across Synaptic Boutons. PMID:29328915
Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders. PMID:29327725
Analysis of DNA modifications in aging research. PMID:29327208
Dissection of Myogenic Differentiation Signatures in Chickens by RNA-Seq Analysis. PMID:29324704
Investigation and identification of functional post-translational modification sites associated with drug binding and protein-protein interactions. PMID:29322920
Using Genome Sequence to Enable the Design of Medicines and Chemical Probes. PMID:29322778
Structural and Evolutionary Relationships in the Giant Sex Chromosomes of Three Microtus Species. PMID:29320452
Identification of Inherited Retinal Disease-Associated Genetic Variants in 11 Candidate Genes. PMID:29320387
Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition. PMID:29315404
Identification of Transposable Elements Contributing to Tissue-Specific Expression of Long Non-Coding RNAs. PMID:29315213
The lncRNA-HOXA-AS2/EZH2/LSD1 oncogene complex promotes cell proliferation in pancreatic cancer. PMID:29312501
Potential Links between Hepadnavirus and Bornavirus Sequences in the Host Genome and Cancer. PMID:29312227
Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes. PMID:29312197
The Importance of ncRNAs as Epigenetic Mechanisms in Phenotypic Variation and Organic Evolution. PMID:29312192
Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region. PMID:29311362
LINE-1 protein localization and functional dynamics during the cell cycle. PMID:29309036
Dissection of affinity captured LINE-1 macromolecular complexes. PMID:29309035
Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells. PMID:29308092
Endogenous LINE-1 (Long Interspersed Nuclear Element-1) Reverse Transcriptase Activity in Platelets Controls Translational Events Through RNA-DNA Hybrids. PMID:29301786
The effects of transcription and recombination on mutational dynamics of short tandem repeats. PMID:29300948
The development and growth of EJHG 1995-2017. PMID:29297878
Erythrogene: a database for in-depth analysis of the extensive variation in 36 blood group systems in the 1000 Genomes Project. PMID:29296939
Alu element insertion in PKLR gene as a novel cause of pyruvate kinase deficiency in Middle Eastern patients. PMID:29288557
Overexpressed HSF1 cancer signature genes cluster in human chromosome 8q. PMID:29268782
From a retrovirus infection of mice to a long noncoding RNA that induces proto-oncogene transcription and oncogenesis via an epigenetic transcription switch. PMID:29263895
Was the Watchmaker Blind? Or Was She One-Eyed? PMID:29261138
Recognizing the SINEs of Infection: Regulation of Retrotransposon Expression and Modulation of Host Cell Processes. PMID:29258254
De-novo emergence of SINE retroposons during the early evolution of passerine birds. PMID:29255493
Single molecule sequencing of the M13 virus genome without amplification. PMID:29253901
Analysis of the Expression of Repetitive DNA Elements in Osteosarcoma. PMID:29250102
Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles. PMID:29246318
LINE-1 retrotransposons in healthy and diseased human brain. PMID:29239145
Circular RNAs: A novel type of non-coding RNA and their potential implications in antiviral immunity. PMID:29230098
Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1. PMID:29229810
Identification of differentially expressed genes, lncRNAs and miRNAs which are associated with tumor malignant phenotypes in hepatoblastoma patients. PMID:29228631
Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort. PMID:29228364
Patient Engagement in Kidney Research: Opportunities and Challenges Ahead. PMID:29225906
Transcription coupled repair and biased insertion of human retrotransposon L1 in transcribed genes. PMID:29225704
Diagnostic and prognostic tests in systemic lupus erythematosus. PMID:29224677
Integrating 5hmC and gene expression data to infer regulatory mechanisms. PMID:29220513
Computational identification of harmful mutation regions to the activity of transposable elements. PMID:29219079
Lessons from the Human Genome Project: Modesty, Honesty, and Realism. PMID:29218057
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators. PMID:29211708
Living Organisms Author Their Read-Write Genomes in Evolution. PMID:29211049
Whole-exome sequencing of sickle cell disease patients with hyperhemolysis syndrome suggests a role for rare variation in disease predisposition. PMID:29210071
Transposable Element Mediated Innovation in Gene Regulatory Landscapes of Cells: Re-Visiting the "Gene-Battery" Model. PMID:29206283
Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain. PMID:29201157
The rise of the genome and personalised medicine. PMID:29196356
Decontaminating eukaryotic genome assemblies with machine learning. PMID:29191179
A Multilayered Control of the Human Survival Motor Neuron Gene Expression by Alu Elements. PMID:29187847
Genomic copy number variation analysis in multiple system atrophy. PMID:29187220
Functional horizontal gene transfer from bacteria to eukaryotes. PMID:29176581
Catching hidden variation: systematic correction of reference minor allele annotation in clinical variant calling. PMID:29155419
Molecular Crosstalking among Noncoding RNAs: A New Network Layer of Genome Regulation in Cancer. PMID:29147648
The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation. PMID:29142137
DNA damage responses and p53 in the aging process. PMID:29141944
The European Nucleotide Archive in 2017. PMID:29140475
Genomic structural variations lead to dysregulation of important coding and non-coding RNA species in dilated cardiomyopathy. PMID:29138229
Optimized approach for the identification of highly efficient correctors of nonsense mutations in human diseases. PMID:29131862
Improving virtual screening of G protein-coupled receptors via ligand-directed modeling. PMID:29131821
Significance of functional disease-causal/susceptible variants identified by whole-genome analyses for the understanding of human diseases. PMID:29129848
Neurobiology: A genetic cause of age-related decline. PMID:29120415
Alternative splicing regulation in tumor necrosis factor-mediated inflammation. PMID:29113151
Detection of subclonal L1 transductions in colorectal cancer by long-distance inverse-PCR and Nanopore sequencing. PMID:29109480
The first draft reference genome of the American mink (Neovison vison). PMID:29109430
Coevolution between transposable elements and recombination. PMID:29109221
RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology and biomedical applications. PMID:29105333
A Role for the Mutagenic DNA Self-Catalyzed Depurination Mechanism in the Evolution of 7SL-Derived RNAs. PMID:29103173
An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells. PMID:29100015
Can Probiotic Supplements Improve Outcomes in Rheumatoid Arthritis? PMID:29094223
A Never Ending Story.. PMID:29090025
The shortening of leukocyte telomere length relates to DNA hypermethylation of LINE-1 in type 2 diabetes mellitus. PMID:29088760
Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders. PMID:29084565
Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth. PMID:29075358
BBMerge - Accurate paired shotgun read merging via overlap. PMID:29073143
Molecular determinants of beta-adrenergic signaling to voltage-gated K+ channels in the cerebral circulation. PMID:29072364
Epigenetics and precision medicine in cardiovascular patients: from basic concepts to the clinical arena. PMID:29069341
Pivotal Impacts of Retrotransposon Based Invasive RNAs on Evolution. PMID:29067016
A Review of Recent Advances in Translational Bioinformatics: Bridges from Biology to Medicine. PMID:29063562
The emerging roles of NGS-based liquid biopsy in non-small cell lung cancer. PMID:29061113
Genome-wide association study reveals genetic loci and candidate genes for average daily gain in Duroc pigs. PMID:29059722
PopHuman: the human population genomics browser. PMID:29059408
Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues. PMID:29058714
[Big Data Revolution or Data Hubris? : On the Data Positivism of Molecular Biology]. PMID:29058018
DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice. PMID:29051587
Precision medicine for all? Challenges and opportunities for a precision medicine approach to critical illness. PMID:29047353
The role of gene variants in the pathogenesis of neurodegenerative disorders as revealed by next generation sequencing studies: a review. PMID:29046784
HIV-1 Infection of Primary CD4+ T Cells Regulates the Expression of Specific Human Endogenous Retrovirus HERV-K (HML-2) Elements. PMID:29046457
Ribosome Biogenesis Modulates Ty1 Copy Number Control in Saccharomyces cerevisiae. PMID:29046400
The Antibody Repertoire of Colorectal Cancer. PMID:29046389
Integrating networks and comparative genomics reveals retroelement proliferation dynamics in hominid genomes. PMID:29043294
A plasma proteomics method reveals links between ischemic stroke and MTHFR C677T genotype. PMID:29042595
Human Genome Sequencing at the Population Scale: A Primer on High-Throughput DNA Sequencing and Analysis. PMID:29040395
Highly sensitive and specific Alu-based quantification of human cells among rodent cells. PMID:29038571
Striking a balance: regulation of transposable elements by Zfp281 and Mll2 in mouse embryonic stem cells. PMID:29036642
cuRRBS: simple and robust evaluation of enzyme combinations for reduced representation approaches. PMID:29036576
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a. PMID:29033588
Emerging and evolving concepts in gene essentiality. PMID:29033457
Software Dedicated to Virus Sequence Analysis "Bioinformatics Goes Viral". PMID:29029728
Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells. PMID:29028794
CRISPR/Cas9-mediated noncoding RNA editing in human cancers. PMID:29028415
High-resolution mapping of the pericentromeric region on wheat chromosome arm 5AS harbouring the Fusarium head blight resistance QTL Qfhs.ifa-5A. PMID:29024288
Adaptive self-organization in the embryo: its importance to adult anatomy and to tissue engineering. PMID:29023694
Comprehensive benchmarking of SNV callers for highly admixed tumor data. PMID:29020110
DNA sequencing at 40: past, present and future. PMID:29019985
Differential gene regulatory networks in development and disease. PMID:29018868
FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling. PMID:28988985
STRScan: targeted profiling of short tandem repeats in whole-genome sequencing data. PMID:28984185
MicroRNA miR-128 represses LINE-1 (L1) retrotransposition by down-regulating the nuclear import factor TNPO1. PMID:28974576
Human evolution: the non-coding revolution. PMID:28969617
LINC00052 upregulates EPB41L3 to inhibit migration and invasion of hepatocellular carcinoma by binding miR-452-5p. PMID:28969024
Clinical interpretation of copy number variants in the human genome. PMID:28963714
Reference genome assessment from a population scale perspective: an accurate profile of variability and noise. PMID:28961772
Multiomics Approach to Asthma: Navigating the Network. PMID:28960106
RNase H As Gene Modifier, Driver of Evolution and Antiviral Defense. PMID:28959243
Functional Mechanisms of Microsatellite DNA in Eukaryotic Genomes. PMID:28957459
Modeling GATAD1-Associated Dilated Cardiomyopathy in Adult Zebrafish. PMID:28955713
Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. PMID:28951865
STEAK: A specific tool for transposable elements and retrovirus detection in high-throughput sequencing data. PMID:28948042
Similar Evolutionary Trajectories for Retrotransposon Accumulation in Mammals. PMID:28945883
Exosomal lncRNA GAS5 regulates the apoptosis of macrophages and vascular endothelial cells in atherosclerosis. PMID:28945793
MicroRNAs in Heart Failure, Cardiac Transplantation, and Myocardial Recovery: Biomarkers with Therapeutic Potential. PMID:28940102
Population-wide sampling of retrotransposon insertion polymorphisms using deep sequencing and efficient detection. PMID:28938719
Host Noncoding Retrotransposons Induced by DNA Viruses: a SINE of Infection? PMID:28931686
"Multi-Omics" Analyses of the Development and Function of Natural Killer Cells. PMID:28928751
Satellite DNA: An Evolving Topic. PMID:28926993
Elucidation of complexity and prediction of interactions in microbial communities. PMID:28925555
Augmented expression of polo-like kinase 1 indicates poor clinical outcome for breast patients: a systematic review and meta-analysis. PMID:28915707
Prediction of genome-wide DNA methylation in repetitive elements. PMID:28911103
Distribution, Diversity, and Long-Term Retention of Grass Short Interspersed Nuclear Elements (SINEs). PMID:28903462
Cell-free circulating DNA integrity is an independent predictor of impending breast cancer recurrence. PMID:28903362
Alu-based cell-free DNA: a novel biomarker for screening of gastric cancer. PMID:28903321
Comparative Genomic In Situ Hybridization and the Possible Role of Retroelements in the Karyotypic Evolution of Three Akodontini Species. PMID:28900618
Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer. PMID:28893944
Recent Advances in Experimental Whole Genome Haplotyping Methods. PMID:28891974
Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia. PMID:28887438
Bias and Correction in RNA-seq Data for Marine Species. PMID:28884399
Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids. PMID:28883691
Deamination-independent restriction of LINE-1 retrotransposition by APOBEC3H. PMID:28883657
A practical guide to build de-novo assemblies for single tissues of non-model organisms: the example of a Neotropical frog. PMID:28879061
Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding. PMID:28877740
The Exposome: A New Frontier for Education. PMID:28867821
Fifty years in human genetics--a career retrospective. PMID:28860307
Identification of novel inhibitors against Cyclin Dependent Kinase 9/Cyclin T1 complex as: Anti cancer agent. PMID:28855816
MSDB: A Comprehensive Database of Simple Sequence Repeats. PMID:28854643
rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline. PMID:28854222
RNA biology of disease-associated microsatellite repeat expansions. PMID:28851463
The complexity of TRIM28 contribution to cancer. PMID:28851455
Falling giants and the rise of gene editing: ethics, private interests and the public good. PMID:28851444
Effect of health-belief-model-based training on performance of women in breast self-examination. PMID:28848633
Short and Long Noncoding RNAs Regulate the Epigenetic Status of Cells. PMID:28847161
Genomic Analysis of the DNA Replication Timing Program during Mitotic S Phase in Maize (Zea mays) Root Tips. PMID:28842533
Evolution viewed from physics, physiology and medicine. PMID:28839924
Biological action in Read-Write genome evolution. PMID:28839913
A new role for FBP21 as regulator of Brr2 helicase activity. PMID:28838205
Long noncoding RNAs coordinate functions between mitochondria and the nucleus. PMID:28835257
Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers. PMID:28830571
Human Retrotransposon Insertion Polymorphisms Are Associated with Health and Disease via Gene Regulatory Phenotypes. PMID:28824558
p53 binding sites in normal and cancer cells are characterized by distinct chromatin context. PMID:28820292
Exploitation of Gene Expression and Cancer Biomarkers in Paving the Path to Era of Personalized Medicine. PMID:28813639
The Retinoblastoma (RB) Tumor Suppressor: Pushing Back against Genome Instability on Multiple Fronts. PMID:28812991
Discovery of Variants Underlying Host Susceptibility to Virus Infection Using Whole-Exome Sequencing. PMID:28808973
A psychology of the human brain-gut-microbiome axis. PMID:28804508
Silencing of Repetitive DNA Is Controlled by a Member of an Unusual Caenorhabditis elegans Gene Family. PMID:28801529
Examining non-LTR retrotransposons in the context of the evolving primate brain. PMID:28800766
Large Introns of 5 to 10 Kilo Base Pairs Can Be Spliced out in Arabidopsis. PMID:28800125
Splicing and transcription touch base: co-transcriptional spliceosome assembly and function. PMID:28792005
Human genome-microbiome interaction: metagenomics frontiers for the aetiopathology of autoimmune diseases. PMID:28785422
Genetically improved BarraCUDA. PMID:28785314
"Squirrel" Primer-Based PCR Assay for Direct and Targeted Sanger Sequencing of Short Genomic Segments. PMID:28785174
Presence of a Shared 5'-Leader Sequence in Ancestral Human and Mammalian Retroviruses and Its Transduction into Feline Leukemia Virus. PMID:28768854
Impact of Alternative Splicing on the Human Proteome. PMID:28768205
Novel copy number variation of POMGNT1 associated with muscle-eye-brain disease detected by next-generation sequencing. PMID:28765568
Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks. PMID:28765560
Epigenetics of colorectal cancer: emerging circulating diagnostic and prognostic biomarkers. PMID:28758105
Mobile DNA in Health and Disease. PMID:28745987
Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity. PMID:28743002
How should novelty be valued in science? PMID:28742499
Resolving the prevalence of somatic transposition in Drosophila. PMID:28742021
Dissecting evolution and disease using comparative vertebrate genomics. PMID:28736437
ATM supports gammaherpesvirus replication by attenuating type I interferon pathway. PMID:28732227
A novel isoform of IL-33 revealed by screening for transposable element promoted genes in human colorectal cancer. PMID:28715472
Regulatory Roles of Long Non-Coding RNAs in the Central Nervous System and Associated Neurodegenerative Diseases. PMID:28713244
Sensorimotor Learning: Neurocognitive Mechanisms and Individual Differences. PMID:28705227
Genomic analysis of an infant with intractable diarrhea and dilated cardiomyopathy. PMID:28701297
Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses. PMID:28700586
Genetics and ALS: Cause for Optimism. PMID:28698777
Medicine's movable feast: What jumping genes can teach us about treating disease. PMID:28697180
Host genetic variation and HIV disease: from mapping to mechanism. PMID:28695282
The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics. PMID:28691345
Materials Knowledge Systems in Python - A Data Science Framework for Accelerated Development of Hierarchical Materials. PMID:28690971
LINE-1 hypomethylation is not a common event in preneoplastic stages of gastric carcinogenesis. PMID:28684753
Interpreting whole genome and exome sequencing data of individual gastric cancer samples. PMID:28683819
A Cell Fusion-Based Screening Method Identifies Glycosylphosphatidylinositol-Anchored Protein Ly6e as the Receptor for Mouse Endogenous Retroviral Envelope Syncytin-A. PMID:28679758
Spectraplakin family proteins - cytoskeletal crosslinkers with versatile roles. PMID:28679697
Modeling human disease in rodents by CRISPR/Cas9 genome editing. PMID:28677007
The Exposome Paradigm in Human Health: Lessons from the Emory Exposome Summer Course. PMID:28669935
LTRs of Endogenous Retroviruses as a Source of Tbx6 Binding Sites. PMID:28664156
Landscape and variation of novel retroduplications in 26 human populations. PMID:28662076
The Piwi-piRNA pathway: road to immortality. PMID:28653810
Haplotype phasing of whole human genomes using bead-based barcode partitioning in a single tube. PMID:28650462
Transposable elements in cancer. PMID:28642606
Managing the genomic revolution in cancer diagnostics. PMID:28639053
Differential chromosomal organization between Saguinus midas and Saguinus bicolor with accumulation of differences the repetitive sequence DNA. PMID:28634866
Increasing the reach of forensic genetics with massively parallel sequencing. PMID:28631109
Molecular mechanisms of experience-dependent maturation in cortical GABAergic inhibition. PMID:28628196
A water-soluble DsbB variant that catalyzes disulfide-bond formation in vivo. PMID:28628094
Utilization of genomic sequencing for population screening of immunodeficiencies in the newborn. PMID:28617419
Expression of HERV-K108 envelope interferes with HIV-1 production. PMID:28605635
The Genomic Impact of Gene Retrocopies: What Have We Learned from Comparative Genomics, Population Genomics, and Transcriptomic Analyses? PMID:28605529
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats. PMID:28604729
Primate-specific Long Non-coding RNAs and MicroRNAs. PMID:28602844
Interplay between viruses and bacterial microbiota in cancer development. PMID:28602713
Genome-wide mapping and characterization of microsatellites in the swamp eel genome. PMID:28600492
Dissecting LSD1-Dependent Neuronal Maturation in the Olfactory Epithelium. PMID:28597915
Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability. PMID:28591191
A conserved role for the ESCRT membrane budding complex in LINE retrotransposition. PMID:28586350
Large normal-range TBP and ATXN7 CAG repeat lengths are associated with increased lifetime risk of depression. PMID:28585930
Analysis of LINE-1 Elements in DNA from Postmortem Brains of Individuals with Schizophrenia. PMID:28585566
High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development. PMID:28581499
Transposable elements in Drosophila. PMID:28580197
Genome-Wide Comparative Analysis of Miniature Inverted Repeat Transposable Elements in 19 Arabidopsis thaliana Ecotype Accessions. PMID:28572566
The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping. PMID:28569263
Epigenetic Control of Human Endogenous Retrovirus Expression: Focus on Regulation of Long-Terminal Repeats (LTRs). PMID:28561791
The Role of Somatic L1 Retrotransposition in Human Cancers. PMID:28561751
Clinically Focused Molecular Investigation of 1000 Consecutive Families with Inherited Retinal Disease. PMID:28559085
Genome annotation for clinical genomic diagnostics: strengths and weaknesses. PMID:28558813
A birth of bipartite exon by intragenic deletion. PMID:28546999
Refining the ideas of "ethnic" skin. PMID:28538883
Methylation Levels of LINE-1 As a Useful Marker for Venous Invasion in Both FFPE and Frozen Tumor Tissues of Gastric Cancer. PMID:28535662
Last rolls of the yoyo: Assessing the human canonical protein count. PMID:28529709
L1 retrotransposition is activated by Ten-eleven-translocation protein 1 and repressed by methyl-CpG binding proteins. PMID:28524723
Reading LINEs within the cocaine addicted brain. PMID:28523221
Identification of human short introns. PMID:28520720
DNA Sequence Analysis in Clinical Medicine, Proceeding Cautiously. PMID:28516087
Robust long-read native DNA sequencing using the ONT CsgG Nanopore system. PMID:28503666
Metazoan Ribosome Inactivating Protein encoding genes acquired by Horizontal Gene Transfer. PMID:28500327
Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution. PMID:28500258
Relationship between regulatory pattern of gene expression level and gene function. PMID:28494005
Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration. PMID:28491150
Evidence for transcriptome-wide RNA editing among Sus scrofa PRE-1 SINE elements. PMID:28486975
Natural Variation in the Distribution and Abundance of Transposable Elements Across the Caenorhabditis elegans Species. PMID:28486636
Horizontal gene transfer is not a hallmark of the human genome. PMID:28482857
Soft Sweeps Are the Dominant Mode of Adaptation in the Human Genome. PMID:28482049
Comparative transcriptomics in human and mouse. PMID:28479595
Contrasting Sex-and Caste-Dependent piRNA Profiles in the Transposon Depleted Haplodiploid Honeybee Apis mellifera. PMID:28472327
Reliability of algorithmic somatic copy number alteration detection from targeted capture data. PMID:28472276
EnHERV: Enrichment analysis of specific human endogenous retrovirus patterns and their neighboring genes. PMID:28472109
Improving your four-dimensional image: traveling through a decade of light-sheet-based fluorescence microscopy research. PMID:28471459
Structural variants caused by Alu insertions are associated with risks for many human diseases. PMID:28465436
T-cell activation RhoGTPase-activating protein plays an important role in TH17-cell differentiation. PMID:28462950
A novel MERTK mutation causing retinitis pigmentosa. PMID:28462455
Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart. PMID:28460026
LINE Insertion Polymorphisms are Abundant but at Low Frequencies across Populations of Anolis carolinensis. PMID:28450881
Coronins and their role in immunological phenomena. PMID:28450807
Construction of a map-based reference genome sequence for barley, Hordeum vulgare L. PMID:28448065
Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project. PMID:28448031
Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity. PMID:28446240
Small RNA Pathways That Protect the Somatic Genome. PMID:28445427
The evolution of neuropeptide signalling: insights from echinoderms. PMID:28444138
Evolutionary history of the extant amphioxus lineage with shallow-branching diversification. PMID:28442709
Implementing an Internet-Delivered Skin Cancer Genetic Testing Intervention to Improve Sun Protection Behavior in a Diverse Population: Protocol for a Randomized Controlled Trial. PMID:28442450
Early vertebrate origin and diversification of small transmembrane regulators of cellular ion transport. PMID:28436536
Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans. PMID:28431148
Large-scale collection of full-length cDNA and transcriptome analysis in Hevea brasiliensis. PMID:28431015
Global Fecal and Plasma Metabolic Dynamics Related to Helicobacter pylori Eradication. PMID:28424674
Molecular genetics: Chaperone protein gets personal. PMID:28424517
Identification and characterization of L1-specific endo-siRNAs essential for early embryonic development in pig. PMID:28423565
Sharing Data to Build a Medical Information Commons: From Bermuda to the Global Alliance. PMID:28415857
Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene. PMID:28415677
Long non-coding RNAs in cutaneous melanoma: clinical perspectives. PMID:28415644
Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes. PMID:28406751
Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals. PMID:28403820
SnoVault and encodeD: A novel object-based storage system and applications to ENCODE metadata. PMID:28403240
Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors. PMID:28397686
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly. PMID:28396521
Scaling by shrinking: empowering single-cell 'omics' with microfluidic devices. PMID:28392571
A comprehensive hybridization model allows whole HERV transcriptome profiling using high density microarray. PMID:28390408
DNA word analysis based on the distribution of the distances between symmetric words. PMID:28389642
Monochromosomal Hybrids and Chromosome Transfer: A Functional Approach for Gene Identification. PMID:28387649
Multi-scale chromatin state annotation using a hierarchical hidden Markov model. PMID:28387224
Precision Cardiovascular Medicine: State of Genetic Testing. PMID:28385198
Translation of Nutritional Genomics into Nutrition Practice: The Next Step. PMID:28383492
Direct determination of diploid genome sequences. PMID:28381613
Structural features embedded in G protein-coupled receptor co-crystal structures are key to their success in virtual screening. PMID:28380046
Spontaneous Mutation Rate in the Smallest Photosynthetic Eukaryotes. PMID:28379581
Widespread of horizontal gene transfer in the human genome. PMID:28376762
Milestones in pathology-from histology to molecular biology. PMID:28367253
Ensembl core software resources: storage and programmatic access for DNA sequence and genome annotation. PMID:28365736
Genome graphs and the evolution of genome inference. PMID:28360232
The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation. PMID:28359286
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. PMID:28351387
Reflection on Molecular Approaches Influencing State-of-the-Art Bioremediation Design: Culturing to Microbial Community Fingerprinting to Omics. PMID:28348455
Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus. PMID:28348391
INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes. PMID:28344990
The feasibility of genome-scale biological network inference using Graphics Processing Units. PMID:28344638
Variants in the host genome may inhibit tumour growth in devil facial tumours: evidence from genome-wide association. PMID:28341828
Schizosaccharomyces pombe MutSα and MutLα Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats. PMID:28341698
De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds. PMID:28336562
DNA Sequencing Sensors: An Overview. PMID:28335417
PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4. PMID:28332630
When Should Genetic Testing Be Performed in Epilepsy Patients? PMID:28331464
Intragenic multi-exon deletion in the FBN1 gene in a child with mildly dilated aortic sinus: a retrotransposal event. PMID:28331219
Gene-based genome-wide association study identified 19p13.3 for lean body mass. PMID:28322352
Identification and Expression of Equine MER-Derived miRNAs. PMID:28320202
From Sequence Data to Returnable Results: Ethical Issues in Variant Calling and Interpretation. PMID:28306396
Y chromosome palindromes and gene conversion. PMID:28303348
Editing the genome of hiPSC with CRISPR/Cas9: disease models. PMID:28303292
Epigenetic and genetic alterations and their influence on gene regulation in chronic lymphocytic leukemia. PMID:28302063
Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer. PMID:28300471
ThermoAlign: a genome-aware primer design tool for tiled amplicon resequencing. PMID:28300202
Functional interrogation of non-coding DNA through CRISPR genome editing. PMID:28288828
Integration site selection by retroviruses and transposable elements in eukaryotes. PMID:28286338
The Peach v2.0 release: high-resolution linkage mapping and deep resequencing improve chromosome-scale assembly and contiguity. PMID:28284188
Molecular Tumor Boards: Ethical Issues in the New Era of Data Medicine. PMID:28281147
Characterization of contiguous gene deletions in COL4A6 and COL4A5 in Alport syndrome-diffuse leiomyomatosis. PMID:28275241
Non-coding RNA: It's Not Junk. PMID:28271304
Precision medicine driven by cancer systems biology. PMID:28265786
Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome. PMID:28263316
Analytical Biases Associated with GC-Content in Molecular Evolution. PMID:28261263
Extracellular vesicles as trans-genomic agents: Emerging roles in disease and evolution. PMID:28256033
Genomic landscape of CpG rich elements in human. PMID:28251877
Diversity in non-repetitive human sequences not found in the reference genome. PMID:28250455
High-Throughput Proteomic Approaches to the Elucidation of Potential Biomarkers of Chronic Allograft Injury (CAI). PMID:28250402
Protein-Protein Interactions: Gene Acronym Redundancies and Current Limitations Precluding Automated Data Integration. PMID:28250396
The lncRNA XIST exhibits oncogenic properties via regulation of miR-449a and Bcl-2 in human non-small cell lung cancer. PMID:28248928
Omics Approaches for the Study of Adaptive Immunity to Staphylococcus aureus and the Selection of Vaccine Candidates. PMID:28248221
Conserved expression of transposon-derived non-coding transcripts in primate stem cells. PMID:28245871
Targeting Splicing in the Treatment of Human Disease. PMID:28245575
The Isochores as a Fundamental Level of Genome Structure and Organization: A General Overview. PMID:28243687
Role of Protein Phosphatase 2A in Osteoblast Differentiation and Function. PMID:28241467
GSA and BIGD: Filling the Gap of Bioinformatics Resource and Service in China<sup/> PMID:28235641
Evolution of Brain Active Gene Promoters in Human Lineage Towards the Increased Plasticity of Gene Regulation. PMID:28233272
ABySS 2.0: resource-efficient assembly of large genomes using a Bloom filter. PMID:28232478
Population and clinical genetics of human transposable elements in the (post) genomic era. PMID:28228978
Comparative genomic analysis of eutherian kallikrein genes. PMID:28224083
MicroRNAs in model and complex organisms. PMID:28220336
Big Data Analytics for Genomic Medicine. PMID:28212287
Alu-Derived Alternative Splicing Events Specific to Macaca Lineages in CTSF Gene. PMID:28196413
Opportunities and challenges of whole-genome and -exome sequencing. PMID:28193154
Lateral gene transfer between prokaryotes and eukaryotes. PMID:28189637
The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia. PMID:28188229
An accurate and efficient method for large-scale SSR genotyping and applications. PMID:28184437
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. PMID:28178237
The Evolution of LINE-1 in Vertebrates. PMID:28175298
Dicer, a new regulator of pluripotency exit and LINE-1 elements in mouse embryonic stem cells. PMID:28174687
Hypermethylated LTR retrotransposon exhibits enhancer activity. PMID:28165867
Genome-wide mining and comparative analysis of microsatellites in three macaque species. PMID:28160080
Silencing of endogenous retroviruses by heterochromatin. PMID:28160052
Evolution and Diversity of Transposable Elements in Vertebrate Genomes. PMID:28158585
What's in a name? Context-dependent significance of 'global' methylation measures in human health and disease. PMID:28149330
MISTIC-fusion proteins as antigens for high quality membrane protein antibodies. PMID:28148968
Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. PMID:28145450
CRISPR applications in ophthalmologic genome surgery. PMID:28141764
Chicken (Gallus gallus) endogenous retrovirus generates genomic variations in the chicken genome. PMID:28138342
Evolving health care through personal genomics. PMID:28138143
Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function. PMID:28132025
Genetic Disorders of Dental Development: Tales from the Bony Crypt. PMID:28124261
Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy? PMID:28124081
Association of new deletion/duplication region at chromosome 1p21 with intellectual disability, severe speech deficit and autism spectrum disorder-like behavior: an all-in approach to solving the DPYD enigma. PMID:28123791
How close are we to complete annotation of metabolomes? PMID:28113135
Recent advances in understanding neuropathic pain: glia, sex differences, and epigenetics. PMID:28105313
Concise Review: Induced Pluripotent Stem Cell Research in the Era of Precision Medicine. PMID:28100040
Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer. PMID:28096347
Cryptosporidium hominis gene catalog: a resource for the selection of novel Cryptosporidium vaccine candidates. PMID:28095366
Paracoccidioides spp. catalases and their role in antioxidant defense against host defense responses. PMID:28093309
GExplore 1.4: An expanded web interface for queries on Caenorhabditis elegans protein and gene function. PMID:28090394
The future of transposable element annotation and their classification in the light of functional genomics - what we can learn from the fables of Jean de la Fontaine? PMID:28090383
Transposable elements and circular DNAs. PMID:28090380
Clinical and biological insights from viral genome sequencing. PMID:28090077
Single genome retrieval of context-dependent variability in mutation rates for human germline. PMID:28086752
Molecular Evolution of piggyBac Superfamily: From Selfishness to Domestication. PMID:28082605
Computational Prediction of the Global Functional Genomic Landscape: Applications, Methods, and Challenges. PMID:28076869
The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes. PMID:28076790
Human Endogenous Retroviruses-K (HML-2) Expression Is Correlated with Prognosis and Progress of Hepatocellular Carcinoma. PMID:28070518
Effects of Replication and Transcription on DNA Structure-Related Genetic Instability. PMID:28067787
Genetic conflicts: the usual suspects and beyond. PMID:28057823
Insertion Polymorphisms of Mobile Genetic Elements in Sexual and Asexual Populations of Daphnia pulex. PMID:28057730
Exploring the Underlying Genetics of Craniofacial Morphology through Various Sources of Knowledge. PMID:28053980
Short intron-derived ncRNAs. PMID:28053119
The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition. PMID:28049704
Advancement of the Emerging Field of RNA Nanotechnology. PMID:28045501
Tumor LINE-1 Methylation Level in Association with Survival of Patients with Stage II Colon Cancer. PMID:28035987
Novel Role of 3'UTR-Embedded Alu Elements as Facilitators of Processed Pseudogene Genesis and Host Gene Capture by Viral Genomes. PMID:28033411
Barriers to Infection of Human Cells by Feline Leukemia Virus: Insights into Resistance to Zoonosis. PMID:28031367
GeneBase 1.1: a tool to summarize data from NCBI gene datasets and its application to an update of human gene statistics. PMID:28025344
Combined microfluidic-optical DNA analysis with single-base-pair sizing capability. PMID:28018736
Friend or Foe: Epigenetic Regulation of Retrotransposons in Mammalian Oogenesis and Early Development. PMID:28018140
High-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE. PMID:28011790
EhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis. PMID:28002502
The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells. PMID:27999094
Human population-specific gene expression and transcriptional network modification with polymorphic transposable elements. PMID:27998931
Useful parasites: the evolutionary biology and biotechnology applications of transposable elements. PMID:27994207
Perspectives on the history of evo-devo and the contemporary research landscape in the genomics era. PMID:27994116
The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation. PMID:27980690
Endogenous retroviral promoter exaptation in human cancer. PMID:27980689
Performance evaluation for rapid detection of pan-cancer microsatellite instability with MANTIS. PMID:27980218
Efficient Breeding by Genomic Mating. PMID:27965707
Engineered LINE-1 retrotransposition in nondividing human neurons. PMID:27965292
Alternate-locus aware variant calling in whole genome sequencing. PMID:27964746
Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer. PMID:27955637
Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. PMID:27942596
Incorporate gene signature profiling into routine molecular testing. PMID:27942443
Tools for Sequence-Based miRNA Target Prediction: What to Choose? PMID:27941681
High-Throughput Next-Generation Sequencing of Polioviruses. PMID:27927929
L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes. PMID:27924012
Pseudogenes and Their Genome-Wide Prediction in Plants. PMID:27916797
Replication stalling and DNA microsatellite instability. PMID:27914716
Molecular mechanism of hepatitis B virus (HBV) on suppression of raf kinase inhibitor protein (RKIP) expression. PMID:27902472
Patterns of Transposable Element Expression and Insertion in Cancer. PMID:27900322
The BIG Data Center: from deposition to integration to translation. PMID:27899658
A comprehensive approach to expression of L1 loci. PMID:27899577
Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda. PMID:27897175
Blood-based DNA methylation as biomarker for breast cancer: a systematic review. PMID:27895805
Single Amino Acid Repeats in the Proteome World: Structural, Functional, and Evolutionary Insights. PMID:27893794
An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences. PMID:27889452
ProtLID, a Residue-Based Pharmacophore Approach to Identify Cognate Protein Ligands in the Immunoglobulin Superfamily. PMID:27889206
An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes. PMID:27882922
Phylogenetic Diversity of Koala Retrovirus within a Wild Koala Population. PMID:27881645
Toward a new paradigm of DNA writing using a massively parallel sequencing platform and degenerate oligonucleotide. PMID:27876825
Plastid: nucleotide-resolution analysis of next-generation sequencing and genomics data. PMID:27875984
The impact of transposable elements on mammalian development. PMID:27875251
Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family. PMID:27867385
Regulatory activities of transposable elements: from conflicts to benefits. PMID:27867194
From profiles to function in epigenomics. PMID:27867193
Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint. PMID:27861980
The Role of Next-Generation Sequencing in Enabling Personalized Oncology Therapy. PMID:27860319
Gene Therapy for Metabolic Diseases. PMID:27853673
Non-coding RNAs match the deleted genomic regions in humans. PMID:27853310
CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening. PMID:27842490
False positives and false negatives measure less than 0.001% in labeling ssDNA with osmium tetroxide 2,2'-bipyridine. PMID:27826518
Regulation of disease-associated gene expression in the 3D genome. PMID:27826147
A Method for the Annotation of Functional Similarities of Coding DNA Sequences: the Case of a Populated Cluster of Transmembrane Proteins. PMID:27812751
The PARA-suite: PAR-CLIP specific sequence read simulation and processing. PMID:27812418
Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome. PMID:27798693
Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance. PMID:27791198
Genetics of rheumatoid arthritis: GWAS and beyond. PMID:27790002
Computational pan-genomics: status, promises and challenges. PMID:27769991
Sequencing and de novo assembly of the Asian gypsy moth transcriptome using the Illumina platform. PMID:27768153
Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models. PMID:27766308
A natural barrier to lateral gene transfer from prokaryotes to eukaryotes revealed from genomes: the 70 % rule. PMID:27751184
Epigenetic Aspects of Systemic Lupus Erythematosus. PMID:27747498
SVA retrotransposons as potential modulators of neuropeptide gene expression. PMID:27743609
Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification. PMID:27728778
Genome sequence of the basal haplorrhine primate Tarsius syrichta reveals unusual insertions. PMID:27708261
Identification and Characterization of Small Noncoding RNAs in Genome Sequences of the Edible Fungus Pleurotus ostreatus. PMID:27703969
OAHG: an integrated resource for annotating human genes with multi-level ontologies. PMID:27703231
LINEs between Species: Evolutionary Dynamics of LINE-1 Retrotransposons across the Eukaryotic Tree of Life. PMID:27702814
The Hoops, Hopes, and Hypes of Human Microbiome Research. PMID:27698620
An Ecological Framework of the Human Virome Provides Classification of Current Knowledge and Identifies Areas of Forthcoming Discovery. PMID:27698618
Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation. PMID:27697832
Elements in the Development of a Production Process for Modified Vaccinia Virus Ankara. PMID:27694766
Impact of the Autism-Associated Long Noncoding RNA MSNP1AS on Neuronal Architecture and Gene Expression in Human Neural Progenitor Cells. PMID:27690106
Laboratory Medicine in the Scope of Proteomics and Genomics. PMID:27683374
Reconstructing Demography and Social Behavior During the Neolithic Expansion from Genomic Diversity Across Island Southeast Asia. PMID:27683274
The possible roles of B-cell novel protein-1 (BCNP1) in cellular signalling pathways and in cancer. PMID:27680505
Advances in diagnostics for transplant rejection. PMID:27677432
Cervantes and Quijote protect heterochromatin from aberrant recombination and lead the way to the nuclear periphery. PMID:27673416
Chocó, Colombia: a hotspot of human biodiversity. PMID:27668076
Antisense Oligonucleotides Modulating Activation of a Nonsense-Mediated RNA Decay Switch Exon in the ATM Gene. PMID:27658045
Endogenous retroviruses mobilized during friend murine leukemia virus infection. PMID:27657834
Computational Evaluation of the Strict Master and Random Template Models of Endogenous Retrovirus Evolution. PMID:27649303
Omics-Based Strategies in Precision Medicine: Toward a Paradigm Shift in Inborn Errors of Metabolism Investigations. PMID:27649151
Oxford Nanopore MinION Sequencing and Genome Assembly. PMID:27646134
Heterochromatic histone modifications at transposons in Xenopus tropicalis embryos. PMID:27639284
Annotating the Function of the Human Genome with Gene Ontology and Disease Ontology. PMID:27635398
The Flow of the Gibbon LAVA Element Is Facilitated by the LINE-1 Retrotransposition Machinery. PMID:27635049
Selection on Position of Nonsense Codons in Introns. PMID:27630196
Identifying Nuclear Matrix-Attached DNA Across the Genome. PMID:27627025
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma. PMID:27625374
Technological advances in precision medicine and drug development. PMID:27622214
Great expectations - Epigenetics and the meandering path from bench to bedside. PMID:27621117
The 2016 Lasker~Koshland Special Achievement Award recognizes Bruce Alberts' lifelong dedication to research, policy, and education. PMID:27620537
De novo sequencing, assembly and analysis of eight different transcriptomes from the Malayan pangolin. PMID:27618997
Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing. PMID:27617755
Non-alcoholic fatty liver and the gut microbiota. PMID:27617201
Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes. PMID:27613107
Whole Genome Mapping with Feature Sets from High-Throughput Sequencing Data. PMID:27611682
Human Contamination in Public Genome Assemblies. PMID:27611326
Current Status of Long Non-Coding RNAs in Human Breast Cancer. PMID:27608009
A Retrospective Analysis of Precision Medicine Outcomes in Patients With Advanced Cancer Reveals Improved Progression-Free Survival Without Increased Health Care Costs. PMID:27601506
Silencing transposable elements in the Drosophila germline. PMID:27600679
Strategies for Genomic and Proteomic Profiling of Cancers. PMID:27594925
Discrepancies between human DNA, mRNA and protein reference sequences and their relation to single nucleotide variants in the human population. PMID:27589963
The function of homeobox genes and lncRNAs in cancer. PMID:27588114
ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells. PMID:27582018
Identifying wrong assemblies in de novo short read primary sequence assembly contigs. PMID:27581937
Role of pharmacogenetics in public health and clinical health care: a SWOT analysis. PMID:27577547
Regulation of CTNNB1 signaling in gastric cancer and stem cells. PMID:27574551
Circular RNAs: Unexpected outputs of many protein-coding genes. PMID:27571848
The science commons in health research: structure, function, and value. PMID:27570367
Tumor Touch Imprints as Source for Whole Genome Analysis of Neuroblastoma Tumors. PMID:27560999
An Optimal Seed Based Compression Algorithm for DNA Sequences. PMID:27555868
In silico identification of lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5. PMID:27553855
A preliminary review of influential works in data-driven discovery. PMID:27540499
Improving the Flexibility of RNA-Seq Data Analysis Pipelines. PMID:27536420
The Astrobiology Primer v2.0. PMID:27532777
Inference of Ancestral Recombination Graphs through Topological Data Analysis. PMID:27532298
A Crystallographic Examination of Predisposition versus Preorganization in de Novo Designed Metalloproteins. PMID:27532255
Detection of cis- and trans-acting Factors in DNA Structure-Induced Genetic Instability Using In silico and Cellular Approaches. PMID:27532010
Exploring cancer genomic data from the cancer genome atlas project. PMID:27530686
The Ribonuclease A Superfamily in Humans: Canonical RNases as the Buttress of Innate Immunity. PMID:27527162
Restricting retrotransposons: a review. PMID:27525044
Benchmarking computational tools for polymorphic transposable element detection. PMID:27524380
Structure and regulation of human troponin genes. PMID:27520667
IRWRLDA: improved random walk with restart for lncRNA-disease association prediction. PMID:27517318
Pharmacometabolomics informs Pharmacogenomics. PMID:27516730
Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers. PMID:27513638
Beyond Endometriosis Genome-Wide Association Study: From Genomics to Phenomics to the Patient. PMID:27513026
Transposable elements and miRNA: Regulation of genomic stability and plasticity. PMID:27511122
The transposable element environment of human genes is associated with histone and expression changes in cancer. PMID:27506777
The Role of Retrotransposons in Gene Family Expansions in the Human and Mouse Genomes. PMID:27503295
Genome-wide measures of DNA methylation in peripheral blood and the risk of urothelial cell carcinoma: a prospective nested case-control study. PMID:27490804
Pinpointing the vesper bat transposon revolution using the Miniopterus natalensis genome. PMID:27489570
Evolutionary dynamics of selfish DNA explains the abundance distribution of genomic subsequences. PMID:27488939
Imagining Sisyphus happy: DNA barcoding and the unnamed majority. PMID:27481781
A novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein. PMID:27481219
Multiscale Modeling of Cellular Epigenetic States: Stochasticity in Molecular Networks, Chromatin Folding in Cell Nuclei, and Tissue Pattern Formation of Cells. PMID:27480462
The bright side of dark matter: lncRNAs in cancer. PMID:27479746
Evidence of selection for an accessible nucleosomal array in human. PMID:27472913
In Vivo and In Vitro Genotoxic and Epigenetic Effects of Two Types of Cola Beverages and Caffeine: A Multiassay Approach. PMID:27471731
Existence of Two Distinct Infectious Endogenous Retroviruses in Domestic Cats and Their Different Strategies for Adaptation to Transcriptional Regulation. PMID:27466428
MR1 discovery. PMID:27464703
A Canonical Correlation Analysis of AIDS Restriction Genes and Metabolic Pathways Identifies Purine Metabolism as a Key Cooperator. PMID:27462363
Reprogramming, Circular Reasoning and Self versus Non-self: One-Stop Shopping with RNA Editing. PMID:27458478
Tissue homogeneity requires inhibition of unequal gene silencing during development. PMID:27458132
Aberrant DNA methylation reprogramming in bovine SCNT preimplantation embryos. PMID:27456302
Transcriptomic analyses of the radiation response in head and neck squamous cell carcinoma subclones with different radiation sensitivity: time-course gene expression profiles and gene association networks. PMID:27455841
Splicing variants of ADAR2 and ADAR2-mediated RNA editing in glioma. PMID:27446352
Expression of evolutionarily novel genes in tumors. PMID:27437030
Liquid biopsy in patients with pancreatic cancer: Circulating tumor cells and cell-free nucleic acids. PMID:27433079
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs. PMID:27431325
LncRNAs in pancreatic cancer. PMID:27429196
APOBEC3DE Inhibits LINE-1 Retrotransposition by Interacting with ORF1p and Influencing LINE Reverse Transcriptase Activity. PMID:27428332
On the pathogenesis of insulin-dependent diabetes mellitus: the role of microbiota. PMID:27421719
Zinc finger proteins in cancer progression. PMID:27411336
Transfer of DNA from Bacteria to Eukaryotes. PMID:27406565
CTRL+INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome. PMID:27402545
Novel Insights into Chromosome Evolution in Birds, Archosaurs, and Reptiles. PMID:27401172
Chromatin variation associated with liver metabolism is mediated by transposable elements. PMID:27398095
Preferential Protection of Genetic Fidelity within Open Chromatin by the Mismatch Repair Machinery. PMID:27382058
The Grand Challenge of Characterizing Ribonucleoprotein Networks. PMID:27376072
Comments and General Discussion on "The Anatomical Problem Posed by Brain Complexity and Size: A Potential Solution". PMID:27375436
[Treat to target and personalized medicine (precision medicine)]. PMID:27365026
Unraveling the message: insights into comparative genomics of the naked mole-rat. PMID:27364349
Comprehensive analysis of lncRNAs microarray profile and mRNA-lncRNA co-expression in oncogenic HPV-positive cervical cancer cell lines. PMID:27363024
Reverse transcriptase and intron number evolution. PMID:27358863
Analysis of tandem gene copies in maize chromosomal regions reconstructed from long sequence reads. PMID:27354512
Inherited platelet disorders: Insight from platelet genomics using next-generation sequencing. PMID:27348543
Long non-coding RNAs and complex diseases: from experimental results to computational models. PMID:27345524
Mitochondrial Epigenetics and Environmental Exposure. PMID:27344144
Integrated small copy number variations and epigenome maps of disorders of sex development. PMID:27340555
The second decade of 3C technologies: detailed insights into nuclear organization. PMID:27340173
Goodbye genome paper, hello genome report: the increasing popularity of 'genome announcements' and their impact on science. PMID:27339634
The value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancers. PMID:27338857
Nothing in Evolution Makes Sense Except in the Light of Genomics: Read-Write Genome Evolution as an Active Biological Process. PMID:27338490
MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity. PMID:27329728
Mammal madness: is the mammal tree of life not yet resolved? PMID:27325836
Inferring species divergence times using pairwise sequential Markovian coalescent modelling and low-coverage genomic data. PMID:27325835
IntNetLncSim: an integrative network analysis method to infer human lncRNA functional similarity. PMID:27323856
FMLNCSIM: fuzzy measure-based lncRNA functional similarity calculation model. PMID:27322210
Computational Tools for Stem Cell Biology. PMID:27318512
Repetitive element hypermethylation in multiple sclerosis patients. PMID:27317098
Polymorphic Alu Insertion/Deletion in Different Caste and Tribal Populations from South India. PMID:27315142
The Impact of Evolutionary Driving Forces on Human Complex Diseases: A Population Genetics Approach. PMID:27313952
Evaluation of Bioinformatic Programmes for the Analysis of Variants within Splice Site Consensus Regions. PMID:27313609
Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis. PMID:27309962
The Epithelial-to-Mesenchymal Transition (EMT), a Particular Case. PMID:27308335
phRAIDER: Pattern-Hunter based Rapid Ab Initio Detection of Elementary Repeats. PMID:27307619
Prediction of ribosome footprint profile shapes from transcript sequences. PMID:27307616
DMET™ (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine. PMID:27304055
Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research. PMID:27297499
PiggyBac transposon-based polyadenylation-signal trap for genome-wide mutagenesis in mice. PMID:27292714
Selection pressure on human STR loci and its relevance in repeat expansion disease. PMID:27290643
The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery. PMID:27279102
Ancient DNA and human history. PMID:27274045
De novo assembly and characterization of the Chinese three-keeled pond turtle (Mauremys reevesii) transcriptome: presence of longevity-related genes. PMID:27257545
CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases. PMID:27250031
The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and Survival of Cells. PMID:27246850
Genome stability versus transcript diversity. PMID:27246512
Global methylation, oxidative stress, and relative telomere length in biliary atresia patients. PMID:27243754
New Trends in Aryl Hydrocarbon Receptor Biology. PMID:27243009
Links between Human LINE-1 Retrotransposons and Hepatitis Virus-Related Hepatocellular Carcinoma. PMID:27242996
ArthropodaCyc: a CycADS powered collection of BioCyc databases to analyse and compare metabolism of arthropods. PMID:27242037
Lineage-specific genomics: Frequent birth and death in the human genome: The human genome contains many lineage-specific elements created by both sequence and functional turnover. PMID:27231054
LncRNApred: Classification of Long Non-Coding RNAs and Protein-Coding Transcripts by the Ensemble Algorithm with a New Hybrid Feature. PMID:27228152
Decoding transcriptional enhancers: Evolving from annotation to functional interpretation. PMID:27224938
Clinical genomics: from a truly personal genome viewpoint. PMID:27221143
Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end. PMID:27220521
Prenatal Air Pollution Exposures, DNA Methyl Transferase Genotypes, and Associations with Newborn LINE1 and Alu Methylation and Childhood Blood Pressure and Carotid Intima-Media Thickness in the Children's Health Study. PMID:27219456
DNA methylation by DNMT1 and DNMT3b methyltransferases is driven by the MUC1-C oncoprotein in human carcinoma cells. PMID:27212035
Identification of human RNA editing sites: A historical perspective. PMID:27208508
The Brugada Syndrome: A Rare Arrhythmia Disorder with Complex Inheritance. PMID:27200363
Retroviral DNA Integration. PMID:27198982
Endogenous Transposase Source in Human Cells Mobilizes piggyBac Transposons. PMID:27198853
A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. PMID:27197217
Challenges of Identifying Clinically Actionable Genetic Variants for Precision Medicine. PMID:27195526
X-Linked Candidate Genes for a Ciliopathy-Like Disorder. PMID:27194972
Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution. PMID:27189538
LTR12 promoter activation in a broad range of human tumor cells by HDAC inhibition. PMID:27172897
P53 and the defenses against genome instability caused by transposons and repetitive elements. PMID:27172878
Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis. PMID:27167177
Genomic Approaches to Zebrafish Cancer. PMID:27165352
CNS repair and axon regeneration: Using genetic variation to determine mechanisms. PMID:27163547
Next-generation sequencing-based detection of germline L1-mediated transductions. PMID:27161561
Transposable elements in the mammalian embryo: pioneers surviving through stealth and service. PMID:27161170
Genomic analysis of mouse VL30 retrotransposons. PMID:27158269
Roles for retrotransposon insertions in human disease. PMID:27158268
What are We Learning and What Can We Learn from the Human Oral Microbiome Project? PMID:27152251
The potential for liquid biopsies in the precision medical treatment of breast cancer. PMID:27144060
The Dark Side of Cell Fusion. PMID:27136533
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch. PMID:27136077
Redundans: an assembly pipeline for highly heterozygous genomes. PMID:27131372
Genes and Small RNA Transcripts Exhibit Dosage-Dependent Expression Pattern in Maize Copy-Number Alterations. PMID:27129738
A Protein Domain and Family Based Approach to Rare Variant Association Analysis. PMID:27128313
piR-651 and its function in 95-D lung cancer cells. PMID:27123245
Next-Generation Sequencing in the Genetics of Human Atrial Fibrillation. PMID:27122724
Generation, Characterization and Application of Antibodies Directed against HERV-H Gag Protein in Colorectal Samples. PMID:27119520
Metabolomics in epidemiology: from metabolite concentrations to integrative reaction networks. PMID:27118561
Challenges, Solutions, and Quality Metrics of Personal Genome Assembly in Advancing Precision Medicine. PMID:27110816
Non-negligible Occurrence of Errors in Gender Description in Public Data Sets. PMID:27103889
Application of whole genome shotgun sequencing for detection and characterization of genetically modified organisms and derived products. PMID:27100228
The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations. PMID:27099633
Alu SINE analyses of 3,000-year-old human skeletal remains: a pilot study. PMID:27096009
Exosomes: The Link between GPCR Activation and Metastatic Potential? PMID:27092178
Using an integrative approach to investigate the evolution of behaviour. PMID:27087846
Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved. PMID:27084945
Epigenetic regulation of bone cells. PMID:27082893
iJGVD: an integrative Japanese genome variation database based on whole-genome sequencing. PMID:27081555
Identification of novel exonic mobile element insertions in epithelial ovarian cancers. PMID:27081539
Evolution of Epigenetic Regulation in Vertebrate Genomes. PMID:27080453
Incidentalome from Genomic Sequencing: A Barrier to Personalized Medicine? PMID:27077130
Stress out the LINEs. PMID:27066303
The challenge of ORF1p phosphorylation: Effects on L1 activity and its host. PMID:27066302
Anchored pseudo-de novo assembly of human genomes identifies extensive sequence variation from unmapped sequence reads. PMID:27061184
Polymorphic tandem repeats within gene promoters act as modifiers of gene expression and DNA methylation in humans. PMID:27060133
23andMe: a new two-sided data-banking market model. PMID:27059184
What is translational bioinformatics? PMID:27054069
RNA Sequencing in Schizophrenia. PMID:27053919
Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing. PMID:27052831
Associations and prognostic implications of Eastern Cooperative Oncology Group performance status and tumoral LINE-1 methylation status in stage III colon cancer patients. PMID:27051466
Retrotransposon-associated long non-coding RNAs in mice and men. PMID:27044413
Active recombinant Tol2 transposase for gene transfer and gene discovery applications. PMID:27042235
No evidence for extensive horizontal gene transfer in the genome of the tardigrade Hypsibius dujardini. PMID:27035985
Alu methylation serves as a biomarker for non-invasive diagnosis of glioma. PMID:27028997
ILNCSIM: improved lncRNA functional similarity calculation model. PMID:27028993
Immune responses to endogenous retroelements: taking the bad with the good. PMID:27026073
LINE-1 distribution in six rodent genomes follow a species-specific pattern. PMID:27019429
Natural Selection and Genetic Diversity in the Butterfly Heliconius melpomene. PMID:27017626
Post-Transcriptional Control of LINE-1 Retrotransposition by Cellular Host Factors in Somatic Cells. PMID:27014690
To be an author. PMID:27011823
The Gene Expression Omnibus Database. PMID:27008011
Unraveling the evolutionary scenario of the hobo element in populations of Drosophila melanogaster and D. simulans in South America using the TPE repeats as markers. PMID:27007908
Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues. PMID:27003935
ROBO2 gene variants in children with primary nonsyndromic vesicoureteral reflux with or without renal hypoplasia/dysplasia. PMID:27002985
What Next in Schizophrenia Genetics for the Psychiatric Genomics Consortium? PMID:26994396
The Anolis Lizard Genome: An Amniote Genome without Isochores? PMID:26992416
Global Metabolic Reconstruction and Metabolic Gene Evolution in the Cattle Genome. PMID:26992093
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus. PMID:26989998
Horizontal transfer of β-carbonic anhydrase genes from prokaryotes to protozoans, insects, and nematodes. PMID:26983858
Suppressing H19 Modulates Tumorigenicity and Stemness in U251 and U87MG Glioma Cells. PMID:26983719
Next generation sequencing (NGS) database for tandem repeats with multiple pattern 2°-shaft multicore string matching. PMID:26981434
Recurrent Gene Duplication Diversifies Genome Defense Repertoire in Drosophila. PMID:26979388
Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells. PMID:26974322
Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing. PMID:26968627
Heavy Metal Exposure Influences Double Strand Break DNA Repair Outcomes. PMID:26966913
Identification and Analysis of the Role of Superoxide Dismutases Isoforms in the Pathogenesis of Paracoccidioides spp. PMID:26963091
Blood-Borne Pathogens: A Canadian Blood Services Centre for Innovation Symposium. PMID:26962008
Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals. PMID:26952212
Estrogen Receptor Alpha (ESR1) Single-Nucleotide Polymorphisms (SNPs) Affect Malignant Melanoma Susceptibility and Disease Course. PMID:26949342
Contemporary views on the genetics of anorexia nervosa. PMID:26944296
LINE retrotransposition and host DNA repair machinery. PMID:26942045
Alu elements and DNA double-strand break repair. PMID:26942043
Regulatory evolution of innate immunity through co-option of endogenous retroviruses. PMID:26941318
Forty years of The Selfish Gene are not enough. PMID:26936472
MaGuS: a tool for quality assessment and scaffolding of genome assemblies with Whole Genome Profiling™ Data. PMID:26936254
Modeling congenital disease and inborn errors of development in Drosophila melanogaster. PMID:26935104
Personalised cancer care: promises and challenges of targeted therapy. PMID:26933155
DNA methylation in human epigenomes depends on local topology of CpG sites. PMID:26932361
Gene Variant Databases and Sharing: Creating a Global Genomic Variant Database for Personalized Medicine. PMID:26931283
Mechanisms underlying structural variant formation in genomic disorders. PMID:26924765
Establishing gene models from the Pinus pinaster genome using gene capture and BAC sequencing. PMID:26922242
Transcriptome Analysis in Domesticated Species: Challenges and Strategies. PMID:26917953
Discovery of a new repeat family in the Callithrix jacchus genome. PMID:26916108
Retrotransposons as regulators of gene expression. PMID:26912865
Human genetic variation database, a reference database of genetic variations in the Japanese population. PMID:26911352
Atlas of Cryptic Genetic Relatedness Among 1000 Human Genomes. PMID:26907499
The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer. PMID:26904537
Ensembl comparative genomics resources. PMID:26896847
LEAP: L1 Element Amplification Protocol. PMID:26895063
Immunodetection of Human LINE-1 Expression in Cultured Cells and Human Tissues. PMID:26895059
LINE-1 Cultured Cell Retrotransposition Assay. PMID:26895052
DNA methylation variation of human-specific Alu repeats. PMID:26890526
A protein constructed de novo enables cell growth by altering gene regulation. PMID:26884172
Managing risks in drug discovery: reproducibility of published findings. PMID:26883784
Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor. PMID:26883630
Molecular features of cellular reprogramming and development. PMID:26883001
Unravelling the human genome-phenome relationship using phenome-wide association studies. PMID:26875678
A Biologist's Field Guide to Multiplexed Quantitative Proteomics. PMID:26873251
MetaSINEs: Broad Distribution of a Novel SINE Superfamily in Animals. PMID:26872770
A benchmark study on error-correction by read-pairing and tag-clustering in amplicon-based deep sequencing. PMID:26868371
Curated eutherian third party data gene data sets. PMID:26862561
The contribution of transposable elements to size variations between four teleost genomes. PMID:26862351
Biochemistry and physiology within the framework of the extended synthesis of evolutionary biology. PMID:26861860
Enrichment analysis of Alu elements with different spatial chromatin proximity in the human genome. PMID:26861146
Integrated cytogenetics and genomics analysis of transposable elements in the Nile tilapia, Oreochromis niloticus. PMID:26860923
Quantification of unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples. PMID:26859682
Feature co-localization landscape of the human genome. PMID:26854351
Graphene nanodevices for DNA sequencing. PMID:26839258
Decoding DNA, RNA and peptides with quantum tunnelling. PMID:26839257
When Medicine Meets Engineering-Paradigm Shifts in Diagnostics and Therapeutics. PMID:26835672
SncRNA (microRNA &snoRNA) opposite expression pattern found in multiple sclerosis relapse and remission is sex dependent. PMID:26831009
Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility. PMID:26818075
An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. PMID:26814573
Impact of host genetic polymorphisms on vaccine induced antibody response. PMID:26809773
Classification and characterization of human endogenous retroviruses; mosaic forms are common. PMID:26800882
Next-generation sequencing as an approach to dairy starter selection. PMID:26798445
detectMITE: A novel approach to detect miniature inverted repeat transposable elements in genomes. PMID:26795595
Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus. PMID:26795348
Human Endogenous Retroviruses as Pathogenic Factors in the Development of Schizophrenia. PMID:26793126
Infectious Entry Pathway Mediated by the Human Endogenous Retrovirus K Envelope Protein. PMID:26792739
Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace. PMID:26780094
Genomic landscapes of endogenous retroviruses unveil intricate genetics of conventional and genetically-engineered laboratory mouse strains. PMID:26779669
Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance. PMID:26779254
Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription Networks. PMID:26763983
Different Facets of Copy Number Changes: Permanent, Transient, and Adaptive. PMID:26755558
A Molecular Perspective on Procedures and Outcomes with Assisted Reproductive Technologies. PMID:26747835
Experimental methods to preserve male fertility and treat male factor infertility. PMID:26746133
Crossing the LINE Toward Genomic Instability: LINE-1 Retrotransposition in Cancer. PMID:26734601
Pathway Analysis: State of the Art. PMID:26733877
Diagnosis of D-Bifunctional Protein Deficiency through Whole-Genome Sequencing: Implications for Cost-Effective Care. PMID:26733776
In Silico Functional Annotation of Genomic Variation. PMID:26724722
Transposable element detection from whole genome sequence data. PMID:26719777
Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation. PMID:26716650
Insulated Foamy Viral Vectors. PMID:26715244
Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines. PMID:26714498
Gene therapy: progress and predictions. PMID:26702034
Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases. PMID:26691922
Horizontal functional gene transfer from bacteria to fishes. PMID:26691285
Comparing genetic variants detected in the 1000 genomes project with SNPs determined by the International HapMap Consortium. PMID:26690529
5th International ACC Symposium: The New Genetics of Benign Adrenocortical Neoplasia: Hyperplasias, Adenomas, and Their Implications for Progression into Cancer. PMID:26684645
A Small RNA-Based Immune System Defends Germ Cells against Mobile Genetic Elements. PMID:26681955
Somatic mosaicism: on the road to cancer. PMID:26678315
Estradiol differentially induces progesterone receptor isoforms expression through alternative promoter regulation in a mouse embryonic hypothalamic cell line. PMID:26676302
Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus. PMID:26675493
L1 retrotransposition requires rapid ORF1p oligomerization, a novel coiled coil-dependent property conserved despite extensive remodeling. PMID:26673717
Expressed Sequence Tags Analysis and Design of Simple Sequence Repeats Markers from a Full-Length cDNA Library in Perilla frutescens (L.). PMID:26664999
Circulating nucleic acids: a new class of physiological mobile genetic elements. PMID:26664710
Evolution of Nine Microsatellite Loci in the Fungus Fusarium oxysporum. PMID:26661928
Exercise-conditioned plasma attenuates nuclear concentrations of DNA methyltransferase 3B in human peripheral blood mononuclear cells. PMID:26660547
The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAs. PMID:26654912
Comparative genomic analysis of eutherian tumor necrosis factor ligand genes. PMID:26646413
Systems Genetic Validation of the SNP-Metabolite Association in Rice Via Metabolite-Pathway-Based Phenome-Wide Association Scans. PMID:26640468
Segmenting the Human Genome into Isochores. PMID:26640363
RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. PMID:26636579
Systematic identification and annotation of human methylation marks based on bisulfite sequencing methylomes reveals distinct roles of cell type-specific hypomethylation in the regulation of cell identity genes. PMID:26635396
Progress and challenges in bioinformatics approaches for enhancer identification. PMID:26634919
Metagenomic Classification Using an Abstraction Augmented Markov Model. PMID:26618474
Reverse transcriptase genes are highly abundant and transcriptionally active in marine plankton assemblages. PMID:26613339
Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring. PMID:26608942
microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases. PMID:26608596
The PsychENCODE project. PMID:26605881
Aquatic adaptation and the evolution of smell and taste in whales. PMID:26605054
Transcriptome networks in the mouse retina: An exon level BXD RI database. PMID:26604663
Multinational teams and diseconomies of scale in collaborative research. PMID:26601251
Evolution and Biological Roles of Alternative 3'UTRs. PMID:26597575
Transcriptomics of diapause in an isogenic self-fertilizing vertebrate. PMID:26597228
Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain. PMID:26590212
A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition. PMID:26585388
Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-κB Pathway. PMID:26584434
Ancestral Mutations Acquired in Refrex-1, a Restriction Factor against Feline Retroviruses, during its Cooption and Domestication. PMID:26581999
What might retrotransposons teach us about aging? PMID:26581630
Suppression of the Arboviruses Dengue and Chikungunya Using a Dual-Acting Group-I Intron Coupled with Conditional Expression of the Bax C-Terminal Domain. PMID:26580561
Transposable element polymorphisms recapitulate human evolution. PMID:26579215
Death of a dogma: eukaryotic mRNAs can code for more than one protein. PMID:26578573
KATZLDA: KATZ measure for the lncRNA-disease association prediction. PMID:26577439
Adaptive Evolution Coupled with Retrotransposon Exaptation Allowed for the Generation of a Human-Protein-Specific Coding Gene That Promotes Cancer Cell Proliferation and Metastasis in Both Haematological Malignancies and Solid Tumours: The Extraordinary Case of MYEOV Gene. PMID:26568894
Are Synonymous Sites in Primates and Rodents Functionally Constrained? PMID:26563252
Cross-Species Transmission and Differential Fate of an Endogenous Retrovirus in Three Mammal Lineages. PMID:26562410
The sequence of sequencers: The history of sequencing DNA. PMID:26554401
Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation. PMID:26553804
Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells. PMID:26550473
Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR-193b. PMID:26549028
Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions. PMID:26545598
Long noncoding RNAs in T lymphocytes. PMID:26538526
Gain of a New Exon by a Lineage-Specific Alu Element-Integration Event in the BCS1L Gene during Primate Evolution. PMID:26537194
Characteristics of α-Gal epitope, anti-Gal antibody, α1,3 galactosyltransferase and its clinical exploitation (Review). PMID:26531137
Genes and dental disorders. PMID:26527946
Cnidaria: fast, reference-free clustering of raw and assembled genome and transcriptome NGS data. PMID:26525298
Expression of young HERV-H loci in the course of colorectal carcinoma and correlation with molecular subtypes. PMID:26517682
Comparing the normalization methods for the differential analysis of Illumina high-throughput RNA-Seq data. PMID:26511205
CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors. PMID:26510915
Genome-wide evolutionary and functional analysis of the Equine Repetitive Element 1: an insertion in the myostatin promoter affects gene expression. PMID:26503543
Discovery and characterization of Alu repeat sequences via precise local read assembly. PMID:26503250
Clinical prospects of long noncoding RNAs as novel biomarkers and therapeutic targets in prostate cancer. PMID:26503110
Deciphering the Developmental Dynamics of the Mouse Liver Transcriptome. PMID:26496202
Evidence of Extensive Alternative Splicing in Post Mortem Human Brain HTT Transcription by mRNA Sequencing. PMID:26496077
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping. PMID:26492141
Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer. PMID:26489798
Regulation of PKR by RNA: formation of active and inactive dimers. PMID:26488609
PCR-Free Enrichment of Mitochondrial DNA from Human Blood and Cell Lines for High Quality Next-Generation DNA Sequencing. PMID:26488301
Comparison among three variant callers and assessment of the accuracy of imputation from SNP array data to whole-genome sequence level in chicken. PMID:26486989
Kuwaiti population subgroup of nomadic Bedouin ancestry-Whole genome sequence and analysis. PMID:26484159
Assessing quality standards for ChIP-seq and related massive parallel sequencing-generated datasets: When rating goes beyond avoiding the crisis. PMID:26484107
Third party annotation gene data set of eutherian lysozyme genes. PMID:26484105
Cardiac cAMP: production, hydrolysis, modulation and detection. PMID:26483685
Increased Transcript Complexity in Genes Associated with Chronic Obstructive Pulmonary Disease. PMID:26480348
Potential impact of gene regulatory mechanisms on the evolution of multicellularity in the volvocine algae. PMID:26479715
Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA. PMID:26474073
Transcriptome profile of liver at different physiological stages reveals potential mode for lipid metabolism in laying hens. PMID:26452545
Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing. PMID:26449678
The Fine LINE: Methylation Drawing the Cancer Landscape. PMID:26448926
Ten Simple Rules for Writing a Reply Paper. PMID:26448197
Expression profile of long non-coding RNAs in pancreatic cancer and their clinical significance as biomarkers. PMID:26447755
Stacked thin layers of metaphase chromatin explain the geometry of chromosome rearrangements and banding. PMID:26446309
Progress of cancer genomics. PMID:26445603
Genetics of Hearing Loss: Syndromic. PMID:26443487
Genetic variation and the de novo assembly of human genomes. PMID:26442640
LINE-1 activity as molecular basis for genomic instability associated with light exposure at night. PMID:26442182
Repetitive elements regulate circular RNA biogenesis. PMID:26442181
Drawing a fine line on endogenous retroelement activity. PMID:26442176
Endogenous retrovirus-mediated genomic variations in chimpanzees. PMID:26442175
An assay to monitor the activity of DNA transposition complexes yields a general quality control measure for transpositional recombination reactions. PMID:26442171
Assembly and characterization of novel Alu inserts detected from next-generation sequencing data. PMID:26442170
The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia. PMID:26439490
Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family. PMID:26435754
Alternative Splicing QTLs in European and African Populations. PMID:26430802
Genome-wide analysis of tandem repeats in Tribolium castaneum genome reveals abundant and highly dynamic tandem repeat families with satellite DNA features in euchromatic chromosomal arms. PMID:26428853
Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data. PMID:26423047
Ultra-fast local-haplotype variant calling using paired-end DNA-sequencing data reveals somatic mosaicism in tumor and normal blood samples. PMID:26420835
Present and future challenges of induced pluripotent stem cells. PMID:26416678
Next-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us? PMID:26404381
Chromosomal Rearrangements as Barriers to Genetic Homogenization between Archaic and Modern Humans. PMID:26399483
De novo sequencing and assembly analysis of transcriptome in the Sodom apple (Calotropis gigantea). PMID:26395839
Group-based variant calling leveraging next-generation supercomputing for large-scale whole-genome sequencing studies. PMID:26395405
Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength. PMID:26392272
A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity. PMID:26384429
The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression. PMID:26382853
Bioinformatics in Africa: The Rise of Ghana? PMID:26378921
Exploration of Deregulated Long Non-Coding RNAs in Association with Hepatocarcinogenesis and Survival. PMID:26378581
The genome of the vervet (Chlorocebus aethiops sabaeus). PMID:26377836
Donkey genome and insight into the imprinting of fast karyotype evolution. PMID:26373886
miR-128 represses L1 retrotransposition by binding directly to L1 RNA. PMID:26367248
Adapting capillary gel electrophoresis as a sensitive, high-throughput method to accelerate characterization of nucleic acid metabolic enzymes. PMID:26365239
Short interspersed DNA elements and miRNAs: a novel hidden gene regulation layer in zebrafish? PMID:26363800
The Bottleneck in Genetic Testing. PMID:26358106
Aberrant reduction of telomere repetitive sequences in plasma cell-free DNA for early breast cancer detection. PMID:26356673
Can a few non-coding mutations make a human brain? PMID:26350501
Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies. PMID:26349415
Genetic Susceptibility to Rhodococcus equi. PMID:26340305
Villain of Molecular Biology: Why are we not reproducible in research? PMID:26339478
EMSAR: estimation of transcript abundance from RNA-seq data by mappability-based segmentation and reclustering. PMID:26335049
LINE-1 in cancer: multifaceted functions and potential clinical implications. PMID:26334179
Utility of whole-genome sequencing for detection of newborn screening disorders in a population cohort of 1,696 neonates. PMID:26334177
Improving the Power of Structural Variation Detection by Augmenting the Reference. PMID:26322511
Sequence Analysis and Characterization of Active Human Alu Subfamilies Based on the 1000 Genomes Pilot Project. PMID:26319576
Next-generation sequencing: hype and hope for development of personalized radiation therapy? PMID:26316159
Recent advances in the study of active endogenous retrovirus envelope glycoproteins in the mammalian placenta. PMID:26311491
Visualizing genome and systems biology: technologies, tools, implementation techniques and trends, past, present and future. PMID:26309733
Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes. PMID:26300000
Structural and functional liaisons between transposable elements and satellite DNAs. PMID:26293606
Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. PMID:26292667
Tandem repeat variation in human and great ape populations and its impact on gene expression divergence. PMID:26290536
Evolutionary transitions in the Asteraceae coincide with marked shifts in transposable element abundance. PMID:26290182
The genomic landscape of human immune-mediated diseases. PMID:26290150
Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer. PMID:26279304
Onco-exaptation of an endogenous retroviral LTR drives IRF5 expression in Hodgkin lymphoma. PMID:26279299
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA. PMID:26278472
An Atypical AAA+ ATPase Assembly Controls Efficient Transposition through DNA Remodeling and Transposase Recruitment. PMID:26276634
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself. PMID:26275108
Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression. PMID:26274327
Making the case for chromatin profiling: a new tool to investigate the immune-regulatory landscape. PMID:26272294
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities. PMID:26261309
SINEUPs: A new class of natural and synthetic antisense long non-coding RNAs that activate translation. PMID:26259533
A Sparse Model Based Detection of Copy Number Variations From Exome Sequencing Data. PMID:26258935
Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases. PMID:26258142
Genome-wide profiling of DNA methylation reveals preferred sequences of DNMTs in hepatocellular carcinoma cells. PMID:26254611
Paradigm shifts in genomics through the FANTOM projects. PMID:26253466
SNP Formation Bias in the Murine Genome Provides Evidence for Parallel Evolution. PMID:26253317
Clinical exome sequencing in neurogenetic and neuropsychiatric disorders. PMID:26250888
GC-Content of Synonymous Codons Profoundly Influences Amino Acid Usage. PMID:26248983
'Cut from the same cloth': Shared microsatellite variants among cancers link to ectodermal tissues-neural tube and crest cells. PMID:26246470
A call for benchmarking transposable element annotation methods. PMID:26244060
Prenatal Programming and Toxicity (PPTOX) Introduction. PMID:26241073
Use of miRNAs in biofluids as biomarkers in dietary and lifestyle intervention studies. PMID:26233309
KLF/SP Transcription Factor Family Evolution: Expansion, Diversification, and Innovation in Eukaryotes. PMID:26232396
Big Data Analytics in Healthcare. PMID:26229957
Transcription factors, chromatin proteins and the diversification of Hemiptera. PMID:26226651
A Genome-Wide Landscape of Retrocopies in Primate Genomes. PMID:26224704
The role of Alu elements in the cis-regulation of RNA processing. PMID:26223268
Long Non-coding RNA ANRIL and Polycomb in Human Cancers and Cardiovascular Disease. PMID:26220772
Circadian disruption and breast cancer: an epigenetic link? PMID:26220712
Genomic medicine in gastroenterology: A new approach or a new specialty? PMID:26217074
Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers. PMID:26216839
Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes. PMID:26216318
An open ecosystem engagement strategy through the lens of global food safety. PMID:26213614
Glioma Association and Balancing Selection of ZFPM2. PMID:26207917
Red: an intelligent, rapid, accurate tool for detecting repeats de-novo on the genomic scale. PMID:26206263
MI-PVT: A Tool for Visualizing the Chromosome-Centric Human Proteome. PMID:26204236
Cell therapies and regenerative medicine. PMID:26202498
Molecular Testing in Myelodysplastic Syndromes for the Practicing Oncologist: Will the Progress Fulfill the Promise? PMID:26194858
Marsupials and monotremes possess a novel family of MHC class I genes that is lost from the eutherian lineage. PMID:26194104
Traumatic spinal cord injury in mice with human immune systems. PMID:26193167
Regulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genes. PMID:26190021
Utility and limitations of exome sequencing as a genetic diagnostic tool for conditions associated with pediatric sudden cardiac arrest/sudden cardiac death. PMID:26187847
LINE-1 Retroelements Get ZAPped! PMID:26182081
Harnessing Pandemonium: The Clinical Implications of Tumor Heterogeneity in Ovarian Cancer. PMID:26175968
The NIH BD2K center for big data in translational genomics. PMID:26174866
Defining "mutation" and "polymorphism" in the era of personal genomics. PMID:26173390
Regulation of human MAPT gene expression. PMID:26170022
Long non-coding RNAs in innate and adaptive immunity. PMID:26166759
Biodiversity Meets Neuroscience: From the Sequencing Ship (Ship-Seq) to Deciphering Parallel Evolution of Neural Systems in Omic's Era. PMID:26163680
Detection of Genomic Structural Variants from Next-Generation Sequencing Data. PMID:26161383
Evaluation of BLAST-based edge-weighting metrics used for homology inference with the Markov Clustering algorithm. PMID:26160651
Long Noncoding RNA in Digestive Tract Cancers: Function, Mechanism, and Potential Biomarker. PMID:26156325
Read count-based method for high-throughput allelic genotyping of transposable elements and structural variants. PMID:26153459
Label-free DNA sequencing using Millikan detection. PMID:26151683
Comparison of Gene Coexpression Profiles and Construction of Conserved Gene Networks to Find Functional Modules. PMID:26147120
An improved understanding of cancer genomics through massively parallel sequencing. PMID:26146607
Revisiting disease genes based on whole-exome sequencing in consanguineous populations. PMID:26141664
RNA Structures as Mediators of Neurological Diseases and as Drug Targets. PMID:26139368
DNAseq Workflow in a Diagnostic Context and an Example of a User Friendly Implementation. PMID:26137478
Hydra as a tractable, long-lived model system for senescence. PMID:26136619
Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia. PMID:26132940
High-throughput RNA sequencing reveals structural differences of orthologous brain-expressed genes between western lowland gorillas and humans. PMID:26132897
Assembly and diploid architecture of an individual human genome via single-molecule technologies. PMID:26121404
Quantification of SAHA-Dependent Changes in Histone Modifications Using Data-Independent Acquisition Mass Spectrometry. PMID:26120868
The diversification of PHIS transposon superfamily in eukaryotes. PMID:26120370
Epigenetic signaling in schizophrenia. PMID:26120009
The Role of Transposable Elements in the Origin and Evolution of MicroRNAs in Human. PMID:26115450
Causes of genome instability: the effect of low dose chemical exposures in modern society. PMID:26106144
P Transposable Elements in Drosophila and other Eukaryotic Organisms. PMID:26104714
The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes. PMID:26104698
Np9, a cellular protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin ligase MDM2. PMID:26103464
Engineered CRISPR-Cas9 nucleases with altered PAM specificities. PMID:26098369
Connecting the speckles: Splicing kinases and their role in tumorigenesis and treatment response. PMID:26098145
Associations between genetic variation in one-carbon metabolism and LINE-1 DNA methylation in histologically normal breast tissues. PMID:26090795
RNA Sequencing for Identification of Differentially Expressed Noncoding Transcripts during Adipogenic Differentiation of Adipose-Derived Stromal Cells. PMID:26090763
Normalization of Complete Genome Characteristics: Application to Evolution from Primitive Organisms to Homo sapiens. PMID:26085808
Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets. PMID:26082843
Mx1 and Mx2 key antiviral proteins are surprisingly lost in toothed whales. PMID:26080416
Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex. PMID:26076492
Breaking bad: The mutagenic effect of DNA repair. PMID:26073774
The epigenetics of aging and neurodegeneration. PMID:26072273
Advances in long noncoding RNAs: identification, structure prediction and function annotation. PMID:26072035
Unbalanced translocations arise from diverse mutational mechanisms including chromothripsis. PMID:26070663
Coding Microsatellite Frameshift Mutations Accumulate in Atherosclerotic Carotid Artery Lesions: Evaluation of 26 Cases and Literature Review. PMID:26070012
Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens. PMID:26068926
Preferential Amplification of Pathogenic Sequences. PMID:26067233
Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity. PMID:26061969
Gene therapy for cancer: present status and future perspective. PMID:26056594
Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells. PMID:26056301
A general concept for consistent documentation of computational analyses. PMID:26055099
Differential Epigenetic Effects of Atmospheric Cold Plasma on MCF-7 and MDA-MB-231 Breast Cancer Cells. PMID:26042423
Emerging applications of read profiles towards the functional annotation of the genome. PMID:26042150
Cardiovascular genetics: technological advancements and applicability for dilated cardiomyopathy. PMID:26031632
Molecular epigenetic switches in neurodevelopment in health and disease. PMID:26029068
Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death. PMID:26024393
Genome-Wide Search Identifies 1.9 Mb from the Polar Bear Y Chromosome for Evolutionary Analyses. PMID:26019166
The human transmembrane proteome. PMID:26018427
A statistical framework to predict functional non-coding regions in the human genome through integrated analysis of annotation data. PMID:26015273
Targeted Capture of Phylogenetically Informative Ves SINE Insertions in Genus Myotis. PMID:26014613
Assembling large genomes with single-molecule sequencing and locality-sensitive hashing. PMID:26006009
De novo assembly of a haplotype-resolved human genome. PMID:26006006
The cancer cell map initiative: defining the hallmark networks of cancer. PMID:26000852
High-throughput sequencing technologies. PMID:26000844
Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR. PMID:26000843
The road from next-generation sequencing to personalized medicine. PMID:26000024
The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer. PMID:25997618
Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites. PMID:25995269
The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. PMID:25992231
Differential SINE evolution in vesper and non-vesper bats. PMID:25991928
A low-latency, big database system and browser for storage, querying and visualization of 3D genomic data. PMID:25990738
Roles of solvent accessibility and gene expression in modeling protein sequence evolution. PMID:25987828
Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. PMID:25986534
A seven-gene CpG-island methylation panel predicts breast cancer progression. PMID:25986046
LINEs in mice: features, families, and potential roles in early development. PMID:25975894
Epigenetics and pharmacology. PMID:25966315
Division of labor between IRF1 and IRF2 in regulating different stages of transcriptional activation in cellular antiviral activities. PMID:25960866
The hidden side of unstable DNA repeats: Mutagenesis at a distance. PMID:25956860
Genome-wide comparison of Asian and African rice reveals high recent activity of DNA transposons. PMID:25954322
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition. PMID:25951186
Haplotype-resolved genome sequencing: experimental methods and applications. PMID:25948246
Functional significance of the sex chromosomes during spermatogenesis. PMID:25948089
The renaissance of developmental biology. PMID:25946596
Advances in genetics and genomics: use and limitations in achieving malaria elimination goals. PMID:25943157
Initial description of primate-specific cystine-knot Prometheus genes and differential gene expansions of D-dopachrome tautomerase genes. PMID:25941635
Obstruction of adaptation in diploids by recessive, strongly deleterious alleles. PMID:25941393
Genome-wide amplification of proviral sequences reveals new polymorphic HERV-K(HML-2) proviruses in humans and chimpanzees that are absent from genome assemblies. PMID:25927962
Utility of proteomics in obstetric disorders: a review. PMID:25926758
Functional classification of 15 million SNPs detected from diverse chicken populations. PMID:25926514
Alu-mediated diverse and complex pathogenic copy-number variants within human chromosome 17 at p13.3. PMID:25908615
Identification, Diversity and Evolution of MITEs in the Genomes of Microsporidian Nosema Parasites. PMID:25898273
Do larger genomes contain more diverse transposable elements? PMID:25896861
piRNA involvement in genome stability and human cancer. PMID:25895683
Sustained proliferation in cancer: Mechanisms and novel therapeutic targets. PMID:25892662
Structural variation mutagenesis of the human genome: Impact on disease and evolution. PMID:25892534
Laser capture microdissection: Big data from small samples. PMID:25892148
Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan. PMID:25887915
Unraveling the 3D genome: genomics tools for multiscale exploration. PMID:25887733
Prediction of host - pathogen protein interactions between Mycobacterium tuberculosis and Homo sapiens using sequence motifs. PMID:25887594
Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals. PMID:25887476
CopywriteR: DNA copy number detection from off-target sequence data. PMID:25887352
Melatonin: an inhibitor of breast cancer. PMID:25876649
A simple strategy for reducing false negatives in calling variants from single-cell sequencing data. PMID:25876174
Evolution of genetic techniques: past, present, and beyond. PMID:25874212
AID to overcome the limitations of genomic information by introducing somatic DNA alterations. PMID:25873751
Seeking a roadmap toward neuroepigenetics. PMID:25856479
Long noncoding RNAs in cardiac development and ageing. PMID:25855606
New bioinformatic tool for quick identification of functionally relevant endogenous retroviral inserts in human genome. PMID:25853282
Evidence for Natural Selection in Nucleotide Content Relationships Based on Complete Mitochondrial Genomes: Strong Effect of Guanine Content on Separation between Terrestrial and Aquatic Vertebrates. PMID:25853054
An epigenetic hypothesis for the genomic memory of pain. PMID:25852480
A network of RNA and protein interactions in Fronto Temporal Dementia. PMID:25852467
Biochemical functional predictions for protein structures of unknown or uncertain function. PMID:25848497
The Human Alzheimer Disease Project: A New Call to Arms. PMID:25844883
Temporal and spatial rearrangements of a repetitive element array on C57BL/6J mouse genome. PMID:25839092
The mechanism of ageing: primary role of transposable elements in genome disintegration. PMID:25837999
Progress and challenges in developing metabolic footprints from diet in human gut microbial cometabolism. PMID:25833886
Non-coding RNAs and hypertension-unveiling unexpected mechanisms of hypertension by the dark matter of the genome. PMID:25828869
Whole-exome sequencing and its impact in hereditary hearing loss. PMID:25825321
Comprehensive data resources and analytical tools for pathological association of aminoacyl tRNA synthetases with cancer. PMID:25824651
The future of human cerebral cartography: a novel approach. PMID:25823868
Accurate typing of short tandem repeats from genome-wide sequencing data and its applications. PMID:25823460
Non-coding RNA: a new frontier in regulatory biology. PMID:25821635
Mobilization of LINE-1 in irradiated mammary gland tissue may potentially contribute to low dose radiation-induced genomic instability. PMID:25821563
Activation of an endogenous retrovirus-associated long non-coding RNA in human adenocarcinoma. PMID:25821520
Epigenetic regulation of intragenic transposable elements impacts gene transcription in Arabidopsis thaliana. PMID:25813042
Impacts of a biobank: Bridging the gap in translational cancer medicine. PMID:25810570
Long Non-Coding RNA Expression during Aging in the Human Subependymal Zone. PMID:25806019
Genome-wide transcript profiling reveals novel breast cancer-associated intronic sense RNAs. PMID:25798919
LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines. PMID:25798839
Personal genomes, quantitative dynamic omics and personalized medicine. PMID:25798291
Inter-locus as well as intra-locus heterogeneity in LINE-1 promoter methylation in common human cancers suggests selective demethylation pressure at specific CpGs. PMID:25798207
DNA methylation dynamics in muscle development and disease. PMID:25798107
Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes. PMID:25789975
Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selection. PMID:25786870
Human endogenous retrovirus group E and its involvement in diseases. PMID:25785516
Expression of multiple horizontally acquired genes is a hallmark of both vertebrate and invertebrate genomes. PMID:25785303
Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds. PMID:25781995
The Role of Regulatory Agencies and Intellectual Property: Part I. PMID:25775921
Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage. PMID:25774044
Prognostic significance of promoter CpG island hypermethylation and repetitive DNA hypomethylation in stage I lung adenocarcinoma. PMID:25772390
Cancer metabolism: strategic diversion from targeting cancer drivers to targeting cancer suppliers. PMID:25767677
Evolutionary patterns of DNA base composition and correlation to polymorphisms in DNA repair systems. PMID:25765652
Sequence and analysis of a whole genome from Kuwaiti population subgroup of Persian ancestry. PMID:25765185
U6 snRNA Pseudogenes: Markers of Retrotransposition Dynamics in Mammals. PMID:25761766
The contribution of alu elements to mutagenic DNA double-strand break repair. PMID:25761216
Evaluating historical candidate genes for schizophrenia. PMID:25754081
Landscape of insertion polymorphisms in the human genome. PMID:25745018
On bioinformatic resources. PMID:25743088
Whole genome analysis of a Vietnamese trio. PMID:25740146
SVA retrotransposition in exon 6 of the coagulation factor IX gene causing severe hemophilia B. PMID:25739383
Epigenetic Mechanisms of Serotonin Signaling. PMID:25734378
Transcriptional activity of human endogenous retroviruses in human peripheral blood mononuclear cells. PMID:25734056
Toward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: principles, hopes, and challenges. PMID:25733832
The effects of chromatin organization on variation in mutation rates in the genome. PMID:25732611
Mismatch repair during homologous and homeologous recombination. PMID:25731766
Type I interferon controls propagation of long interspersed element-1. PMID:25716322
terMITEs: miniature inverted-repeat transposable elements (MITEs) in the termite genome (Blattodea: Termitoidae). PMID:25711308
Genetic changes shaping the human brain. PMID:25710529
Computational prediction of molecular pathogen-host interactions based on dual transcriptome data. PMID:25705211
Genome architecture and its roles in human copy number variation. PMID:25705150
Genetics of Vascular Dementia. PMID:25705074
Pseudogene-derived lncRNAs: emerging regulators of gene expression. PMID:25699073
The genetic regulation of infant immune responses to vaccination. PMID:25699041
Methods in molecular cardiology: in silico cloning. PMID:25696371
Methods in molecular cardiology: microarray technology. PMID:25696214
Methods in molecular cardiology: DNA sequencing. PMID:25696079
The effect of life history on retroviral genome invasions. PMID:25692467
C2H2 zinc finger proteins greatly expand the human regulatory lexicon. PMID:25690854
Personalization of the immunosuppressive treatment in renal transplant recipients: the great challenge in "omics" medicine. PMID:25690039
The Genome 10K Project: a way forward. PMID:25689317
Biomarkers in Patients with Metastatic Breast Cancer and the PRAEGNANT Study Network. PMID:25684786
Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein. PMID:25671812
Embryonic stem cell specific "master" replication origins at the heart of the loss of pluripotency. PMID:25658386
Dispersal of an ancient retroposon in the TP53 promoter of Bovidae: phylogeny, novel mechanisms, and potential implications for cow milk persistency. PMID:25653076
Utilising the resources of the International Knockout Mouse Consortium: the Australian experience. PMID:25645994
A copy number variation map of the human genome. PMID:25645873
The aging clock and circadian control of metabolism and genome stability. PMID:25642238
The decline of human endogenous retroviruses: extinction and survival. PMID:25640971
Pure interstitial dup(6)(q22.31q22.31) - a case report. PMID:25637059
Exogenous enzymes upgrade transgenesis and genetic engineering of farm animals. PMID:25636347
The role of DNA insertions in phenotypic differentiation between humans and other primates. PMID:25635043
Evolutionary histories of transposable elements in the genome of the largest living marsupial carnivore, the Tasmanian devil. PMID:25633377
First insight into divergence, representation and chromosome distribution of reverse transcriptase fragments from L1 retrotransposons in peanut and wild relative species. PMID:25633099
Next-generation sequencing for the diagnosis of cardiac arrhythmia syndromes. PMID:25625719
Post-transcriptional regulation of long noncoding RNAs in cancer. PMID:25618601
Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio. PMID:25614875
Genome-wide analyses of LINE-LINE-mediated nonallelic homologous recombination. PMID:25613453
The expanding role of epigenetics. PMID:25610838
Methylation status of long interspersed element-1 in advanced gastric cancer and its prognostic implication. PMID:25609453
New concepts in breast cancer genomics and genetics. PMID:25606588
Repeated horizontal transfers of four DNA transposons in invertebrates and bats. PMID:25606061
Development of a monoclonal antibody specific to the endonuclease domain of the human LINE-1 ORF2 protein. PMID:25606060
Intragenomic distribution of RTE retroelements suggests intrachromosomal movement. PMID:25605325
A droplet digital PCR detection method for rare L1 insertions in tumors. PMID:25598847
Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area. PMID:25598768
The cytoplasmic tail of retroviral envelope glycoproteins. PMID:25595807
Relationship between nucleosome positioning and progesterone-induced alternative splicing in breast cancer cells. PMID:25589247
Computational cancer biology: education is a natural key to many locks. PMID:25588624
Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins. PMID:25575812
Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions. PMID:25572935
The expanding epigenetic landscape of non-model organisms. PMID:25568458
Diversity and impact of rare variants in genes encoding the platelet G protein-coupled receptors. PMID:25567036
Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities. PMID:25563503
Why and how might genetic and phylogenetic diversity be reflected in the identification of key biodiversity areas? PMID:25561678
Identification and computational analysis of gene regulatory elements. PMID:25561628
Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. PMID:25561044
Long non-coding RNAs as regulators of the endocrine system. PMID:25560704
RNA-binding proteins in pluripotency, differentiation, and reprogramming. PMID:25554730
Epigenetic effects of low perinatal doses of flame retardant BDE-47 on mitochondrial and nuclear genes in rat offspring. PMID:25533936
Biased gene conversion and GC-content evolution in the coding sequences of reptiles and vertebrates. PMID:25527834
Decelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes. PMID:25523484
Inhibition of autoimmune Chagas-like heart disease by bone marrow transplantation. PMID:25521296
DNA polymerases in biotechnology. PMID:25520711
Genome-wide analysis of alternative splicing in Volvox carteri. PMID:25516378
Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs. PMID:25504731
Comparative genomics reveals insights into avian genome evolution and adaptation. PMID:25504712
Multiple lineages of ancient CR1 retroposons shaped the early genome evolution of amniotes. PMID:25503085
Early mesozoic coexistence of amniotes and hepadnaviridae. PMID:25501991
Focusing on long noncoding RNA dysregulation in gastric cancer. PMID:25501508
Splicing of designer exons informs a biophysical model for exon definition. PMID:25492963
Gene expression profiling of replicative and induced senescence. PMID:25483067
Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression. PMID:25478632
JTD special edition 'Hot Topics in COPD'-The microbiome in COPD. PMID:25478194
Extensive error in the number of genes inferred from draft genome assemblies. PMID:25474019
Construction and characterization of three wheat bacterial artificial chromosome libraries. PMID:25464379
Genetics of allergic diseases. PMID:25459575
Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins. PMID:25436857
Genes regulating lipid and protein metabolism are highly expressed in mammary gland of lactating dairy goats. PMID:25433708
Guanine quadruplexes are formed by specific regions of human transposable elements. PMID:25431265
Using protein-binding microarrays to study transcription factor specificity: homologs, isoforms and complexes. PMID:25431149
A pathophysiological view of the long non-coding RNA world. PMID:25428918
Autoimmune thyroid disease and rheumatoid arthritis: relationship and the role of genetics. PMID:25427993
A case study in connectomics: the history, mapping, and connectivity of the claustrum. PMID:25426062
Advances in genome editing technology and its promising application in evolutionary and ecological studies. PMID:25414792
Host control of insect endogenous retroviruses: small RNA silencing and immune response. PMID:25412365
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. PMID:25411453
Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling. PMID:25411189
Roles of intragenic and intergenic L1s in mouse and human. PMID:25409429
Using mouse models to study function of transcriptional factors in T cell development. PMID:25408871
De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics. PMID:25405465
Identification of rare alternative splicing events in MS/MS data reveals a significant fraction of alternative translation initiation sites. PMID:25405079
Protein engineering of Cas9 for enhanced function. PMID:25398355
Intronic variants in the NFKB1 gene may influence hearing forecast in patients with unilateral sensorineural hearing loss in Meniere's disease. PMID:25397881
Clinical Management of Pediatric Genomic Testing. PMID:25396100
Gene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING Studies. PMID:25396097
Stress and the dynamic genome: Steroids, epigenetics, and the transposome. PMID:25385609
Resolving the complexity of the human genome using single-molecule sequencing. PMID:25383537
Identification of candidate long noncoding RNAs associated with left ventricular hypertrophy. PMID:25382655
Particles and microfluidics merged: perspectives of highly sensitive diagnostic detection. PMID:25378716
Epidaurus: aggregation and integration analysis of prostate cancer epigenome. PMID:25378314
DEEP: a general computational framework for predicting enhancers. PMID:25378307
Multispecies coalescent analysis of the early diversification of neotropical primates: phylogenetic inference under strong gene trees/species tree conflict. PMID:25377940
Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate. PMID:25377354
A comparative study and a phylogenetic exploration of the compositional architectures of mammalian nuclear genomes. PMID:25375262
A novel Alu-based real-time PCR method for the quantitative detection of plasma circulating cell-free DNA: sensitivity and specificity for the diagnosis of myocardial infarction. PMID:25374065
Case-only exome sequencing and complex disease susceptibility gene discovery: study design considerations. PMID:25371537
Three-Dimensional Algebraic Models of the tRNA Code and 12 Graphs for Representing the Amino Acids. PMID:25370377
Reconceptualizing major depressive disorder as an infectious disease. PMID:25364500
AN EFFICIENT ALGORITHM FOR CHINESE POSTMAN WALK ON BI-DIRECTED DE BRUIJN GRAPHS. PMID:25364472
Human cardiac systems electrophysiology and arrhythmogenesis: iteration of experiment and computation. PMID:25362174
Diverse and widespread contamination evident in the unmapped depths of high throughput sequencing data. PMID:25354084
Investigating genomic structure using changept: A Bayesian segmentation model. PMID:25349679
Mobster: accurate detection of mobile element insertions in next generation sequencing data. PMID:25348035
Control of mammalian retrotransposons by cellular RNA processing activities. PMID:25346866
iDoComp: a compression scheme for assembled genomes. PMID:25344501
Ovarian cancer biomarker discovery based on genomic approaches. PMID:25337559
The evolution of comparative genomics. PMID:25333060
A pilot study of angiotensin converting enzyme (ACE) genotype and return of spontaneous circulation following out-of-hospital cardiac arrest. PMID:25332829
Hydrophobicity and aromaticity are primary factors shaping variation in amino acid usage of chicken proteome. PMID:25329059
In vitro, long-range sequence information for de novo genome assembly via transposase contiguity. PMID:25327137
Widespread contribution of transposable elements to the innovation of gene regulatory networks. PMID:25319995
The impact of transposable elements in genome evolution and genetic instability and their implications in various diseases. PMID:25317108
Deep sequencing reveals low incidence of endogenous LINE-1 retrotransposition in human induced pluripotent stem cells. PMID:25289675
An evaluation of regulatory and commercial barriers to stratified medicine development and adoption. PMID:25287070
Multiple Mechanisms Contribute To Telomere Maintenance. PMID:25285314
Genetic networks governing heart development. PMID:25280899
Retrotransposon-based profiling of mammalian epigenomes: DNA methylation of IAP LTRs in embryonic stem, somatic and cancer cells. PMID:25277721
LINE-1 hypomethylation in blood and tissue samples as an epigenetic marker for cancer risk: a systematic review and meta-analysis. PMID:25275447
Promoter analysis reveals globally differential regulation of human long non-coding RNA and protein-coding genes. PMID:25275320
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons. PMID:25274305
Proliferation of endogenous retroviruses in the early stages of a host germ line invasion. PMID:25261407
Hybrid and rogue kinases encoded in the genomes of model eukaryotes. PMID:25255313
Managing, analysing, and integrating big data in medical bioinformatics: open problems and future perspectives. PMID:25254202
Comprehensive analysis of mutually exclusive alternative splicing in C. elegans. PMID:25254147
ARYANA: Aligning Reads by Yet Another Approach. PMID:25252881
A comprehensive transcriptomic analysis of infant and adult mouse ovary. PMID:25251848
Analysis of the role of homology arms in gene-targeting vectors in human cells. PMID:25250686
Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression. PMID:25249627
SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. PMID:25247314
Human endogenous retroviral elements promote genome instability via non-allelic homologous recombination. PMID:25246103
The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation. PMID:25245017
Allelic mapping bias in RNA-sequencing is not a major confounder in eQTL studies. PMID:25239376
Function and dynamics of macromolecular complexes explored by integrative structural and computational biology. PMID:25238653
Molecular characterization of common fragile sites as a strategy to discover cancer susceptibility genes. PMID:25231336
Rolling-circle transposons catalyze genomic innovation in a mammalian lineage. PMID:25223768
Random forest-based protein model quality assessment (RFMQA) using structural features and potential energy terms. PMID:25222008
Human serotonin receptor 5-HT(1A) preferentially segregates to the liquid disordered phase in synthetic lipid bilayers. PMID:25211019
Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency. PMID:25211013
We are all individuals... bioinformatics in the personalized medicine era. PMID:25204962
Direct binding of the Alu binding protein dimer SRP9/14 to 40S ribosomal subunits promotes stress granule formation and is regulated by Alu RNA. PMID:25200073
The evolution of tyrosine-recombinase elements in Nematoda. PMID:25197791
Evidence for the persistence of an active endogenous retrovirus (ERVE) in humans. PMID:25192754
Two low coverage bird genomes and a comparison of reference-guided versus de novo genome assemblies. PMID:25192061
Illumina TruSeq synthetic long-reads empower de novo assembly and resolve complex, highly-repetitive transposable elements. PMID:25188499
Recruitment of Yoruba families from Nigeria for genetic research: experience from a multisite keloid study. PMID:25182071
Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain. PMID:25180573
Open access data sharing in genomic research. PMID:25178093
Microsatellite-centromere mapping in common carp through half-tetrad analysis in diploid meiogynogenetic families. PMID:25171918
The architecture of a scrambled genome reveals massive levels of genomic rearrangement during development. PMID:25171416
Genomic Variation: Lessons Learned from Whole-Genome CNV Analysis. PMID:25152847
LINEs and SINEs of primate evolution. PMID:25147443
Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci. PMID:25143528
Relating gene expression evolution with CpG content changes. PMID:25142157
The lncRNA-MYC regulatory network in cancer. PMID:25139102
Epidemiological studies of esophageal cancer in the era of genome-wide association studies. PMID:25133033
Current status of predictive biomarkers for neoadjuvant therapy in esophageal cancer. PMID:25133032
Environmental alterations of epigenetics prior to the birth. PMID:25131541
Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing. PMID:25129063
Decreased LINE-1 methylation levels in aldosterone-producing adenoma. PMID:25120789
Transcriptome analysis of red swamp crawfish Procambarus clarkii reveals genes involved in gonadal development. PMID:25118947
A comprehensive reference transcriptome resource for the common house spider Parasteatoda tepidariorum. PMID:25118601
A long non-coding RNA is required for targeting centromeric protein A to the human centromere. PMID:25117489
Distinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma. PMID:25114248
In silico modeling of human α2C-adrenoreceptor interaction with filamin-2. PMID:25110951
TGF- β: an important mediator of allergic disease and a molecule with dual activity in cancer development. PMID:25110717
Current technologies to identify protein kinase substrates in high throughput. PMID:25110472
Discovery of modulators of HIV-1 infection from the human peptidome. PMID:25110191
LINE-1 retrotransposons: from 'parasite' sequences to functional elements. PMID:25106509
Environmental bacteriophages: viruses of microbes in aquatic ecosystems. PMID:25104950
Histidine kinases mediate differentiation, stress response, and pathogenicity in Magnaporthe oryzae. PMID:25103193
Drafts of the human proteome. PMID:25101745
The structure and retrotransposition mechanism of LTR-retrotransposons in the asexual yeast Candida albicans. PMID:25101670
Validation of high throughput sequencing and microbial forensics applications. PMID:25101166
Generation of physical map contig-specific sequences. PMID:25101119
Improved sensitivity to detect recombination using qPCR for Dyskeratosis Congenita PGD. PMID:25099625
Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential. PMID:25097266
A high resolution map of mammalian X chromosome fragile regions assessed by large-scale comparative genomics. PMID:25086724
LIA4 encodes a chromoshadow domain protein required for genomewide DNA rearrangements in Tetrahymena thermophila. PMID:25084866
Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. PMID:25082706
The DNA methylation landscape of human early embryos. PMID:25079557
Mammalian piRNAs: Biogenesis, function, and mysteries. PMID:25077039
The quality of methods reporting in parasitology experiments. PMID:25076044
Periodontal microbiology--the lid's off the box again. PMID:25074493
Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease - How Anti-Diabetics Could be a Solution for Dementia. PMID:25071725
The dynamic exome: acquired variants as individuals age. PMID:25063753
Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes. PMID:25063042
Expression and detection of LINE-1 ORF-encoded proteins. PMID:25054082
Survey on knowledge, attitudes, and training needs of Italian residents on genetic tests for hereditary breast and colorectal cancer. PMID:25050348
Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signalling. PMID:25048571
Genomic data integration for ecological and evolutionary traits in non-model organisms. PMID:25047861
Functional repeat-derived RNAs often originate from retrotransposon-propagated ncRNAs. PMID:25045147
Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention. PMID:25044704
Noncoding RNAs and the borders of heterochromatin. PMID:25044367
De novo LINE-1 retrotransposition in HepG2 cells preferentially targets gene poor regions of chromosome 13. PMID:25043885
Unraveling recombination rate evolution using ancestral recombination maps. PMID:25043668
Parallel universes of Black Six biology. PMID:25038798
The common marmoset genome provides insight into primate biology and evolution. PMID:25038751
Larger mammalian body size leads to lower retroviral activity. PMID:25033295
Effective automated feature construction and selection for classification of biological sequences. PMID:25033270
Microsatellite interruptions stabilize primate genomes and exist as population-specific single nucleotide polymorphisms within individual human genomes. PMID:25033203
Data integration in the era of omics: current and future challenges. PMID:25032990
G-protein βγ subunit dimers modulate kidney repair after ischemia-reperfusion injury in rats. PMID:25028481
Novel diet-related mouse model of colon cancer parallels human colon cancer. PMID:25024814
Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells. PMID:25024383
Mammalian-wide interspersed repeat (MIR)-derived enhancers and the regulation of human gene expression. PMID:25018785
Conventional and genetic talent identification in sports: will recent developments trace talent? PMID:25015477
Transcriptional landscape of repetitive elements in normal and cancer human cells. PMID:25012247
Fine mapping and functional studies of risk variants for type 1 diabetes at chromosome 16p13.13. PMID:25008175
Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer. PMID:25006803
Mobile DNA elements in the generation of diversity and complexity in the brain. PMID:25005482
High-throughput targeted repeat element bisulfite sequencing (HT-TREBS): genome-wide DNA methylation analysis of IAP LTR retrotransposon. PMID:25003790
Expanding the computational toolbox for mining cancer genomes. PMID:25001846
A cross-sectional study of global DNA methylation and risk of colorectal adenoma. PMID:24998982
Exome sequencing from nanogram amounts of starting DNA: comparing three approaches. PMID:24992588
Bioinformatics education--perspectives and challenges out of Africa. PMID:24990350
Searching for repeats, as an example of using the generalised Ruzzo-Tompa algorithm to find optimal subsequences with gaps. PMID:24989859
Coherent somatic mutation in autoimmune disease. PMID:24988487
Human endogenous retrovirus-K(II) envelope induction protects neurons during HIV/AIDS. PMID:24988390
Chimpanzee-specific endogenous retrovirus generates genomic variations in the chimpanzee genome. PMID:24987855
eMERGEing progress in genomics-the first seven years. PMID:24987407
Similarities and differences between exome sequences found in a variety of tissues from the same individual. PMID:24984015
Tandem repeats and G-rich sequences are enriched at human CNV breakpoints. PMID:24983241
Systems biology in the context of big data and networks. PMID:24982882
Prenatal exposure to mixtures of xenoestrogens and repetitive element DNA methylation changes in human placenta. PMID:24980756
DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. PMID:24976726
Insertional hypermutation in mineral oil-induced plasmacytomas. PMID:24975032
Whole-genome sequence variation, population structure and demographic history of the Dutch population. PMID:24974849
Population distribution analyses reveal a hierarchy of molecular players underlying parallel endocytic pathways. PMID:24971745
Alu and LINE-1 hypomethylation is associated with HER2 enriched subtype of breast cancer. PMID:24971511
Panning for Long Noncoding RNAs. PMID:24970166
Comparative studies of vertebrate Beta integrin genes and proteins: ancient genes in vertebrate evolution. PMID:24970121
Reviving the dead: history and reactivation of an extinct l1. PMID:24968166
A de novo genome assembly algorithm for repeats and nonrepeats. PMID:24967398
Spy: a new group of eukaryotic DNA transposons without target site duplications. PMID:24966181
The evolution of the coding exome of the Arabidopsis species--the influences of DNA methylation, relative exon position, and exon length. PMID:24965500
Returning individual research results for genome sequences of pancreatic cancer. PMID:24963353
Epigenetic heredity of human height. PMID:24963031
BLAT-based comparative analysis for transposable elements: BLATCAT. PMID:24959585
The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function. PMID:24957874
Mobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogen. PMID:24956175
Ancestral repeats have shaped epigenome and genome composition for millions of years in Arabidopsis thaliana. PMID:24954583
Applications of RNA interference high-throughput screening technology in cancer biology and virology. PMID:24952721
Biochemical and bioinformatic methods for elucidating the role of RNA-protein interactions in posttranscriptional regulation. PMID:24951655
Epigenetic regulation of persistent pain. PMID:24948399
Nicotine and oxidative stress induced exomic variations are concordant and overrepresented in cancer-associated genes. PMID:24947164
The strength of the strongest ties in collaborative problem solving. PMID:24946798
Digital genotyping of macrosatellites and multicopy genes reveals novel biological functions associated with copy number variation of large tandem repeats. PMID:24945355
PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator. PMID:24939934
Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes. PMID:24939910
Obstacles and opportunities for the future of genomic medicine. PMID:24936509
Overexpression of piRNA pathway genes in epithelial ovarian cancer. PMID:24932571
Sequencing your genome: what does it mean? PMID:24932355
No effect of weight loss on LINE-1 methylation levels in peripheral blood leukocytes from postmenopausal overweight women. PMID:24930817
Effective suppression of dengue virus using a novel group-I intron that induces apoptotic cell death upon infection through conditional expression of the Bax C-terminal domain. PMID:24927852
Whole genome wide expression profiles on germination of Verticillium dahliae microsclerotia. PMID:24927478
LINE-1 hypomethylation is associated with the risk of coronary heart disease in Chinese population. PMID:24918913
Identification of candidate long non-coding RNAs in response to myocardial infarction. PMID:24917243
Structured RNAs and synteny regions in the pig genome. PMID:24917120
Discovering functional DNA elements using population genomic information: a proof of concept using human mtDNA. PMID:24916662
Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night. PMID:24914052
The mechanistic role of DNA methylation in myeloid leukemogenesis. PMID:24913729
Transposable elements in cancer as a by-product of stress-induced evolvability. PMID:24910642
Last-gen nostalgia: a lighthearted rant and reflection on genome sequencing culture. PMID:24904646
Using semantic web technologies to annotate and align microarray designs. PMID:24904201
A bioinformatic and computational study of myosin phosphatase subunit diversity. PMID:24898838
Genome at juncture of early human migration: a systematic analysis of two whole genomes and thirteen exomes from Kuwaiti population subgroup of inferred Saudi Arabian tribe ancestry. PMID:24896259
Exome sequencing: new insights into lipoprotein disorders. PMID:24893940
Protein-protein interactions and genetic diseases: The interactome. PMID:24892209
Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice? PMID:24890612
Simple sequence repeats in the national longitudinal study of adolescent health: an ethnically diverse resource for genetic analysis of health and behavior. PMID:24890516
Origin of spliceosomal introns and alternative splicing. PMID:24890509
Interpreting human genetic variation with in vivo zebrafish assays. PMID:24887202
Improvement of domain-level ortholog clustering by optimizing domain-specific sum-of-pairs score. PMID:24885064
Casposons: a new superfamily of self-synthesizing DNA transposons at the origin of prokaryotic CRISPR-Cas immunity. PMID:24884953
XSAnno: a framework for building ortholog models in cross-species transcriptome comparisons. PMID:24884593
Population genetic analysis of bi-allelic structural variants from low-coverage sequence data with an expectation-maximization algorithm. PMID:24884587
Physiology of the read-write genome. PMID:24882816
Heterochromatin controls γH2A localization in Neurospora crassa. PMID:24879124
Prediction of bacterial microRNAs and possible targets in human cell transcriptome. PMID:24871974
Human genetic variation and Parkinson's disease. PMID:24868370
microRNAs and Alu elements in the p53-Mdm2-Mdm4 regulatory network. PMID:24868102
Pharmacogenomics: Current State-of-the-Art. PMID:24865298
Elevated HERV-K mRNA expression in PBMC is associated with a prostate cancer diagnosis particularly in older men and smokers. PMID:24858205
HeteroGenome: database of genome periodicity. PMID:24857969
An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval. PMID:24857694
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment. PMID:24857660
The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs. PMID:24850885
Rapid evolution of piRNA pathway in the teleost fish: implication for an adaptation to transposon diversity. PMID:24846630
APOBEC3A deaminates transiently exposed single-strand DNA during LINE-1 retrotransposition. PMID:24843014
Repetitive genomic elements and overall DNA methylation changes in acute myeloid and childhood B-cell lymphoblastic leukemia patients. PMID:24841671
The birth and development of the DNA theory of inheritance: sixty years since the discovery of the structure of DNA. PMID:24840850
Blood from 'junk': the LTR chimeric transcript Pu.2 promotes erythropoiesis. PMID:24839466
CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity. PMID:24837675
Understanding the Dynamics of Gene Regulatory Systems; Characterisation and Clinical Relevance of cis-Regulatory Polymorphisms. PMID:24832652
Genotyping-by-Sequencing in Plants. PMID:24832503
Analysis of horse genomes provides insight into the diversification and adaptive evolution of karyotype. PMID:24828444
Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing. PMID:24823667
Global and local competition between exogenously introduced microRNAs and endogenously expressed microRNAs. PMID:24823356
Identification of Horizontally-transferred Genomic Islands and Genome Segmentation Points by Using the GC Profile Method. PMID:24822029
A Brief Review: The Z-curve Theory and its Application in Genome Analysis. PMID:24822026
Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors. PMID:24821386
Genomic landscape of human, bat, and ex vivo DNA transposon integrations. PMID:24809961
Evaluation of novel design strategies for developing zinc finger nucleases tools for treating human diseases. PMID:24808958
Development of rapidly evolving intron markers to estimate multilocus species trees of rodents. PMID:24804779
Realistic artificial DNA sequences as negative controls for computational genomics. PMID:24803667
Integrating omics technologies to study pulmonary physiology and pathology at the systems level. PMID:24802001
Variants of a Thermus aquaticus DNA polymerase with increased selectivity for applications in allele- and methylation-specific amplification. PMID:24800860
From Phenotype to Genotype: Enter Genomics and Transformation of Primary Health Care around the World. PMID:24799423
Molecular tumor board: the University of California-San Diego Moores Cancer Center experience. PMID:24797821
Epigenetic control of mobile DNA as an interface between experience and genome change. PMID:24795749
Integrating genomic, transcriptomic, and interactome data to improve Peptide and protein identification in shotgun proteomics. PMID:24792918
Conserved modular domains team up to latch-open active protein kinase Cα. PMID:24790081
Long noncoding RNA: significance and potential in skin biology. PMID:24789873
To be or not to be: the regulation of mRNA fate as a survival strategy during mammalian hibernation. PMID:24789358
Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics. PMID:24785449
Developmental transcriptome analysis of human erythropoiesis. PMID:24781209
Genetic interactions affecting human gene expression identified by variance association mapping. PMID:24771767
Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability. PMID:24767258
The new world of RNAs. PMID:24764762
Using VAAST to Identify Disease-Associated Variants in Next-Generation Sequencing Data. PMID:24763993
Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors: an in vivo and in vitro study. PMID:24762809
Microfluidic bead suspension hopper. PMID:24761972
Key regulators control distinct transcriptional programmes in blood progenitor and mast cells. PMID:24760698
Protein-centric N-glycoproteomics analysis of membrane and plasma membrane proteins. PMID:24754784
Defining functional DNA elements in the human genome. PMID:24753594
A novel tRNA variable number tandem repeat at human chromosome 1q23.3 is implicated as a boundary element based on conservation of a CTCF motif in mouse. PMID:24753417
An expanding universe of the non-coding genome in cancer biology. PMID:24747961
The enemy within: endogenous retroelements and autoimmune disease. PMID:24747712
Towards a molecular systems model of coronary artery disease. PMID:24743898
Transcription-associated R-loop formation across the human FMR1 CGG-repeat region. PMID:24743386
Revitalizing personalized medicine: respecting biomolecular complexities beyond gene expression. PMID:24739991
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. PMID:24736841
Long-read sequencing of chicken transcripts and identification of new transcript isoforms. PMID:24736250
Species-specific alternative splicing leads to unique expression of sno-lncRNAs. PMID:24734784
Matrix and backstage: cellular substrates for viral vaccines. PMID:24732259
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing. PMID:24728327
A quick guide to genomics and bioinformatics training for clinical and public audiences. PMID:24722068
A short guide to long non-coding RNA gene nomenclature. PMID:24716852
Genetics of polycystic ovary syndrome. PMID:24715512
Chromatin Organization by Repetitive Elements (CORE): A Genomic Principle for the Higher-Order Structure of Chromosomes. PMID:24710208
A reverse transcriptase-dependent mechanism is essential for murine preimplantation development. PMID:24710196
Next generation DNA sequencing and the future of genomic medicine. PMID:24710010
Deep investigation of Arabidopsis thaliana junk DNA reveals a continuum between repetitive elements and genomic dark matter. PMID:24709859
Retrotransposition in tumors and brains. PMID:24708615
Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. PMID:24706889
Illuminating the Transcriptome through the Genome. PMID:24705295
Association claims in the sequencing era. PMID:24705293
Genetics of Charcot-Marie-Tooth (CMT) Disease within the Frame of the Human Genome Project Success. PMID:24705285
In Vivo RNAi-Based Screens: Studies in Model Organisms. PMID:24705267
High SINE RNA Expression Correlates with Post-Transcriptional Downregulation of BRCA1. PMID:24705161
Identifying and characterizing regulatory sequences in the human genome with chromatin accessibility assays. PMID:24705081
A model of evolution of development based on germline penetration of new "no-junk" DNA. PMID:24704981
Microsatellites with macro-influence in ewing sarcoma. PMID:24704979
Transposable elements: from DNA parasites to architects of metazoan evolution. PMID:24704977
Deep sequencing to identify the causes of viral encephalitis. PMID:24699691
Mapping the structure and dynamics of genomics-related MeSH terms complex networks. PMID:24699262
A LINE-1 insertion in DLX6 is responsible for cleft palate and mandibular abnormalities in a canine model of Pierre Robin sequence. PMID:24699068
A brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruits. PMID:24698025
Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia. PMID:24695712
Transcriptional regulation of YWHAZ, the gene encoding 14-3-3ζ. PMID:24690670
Implications of human genome structural heterogeneity: functionally related genes tend to reside in organizationally similar genomic regions. PMID:24684786
Construction of a high-coverage bacterial artificial chromosome library and comprehensive genetic linkage map of yellowtail Seriola quinqueradiata. PMID:24684753
Correcting for differential transcript coverage reveals a strong relationship between alternative splicing and organism complexity. PMID:24682283
Genetic counselors' views and experiences with the clinical integration of genome sequencing. PMID:24671342
Personalized ophthalmology. PMID:24665880
Association studies of sporadic Parkinson's disease in the genomic era. PMID:24653658
A first generation BAC-based physical map of the half-smooth tongue sole (Cynoglossus semilaevis) genome. PMID:24650389
An efficient method for high-fidelity messenger RNA amplification from a small amount of total RNA. PMID:24648903
HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes. PMID:24648457
Technology: The $1,000 genome. PMID:24646979
Intellectual property rights and innovation: Evidence from the human genome. PMID:24639594
Quantitative theory of entropic forces acting on constrained nucleotide sequences applied to viruses. PMID:24639520
Nuclear function of Alus. PMID:24637839
RepARK--de novo creation of repeat libraries from whole-genome NGS reads. PMID:24634442
Missing links in cardiology: long non-coding RNAs enter the arena. PMID:24619481
Genome-wide signals of positive selection in human evolution. PMID:24619126
Billions of basepairs of recently expanded, repetitive sequences are eliminated from the somatic genome during copepod development. PMID:24618421
Multiple conserved regulatory domains promote Fezf2 expression in the developing cerebral cortex. PMID:24618363
Accommodating the load: The transposable element content of very large genomes. PMID:24616835
Diversity through duplication: whole-genome sequencing reveals novel gene retrocopies in the human population. PMID:24615986
Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry. PMID:24608367
Scanning of transposable elements and analyzing expression of transposase genes of sweet potato [Ipomoea batatas]. PMID:24608103
2013 Curt Stern Award Address. PMID:24607386
The challenges and importance of structural variation detection in livestock. PMID:24600474
DNA methylome in spleen of avian pathogenic Escherichia coli-challenged broilers and integration with mRNA expression. PMID:24599154
Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases. PMID:24598577
Human genetics' 50th anniversary issue. PMID:24595704
Transcriptome sequencing and De Novo analysis of Youngia japonica using the illumina platform. PMID:24595283
Data simulation in machine olfaction with the R package chemosensors. PMID:24586410
Stable C0T-1 repeat RNA is abundant and is associated with euchromatic interphase chromosomes. PMID:24581492
Deletion of Gpr128 results in weight loss and increased intestinal contraction frequency. PMID:24574718
Constraint and opportunity in genome innovation. PMID:24572460
Global patterns of apparent copy number variation in birds revealed by cross-species comparative genomic hybridization. PMID:24570127
Morphine induces redox-based changes in global DNA methylation and retrotransposon transcription by inhibition of excitatory amino acid transporter type 3-mediated cysteine uptake. PMID:24569088
Epigenetics in the pathogenesis of rheumatoid arthritis. PMID:24568138
Epigenetic modification, dehydration, and molecular crowding effects on the thermodynamics of i-motif structure formation from C-rich DNA. PMID:24564458
The synthetic biology future. PMID:24561910
Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer. PMID:24553397
Variation, evolution, and correlation analysis of C+G content and genome or chromosome size in different kingdoms and phyla. PMID:24551092
GATA5 CpG island hypermethylation is an independent predictor for poor clinical outcome in renal cell carcinoma. PMID:24549248
Sequencing, assembling, and correcting draft genomes using recombinant populations. PMID:24531727
An Introduction to Functional Genomics and Systems Biology. PMID:24527360
Point-of-care technologies for molecular diagnostics using a drop of blood. PMID:24525172
Genome-guided transcriptome assembly in the age of next-generation sequencing. PMID:24524156
Prediction and classification of ncRNAs using structural information. PMID:24521294
Comparative RNAi screens in C. elegans and C. briggsae reveal the impact of developmental system drift on gene function. PMID:24516395
Endogenous retroviruses and the development of cancer. PMID:24511094
Divergent and dynamic activity of endogenous retroviruses in burn patients and their inflammatory potential. PMID:24509167
Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function. PMID:24502763
A simple method for gene phasing using mate pair sequencing. PMID:24502676
Small-molecule probes elucidate global enzyme activity in a proteomic context. PMID:24499666
A new genome-wide method to track horizontally transferred sequences: application to Drosophila. PMID:24497602
Twenty-first century science as a relational process: from eureka! to team science and a place for community psychology. PMID:24496718
An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition. PMID:24493738
Comparing DNA integration site clusters with scan statistics. PMID:24489369
Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle. PMID:24487278
Nuclear architecture as an epigenetic regulator of neural development and function. PMID:24486963
Finding the missing honey bee genes: lessons learned from a genome upgrade. PMID:24479613
A new biophysical metric for interrogating the information content in human genome sequence variation: Proof of concept. PMID:24478921
Genome-scale analysis of demographic history and adaptive selection. PMID:24474201
Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection. PMID:24472118
Significant overlap between human genome-wide association-study nominated breast cancer risk alleles and rat mammary cancer susceptibility loci. PMID:24467842
Long non-coding RNA H19 promotes glioma cell invasion by deriving miR-675. PMID:24466011
Neurofilament Heavy polypeptide CpG island methylation associates with prognosis of renal cell carcinoma and prediction of antivascular endothelial growth factor therapy response. PMID:24464810
Alu- and 7SL RNA Analogues Suppress MCF-7 Cell Viability through Modulating the Transcription of Endoplasmic Reticulum Stress Response Genes. PMID:24455187
Diversity of human tRNA genes from the 1000-genomes project. PMID:24448271
An empirically informed critique of Habermas' argument from human nature. PMID:24446150
Bidirectional promoters are the major source of gene activation-associated non-coding RNAs in mammals. PMID:24438357
Effects of short-term exposure to inhalable particulate matter on DNA methylation of tandem repeats. PMID:24436168
The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research. PMID:24435092
Sequencing depth and coverage: key considerations in genomic analyses. PMID:24434847
The first draft of the pigeonpea genome sequence. PMID:24431589
Whole genome sequence of a Turkish individual. PMID:24416366
Toward an accurate prediction of inter-residue distances in proteins using 2D recursive neural networks. PMID:24410833
Post-genomics nanotechnology is gaining momentum: nanoproteomics and applications in life sciences. PMID:24410486
Horizontal gene transfer in the acquisition of novel traits by metazoans. PMID:24403327
A computational framework to infer human disease-associated long noncoding RNAs. PMID:24392133
An absolute index (Ab-index) to measure a researcher's useful contributions and productivity. PMID:24391941
Community-Based Participatory Research and Gene-Environment Interaction Methodologies Addressing Environmental Justice among Migrant and Seasonal Farmworker Women and Children in Texas: "From Mother to Child Project". PMID:24391476
Identification and characterisation of non-coding small RNAs in the pathogenic filamentous fungus Trichophyton rubrum. PMID:24377353
DIAMUND: direct comparison of genomes to detect mutations. PMID:24375697
Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin. PMID:24373511
Mutation discovery for Mendelian traits in non-laboratory animals: a review of achievements up to 2012. PMID:24372556
RNase L restricts the mobility of engineered retrotransposons in cultured human cells. PMID:24371271
APOBEC3G oligomerization is associated with the inhibition of both Alu and LINE-1 retrotransposition. PMID:24367644
(13)C NMR spectroscopy applications to brain energy metabolism. PMID:24367329
Zinc and the aging brain. PMID:24366781
Increased seroreactivity to HERV-K10 peptides in patients with HTLV myelopathy. PMID:24365054
Life cycle of an n-globin pseudogene microsatellite locus. PMID:24363661
A novel null homozygous mutation confirms CACNA2D2 as a gene mutated in epileptic encephalopathy. PMID:24358150
Next generation 1536-well oligonucleotide synthesizer with on-the-fly dispense. PMID:24355807
A novel recombinant retrovirus in the genomes of modern birds combines features of avian and mammalian retroviruses. PMID:24352464
Identification and biochemical characterization of protein phosphatase 5 from the cantharidin-producing blister beetle, Epicauta chinensis. PMID:24351830
CrossMap: a versatile tool for coordinate conversion between genome assemblies. PMID:24351709
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes. PMID:24347612
A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines. PMID:24345856
Differential inhibition of LINE1 and LINE2 retrotransposition by vertebrate AID/APOBEC proteins. PMID:24344916
De novo assembly of a field isolate genome reveals novel Plasmodium vivax erythrocyte invasion genes. PMID:24340114
Comparative genomic analysis of eutherian ribonuclease A genes. PMID:24337645
The population history of endogenous retroviruses in mule deer (Odocoileus hemionus). PMID:24336966
An age-of-allele test of neutrality for transposable element insertions. PMID:24336751
Concepts of tissue injury and cell death in inflammation: a historical perspective. PMID:24336099
Genome sequencing: a systematic review of health economic evidence. PMID:24330507
Characterization of L1 ORF1p self-interaction and cellular localization using a mammalian two-hybrid system. PMID:24324740
Students' perspective on genomics: from sample to sequence using the case study of blueberry. PMID:24324481
DNA transposon-based gene vehicles - scenes from an evolutionary drive. PMID:24320156
The roles of genetic polymorphisms and human immunodeficiency virus infection in lipid metabolism. PMID:24319689
Structural features and mechanism of translocation of non-LTR retrotransposons in Candida albicans. PMID:24317340
The Vertebrate Genome Annotation browser 10 years on. PMID:24316575
Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment. PMID:24314227
Enhancing systems medicine beyond genotype data by dynamic patient signatures: having information and using it too. PMID:24312119
MAKER-P: a tool kit for the rapid creation, management, and quality control of plant genome annotations. PMID:24306534
Genetic and epigenetic determinants mediate proneness of oncogene breakpoint sites for involvement in TCR translocations. PMID:24304972
Detection limit of intragenic deletions with targeted array comparative genomic hybridization. PMID:24304607
Influence of age, sex and genetic factors on the human brain. PMID:24297733
Comparative genomics of oral isolates of Streptococcus mutans by in silico genome subtraction does not reveal accessory DNA associated with severe early childhood caries. PMID:24291226
Rapid and inexpensive screening of genomic copy number variations using a novel quantitative fluorescent PCR method. PMID:24288428
L1 retrotransposons, cancer stem cells and oncogenesis. PMID:24286172
Molecular versatility: the many faces and functions of noncoding RNA. PMID:24281974
Not so pseudo anymore: pseudogenes as therapeutic targets. PMID:24279857
Alu mobile elements: from junk DNA to genomic gems. PMID:24278713
Genome-scale technology driven advances to research into normal and malignant haematopoiesis. PMID:24278696
Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains. PMID:24278487
DNA sequences at a glance. PMID:24278218
DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis. PMID:24278031
Stable RNA nanoparticles as potential new generation drugs for cancer therapy. PMID:24270010
Systematic classification of non-coding RNAs by epigenomic similarity. PMID:24267974
Role of pathogens in multiple sclerosis. PMID:24266364
Associations between serum perfluoroalkyl acids and LINE-1 DNA methylation. PMID:24263140
Microbial diversity in the era of omic technologies. PMID:24260747
Small RNAs, big impact: small RNA pathways in transposon control and their effect on the host stress response. PMID:24254230
InvFEST, a database integrating information of polymorphic inversions in the human genome. PMID:24253300
LINE-1 activation and epigenetic silencing of suppressor genes in cancer: Causally related events? PMID:24251074
Domesticated transposable element gene products in human cancer. PMID:24251072
Association and differentiation of MHC class I and II polymorphic Alu insertions and HLA-A, -B, -C and -DRB1 alleles in the Chinese Han population. PMID:24248811
Functional clustering of immunoglobulin superfamily proteins with protein-protein interaction information calibrated hidden Markov model sequence profiles. PMID:24246499
Identification of significant features in DNA microarray data. PMID:24244802
Linear decay of retrotransposon antisense bias across genes is contingent upon tissue specificity. PMID:24244495
Retrotransposon silencing during embryogenesis: dicer cuts in LINE. PMID:24244199
A sequence-ready physical map of barley anchored genetically by two million single-nucleotide polymorphisms. PMID:24243933
Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins. PMID:24241348
Human heart failure: is cell therapy a valid option? PMID:24239645
Functional microRNAs and target sites are created by lineage-specific transposition. PMID:24234653
Epigenetic regulation by long noncoding RNAs in plants. PMID:24233054
Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression. PMID:24231191
STaRRRT: a table of short tandem repeats in regulatory regions of the human genome. PMID:24228761
Metabolic mechanisms of epigenetic regulation. PMID:24228614
Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer. PMID:24220694
Identification of three new Alu Yb subfamilies by source tracking of recently integrated Alu Yb elements. PMID:24216009
Discovery of recurrent structural variants in nasopharyngeal carcinoma. PMID:24214394
Epigenomic elements enriched in the promoters of autoimmunity susceptibility genes. PMID:24213554
The nature of nurture: refining the definition of the exposome. PMID:24213143
Cancer genome sequencing and its implications for personalized cancer vaccines. PMID:24213133
Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer. PMID:24212657
Plasma proteomics, the Human Proteome Project, and cancer-associated alternative splice variant proteins. PMID:24211518
Classification of α-helical membrane proteins using predicted helix architectures. PMID:24204844
Condensin II subunit dCAP-D3 restricts retrotransposon mobilization in Drosophila somatic cells. PMID:24204294
The role of transposable elements in health and diseases of the central nervous system. PMID:24198348
Exome sequencing: one small step for malignant hyperthermia, one giant step for our specialty--why exome sequencing matters to all of us, not just the experts. PMID:24195944
Non-LTR retrotransposons and microsatellites: Partners in genomic variation. PMID:24195012
A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion. PMID:24190946
Perspective: a systems approach to diabetes research. PMID:24187547
DNA methylation profiling in X;autosome translocations supports a role for L1 repeats in the spread of X chromosome inactivation. PMID:24186870
Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity. PMID:24179441
Complexity of the alternative splicing landscape in plants. PMID:24179125
A 129-kb deletion on chromosome 12 confers substantial protection against rheumatoid arthritis, implicating the gene SLC2A3. PMID:24178905
The genomics of schizophrenia: update and implications. PMID:24177465
Intronic deletions in the SLC34A3 gene: a cautionary tale for mutation analysis of hereditary hypophosphatemic rickets with hypercalciuria. PMID:24176905
Old world monkeys and new age science: the evolution of nonhuman primate systems virology. PMID:24174440
Improving genome assemblies and annotations for nonhuman primates. PMID:24174438
Genetic and molecular alterations in pancreatic cancer: implications for personalized medicine. PMID:24172537
Functional transcriptomics in the post-ENCODE era. PMID:24172201
Gene regulation by non-coding RNAs. PMID:24164576
An emerging place for lung cancer genomics in 2013. PMID:24163742
Mutagenesis and phenotyping resources in zebrafish for studying development and human disease. PMID:24162064
Intron retention in the alternatively spliced region of RON results from weak 3' splice site recognition. PMID:24155930
Differential L1 regulation in pluripotent stem cells of humans and apes. PMID:24153179
Potential Antibacterial Targets in Bacterial Central Metabolism. PMID:24151543
Clinical implications of the LINE-1 methylation levels in patients with gastrointestinal cancer. PMID:24150097
The challenges, advantages and future of phenome-wide association studies. PMID:24147732
A review of bacteria-animal lateral gene transfer may inform our understanding of diseases like cancer. PMID:24146634
Next-generation sequencing for mitochondrial disorders. PMID:24138576
Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. PMID:24136355
Human genome replication proceeds through four chromatin states. PMID:24130466
Lessons from postgenome-wide association studies: functional analysis of cancer predisposition loci. PMID:24127939
Structure and Expression Analyses of SVA Elements in Relation to Functional Genes. PMID:24124410
Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients. PMID:24114970
Strong heterogeneity in mutation rate causes misleading hallmarks of natural selection on indel mutations in the human genome. PMID:24113537
De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts. PMID:24106303
Cancer genomics identifies disrupted epigenetic genes. PMID:24104525
"Conferring authorship": biobank stakeholders' experiences with publication credit in collaborative research. PMID:24098803
A novel actin mRNA splice variant regulates ACTG1 expression. PMID:24098136
Exploring mechanisms of human disease through structurally resolved protein interactome networks. PMID:24096645
Transposable elements and their potential role in complex lung disorder. PMID:24093510
BLUEPRINT: mapping human blood cell epigenomes. PMID:24091925
LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells. PMID:24089548
Guanine holes are prominent targets for mutation in cancer and inherited disease. PMID:24086153
Alu elements: an intrinsic source of human genome instability. PMID:24080407
Utilization of transposable element mPing as a novel genetic tool for modification of the stress response in rice. PMID:24078785
Mapping human epigenomes. PMID:24074860
Mass fingerprinting of complex mixtures: protein inference from high-resolution peptide masses and predicted retention times. PMID:24074221
Transcriptome profile of the green odorous frog (Odorrana margaretae). PMID:24073255
Lineage-specific duplications of Muroidea Faim and Spag6 genes and atypical accelerated evolution of the parental Spag6 gene. PMID:24071998
Contamination of live attenuated vaccines with an infectious feline endogenous retrovirus (RD-114 virus). PMID:24068581
Punctuated emergences of genetic and phenotypic innovations in eumetazoan, bilaterian, euteleostome, and hominidae ancestors. PMID:24065732
Splicing and alternative splicing in rice and humans. PMID:24064058
Association of endogenous retroviruses and long terminal repeats with human disorders. PMID:24062987
The genetics of NAFLD. PMID:24061205
Information measure for long-range correlated sequences: the case of the 24 human chromosomes. PMID:24056670
DNA sequencing methods in human genetics and disease research. PMID:24049638
Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline. PMID:24045705
The Human Genome Project: big science transforms biology and medicine. PMID:24040834
In vitro screening for compounds that enhance human L1 mobilization. PMID:24040300
Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. PMID:24040035
Long non-coding RNAs and complex human diseases. PMID:24036441
Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1. PMID:24035396
LINEs of evidence: noncanonical DNA replication as an epigenetic determinant. PMID:24034780
Genotyping of human neutrophil antigens (HNA) from whole genome sequencing data. PMID:24028078
CFTR activity and mitochondrial function. PMID:24024153
Insights into the loblolly pine genome: characterization of BAC and fosmid sequences. PMID:24023741
The relationship between gene isoform multiplicity, number of exons and protein divergence. PMID:24023641
Massively parallel sequencing: the new frontier of hematologic genomics. PMID:24021669
From helix to hematology: introduction to a collection of reviews on the emerging role of next-generation sequencing in hematology. PMID:24016460
Predicting whole genome protein interaction networks from primary sequence data in model and non-model organisms using ENTS. PMID:24015873
Lizards and LINEs: selection and demography affect the fate of L1 retrotransposons in the genome of the green anole (Anolis carolinensis). PMID:24013105
Splice variants of zinc finger protein 695 mRNA associated to ovarian cancer. PMID:24007497
Microbes, metagenomes and marine mammals: enabling the next generation of scientist to enter the genomic era. PMID:24007365
Population genetics and molecular evolution of DNA sequences in transposable elements. I. A simulation framework. PMID:24002643
Effect of heavy metals on silencing of engineered long interspersed element-1 retrotransposon in nondividing neuroblastoma cell line. PMID:23999712
The MaSuRCA genome assembler. PMID:23990416
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PMID:23977022
Refrex-1, a soluble restriction factor against feline endogenous and exogenous retroviruses. PMID:23966402
Towards precision medicine: advances in computational approaches for the analysis of human variants. PMID:23962656
Segmenting the human genome based on states of neutral genetic divergence. PMID:23959903
Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore. PMID:23957506
Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemia. PMID:23941516
Prolonged treatment with DNMT inhibitors induces distinct effects in promoters and gene-bodies. PMID:23940695
Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase. PMID:23940045
Paleovirology of 'syncytins', retroviral env genes exapted for a role in placentation. PMID:23938756
Exploring the effects of immunity and life history on the dynamics of an endogenous retrovirus. PMID:23938754
'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era. PMID:23938753
Comprehensive analysis of endogenous bornavirus-like elements in eukaryote genomes. PMID:23938751
Visualized computational predictions of transcriptional effects by intronic endogenous retroviruses. PMID:23936536
Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR. PMID:23936419
Mitogenomes from two uncommon haplogroups mark late glacial/postglacial expansions from the near east and neolithic dispersals within Europe. PMID:23936216
The Profile of Human Sperm Proteome; A Mini-review. PMID:23926502
The nuage mediates retrotransposon silencing in mouse primordial ovarian follicles. PMID:23924633
Evaluation of genome sequencing quality in selected plant species using expressed sequence tags. PMID:23922843
Detecting Alu insertions from high-throughput sequencing data. PMID:23921633
Progress toward personalized medicine for glaucoma. PMID:23914252
Identification of cis-regulatory modules in promoters of human genes exploiting mutual positioning of transcription factors. PMID:23913413
The Future of Children's Health in the Genomic Era. PMID:23908811
The application of next-generation sequencing in the autozygosity mapping of human recessive diseases. PMID:23907654
Locating Pb2+ and Zn2+ in zinc finger-like peptides using mass spectrometry. PMID:23907592
Profiling the immune stromal interface in breast cancer and its potential for clinical impact. PMID:23904829
Organelle targeting: third level of drug targeting. PMID:23898223
Single-cell sequencing-based technologies will revolutionize whole-organism science. PMID:23897237
Epigenetic signature and enhancer activity of the human APOE gene. PMID:23892237
REViewer: a tool for linear visualization of repetitive elements within a sequence query. PMID:23891933
Detecting and comparing non-coding RNAs in the high-throughput era. PMID:23887659
Unraveling genomic variation from next generation sequencing data. PMID:23885890
Rates and patterns of great ape retrotransposition. PMID:23884656
Cigarette smoking and DNA methylation. PMID:23882278
Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes. PMID:23880067
Recurrent HERV-H-mediated 3q13.2-q13.31 deletions cause a syndrome of hypotonia and motor, language, and cognitive delays. PMID:23878096
Hypomethylation of long interspersed nuclear element-1 promoter is associated with poor outcomes for curative resected hepatocellular carcinoma. PMID:23875825
Translational genetics for diagnosis of human disorders of sex development. PMID:23875799
A superfamily of DNA transposons targeting multicopy small RNA genes. PMID:23874566
Lessons from next-generation sequencing analysis in hematological malignancies. PMID:23872706
Evolution: life has evolved to evolve: comment on "How life changes itself: the Read-Write (RW) genome" by James Shapiro. PMID:23871431
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species. PMID:23870653
Spatial localization of genes determined by intranuclear DNA fragmentation with the fusion proteins lamin KRED and histone KRED und visible light. PMID:23869190
Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion. PMID:23868074
Global DNA methylation in a population with aflatoxin B1 exposure. PMID:23867725
Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis. PMID:23866266
Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis. PMID:23864388
A versatile microsatellite instability reporter system in human cells. PMID:23861444
Dominant form of congenital hyperinsulinism maps to HK1 region on 10q. PMID:23859901
Evolutionary age of repetitive element subfamilies and sensitivity of DNA methylation to airborne pollutants. PMID:23855992
The sequence signature of an Ig-fold. PMID:23842991
Periodic distribution of a putative nucleosome positioning motif in human, nonhuman primates, and archaea: mutual information analysis. PMID:23841049
Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples. PMID:23840181
The Mighty Mouse: the impact of rodents on advances in biomedical research. PMID:23829104
STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown. PMID:23824540
CluGene: A Bioinformatics Framework for the Identification of Co-Localized, Co-Expressed and Co-Regulated Genes Aimed at the Investigation of Transcriptional Regulatory Networks from High-Throughput Expression Data. PMID:23823315
Homoeologous chromosomes of Xenopus laevis are highly conserved after whole-genome duplication. PMID:23820579
Controlled insertional mutagenesis using a LINE-1 (ORFeus) gene-trap mouse model. PMID:23818630
Understanding the regulatory and transcriptional complexity of the genome through structure. PMID:23817049
Comparative genomics as a tool to understand evolution and disease. PMID:23817047
Jenner-predict server: prediction of protein vaccine candidates (PVCs) in bacteria based on host-pathogen interactions. PMID:23815072
Copy number variation of transposable elements in Triticum-Aegilops genus suggests evolutionary and revolutionary dynamics following allopolyploidization. PMID:23807536
Genomic analysis of ERVWE2 locus in patients with multiple sclerosis: absence of genetic association but potential role of human endogenous retrovirus type W elements in molecular mimicry with myelin antigen. PMID:23805135
The intertwining of transposable elements and non-coding RNAs. PMID:23803660
Enhancers. PMID:23801531
RNA-seq in the tetraploid Xenopus laevis enables genome-wide insight in a classic developmental biology model organism. PMID:23792920
The impact of natural selection on health and disease: uses of the population genetics approach in humans. PMID:23789027
Epigenetic mechanisms in fetal origins of health and disease. PMID:23787712
Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation. PMID:23782695
GAT: a simulation framework for testing the association of genomic intervals. PMID:23782611
Evolution of the correlation between expression divergence and protein divergence in mammals. PMID:23781097
Special considerations in prognostic research in cancer involving genetic polymorphisms. PMID:23773794
Analysis of 8 X-chromosomal markers in the population of central Croatia. PMID:23771754
On guard: coronin proteins in innate and adaptive immunity. PMID:23765056
QualComp: a new lossy compressor for quality scores based on rate distortion theory. PMID:23758828
Passive and active DNA methylation and the interplay with genetic variation in gene regulation. PMID:23755361
A comparison of 100 human genes using an alu element-based instability model. PMID:23755193
Storage conditions and stability of global DNA methylation in placental tissue. PMID:23750648
The role of recombination in the origin and evolution of Alu subfamilies. PMID:23750218
Statistical analysis of pentose phosphate pathway genes from eubacteria and eukarya reveals translational selection as a major force in shaping codon usage pattern. PMID:23750079
Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition. PMID:23749060
Cancer epigenetics: a brief review. PMID:23744972
Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases. PMID:23743227
Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. PMID:23739767
Next-generation sequencing in genetic hearing loss. PMID:23738631
Transposable element invasions. PMID:23734297
Studying recombination with high-throughput sequencing: an educational primer for use with "fine-scale heterogeneity in crossover rate in the garnet-scalloped region of the Drosophila melanogaster X chromosome". PMID:23733850
Expansion of the pseudo-autosomal region and ongoing recombination suppression in the Silene latifolia sex chromosomes. PMID:23733786
Genomics and genetics in the biology of adaptation to exercise. PMID:23733655
LINE-1 and Alu retrotransposition exhibit clonal variation. PMID:23732044
Improved coverage and accuracy with strand-conserving sequence enrichment. PMID:23731654
Machine learning and genome annotation: a match meant to be? PMID:23731483
Enzymatic production of 'monoclonal stoichiometric' single-stranded DNA oligonucleotides. PMID:23727986
The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells. PMID:23727884
Survival analysis with incomplete genetic data. PMID:23722305
High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration. PMID:23720718
Genome-wide characterization of endogenous retroviruses in the bat Myotis lucifugus reveals recent and diverse infections. PMID:23720713
The role of retrotransposons in gene family expansions: insights from the mouse Abp gene family. PMID:23718880
Expression of a LINE-1 endonuclease variant in gastric cancer: its association with clinicopathological parameters. PMID:23718141
Alu elements in primates are preferentially lost from areas of high GC content. PMID:23717800
ZNF408 is mutated in familial exudative vitreoretinopathy and is crucial for the development of zebrafish retinal vasculature. PMID:23716654
Posttranscriptional regulation by RNA-binding proteins during epithelial-to-mesenchymal transition. PMID:23715860
REAPR: a universal tool for genome assembly evaluation. PMID:23710727
Emerging tools for synthetic genome design. PMID:23708771
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. PMID:23708189
Retroviruses and amyotrophic lateral sclerosis. PMID:23707220
HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition. PMID:23706308
PeSV-Fisher: identification of somatic and non-somatic structural variants using next generation sequencing data. PMID:23704902
Identification of a novel PNMA-MS1 gene in marsupials suggests the LTR retrotransposon-derived PNMA genes evolved differently in marsupials and eutherians. PMID:23704700
Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer. PMID:23703216
Assembling the 20 Gb white spruce (Picea glauca) genome from whole-genome shotgun sequencing data. PMID:23698863
Footprint of APOBEC3 on the genome of human retroelements. PMID:23698293
Comparative genomic and transcriptomic analysis of tandemly and segmentally duplicated genes in rice. PMID:23696832
Human monogenic disease genes have frequently functionally redundant paralogs. PMID:23696728
Enrichment of processed pseudogene transcripts in L1-ribonucleoprotein particles. PMID:23696454
Rapid multiplexed genotyping of simple tandem repeats using capture and high-throughput sequencing. PMID:23696428
On the classification of long non-coding RNAs. PMID:23696037
ABC transporters in multidrug resistance and pharmacokinetics, and strategies for drug development. PMID:23688078
Structural and functional annotation of the porcine immunome. PMID:23676093
A human anti-c-Met Fab fragment conjugated with doxorubicin as targeted chemotherapy for hepatocellular carcinoma. PMID:23675455
The specificity and flexibility of l1 reverse transcription priming at imperfect T-tracts. PMID:23675310
Genetic variation and its role in malignancy. PMID:23675233
Overlapping of genes in the human genome. PMID:23675016
Information theory, gene expression, and combinatorial regulation: a quantitative analysis. PMID:23674094
GATA simple sequence repeats function as enhancer blocker boundaries. PMID:23673629
Molecular evolution of peptidergic signaling systems in bilaterians. PMID:23671109
eQTL Mapping Using RNA-seq Data. PMID:23667399
Retrotransposons: a new and credible source of inherited and somatically acquired hepatocellular carcinoma mutations. PMID:23665280
A gene expression restriction network mediated by sense and antisense Alu sequences located on protein-coding messenger RNAs. PMID:23663499
Multiple suboptimal solutions for prediction rules in gene expression data. PMID:23662163
Detection of serum Alu element hypomethylation for the diagnosis and prognosis of glioma. PMID:23657981
Multiple sclerosis: autoimmunity and viruses. PMID:23656710
Digital quantitation of potential therapeutic target RNAs. PMID:23656494
Sixty years of genome biology. PMID:23651518
DNA methylation: the future of crime scene investigation? PMID:23649761
Identification of multiple binding sites for the THAP domain of the Galileo transposase in the long terminal inverted-repeats. PMID:23648487
Reprogramming of the HepG2 genome by long interspersed nuclear element-1. PMID:23648019
Long noncoding RNAs in biology and hematopoiesis. PMID:23645840
Genomic dynamics of transposable elements in the western clawed frog (Silurana tropicalis). PMID:23645600
Genomic resources for multiple species in the Drosophila ananassae species group. PMID:23639891
Influence of the experimental design of gene expression studies on the inference of gene regulatory networks: environmental factors. PMID:23638344
Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs. PMID:23637635
Role of the human endogenous retrovirus HERV-K18 in autoimmune disease susceptibility: study in the Spanish population and meta-analysis. PMID:23634223
Discovery and mass spectrometric analysis of novel splice-junction peptides using RNA-Seq. PMID:23629695
Systematic biases in DNA copy number originate from isolation procedures. PMID:23618369
Genetics of coronary artery disease and myocardial infarction--2013. PMID:23616109
Genome-wide analysis of alternative splicing during dendritic cell response to a bacterial challenge. PMID:23613991
Sequence and structure-specific elements of HERG mRNA determine channel synthesis and trafficking efficiency. PMID:23608144
The challenge of increasing Pfam coverage of the human proteome. PMID:23603847
Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology. PMID:23603631
The human qualities needed to complete the global eradication of polio. PMID:23599552
Mobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations. PMID:23599355
Are results of targeted gene sequencing ready to be used for clinical decision making for patients with acute myelogenous leukemia? PMID:23595294
Computational solutions for omics data. PMID:23594911
Cancer genome-sequencing study design. PMID:23594910
Human-specific HERV-K insertion causes genomic variations in the human genome. PMID:23593260
Revising a personal genome by comparing and combining data from two different sequencing platforms. PMID:23593254
Identification of optimum sequencing depth especially for de novo genome assembly of small genomes using next generation sequencing data. PMID:23593174
Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing. PMID:23590730
Existing and emerging technologies for tumor genomic profiling. PMID:23589546
Mathematical modeling of complex biological systems: from parts lists to understanding systems behavior. PMID:23584751
IMACULAT - an open access package for the quantitative analysis of chromosome localization in the nucleus. PMID:23577217
The use of RelocaTE and unassembled short reads to produce high-resolution snapshots of transposable element generated diversity in rice. PMID:23576519
Searching microsatellites in DNA sequences: approaches used and tools developed.