FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

polymirts
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

Other names: PolymiRTS, polymirts

PolymiRTS (Polymorphism in microRNAs and their TargetSites) is a database of naturally occurring DNA variations in microRNA (miRNA) seed regions and miRNA target sites. MicroRNAs pair to the transcripts of protein-coding genes and cause translational repression or mRNA destabilization. SNPs and INDELs in miRNAs and their target sites may affect miRNA-mRNA interaction, and hence affect miRNA-mediated gene repression.

Webpage:

http://compbio.uthsc.edu/miRSNP/

Publications:

Publications
More detailed information about this field from each metasource.

PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways
PMID: 24163105
metasource: Fairsharing.org
version: FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits
PMID: 17099235
metasource: Fairsharing.org
version: FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits
PMID: 22080514
metasource: Fairsharing.org
version: FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

http://dx.doi.org/10.1093/nar/gkt1028
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways PubMed citations: 140.

140 articles citing: PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways

In silico comprehensive analysis of coding and non-coding SNPs in human mTOR protein. PMID:35788771
Association of a miRNA-binding site polymorphism in IL-16 gene with disease risk and clinical characteristics of rheumatoid arthritis and systemic lupus erythematosus. PMID:35332405
Comprehensive Characterization of the Coding and Non-Coding Single Nucleotide Polymorphisms in the Tumor Protein p63 (TP63) Gene Using In Silico Tools. PMID:34827731
A computational in silico approach to predict high-risk coding and non-coding SNPs of human PLCG1 gene. PMID:34793541
Association between ADCY9 Gene Polymorphisms and Ritodrine Treatment Outcomes in Patients with Preterm Labor. PMID:34683946
Molecular insights into the role of genetic determinants of congenital hypothyroidism. PMID:34638176
Nuclear Pore Glycoprotein 62 Genetic Variant rs9523 is Associated with Clinical Outcomes of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Lung Adenocarcinoma Patients. PMID:34629889
Emerging Role of isomiRs in Cancer: State of the Art and Recent Advances. PMID:34573429
Mapping the miRNA-mRNA Interactome in Human Hepatocytes and Identification of Functional mirSNPs in Pharmacogenes. PMID:34314509
Evaluating the Effect of 3'-UTR Variants in DICER1 and DROSHA on Their Tissue-Specific Expression by miRNA Target Prediction. PMID:34287278
Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry. PMID:34201152
Immune System and Neuroinflammation in Idiopathic Parkinson's Disease: Association Analysis of Genetic Variants and miRNAs Interactions. PMID:34149802
Genetic Determinants Highlight the Existence of Shared Etiopathogenetic Mechanisms Characterizing Age-Related Macular Degeneration and Neurodegenerative Disorders. PMID:34135841
Structure analysis of deleterious nsSNPs in human PALB2 protein for functional inference. PMID:34092963
Identification of missense MAB21L1 variants in microphthalmia and aniridia. PMID:33973683
ANGPTL3 gene variants in subjects with familial combined hyperlipidemia. PMID:33772079
MicroRNA Expression Profiles in the Subcutaneous Adipose Tissues of Morbidly Obese Chinese Women. PMID:33550286
Conceptualization of functional single nucleotide polymorphisms of polycystic ovarian syndrome genes: an in silico approach. PMID:33506367
HumiR: Web Services, Tools and Databases for Exploring Human microRNA Data. PMID:33233537
Identification of Functional Genetic Variants Associated With Alcohol Dependence and Related Phenotypes Using a High-Throughput Assay. PMID:33119910
The effects of common variants in MDM2 and GNRH2 genes on the risk and survival of osteosarcoma in Han populations from Northwest China. PMID:32994424
miRNASNP-v3: a comprehensive database for SNPs and disease-related variations in miRNAs and miRNA targets. PMID:32990748
SIRT1 Gene SNP rs932658 Is Associated With Medication-Related Osteonecrosis of the Jaw. PMID:32967053
Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences. PMID:32867672
Critical Analysis of Genome-Wide Association Studies: Triple Negative Breast Cancer Quae Exempli Causa. PMID:32823908
Investigating the pathogenic SNPs in BLM helicase and their biological consequences by computational approach. PMID:32704157
Association of variants in selected genes mediating host immune response with duration of Staphylococcus aureus bacteremia. PMID:32507857
miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology. PMID:32484539
RNAseq-Based Prioritization Revealed COL6A5, COL8A1, COL10A1 and MIR146A as Common and Differential Susceptibility Biomarkers for Psoriasis and Psoriatic Arthritis: Confirmation from Genotyping Analysis of 1417 Italian Subjects. PMID:32326527
dbMTS: A comprehensive database of putative human microRNA target site SNVs and their functional predictions. PMID:32227657
ErbB4 3'-UTR Variant (c.*3622A>G) is Associated with ER/PR Negativity and Advanced Breast Cancer. PMID:32071504
An in silico approach to characterize nonsynonymous SNPs and regulatory SNPs in human TOX3 gene. PMID:31819019
Reduced expression of microRNA-139-5p in hepatocellular carcinoma results in a poor outcome: An exploration the roles of microRNA-139-5p in tumorigenesis, advancement and prognosis at the molecular biological level using an integrated meta-analysis and bioinformatic investigation. PMID:31807180
Identification and analysis of pathogenic nsSNPs in human LSP1 gene. PMID:31787810
Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant. PMID:31699989
miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database. PMID:31691816
MicroRNA-744/transforming growth factor β1 relationship regulates liver cirrhosis. PMID:31643031
In Silico Genetics Revealing 5 Mutations in CEBPA Gene Associated With Acute Myeloid Leukemia. PMID:31621694
PopTargs: a database for studying population evolutionary genetics of human microRNA target sites. PMID:31608947
The variability of SMCHD1 gene in FSHD patients: evidence of new mutations. PMID:31600781
Structural, functional and molecular dynamics analysis of cathepsin B gene SNPs associated with tropical calcific pancreatitis, a rare disease of tropics. PMID:31592339
Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders. PMID:31477794
An Approach to Identify Individual Functional Single Nucleotide Polymorphisms and Isoform MicroRNAs. PMID:31467902
Whole genome and transcriptome sequencing of post-mortem cardiac tissues from sudden cardiac death victims identifies a gene regulatory variant in NEXN. PMID:31392414
SNP rs4937333 in the miRNA-5003-Binding Site of the ETS1 3'-UTR Decreases ETS1 Expression. PMID:31275358
The Impact of Population Variation in the Analysis of microRNA Target Sites. PMID:31234531
miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. PMID:31211169
Gain-of-Function Mutations: An Emerging Advantage for Cancer Biology. PMID:31047772
The Interplay between miRNA-Related Variants and Age-Related Macular Degeneration: EVIDENCE of Association of MIR146A and MIR27A. PMID:30934838
A DAAM1 3'-UTR SNP mutation regulates breast cancer metastasis through affecting miR-208a-5p-DAAM1-RhoA axis. PMID:30911286
Relationship of common variants in Interleukin 33 gene with susceptibility and prognosis of osteosarcoma in Han Chinese population. PMID:30854122
SNPs rs10224002 in PRKAG2 may disturb gene expression and consequently affect hypertension. PMID:30689184
Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data. PMID:30564131
regQTLs: Single nucleotide polymorphisms that modulate microRNA regulation of gene expression in tumors. PMID:30557297
miRNA Mediated Noise Making of 3'UTR Mutations in Cancer. PMID:30424545
Framework for microRNA variant annotation and prioritization using human population and disease datasets. PMID:30302893
Uncovering association networks through an eQTL analysis involving human miRNAs and lincRNAs. PMID:30301969
MIR4532 gene variant rs60432575 influences the expression of KCNJ11 and the sulfonylureas-stimulated insulin secretion. PMID:30242599
MicroRNA-17 as a promising diagnostic biomarker of gastric cancer: An investigation combining TCGA, GEO, meta-analysis, and bioinformatics. PMID:30186751
Polymorphism studies on microRNA targetome of thalassemia. PMID:30108424
Trends in the development of miRNA bioinformatics tools. PMID:29982332
PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites. PMID:29963077
MicroRNA-Related Genetic Variants Associated with Survival of Head and Neck Squamous Cell Carcinoma. PMID:29880533
Integrative Analysis Identifies Genetic Variants Associated With Autoimmune Diseases Affecting Putative MicroRNA Binding Sites. PMID:29755505
Clustering Pattern and Functional Effect of SNPs in Human miRNA Seed Regions. PMID:29693000
A Comprehensive in Silico Analysis of Regulatory SNPs of Human CLEC7A Gene and Its Validation as Genotypic and Phenotypic Disease Marker in Recurrent Vulvovaginal Infections. PMID:29616193
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes. PMID:29563329
A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality. PMID:29457789
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. PMID:29304378
Genetic variation at the microRNA binding site of CAV1 gene is associated with lung cancer susceptibility. PMID:29190968
Significance of functional disease-causal/susceptible variants identified by whole-genome analyses for the understanding of human diseases. PMID:29129848
MSDD: a manually curated database of experimentally supported associations among miRNAs, SNPs and human diseases. PMID:29106642
The rs2910164 variant is associated with reduced miR-146a expression but not cytokine levels in patients with type 2 diabetes. PMID:29058209
A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma. PMID:29049738
Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs. PMID:28960269
Association between polymorphisms in microRNA target sites and survival in early-stage non-small cell lung cancer. PMID:28922562
Structure and functional impact of seed region variant in MIR-499 gene family in bronchial asthma. PMID:28886711
The correlation between CRB1 variants and the clinical severity of Brazilian patients with different inherited retinal dystrophy phenotypes. PMID:28819299
CXCL9-11 polymorphisms are associated with liver fibrosis in patients with chronic hepatitis C: a cross-sectional study. PMID:28755163
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. PMID:28743860
Phenotype prediction for mucopolysaccharidosis type I by in silico analysis. PMID:28676128
Systematic Prediction of the Impacts of Mutations in MicroRNA Seed Sequences. PMID:28637929
Genome-scale identification of microRNA-related SNPs associated with risk of head and neck squamous cell carcinoma. PMID:28582492
An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations. PMID:28480217
SNPs in microRNA target sites and their potential role in human disease. PMID:28381629
Functional variomics and network perturbation: connecting genotype to phenotype in cancer. PMID:28344341
Computational Modeling of complete HOXB13 protein for predicting the functional effect of SNPs and the associated role in hereditary prostate cancer. PMID:28272408
A functional variant in the 3'-UTR of VEGF predicts the 90-day outcome of ischemic stroke in Chinese patients. PMID:28234972
miRNAs target databases: developmental methods and target identification techniques with functional annotations. PMID:28204845
Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts. PMID:28171541
Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response. PMID:28115488
Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis. PMID:27890468
A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility. PMID:27759029
MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study. PMID:27701053
Alu-miRNA interactions modulate transcript isoform diversity in stress response and reveal signatures of positive selection. PMID:27586304
Interaction Between Peroxisome Proliferator Activated Receptor δ and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population. PMID:27530449
A Bioinformatics Approach to Prioritize Single Nucleotide Polymorphisms in TLRs Signaling Pathway Genes. PMID:27478803
Bioinformatics Approach for Prediction of Functional Coding/Noncoding Simple Polymorphisms (SNPs/Indels) in Human BRAF Gene. PMID:27478437
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. PMID:27432226
A 3'UTR polymorphism marks differential KLRG1 mRNA levels through disruption of a miR-584-5p binding site and associates with pemphigus foliaceus susceptibility. PMID:27424220
A comprehensive in silico analysis of non-synonymous and regulatory SNPs of human MBL2 gene. PMID:27390651
In silico analysis of deleterious single nucleotide polymorphisms in human BUB1 mitotic checkpoint serine/threonine kinase B gene. PMID:27331020
microRNA editing in seed region aligns with cellular changes in hypoxic conditions. PMID:27298257
Separating the wheat from the chaff: systematic identification of functionally relevant noncoding variants in ADHD. PMID:27113999
Mining of single nucleotide polymorphisms in the 3' untranslated region of liver cancer-implicated miR-122 target genes. PMID:27047961
A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism. PMID:27046647
A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer. PMID:26893365
Bioinformatics Resources for MicroRNA Discovery. PMID:26819547
Identification of critical variants within SLC44A4, an ulcerative colitis susceptibility gene identified in a GWAS in north Indians. PMID:26741288
Double-strand break repair and colorectal cancer: gene variants within 3' UTRs and microRNAs binding as modulators of cancer risk and clinical outcome. PMID:26735576
Differential gene expression levels might explain association of LAIR2 polymorphisms with pemphigus. PMID:26721477
GWASdb v2: an update database for human genetic variants identified by genome-wide association studies. PMID:26615194
Bioinformatic tools for microRNA dissection. PMID:26578605
SomamiR 2.0: a database of cancer somatic mutations altering microRNA-ceRNA interactions. PMID:26578591
Knowledge-based analysis of functional impacts of mutations in microRNA seed regions. PMID:26564979
microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment. PMID:26501795
Altered Gene Expression Associated with microRNA Binding Site Polymorphisms. PMID:26496489
miRVaS: a tool to predict the impact of genetic variants on miRNAs. PMID:26384425
The genetics of human autoimmune disease: A perspective on progress in the field and future directions. PMID:26343334
Polymorphism in microRNA-binding site in HNF1B influences the susceptibility of type 2 diabetes mellitus: a population based case-control study. PMID:26329304
Genetic variants in microRNA genes: impact on microRNA expression, function, and disease. PMID:26052338
An update of miRNASNP database for better SNP selection by GWAS data, miRNA expression and online tools. PMID:25877638
Biological databases for human research. PMID:25712261
Overview of microRNA biology. PMID:25632930
Genetic variability of microRNA regulome in human. PMID:25629077
Multi-ethnic analysis reveals soluble L-selectin may be post-transcriptionally regulated by 3'UTR polymorphism: the Multi-Ethnic Study of Atherosclerosis (MESA). PMID:25576479
In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci. PMID:25552398
Genetic variants in let-7/Lin28 modulate the risk of oral cavity cancer in a Chinese Han population. PMID:25503985
Heterogeneity and individuality: microRNAs in mental disorders. PMID:25395183
CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits. PMID:25368670
lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse. PMID:25332392
Polymorphisms in HLA-DPB1 are associated with differences in rubella virus-specific humoral immunity after vaccination. PMID:25293367
Single-Nucleotide Polymorphisms Within MicroRNAs Sequences and Their 3' UTR Target Sites May Regulate Gene Expression in Gastrointestinal Tract Cancers. PMID:25237569
Polymorphism in miRNA-1 target site and circulating miRNA-1 phenotype are associated with the decreased risk and prognosis of coronary artery disease. PMID:25197382
Computational analysis of functional single nucleotide polymorphisms associated with the CYP11B2 gene. PMID:25102047
Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer. PMID:25054431
miR-485-5p binding site SNP rs8752 in HPGD gene is associated with breast cancer risk. PMID:25003827
Computational prediction of disease microRNAs in domestic animals. PMID:24970281
Genetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance. PMID:24926315
CREAM: a database for chemotherapy resistance-associated miRSNP. PMID:24874743
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits PubMed citations: 80.

80 articles citing: PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits

Application of the targeted sequencing approach reveals the single nucleotide polymorphism (SNP) repertoire in microRNA genes in the pig genome. PMID:33972633
Computational analysis of Cyclin D1 gene SNPs and association with breast cancer. PMID:33438725
Genome-Wide Analysis of MicroRNA-related Single Nucleotide Polymorphisms (SNPs) in Mouse Genome. PMID:32238847
Towards precision medicine: interrogating the human genome to identify drug pathways associated with potentially functional, population-differentiated polymorphisms. PMID:31578463
Architecture of polymorphisms in the human genome reveals functionally important and positively selected variants in immune response and drug transporter genes. PMID:30219098
Lack of Evidence of the Role of APOA5 3'UTR Polymorphisms in Iranian Children and Adolescents with Metabolic Syndrome. PMID:29504307
A GDF15 3' UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p. PMID:28806401
Systematic Prediction of the Impacts of Mutations in MicroRNA Seed Sequences. PMID:28637929
An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations. PMID:28480217
Identification of a New Single-nucleotide Polymorphism within the Apolipoprotein A5 Gene, Which is Associated with Metabolic Syndrome. PMID:28401071
Functional variomics and network perturbation: connecting genotype to phenotype in cancer. PMID:28344341
miRNAs target databases: developmental methods and target identification techniques with functional annotations. PMID:28204845
Genome-wide identification of microRNA-related variants associated with risk of Alzheimer's disease. PMID:27328823
MiRNA-Related Genetic Variations Associated with Radiotherapy-Induced Toxicities in Patients with Locally Advanced Non-Small Cell Lung Cancer. PMID:26991123
SomamiR 2.0: a database of cancer somatic mutations altering microRNA-ceRNA interactions. PMID:26578591
Knowledge-based analysis of functional impacts of mutations in microRNA seed regions. PMID:26564979
Altered Gene Expression Associated with microRNA Binding Site Polymorphisms. PMID:26496489
Micro-RNA Binding Site Polymorphisms in the WFS1 Gene Are Risk Factors of Diabetes Mellitus. PMID:26426397
Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies. PMID:25941324
Genetic variants in miRNA processing genes and pre-miRNAs are associated with the risk of chronic lymphocytic leukemia. PMID:25793711
Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer. PMID:25480945
MicroRNA-binding site polymorphisms in hematological malignancies. PMID:25421940
CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits. PMID:25368670
Functional relevance for multiple sclerosis-associated genetic variants. PMID:25308886
Computational Methods for MicroRNA Target Prediction. PMID:25153283
Single Nucleotide Polymorphisms Associated with MicroRNA Regulation. PMID:24970168
Genetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance. PMID:24926315
Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding. PMID:24886876
Pharmacogenetics of microRNAs and microRNAs biogenesis machinery in pediatric acute lymphoblastic leukemia. PMID:24614921
Influence of genetic polymorphisms involved in the hypothalamic-pituitary-adrenal axis and their interactions with environmental factors on antidepressant response. PMID:24422887
rSNPBase: a database for curated regulatory SNPs. PMID:24285297
Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant. PMID:24216480
PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways. PMID:24163105
Emerging roles for miRNAs in the development, diagnosis, and treatment of diabetic nephropathy. PMID:23666892
MicroRNA-related genetic variants associated with clinical outcomes in early-stage non-small cell lung cancer patients. PMID:23378343
Mapping of the IRF8 gene identifies a 3'UTR variant associated with risk of chronic lymphocytic leukemia but not other common non-Hodgkin lymphoma subtypes. PMID:23307532
Influence of genetic variants in type I interferon genes on melanoma survival and therapy. PMID:23209811
Impact of the Interaction between 3'-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes. PMID:23181071
SomamiR: a database for somatic mutations impacting microRNA function in cancer. PMID:23180788
MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of the common polymorphic variant rs9024. PMID:23133646
Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes. PMID:23091610
Systematic analysis of microRNA targeting impacted by small insertions and deletions in human genome. PMID:23049969
Targeted pharmacogenetic analysis of antipsychotic response in the CATIE study. PMID:22920393
Mutations and binding sites of human transcription factors. PMID:22670148
Genetic architecture of microRNA expression: implications for the transcriptome and complex traits. PMID:22658545
MicroRNA target site polymorphisms in the VHL-HIF1α pathway predict renal cell carcinoma risk. PMID:22517515
Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection. PMID:22496856
MicroRNAs in stress signaling and human disease. PMID:22424228
Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis. PMID:22359580
miRNA-mediated relationships between Cis-SNP genotypes and transcript intensities in lymphocyte cell lines. PMID:22348086
A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy. PMID:22319602
miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes. PMID:22276777
In silico and in vitro identification of microRNAs that regulate hepatic nuclear factor 4α expression. PMID:22232426
Brain derived neurotrophic factor (BDNF) expression is regulated by microRNAs miR-26a and miR-26b allele-specific binding. PMID:22194877
PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits. PMID:22080514
A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. PMID:21995669
Inferring causative variants in microRNA target sites. PMID:21693556
Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer. PMID:21692980
MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium. PMID:21636674
In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes. PMID:21457141
dPORE-miRNA: polymorphic regulation of microRNA genes. PMID:21326606
Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection? PMID:20948563
MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets. PMID:20809528
Polymorphisms in predicted miRNA binding sites and osteoporosis. PMID:20641033
Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans. PMID:20587604
Associations between NBS1 polymorphisms, haplotypes and smoking-related cancers. PMID:20478923
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping. PMID:20377871
Oncoviruses and Pathogenic MicroRNAs in Humans. PMID:19920887
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. PMID:19727342
Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. PMID:19561119
Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes. PMID:19458495
Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression. PMID:19396161
MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. PMID:19290790
Advanced technologies for genomic analysis in farm animals and its application for QTL mapping. PMID:19093212
Association analysis of WNT10B with bone mass and structure among individuals of African ancestry. PMID:19016593
An optimized procedure for the design and evaluation of Ecotilling assays. PMID:18973671
Functional genetic variation of human miRNAs and phenotypic consequences. PMID:18787897
Combining transcriptional profiling and genetic linkage analysis to uncover gene networks operating in hematopoietic stem cells and their progeny. PMID:18560825
MicroRNA-206: the skeletal muscle-specific myomiR. PMID:18381085
Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction. PMID:18335026
PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits PubMed citations: 65.

65 articles citing: PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits

Prediction of Single-Nucleotide Polymorphisms within microRNAs Binding Sites of Neuronal Genes Related to Multiple Sclerosis: A Preliminary Study. PMID:33959565
Deciphering the Variants Located in the MIR196A2, MIR146A, and MIR423 with Type-2 Diabetes Mellitus in Pakistani Population. PMID:33925232
Polymorphisms in MicroRNA Target Sites of TGF-β Signaling Pathway Genes and Susceptibility to Allergic Rhinitis. PMID:33596578
The Computational Analysis Conducted on miRNA Target Sites in Association with SNPs at 3'UTR of ADHD-implicated Genes. PMID:31660846
Development of species specific putative miRNA and its target prediction tool in wheat (Triticum aestivum L.). PMID:30846812
Systematics for types and effects of DNA variations. PMID:30591019
Genetic effects of BDKRB2 and KNG1 on deep venous thrombosis after orthopedic surgery and the potential mediator. PMID:30478260
TLR10 and NFKBIA contributed to the risk of hip osteoarthritis: systematic evaluation based on Han Chinese population. PMID:29980729
Induction of the apoptotic pathway by oxidative stress in spontaneous preterm birth: Single nucleotide polymorphisms, maternal lifestyle factors and health status. PMID:29930809
Lack of Evidence of the Role of APOA5 3'UTR Polymorphisms in Iranian Children and Adolescents with Metabolic Syndrome. PMID:29504307
Systematic Prediction of the Impacts of Mutations in MicroRNA Seed Sequences. PMID:28637929
Identification of a New Single-nucleotide Polymorphism within the Apolipoprotein A5 Gene, Which is Associated with Metabolic Syndrome. PMID:28401071
Functional variomics and network perturbation: connecting genotype to phenotype in cancer. PMID:28344341
miRNAs target databases: developmental methods and target identification techniques with functional annotations. PMID:28204845
A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility. PMID:27759029
Identification of critical variants within SLC44A4, an ulcerative colitis susceptibility gene identified in a GWAS in north Indians. PMID:26741288
Bioinformatic tools for microRNA dissection. PMID:26578605
SomamiR 2.0: a database of cancer somatic mutations altering microRNA-ceRNA interactions. PMID:26578591
Knowledge-based analysis of functional impacts of mutations in microRNA seed regions. PMID:26564979
Principles of miRNA-mRNA interactions: beyond sequence complementarity. PMID:26037721
Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies. PMID:25941324
An update of miRNASNP database for better SNP selection by GWAS data, miRNA expression and online tools. PMID:25877638
Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome. PMID:25867973
Systems Medicine 2.0: potential benefits of combining electronic health care records with systems science models. PMID:25831125
SubmiRine: assessing variants in microRNA targets using clinical genomic data sets. PMID:25813044
Genetic variants in miRNA processing genes and pre-miRNAs are associated with the risk of chronic lymphocytic leukemia. PMID:25793711
GRASP v2.0: an update on the Genome-Wide Repository of Associations between SNPs and phenotypes. PMID:25428361
CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits. PMID:25368670
MicroRNA polymorphisms and risk of colorectal cancer. PMID:25342389
Polymorphism in miRNA-1 target site and circulating miRNA-1 phenotype are associated with the decreased risk and prognosis of coronary artery disease. PMID:25197382
Identifying a polymorphic 'switch' that influences miRNAs' regulation of a myasthenia gravis risk pathway. PMID:25118158
MicroRNA in teleost fish. PMID:25053657
Genetic association of osteopontin (OPN) and its receptor CD44 genes with susceptibility to Chinese gastric cancer patients. PMID:25009318
Computational prediction of disease microRNAs in domestic animals. PMID:24970281
Single Nucleotide Polymorphisms Associated with MicroRNA Regulation. PMID:24970168
Identification of putative pathogenic SNPs implied in schizophrenia-associated miRNAs. PMID:24934851
Genetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance. PMID:24926315
LincSNP: a database of linking disease-associated SNPs to human large intergenic non-coding RNAs. PMID:24885522
Mining the 3'UTR of autism-implicated genes for SNPs perturbing microRNA regulation. PMID:24747189
mrSNP: software to detect SNP effects on microRNA binding. PMID:24629096
Single nucleotide polymorphism-specific regulation of matrix metalloproteinase-9 by multiple miRNAs targeting the coding exon. PMID:24627221
Pharmacogenetics of microRNAs and microRNAs biogenesis machinery in pediatric acute lymphoblastic leukemia. PMID:24614921
Genetic variants in microRNA target sites of 37 selected cancer-related genes and the risk of cervical cancer. PMID:24465869
Influence of genetic polymorphisms involved in the hypothalamic-pituitary-adrenal axis and their interactions with environmental factors on antidepressant response. PMID:24422887
Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites. PMID:24416147
Association of impulsivity and polymorphic microRNA-641 target sites in the SNAP-25 gene. PMID:24391914
rSNPBase: a database for curated regulatory SNPs. PMID:24285297
HMDD v2.0: a database for experimentally supported human microRNA and disease associations. PMID:24194601
PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways. PMID:24163105
Early growth response-2 signaling mediates immunomodulatory effects of human multipotential stromal cells. PMID:24007274
CXCR5 polymorphisms in non-Hodgkin lymphoma risk and prognosis. PMID:23812490
Candidate gene association studies: a comprehensive guide to useful in silico tools. PMID:23656885
SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers. PMID:23614619
Prioritization of genetic variants in the microRNA regulome as functional candidates in genome-wide association studies. PMID:23595788
Needles in the genetic haystack of lipid disorders: single nucleotide polymorphisms in the microRNA regulome. PMID:23505316
SomamiR: a database for somatic mutations impacting microRNA function in cancer. PMID:23180788
MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs. PMID:23173617
MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of the common polymorphic variant rs9024. PMID:23133646
Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes. PMID:23091610
Systematic analysis of microRNA targeting impacted by small insertions and deletions in human genome. PMID:23049969
Haploinsufficiency of Tumor Suppressor Genes is Driven by the Cumulative Effect of microRNAs, microRNA Binding Site Polymorphisms and microRNA Polymorphisms: An In silico Approach. PMID:23032637
Targeted pharmacogenetic analysis of antipsychotic response in the CATIE study. PMID:22920393
Cross talk between microRNA and coding cancer genes. PMID:22647358
Catalog of microRNA seed polymorphisms in vertebrates. PMID:22303453
3'-UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans. PMID:22282660
http://dx.doi.org/10.1093/nar/gkt1028

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gene silencing by mirna (microrna)
metasource: Fairsharing.org
version: FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

genetic polymorphism
metasource: Fairsharing.org
version: FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

micro rna
metasource: Fairsharing.org
version: FAIRsharing.org: PolymiRTS; Polymorphism in microRNAs and their TargetSites; DOI: https://doi.org/10.25504/FAIRsharing.4bt49f; Last edited: May 20, 2021, 1:41 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

nucleotide sequence databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

coding and non-coding dna
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

functional, regulatory and non-coding rna
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

genetic variation
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

dna polymorphism
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

pathology
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:07.993116

gene silencing by mirna (microrna) polymorphism micro rna nucleic acid sequence coding and non-coding dna functional, regulatory and non-coding rna genetic variation dna polymorphism pathology small molecule

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miRNASNP-v3

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TarBase

microRNA.org

mESAdb

miRGator v2.0

miRNEST

miRBase

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miRmap

miRPathDB

StarBASE

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Database of Single Nucleotide Polymorphism

lncRNASNP

miRTarBase

TransmiR