MirGeneDB.org
Names
More detailed information about this field from each metasource.
MirGeneDB.org
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
MirGeneDB
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:33.563677
MirGeneDB 2.0: the metazoan microRNA complement
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
mirgen
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:33.563677
Names
More detailed information about this field from each metasource.
MirGeneDB.org
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
MirGeneDB
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:33.563677
MirGeneDB 2.0: the metazoan microRNA complement
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
mirgen
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:35:33.563677
Other names: MirGeneDB, MirGeneDB 2.0: the metazoan microRNA complement, mirgen
Names
More detailed information about this field from each metasource.
MirGeneDB.org
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
MirGeneDB
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:33.563677
MirGeneDB 2.0: the metazoan microRNA complement
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
mirgen
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:35:33.563677
MirGeneDB is a database of microRNA genes that have been validated and annotated as described in "A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome".* The initial version contained 1,434 microRNA genes for human, mouse, chicken and zebrafish. Version 2.0 contains more than 10,000 genes from 45 organisms representing nearly every major metazoan group, and these microRNAs can be browsed, searched and downloaded.
Description
More detailed information about this field from each metasource.
MirGeneDB is a database of microRNA genes that have been validated and annotated as described in "A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome".* The initial version contained 1,434 microRNA genes for human, mouse, chicken and zebrafish. Version 2.0 contains more than 10,000 genes from 45 organisms representing nearly every major metazoan group, and these microRNAs can be browsed, searched and downloaded.
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
Small non-coding RNAs have gained substantial attention due to their roles in animal development and human disorders. Among them, microRNAs are special because individual gene sequences are conserved across the animal kingdom. In addition, unique and mechanistically well understood features can clearly distinguish bona fide miRNAs from the myriad other small RNAs generated by cells. However, making this distinction is not a common practice and, thus, not surprisingly, the heterogeneous quality of available miRNA complements has become a major concern in microRNA research. We addressed this by extensively expanding our curated microRNA gene database - MirGeneDB - to 45 organisms, encompassing a wide phylogenetic swath of animal evolution. By consistently annotating and naming 10,899 microRNA genes in these organisms, we show that previous microRNA annotations contained not only many false positives, but surprisingly lacked >2000 bona fide microRNAs. Indeed, curated microRNA complements of closely related organisms are very similar and can be used to reconstruct ancestral miRNA repertoires. MirGeneDB represents a robust platform for microRNA-based research, providing deeper and more significant insights into the biology and evolution of miRNAs as well as biomedical and biomarker research.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
A miRBase derived database for microRNA genes that have been validated and annotated. Currently microRNA genes are available for human, mouse, chicken and zebrafish and can be browsed, blasted and downloaded.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:35:33.563677
Webpage:
http://mirgenedb.orgWebpage
More detailed information about this field from each metasource.
http://mirgenedb.org
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
http://mirgenedb.org/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:33.563677
Publications:
Publications
More detailed information about this field from each metasource.
A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
PMID: 26473382
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
MirGeneDB 2.0: the metazoan microRNA complement
PMID: 31598695
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
http://dx.doi.org/10.1101/258749
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
http://dx.doi.org/10.1093/nar/gkz885
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
http://dx.doi.org/10.1146/annurev-genet-120213-092023
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:33.563677
Publications
More detailed information about this field from each metasource.
A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
PMID: 26473382
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
MirGeneDB 2.0: the metazoan microRNA complement
PMID: 31598695
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
http://dx.doi.org/10.1101/258749
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
http://dx.doi.org/10.1093/nar/gkz885
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
http://dx.doi.org/10.1146/annurev-genet-120213-092023
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:35:33.563677
-
A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
PubMed citations: 233.
233 articles citing: A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
Lysophosphatidic Acid Signaling and microRNAs: New Roles in Various Cancers. PMID:35814375
De Novo Large Deletion Leading to Fragile X Syndrome. PMID:35646065
Identification of Functional CircRNA-miRNA-mRNA Regulatory Network in Dorsolateral Prefrontal Cortex Neurons of Patients With Cocaine Use Disorder. PMID:35493321
MicroRNA 3928 Suppresses Glioblastoma through Downregulation of Several Oncogenes and Upregulation of p53. PMID:35409289
Emerging Biomarkers of Multiple Sclerosis in the Blood and the CSF: A Focus on Neurofilaments and Therapeutic Considerations. PMID:35328802
Revealing key lncRNAs in cytogenetically normal acute myeloid leukemia by reconstruction of the lncRNA-miRNA-mRNA network. PMID:35322118
Signatures of genetic variation in human microRNAs point to processes of positive selection and population-specific disease risks. PMID:35249174
The limits of human microRNA annotation have been met. PMID:35236776
Flexible pri-miRNA structures enable tunable production of 5' isomiRs. PMID:35188062
Expression Profiles of Estrogen-Regulated MicroRNAs in Cancer Cells. PMID:35119673
Bioinformatic analysis of long non-coding RNA-associated competing endogenous RNA network in adrenocortical carcinoma. PMID:35116967
The Prognostic and Molecular Landscape of Autophagy-Related Long Noncoding RNA in Colorectal Cancer. PMID:35097120
Influence of feeder cells on transcriptomic analysis of pluripotent stem cells. PMID:35060660
Associations between the Levels of Estradiol-, Progesterone-, and Testosterone-Sensitive MiRNAs and Main Clinicopathologic Features of Breast Cancer. PMID:35055320
Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop. PMID:35047007
The embryonic transcriptome of Parhyale hawaiensis reveals different dynamics of microRNAs and mRNAs during the maternal-zygotic transition. PMID:34996916
Comprehensive analysis of the LncRNAs, MiRNAs, and MRNAs acting within the competing endogenous RNA network of LGG. PMID:34993720
miRMut: Annotation of mutations in miRNA genes from human whole-exome or whole-genome sequencing. PMID:34977675
Genome-Wide RNA-Sequencing Reveals Massive Circular RNA Expression Changes of the Neurotransmission Genes in the Rat Brain after Ischemia-Reperfusion. PMID:34946819
A Comparison of Reproductive Performances in Young and Old Females: A Case Study on the Atlantic Bluefin Tuna in the Mediterranean Sea. PMID:34944116
Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics. PMID:34884848
MicroRNAs as Indicators into the Causes and Consequences of Whole-Genome Duplication Events. PMID:34865078
MirGeneDB 2.1: toward a complete sampling of all major animal phyla. PMID:34850127
Identification of an Immune-Related Biomarker Model Based on the CircRNA-Associated Regulatory Network for Esophageal Carcinoma. PMID:34840568
Screening and Analysis of Key Genes in miRNA-mRNA Regulatory Network of Membranous Nephropathy. PMID:34824764
The conserved single-cleavage mechanism of animal DROSHA enzymes. PMID:34824450
A Rapid Evolving microRNA Cluster Rewires Its Target Regulatory Networks in Drosophila. PMID:34777478
Bioinformatic Tools for the Analysis and Prediction of ncRNA Interactions. PMID:34768830
Predicting functional circular RNA-based competitive endogenous RNA network in gastric carcinoma using novel bioinformatics analysis. PMID:34617801
Role of non-coding RNAs in tumor progression and metastasis in pancreatic cancer. PMID:34591242
Identification of Three Potential circRNA Biomarkers of Polycystic Ovary Syndrome by Bioinformatics Analysis and Validation. PMID:34588800
Role of competitive endogenous RNA networks in the pathogenesis of coronary artery disease. PMID:34532371
Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs. PMID:34502448
MicroRNA Databases and Tools. PMID:34432277
Investigation of Potential Molecular Biomarkers for Diagnosis and Prognosis of AFP-Negative HCC. PMID:34408477
Repression of Smad4 by MicroRNA-1285 moderates TGF-β-induced epithelial-mesenchymal transition in proliferative vitreoretinopathy. PMID:34383767
CRISPR/Cas13-Based Approaches for Ultrasensitive and Specific Detection of microRNAs. PMID:34359825
Small RNA expression and miRNA modification dynamics in human oocytes and early embryos. PMID:34340992
A Novel circRNA-miRNA-mRNA Hub Regulatory Network in Lung Adenocarcinoma. PMID:34306017
miRNA-Based Potential Biomarkers and New Molecular Insights in Ulcerative Colitis. PMID:34305614
New Genes Born-In or Invading Vertebrate Genomes. PMID:34295903
Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication. PMID:34289864
FBXL19‑AS1 promotes the progression of nasopharyngeal carcinoma by acting as a competing endogenous RNA to sponge miR‑431 and upregulate PBOV1. PMID:34278444
A hybrid CNN-LSTM model for pre-miRNA classification. PMID:34239004
RNA-sequencing of peripheral blood circular RNAs in Parkinson disease. PMID:34114985
Epigenetic-Based Therapy-A Prospective Chance for Medulloblastoma Patients' Recovery. PMID:34066495
Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma. PMID:34049287
Modeling Virus-Induced Inflammation in Zebrafish: A Balance Between Infection Control and Excessive Inflammation. PMID:34025644
microRNA-based diagnostic and therapeutic applications in cancer medicine. PMID:33998154
Network Analyses Predict Small RNAs That Might Modulate Gene Expression in the Testis and Epididymis of Bos indicus Bulls. PMID:33995471
microRNAs: New-Age Panacea in Cancer Therapeutics. PMID:33994728
Large-Scale Annotation and Evolution Analysis of MiRNA in Insects. PMID:33905491
miR-375 Promotes Pancreatic Differentiation In Vitro by Affecting Different Target Genes at Different Stages. PMID:33897780
Evolution after Whole-Genome Duplication: Teleost MicroRNAs. PMID:33871629
Digging into bivalve miRNAomes: between conservation and innovation. PMID:33813895
Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells. PMID:33806450
MicroRNA-mediated regulation of glucose and lipid metabolism. PMID:33772227
Sperm fate is promoted by the mir-44 microRNA family in the Caenorhabditis elegans hermaphrodite germline. PMID:33683352
miRNAture-Computational Detection of microRNA Candidates. PMID:33673400
A comparative analysis of heart microRNAs in vertebrates brings novel insights into the evolution of genetic regulatory networks. PMID:33663371
Conservation and turnover of miRNAs and their highly complementary targets in early branching animals. PMID:33622129
An Evaluation of the Fasciola hepatica miRnome Predicts a Targeted Regulation of Mammalian Innate Immune Responses. PMID:33584684
Non-Coding RNAs in the Transcriptional Network That Differentiates Skeletal Muscles of Sedentary from Long-Term Endurance- and Resistance-Trained Elderly. PMID:33546468
Transcriptomic analysis reveals essential microRNAs after peripheral nerve injury. PMID:33510094
Improvement, identification, and target prediction for miRNAs in the porcine genome by using massive, public high-throughput sequencing data. PMID:33493272
Regulatory Non-coding RNAs in Atherosclerosis. PMID:33454857
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes. PMID:33406242
Comprehensive Analysis of lncRNAs Related to the Prognosis of Esophageal Cancer Based on ceRNA Network and Cox Regression Model. PMID:33381546
Integrated Analysis of lncRNA-Mediated ceRNA Network Reveals a Prognostic Signature for Hepatocellular Carcinoma. PMID:33381151
Role of microRNAs in the pathophysiology of addiction. PMID:33336550
Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene. PMID:33323528
Unravelling the developmental and functional significance of an ancient Argonaute duplication. PMID:33273471
The Therapeutic Potential of MicroRNAs in Cancer: Illusion or Opportunity? PMID:33271894
MiR-320b/RAD21 axis affects hepatocellular carcinoma radiosensitivity to ionizing radiation treatment through DNA damage repair signaling. PMID:33251678
HumiR: Web Services, Tools and Databases for Exploring Human microRNA Data. PMID:33233537
A "Lymphocyte MicroRNA Signature" as Predictive Biomarker of Immunotherapy Response and Plasma PD-1/PD-L1 Expression Levels in Patients with Metastatic Renal Cell Carcinoma: Pointing towards Epigenetic Reprogramming. PMID:33207823
Pan-cancer analysis of somatic mutations in miRNA genes. PMID:33038763
MicroRNAs as Biomarkers in Canine Osteosarcoma: A New Future? PMID:33008041
Stumbling on elusive cargo: how isomiRs challenge microRNA detection and quantification, the case of extracellular vesicles. PMID:32944171
Parallel analysis of miRNAs and mRNAs suggests distinct regulatory networks in Crassostrea gigas infected by Ostreid herpesvirus 1. PMID:32912133
Comprehensive analysis of a long non-coding RNA-associated competing endogenous RNA network in glioma. PMID:32863896
The roles of microRNA in redox metabolism and exercise-mediated adaptation. PMID:32780693
Identification of circRNA-lncRNA-miRNA-mRNA Competitive Endogenous RNA Network as Novel Prognostic Markers for Acute Myeloid Leukemia. PMID:32751923
MicroRNAs and Apoptosis in Colorectal Cancer. PMID:32731413
MicroRNAs as Guardians of the Prostate: Those Who Stand before Cancer. What Do We Really Know about the Role of microRNAs in Prostate Biology? PMID:32645914
Comprehensive analysis of lncRNA-associated competing endogenous RNA network and immune infiltration in idiopathic pulmonary fibrosis. PMID:32642089
The human box C/D snoRNA U3 is a miRNA source and miR-U3 regulates expression of sortin nexin 27. PMID:32609813
Analysis of Circular RNA-Related Competing Endogenous RNA Identifies the Immune-Related Risk Signature for Colorectal Cancer. PMID:32582276
Construction of a Competitive Endogenous RNA Network for Pancreatic Adenocarcinoma Based on Weighted Gene Co-expression Network Analysis and a Prognosis Model. PMID:32548103
Comprehensive Analysis of Competing Endogenous RNA (ceRNA) Network Based on RNAs Differentially Expressed in Lung Adenocarcinoma Using The Cancer Genome Atlas (TCGA) Database. PMID:32533823
Clues of in vivo nuclear gene regulation by mitochondrial short non-coding RNAs. PMID:32427953
Role of microRNAs in the predisposition to gastrointestinal malignancies. PMID:32420299
Differential blood miRNA expression in brain amyloid imaging-defined Alzheimer's disease and controls. PMID:32414413
Recent Trends of microRNA Significance in Pediatric Population Glioblastoma and Current Knowledge of Micro RNA Function in Glioblastoma Multiforme. PMID:32349263
Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation. PMID:32326592
microRNAs in the Antitumor Immune Response and in Bone Metastasis of Breast Cancer: From Biological Mechanisms to Therapeutics. PMID:32316552
Toxic-Metal-Induced Alteration in miRNA Expression Profile as a Proposed Mechanism for Disease Development. PMID:32272672
Discovering Cancer-Related miRNAs from miRNA-Target Interactions by Support Vector Machines. PMID:32160711
Comprehensive Analysis of lncRNA-Mediated ceRNA Crosstalk and Identification of Prognostic Biomarkers in Wilms' Tumor. PMID:32149111
MiR-140 inhibits classical swine fever virus replication by targeting Rab25 in swine umbilical vein endothelial cells. PMID:32114898
Micro RNA Molecules as Modulators of Treatment Resistance, Immune Checkpoints Controllers and Sensitive Biomarkers in Glioblastoma Multiforme. PMID:32098401
A guide to naming human non-coding RNA genes. PMID:32090359
Leptin-Responsive MiR-4443 Is a Small Regulatory RNA Independent of the Canonic MicroRNA Biogenesis Pathway. PMID:32069948
Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. PMID:32009885
BioSeqZip: a collapser of NGS redundant reads for the optimization of sequence analysis. PMID:31999333
miR-181a-5p is downregulated and inhibits proliferation and the cell cycle in prostate cancer. PMID:31949785
SNHG16 Silencing Inhibits Neuroblastoma Progression by Downregulating HOXA7 via Sponging miR-128-3p. PMID:31919621
A lab-on-a-chip for rapid miRNA extraction. PMID:31856234
Small RNAs in parasitic nematodes - forms and functions. PMID:31843030
Edaravone reduces oxidative stress and intestinal cell apoptosis after burn through up-regulating miR-320 expression. PMID:31829167
X-linked miR-506 family miRNAs promote FMRP expression in mouse spermatogonia. PMID:31808593
Circular RNA-Associated Competing Endogenous RNA Network and Prognostic Nomogram for Patients With Colorectal Cancer. PMID:31781492
The Role of Non-coding RNAs in Oncology. PMID:31730848
Identification of breast cancer-related circRNAs by analysis of microarray and RNA-sequencing data: An observational study. PMID:31725681
A gene regulatory network to control EMT programs in development and disease. PMID:31712603
The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective. PMID:31709179
MicroRNAs in Daphnia magna identified and characterized by deep sequencing, genome mapping and manual curation. PMID:31685896
Identification of Candidate Biomarkers and Analysis of Prognostic Values in Oral Squamous Cell Carcinoma. PMID:31681590
Potential applications of microRNA profiling to forensic investigations. PMID:31658993
Circulating miRNAs as Diagnostic and Prognostic Biomarkers in Common Solid Tumors: Focus on Lung, Breast, Prostate Cancers, and Osteosarcoma. PMID:31614612
MirGeneDB 2.0: the metazoan microRNA complement. PMID:31598695
UPF1/SMG7-dependent microRNA-mediated gene regulation. PMID:31519907
Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API. PMID:31504201
A Complete Pipeline for Isolating and Sequencing MicroRNAs, and Analyzing Them Using Open Source Tools. PMID:31498311
miRNA-mRNA Associated With Survival in Endometrial Cancer. PMID:31481972
Integrated analysis of circular RNA-associated ceRNA network in cervical cancer: Observational Study. PMID:31441876
Prognostic value of genome-wide DNA methylation patterns in noncoding miRNAs and lncRNAs in uveal melanomas. PMID:31433788
Identification of candidate genes and miRNAs associated with neuropathic pain induced by spared nerve injury. PMID:31432094
Molecular network-based identification of competing endogenous RNAs in bladder cancer. PMID:31369587
Identification of circRNA-miRNA-mRNA regulatory network in gastric cancer by analysis of microarray data. PMID:31346318
miRBaseMiner, a tool for investigating miRBase content. PMID:31251108
Integrated analysis of a competing endogenous RNA network in renal cell carcinoma using bioinformatics tools. PMID:31213578
ceRNA network analysis reveals prognostic markers for glioblastoma. PMID:31186776
Somatic Mutations in miRNA Genes in Lung Cancer-Potential Functional Consequences of Non-Coding Sequence Variants. PMID:31181801
Functional analysis of lncRNAs based on competitive endogenous RNA in tongue squamous cell carcinoma. PMID:31179185
sRNAbench and sRNAtoolbox 2019: intuitive fast small RNA profiling and differential expression. PMID:31114926
Celebrating 25 Years of MicroRNA Research: From Discovery to Clinical Application. PMID:31018550
Circulating miRNA Signature as a Potential Biomarker for the Prediction of Analgesic Efficacy of Hydromorphone. PMID:30987164
IsomiRs: Expanding the miRNA repression toolbox beyond the seed. PMID:30953728
Too Many False Targets for MicroRNAs: Challenges and Pitfalls in Prediction of miRNA Targets and Their Gene Ontology in Model and Non-model Organisms. PMID:30919506
Comprehensive analysis of a ceRNA network reveals potential prognostic cytoplasmic lncRNAs involved in HCC progression. PMID:30916406
Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response. PMID:30862609
miRNA analysis with Prost! reveals evolutionary conservation of organ-enriched expression and post-transcriptional modifications in three-spined stickleback and zebrafish. PMID:30850632
An estimate of the total number of true human miRNAs. PMID:30820533
miR‑146a‑5p targets TCSF and influences cell growth and apoptosis to repress NSCLC progression. PMID:30816543
Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha). PMID:30813358
Comprehensive analysis of lncRNA-associated competing endogenous RNA network in tongue squamous cell carcinoma. PMID:30755833
Nucleotide-level Convolutional Neural Networks for Pre-miRNA Classification. PMID:30679648
Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires. PMID:30625327
Bias-minimized quantification of microRNA reveals widespread alternative processing and 3' end modification. PMID:30605524
Poly(A)-specific ribonuclease sculpts the 3' ends of microRNAs. PMID:30591540
Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity. PMID:30567465
Circular RNA regulatory network reveals cell-cell crosstalk in acute myeloid leukemia extramedullary infiltration. PMID:30558617
Discovery and validation of blood microRNAs as molecular biomarkers of epilepsy: Ways to close current knowledge gaps. PMID:30525113
Chondrosarcoma: biology, genetics, and epigenetics. PMID:30519452
Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity. PMID:30518766
miRTrace reveals the organismal origins of microRNA sequencing data. PMID:30514392
Profiling microRNA expression in Atlantic killifish (Fundulus heteroclitus) gill and responses to arsenic and hyperosmotic stress. PMID:30476744
miRBase: from microRNA sequences to function. PMID:30423142
Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy. PMID:30396857
Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis. PMID:30384176
Competing Endogenous RNA Regulations in Neurodegenerative Disorders: Current Challenges and Emerging Insights. PMID:30344479
Opportunities for microRNAs in the Crowded Field of Cardiovascular Biomarkers. PMID:30332561
Potential Role of miRNAs as Theranostic Biomarkers of Epilepsy. PMID:30321815
Unicellular Origin of the Animal MicroRNA Machinery. PMID:30318349
Predicting microRNA targeting efficacy in Drosophila. PMID:30286781
Non-coding RNA fragments account for the majority of annotated piRNAs expressed in somatic non-gonadal tissues. PMID:30271890
Large scale changes in the transcriptome of Eisenia fetida during regeneration. PMID:30260966
miRge 2.0 for comprehensive analysis of microRNA sequencing data. PMID:30153801
Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease. PMID:30089721
Regulation of Ion Channels by MicroRNAs and the Implication for Epilepsy. PMID:30046905
Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis. PMID:30037718
Comprehensive analysis of competitive endogenous RNAs network associated with head and neck squamous cell carcinoma. PMID:30002503
Trends in the development of miRNA bioinformatics tools. PMID:29982332
MicroRNA Control of TGF-β Signaling. PMID:29958433
xMD-miRNA-seq to generate near in vivo miRNA expression estimates in colon epithelial cells. PMID:29955168
Dimerization confers increased stability to nucleases in 5' halves from glycine and glutamic acid tRNAs. PMID:29893896
RegenDbase: a comparative database of noncoding RNA regulation of tissue regeneration circuits across multiple taxa. PMID:29872545
MicroRNA and cellular targets profiling reveal miR-217 and miR-576-3p as proviral factors during Oropouche infection. PMID:29813068
Human microRNAs preferentially target genes with intermediate levels of expression and its formation by mammalian evolution. PMID:29795674
Well-Annotated microRNAomes Do Not Evidence Pervasive miRNA Loss. PMID:29788279
MicroRNA-192-5p suppresses the initiation and progression of osteosarcoma by targeting USP1. PMID:29731868
The Potential Role of Platelet-Related microRNAs in the Development of Cardiovascular Events in High-Risk Populations, Including Diabetic Patients: A Review. PMID:29615970
A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97. PMID:29599847
Phase Transitions in the Assembly and Function of Human miRISC. PMID:29576456
Metazoan MicroRNAs. PMID:29570994
Target-enrichment sequencing for detailed characterization of small RNAs. PMID:29565901
Are microRNAs Important Players in HIV-1 Infection? An Update. PMID:29510515
Comparing miRNA structure of mirtrons and non-mirtrons. PMID:29504892
Recently Evolved Tumor Suppressor Transcript TP73-AS1 Functions as Sponge of Human-Specific miR-941. PMID:29474580
Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay. PMID:29410437
Big Strides in Cellular MicroRNA Expression. PMID:29361313
Revisiting Criteria for Plant MicroRNA Annotation in the Era of Big Data. PMID:29343505
A comprehensive profile of circulating RNAs in human serum. PMID:29219730
Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets. PMID:29165639
Identification of cell cycle-targeting microRNAs through genome-wide screens. PMID:29099267
Sex-biased microRNA expression in mammals and birds reveals underlying regulatory mechanisms and a role in dosage compensation. PMID:29079676
Analysis of miRNA expression profile induced by short term starvation in breast cancer cells treated with doxorubicin. PMID:29069757
sRNAnalyzer-a flexible and customizable small RNA sequencing data analysis pipeline. PMID:29069500
Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization. PMID:29051527
miRCarta: a central repository for collecting miRNA candidates. PMID:29036653
Comparative analysis of miRNA expression during the development of insects of different metamorphosis modes and germ-band types. PMID:29020923
Identification of Circulating miRNAs Differentially Regulated by Opioid Treatment. PMID:28926935
Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs. PMID:28911107
Toward the human cellular microRNAome. PMID:28877962
Ancient human miRNAs are more likely to have broad functions and disease associations than young miRNAs. PMID:28859623
Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b. PMID:28848235
On the performance of pre-microRNA detection algorithms. PMID:28839141
An integrated expression atlas of miRNAs and their promoters in human and mouse. PMID:28829439
Improving the Quality of Positive Datasets for the Establishment of Machine Learning Models for pre-microRNA Detection. PMID:28753538
Identification and characterization of the Chinese giant salamander (Andrias davidianus) miRNAs by deep sequencing and predication of their targets. PMID:28695491
Towards a Consistent, Quantitative Evaluation of MicroRNA Evolution. PMID:28637930
Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus. PMID:28607431
The evolutionary origin of plant and animal microRNAs. PMID:28529980
MicroRNAs in injury and repair. PMID:28501916
Coordinated Actions of MicroRNAs with other Epigenetic Factors Regulate Skeletal Muscle Development and Adaptation. PMID:28420141
Unveiling the Impact of the Genomic Architecture on the Evolution of Vertebrate microRNAs. PMID:28377786
Delineating the impact of machine learning elements in pre-microRNA detection. PMID:28367373
Rapid Evolution of microRNA Loci in the Brown Algae. PMID:28338896
Manipulating MicroRNAs in Murine Models: Targeting the Multi-Targeting in Epilepsy. PMID:28331471
Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients. PMID:28293063
miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1. PMID:28239298
Downregulation of miR-130b~301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer. PMID:28166834
Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts. PMID:28062594
The microRNA toolkit of insects. PMID:27883064
MiRNAs and miRNA Polymorphisms Modify Drug Response. PMID:27834829
HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing. PMID:27425409
Pervasive microRNA Duplication in Chelicerates: Insights from the Embryonic microRNA Repertoire of the Spider Parasteatoda tepidariorum. PMID:27324919
microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes. PMID:27189568
Managing Pancreatic Adenocarcinoma: A Special Focus in MicroRNA Gene Therapy. PMID:27187371
MicroRNA regulation of macrophages in human pathologies. PMID:27137182
Host gene constraints and genomic context impact the expression and evolution of human microRNAs. PMID:27109497
The miRNA biogenesis in marine bivalves. PMID:26989613 -
MirGeneDB 2.0: the metazoan microRNA complement
PubMed citations: 68.
68 articles citing: MirGeneDB 2.0: the metazoan microRNA complement
Epigenetic Aspects and Prospects in Autoimmune Hepatitis. PMID:35844554
Circulating MicroRNAs as a Tool for Diagnosis of Liver Disease Progression in People Living with HIV-1. PMID:35746590
Discovery and validation of human genomic safe harbor sites for gene and cell therapies. PMID:35474867
Secondary structure RNA elements control the cleavage activity of DICER. PMID:35440644
An Alternative Class of Targets for microRNAs Containing CG Dinucleotide. PMID:35336851
Single-molecule imaging of microRNA-mediated gene silencing in cells. PMID:35301300
The limits of human microRNA annotation have been met. PMID:35236776
Therapeutic Metabolic Reprograming Using microRNAs: From Cancer to HIV Infection. PMID:35205318
Network Approaches to Study Endogenous RNA Competition and Its Impact on Tissue-Specific microRNA Functions. PMID:35204832
Specific microRNAs for Modulation of Autophagy in Spinal Cord Injury. PMID:35204010
Flexible pri-miRNA structures enable tunable production of 5' isomiRs. PMID:35188062
Selection of reference genes for quantitative analysis of microRNA expression in three different types of cancer. PMID:35176014
Disparities in Lung Cancer: miRNA Isoform Characterization in Lung Adenocarcinoma. PMID:35159038
Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop. PMID:35047007
FishmiRNA: An Evolutionarily Supported MicroRNA Annotation and Expression Database for Ray-Finned Fishes. PMID:35020925
The embryonic transcriptome of Parhyale hawaiensis reveals different dynamics of microRNAs and mRNAs during the maternal-zygotic transition. PMID:34996916
miRMut: Annotation of mutations in miRNA genes from human whole-exome or whole-genome sequencing. PMID:34977675
Contributions of microRNAs to Peripheral Insulin Sensitivity. PMID:34882766
MicroRNAs as Indicators into the Causes and Consequences of Whole-Genome Duplication Events. PMID:34865078
MirGeneDB 2.1: toward a complete sampling of all major animal phyla. PMID:34850127
Advances in Non-Coding RNA Sequencing. PMID:34842804
miRGalaxy: Galaxy-Based Framework for Interactive Analysis of microRNA and isomiR Sequencing Data. PMID:34830818
The conserved single-cleavage mechanism of animal DROSHA enzymes. PMID:34824450
Circulating miRNA repertoire as a biomarker of metabolic and reproductive states in rainbow trout. PMID:34781956
Bioinformatic Tools for the Analysis and Prediction of ncRNA Interactions. PMID:34768830
Cestodes in the genomic era. PMID:34665308
miR-1 sustains muscle physiology by controlling V-ATPase complex assembly. PMID:34652942
Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase. PMID:34649994
Single-cell Transcriptomes Reveal Characteristics of MicroRNAs in Gene Expression Noise Reduction. PMID:34606979
miRNATissueAtlas2: an update to the human miRNA tissue atlas. PMID:34570238
GH Overexpression Alters Spermatic Cells MicroRNAome Profile in Transgenic Zebrafish. PMID:34567067
PlasmiR: A Manual Collection of Circulating microRNAs of Prognostic and Diagnostic Value. PMID:34359584
Isolation and Analysis of MicroRNAs from Extracellular Vesicles of the Parasitic Model Nematodes Nippostrongylus brasiliensis and Trichuris muris. PMID:34313996
Secretory microRNA Profiles of Third- and Fourth-Stage Dirofilaria immitis Larvae with Different Macrocyclic Lactone Susceptibility: In Search of Biomarkers for Early Detection of Infection. PMID:34206439
Global mRNA and miRNA Analysis Reveal Key Processes in the Initial Response to Infection with WSSV in the Pacific Whiteleg Shrimp. PMID:34199268
Key Macrophage Responses to Infection With Mycobacterium tuberculosis Are Co-Regulated by microRNAs and DNA Methylation. PMID:34140955
The RNA Atlas expands the catalog of human non-coding RNAs. PMID:34140680
Interrelationship between miRNA and splicing factors in pancreatic ductal adenocarcinoma. PMID:34057028
Evolution after Whole-Genome Duplication: Teleost MicroRNAs. PMID:33871629
In Silico Analysis of Micro-RNA Sequencing Data. PMID:33835446
Digging into bivalve miRNAomes: between conservation and innovation. PMID:33813895
Tumor IsomiR Encyclopedia (TIE): a pancancer database of miRNA isoforms. PMID:33729437
miR-21: a non-specific biomarker of all maladies. PMID:33712063
Sperm fate is promoted by the mir-44 microRNA family in the Caenorhabditis elegans hermaphrodite germline. PMID:33683352
miRNAture-Computational Detection of microRNA Candidates. PMID:33673400
A comparative analysis of heart microRNAs in vertebrates brings novel insights into the evolution of genetic regulatory networks. PMID:33663371
Horseshoe crab genomes reveal the evolution of genes and microRNAs after three rounds of whole genome duplication. PMID:33469163
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes. PMID:33406242
Bulges control pri-miRNA processing in a position and strand-dependent manner. PMID:33382955
Validation of human microRNA target pathways enables evaluation of target prediction tools. PMID:33305319
CoolMPS: evaluation of antibody labeling based massively parallel non-coding RNA sequencing. PMID:33290507
Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development. PMID:33242410
Two MicroRNAs Are Sufficient for Embryonic Patterning in C. elegans. PMID:33125867
Genome of the four-finger threadfin Eleutheronema tetradactylum (Perciforms: Polynemidae). PMID:33076831
Pan-cancer analysis of somatic mutations in miRNA genes. PMID:33038763
Human disease-associated single nucleotide polymorphism changes the orientation of DROSHA on pri-mir-146a. PMID:32994184
Millipede genomes reveal unique adaptations during myriapod evolution. PMID:32991578
Computational Methods and Software Tools for Functional Analysis of miRNA Data. PMID:32872205
MicroRNAs and Apoptosis in Colorectal Cancer. PMID:32731413
MicroRNAs: From Mechanism to Organism. PMID:32582699
Extracellular Vesicle-Contained microRNA of C. elegans as a Tool to Decipher the Molecular Basis of Nematode Parasitism. PMID:32523895
mirnaQC: a webserver for comparative quality control of miRNA-seq data. PMID:32484556
MicroRNA-934 is a novel primate-specific small non-coding RNA with neurogenic function during early development. PMID:32459171
MicroRNA Clustering Assists Processing of Suboptimal MicroRNA Hairpins through the Action of the ERH Protein. PMID:32302541
Identification of Differentially Expressed MicroRNAs and Their Potential Target Genes in Adipose Tissue from Pigs with Highly Divergent Backfat Thickness. PMID:32260506
Ago2-Dependent Processing Allows miR-451 to Evade the Global MicroRNA Turnover Elicited during Erythropoiesis. PMID:32191872
BioSeqZip: a collapser of NGS redundant reads for the optimization of sequence analysis. PMID:31999333
Small RNAs in parasitic nematodes - forms and functions. PMID:31843030 - http://dx.doi.org/10.1101/258749
- http://dx.doi.org/10.1093/nar/gkz885
- http://dx.doi.org/10.1146/annurev-genet-120213-092023
Tags:
Tags
More detailed information about this field from each metasource.
evolution
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
micro rna
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
pre-mirna (pre-microrna)
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
sequence annotation
metasource: Fairsharing.org
version: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
functional, regulatory and non-coding rna
metasource: bio.tools
version: extracted_at: 2022-11-04T11:35:33.563677
Tags
More detailed information about this field from each metasource.
evolution
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
micro rna
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
pre-mirna (pre-microrna)
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
sequence annotation
metasource: Fairsharing.orgversion: FAIRsharing.org: MirGeneDB; MirGeneDB.org; DOI: https://doi.org/10.25504/FAIRsharing.QXSgvF; Last edited: Dec. 12, 2020, 8:14 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
functional, regulatory and non-coding rna
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:35:33.563677
evolution micro rna pre-mirna (pre-microrna) sequence annotation functional, regulatory and non-coding rna
Need help integrating and/or managing biomedical data?