3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk.
PMID:35773720
The genes controlling normal function of citrate and spermine secretion are lost in aggressive prostate cancer and prostate model systems.
PMID:35707723
Heterogeneity of enhancers embodies shared and representative functional groups underlying developmental and cell type-specific gene regulation.
PMID:35680026
Somatic point mutations are enriched in non-coding RNAs with possible regulatory function in breast cancer.
PMID:35672401
The Ramp Atlas: facilitating tissue and cell-specific ramp sequence analyses through an intuitive web interface.
PMID:35664804
Neuronal Cells Display Distinct Stability Controls of Alternative Polyadenylation mRNA Isoforms, Long Non-Coding RNAs, and Mitochondrial RNAs.
PMID:35664307
Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer.
PMID:35562597
Asymmetric Predictive Relationships Across Histone Modifications.
PMID:35529103
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis.
PMID:35484353
microRNA-27b regulates hepatic lipase enzyme LIPC and reduces triglyceride degradation during hepatitis C virus infection.
PMID:35483451
Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data.
PMID:35473573
DNA methylation profile of liver tissue in end-stage cholestatic liver disease.
PMID:35473391
Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene.
PMID:35447887
Sincast: a computational framework to predict cell identities in single-cell transcriptomes using bulk atlases as references.
PMID:35362513
Transcriptional atlas analysis from multiple tissues reveals the expression specificity patterns in beef cattle.
PMID:35351103
Improving reusability along the data life cycle: a regulatory circuits case study.
PMID:35346379
Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression.
PMID:35317119
Sequencing of individual barcoded cDNAs using Pacific Biosciences and Oxford Nanopore Technologies reveals platform-specific error patterns.
PMID:35301264
Simple method for cutoff point identification in descriptive high-throughput biological studies.
PMID:35287573
Immunostimulatory Cancer-Associated Fibroblast Subpopulations Can Predict Immunotherapy Response in Head and Neck Cancer.
PMID:35262677
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue.
PMID:35256815
Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis.
PMID:35219383
Prioritization of putatively detrimental variants in euploid miscarriages.
PMID:35132093
Mouse genomic and cellular annotations.
PMID:35124726
Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive acute myeloid leukemia.
PMID:35121960
Characterization of the COPD alveolar niche using single-cell RNA sequencing.
PMID:35078977
Distribution of alternative untranslated regions within the mRNA of the CELF1 splicing factor affects its expression.
PMID:34996980
Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression.
PMID:34978167
Genomic environments scale the activities of diverse core promoters.
PMID:34961747
Large-Scale Tissue Microarray Evaluation Corroborates High Specificity of High-Level Arginase-1 Immunostaining for Hepatocellular Carcinoma.
PMID:34943588
Multiplexed activation in mammalian cells using a split-intein CRISPR/Cas12a based synthetic transcription factor.
PMID:34908140
CoRE-ATAC: A deep learning model for the functional classification of regulatory elements from single cell and bulk ATAC-seq data.
PMID:34898596
Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas.
PMID:34889867
Natural SINEUP RNAs in Autism Spectrum Disorders: RAB11B-AS1 Dysregulation in a Neuronal CHD8 Suppression Model Leads to RAB11B Protein Increase.
PMID:34880900
Mitochondrial Uncoupling Proteins (UCPs) as Key Modulators of ROS Homeostasis: A Crosstalk between Diabesity and Male Infertility?
PMID:34829617
Integrative Omics Analysis Unravels Microvascular Inflammation-Related Pathways in Kidney Allograft Biopsies.
PMID:34795664
Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency.
PMID:34731163
OncoDB: an interactive online database for analysis of gene expression and viral infection in cancer.
PMID:34718715
Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases.
PMID:34680427
Tree-Based Co-Clustering Identifies Chromatin Accessibility Patterns Associated With Hematopoietic Lineage Structure.
PMID:34659332
scMRMA: single cell multiresolution marker-based annotation.
PMID:34648021
Dichotomy in the Impact of Elevated Maternal Glucose Levels on Neonatal Epigenome.
PMID:34633450
Association Between Posttraumatic Stress Disorder and Epigenetic Age Acceleration in a Sample of Twins.
PMID:34629427
Eosinophil extracellular traps drive asthma progression through neuro-immune signals.
PMID:34616019
Krueppel-Like Factor 4 Expression in Phagocytes Regulates Early Inflammatory Response and Disease Severity in Pneumococcal Pneumonia.
PMID:34589087
Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9.
PMID:34588447
Transcription factors Krüppel-like factor 4 and paired box 5 regulate the expression of the Grainyhead-like genes.
PMID:34570823
Leveraging the Cell Ontology to classify unseen cell types.
PMID:34548483
DDX3X and DDX3Y are redundant in protein synthesis.
PMID:34535544
A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation.
PMID:34529725
Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound.
PMID:34482353
TANC1 methylation as a novel biomarker for the diagnosis of patients with anti-tuberculosis drug-induced liver injury.
PMID:34465797
Introducing Thioredoxin-Related Transmembrane Proteins: Emerging Roles of Human TMX and Clinical Implications.
PMID:34465218
Seeing the forest through the trees: prioritising potentially functional interactions from Hi-C.
PMID:34454581
Transcriptional Regulation of RUNX1: An Informatics Analysis.
PMID:34440349
TERA-Seq: true end-to-end sequencing of native RNA molecules for transcriptome characterization.
PMID:34428294
ZSWIM7 Is Associated With Human Female Meiosis and Familial Primary Ovarian Insufficiency.
PMID:34402903
Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brain.
PMID:34400477
Susceptibility loci and polygenic architecture highlight population specific and common genetic features in inguinal hernias: genetics in inguinal hernias.
PMID:34392144
Pattern of placental alkaline phosphatase (PLAP) expression in human tumors: a tissue microarray study on 12,381 tumors.
PMID:34363325
Dynamic chromatin regulatory landscape of human CAR T cell exhaustion.
PMID:34285077
Telomere-to-telomere assembly of a fish Y chromosome reveals the origin of a young sex chromosome pair.
PMID:34253240
Description of a CSF-Enriched miRNA Panel for the Study of Neurological Diseases.
PMID:34206241
Epigenetic and Transcriptional Control of the Opioid Prodynorphine Gene: In-Depth Analysis in the Human Brain.
PMID:34200173
Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome.
PMID:34187812
Topological Analysis of Regulatory Networks Reveals Functionally Key Genes and miRNAs Involved in the Differentiation of Mesenchymal Stem Cells.
PMID:34179189
Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells.
PMID:34168133
Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study.
PMID:34151794
An AIB1 Isoform Alters Enhancer Access and Enables Progression of Early-Stage Triple-Negative Breast Cancer.
PMID:34135000
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
PMID:34127860
Similarities and Differences in Gene Expression Networks Between the Breast Cancer Cell Line Michigan Cancer Foundation-7 and Invasive Human Breast Cancer Tissues.
PMID:34056582
Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis.
PMID:34021236
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration.
PMID:34012113
Genome-wide analysis of primary microRNA expression using H3K36me3 ChIP-seq data.
PMID:33995896
Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression.
PMID:33986751
Landscape of allele-specific transcription factor binding in the human genome.
PMID:33980847
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney.
PMID:33958779
The phenotypic spectrum associated with OTX2 mutations in humans.
PMID:33950863
Learning a genome-wide score of human-mouse conservation at the functional genomics level.
PMID:33941776
GAPGOM-an R package for gene annotation prediction using GO Metrics.
PMID:33931103
Mesothelin Expression in Human Tumors: A Tissue Microarray Study on 12,679 Tumors.
PMID:33917081
A 127 kb truncating deletion of PGRMC1 is a novel cause of X-linked isolated paediatric cataract.
PMID:33867527
DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic acid intake.
PMID:33784941
A two-stream convolutional neural network for microRNA transcription start site feature integration and identification.
PMID:33707582
Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning.
PMID:33686085
LAMA: automated image analysis for the developmental phenotyping of mouse embryos.
PMID:33574040
A 44-kb deleted-type copy number variation is associated with decreasing complement component activity and calf mortality in Japanese Black cattle.
PMID:33549039
H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions.
PMID:33514712
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain.
PMID:33469025
Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis.
PMID:33320851
A flexible computational pipeline for research analyses of unsolved clinical exome cases.
PMID:33303739
Complex genetic dependencies among growth and neurological phenotypes in healthy children: Towards deciphering developmental mechanisms.
PMID:33270668
Linkage analysis identifies an isolated strabismus locus at 14q12 overlapping with FOXG1 syndrome region.
PMID:33257509
DIANA-miRGen v4: indexing promoters and regulators for more than 1500 microRNAs.
PMID:33245765
Accessing NCBI data using the NCBI Sequence Viewer and Genome Data Viewer (GDV).
PMID:33239395
Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation.
PMID:33238146
ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting.
PMID:33154469
The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer.
PMID:33148262
Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene.
PMID:33148170
The Fuchs corneal dystrophy-associated CTG repeat expansion in the TCF4 gene affects transcription from its alternative promoters.
PMID:33116252
Single-Cell Profiling of AKI in a Murine Model Reveals Novel Transcriptional Signatures, Profibrotic Phenotype, and Epithelial-to-Stromal Crosstalk.
PMID:33115917
Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2.
PMID:33112891
Expression of Calcification and Extracellular Matrix Genes in the Cardiovascular System of the Healthy Domestic Sheep (Ovis aries).
PMID:33101359
Distinctive regulatory architectures of germline-active and somatic genes in C. elegans.
PMID:33093068
Molecular Insights Into Regulatory T-Cell Adaptation to Self, Environment, and Host Tissues: Plasticity or Loss of Function in Autoimmune Disease.
PMID:33072063
Nonmuscle myosin-2 contractility-dependent actin turnover limits the length of epithelial microvilli.
PMID:33026933
Genome-Wide Association Analysis of Neonatal White Matter Microstructure.
PMID:33009551
Stable gene expression for normalisation and single-sample scoring.
PMID:32997146
Integrated regulatory models for inference of subtype-specific susceptibilities in glioblastoma.
PMID:32974985
Comprehensive genomic analysis reveals dynamic evolution of endogenous retroviruses that code for retroviral-like protein domains.
PMID:32963593
Sources of variation in cell-type RNA-Seq profiles.
PMID:32956417
Evaluating the informativeness of deep learning annotations for human complex diseases.
PMID:32943643
Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis.
PMID:32867693
Cis and trans effects differentially contribute to the evolution of promoters and enhancers.
PMID:32819422
SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells.
PMID:32770939
Predictive features of gene expression variation reveal mechanistic link with differential expression.
PMID:32767663
The intersectional genetics landscape for humans.
PMID:32761099
Quantitative characterization of tumor cell-free DNA shortening.
PMID:32650715
Early evidence of delayed oligodendrocyte maturation in the mouse model of mucolipidosis type IV.
PMID:32586947
CYP2J2 Molecular Recognition: A New Axis for Therapeutic Design.
PMID:32534953
BICORN: An R package for integrative inference of de novo cis-regulatory modules.
PMID:32409786
Complex Analysis of Retroposed Genes' Contribution to Human Genome, Proteome and Transcriptome.
PMID:32408516
The DNA methylation landscape of human cancer organoids available at the American type culture collection.
PMID:32396494
Treatable traits and therapeutic targets: Goals for systems biology in infectious disease.
PMID:32363252
Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers.
PMID:32298395
Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies.
PMID:32238901
CDK1 dependent phosphorylation of hTERT contributes to cancer progression.
PMID:32214089
Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding.
PMID:32213323
Fibroblast growth factor receptor 1 gene amplification and protein expression in human lung cancer.
PMID:32207251
Epigenetic modulation of AREL1 and increased HLA expression in brains of multiple system atrophy patients.
PMID:32151281
A putative silencer variant in a spontaneous canine model of retinitis pigmentosa.
PMID:32150541
Identification of methylation states of DNA regions for Illumina methylation BeadChip.
PMID:32138668
Long non-coding RNAs in development and disease: conservation to mechanisms.
PMID:32100288
Global analysis of LARP1 translation targets reveals tunable and dynamic features of 5' TOP motifs.
PMID:32094190
Genome-wide characterization of 5-hydoxymethylcytosine in melanoma reveals major differences with nevus.
PMID:32017278
HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion.
PMID:32010621
Transcriptomic and open chromatin atlas of high-resolution anatomical regions in the rhesus macaque brain.
PMID:31980617
Virus-induced transposable element expression up-regulation in human and mouse host cells.
PMID:31964680
Identification and transfer of spatial transcriptomics signatures for cancer diagnosis.
PMID:31931856
Directional association test reveals high-quality putative cancer driver biomarkers including noncoding RNAs.
PMID:31888644
Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation.
PMID:31888456
Topological structure analysis of chromatin interaction networks.
PMID:31881819
Generation of Retinaldehyde for Retinoic Acid Biosynthesis.
PMID:31861321
Enhancers Facilitate the Birth of De Novo Genes and Gene Integration into Regulatory Networks.
PMID:31845961
Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model.
PMID:31831052
PsyMuKB: An Integrative De Novo Variant Knowledge Base for Developmental Disorders.
PMID:31809863
Hepatocyte gene expression and DNA methylation as ancestry-dependent mechanisms in African Americans.
PMID:31798965
Transcriptional control by enhancers and enhancer RNAs.
PMID:31791217
Personalised analytics for rare disease diagnostics.
PMID:31754101
A network-based approach to identify deregulated pathways and drug effects in metabolic syndrome.
PMID:31740673
Pan-cancer RNA-seq data stratifies tumours by some hallmarks of cancer.
PMID:31730267
Characterization of novel primary miRNA transcription units in human cells using Bru-seq nascent RNA sequencing.
PMID:31709421
Whole Genome Sequencing of Familial Non-Medullary Thyroid Cancer Identifies Germline Alterations in MAPK/ERK and PI3K/AKT Signaling Pathways.
PMID:31614935
Experimental and Computational Approaches to Direct Cell Reprogramming: Recent Advancement and Future Challenges.
PMID:31581647
The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells.
PMID:31543760
Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia.
PMID:31535015
Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA.
PMID:31504804
Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits.
PMID:31501319
Whole-Genome Sequencing of Childhood Cancer Survivors Treated with Cranial Radiation Therapy Identifies 5p15.33 Locus for Stroke: A Report from the St. Jude Lifetime Cohort Study.
PMID:31462438
Complex Phenotypes: Mechanisms Underlying Variation in Human Stature.
PMID:31441021
Repression of ferritin light chain translation by human eIF3.
PMID:31414986
Data-driven characterization of molecular phenotypes across heterogeneous sample collections.
PMID:31329928
Discovery of a novel long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth.
PMID:31253147
Identification of Differential Roles of MicroRNA-33a and -33b During Atherosclerosis Progression With Genetically Modified Mice.
PMID:31242815
The immune cell landscape in kidneys of patients with lupus nephritis.
PMID:31209404
ATP6V0d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis.
PMID:31199856
Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging.
PMID:31141695
Impact of Colon-Specific DNA Methylation-Regulated Gene Modules on Colorectal Cancer Patient Survival.
PMID:31083646
Large-scale in-silico identification of a tumor-specific antigen pool for targeted immunotherapy in triple-negative breast cancer.
PMID:31069014
African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations.
PMID:31023338
Selective translational usage of TSS and core promoters revealed by translatome sequencing.
PMID:30987607
Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs.
PMID:30982597
The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.
PMID:30930166
Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells.
PMID:30891426
Cellular response to small molecules that selectively stall protein synthesis by the ribosome.
PMID:30875366
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
PMID:30865883
Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP.
PMID:30837873
Genetic variants differentially associated with rheumatoid arthritis and systemic lupus erythematosus reveal the disease-specific biology.
PMID:30804378
CpG traffic lights are markers of regulatory regions in human genome.
PMID:30709331
Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens.
PMID:30695034
RAEdb: a database of enhancers identified by high-throughput reporter assays.
PMID:30624654
Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases.
PMID:30610612
The Identification and Interpretation of cis-Regulatory Noncoding Mutations in Cancer.
PMID:30577431
Dichotomy in redundant enhancers points to presence of initiators of gene regulation.
PMID:30563465
Assembly of a parts list of the human mitotic cell cycle machinery.
PMID:30452682
Update of the FANTOM web resource: expansion to provide additional transcriptome atlases.
PMID:30407557
The UCSC Genome Browser database: 2019 update.
PMID:30407534
Multivalent activation of GLP-1 and sulfonylurea receptors modulates β-cell second-messenger signaling and insulin secretion.
PMID:30404557
Methylome of human skeletal muscle after acute & chronic resistance exercise training, detraining & retraining.
PMID:30375987
A neural network based model effectively predicts enhancers from clinical ATAC-seq samples.
PMID:30375457
Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection.
PMID:30352847
Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease.
PMID:30343673
Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury.
PMID:30335683
Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women.
PMID:30258192
De novo pattern discovery enables robust assessment of functional consequences of non-coding variants.
PMID:30256891
Genome-wide analysis of DNA methylation in buccal cells: a study of monozygotic twins and mQTLs.
PMID:30253792
HACER: an atlas of human active enhancers to interpret regulatory variants.
PMID:30247654
An evaluation of supervised methods for identifying differentially methylated regions in Illumina methylation arrays.
PMID:30239597
Transcriptional fates of human-specific segmental duplications in brain.
PMID:30228200
IQSEC2-related encephalopathy in males and females: a comparative study including 37 novel patients.
PMID:30206421
A Computational Method for Classifying Different Human Tissues with Quantitatively Tissue-Specific Expressed Genes.
PMID:30205473
Identification of chronological and photoageing-associated microRNAs in human skin.
PMID:30154427
Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants.
PMID:30139769
Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation.
PMID:30139328
Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli.
PMID:30089658
Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma.
PMID:30076183
Familial Cancer Variant Prioritization Pipeline version 2 (FCVPPv2) applied to a papillary thyroid cancer family.
PMID:30072699
Transcriptional signature primes human oral mucosa for rapid wound healing.
PMID:30045979
The STK35 locus contributes to normal gametogenesis and encodes a lncRNA responsive to oxidative stress.
PMID:29970477
A fine-mapping study of central obesity loci incorporating functional annotation and imputation.
PMID:29967334
CpG island composition differences are a source of gene expression noise indicative of promoter responsiveness.
PMID:29945659
Unsupervised clustering and epigenetic classification of single cells.
PMID:29925875
Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations.
PMID:29895819
Regulatory variants: from detection to predicting impact.
PMID:29893792
Computational approaches for predicting key transcription factors in targeted cell reprogramming (Review).
PMID:29845286
GIANT 2.0: genome-scale integrated analysis of gene networks in tissues.
PMID:29800226
Towards a map of cis-regulatory sequences in the human genome.
PMID:29733395
A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics.
PMID:29727690
Palladin Is a Neuron-Specific Translational Target of mTOR Signaling That Regulates Axon Morphogenesis.
PMID:29712777
A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samples.
PMID:29686738
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.
PMID:29636455
Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data.
PMID:29618048
Peripubertal serum dioxin concentrations and subsequent sperm methylome profiles of young Russian adults.
PMID:29550351
Quantifying tumor-infiltrating immune cells from transcriptomics data.
PMID:29541787
Effects of Cadmium Exposure on DNA Methylation at Imprinting Control Regions and Genome-Wide in Mothers and Newborn Children.
PMID:29529597
Characterization of the human RFX transcription factor family by regulatory and target gene analysis.
PMID:29510665
Unravelling the molecular basis for regulatory T-cell plasticity and loss of function in disease.
PMID:29497530
Somatic mutagenesis in satellite cells associates with human skeletal muscle aging.
PMID:29476074
Identifying noncoding risk variants using disease-relevant gene regulatory networks.
PMID:29453388
Identification of novel hyper- or hypomethylated CpG sites and genes associated with atherosclerotic plaque using an epigenome-wide association study.
PMID:29436575
GM1 ganglioside-independent intoxication by Cholera toxin.
PMID:29432456
Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries.
PMID:29416042
Region-Specific Methylation Profiling in Acute Myeloid Leukemia.
PMID:29405013
ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.
PMID:29353059
Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function.
PMID:29348663
Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region.
PMID:29348432
GIGGLE: a search engine for large-scale integrated genome analysis.
PMID:29309061
PIVOT: platform for interactive analysis and visualization of transcriptomics data.
PMID:29304726
KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells.
PMID:29296711
Principles and methods of in-silico prioritization of non-coding regulatory variants.
PMID:29288389
Deciphering the Relationship between Obesity and Various Diseases from a Network Perspective.
PMID:29258237
DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism.
PMID:29233090
RetrogeneDB-a database of plant and animal retrocopies.
PMID:29220443
Differential Expression of Sox11 and Bdnf mRNA Isoforms in the Injured and Regenerating Nervous Systems.
PMID:29209164
Choice of surrogate tissue influences neonatal EWAS findings.
PMID:29202839
RATA: A method for high-throughput identification of RNA bound transcription factors.
PMID:29201933
Long Non-Coding RNAs in Metabolic Organs and Energy Homeostasis.
PMID:29189723
Monitoring transcription initiation activities in rat and dog.
PMID:29182598
xCell: digitally portraying the tissue cellular heterogeneity landscape.
PMID:29141660
Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head.
PMID:29118346
The genetics of obstructive sleep apnoea.
PMID:29113020
Deconvolution of Transcriptional Networks in Post-Traumatic Stress Disorder Uncovers Master Regulators Driving Innate Immune System Function.
PMID:29101382
MGA repository: a curated data resource for ChIP-seq and other genome annotated data.
PMID:29069466
DiseaseEnhancer: a resource of human disease-associated enhancer catalog.
PMID:29059320
Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy.
PMID:28974727
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.
PMID:28973462
Linking FANTOM5 CAGE peaks to annotations with CAGEscan.
PMID:28972578
A high resolution atlas of gene expression in the domestic sheep (Ovis aries).
PMID:28915238
Systematic analysis of transcription start sites in avian development.
PMID:28873399
RefEx, a reference gene expression dataset as a web tool for the functional analysis of genes.
PMID:28850115
The FANTOM5 collection, a data series underpinning mammalian transcriptome atlases in diverse cell types.
PMID:28850107
FANTOM5 CAGE profiles of human and mouse samples.
PMID:28850106
FANTOM5 CAGE profiles of human and mouse reprocessed for GRCh38 and GRCm38 genome assemblies.
PMID:28850105
An integrated expression atlas of miRNAs and their promoters in human and mouse.
PMID:28829439
Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma.
PMID:28812986
Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer.
PMID:28759043
Novel promoters and coding first exons in DLG2 linked to developmental disorders and intellectual disability.
PMID:28724449
Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells.
PMID:28683826
CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer.
PMID:28679371
Relevance of tissue specific subunit expression in channelopathies.
PMID:28669898
Leucine Differentially Regulates Gene-Specific Translation in Mouse Skeletal Muscle.
PMID:28615380
Hierarchical probabilistic models for multiple gene/variant associations based on next-generation sequencing data.
PMID:28575251
Comprehensive evaluation of disease- and trait-specific enrichment for eight functional elements among GWAS-identified variants.
PMID:28567521
Identification of active miRNA promoters from nuclear run-on RNA sequencing.
PMID:28460090
VEXOR: an integrative environment for prioritization of functional variants in fine-mapping analysis.
PMID:28453673
DNA methylation: an epigenetic mark of cellular memory.
PMID:28450738
De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14+ monocytes and in adipose tissue.
PMID:28389524
Novel RNA biomarkers of prostate cancer revealed by RNA-seq analysis of formalin-fixed samples obtained from Russian patients.
PMID:28380430
Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition.
PMID:28336213
Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy.
PMID:28190459
Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder.
PMID:28153336
Application of hairless mouse strain to bioluminescence imaging of Arc expression in mouse brain.
PMID:28114886
Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci.
PMID:28108556
On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase.
PMID:28025337
The epigenetic landscape of renal cancer.
PMID:27890923
Patterns of ribosomal protein expression specify normal and malignant human cells.
PMID:27884178
Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution.
PMID:27803022
Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals.
PMID:27794045
Computational methods for direct cell conversion.
PMID:27736295
Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling.
PMID:27717381
NDST1 Preferred Promoter Confirmation and Identification of Corresponding Transcriptional Inhibitors as Substrate Reduction Agents for Multiple Mucopolysaccharidosis Disorders.
PMID:27657498
The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.
PMID:27578796
metagene Profiles Analyses Reveal Regulatory Element's Factor-Specific Recruitment Patterns.
PMID:27538250
RNA damage in biological conflicts and the diversity of responding RNA repair systems.
PMID:27536007
Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos.
PMID:27412763
FANTOM5 transcriptome catalog of cellular states based on Semantic MediaWiki.
PMID:27402679
Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells.
PMID:27397025
The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability.
PMID:27377652
Precision Modulation of Neurodegenerative Disease-Related Gene Expression in Human iPSC-Derived Neurons.
PMID:27341390
CAGEd-oPOSSUM: motif enrichment analysis from CAGE-derived TSSs.
PMID:27334471
Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.
PMID:27321945
SCOUP: a probabilistic model based on the Ornstein-Uhlenbeck process to analyze single-cell expression data during differentiation.
PMID:27277014
Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.
PMID:27197205
Parallel computation of genome-scale RNA secondary structure to detect structural constraints on human genome.
PMID:27153986
Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues.
PMID:27003935
Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.
PMID:26965516
Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans.
PMID:26805783
Ensembl 2016.
PMID:26687719
A novel long non-coding RNA in the rheumatoid arthritis risk locus TRAF1-C5 influences C5 mRNA levels.
PMID:26673966
Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences.
PMID:26673039
Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line.
PMID:26635867
COBRA-Seq: Sensitive and Quantitative Methylome Profiling.
PMID:26512698
Impaired atrial natriuretic peptide-mediated lipolysis in obesity.
PMID:26499437
Public data and open source tools for multi-assay genomic investigation of disease.
PMID:26463000
Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution.
PMID:26313521
Whole-genome sequencing identifies a novel ABCB7 gene mutation for X-linked congenital cerebellar ataxia in a large family of Mongolian ancestry.
PMID:26242992
The BioMart community portal: an innovative alternative to large, centralized data repositories.
PMID:25897122