Type 1 Diabetes Database
Names
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Type 1 Diabetes Database
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
T1DBase
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
t1dbase
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
Names
More detailed information about this field from each metasource.
Type 1 Diabetes Database
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
T1DBase
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
t1dbase
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
Names
More detailed information about this field from each metasource.
Type 1 Diabetes Database
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
T1DBase
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
t1dbase
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
This source may no longer be available. No known URL could be resolved successfully.
T1DBase focuses on two research areas in type 1 diabetes (T1D): the genetics of T1D susceptibility and beta cell biology.
Description
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T1DBase focuses on two research areas in type 1 diabetes (T1D): the genetics of T1D susceptibility and beta cell biology.
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Database for type 1 diabetes (T1D). It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. New data sets include curated summary data from four genome-wide association studies relevant to T1D, HaemAtlas-a data set and tool to query gene expression levels in haematopoietic cells and a manually curated table of human T1D susceptibility loci.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
Webpage:
http://t1dbase.org/Webpage
More detailed information about this field from each metasource.
http://t1dbase.org/
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://www.t1dbase.org
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
Licence:
Name: Open Data Commons (ODC) Public Domain Dedication and Licence (PDDL) 1.0Licence name
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Open Data Commons (ODC) Public Domain Dedication and Licence (PDDL) 1.0
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Licence URL
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http://opendatacommons.org/licenses/pddl/1.0/
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
T1DBase: integration and presentation of complex data for type 1 diabetes research
PMID: 17169983
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
PMID: 20937630
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
T1DBase, a community web-based resource for type 1 diabetes research
PMID: 15608258
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Publications
More detailed information about this field from each metasource.
T1DBase: integration and presentation of complex data for type 1 diabetes research
PMID: 17169983
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
PMID: 20937630
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
T1DBase, a community web-based resource for type 1 diabetes research
PMID: 15608258
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
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T1DBase: integration and presentation of complex data for type 1 diabetes research
PubMed citations: 39.
39 articles citing: T1DBase: integration and presentation of complex data for type 1 diabetes research
Risk variants disrupting enhancers of TH1 and TREG cells in type 1 diabetes. PMID:30910956
Network Pharmacology Studies on the Bioactive Compounds and Action Mechanisms of Natural Products for the Treatment of Diabetes Mellitus: A Review. PMID:28280467
TarNet: An Evidence-Based Database for Natural Medicine Research. PMID:27337171
Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice. PMID:26438525
Type 1 Diabetes Prone NOD Mice Have Diminished Cxcr1 mRNA Expression in Polymorphonuclear Neutrophils and CD4+ T Lymphocytes. PMID:26230114
IthaGenes: an interactive database for haemoglobin variations and epidemiology. PMID:25058394
Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity. PMID:23934554
Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes. PMID:23427248
T-HOD: a literature-based candidate gene database for hypertension, obesity and diabetes. PMID:23406793
The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model. PMID:23066155
Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation. PMID:22334700
Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice. PMID:21613616
Meet me halfway: when genomics meets structural bioinformatics. PMID:21350909
Ranking causal variants and associated regions in genome-wide association studies by the support vector machine and random forest. PMID:21317188
Paracrine signalling loops in adult human and mouse pancreatic islets: netrins modulate beta cell apoptosis signalling via dependence receptors. PMID:21212933
Type 2 diabetes genetic association database manually curated for the study design and odds ratio. PMID:21190593
EuroDia: a beta-cell gene expression resource. PMID:20940178
Human protein reference database and human proteinpedia as discovery resources for molecular biotechnology. PMID:20927658
Glucose-induced ERM protein activation and translocation regulates insulin secretion. PMID:20739507
Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene. PMID:20363978
Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes. PMID:20350969
Predicting Type 1 Diabetes Candidate Genes using Human Protein-Protein Interaction Networks. PMID:20148193
Current status and the future for the genetics of type I diabetes. PMID:19956094
Data management: it starts at the bench. PMID:19915619
Accounting for chance in the calculus of autoimmune disease. PMID:19800177
Detection of molecular paths associated with insulitis and type 1 diabetes in non-obese diabetic mouse. PMID:19798418
Coexpression network based on natural variation in human gene expression reveals gene interactions and functions. PMID:19797678
Genomic convergence of genome-wide investigations for complex traits. PMID:19604225
POINeT: protein interactome with sub-network analysis and hub prioritization. PMID:19379523
PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis. PMID:19336676
Detailed transcriptome atlas of the pancreatic beta cell. PMID:19146692
Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A. PMID:19143813
Human Protein Reference Database--2009 update. PMID:18988627
HGVbaseG2P: a central genetic association database. PMID:18948288
GeneSpeed Beta Cell: an online genomics data repository and analysis resource tailored for the islet cell biologist. PMID:18795106
MOPAT: a graph-based method to predict recurrent cis-regulatory modules from known motifs. PMID:18606616
T2D-Db: an integrated platform to study the molecular basis of Type 2 diabetes. PMID:18605991
PADB: published association database. PMID:17877839
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. PMID:17554260 -
T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
PubMed citations: 36.
36 articles citing: T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
Segregation Analysis of Genotyped and Family-Phased, Long Range MHC Classical Class I and Class II Haplotypes in 5 Families With Type 1 Diabetes Proband in the United Arab Emirates. PMID:34276777
Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction. PMID:31920964
Risk variants disrupting enhancers of TH1 and TREG cells in type 1 diabetes. PMID:30910956
UVEOGENE: An SNP database for investigations on genetic factors associated with uveitis and their relationship with other systemic autoimmune diseases. PMID:30614601
Association of serum bilirubin level with lung function decline: a Korean community-based cohort study. PMID:29792214
Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young. PMID:28695611
Persistent coxsackievirus B4 infection induces microRNA dysregulation in human pancreatic cells. PMID:28601984
Can Non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes? PMID:28520980
The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice. PMID:28419211
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. PMID:28241208
Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis. PMID:28078386
ERBB3-rs2292239 as primary type 1 diabetes association locus among non-HLA genes in Chinese. PMID:27331016
Genetic architecture of early pre-inflammatory stage transcription signatures of autoimmune diabetes in the pancreatic lymph nodes of the NOD mouse reveals significant gene enrichment on chromosomes 6 and 7. PMID:26629415
A SNP in the Immunoregulatory Molecule CTLA-4 Controls mRNA Splicing In Vivo but Does Not Alter Diabetes Susceptibility in the NOD Mouse. PMID:26450994
Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes. PMID:26438296
Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity. PMID:26405070
Phenolyzer: phenotype-based prioritization of candidate genes for human diseases. PMID:26192085
Serum Bilirubin and Disease Progression in Mild COPD. PMID:25539285
Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets. PMID:25375650
A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations. PMID:25371288
Hope for GWAS: relevant risk genes uncovered from GWAS statistical noise. PMID:25268625
VSEAMS: a pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes. PMID:25170024
Effects of GWAS-associated genetic variants on lncRNAs within IBD and T1D candidate loci. PMID:25144376
Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers. PMID:25075402
Statistical testing of shared genetic control for potentially related traits. PMID:24227294
TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability. PMID:23970788
Genetic analysis of type 1 diabetes: embryonic stem cells as new tools to unlock biological mechanisms in type 1 diabetes. PMID:23804257
The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes. PMID:23729657
Fibroblast growth factor receptor like-1 (FGFRL1) interacts with SHP-1 phosphatase at insulin secretory granules and induces beta-cell ERK1/2 protein activation. PMID:23640895
New susceptibility loci associated with kidney disease in type 1 diabetes. PMID:23028342
Type 1 diabetes: primary antigen/peptide/register/trimolecular complex. PMID:22956469
Autologous regulatory T cells for the treatment of type 1 diabetes. PMID:22843491
Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression. PMID:22344559
Effects of non-HLA gene polymorphisms on development of islet autoimmunity and type 1 diabetes in a population with high-risk HLA-DR,DQ genotypes. PMID:22315323
The past, present, and future of genetic associations in type 1 diabetes. PMID:21792535
The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection. PMID:21177655 -
T1DBase, a community web-based resource for type 1 diabetes research
PubMed citations: 27.
27 articles citing: T1DBase, a community web-based resource for type 1 diabetes research
Insights on the Role of Putative Muscle-Derived Factors on Pancreatic Beta Cell Function. PMID:31440170
On building a diabetes centric knowledge base via mining the web. PMID:30961582
Risk variants disrupting enhancers of TH1 and TREG cells in type 1 diabetes. PMID:30910956
OCDD: an obesity and co-morbid disease database. PMID:29201145
The circadian gene Arntl2 on distal mouse chromosome 6 controls thymocyte apoptosis. PMID:27671790
Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity. PMID:23934554
Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes. PMID:23427248
The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model. PMID:23066155
GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity. PMID:22242153
Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice. PMID:21613616
When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases. PMID:21255393
EuroDia: a beta-cell gene expression resource. PMID:20940178
A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cell-specific biomarker. PMID:20379810
Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene. PMID:20363978
The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases. PMID:20157484
Systematic analysis, comparison, and integration of disease based human genetic association data and mouse genetic phenotypic information. PMID:20092628
An adenylate kinase is involved in KATP channel regulation of mouse pancreatic beta cells. PMID:17704905
Online genetic databases informing human genome epidemiology. PMID:17610726
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. PMID:17277778
T1DBase: integration and presentation of complex data for type 1 diabetes research. PMID:17169983
EPConDB: a web resource for gene expression related to pancreatic development, beta-cell function and diabetes. PMID:17071715
Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden. PMID:16960798
Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes. PMID:16626483
Genetic epidemiology of type 1 diabetes. PMID:16542625
Exploring supervised and unsupervised methods to detect topics in biomedical text. PMID:16539745
Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes. PMID:16504056
Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes. PMID:15720714
Tags:
Tags
More detailed information about this field from each metasource.
diabetes mellitus
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
disease
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene
metasource: Fairsharing.org
version: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gwas study
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
gene expression
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
pathology
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
genetics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
experimental design and studies
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:34.606139
Tags
More detailed information about this field from each metasource.
diabetes mellitus
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
disease
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gene
metasource: Fairsharing.orgversion: FAIRsharing.org: T1DBase; Type 1 Diabetes Database; DOI: https://doi.org/10.25504/FAIRsharing.9s300d; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
gwas study
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
gene expression
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
pathology
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
genetics
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
experimental design and studies
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:34.606139
diabetes mellitus disease gene gwas study gene expression pathology genetics experimental design and studies
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