Gene Expression Omnibus
Names
More detailed information about this field from each metasource.
Gene Expression Omnibus
metasource: Fairsharing.org
version: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
GEO
metasource: Fairsharing.org
version: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
GEO - Gene Expression Omnibus
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
NCBI GEO
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
ncbi_geo
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
Names
More detailed information about this field from each metasource.
Gene Expression Omnibus
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
GEO
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
GEO - Gene Expression Omnibus
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
NCBI GEO
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:16.605798
ncbi_geo
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:16.605798
Other names: GEO, GEO - Gene Expression Omnibus, NCBI GEO, ncbi_geo
Names
More detailed information about this field from each metasource.
Gene Expression Omnibus
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
GEO
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
GEO - Gene Expression Omnibus
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
NCBI GEO
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:16.605798
ncbi_geo
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:16.605798
The Gene Expression Omnibus (GEO) is a public repository that archives and freely distributes microarray, next-generation sequencing, and other forms of high-throughput functional genomic data submitted by the scientific community. In addition to data storage, a collection of web-based interfaces and applications are available to help users query and download the studies and gene expression patterns stored in GEO.
Description
More detailed information about this field from each metasource.
The Gene Expression Omnibus (GEO) is a public repository that archives and freely distributes microarray, next-generation sequencing, and other forms of high-throughput functional genomic data submitted by the scientific community. In addition to data storage, a collection of web-based interfaces and applications are available to help users query and download the studies and gene expression patterns stored in GEO.
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
GEO serves as a public repository for a wide range of high-throughput experimental data. These data include single and dual channel microarray-based experiments, measuring the abundance of mRNA, genomic DNA and protein molecules. Data from non-array-based high-throughput functional genomics and proteomics technologies are also archived, including serial analysis of gene expression (SAGE) and protein identification technology. Several tools are provided to assist with the visualization and exploration of GEO data, including hierarchical cluster heat maps and searchable individual gene expression profiles. Suitable GEO records are assembled into biologically and statistically comparable datasets. These datasets are then indexed and loaded into Entrez GEO Profiles and Entrez GEO DataSets, which allows users to query and analyze the data using simple boolean queries, and provides links to other NCBI resources wherever possible (e.g. sequence, publication and genomic mapping). GEO is available on the World Wide Web at http://www.ncbi.nlm.nih.gov/geo/. GEO DataSets may be browsed at http://www.ncbi.nlm.nih.gov/geo/gds/gds_browse.cgi or searched by keywords at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gds . GEO Profiles are searchable at (3) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=geo. All these tools are intralinked and accessible from the GEO home page.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Gene Expression Omnibus: a public functional genomics data repository supporting MIAME-compliant data submissions. Array- and sequence-based data are accepted. Tools are provided to help users query and download experiments and curated gene expression profiles.
metasource: re3data.orgversion: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
Database that stores over 20,000 microarray- and sequence-based functional genomics studies, and continues to handle the majority of direct high-throughput data submissions from the research community. Multiple mechanisms are provided to help users effectively search, browse, download and visualize the data at the level of individual genes or entire studies.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:16.605798
Webpage:
http://www.ncbi.nlm.nih.gov/geo/Webpage
More detailed information about this field from each metasource.
http://www.ncbi.nlm.nih.gov/geo/
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
Licence:
Name: GEO Attribution requiredLicence name
More detailed information about this field from each metasource.
GEO Attribution required
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
Copyrights
metasource: re3data.orgversion: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
ODbL-1.0
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:16.605798
Licence URL
More detailed information about this field from each metasource.
https://www.ncbi.nlm.nih.gov/geo/info/linking.html
metasource: Fairsharing.orgversion: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://www.ncbi.nlm.nih.gov/geo/info/disclaimer.html
metasource: re3data.orgversion: re3data.org: Gene Expression Omnibus; editing status 2021-09-02; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33P44 last accessed: 2022-11-04
Publications:
Publications
More detailed information about this field from each metasource.
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
PMID: 11752295
metasource: Fairsharing.org
version: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
NCBI GEO: archive for functional genomics data sets--update
PMID: 23193258
metasource: Fairsharing.org
version: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
NCBI GEO: archive for functional genomics data sets--10 years on
PMID: 21097893
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
Submission of microarray data to public repositories
PMID: 15340489
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
http://dx.doi.org/10.1093/nar/gks1193
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
PMID: 11752295
metasource: Fairsharing.org
version: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
NCBI GEO: archive for functional genomics data sets--update
PMID: 23193258
metasource: Fairsharing.org
version: FAIRsharing.org: GEO; Gene Expression Omnibus; DOI: https://doi.org/10.25504/FAIRsharing.5hc8vt; Last edited: April 26, 2021, 11:57 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
NCBI GEO: archive for functional genomics data sets--10 years on
PMID: 21097893
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
Submission of microarray data to public repositories
PMID: 15340489
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:16.605798
http://dx.doi.org/10.1093/nar/gks1193
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
PubMed citations: 5825.
5825 articles citing: Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
Cogito: automated and generic comparison of annotated genomic intervals. PMID:35927614
METTL3 preferentially enhances non-m6A translation of epigenetic factors and promotes tumourigenesis. PMID:35927451
Cellular recovery after prolonged warm ischaemia of the whole body. PMID:35922506
Evolutionary Relationships Between Dysregulated Genes in Oral Squamous Cell Carcinoma and Oral Microbiota. PMID:35909962
Cancer-testis antigen KK-LC-1 is a potential biomarker associated with immune cell infiltration in lung adenocarcinoma. PMID:35907786
CC chemokine receptor 7 promotes macrophage recruitment and induces M2-polarization through CC chemokine ligand 19&21 in oral squamous cell carcinoma. PMID:35904690
The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope. PMID:35902632
Overexpression of OAS1 Is Correlated With Poor Prognosis in Pancreatic Cancer. PMID:35898870
Global Profiling of Genes Expressed in the Silk Glands of Philippine-Reared Mulberry Silkworms (Bombyx mori). PMID:35893024
Immunomodulatory Responses of Subcapsular Sinus Floor Lymphatic Endothelial Cells in Tumor-Draining Lymph Nodes. PMID:35892863
Stemness Correlates Inversely with MHC Class I Expression in Pediatric Small Round Blue Cell Tumors. PMID:35892842
The Protective Effect of Edaravone on TDP-43 Plus Oxidative Stress-Induced Neurotoxicity in Neuronal Cells: Analysis of Its Neuroprotective Mechanisms Using RNA Sequencing. PMID:35890141
Transcriptional Profiling of Leishmania infantum Infected Dendritic Cells: Insights into the Role of Immunometabolism in Host-Parasite Interaction. PMID:35888991
Prenatal Detection of Novel Compound Heterozygous Splice Site Variants of the KIAA0825 Gene in a Fetus with Postaxial Polydactyly Type A. PMID:35886013
High Oxytocin Receptor Expression Linked to Increased Cell Migration and Reduced Survival in Patients with Triple-Negative Breast Cancer. PMID:35884900
Integrated Clinical and Genomic Models to Predict Optimal Cytoreduction in High-Grade Serous Ovarian Cancer. PMID:35884615
Large-Scale Profiling on lncRNAs in Human Platelets: Correlation with Platelet Reactivity. PMID:35883699
Induced Endothelial Cell-Integrated Liver Assembloids Promote Hepatic Maturation and Therapeutic Effect on Cholestatic Liver Fibrosis. PMID:35883684
In silico discovery of blood cell macromolecular associations. PMID:35879676
Identification of Metabolic Syndrome-Related miRNA-mRNA Regulatory Networks and Key Genes Based on Bioinformatics Analysis. PMID:35877019
Getting Started with LINCS Datasets and Tools. PMID:35876555
Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease. PMID:35874275
Unveiling Co-Infection in Cystic Fibrosis Airways: Transcriptomic Analysis of Pseudomonas aeruginosa and Staphylococcus aureus Dual-Species Biofilms. PMID:35873457
The Lack of the TetR-Like Repressor Gene BCG_2177c (Rv2160A) May Help Mycobacteria Overcome Intracellular Redox Stress and Survive Longer Inside Macrophages When Surrounded by a Lipid Environment. PMID:35873160
In silico Identification of Immune Cell-Types and Pathways Involved in Chronic Spontaneous Urticaria. PMID:35872776
EpiVisR: exploratory data analysis and visualization in epigenome-wide association analyses. PMID:35870905
Increased Development of Th1, Th17, and Th1.17 Cells Under T1 Polarizing Conditions in Juvenile Idiopathic Arthritis. PMID:35860254
Un-biased housekeeping gene panel selection for high-validity gene expression analysis. PMID:35853974
An Immunity-Related Gene Model Predicts Prognosis in Cholangiocarcinoma. PMID:35847907
Predicting the Lung Adenocarcinoma and Its Biomarkers by Integrating Gene Expression and DNA Methylation Data. PMID:35846148
Senescent Tumor Cells in the Peritoneal Carcinomatosis Drive Immunosenescence in the Tumor Microenvironment. PMID:35844581
Single-Cell RNA Sequencing Unravels Upregulation of Immune Cell Crosstalk in Relapsed Pediatric Ependymoma. PMID:35844565
Uncovering a Genetic Polymorphism Located in Huntingtin Associated Protein 1 in Modulation of Central Pain Sensitization Signaling Pathways. PMID:35837121
Differential gene screening and bioinformatics analysis of epidermal stem cells and dermal fibroblasts during skin aging. PMID:35835980
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells. PMID:35831270
Multivariate competing endogenous RNA network characterization for cancer microRNA biomarker discovery: a novel bioinformatics model with application to prostate cancer metastasis. PMID:35821682
Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Berberine in the Treatment of Ischaemic Stroke. PMID:35815278
The clinical relevance of unfolded protein response signaling in breast cancer. PMID:35812054
miR-218-5p/RUNX2 Axis Positively Regulates Proliferation and Is Associated with Poor Prognosis in Cervical Cancer. PMID:35805994
DNA methylation fingerprint of hepatocellular carcinoma from tissue and liquid biopsies. PMID:35798798
Vitexin Mitigates Staphylococcus aureus-Induced Mastitis via Regulation of ROS/ER Stress/NF-κB/MAPK Pathway. PMID:35795861
Cytokinin and Its Key Role to Enrich the Plant Nutrients and Growth Under Adverse Conditions-An Update. PMID:35795201
Downregulation of LRRC19 Is Associated with Poor Prognosis in Colorectal Cancer. PMID:35794979
Highly perturbed genes and hub genes associated with type 2 diabetes in different tissues of adult humans: a bioinformatics analytic workflow. PMID:35788821
Integrated Analysis of Immune-Related circRNA-miRNA-mRNA Regulatory Network in Ischemic Stroke. PMID:35785353
Exposure of Keratinocytes to Candida Albicans in the Context of Atopic Milieu Induces Changes in the Surface Glycosylation Pattern of Small Extracellular Vesicles to Enhance Their Propensity to Interact With Inhibitory Siglec Receptors. PMID:35784319
SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates. PMID:35776115
The Bioinformatic Study Uncovers Probable Critical Genes Involved in the Pathophysiology of Biliary Atresia. PMID:35774294
FBXO38 Ubiquitin Ligase Controls Sertoli Cell Maturation. PMID:35769260
Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. PMID:35768464
Farnesoid X receptor protects against cisplatin-induced acute kidney injury by regulating the transcription of ferroptosis-related genes. PMID:35767918
Network-based machine learning approach to predict immunotherapy response in cancer patients. PMID:35764641
Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression. PMID:35763346
Context-aware deconvolution of cell-cell communication with Tensor-cell2cell. PMID:35760817
Transcriptomic Profiling of Plaque Psoriasis and Cutaneous T-Cell Subsets during Treatment with Secukinumab. PMID:35757784
Driving innovation for rare skin cancers: utilizing common tumours and machine learning to predict immune checkpoint inhibitor response. PMID:35755000
Pathway importance by graph convolutional network and Shapley additive explanations in gene expression phenotype of diffuse large B-cell lymphoma. PMID:35749395
Model scenarios for cell cycle re-entry in Alzheimer's disease. PMID:35747391
Circulating miRNAs as Potential Biomarkers for Patient Stratification in Bipolar Disorder: A Combined Review and Data Mining Approach. PMID:35741801
Exploring the Core Genes of Schizophrenia Based on Bioinformatics Analysis. PMID:35741729
Identifying the Potential Roles of PBX4 in Human Cancers Based on Integrative Analysis. PMID:35740947
Murine Falcor/LL35 lncRNA Contributes to Glucose and Lipid Metabolism In Vitro and In Vivo. PMID:35740417
Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development. PMID:35733248
Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence. PMID:35727842
An 8-Gene Signature for Classifying Major Subtypes of Non-Small-Cell Lung Cancer. PMID:35722224
C1QTNF3 is Upregulated During Subcutaneous Adipose Tissue Remodeling and Stimulates Macrophage Chemotaxis and M1-Like Polarization. PMID:35720277
Identification of Differentially Expressed Genes and miRNAs for Ulcerative Colitis Using Bioinformatics Analysis. PMID:35719390
Network Control Models With Personalized Genomics Data for Understanding Tumor Heterogeneity in Cancer. PMID:35712516
Identification of Prognosis-Related Molecular Subgroups and Construction of a Prognostic Prediction Model Using Immune-Related Genes in Pancreatic Cancer. PMID:35712127
Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors. PMID:35711359
Integrated analysis reveals the pivotal interactions between immune cells in the melanoma tumor microenvironment. PMID:35710862
Identification of HOX signatures contributing to oral cancer phenotype. PMID:35710803
SFARI genes and where to find them; modelling Autism Spectrum Disorder specific gene expression dysregulation with RNA-seq data. PMID:35710789
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles. PMID:35710644
Premature Infants Have Normal Maturation of the T Cell Receptor Repertoire at Term. PMID:35707545
Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasets. PMID:35705903
Enhancing the REMBRANDT MRI collection with expert segmentation labels and quantitative radiomic features. PMID:35701399
Host protease activity classifies pneumonia etiology. PMID:35696579
The Olfactory Organ Is a Unique Site for Neutrophils in the Brain. PMID:35693773
Decoding the Mechanism behind the Pathogenesis of the Focal Segmental Glomerulosclerosis. PMID:35693262
SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1. PMID:35688210
Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI). PMID:35687583
Role of Nucleolin in Endometrial Precancerous Hyperplasia and Carcinogenesis: Ex Vivo and In Silico Study. PMID:35682908
The AKT1E17K Allele Promotes Breast Cancer in Mice. PMID:35681625
Chronic Chemogenetic Activation of the Superior Colliculus in Glaucomatous Mice: Local and Retrograde Molecular Signature. PMID:35681479
MicroRNAs and other small RNAs in Aedes aegypti saliva and salivary glands following chikungunya virus infection. PMID:35681077
Identification of biomarkers for immunotherapy response in prostate cancer and potential drugs to alleviate immunosuppression. PMID:35680563
An epigenome-wide view of osteoarthritis in primary tissues. PMID:35679866
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation. PMID:35672452
STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway. PMID:35668064
Identification of Metabolic Pathways Differentially Regulated in Somatic and Zygotic Embryos of Maritime Pine. PMID:35665168
The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection. PMID:35665009
Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons. PMID:35659876
Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus. PMID:35659263
A gene prognostic index from cellular senescence predicting metastasis and radioresistance for prostate cancer. PMID:35658892
Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions. PMID:35658533
The snoGloBe interaction predictor reveals a broad spectrum of C/D snoRNA RNA targets. PMID:35657102
Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma. PMID:35656182
JUN and PDGFRA as Crucial Candidate Genes for Childhood Autism Spectrum Disorder. PMID:35655651
Esrrb Regulates Specific Feed-Forward Loops to Transit From Pluripotency Into Early Stages of Differentiation. PMID:35652095
Persister state-directed transitioning and vulnerability in melanoma. PMID:35650266
Characterisation of a nucleo-adhesome. PMID:35650196
Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review. PMID:35641998
Target and drug predictions for SARS-CoV-2 infection in hepatocellular carcinoma patients. PMID:35639708
Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer's disease revealed by weighted gene co-expression network analysis. PMID:35637434
Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations. PMID:35637371
LIM Homeobox-2 Suppresses Hallmarks of Adult and Pediatric Liver Cancers by Inactivating MAPK/ERK and Wnt/Beta-Catenin Pathways. PMID:35634422
Chronic Exposure to the Food Additive tBHQ Modulates Expression of Genes Related to SARS-CoV-2 and Influenza Viruses. PMID:35629310
miR-486-5p and miR-22-3p Enable Megakaryocytic Differentiation of Hematopoietic Stem and Progenitor Cells without Thrombopoietin. PMID:35628168
The Circadian Clock in the Retinal Pigment Epithelium Controls the Diurnal Rhythm of Phagocytic Activity. PMID:35628111
miRNA Pattern in Hypoxic Microenvironment of Kidney Cancer-Role of PTEN. PMID:35625614
CDC25C is a prognostic biomarker and correlated with mitochondrial homeostasis in pancreatic adenocarcinoma. PMID:35615982
Identification of Differential Genes of DNA Methylation Associated With Alzheimer's Disease Based on Integrated Bioinformatics and Its Diagnostic Significance. PMID:35615586
Exploration of Potential Biomarker Genes and Pathways in Kawasaki Disease: An Integrated in-Silico Approach. PMID:35615376
Identification and validation of aging-related genes in COPD based on bioinformatics analysis. PMID:35609226
The Overexpression of Fibronectin 1 Promotes Cancer Progression and Associated with M2 Macrophages Polarization in Head and Neck Squamous Cell Carcinoma Patients. PMID:35607361
PqsE Expands and Differentially Modulates the RhlR Quorum Sensing Regulon in Pseudomonas aeruginosa. PMID:35604161
NUF2 Is a Potential Immunological and Prognostic Marker for Non-Small-Cell Lung Cancer. PMID:35600043
Dataset of differentially expressed genes in mouse P12 testes in response to the loss of ATRX in Sertoli cells. PMID:35592768
Adaptation of the gut pathobiont Enterococcus faecalis to deoxycholate and taurocholate bile acids. PMID:35590028
The impact of short-term confinement on human innate immunity. PMID:35589846
Interleukin-4 receptor signaling modulates neuronal network activity. PMID:35587822
Identification and validation of an eight-lncRNA signature that predicts prognosis in patients with esophageal squamous cell carcinoma. PMID:35578166
An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. PMID:35577777
Integrated Analysis of Transcriptome Data Revealed AURKA and KIF20A as Critical Genes in Medulloblastoma Progression. PMID:35574421
High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice. PMID:35573198
Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease. PMID:35572351
NMDA Receptor Antagonists Increase the Release of GLP-1 From Gut Endocrine Cells. PMID:35571112
Immunophenotyping of Acute Inflammatory Exacerbations of Lung Injury Driven by Mutant Surfactant Protein-C: A Role for Inflammatory Eosinophils. PMID:35571100
The Phytotoxin Myrigalone A Triggers a Phased Detoxification Programme and Inhibits Lepidium sativum Seed Germination via Multiple Mechanisms including Interference with Auxin Homeostasis. PMID:35563008
Systems-wide analysis revealed shared and unique responses to moderate and acute high temperatures in the green alga Chlamydomonas reinhardtii. PMID:35562408
Assessing the Potential Prognostic and Immunological Role of TK1 in Prostate Cancer. PMID:35559045
Identification of potential prognostic biomarkers for hepatocellular carcinoma. PMID:35557563
Enhancing Data Integration, Interoperability, and Reuse to Address Complex and Emerging Environmental Health Problems. PMID:35549252
Artificial intelligence in cancer target identification and drug discovery. PMID:35538061
Identification of key gene contributing to vitiligo by immune infiltration. PMID:35535201
Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology. PMID:35531351
Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation. PMID:35528975
SigCom LINCS: data and metadata search engine for a million gene expression signatures. PMID:35524556
3'untranslated regions of tumor suppressor genes evolved specific features to favor cancer resistance. PMID:35523946
Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration. PMID:35508452
MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors. PMID:35503250
Construction of a lncRNA-associated competing endogenous RNA regulatory network after traumatic brain injury in mouse. PMID:35501920
Low Level of PALMD Contributes to the Metastasis of Uveal Melanoma. PMID:35494064
RNA-seq profiling of tubulointerstitial tissue reveals a potential therapeutic role of dual anti-phosphatase 1 in glomerulonephritis. PMID:35488446
Fluorescent tracking identifies key migratory dendritic cells in the lymph node after radiotherapy. PMID:35487695
Temporal and sex-dependent gene expression patterns in a renal ischemia-reperfusion injury and recovery pig model. PMID:35484379
An Arabidopsis mutant deficient in phosphatidylinositol-4-phosphate kinases ß1 and ß2 displays altered auxin-related responses in roots. PMID:35484296
EBAG9 controls CD8+ T cell memory formation responding to tumor challenge in mice. PMID:35482418
lncRNA MALAT1 mediates osteogenic differentiation of bone mesenchymal stem cells by sponging miR-129-5p. PMID:35480561
Cancer Progression Gene Expression Profiling Identifies the Urokinase Plasminogen Activator Receptor as a Biomarker of Metastasis in Cutaneous Squamous Cell Carcinoma. PMID:35480116
Icariin: A Potential Molecule for Treatment of Knee Osteoarthritis. PMID:35479319
Human placental proteomics and exon variant studies link AAT/SERPINA1 with spontaneous preterm birth. PMID:35477570
Critical contribution of 3' non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA. PMID:35476978
Alfalfa (Medicago sativa L.) pho2 mutant plants hyperaccumulate phosphate. PMID:35471600
Streptococcus pyogenes Hijacks Host Glutathione for Growth and Innate Immune Evasion. PMID:35467425
Pseudomonas aeruginosa Initiates a Rapid and Specific Transcriptional Response during Surface Attachment. PMID:35467391
Screening of Medications for Idiopathic Membranous Nephropathy Using Glomerular Whole-Genome Sequencing. PMID:35465008
Mitochondria Dysfunction-Mediated Molecular Subtypes and Gene Prognostic Index for Prostate Cancer Patients Undergoing Radical Prostatectomy or Radiotherapy. PMID:35463369
Characterization of transcriptome diversity and in vitro behavior of primary human high-risk breast cells. PMID:35459280
Recognition of a Novel Gene Signature for Human Glioblastoma. PMID:35456975
Transcriptional Profiling and Deriving a Seven-Gene Signature That Discriminates Active and Latent Tuberculosis: An Integrative Bioinformatics Approach. PMID:35456421
Prolonged Cadmium Exposure Alters Migration Dynamics and Increases Heterogeneity of Human Uterine Fibroid Cells-Insights from Time Lapse Analysis. PMID:35453667
Coexpression reveals conserved gene programs that co-vary with cell type across kingdoms. PMID:35451481
Global expression profiling of CD10 + /CD19 + pre-B lymphoblasts from Hispanic B-ALL patients correlates with comparative TARGET database analysis. PMID:35445848
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition. PMID:35444283
3JC48-3 (methyl 4'-methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1'-biphenyl]-3-carboxylate): a novel MYC/MAX dimerization inhibitor reduces prostate cancer growth. PMID:35440696
Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cells. PMID:35440627
An evolutionarily conserved stop codon enrichment at the 5' ends of mammalian piRNAs. PMID:35440552
PELO facilitates PLK1-induced the ubiquitination and degradation of Smad4 and promotes the progression of prostate cancer. PMID:35437307
Genome-wide Identification and Expression Analysis of RcMYB Genes in Rhodiola crenulata. PMID:35432456
The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1. PMID:35428820
Systematic Characterization of the Clinical Relevance of KPNA4 in Pancreatic Ductal Adenocarcinoma. PMID:35425701
Construction of a Joint Prediction Model for the Occurrence of Ischemic Stroke and Acute Myocardial Infarction Based on Bioinformatic Analysis. PMID:35419117
The Arabidopsis F-box protein FBW2 targets AGO1 for degradation to prevent spurious loading of illegitimate small RNA. PMID:35417704
Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue. PMID:35413480
Neural network modeling of differential binding between wild-type and mutant CTCF reveals putative binding preferences for zinc fingers 1-2. PMID:35410161
ENPP2 Promoter Methylation Correlates with Decreased Gene Expression in Breast Cancer: Implementation as a Liquid Biopsy Biomarker. PMID:35409077
ELK3 Controls Gastric Cancer Cell Migration and Invasion by Regulating ECM Remodeling-Related Genes. PMID:35409069
Construction of MicroRNA-mRNA Regulatory Network in the Molecular Mechanisms of Bleomycin-Induced Pulmonary Fibrosis. PMID:35402615
BTG2 as a tumor target for the treatment of luminal A breast cancer. PMID:35401805
Transcriptomic Analysis of Liver Indicates Novel Vaccine to Porcine Reproductive and Respiratory Virus Promotes Homeostasis in T-Cell and Inflammatory Immune Responses Compared to a Commercial Vaccine in Pigs. PMID:35400088
Molecular mechanisms underlying plasticity in a thermally varying environment. PMID:35397190
The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma. PMID:35395492
Predicted mouse interactome and network-based interpretation of differentially expressed genes. PMID:35390003
Predictive biomarkers for survival benefit with ramucirumab in urothelial cancer in the RANGE trial. PMID:35388003
Comparative functional genomics identifies an iron-limited bottleneck in a Saccharomyces cerevisiae strain with a cytosolic-localized isobutanol pathway. PMID:35387233
Purinergic Receptors in the Airways: Potential Therapeutic Targets for Asthma? PMID:35386996
Translational Analysis of Moderate to Severe Asthma GWAS Signals Into Candidate Causal Genes and Their Functional, Tissue-Dependent and Disease-Related Associations. PMID:35386986
Network-based stage-specific drug repurposing for Alzheimer's disease. PMID:35386099
Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells. PMID:35379199
High-resolution Slide-seqV2 spatial transcriptomics enables discovery of disease-specific cell neighborhoods and pathways. PMID:35372810
Immunopeptidomic analyses of colorectal cancers with and without microsatellite instability. PMID:35367648
Computational analyses of mechanism of action (MoA): data, methods and integration. PMID:35360890
A Link Between Mitochondrial Dysfunction and the Immune Microenvironment of Salivary Glands in Primary Sjogren's Syndrome. PMID:35359935
Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia. PMID:35358280
LKB1 acts as a critical brake for the glucagon-mediated fasting response. PMID:35357082
Transcript and blood-microbiome analysis towards a blood diagnostic tool for goats affected by Haemonchus contortus. PMID:35354850
Cardiac pericyte reprogramming by MEK inhibition promotes arteriologenesis and angiogenesis of the ischemic heart. PMID:35349488
Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8. PMID:35343786
Single-Cell Analysis of Refractory Celiac Disease Demonstrates Inter- and Intra-Patient Aberrant Cell Heterogeneity. PMID:35338007
Machine Learning-Based Identification of Colon Cancer Candidate Diagnostics Genes. PMID:35336739
Transcriptomic Stress Response in Streptococcus mutans following Treatment with a Sublethal Concentration of Chlorhexidine Digluconate. PMID:35336136
Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice. PMID:35332188
Tissue-Specific Methylation Biosignatures for Monitoring Diseases: An In Silico Approach. PMID:35328380
Screening the Significant Hub Genes by Comparing Tumor Cells, Normoxic and Hypoxic Glioblastoma Stem-like Cell Lines Using Co-Expression Analysis in Glioblastoma. PMID:35328072
Identification of the TF-miRNA-mRNA co-regulatory networks involved in sepsis. PMID:35322335
A flexible model-free prediction-based framework for feature ranking. PMID:35321091
Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa-Porthos axis in Drosophila. PMID:35319107
Overexpression of CISD1 Predicts Worse Survival in Hepatocarcinoma Patients. PMID:35313629
Nucleoporin107 mediates female sexual differentiation via Dsx. PMID:35311642
Target-Dependent Coordinated Biogenesis of Secondary MicroRNAs by miR-146a Balances Macrophage Activation Processes. PMID:35311564
Blood SSR1: A Possible Biomarker for Early Prediction of Parkinson's Disease. PMID:35310885
Expression of AtWRI1 and AtDGAT1 during soybean embryo development influences oil and carbohydrate metabolism. PMID:35306726
Establishment of a Combined Diagnostic Model of Abdominal Aortic Aneurysm with Random Forest and Artificial Neural Network. PMID:35299890
Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma. PMID:35296644
Experimental evolution links post-transcriptional regulation to Leishmania fitness gain. PMID:35294501
Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets dysregulated macrophage processes in inflammatory bowel disease. PMID:35288651
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis. PMID:35288533
A mobile restriction-modification system provides phage defence and resolves an epigenetic conflict with an antagonistic endonuclease. PMID:35286398
The Key Genes Underlying Pathophysiology Correlation Between the Acute Myocardial Infarction and COVID-19. PMID:35282650
Exploring the Communal Pathogenesis, Ferroptosis Mechanism, and Potential Therapeutic Targets of Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy via a Microarray Data Analysis. PMID:35282347
Identification of a seven-gene prognostic signature using the gene expression profile of osteosarcoma. PMID:35282067
Restoration of Default Blood Monocyte-Derived Macrophage Polarization With Adalimumab But Not Etanercept in Rheumatoid Arthritis. PMID:35281074
Energy Metabolism-Related Gene Prognostic Index Predicts Biochemical Recurrence for Patients With Prostate Cancer Undergoing Radical Prostatectomy. PMID:35280985
High-Calcium Microenvironment during the Development of Kidney Calculi Can Promote Phenotypic Transformation of NRK-52E Cells by Inhibiting the Expression of Stromal Interaction Molecule-1. PMID:35274024
Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in Isl1 Conditional Mutants. PMID:35273083
Human Sex Matters: Y-Linked Lysine Demethylase 5D Drives Accelerated Male Craniofacial Osteogenic Differentiation. PMID:35269444
Diurnal and circadian rhythmicity of the human blood transcriptome overlaps with organ- and tissue-specific expression of a non-human primate. PMID:35264172
Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis. PMID:35262173
The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain. PMID:35260802
Regulation of chromatin accessibility by hypoxia and HIF. PMID:35258521
RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. PMID:35253846
A network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease. PMID:35252807
Genome-Wide Methylation Profiling in the Thalamus of Scrapie Sheep. PMID:35252421
An Integrated Analysis of the Identified PRPF19 as an Onco-immunological Biomarker Encompassing the Tumor Microenvironment, Disease Progression, and Prognoses in Hepatocellular Carcinoma. PMID:35252202
Chromatin Changes in Phytochrome Interacting Factor-Regulated Genes Parallel Their Rapid Transcriptional Response to Light. PMID:35251080
High RAD51 gene expression is associated with aggressive biology and with poor survival in breast cancer. PMID:35249172
In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies. PMID:35246475
Predicting molecular initiating events using chemical target annotations and gene expression. PMID:35246223
Identification of Crucial Genes and Key Functions in Type 2 Diabetic Hearts by Bioinformatic Analysis. PMID:35242109
Identification of novel therapeutic targets for Fuchs' endothelial corneal dystrophy based on gene bioinformatics analysis. PMID:35239706
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease. PMID:35238641
i6mA-Vote: Cross-Species Identification of DNA N6-Methyladenine Sites in Plant Genomes Based on Ensemble Learning With Voting. PMID:35237293
PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production. PMID:35236967
CASowary: CRISPR-Cas13 guide RNA predictor for transcript depletion. PMID:35236300
Summarizing internal dynamics boosts differential analysis and functional interpretation of super enhancers. PMID:35234924
CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis. PMID:35234914
Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology. PMID:35229638
PUCHI represses early meristem formation in developing lateral roots of Arabidopsis thaliana. PMID:35224628
A Ferroptosis-Related Gene Prognostic Index Associated With Biochemical Recurrence and Radiation Resistance for Patients With Prostate Cancer Undergoing Radical Radiotherapy. PMID:35223835
Identification of NUTF2 as a Candidate Diagnostic and Prognostic Biomarker Associated with Immune Infiltration in Head and Neck Squamous Cell Carcinoma. PMID:35221694
Network meta-analysis of transcriptome expression changes in different manifestations of dengue virus infection. PMID:35220956
An in-frame deletion mutation in the degron tail of auxin coreceptor IAA2 confers resistance to the herbicide 2,4-D in Sisymbrium orientale. PMID:35217601
Identification of Nifurtimox and Chrysin as Anti-Influenza Virus Agents by Clinical Transcriptome Signature Reversion. PMID:35216485
Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells. PMID:35215969
Analysing miRNA-Target Gene Networks in Inflammatory Bowel Disease and Other Complex Diseases Using Transcriptomic Data. PMID:35205414
DRPPM-EASY: A Web-Based Framework for Integrative Analysis of Multi-Omics Cancer Datasets. PMID:35205126
Tissular Genomic Responses to Oral FB1 Exposure in Pigs. PMID:35202111
Hsa-miR-183-5p Modulates Cell Adhesion by Repression of ITGB1 Expression in Prostate Cancer. PMID:35202085
Identification of Potential Cytokinin Responsive Key Genes in Rice Treated With Trans-Zeatin Through Systems Biology Approach. PMID:35198001
PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer. PMID:35197445
Th1 cells are dispensable for primary clearance of Chlamydia from the female reproductive tract of mice. PMID:35196366
THRSP identified as a potential hepatocellular carcinoma marker by integrated bioinformatics analysis and experimental validation. PMID:35196258
tensorGSEA: Detecting Differential Pathways in Type 2 Diabetes via Tensor-Based Data Reconstruction. PMID:35195883
SEAseq: a portable and cloud-based chromatin occupancy analysis suite. PMID:35193506
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma. PMID:35186752
Genotypic Variation of Nitrogen Use Efficiency and Amino Acid Metabolism in Barley. PMID:35185958
Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies. PMID:35185888
Identification of Transcriptional Pattern Related to Immune Cell Infiltration With Gene Co-Expression Network in Papillary Thyroid Cancer. PMID:35185791
FET fusion oncoproteins interact with BRD4 and SWI/SNF chromatin remodelling complex subtypes in sarcoma. PMID:35182012
Inferring Causation in Yeast Gene Association Networks With Kernel Logistic Regression. PMID:35173404
Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. PMID:35168652
Aureochromes maintain polyunsaturated fatty acid content in Nannochloropsis oceanica. PMID:35166829
Is Cadmium Toxicity Tissue-Specific? Toxicogenomics Studies Reveal Common and Specific Pathways in Pulmonary, Hepatic, and Neuronal Cell Models. PMID:35163690
Spheroid Culture Differentially Affects Cancer Cell Sensitivity to Drugs in Melanoma and RCC Models. PMID:35163092
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I. PMID:35162981
Aging Activates the Immune System and Alters the Regenerative Capacity in the Zebrafish Heart. PMID:35159152
gpuZoo: Cost-effective estimation of gene regulatory networks using the Graphics Processing Unit. PMID:35156023
In silico bioinformatics analysis for identification of differentially expressed genes and therapeutic drug molecules in Glucocorticoid-resistant Multiple myeloma. PMID:35150335
Osmotic stress induces long-term biofilm survival in Liberibacter crescens. PMID:35148684
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris. PMID:35142597
USP25 Expression in Peripheral Blood Mononuclear Cells Is Associated With Bone Mineral Density in Women. PMID:35141233
A framework to predict the applicability of Oncotype DX, MammaPrint, and E2F4 gene signatures for improving breast cancer prognostic prediction. PMID:35140308
Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response. PMID:35140216
Age-related long-term response in rat thyroid tissue and plasma after internal low dose exposure to 131I. PMID:35136135
Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection. PMID:35131898
Identification of Potential Key Genes and Molecular Mechanisms of Medulloblastoma Based on Integrated Bioinformatics Approach. PMID:35127939
Immune Checkpoint Gene Expression Profiling Identifies Programmed Cell Death Ligand-1 Centered Immunologic Subtypes of Oral and Squamous Cell Carcinoma With Favorable Survival. PMID:35127742
Identification of Key Genes and Pathways Involved in Circulating Tumor Cells in Colorectal Cancer. PMID:35127345
Functional New Transcription Factors (TFs) Associated with Cervical Cancer. PMID:35126951
Estrogen modulation of the pronociceptive effects of serotonin on female rat trigeminal sensory neurons is timing dependent and dosage dependent and requires estrogen receptor alpha. PMID:35121697
Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation. PMID:35119937
Anota2seq Analysis for Transcriptome-Wide Studies of mRNA Translation. PMID:35119670
Identification of biomarkers in colon cancer based on bioinformatic analysis. PMID:35117850
Construction and integrated analysis of a lncRNA-associated competing endogenous RNA network reveal functional lncRNAs in pancreatic cancer. PMID:35117727
Comprehensive analysis reveals a four-gene signature in colorectal cancer. PMID:35117487
Screening of hub genes associated with prognosis in non-small cell lung cancer by integrated bioinformatics analysis. PMID:35117319
Comprehensive analysis reveals novel gene signature in head and neck squamous cell carcinoma: predicting is associated with poor prognosis in patients. PMID:35117201
Bioinformatic analysis of long non-coding RNA-associated competing endogenous RNA network in adrenocortical carcinoma. PMID:35116967
Alternatively activated NUSAP1 promotes tumor growth and indicates poor prognosis in hepatocellular carcinoma. PMID:35116752
High expression of TXNDC11 indicated unfavorable prognosis of glioma. PMID:35116356
Surgical Trauma in Mice Modifies the Content of Circulating Extracellular Vesicles. PMID:35116043
Molecular Subtyping Resource: a user-friendly tool for rapid biological discovery from transcriptional data. PMID:35112706
Screening and identification of novel candidate biomarkers of focal cortical dysplasia type II via bioinformatics analysis. PMID:35112146
DDX10 promotes the proliferation and metastasis of colorectal cancer cells via splicing RPL35. PMID:35109823
Convergent clonal selection of donor- and recipient-derived CMV-specific T cells in hematopoietic stem cell transplant patients. PMID:35105810
Diagnostic Evidence GAuge of Single cells (DEGAS): a flexible deep transfer learning framework for prioritizing cells in relation to disease. PMID:35105355
Systems neuroimmunology: a review of multiomics methodologies to characterize neuroimmunological interactions in spinal and cranial diseases. PMID:35104798
Analytical kinetic model of native tandem promoters in E. coli. PMID:35100257
A Gene Prognostic Index Associated With Epithelial-Mesenchymal Transition Predicting Biochemical Recurrence and Tumor Chemoresistance for Prostate Cancer. PMID:35096608
Making sense of the linear genome, gene function and TADs. PMID:35090532
Early downregulation of hsa-miR-144-3p in serum from drug-naïve Parkinson's disease patients. PMID:35079043
Identification of key regulators in Sarcoidosis through multidimensional systems biological approach. PMID:35075176
Overexpression of chaperonin containing TCP1 subunit 7 has diagnostic and prognostic value for hepatocellular carcinoma. PMID:35073517
Identification of key genes associated with esophageal adenocarcinoma based on bioinformatics analysis. PMID:35071405
Immune response pathways enriched in breast cancer samples with brain metastasis. PMID:35070893
Establishment and characterization of NCC-DMM1-C1, a novel patient-derived cell line of desmoplastic malignant pleural mesothelioma. PMID:35069873
Identification of Characteristic Genes in Whole Blood of Intervertebral Disc Degeneration Patients by Weighted Gene Coexpression Network Analysis (WGCNA). PMID:35069789
Implication of Sphingolipid Metabolism Gene Dysregulation and Cardiac Sphingosine-1-Phosphate Accumulation in Heart Failure. PMID:35052814
MicroRNA-Enriched Exosomes from Different Sources of Mesenchymal Stem Cells Can Differentially Modulate Functions of Immune Cells and Neurogenesis. PMID:35052749
The Alzheimer's disease drug candidate J147 decreases blood plasma fatty acid levels via modulation of AMPK/ACC1 signaling in the liver. PMID:35051863
Identification of key genes and microRNAs for multiple sclerosis using bioinformatics analysis. PMID:35049167
Revealing potential diagnostic gene biomarkers of septic shock based on machine learning analysis. PMID:35045818
Identification of hub genes associated with COVID-19 and idiopathic pulmonary fibrosis by integrated bioinformatics analysis. PMID:35045126
Comparative analysis of protein-protein interaction networks in metastatic breast cancer. PMID:35045088
A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy. PMID:35039873
Identification of prognostic biomarkers in papillary renal cell carcinoma and PTTG1 may serve as a biomarker for predicting immunotherapy response. PMID:35037540
RiboReport - benchmarking tools for ribosome profiling-based identification of open reading frames in bacteria. PMID:35037022
Transcriptomic identification of HBx-associated hub genes in hepatocellular carcinoma. PMID:35036167
Key genes associated with prognosis and metastasis of clear cell renal cell carcinoma. PMID:35036081
PD-L1 interacts with Frizzled 6 to activate β-catenin and form a positive feedback loop to promote cancer stem cell expansion. PMID:35034965
Dictionary learning allows model-free pseudotime estimation of transcriptomic data. PMID:35033004
APOE4 confers transcriptomic and functional alterations to primary mouse microglia. PMID:35031484
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer. PMID:35028612
A method for simultaneous detection of small and long RNA biotypes by ribodepleted RNA-Seq. PMID:35022475
Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer. PMID:35022469
Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues. PMID:35022400
A lepidic gene signature predicts patient prognosis and sensitivity to immunotherapy in lung adenocarcinoma. PMID:35016696
[Identification of potential hub genes of Alzheimer's disease by weighted gene co-expression network analysis]. PMID:35012905
Enhancer RNA Expression in Response to Glucocorticoid Treatment in Murine Macrophages. PMID:35011590
The Antibiotic Fosfomycin Mimics the Effects of the Intermediate Metabolites Phosphoenolpyruvate and Glyceraldehyde-3-Phosphate on the Stenotrophomonas maltophilia Transcriptome. PMID:35008587
Anticancer Activities of 9-chloro-6-(piperazin-1-yl)-11H-indeno[1,2-c] quinolin-11-one (SJ10) in Glioblastoma Multiforme (GBM) Chemoradioresistant Cell Cycle-Related Oncogenic Signatures. PMID:35008426
IL-27 induces IFN/STAT1-dependent genes and enhances function of TIGIT+ HIVGag-specific T cells. PMID:35005538
ANXA9 as a novel prognostic biomarker associated with immune infiltrates in gastric cancer. PMID:35003923
Searching beyond the streetlight: Neonicotinoid exposure alters the neurogenomic state of worker honey bees. PMID:35003705
Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3. PMID:35001075
Human CD206+ macrophages associate with diabetes and adipose tissue lymphoid clusters. PMID:34990410
Integrative blood-derived epigenetic and transcriptomic analysis reveals the potential regulatory role of DNA methylation in ankylosing spondylitis. PMID:34986893
A versatile and robust cell purification system with an RNA-only circuit composed of microRNA-responsive ON and OFF switches. PMID:34985961
CREB1K292 and HINFPK330 as Putative Common Therapeutic Targets in Alzheimer's and Parkinson's Disease. PMID:34984308
Potential biomarkers and therapeutic targets of idiopathic pulmonary arterial hypertension. PMID:34981661
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues. PMID:34980912
CRISPR guides induce gene silencing in plants in the absence of Cas. PMID:34980227
The diagnostic and prognostic significance of small nuclear ribonucleoprotein Sm D1 aberrantly high expression in hepatocellular carcinoma. PMID:34976182
Expression profiling of lncRNAs and mRNAs in placental site trophoblastic tumor (PSTT) by microarray. PMID:34975294
Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion Molecules. PMID:34970543
The interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II. PMID:34967414
High Expression of CEMIP Correlates Poor Prognosis and the Tumur Microenvironment in Breast Cancer as a Promisingly Prognostic Biomarker. PMID:34966410
Bioinformatics study on different gene expression profiles of fibroblasts and vascular endothelial cells in keloids. PMID:34964740
Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord models early events in ERK-mediated tumorigenesis. PMID:34959031
Bacillus subtilis natto Derivatives Inhibit Enterococcal Biofilm Formation via Restructuring of the Cell Envelope. PMID:34956152
HPV16-LINC00393 Integration Alters Local 3D Genome Architecture in Cervical Cancer Cells. PMID:34950609
Autism-Related Transcription Factors Underlying the Sex-Specific Effects of Prenatal Bisphenol A Exposure on Transcriptome-Interactome Profiles in the Offspring Prefrontal Cortex. PMID:34947998
The Solvent Dimethyl Sulfoxide Affects Physiology, Transcriptome and Secondary Metabolism of Aspergillus flavus. PMID:34947037
hsa_circ_0001275 Is One of a Number of circRNAs Dysregulated in Enzalutamide Resistant Prostate Cancer and Confers Enzalutamide Resistance In Vitro. PMID:34945002
A Gene-Based Machine Learning Classifier Associated to the Colorectal Adenoma-Carcinoma Sequence. PMID:34944753
BET Proteins Regulate Expression of Osr1 in Early Kidney Development. PMID:34944697
C4d Deposition after Allogeneic Renal Transplantation in Rats Is Involved in Initial Apoptotic Cell Clearance. PMID:34944007
An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny. PMID:34942088
Adipose Tissue Dysfunctions in Response to an Obesogenic Diet Are Reduced in Mice after Transgenerational Supplementation with Omega 3 Fatty Acids. PMID:34940596
TIPE polarity proteins are required for mucosal deployment of T lymphocytes and mucosal defense against bacterial infection. PMID:34939151
sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs. PMID:34937774
Identification of potential key genes and functional role of CENPF in osteosarcoma using bioinformatics and experimental analysis. PMID:34934449
Identification of Potential Genetic Biomarkers and Target Genes of Peri-Implantitis Using Bioinformatics Tools. PMID:34931168
Carbon nanotube biocompatibility in plants is determined by their surface chemistry. PMID:34930290
Comprehensive analysis identifies IFI16 as a novel signature associated with overall survival and immune infiltration of skin cutaneous melanoma. PMID:34930258
Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting. PMID:34928942
Parallel Single-Cell Multiomics Analysis of Neonatal Skin Reveals the Transitional Fibroblast States that Restrict Differentiation into Distinct Fates. PMID:34922949
B cell-related gene signature and cancer immunotherapy response. PMID:34921229
Identification of potential biomarkers for diagnosis of hepatocellular carcinoma. PMID:34917180
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia. PMID:34914695
Col6a1+/CD201+ mesenchymal cells regulate intestinal morphogenesis and homeostasis. PMID:34910257
Deletion of TNFAIP6 Gene in Human Keratinocytes Demonstrates a Role for TSG-6 to Retain Hyaluronan Inside Epidermis. PMID:34909750
RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non-Metastatic Ovarian Cancer in Mice. PMID:34904285
Relation Extraction of Protein Complexes from Dynamic Protein-Protein Interaction Network. PMID:34904064
Supervised Methods for Biomarker Detection from Microarray Experiments. PMID:34902125
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. PMID:34900668
Structural Equation Modeling of In silico Perturbations. PMID:34899830
CoRE-ATAC: A deep learning model for the functional classification of regulatory elements from single cell and bulk ATAC-seq data. PMID:34898596
Analysis of a circRNA-, miRNA-, and mRNA-associated ceRNA network reveals potential biomarkers in preeclampsia a ceRNA network in preeclampsia. PMID:34894939
Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor. PMID:34894101
CAMML: Multi-Label Immune Cell-Typing and Stemness Analysis for Single-Cell RNA-sequencing. PMID:34890149
Canine DUXC: implications for DUX4 retrotransposition and preclinical models of FSHD. PMID:34888646
Organ Specific Copy Number Variations in Visceral Metastases of Human Melanoma. PMID:34885093
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells. PMID:34884975
Inference with Transposable Data: Modeling the Effects of Row and Column Correlations. PMID:34880705
Hirschsprung's disease: key microRNAs and target genes. PMID:34880446
Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection. PMID:34880107
Identifying the temporal electrophysiological and molecular changes that contribute to TSC-associated epileptogenesis. PMID:34877936
Sparse Regression in Cancer Genomics: Comparing Variable Selection and Predictions in Real World Data. PMID:34866896
Epigenome-wide association studies: current knowledge, strategies and recommendations. PMID:34863305
Manganese transport by Streptococcus sanguinis in acidic conditions and its impact on growth in vitro and in vivo. PMID:34862691
Large Multicohort Study Reveals a Prostate Cancer Susceptibility Allele at 5p15 Regulating TERT via Androgen Signaling-Orchestrated Chromatin Binding of E2F1 and MYC. PMID:34858826
Predicting Bone Metastasis Using Gene Expression-Based Machine Learning Models. PMID:34858485
The impact of fine particulate matter (PM) on various beneficial functions of human endometrial stem cells through its key regulator SERPINB2. PMID:34857902
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. PMID:34857879
Genomics and transcriptomics landscapes associated to changes in insulin sensitivity in response to endurance exercise training. PMID:34857871
A computational exploration of resilience and evolvability of protein-protein interaction networks. PMID:34857859
Why Environmental Biomarkers Work: Transcriptome-Proteome Correlations and Modeling of Multistressor Experiments in the Marine Bacterium Trichodesmium. PMID:34855411
JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles. PMID:34850907
The SAGA and NuA4 component Tra1 regulates Candida albicans drug resistance and pathogenesis. PMID:34849885
The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans. PMID:34849863
Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation. PMID:34849469
Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs. PMID:34848725
Glutamine deprivation triggers NAGK-dependent hexosamine salvage. PMID:34844667
Diagnostic and Prognostic Implications of Caspase-1 and PD-L1 Co-Expression Patterns in Myelodysplastic Syndromes. PMID:34830867
Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation. PMID:34830342
Circulatory Endothelin 1-Regulating RNAs Panel: Promising Biomarkers for Non-Invasive NAFLD/NASH Diagnosis and Stratification: Clinical and Molecular Pilot Study. PMID:34828420
The Identification of RNA Modification Gene PUS7 as a Potential Biomarker of Ovarian Cancer. PMID:34827123
Identification of Genes Potentially Associated with Melanoma Tumorigenesis Through Co-Expression Network Analysis. PMID:34824546
Genes and regulatory mechanisms associated with experimentally-induced bovine respiratory disease identified using supervised machine learning methodology. PMID:34824337
Effects of photodeoxygenation on cell biology using dibenzothiophene S-oxide derivatives as O(3P)-precursors. PMID:34822125
Establishment and characterization of prostate organoids from treatment-naïve patients with prostate cancer. PMID:34820005
Automatic cell type identification methods for single-cell RNA sequencing. PMID:34815832
Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury. PMID:34815787
Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance. PMID:34815424
Inheritance of gene expression throughout fruit development in chili pepper. PMID:34811443
A Single Human-Relevant Fast Food Meal Rapidly Reorganizes Metabolomic and Transcriptomic Signatures in a Gut Microbiota-Dependent Manner. PMID:34804604
The Macrophage Reprogramming Ability of Antifolates Reveals Soluble CD14 as a Potential Biomarker for Methotrexate Response in Rheumatoid Arthritis. PMID:34804067
Disruption of β-Catenin-Dependent Wnt Signaling in Colon Cancer Cells Remodels the Microenvironment to Promote Tumor Invasion. PMID:34799404
Identification of Immune-Related Genes for Establishment of Prognostic Index in Hepatocellular Carcinoma. PMID:34796177
CircleBase: an integrated resource and analysis platform for human eccDNAs. PMID:34792166
Identification of Cross-Pathway Connections via Protein-Protein Interactions Linked to Altered States of Metabolic Enzymes in Cervical Cancer. PMID:34790674
The Immune Infiltration in HNSCC and Its Clinical Value: A Comprehensive Study Based on the TCGA and GEO Databases. PMID:34790249
Sharing Biomedical Data Obtained Through Government-Funded Research and Development Projects in Korea. PMID:34788906
Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity. PMID:34784295
Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. PMID:34781035
TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes. PMID:34779419
Machine learning and network medicine approaches for drug repositioning for COVID-19. PMID:34778851
Nanolipoprotein-Mediated Her2 Protein Transfection Induces Malignant Transformation in Human Breast Acinar Cultures. PMID:34778614
Expression Levels of RAD51 Inversely Correlate with Survival of Glioblastoma Patients. PMID:34771522
ENPP2 Methylation in Health and Cancer. PMID:34769391
Computationally Reconstructed Interactome of Bradyrhizobium diazoefficiens USDA110 Reveals Novel Functional Modules and Protein Hubs for Symbiotic Nitrogen Fixation. PMID:34769335
Classification and Functional Analysis between Cancer and Normal Tissues Using Explainable Pathway Deep Learning through RNA-Sequencing Gene Expression. PMID:34768960
TRPA1 Expression and Pathophysiology in Immune Cells. PMID:34768891
Histone lysine demethylase 4B regulates general and unique gene expression signatures in hypoxic cancer cells. PMID:34766154
Computational methods for protein localization prediction. PMID:34765098
Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation. PMID:34763026
The Identified Hub Gene GlcN in Osteoarthritis Progression and Treatment. PMID:34754325
Identification of key molecular markers of acute coronary syndrome using peripheral blood transcriptome sequencing analysis and mRNA-lncRNA co-expression network construction. PMID:34753383
Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle. PMID:34752468
Epigenetic signature of chronic low back pain in human T cells. PMID:34746619
Aberrant Methylation and Immune Microenvironment Are Associated With Overexpressed Fibronectin 1: A Diagnostic and Prognostic Target in Head and Neck Squamous Cell Carcinoma. PMID:34746236
Identification of an Autophagy-Related Risk Signature Correlates With Immunophenotype and Predicts Immune Checkpoint Blockade Efficacy of Neuroblastoma. PMID:34746127
Evaluation of ATAD2 as a Potential Target in Hepatocellular Carcinoma. PMID:34738187
Mucosal-Associated Invariant T (MAIT) Cell Dysfunction and PD-1 Expression in Prostate Cancer: Implications for Immunotherapy. PMID:34737749
β-caryophyllene enhances the transcriptional upregulation of cholesterol biosynthesis in breast cancer cells. PMID:34733015
Progenitor translatome changes coordinated by Tsc1 increase perception of Wnt signals to end nephrogenesis. PMID:34732708
Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation. PMID:34728675
Single-cell RNA-sequencing analysis of the ciliary epithelium and contiguous tissues in the mouse eye. PMID:34717927
Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy. PMID:34711820
A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells. PMID:34711176
Molecular characterization of hematopoietic stem cells after in vitro amplification on biomimetic 3D PDMS cell culture scaffolds. PMID:34707135
Breast cancer dormancy is associated with a 4NG1 state and not senescence. PMID:34707097
Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma. PMID:34702271
PIM1 phosphorylation of the androgen receptor and 14-3-3 ζ regulates gene transcription in prostate cancer. PMID:34697370
Colon Cancer Progression Is Reflected to Monotonic Differentiation in Gene Expression and Pathway Deregulation Facilitating Stage-specific Drug Repurposing. PMID:34697067
Identification of C3 and FN1 as potential biomarkers associated with progression and prognosis for clear cell renal cell carcinoma. PMID:34688260
Nkx3-1 and Fech genes might be switch genes involved in pituitary non-functioning adenoma invasiveness. PMID:34686726
Nanosecond Pulsed Electric Field Only Transiently Affects the Cellular and Molecular Processes of Leydig Cells. PMID:34681896
Trends in oligomannosylation and α1,2-mannosidase expression in human cancers. PMID:34676051
Construction and Investigation of Competing Endogenous RNA Networks and Candidate Genes Involved in SARS-CoV-2 Infection. PMID:34675627
Proteomic analysis of the host-pathogen interface in experimental cholera. PMID:34675415
Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ. PMID:34671716
Integrated computational analyses reveal novel insights into the stromal microenvironment of SHH-subtype medulloblastoma. PMID:34667228
Nrd1p identifies aberrant and natural exosomal target messages during the nuclear mRNA surveillance in Saccharomyces cerevisiae. PMID:34664673
Identification of key genes for HNSCC from public databases using bioinformatics analysis. PMID:34663338
Pleiotropic Effects of the P5-Type ATPase SpfA on Stress Response Networks Contribute to Virulence in the Pathogenic Mold Aspergillus fumigatus. PMID:34663092
IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses. PMID:34659203
Computational Interspecies Translation Between Alzheimer's Disease Mouse Models and Human Subjects Identifies Innate Immune Complement, TYROBP, and TAM Receptor Agonist Signatures, Distinct From Influences of Aging. PMID:34658769
A robust mean and variance test with application to high-dimensional phenotypes. PMID:34651232
Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan. PMID:34650272
GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses. PMID:34650124
A brain-specific pgc1α fusion transcript affects gene expression and behavioural outcomes in mice. PMID:34649938
Meta-Analysis illustrates possible role of lipopolysaccharide (LPS)-induced tissue injury in nasopharyngeal carcinoma (NPC) pathogenesis. PMID:34648530
A novel m6A-related prognostic signature for predicting the overall survival of hepatocellular carcinoma patients. PMID:34647424
Oestrogen engages brain MC4R signalling to drive physical activity in female mice. PMID:34646010
The network interplay of interferon and Toll-like receptor signaling pathways in the anti-Candida immune response. PMID:34645905
A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. PMID:34644528
Transcriptional Profiling of the Candida auris Response to Exogenous Farnesol Exposure. PMID:34643421
Comparison of the Metastasis Predictive Potential of mRNA and Long Non-Coding RNA Profiling in Systemically Untreated Breast Cancer. PMID:34638391
Evaluation of Comprehensive Gene Expression and NK Cell-Mediated Killing in Glioblastoma Cell Line-Derived Spheroids. PMID:34638384
The Role of miRNAs 340-5p, 92a-3p, and 381-3p in Patients with Endometriosis: A Plasma and Mesenchymal Stem-Like Cell Study. PMID:34631883
SPT6 loss permits the transdifferentiation of keratinocytes into an intestinal fate that resembles Barrett's metaplasia. PMID:34622168
Identification of immunization-related new prognostic biomarkers for papillary renal cell carcinoma by integrated bioinformatics analysis. PMID:34620162
Neuronal activity regulates the nuclear proteome to promote activity-dependent transcription. PMID:34617965
Lipocalin 2 Is a Regulator During Macrophage Polarization Induced by Soluble Worm Antigens. PMID:34616693
A dual-function RNA balances carbon uptake and central metabolism in Vibrio cholerae. PMID:34612526
Antimelanoma Effects of Concomitant Inhibition of SIRT1 and SIRT3 in BrafV600E/PtenNULL Mice. PMID:34597611
The profile analysis of circular RNAs in cervical cancer. PMID:34596168
A 41-Gene Pair Signature for Predicting the Pathological Response of Locally Advanced Rectal Cancer to Neoadjuvant Chemoradiation. PMID:34595195
The Interactions of Small Proline-Rich Proteins with Late Cornified Envelope Proteins are Involved in the Pathogenesis of Psoriasis. PMID:34594126
Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program. PMID:34589771
Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy: Development of PLN-R14del-Related Cardiomyopathy. PMID:34587756
Transcriptome dataset of ethylene-treated Klutuk Wulung banana. PMID:34584916
Deep learning in cancer diagnosis, prognosis and treatment selection. PMID:34579788
Bioinformatic Analysis for Influential Core Gene Identification and Prognostic Significance in Advanced Serous Ovarian Carcinoma. PMID:34577856
RNA-Seq Provides New Insights into the Gene Expression Changes in Azoarcus olearius BH72 under Nitrogen-Deficient and Replete Conditions beyond the Nitrogen Fixation Process. PMID:34576783
Anaesthesia-Induced Transcriptomic Changes in the Context of Renal Ischemia Uncovered by the Use of a Novel Clamping Device. PMID:34576005
Searching for Biological Function of the Mysterious PA2504 Protein from Pseudomonas aeruginosa. PMID:34575996
Progression Risk Score Estimation Based on Immunostaining Data in Oral Cancer Using Unsupervised Hierarchical Clustering Analysis: A Retrospective Study in Taiwan. PMID:34575686
Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea. PMID:34572983
The amino acid substitution affects cellular response to mistranslation. PMID:34568909
Position Specific Alternative Splicing and Gene Expression Profiles Along the Tonotopic Axis of Chick Cochlea. PMID:34568429
Limited Impact of Pivalate-Induced Secondary Carnitine Deficiency on Hepatic Transcriptome and Hepatic and Plasma Metabolome in Nursery Pigs. PMID:34564388
Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung. PMID:34561242
Expression and prognosis of CDC45 in cervical cancer based on the GEO database. PMID:34557356
Reciprocal transcription factor networks govern tissue-resident ILC3 subset function and identity. PMID:34556884
ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. PMID:34556859
Association between chronic periodontitis and the risk of Alzheimer's disease: combination of text mining and GEO dataset. PMID:34556089
Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases. PMID:34552089
Elevated Levels of the Escherichia coli nrdAB-Encoded Ribonucleotide Reductase Counteract the Toxicity Caused by an Increased Abundance of the β Clamp. PMID:34543109
The Mutant βE202K Sliding Clamp Protein Impairs DNA Polymerase III Replication Activity. PMID:34543108
Circular RNA repertoires are associated with evolutionarily young transposable elements. PMID:34542406
Programmed Cell Death Protein 1/Programmed Cell Death Ligand-1 Axis activates Intracellular ERK Signaling in Tumor Cells to Mediate Poor Prognosis in T-cell Lymphoma. PMID:34539885
High light and temperature reduce photosynthetic efficiency through different mechanisms in the C4 model Setaria viridis. PMID:34531541
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics. PMID:34529976
Computational drug repositioning of atorvastatin for ulcerative colitis. PMID:34529084
Prognostic impact of a lymphocyte activation-associated gene signature in GBM based on transcriptome analysis. PMID:34527446
Understanding Competitive Endogenous RNA Network Mechanism in Type 1 Diabetes Mellitus Using Computational and Bioinformatics Approaches. PMID:34526791
Meta-analysis of gene expression disease signatures in colonic biopsy tissue from patients with ulcerative colitis. PMID:34521888
The Complex Transcriptional Landscape of Magnetosome Gene Clusters in Magnetospirillum gryphiswaldense. PMID:34519524
Comparative analysis of RNA enrichment methods for preparation of Cryptococcus neoformans RNA sequencing libraries. PMID:34518880
Tissue heterogeneity is prevalent in gene expression studies. PMID:34514392
RNA Sequence Profiling Reveals Unique Immune and Metabolic Features of Breast Cancer Brain Metastases. PMID:34513670
Prediction of the mechanism of miRNAs in laryngeal squamous cell carcinoma based on the miRNA-mRNA regulatory network. PMID:34513340
Identification of Genes Encoding Antimicrobial Proteins in Langerhans Cells. PMID:34512625
Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa. PMID:34504848
Protein-gene Expression Nexus: Comprehensive characterization of human cancer cell lines with proteogenomic analysis. PMID:34504668
Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight. PMID:34502375
Investigating the Molecular Processes behind the Cell-Specific Toxicity Response to Titanium Dioxide Nanobelts. PMID:34502343
Herbaspirillum seropedicae expresses non-phosphorylative pathways for D-xylose catabolism. PMID:34499201
Identification of a novel six-gene signature with potential prognostic and therapeutic value in cervical cancer. PMID:34498424
Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease. PMID:34497069
An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks. PMID:34496885
Functional characterization of a highly specific L-arabinose transporter from Trichoderma reesei. PMID:34496831
Dysregulation of KIF14 regulates the cell cycle and predicts poor prognosis in cervical cancer: a study based on integrated approaches. PMID:34495250
Two distinct Sertoli cell states are regulated via germ cell crosstalk†. PMID:34494084
Direct and Indirect Transcriptional Effects of Abiotic Stress in Zea mays Plants Defective in RNA-Directed DNA Methylation. PMID:34489998
Computational challenges and opportunities in spatially resolved transcriptomic data analysis. PMID:34489425
Disrupting biological sensors of force promotes tissue regeneration in large organisms. PMID:34489407
Carcinogenic effect of adenylosuccinate lyase (ADSL) in prostate cancer development and progression through the cell cycle pathway. PMID:34488772
Dataset for: Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC)-derived sensory neurons. PMID:34485650
Identification of a prognostic 4-mRNA signature in laryngeal squamous cell carcinoma. PMID:34475994
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms. PMID:34473231
A computational approach for identification of core modules from a co-expression network and GWAS data. PMID:34467232
Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19. PMID:34463615
Reproducibility standards for machine learning in the life sciences. PMID:34462593
N6-methyladenosine (m6A) modification and its clinical relevance in cognitive dysfunctions. PMID:34461609
A multi-objective genetic algorithm to find active modules in multiplex biological networks. PMID:34460810
Annotating cell types in human single-cell RNA-seq data with CellO. PMID:34458864
Transcriptome Alterations of an in vitro-Selected, Moderately Resistant, Two-Row Malting Barley in Response to 3ADON, 15ADON, and NIV Chemotypes of Fusarium graminearum. PMID:34456945
New Insights Into Mitochondrial Dysfunction at Disease Susceptibility Loci in the Development of Type 2 Diabetes. PMID:34456865
PCA-based unsupervised feature extraction for gene expression analysis of COVID-19 patients. PMID:34456333
FluB-RAM and FluB-RANS: Genome Rearrangement as Safe and Efficacious Live Attenuated Influenza B Virus Vaccines. PMID:34452022
Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction. PMID:34447638
Exploring the role of monocyte chemoattractant protein-1 in fibroblast-like synovial cells in rheumatoid arthritis. PMID:34447637
HOXB8 Counteracts MAPK/ERK Oncogenic Signaling in a Chicken Embryo Model of Neoplasia. PMID:34445617
Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin. PMID:34445339
A Novel Approach for the Discovery of Biomarkers of Radiotherapy Response in Breast Cancer. PMID:34442440
Artificial Intelligence for Alzheimer's Disease: Promise or Challenge? PMID:34441407
Two Auxinic Herbicides Affect Brassica napus Plant Hormone Levels and Induce Molecular Changes in Transcription. PMID:34439819
Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD). PMID:34439758
CCL20/TNF/VEGFA Cytokine Secretory Phenotype of Tumor-Associated Macrophages Is a Negative Prognostic Factor in Cutaneous Melanoma. PMID:34439098
The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children. PMID:34437303
The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms. PMID:34433046
Perturbed transcriptional profiles after chronic low dose rate radiation in mice. PMID:34428250
Assessment of the Diagnostic Efficiency of a Liquid Biopsy Assay for Early Detection of Gastric Cancer. PMID:34427680
Genotypic Characteristics of Hepatoblastoma as Detected by Next Generation Sequencing and Their Correlation With Clinical Efficacy. PMID:34426785
INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants. PMID:34425882
Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages. PMID:34423778
Identification of JAK2 and FOXM1 expression as novel candidate biomarkers for predicting the benefit of immunotherapy in lung squamous cell carcinoma. PMID:34422993
Hypoxia-Inducible Factor 2-Alpha Mediated Gene Sets Differentiate Pulmonary Arterial Hypertension. PMID:34422822
CD86 Molecule Might Be a Novel Immune-Related Prognostic Biomarker for Patients With Bladder Cancer by Bioinformatics and Experimental Assays. PMID:34422632
Gene Set Enrichment Analysis Reveals Individual Variability in Host Responses in Tuberculosis Patients. PMID:34421903
Transcriptional Time Course After Rotator Cuff Tear. PMID:34421646
Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes. PMID:34417450
RHPN1‑AS1 promotes ovarian carcinogenesis by sponging miR‑6884‑5p thus releasing TOP2A mRNA. PMID:34414458
Large-scale transcriptome-wide profiling of microRNAs in human placenta and maternal plasma at early to mid gestation. PMID:34412547
Cerium Oxide Nanoparticle Administration to Skeletal Muscle Cells under Different Gravity and Radiation Conditions. PMID:34410709
Chronic social isolation signals starvation and reduces sleep in Drosophila. PMID:34408325
Key features of the environment promoting liver cancer in the absence of cirrhosis. PMID:34408183
Long non-coding RNA RP4-694A7.2 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the Regulation of PSAT1. PMID:34405023
Transcriptomic analysis of the mouse retina after acute and chronic normobaric and hypobaric hypoxia. PMID:34404875
Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro. PMID:34404774
A primary cell wall cellulose-dependent defense mechanism against vascular pathogens revealed by time-resolved dual transcriptomics. PMID:34404410
The Rsm (Csr) post-transcriptional regulatory pathway coordinately controls multiple CRISPR-Cas immune systems. PMID:34403463
Metabolic preconditioning in CD4+ T cells restores inducible immune tolerance in lupus-prone mice. PMID:34403367
MiR-508-3p promotes proliferation and inhibits apoptosis of middle ear cholesteatoma cells by targeting PTEN/PI3K/AKT pathway. PMID:34400892
Integrated bioinformatics analysis reveals CDK1 and PLK1 as potential therapeutic targets of lung adenocarcinoma. PMID:34397869
Multi-omics network characterization reveals novel microRNA biomarkers and mechanisms for diagnosis and subtyping of kidney transplant rejection. PMID:34389032
ERK signaling controls productive HIF-1 binding to chromatin and cancer cell adaptation to hypoxia through HIF-1α interaction with NPM1. PMID:34388291
The epithelial potassium channel Kir7.1 is stimulated by progesterone. PMID:34387656
NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice. PMID:34385484
Replacement of Nitrite in Meat Products by Natural Bioactive Compounds Results in Reduced Exposure to N-Nitroso Compounds: The PHYTOME Project. PMID:34382747
A merged microarray meta-dataset for transcriptionally profiling colorectal neoplasm formation and progression. PMID:34381057
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer. PMID:34381019
Lack of Interferon (IFN) Regulatory Factor 8 Associated with Restricted IFN-γ Response Augmented Japanese Encephalitis Virus Replication in the Mouse Brain. PMID:34379515
KITlow Cells Mediate Imatinib Resistance in Gastrointestinal Stromal Tumor. PMID:34376580
Human Placental Trophoblasts Infected by Listeria monocytogenes Undergo a Pro-Inflammatory Switch Associated With Poor Pregnancy Outcomes. PMID:34367171
Gene Expression Meta-Analysis Reveals Interferon-Induced Genes Associated With SARS Infection in Lungs. PMID:34367154
Volatile Compounds From Bacillus, Serratia, and Pseudomonas Promote Growth and Alter the Transcriptional Landscape of Solanum tuberosum in a Passively Ventilated Growth System. PMID:34367077
Distinct regulation of hippocampal neuroplasticity and ciliary genes by corticosteroid receptors. PMID:34362910
NAT10 as a potential prognostic biomarker and therapeutic target for HNSCC. PMID:34362389
mRNA Inventory of Extracellular Vesicles from Ustilago maydis. PMID:34356940
The Negative Effect of Protein Phosphatase Z1 Deletion on the Oxidative Stress Tolerance of Candida albicans Is Synergistic with Betamethasone Exposure. PMID:34356919
Delayed Contralateral Nephrectomy Halted Post-Ischemic Renal Fibrosis Progression and Inhibited the Ischemia-Induced Fibromir Upregulation in Mice. PMID:34356879
Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity. PMID:34354145
Personalized single-cell networks: a framework to predict the response of any gene to any drug for any patient. PMID:34353329
Tomato transcriptomic response to Tuta absoluta infestation. PMID:34348650
Long non-coding RNA profile study identifies a metabolism-related signature for colorectal cancer. PMID:34344319
Spatial transcriptomics analysis of uterine gene expression in enhancer of zeste homolog 2 conditional knockout mice†. PMID:34344022
The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells. PMID:34339468
Does chronic dietary exposure to the mycotoxin deoxynivalenol affect the porcine hepatic transcriptome when an acute-phase response is initiated through first or second-pass LPS challenge of the liver? PMID:34338001
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. PMID:34337362
Creation of a Single Cell RNASeq Meta-Atlas to Define Human Liver Immune Homeostasis. PMID:34335581
Epigenetic Analysis of the Chromatin Landscape Identifies a Repertoire of Murine Eosinophil-Specific PU.1-Bound Enhancers. PMID:34330753
Somatic cell hemoglobin modulates nitrogen oxide metabolism in the human airway epithelium. PMID:34326365
RNA sequencing identifies global transcriptional changes in peripheral CD4+ cells during active oesophagitis and following epicutaneous immunotherapy in eosinophilic oesophagitis. PMID:34322233
On the impact of batch effect correction in TCGA isomiR expression data. PMID:34316700
Transcriptional landscape of PTEN loss in primary prostate cancer. PMID:34311724
Identification of novel survival-related lncRNA-miRNA-mRNA competing endogenous RNA network associated with immune infiltration in colorectal cancer. PMID:34306328
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis. PMID:34306156
A pH-eQTL Interaction at the RIT2-SYT4 Parkinson's Disease Risk Locus in the Substantia Nigra. PMID:34305570
Myeloid Cells Are Enriched in Tonsillar Crypts, Providing Insight into the Viral Tropism of Human Papillomavirus. PMID:34303699
Investigation of Fascin1, a Marker of Mature Dendritic Cells, Reveals a New Role for IL-6 Signaling in CCR7-Mediated Chemotaxis. PMID:34301846
Whole Blood Transcriptome Characterization of 3xTg-AD Mouse and Its Modulation by Transcranial Direct Current Stimulation (tDCS). PMID:34299250
Genomic and clinical characterization of early T-cell precursor lymphoblastic lymphoma. PMID:34297047
Screening of hub genes and evaluation of the growth regulatory role of CD44 in metastatic prostate cancer. PMID:34296309
IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer. PMID:34290237
Transcriptomic changes in peripheral blood mononuclear cells with weight loss: systematic literature review and primary data synthesis. PMID:34281497
The methyl donor S-adenosyl methionine reverses the DNA methylation signature of chronic neuropathic pain in mouse frontal cortex. PMID:34278163
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages. PMID:34276591
Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity. PMID:34276573
The Progenetix oncogenomic resource in 2021. PMID:34272855
Analysis of the Prognostic Value and Gene Expression Mechanism of SHOX2 in Lung Adenocarcinoma. PMID:34262939
Identification of four key biomarkers and small molecule drugs in nasopharyngeal carcinoma by weighted gene co-expression network analysis. PMID:34261404
Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis. PMID:34257800
Linking genotype to phenotype in multi-omics data of small sample. PMID:34256701
CD40L modulates transcriptional signatures of neutrophils in the bone marrow associated with development and trafficking. PMID:34255742
Accurate transcriptome assembly by Nanopore RNA sequencing reveals novel functional transcripts in hepatocellular carcinoma. PMID:34255396
Targeting Bacterial Gyrase with Cystobactamid, Fluoroquinolone, and Aminocoumarin Antibiotics Induces Distinct Molecular Signatures in Pseudomonas aeruginosa. PMID:34254824
Predicting mechanism of action of novel compounds using compound structure and transcriptomic signature coembedding. PMID:34252937
'Single-subject studies'-derived analyses unveil altered biomechanisms between very small cohorts: implications for rare diseases. PMID:34252934
Loss of RND-Type Multidrug Efflux Pumps Triggers Iron Starvation and Lipid A Modifications in Pseudomonas aeruginosa. PMID:34252310
Detecting Differentially Methylated Promoters in Genes Related to Disease Phenotypes Using R. PMID:34250201
Bioinformatics Analysis Reveals Crosstalk Among Platelets, Immune Cells, and the Glomerulus That May Play an Important Role in the Development of Diabetic Nephropathy. PMID:34249963
Role of NRP1 in Bladder Cancer Pathogenesis and Progression. PMID:34249735
Prolonged cadmium exposure alters benign uterine fibroid cell behavior, extracellular matrix components, and TGFB signaling. PMID:34245615
MicroRNA-378a-3p is overexpressed in psoriasis and modulates cell cycle arrest in keratinocytes via targeting BMP2 gene. PMID:34244572
Integrative analysis of key candidate genes and signaling pathways in acute coronary syndrome related to obstructive sleep apnea by bioinformatics. PMID:34239024
Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches. PMID:34237135
Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy. PMID:34236518
Combining multiomics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy. PMID:34236053
DIMEimmune: Robust estimation of infiltrating lymphocytes in CNS tumors from DNA methylation profiles. PMID:34235002
Screening of key biomarkers and immune infiltration in Pulmonary Arterial Hypertension via integrated bioinformatics analysis. PMID:34233597
Active elimination of intestinal cells drives oncogenic growth in organoids. PMID:34233177
Identification of endometriosis-associated genes and pathways based on bioinformatic analysis. PMID:34232189
GNRH1 and LTB4R might be novel immune-related prognostic biomarkers in clear cell renal cell carcinoma (ccRCC). PMID:34229684
Identification of immune-infiltrating cell-related biomarkers in hepatocellular carcinoma based on gene co-expression network analysis. PMID:34218795
Regular football training down-regulates miR-1303 muscle expression in veterans. PMID:34212217
The Placental Response to Guinea Pig Cytomegalovirus Depends Upon the Timing of Maternal Infection. PMID:34211475
Profile of miR-23 Expression and Possible Role in Regulation of Glutamic Acid Decarboxylase during Postnatal Retinal Development. PMID:34209226
Diversity of Rainbow Trout Blood B Cells Revealed by Single Cell RNA Sequencing. PMID:34207643
Cleaning the Medicago Microarray Database to Improve Gene Function Analysis. PMID:34207216
Methylation Status of Corticotropin-Releasing Factor (CRF) Receptor Genes in Colorectal Cancer. PMID:34207031
Serine-Threonine Kinase Receptor-Associated Protein (STRAP) Knockout Decreases the Malignant Phenotype in Neuroblastoma Cell Lines. PMID:34206917
MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA. PMID:34206143
Exploring the Metabolic Heterogeneity of Cancers: A Benchmark Study of Context-Specific Models. PMID:34205912
Statistical Integration of 'Omics Data Increases Biological Knowledge Extracted from Metabolomics Data: Application to Intestinal Exposure to the Mycotoxin Deoxynivalenol. PMID:34205708
Differential Regulation of Gonadotropins as Revealed by Transcriptomes of Distinct LH and FSH Cells of Fish Pituitary. PMID:34204216
TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer. PMID:34203408
mRNA-miRNA-lncRNA Regulatory Network in Nonalcoholic Fatty Liver Disease. PMID:34202571
Virus-Host Interaction Gets Curiouser and Curiouser. PART II: Functional Transcriptomics of the E. coli DksA-Deficient Cell upon Phage P1vir Infection. PMID:34200430
Biphasic α2β1 Integrin Expression in Breast Cancer Metastasis to Bone. PMID:34199096
Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein. PMID:34198994
Tribbles Pseudokinases in Colorectal Cancer. PMID:34198908
Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms. PMID:34197603
Genome of the Single Human Chromosome 18 as a "Gold Standard" for Its Transcriptome. PMID:34194472
Pars Pro Toto: Every Single Cell Matters. PMID:34194448
Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration. PMID:34192530
Protocol for using heterologous spike-ins to normalize for technical variation in chromatin immunoprecipitation. PMID:34189474
Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. PMID:34188052
Conservation genomics reveals pesticide and pathogen exposure in the declining bumble bee Bombus terricola. PMID:34181797
Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer. PMID:34181531
Classifying Medulloblastoma Subgroups Based on Small, Clinically Achievable Gene Sets. PMID:34178626
Predicting Selective RNA Processing and Stabilization Operons in Clostridium spp. PMID:34177856
Bioinformatics analysis of differentially expressed genes and pathways in the development of cervical cancer. PMID:34174849
UniBind: maps of high-confidence direct TF-DNA interactions across nine species. PMID:34174819
Altered expression of SARS-CoV-2 entry and processing genes by Porphyromonas gingivalis-derived lipopolysaccharide, inflammatory cytokines and prostaglandin E2 in human gingival fibroblasts. PMID:34174588
A comprehensive database for integrated analysis of omics data in autoimmune diseases. PMID:34167460
Identification of Independent and Communal Differentially Expressed Genes as Well as Potential Therapeutic Targets in Ischemic Heart Failure and Non-Ischemic Heart Failure. PMID:34163213
Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation. PMID:34163009
A method to analyze time expression profiles demonstrated in a database of chili pepper fruit development. PMID:34162966
Side effect prediction based on drug-induced gene expression profiles and random forest with iterative feature selection. PMID:34155353
A small RNA regulates pprM, a modulator of pleiotropic proteins promoting DNA repair, in Deinococcus radiodurans under ionizing radiation. PMID:34155239
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans. PMID:34154419
Identification of NAA40 as a Potential Prognostic Marker for Aggressive Liver Cancer Subtypes. PMID:34150665
Identification of a Competing Endogenous RNA Network Related to Immune Signature in Lung Adenocarcinoma. PMID:34149807
Transcriptome Analysis Reveals Putative Target Genes of APETALA3-3 During Early Floral Development in Nigella damascena L. PMID:34149759
hsp-90 and unc-45 depletion induce characteristic transcriptional signatures in coexpression cliques of C. elegans. PMID:34145311
ATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoids. PMID:34142370
Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish. PMID:34142062
DCBLD1 is associated with the integrin signaling pathway and has prognostic value in non-small cell lung and invasive breast carcinoma. PMID:34140574
Analysis of the transcriptome of bovine endometrial cells isolated by laser micro-dissection (1): specific signatures of stromal, glandular and luminal epithelial cells. PMID:34139994
Analysis of the transcriptome of bovine endometrial cells isolated by laser micro-dissection (2): impacts of post-partum negative energy balance on stromal, glandular and luminal epithelial cells. PMID:34139988
Transcriptional analysis of sweet corn hybrids in response to crowding stress. PMID:34138910
Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice. PMID:34138760
The Immunology of Hormone Receptor Positive Breast Cancer. PMID:34135901
The Gene Expression Profile of the Song Control Nucleus HVC Shows Sex Specificity, Hormone Responsiveness, and Species Specificity Among Songbirds. PMID:34135731
Insulin Infusion Is Linked to Increased NPPC Expression in Muscle and Plasma C-type Natriuretic Peptide in Male Dogs. PMID:34131611
Capitalizing on transcriptome profiling to optimize and identify targets for promoting early murine folliculogenesis in vitro. PMID:34131220
Transcriptional drug repositioning and cheminformatics approach for differentiation therapy of leukaemia cells. PMID:34131166
IOAT: an interactive tool for statistical analysis of omics data and clinical data. PMID:34130622
Copy number alterations identify a smoking-associated expression signature predictive of poor outcome in head and neck squamous cell carcinoma. PMID:34130230
AI-guided discovery of the invariant host response to viral pandemics. PMID:34127431
TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data. PMID:34125906
Differences in the genome, methylome, and transcriptome do not differentiate isolates of Streptococcus equi subsp. equi from horses with acute clinical signs from isolates of inapparent carriers. PMID:34125848
The ChvG-ChvI and NtrY-NtrX Two-Component Systems Coordinately Regulate Growth of Caulobacter crescentus. PMID:34124942
Investigation of the Mechanism of Complement System in Diabetic Nephropathy via Bioinformatics Analysis. PMID:34124269
Murine Blastocysts Release Mature MicroRNAs Into Culture Media That Reflect Developmental Status. PMID:34122510
Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis. PMID:34122426
Transcriptome Analysis Reveals Cr(VI) Adaptation Mechanisms in Klebsiella sp. Strain AqSCr. PMID:34122372
Identification of Key Biomarkers and Immune Infiltration in Sciatic Nerve of Diabetic Neuropathy BKS-db/db Mice by Bioinformatics Analysis. PMID:34122109
Noncanonical functions of glucocorticoids: A novel role for glucocorticoids in performing multiple beneficial functions in endometrial stem cells. PMID:34120144
Identification of Disease-Specific Hub Biomarkers and Immune Infiltration in Osteoarthritis and Rheumatoid Arthritis Synovial Tissues by Bioinformatics Analysis. PMID:34113405
Exploration of Crucial Mediators for Carotid Atherosclerosis Pathogenesis Through Integration of Microbiome, Metabolome, and Transcriptome. PMID:34108883
Time trajectories in the transcriptomic response to exercise - a meta-analysis. PMID:34108459
Decoding empagliflozin's molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence. PMID:34103605
Transcriptomic analysis of cork during seasonal growth highlights regulatory and developmental processes from phellogen to phellem formation. PMID:34103550
Gene expression changes and DNA damage after ex vivo exposure of peripheral blood cells to various CT photon spectra. PMID:34103547
Type II alveolar epithelial cell-specific loss of RhoA exacerbates allergic airway inflammation through SLC26A4. PMID:34101619
Molecular omics resources should require sex annotation: a call for action. PMID:34099934
A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation. PMID:34099688
HOXA13 in etiology and oncogenic potential of Barrett's esophagus. PMID:34099670
A Dynamic Transcription Factor Signature Along the Colorectal Adenoma-Carcinoma Sequence in Patients With Co-Occurrent Adenoma and Carcinoma. PMID:34094897
Differentially Expressed Genes and Enriched Signaling Pathways in the Adipose Tissue of Obese People. PMID:34093637
Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance. PMID:34088870
Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1. PMID:34082786
Continuous Inflammatory Stimulation Leads via Metabolic Plasticity to a Prometastatic Phenotype in Triple-Negative Breast Cancer Cells. PMID:34072893
Transcriptome Profiling of Embryonic Retinal Pigment Epithelium Reprogramming. PMID:34072522
Small RNA-Sequencing: Approaches and Considerations for miRNA Analysis. PMID:34071824
Pivotal Role for Cxcr2 in Regulating Tumor-Associated Neutrophil in Breast Cancer. PMID:34070438
Transcription Factor β-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney. PMID:34069476
Microarray and qPCR Analysis of Mitochondrial Metabolism Activation during Prenatal and Early Postnatal Development in Rats and Humans with Emphasis on CoQ10 Biosynthesis. PMID:34066731
Transcriptomic Profiling of Skeletal Muscle Reveals Candidate Genes Influencing Muscle Growth and Associated Lipid Composition in Portuguese Local Pig Breeds. PMID:34065673
Application of the Interaction between Tissue Immunohistochemistry Staining and Clinicopathological Factors for Evaluating the Risk of Oral Cancer Progression by Hierarchical Clustering Analysis: A Case-Control Study in a Taiwanese Population. PMID:34063938
Effect of Ecdysterone on the Hepatic Transcriptome and Lipid Metabolism in Lean and Obese Zucker Rats. PMID:34063487
Death Processes in Bovine Theca and Granulosa Cells Modelled and Analysed Using a Systems Biology Approach. PMID:34063056
GeromiRs Are Downregulated in the Tumor Microenvironment during Colon Cancer Colonization of the Liver in a Murine Metastasis Model. PMID:34062897
Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma. PMID:34060480
GLEANER: a web server for GermLine cycle Expression ANalysis and Epigenetic Roadmap visualization. PMID:34058973
Pro-inflammatory Monocyte Phenotype During Acute Progression of Cerebral Small Vessel Disease. PMID:34055930
Prediction of clinical prognosis in cutaneous melanoma using an immune-related gene pair signature. PMID:34047683
MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer. PMID:34045467
RNA Sequencing Reveals Key Metabolic Pathways Are Modified by Short-Term Whole Egg Consumption. PMID:34041258
In vivo stabilization of endogenous chloroplast RNAs by customized artificial pentatricopeptide repeat proteins. PMID:34037778
MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro. PMID:34035375
Tutorial: guidelines for annotating single-cell transcriptomic maps using automated and manual methods. PMID:34031612
NFAT5 Amplifies Antipathogen Responses by Enhancing Chromatin Accessibility, H3K27 Demethylation, and Transcription Factor Recruitment. PMID:34031145
Application of multi-omics data integration and machine learning approaches to identify epigenetic and transcriptomic differences between in vitro and in vivo produced bovine embryos. PMID:34029343
Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. PMID:34029205
The relationship between cytokine and neutrophil gene network distinguishes SARS-CoV-2-infected patients by sex and age. PMID:34027897
Network-based analysis of key regulatory genes implicated in Type 2 Diabetes Mellitus and Recurrent Miscarriages in Turner Syndrome. PMID:34021221
eVITTA: a web-based visualization and inference toolbox for transcriptome analysis. PMID:34019643
Hub biomarkers for the diagnosis and treatment of glioblastoma based on microarray technology. PMID:34018447
Deep Large-Scale Multitask Learning Network for Gene Expression Inference. PMID:34014778
Identification of the EMT-Related Genes Signature for Predicting Occurrence and Progression in Thyroid Cancer. PMID:34012269
Genome-wide screening of SARS-CoV-2 infection-related genes based on the blood leukocytes sequencing data set of patients with COVID-19. PMID:34009691
Activated mast cells in skeletal muscle can be a potential mediator for cancer-associated cachexia. PMID:34008339
The ApiAP2 factor PfAP2-HC is an integral component of heterochromatin in the malaria parasite Plasmodium falciparum. PMID:33997710
Evaluating the Consistency of Gene Methylation in Liver Cancer Using Bisulfite Sequencing Data. PMID:33996828
Identification of Key Functional Gene Signatures Indicative of Dedifferentiation in Papillary Thyroid Cancer. PMID:33996555
Role of Flt4 in Skin Protection against UVB Radiation: A System Biology Approach. PMID:33995966
Genome-wide analysis of primary microRNA expression using H3K36me3 ChIP-seq data. PMID:33995896
Identifying the Potential Therapeutic Targets for Atopic Dermatitis Through the Immune Infiltration Analysis and Construction of a ceRNA Network. PMID:33994801
Centromere protein N may be a novel malignant prognostic biomarker for hepatocellular carcinoma. PMID:33987018
A surgical method for continuous intraportal infusion of gut microbial metabolites in mice. PMID:33986195
CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity. PMID:33986188
Molecular Regulation of the Melatonin Biosynthesis Pathway in Unipolar and Bipolar Depression. PMID:33981243
Cbl-b deficiency prevents functional but not phenotypic T cell anergy. PMID:33974042
Levels and Characteristics of mRNAs in Spores of Firmicute Species. PMID:33972352
Knowledge bases and software support for variant interpretation in precision oncology. PMID:33971666
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20. PMID:33969602
Role of CCR2+ Myeloid Cells in Inflammation Responses Driven by Expression of a Surfactant Protein-C Mutant in the Alveolar Epithelium. PMID:33968067
Epigenetic dysregulation of immune-related pathways in cancer: bioinformatics tools and visualization. PMID:33963293
Intestinal mucosa-derived DNA methylation signatures in the penetrating intestinal mucosal lesions of Crohn's disease. PMID:33963246
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy. PMID:33956155
Screening and identification of LMNB1 and DLGAP5, two key biomarkers in gliomas. PMID:33956061
Multiple roles of H2A.Z in regulating promoter chromatin architecture in human cells. PMID:33953180
A cloud-based bioinformatic analytic infrastructure and Data Management Core for the Expanded Program on Immunization Consortium. PMID:33948273
In vivo targets of Salmonella FinO include a FinP-like small RNA controlling copy number of a cohabitating plasmid. PMID:33939833
Human methylome variation across Infinium 450K data on the Gene Expression Omnibus. PMID:33937763
Enhancing Fatty Acid Catabolism of Macrophages Within Aberrant Breast Cancer Tumor Microenvironment Can Re-establish Antitumor Function. PMID:33937269
Transcriptome Based Estrogen Related Genes Biomarkers for Diagnosis and Prognosis in Non-small Cell Lung Cancer. PMID:33936178
Leonurine-Repressed miR-18a-5p/SOCS5/JAK2/STAT3 Axis Activity Disrupts CML malignancy. PMID:33935775
SNRPC promotes hepatocellular carcinoma cell motility by inducing epithelial-mesenchymal transition. PMID:33934562
A novel five-gene signature predicts overall survival of patients with hepatocellular carcinoma. PMID:33934539
Induction of stable human FOXP3+ Tregs by a parasite-derived TGF-β mimic. PMID:33929751
Reverse Engineering of Ewing Sarcoma Regulatory Network Uncovers PAX7 and RUNX3 as Master Regulators Associated with Good Prognosis. PMID:33924679
Maternal Heat Stress Alters Expression of Genes Associated with Nutrient Transport Activity and Metabolism in Female Placentae from Mid-Gestating Pigs. PMID:33923747
Hepatic Transcriptome Profiling Reveals Lack of Acsm3 Expression in Polydactylous Rats with High-Fat Diet-Induced Hypertriglyceridemia and Visceral Fat Accumulation. PMID:33923085
Muscle Proteomic and Transcriptomic Profiling of Healthy Aging and Metabolic Syndrome in Men. PMID:33921590
Deciphering the Methylation Landscape in Breast Cancer: Diagnostic and Prognostic Biosignatures through Automated Machine Learning. PMID:33918195
Multi-Layer Picture of Neurodegenerative Diseases: Lessons from the Use of Big Data through Artificial Intelligence. PMID:33917161
Expression Patterns in Reductive Iron Assimilation and Functional Consequences during Phagocytosis of Lichtheimia corymbifera, an Emerging Cause of Mucormycosis. PMID:33916756
Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice. PMID:33916486
Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors. PMID:33914855
Increasing metadata coverage of SRA BioSample entries using deep learning-based named entity recognition. PMID:33914028
Identification of therapeutic targets of the hijacked super-enhancer complex in EVI1-rearranged leukemia. PMID:33911178
Transcriptome profiles associated with selenium-deficiency-dependent oxidative stress identify potential diagnostic and therapeutic targets in liver cancer cells. PMID:33907497
VB10, a new blood biomarker for differential diagnosis and recovery monitoring of acute viral and bacterial infections. PMID:33906069
Expression analysis of progesterone‑regulated miRNAs in cells derived from human glioblastoma. PMID:33899118
Immune Subtyping in Latent Tuberculosis. PMID:33897680
eIF4E3 forms an active eIF4F complex during stresses (eIF4FS) targeting mTOR and re-programs the translatome. PMID:33893802
Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma. PMID:33893086
BdERECTA controls vasculature patterning and phloem-xylem organization in Brachypodium distachyon. PMID:33892630
AGAP2-AS1 May Promote the Occurrence and Development of Glioblastoma by Sponging miR-9-5p: Evidence From a ceRNA Network. PMID:33889541
Identification of transcriptional subtypes in lung adenocarcinoma and squamous cell carcinoma through integrative analysis of microarray and RNA sequencing data. PMID:33888829
ARABIDOPSIS THALIANA HOMEOBOX GENE 1 controls plant architecture by locally restricting environmental responses. PMID:33888582
T cell self-reactivity during thymic development dictates the timing of positive selection. PMID:33884954
Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver. PMID:33883138
Transcriptomic alterations in malignant pleural mesothelioma cells in response to long‑term treatment with bullfrog sialic acid‑binding lectin. PMID:33880588
Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis. PMID:33879788
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells. PMID:33878299
A Case of Gene Fragmentation in Plant Mitochondria Fixed by the Selection of a Compensatory Restorer of Fertility-Like PPR Gene. PMID:33878189
Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success. PMID:33876742
Fibroblast-Specific Proteotranscriptomes Reveal Distinct Fibrotic Signatures of Human Sinoatrial Node in Nonfailing and Failing Hearts. PMID:33874740
Prognostic Signature for Lung Adenocarcinoma Patients Based on Cell-Cycle-Related Genes. PMID:33869220
In silico Design for Systems-Based Metabolic Engineering for the Bioconversion of Valuable Compounds From Industrial By-Products. PMID:33868371
Artificial intelligence to deep learning: machine intelligence approach for drug discovery. PMID:33844136
Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung. PMID:33830085
Altered Responsiveness to TGFβ and BMP and Increased CD45+ Cell Presence in Mitral Valves Are Unique Features of Ischemic Mitral Regurgitation. PMID:33827255
Fibrotic expression profile analysis reveals repurposed drugs with potential anti-fibrotic mode of action. PMID:33826640
The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine. PMID:33824333
Sequencing error profiles of Illumina sequencing instruments. PMID:33817639
Screening of Hub Genes Associated with Pulmonary Arterial Hypertension by Integrated Bioinformatic Analysis. PMID:33816621
Different Expressions of Pericardial Fluid MicroRNAs in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy and Ischemic Heart Disease Undergoing Ventricular Tachycardia Ablation. PMID:33816578
Spt4 Promotes Pol I Processivity and Transcription Elongation. PMID:33809333
Transcriptome Analyses Throughout Chili Pepper Fruit Development Reveal Novel Insights into the Domestication Process. PMID:33808668
Feature Selection Using Enhanced Particle Swarm Optimisation for Classification Models. PMID:33807806
TNMplot.com: A Web Tool for the Comparison of Gene Expression in Normal, Tumor and Metastatic Tissues. PMID:33807717
Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells. PMID:33806906
Analysis of mir-9 Expression Pattern in Rat Retina during Postnatal Development. PMID:33806574
Voluntary Wheel Running Did Not Alter Gene Expression in 5xfad Mice, but in Wild-Type Animals Exclusively after One-Day of Physical Activity. PMID:33804749
Implication of EZH2 in the Pro-Proliferative and Apoptosis-Resistant Phenotype of Pulmonary Artery Smooth Muscle Cells in PAH: A Transcriptomic and Proteomic Approach. PMID:33803922
Identification of Hub Genes and Key Pathways Associated with Anti-VEGF Resistant Glioblastoma Using Gene Expression Data Analysis. PMID:33803224
The Role of Network Science in Glioblastoma. PMID:33801334
CRISPR-Cas9-Mediated TIM3 Knockout in Human Natural Killer Cells Enhances Growth Inhibitory Effects on Human Glioma Cells. PMID:33800561
Swine Inflammation and Necrosis Syndrome Is Associated with Plasma Metabolites and Liver Transcriptome in Affected Piglets. PMID:33799520
Signal-mediated localization of Candida albicans pheromone response pathway components. PMID:33793759
Effector and regulator: Diverse functions of C. elegans C-type lectin-like domain proteins. PMID:33793670
Proteomics study on the effect of silybin on cardiomyopathy in obese mice. PMID:33785854
Six genes involved in prognosis of hepatocellular carcinoma identified by Cox hazard regression. PMID:33784984
Large-scale labeling and assessment of sex bias in publicly available expression data. PMID:33784977
Randomized Controlled Trial of the Gastrin/CCK2 Receptor Antagonist Netazepide in Patients with Barrett's Esophagus. PMID:33782049
Gene Set Knowledge Discovery with Enrichr. PMID:33780170
Benefits of Airway Androgen Receptor Expression in Human Asthma. PMID:33779531
The Burkholderia pseudomallei intracellular 'TRANSITome'. PMID:33772012
Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer's disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM functions, and iron homeostasis. PMID:33761877
Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice. PMID:33759564
Transcriptomic insight into the translational value of two murine models in human atopic dermatitis. PMID:33758305
GAUGE-Annotated Microbial Transcriptomic Data Facilitate Parallel Mining and High-Throughput Reanalysis To Form Data-Driven Hypotheses. PMID:33758032
Overexpression of CCNE1 confers a poorer prognosis in triple-negative breast cancer identified by bioinformatic analysis. PMID:33757543
GPRC5A: An emerging prognostic biomarker for predicting malignancy of Pancreatic Cancer based on bioinformatics analysis. PMID:33753999
Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. PMID:33753942
Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria. PMID:33752799
Transcriptomic analysis of feminizing somatic stem cells in the Drosophila testis reveals putative downstream effectors of the transcription factor Chinmo. PMID:33751104
Construction of competitive endogenous RNA network reveals regulatory role of long non-coding RNAs in intracranial aneurysm. PMID:33750300
Appyters: Turning Jupyter Notebooks into data-driven web apps. PMID:33748796
Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation. PMID:33747980
Comprehensive In Silico Analysis of a Novel Serum Exosome-Derived Competitive Endogenous RNA Network for Constructing a Prognostic Model for Glioblastoma. PMID:33747903
Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis. PMID:33741943
FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell. PMID:33741917
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila. PMID:33739284
Global miRNA/proteomic analyses identify miRNAs at 14q32 and 3p21, which contribute to features of chronic iron-exposed fallopian tube epithelial cells. PMID:33737539
Identification of New miRNA-mRNA Networks in the Development of Non-syndromic Cleft Lip With or Without Cleft Palate. PMID:33732700
Using Integrated Bioinformatics Analysis to Identify Abnormally Methylated Differentially Expressed Genes in Hepatocellular Carcinoma. PMID:33732011
Juxtapose: a gene-embedding approach for comparing co-expression networks. PMID:33726666
Modulation of the complex regulatory network for methionine biosynthesis in fungi. PMID:33724418
Stretch-activated ion channels identified in the touch-sensitive structures of carnivorous Droseraceae plants. PMID:33724187
Protein Biomarkers of Autism Spectrum Disorder Identified by Computational and Experimental Methods. PMID:33716802
Increased expression of MCM4 is associated with poor prognosis in patients with hepatocellular carcinoma. PMID:33708433
Correlation Between Immune Lymphoid Cells and Plasmacytoid Dendritic Cells in Human Colon Cancer. PMID:33708200
Burkholderia cenocepacia transcriptome during the early contacts with giant plasma membrane vesicles derived from live bronchial epithelial cells. PMID:33707642
Exovesicular-Shh confers Imatinib resistance by upregulating Bcl2 expression in chronic myeloid leukemia with variant chromosomes. PMID:33707419
Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6. PMID:33690173
TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. PMID:33689679
HIR V2: a human interactome resource for the biological interpretation of differentially expressed genes via gene set linkage analysis. PMID:33677507
Nerve Growth Factor Neutralization Promotes Oligodendrogenesis by Increasing miR-219a-5p Levels. PMID:33669304
Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link. PMID:33661892
CD74 is a regulator of hematopoietic stem cell maintenance. PMID:33661886
Protein interacting with C-kinase 1 is involved in epithelial-mesenchymal transformation and suppresses progress of gastric cancer. PMID:33660148
Low expression of NLRP1 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients. PMID:33658393
Fetal sex modulates placental microRNA expression, potential microRNA-mRNA interactions, and levels of amino acid transporter expression and substrates: INFAT study subpopulation analysis of n-3 LCPUFA intervention during pregnancy and associations with offspring body composition. PMID:33657992
MMP7 as a potential biomarker of colon cancer and its prognostic value by bioinformatics analysis. PMID:33655961
OXPHOS deficiency activates global adaptation pathways to maintain mitochondrial membrane potential. PMID:33655635
Cancer-Associated Fibroblasts Positively Correlate with Dedifferentiation and Aggressiveness of Thyroid Cancer. PMID:33654411
ATF3-Induced Mammary Tumors Exhibit Molecular Features of Human Basal-Like Breast Cancer. PMID:33652981
SSRE: Cell Type Detection Based on Sparse Subspace Representation and Similarity Enhancement. PMID:33647482
Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner. PMID:33640491
The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis. PMID:33637717
Computational screening of potential glioma-related genes and drugs based on analysis of GEO dataset and text mining. PMID:33635875
Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line. PMID:33634147
Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome. PMID:33633136
Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma. PMID:33629212
Identification of candidate repurposable drugs to combat COVID-19 using a signature-based approach. PMID:33627767
Dysregulated gene-associated biomarkers for Alzheimer's disease and aging. PMID:33623715
CHARTS: a web application for characterizing and comparing tumor subpopulations in publicly available single-cell RNA-seq data sets. PMID:33622236
High-throughput screening and validation of antibodies against synaptic proteins to explore opioid signaling dynamics. PMID:33619305
Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention. PMID:33619107
Inferring perturbation profiles of cancer samples. PMID:33617647
Drought-Induced Root Pressure in Sorghum bicolor. PMID:33613594
Identification of biomarkers and pathways for the SARS-CoV-2 infections that make complexities in pulmonary arterial hypertension patients. PMID:33611340
Localized EMT reprograms glial progenitors to promote spinal cord repair. PMID:33609461
The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters. PMID:33608280
Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematode Caenorhabditis remanei. PMID:33605401
Peroxisomal Multifunctional Protein 2 Deficiency Perturbs Lipid Homeostasis in the Retina and Causes Visual Dysfunction in Mice. PMID:33604342
Identification of a non-coding RNA and its putative involvement in the regulation of tetanus toxin synthesis in Clostridium tetani. PMID:33603121
Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses. PMID:33599611
Curation of over 10 000 transcriptomic studies to enable data reuse. PMID:33599246
Systems biology analysis identifies TNFRSF9 as a functional marker of tumor-infiltrating regulatory T-cell enabling clinical outcome prediction in lung cancer. PMID:33598101
Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation. PMID:33594057
Joint probabilistic modeling of single-cell multi-omic data with totalVI. PMID:33589839
Decoding the protein composition of whole nucleosomes with Nuc-MS. PMID:33589837
Concordance of Immune-Related Markers in Lymphocytes and Prefrontal Cortex in Schizophrenia. PMID:33585819
Searching for a Putative Mechanism of RIZ2 Tumor-Promoting Function in Cancer Models. PMID:33585202
Identification of key biomarkers and functional pathways in osteosarcomas with lung metastasis: Evidence from bioinformatics analysis. PMID:33578541
Guidelines for biomarker discovery in endometrium: correcting for menstrual cycle bias reveals new genes associated with uterine disorders. PMID:33576824
Identification and analysis of consensus RNA motifs binding to the genome regulator CTCF. PMID:33575587
Functional networks of co-expressed genes to explore iron homeostasis processes in the pathogenic yeast Candida glabrata. PMID:33575583
Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries. PMID:33575555
Screening and identification of hub genes in bladder cancer by bioinformatics analysis and KIF11 is a potential prognostic biomarker. PMID:33574944
Microarray Data Mining and Preliminary Bioinformatics Analysis of Hepatitis D Virus-Associated Hepatocellular Carcinoma. PMID:33564675
Knockdown of KIF15 promotes cell apoptosis by activating crosstalk of multiple pathways in ovarian cancer: bioinformatic and experimental analysis. PMID:33564360
Integrated bioinformatic analysis identifies COL4A3, COL4A4, and KCNJ1 as key biomarkers in Wilms tumor. PMID:33564352
Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. PMID:33563832
A Grad-seq View of RNA and Protein Complexes in Pseudomonas aeruginosa under Standard and Bacteriophage Predation Conditions. PMID:33563827
Family-effects in the epigenomic response of red blood cells to a challenge test in the European sea bass (Dicentrarchus labrax, L.). PMID:33563212
Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model. PMID:33563079
Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways. PMID:33561121
Association of microbiota-derived propionic acid and Alzheimer's disease; bioinformatics analysis. PMID:33553012
High-Resolution Mapping of Transcription Initiation in the Asexual Stages of Toxoplasma gondii. PMID:33553008
Transcriptome from opaque cornea of Fanconi anemia patient uncovers fibrosis and two connected players. PMID:33552906
E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates. PMID:33547048
Arabidopsis Mitochondrial Transcription Termination Factor mTERF2 Promotes Splicing of Group IIB Introns. PMID:33546419
Development and verification of an immune-related gene pairs prognostic signature in ovarian cancer. PMID:33543590
Transgenerational supplementation with eicosapentaenoic acid reduced the metabolic consequences on the whole body and skeletal muscle in mice receiving an obesogenic diet. PMID:33543364
Identification of Genes Universally Differentially Expressed in Gastric Cancer. PMID:33542925
Metabolic Versatility of Mycobacterium tuberculosis during Infection and Dormancy. PMID:33540752
Sulfatase 2 Is Associated with Steroid Resistance in Childhood Nephrotic Syndrome. PMID:33540508
GEOlimma: differential expression analysis and feature selection using pre-existing microarray data. PMID:33535967
Identification of RCC Subtype-Specific microRNAs-Meta-Analysis of High-Throughput RCC Tumor microRNA Expression Data. PMID:33535553
ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways. PMID:33534793
P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk. PMID:33532039
Identification of key miRNA-gene pairs in gastric cancer through integrated analysis of mRNA and miRNA microarray. PMID:33527022
Functional Signatures in Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis of Sex-Based Differences in Transcriptomic Studies. PMID:33526761
Acid pH Strategy Adaptation through NRG1 in Ustilago maydis. PMID:33525315
Identification of Key MicroRNAs and Mechanisms in Prostate Cancer Evolution Based on Biomarker Prioritization Model and Carcinogenic Survey. PMID:33519899
AtxA-Controlled Small RNAs of Bacillus anthracis Virulence Plasmid pXO1 Regulate Gene Expression in trans. PMID:33519762
High Throughput Sequencing of MicroRNA in Rainbow Trout Plasma, Mucus, and Surrounding Water Following Acute Stress. PMID:33519501
Role of an ancient light-harvesting protein of PSI in light absorption and photoprotection. PMID:33514722
Polycythemia Vera and Essential Thrombocythemia Patients Exhibit Unique Serum Metabolic Profiles Compared to Healthy Individuals and Secondary Thrombocytosis Patients. PMID:33513807
Identification of hub lncRNA ceRNAs in multiple sclerosis based on ceRNA mechanisms. PMID:33507382
Identification of Key Tissue-Specific, Biological Processes by Integrating Enhancer Information in Maize Gene Regulatory Networks. PMID:33505431
Identification of 37 Heterogeneous Drug Candidates for Treatment of COVID-19 via a Rational Transcriptomics-Based Drug Repurposing Approach. PMID:33504008
Genomic Adaption and Mutational Patterns in a HaCaT Subline Resistant to Alkylating Agents and Ionizing Radiation. PMID:33498964
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience. PMID:33497602
Chitosan modulates Pochonia chlamydosporia gene expression during nematode egg parasitism. PMID:33496078
AbaM Regulates Quorum Sensing, Biofilm Formation, and Virulence in Acinetobacter baumannii. PMID:33495249
Cancers in Agreement? Exploring the Cross-Talk of Cancer Metabolomic and Transcriptomic Landscapes Using Publicly Available Data. PMID:33494351
COL1A1 Is a Potential Prognostic Biomarker and Correlated with Immune Infiltration in Mesothelioma. PMID:33490271
Identification of IL10RA by Weighted Correlation Network Analysis and in vitro Validation of Its Association With Prognosis of Metastatic Melanoma. PMID:33490091
Challenge of Bovine Foot Skin Fibroblasts With Digital Dermatitis Treponemes Identifies Distinct Pathogenic Mechanisms. PMID:33489929
A meta-analysis of comorbidities in COVID-19: Which diseases increase the susceptibility of SARS-CoV-2 infection? PMID:33486379
Mining influential genes based on deep learning. PMID:33482718
CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells. PMID:33471607
Enrichment and Correlation Analysis of Serum miRNAs in Comorbidity Between Arnold-Chiari and Tourette Syndrome Contribute to Clarify Their Molecular Bases. PMID:33469418
Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial. PMID:33463067
DNA methylome signatures of prenatal exposure to synthetic glucocorticoids in hippocampus and peripheral whole blood of female guinea pigs in early life. PMID:33462183
Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer. PMID:33456569
Computational methods for the prediction of chromatin interaction and organization using sequence and epigenomic profiles. PMID:33454752
Systematic analysis of differential rhythmic liver gene expression mediated by the circadian clock and feeding rhythms. PMID:33452134
Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice. PMID:33450231
The pioneer and differentiation factor FOXA2 is a key driver of yolk-sac tumour formation and a new biomarker for paediatric and adult yolk-sac tumours. PMID:33448076
SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β cells. PMID:33446570
JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions. PMID:33445503
Endogenous membrane stress induces T6SS activity in Pseudomonas aeruginosa. PMID:33443205
Prognostic significance of KRT19 in Lung Squamous Cancer. PMID:33442422
AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer's drug discovery. PMID:33441136
Streamlining data-intensive biology with workflow systems. PMID:33438730
Prognosis Prediction for Colorectal Cancer Patients: A Risk Score Based on The Metabolic-Related Genes. PMID:33437216
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice. PMID:33436815
STIM1 Mediates Calcium-Dependent Epigenetic Reprogramming in Pancreatic Cancer. PMID:33436389
Exome-wide evaluation of rare coding variants using electronic health records identifies new gene-phenotype associations. PMID:33432171
Droplet-based mRNA sequencing of fixed and permeabilized cells by CLInt-seq allows for antigen-specific TCR cloning. PMID:33431692
Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys. PMID:33431511
A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions. PMID:33431024
Whole Transcription Profile of Responders to Anti-TNF Drugs in Pediatric Inflammatory Bowel Disease. PMID:33429950
FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs. PMID:33420223
Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling. PMID:33418509
Metabolic reprogramming of the myeloid lineage by Schistosoma mansoni infection persists independently of antigen exposure. PMID:33417618
Transcriptomic analysis identifies organ-specific metastasis genes and pathways across different primary sites. PMID:33413400
Biomechanical Forces Regulate Gene Transcription During Stretch-Mediated Growth of Mammalian Neurons. PMID:33408609
STRA8 induces transcriptional changes in germ cells during spermatogonial development. PMID:33400349
Integrated molecular characterisation of the MAPK pathways in human cancers reveals pharmacologically vulnerable mutations and gene dependencies. PMID:33398072
microRNA Sequencing of CD34+ Sorted Adipose Stem Cells Undergoing Endotheliogenesis. PMID:33397204
Personalized beyond Precision: Designing Unbiased Gold Standards to Improve Single-Subject Studies of Personal Genome Dynamics from Gene Products. PMID:33396440
Pan-Cancer Molecular Patterns and Biological Implications Associated with a Tumor-Specific Molecular Signature. PMID:33396205
Specific MiRNAs in naïve T cells associated with Hepatitis C Virus-induced Hepatocellular Carcinoma. PMID:33391397
High-Pressure-Sprayed Double Stranded RNA Does Not Induce RNA Interference of a Reporter Gene. PMID:33391294
Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model. PMID:33387578
High Levels of Prebiotic Resistant Starch in Diet Modulate a Specific Pattern of miRNAs Expression Profile Associated to a Better Overall Survival in Pancreatic Cancer. PMID:33383727
HeartBioPortal2.0: new developments and updates for genetic ancestry and cardiometabolic quantitative traits in diverse human populations. PMID:33382884
Epstein-Barr virus LMP1 manipulates the content and functions of extracellular vesicles to enhance metastatic potential of recipient cells. PMID:33382850
Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure. PMID:33382739
Adversarial deconfounding autoencoder for learning robust gene expression embeddings. PMID:33381842
A Multi-Pronged Computational Pipeline for Prioritizing Drug Target Strategies for Latent Tuberculosis. PMID:33381491
USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells. PMID:33378683
Identifying biomolecules and constructing a prognostic risk prediction model for recurrence in osteosarcoma. PMID:33376666
Effect of let-7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinoma. PMID:33376529
Transcriptional profiling of the stringent response mutant strain E. coli SR reveals enhanced robustness to large-scale conditions. PMID:33369128
An Educational Bioinformatics Project to Improve Genome Annotation. PMID:33365016
Development and Validation of an Immune-Related Gene Pair Signature in Skin Cutaneous Melanoma. PMID:33364806
MiRNA-Mediated Subpathway Identification and Network Module Analysis to Reveal Prognostic Markers in Human Pancreatic Cancer. PMID:33362865
Acyl-CoA Thioesterase 8 and 11 as Novel Biomarkers for Clear Cell Renal Cell Carcinoma. PMID:33362855
Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit. PMID:33357414
MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment. PMID:33352466
An Integrated Analysis of miRNA and Gene Expression Changes in Response to an Obesogenic Diet to Explore the Impact of Transgenerational Supplementation with Omega 3 Fatty Acids. PMID:33348802
Dynamics of transcriptional and post-transcriptional regulation. PMID:33348360
Denoising Autoencoder, A Deep Learning Algorithm, Aids the Identification of A Novel Molecular Signature of Lung Adenocarcinoma. PMID:33346087
Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring's brain and behavior. PMID:33344732
Benchmarking Computational Doublet-Detection Methods for Single-Cell RNA Sequencing Data. PMID:33338399
MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle. PMID:33338203
Molecular patterns of isolated tubulitis differ from tubulitis with interstitial inflammation in early indication biopsies of kidney allografts. PMID:33335257
The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction. PMID:33332560
Riproximin Exhibits Diversity in Sugar Binding, and Modulates some Metastasis-Related Proteins with Lectin like Properties in Pancreatic Ductal Adenocarcinoma. PMID:33328982
Aortic Gene Expression Profiles Show How ApoA-I Levels Modulate Inflammation, Lysosomal Activity, and Sphingolipid Metabolism in Murine Atherosclerosis. PMID:33327742
Integrated Multichip Analysis Identifies Potential Key Genes in the Pathogenesis of Nonalcoholic Steatohepatitis. PMID:33324350
Cellular and Molecular Response of Macrophages THP-1 during Co-Culture with Inactive Trichophyton rubrum Conidia. PMID:33322794
Tensor-Decomposition-Based Unsupervised Feature Extraction Applied to Prostate Cancer Multiomics Data. PMID:33322492
Toll-Like Receptor 7 Is Required for Lacrimal Gland Autoimmunity and Type 1 Diabetes Development in Male Nonobese Diabetic Mice. PMID:33322152
Revealing Epigenetic Factors of circRNA Expression by Machine Learning in Various Cellular Contexts. PMID:33319172
Endometriosis Is Associated with a Significant Increase in hTERC and Altered Telomere/Telomerase Associated Genes in the Eutopic Endometrium, an Ex-Vivo and In Silico Study. PMID:33317189
Harmine and Piperlongumine Revert TRIB2-Mediated Drug Resistance. PMID:33316942
Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer. PMID:33313947
A bioinformatics analysis on the potential role of ACE2 in cardiac impairment of patients with coronavirus disease 2019. PMID:33313148
Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis. PMID:33310759
Run or Die in the Evolution of New MicroRNAs-Testing the Red Queen Hypothesis on De Novo New Genes. PMID:33306129
Coagulopathy in Malnourished Mice Is Sexually Dimorphic and Regulated by Nutrient-Sensing Nuclear Receptors. PMID:33305154
PDmethDB: A curated Parkinson's disease associated methylation information database. PMID:33304468
Genetic interaction mapping informs integrative structure determination of protein complexes. PMID:33303586
Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis. PMID:33300287
Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes. PMID:33298456
Transcriptome Remodeling in Gradual Development of Inverse Resistance between Paclitaxel and Cisplatin in Ovarian Cancer Cells. PMID:33287223
Identification of candidate biomarkers correlated with the pathogenesis and prognosis of breast cancer via integrated bioinformatics analysis. PMID:33285689
Differences in key genes in human alveolar macrophages between phenotypically normal smokers and nonsmokers: diagnostic and prognostic value in lung cancer. PMID:33284895
Next generation sequencing of SARS-CoV-2 genomes: challenges, applications and opportunities. PMID:33279989
A review of COVID-19 biomarkers and drug targets: resources and tools. PMID:33279954
Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma. PMID:33277569
MethHC 2.0: information repository of DNA methylation and gene expression in human cancer. PMID:33270889
The microRNA miR-29c-5p inhibits cell proliferation and migration by targeting TMEM98 in head and neck carcinoma. PMID:33257597
An Improved, Assay Platform Agnostic, Absolute Single Sample Breast Cancer Subtype Classifier. PMID:33255759
Manganese Depletion Leads to Multisystem Changes in the Transcriptome of the Opportunistic Pathogen Streptococcus sanguinis. PMID:33250881
PAGER-CoV: a comprehensive collection of pathways, annotated gene-lists and gene signatures for coronavirus disease studies. PMID:33245774
Spontaneous intake of essential oils after a negative postnatal experience has long-term effects on blood transcriptome in chickens. PMID:33244117
Bioinformatics Analysis Identifies a Novel Role of GINS1 Gene in Colorectal Cancer. PMID:33235499
Investigation of drugs affecting hypertension in bevacizumab-treated patients and examination of the impact on the therapeutic effect. PMID:33231381
Active Transposition of Insertion Sequences by Oxidative Stress in Deinococcus geothermalis. PMID:33224109
FHOD formin and SRF promote post-embryonic striated muscle growth through separate pathways in C. elegans. PMID:33221314
Transcriptome profiling of laser-captured crown root primordia reveals new pathways activated during early stages of crown root formation in rice. PMID:33211715
Extracellular traps released by antimicrobial TH17 cells contribute to host defense. PMID:33211671
Biophysical and X-ray structural studies of the (GGGTT)3GGG G-quadruplex in complex with N-methyl mesoporphyrin IX. PMID:33206666
Patrolling monocytes inhibit osteosarcoma metastasis to the lung. PMID:33203789
Sarcolipin Exhibits Abundant RNA Transcription and Minimal Protein Expression in Horse Gluteal Muscle. PMID:33202832
Bile Ductal Transcriptome Identifies Key Pathways and Hub Genes in Clonorchis sinensis-Infected Sprague-Dawley Rats. PMID:33202503
ACVR2B antagonism as a countermeasure to multi-organ perturbations in metastatic colorectal cancer cachexia. PMID:33200567
Mutation bias within oncogene families is related to proliferation-specific codon usage. PMID:33199641
iCLIP analysis of RNA substrates of the archaeal exosome. PMID:33198623
Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids. PMID:33195205
A Novel Signature of 23 Immunity-Related Gene Pairs Is Prognostic of Cutaneous Melanoma. PMID:33193373
Data mining combined with experiments to validate CEP55 as a prognostic biomarker in colorectal cancer. PMID:33190424
Interleukin-6 (IL-6) deficiency enhances intramembranous osteogenesis following stress fracture in mice. PMID:33181349
Distinct regional ontogeny and activation of tumor associated macrophages in human glioblastoma. PMID:33177572
Co‑expression network analysis identified specific miRNAs and genes in association with slow‑transit constipation. PMID:33174045
Systematic Analysis of Protein-Protein and Gene-Environment Interactions to Decipher the Cognitive Mechanisms of Autism Spectrum Disorder. PMID:33165687
A single-cell atlas and lineage analysis of the adult Drosophila ovary. PMID:33159074
Maximizing the reusability of gene expression data by predicting missing metadata. PMID:33156882
Inhibition of inflammatory signaling in Pax5 mutant cells mitigates B-cell leukemogenesis. PMID:33154497
Unsupervised and supervised learning with neural network for human transcriptome analysis and cancer diagnosis. PMID:33154423
Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution. PMID:33154001
The RSC (Remodels the Structure of Chromatin) complex of Candida albicans shows compositional divergence with distinct roles in regulating pathogenic traits. PMID:33151931
Investigation of the potential regulator proteins associated with the expression of major surface protein and dentilisin in Treponema denticola. PMID:33149843
Integrative Analysis of miRNAs Identifies Clinically Relevant Epithelial and Stromal Subtypes of Head and Neck Squamous Cell Carcinoma. PMID:33148669
Expression of EMT-Related Genes in Hybrid E/M Colorectal Cancer Cells Determines Fibroblast Activation and Collagen Remodeling. PMID:33143259
The Antiviral Small-Interfering RNA Pathway Induces Zika Virus Resistance in Transgenic Aedes aegypti. PMID:33142991
Utilizing PacBio Iso-Seq for Novel Transcript and Gene Discovery of Abiotic Stress Responses in Oryza sativa L. PMID:33142722
Whole egg consumption increases gene expression within the glutathione pathway in the liver of Zucker Diabetic Fatty rats. PMID:33141822
Correcting for experiment-specific variability in expression compendia can remove underlying signals. PMID:33140829
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis. PMID:33140449
Functional module detection through integration of single-cell RNA sequencing data with protein-protein interaction networks. PMID:33138772
A Systems Biology Approach to Identifying a Master Regulator That Can Transform the Fast Growing Cellular State to a Slowly Growing One in Early Colorectal Cancer Development Model. PMID:33133158
Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning. PMID:33133152
SINEUP long non-coding RNA acts via PTBP1 and HNRNPK to promote translational initiation assemblies. PMID:33130894
The birth of a bacterial tRNA gene by large-scale, tandem duplication events. PMID:33124983
Targeting 14-3-3ζ Overcomes Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Lung Adenocarcinoma via BMP2/Smad/ID1 Signaling. PMID:33123465
Changes in Northern Elephant Seal Skeletal Muscle Following Thirty Days of Fasting and Reduced Activity. PMID:33123026
A long noncoding RNA antisense to ICAM-1 is involved in allergic asthma associated hyperreactive response of airway epithelial cells. PMID:33122732
A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells. PMID:33122441
Screening and identification of key genes and pathways in metastatic uveal melanoma based on gene expression using bioinformatic analysis. PMID:33120861
Enzymatic Dissociation Induces Transcriptional and Proteotype Bias in Brain Cell Populations. PMID:33114694
Transcriptomic and Phenotypic Analyses of the Sigma B-Dependent Characteristics and the Synergism between Sigma B and Sigma L in Listeria monocytogenes EGD-e. PMID:33114171
Preparation of Multi-omics Grade Extracellular Vesicles by Density-Based Fractionation of Urine. PMID:33111109
Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia. PMID:33108352
ROS networks: designs, aging, Parkinson's disease and precision therapies. PMID:33106503
Genome-wide identification of accessible chromatin regions in bumblebee by ATAC-seq. PMID:33106500
Response of Pseudomonas aeruginosa to the Innate Immune System-Derived Oxidants Hypochlorous Acid and Hypothiocyanous Acid. PMID:33106346
Integrated Microarray to Identify the Hub miRNAs and Constructed miRNA-mRNA Network in Neuroblastoma Via Bioinformatics Analysis. PMID:33104965
Identification of a Twelve-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival for Medulloblastoma. PMID:33101383
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells. PMID:33098807
Meta-analysis of Transcriptomic Data Reveals Pathophysiological Modules Involved with Atrial Fibrillation. PMID:33095430
Systems analysis of avascular necrosis of femoral head using integrative data analysis and literature mining delineates pathways associated with disease. PMID:33093559
A Semi-Automated Workflow for FAIR Maturity Indicators in the Life Sciences. PMID:33092028
Identification of a nomogram based on an 8-lncRNA signature as a novel diagnostic biomarker for head and neck squamous cell carcinoma. PMID:33091878
Tumor infiltrating immune cells (TIICs) as a biomarker for prognosis benefits in patients with osteosarcoma. PMID:33087099
Improved personalized survival prediction of patients with diffuse large B-cell Lymphoma using gene expression profiling. PMID:33087075
Comparative transcriptomics reveals hidden issues in the plant response to arthropod herbivores. PMID:33085192
Common gene signatures and key pathways in hypopharyngeal and esophageal squamous cell carcinoma: Evidence from bioinformatic analysis. PMID:33080677
Predicted functional interactome of Caenorhabditis elegans and a web tool for the functional interpretation of differentially expressed genes. PMID:33076954
A flexible, interpretable, and accurate approach for imputing the expression of unmeasured genes. PMID:33074331
Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model. PMID:33072095
Transcriptome analysis of Brucella abortus S19∆per immunized mouse spleen revealed activation of MHC-I and MHC-II pathways. PMID:33062939
Whole transcriptomic network analysis using Co-expression Differential Network Analysis (CoDiNA). PMID:33057419
Activation of the CARD8 Inflammasome Requires a Disordered Region. PMID:33053349
Identification of potential key genes and miRNAs involved in Hepatoblastoma pathogenesis and prognosis. PMID:33051830
Maintenance of Cell Fate by the Polycomb Group Gene Sex Combs Extra Enables a Partial Epithelial Mesenchymal Transition in Drosophila. PMID:33051260
Therapeutic Opportunities for Intestinal Angioectasia- Targeting PPARγ and Oxidative Stress. PMID:33048460
Machine learning approach to integrated endometrial transcriptomic datasets reveals biomarkers predicting uterine receptivity in cattle at seven days after estrous. PMID:33046742
Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes. PMID:33045922
Silencing KIF18B enhances radiosensitivity: identification of a promising therapeutic target in sarcoma. PMID:33038765
Bioinformatic Identification of Potential Hub Genes in Muscle-Invasive Bladder Urothelial Carcinoma. PMID:33035117
Joint learning of multiple gene networks from single-cell gene expression data. PMID:33033579
Olfactory Stimulation Regulates the Birth of Neurons That Express Specific Odorant Receptors. PMID:33027656
Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice. PMID:33024996
Network-based identification genetic effect of SARS-CoV-2 infections to Idiopathic pulmonary fibrosis (IPF) patients. PMID:33024988
Survival Strategies of Pathogenic Candida Species in Human Blood Show Independent and Specific Adaptations. PMID:33024045
H. pylori modulates DC functions via T4SS/TNFα/p38-dependent SOCS3 expression. PMID:33023610
Long-Term m5C Methylome Dynamics Parallel Phenotypic Adaptation in the Cyanobacterium Trichodesmium. PMID:33022053
Curated gene expression dataset of differentiating 3T3-L1 adipocytes under pharmacological and genetic perturbations. PMID:33016192
Investigating genetic drivers of dermatomyositis pathogenesis using meta-analysis. PMID:33015383
Screening and Identification of Key Biomarkers in Acquired Lapatinib-Resistant Breast Cancer. PMID:33013420
Database: web application for visualization of the cumulated RNAseq data against the salicylic acid (SA) and methyl jasmonate (MeJA) treatment of Arabidopsis thaliana. PMID:33008298
Reanalysis of Gene Expression Profiles of CD4+ T Cells Treated with HIV-1 Latency Reversal Agents. PMID:33007800
Integrative Analysis of Membrane Proteome and MicroRNA Reveals Novel Lung Cancer Metastasis Biomarkers. PMID:33005184
Transcriptional and Metabolic Profiling of Potato Plants Expressing a Plastid-Targeted Electron Shuttle Reveal Modulation of Genes Associated to Drought Tolerance by Chloroplast Redox Poise. PMID:33003500
The Cu(II) Reductase RclA Protects Escherichia coli against the Combination of Hypochlorous Acid and Intracellular Copper. PMID:32994322
Sex Steroids Induce Membrane Stress Responses and Virulence Properties in Pseudomonas aeruginosa. PMID:32994320
Reconstruction of lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveals functional lncRNAs in skin cutaneous melanoma. PMID:32993558
Inducible Deletion of YAP and TAZ in Adult Mouse Smooth Muscle Causes Rapid and Lethal Colonic Pseudo-Obstruction. PMID:32992050
Analysis of wild tomato introgression lines elucidates the genetic basis of transcriptome and metabolome variation underlying fruit traits and pathogen response. PMID:32989321
Tissue-specific usage of transposable element-derived promoters in mouse development. PMID:32988383
Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence. PMID:32987276
A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer. PMID:32984053
STAB: a spatio-temporal cell atlas of the human brain. PMID:32976581
Amphotericin B Specifically Induces the Two-Component System LnrJK: Development of a Novel Whole-Cell Biosensor for the Detection of Amphotericin-Like Polyenes. PMID:32973732
Landscape of Genome-Wide DNA Methylation of Colorectal Cancer Metastasis. PMID:32971738
MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly. PMID:32969791
Genome Wide Analysis Points towards Subtype-Specific Diseases in Different Genetic Forms of Amyotrophic Lateral Sclerosis. PMID:32967368
Mining genetic and transcriptomic data using machine learning approaches in Parkinson's disease. PMID:32964109
Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs. PMID:32961143
Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory diseases. PMID:32958661
Human G-MDSCs are neutrophils at distinct maturation stages promoting tumor growth in breast cancer. PMID:32958605
High dimensional model representation of log likelihood ratio: binary classification with SNP data. PMID:32957998
Integrated Bioinformatics analysis and clinical validation reveals that high expression of mucin 1 in intrahepatic cholangiocarcinoma predicts recurrence after curative resection. PMID:32952640
Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta. PMID:32949999
Cancer gene expression profiles associated with clinical outcomes to chemotherapy treatments. PMID:32948183
A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer. PMID:32947124
Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. PMID:32940601
Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells. PMID:32940375
Analyzing Gene Expression Profiles from Ataxia and Spasticity Phenotypes to Reveal Spastic Ataxia Related Pathways. PMID:32937819
Identification, Validation, and Functional Annotations of Genome-Wide Profile Variation between Melanocytic Nevus and Malignant Melanoma. PMID:32934956
Sterol regulatory element-binding protein Sre1 regulates carotenogenesis in the red yeast Xanthophyllomyces dendrorhous. PMID:32933952
The brlA Gene Deletion Reveals That Patulin Biosynthesis Is Not Related to Conidiation in Penicillium expansum. PMID:32932988
A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans. PMID:32930709
The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA. PMID:32926445
Are Antisense Proteins in Prokaryotes Functional? PMID:32923454
Identification and validation of novel metastasis-related signatures of clear cell renal cell carcinoma using gene expression databases. PMID:32913492
A gene prioritization method based on a swine multi-omics knowledgebase and a deep learning model. PMID:32913254
An intact gut microbiome protects genetically predisposed mice against leukemia. PMID:32911536
Network Pharmacology to Uncover the Biological Basis of Spleen Qi Deficiency Syndrome and Herbal Treatment. PMID:32908629
TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. PMID:32908304
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia. PMID:32908143
Integrated PPI- and WGCNA-Retrieval of Hub Gene Signatures Shared Between Barrett's Esophagus and Esophageal Adenocarcinoma. PMID:32903837
Nrf2 contributes to the weight gain of mice during space travel. PMID:32901092
The Utility of Resolving Asthma Molecular Signatures Using Tissue-Specific Transcriptome Data. PMID:32900903
Serial Passage of Cryptococcus neoformans in Galleria mellonella Results in Increased Capsule and Intracellular Replication in Hemocytes, but Not Increased Resistance to Hydrogen Peroxide. PMID:32899539
RnhP is a plasmid-borne RNase HI that contributes to genome maintenance in the ancestral strain Bacillus subtilis NCIB 3610. PMID:32896031
Bioinformatic analysis reveals hub genes and pathways that promote melanoma metastasis. PMID:32894090
FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer. PMID:32888433
Identification of circular RNA hsa_circ_0044556 and its effect on the progression of colorectal cancer. PMID:32884449
Integrative Analysis of MAPK14 as a Potential Biomarker for Cardioembolic Stroke. PMID:32879891
Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis. PMID:32875282
Polar Infection of Echovirus-30 Causes Differential Barrier Affection and Gene Regulation at the Blood-Cerebrospinal Fluid Barrier. PMID:32872518
Dysregulated circulating SOCS3 and haptoglobin expression associated with stable coronary artery disease and acute coronary syndrome: An integrated study based on bioinformatics analysis and case-control validation. PMID:32870172
Dorsoventral inversion of the air-filled organ (lungs, gas bladder) in vertebrates: RNAsequencing of laser capture microdissected embryonic tissue. PMID:32864827
Comprehensive analysis of key genes associated with ceRNA networks in nasopharyngeal carcinoma based on bioinformatics analysis. PMID:32863767
Comparative Transcriptomic Analysis of Cerebral Organoids and Cortical Neuron Cultures Derived from Human Induced Pluripotent Stem Cells. PMID:32862797
Machine learning discriminates a movement disorder in a zebrafish model of Parkinson's disease. PMID:32859696
Identification of key differentially expressed mRNAs and microRNAs in non-small cell lung cancer using bioinformatics analysis. PMID:32855723
Comparative Analysis of the Development of Acquired Radioresistance in Canine and Human Mammary Cancer Cell Lines. PMID:32851022
Systematic Evaluation of the Diagnostic and Prognostic Significance of Competitive Endogenous RNA Networks in Prostate Cancer. PMID:32849794
Target Analysis and Mechanism of Podophyllotoxin in the Treatment of Triple-Negative Breast Cancer. PMID:32848800
Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity. PMID:32847508
Whole transcriptome analysis of bovine mammary progenitor cells by P-Cadherin enrichment as a marker in the mammary cell hierarchy. PMID:32843665
An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer. PMID:32842712
SARS-CoV-2 infection dynamics in lungs of African green monkeys. PMID:32839775
Cytomegalovirus infection elicits a conserved chemokine response from human and guinea pig amnion cells. PMID:32838950
Microarray Normalization Revisited for Reproducible Breast Cancer Biomarkers. PMID:32832541
Analyzing the lncRNA, miRNA, and mRNA-associated ceRNA networks to reveal potential prognostic biomarkers for glioblastoma multiforme. PMID:32821246
Cancer-Derived Transforming Growth Factor-β Modulates Tumor-Associated Macrophages in Ampullary Cancer. PMID:32821120
Xylem systems genetics analysis reveals a key regulator of lignin biosynthesis in Populus deltoides. PMID:32817237
Grad-seq shines light on unrecognized RNA and protein complexes in the model bacterium Escherichia coli. PMID:32813020
Human Tregs at the materno-fetal interface show site-specific adaptation reminiscent of tumor Tregs. PMID:32809975
Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells. PMID:32806648
Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection. PMID:32802507
The lysine demethylase KDM4A controls the cell-cycle expression of replicative canonical histone genes. PMID:32798738
Integrated Framework of the Immune-Defense Transcriptional Signatures in the Arabidopsis Shoot Apical Meristem. PMID:32796535
Transcriptome profiles acquired during cell expansion and licensing validate mesenchymal stromal cell lineage genes. PMID:32795342
Identification and Validation of Key Genes Associated With Systemic Sclerosis-Related Pulmonary Hypertension. PMID:32793290
Cysteine and Methionine Biosynthetic Enzymes Have Distinct Effects on Seed Nutritional Quality and on Molecular Phenotypes Associated With Accumulation of a Methionine-Rich Seed Storage Protein in Rice. PMID:32793268
Deregulated High Affinity Copper Transport Alters Iron Homeostasis in Arabidopsis. PMID:32793263
Elucidating the fundamental fibrotic processes driving abdominal adhesion formation. PMID:32792541
Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration. PMID:32791514
Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets. PMID:32790767
Gene Expression Network Analysis of Precursor Lesions in Familial Pancreatic Cancer. PMID:32783019
The oxytocin receptor signalling system and breast cancer: a critical review. PMID:32782397
Identification of common and divergent gene expression signatures in patients with venous and arterial thrombosis using data from public repositories. PMID:32780732
Identification of Players Controlling Meristem Arrest Downstream of the FRUITFULL-APETALA2 Pathway. PMID:32778534
Computational Identification of Tumor Suppressor Genes Based on Gene Expression Profiles in Normal and Cancerous Gastrointestinal Tissues. PMID:32774369
Molecular Signatures and Networks of Cardiomyocyte Differentiation in Humans and Mice. PMID:32769060
Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard. PMID:32767459
Bioinformatics analysis shows that TOP2A functions as a key candidate gene in the progression of cervical cancer. PMID:32765860
Systems Biology Will Direct Vascular-Targeted Therapy for Obesity. PMID:32760294
Characterization of peripheral blood mononuclear cells gene expression profiles of pediatric Staphylococcus aureus persistent and non-carriers using a targeted assay. PMID:32758644
Eight immune-related genes predict survival outcomes and immune characteristics in breast cancer. PMID:32756008
Escherichia coli Has a Unique Transcriptional Program in Long-Term Stationary Phase Allowing Identification of Genes Important for Survival. PMID:32753505
An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease. PMID:32753478
Aberrant methylation and microRNA-target regulation are associated with downregulated NEURL1B: a diagnostic and prognostic target in colon cancer. PMID:32742189
Dynamical gene regulatory networks are tuned by transcriptional autoregulation with microRNA feedback. PMID:32737375
Absence of Plekhg5 Results in Myelin Infoldings Corresponding to an Impaired Schwann Cell Autophagy, and a Reduced T-Cell Infiltration Into Peripheral Nerves. PMID:32733205
The effect of compound kushen injection on cancer cells: Integrated identification of candidate molecular mechanisms. PMID:32730293
Human Nasal Turbinate Tissues in Organ Culture as a Model for Human Cytomegalovirus Infection at the Mucosal Entry Site. PMID:32727881
Time-Dependent miRNA Profile during Septic Acute Kidney Injury in Mice. PMID:32727087
Protamine-2 Deficiency Initiates a Reactive Oxygen Species (ROS)-Mediated Destruction Cascade during Epididymal Sperm Maturation in Mice. PMID:32727081
Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis. PMID:32719743
Inflammatory state of lymphatic vessels and miRNA profiles associated with relapse in ovarian cancer patients. PMID:32716937
Preeclamptic placentae release factors that damage neurons: implications for foetal programming of disease. PMID:32714596
Study on the Selection of the Targets of Esophageal Carcinoma and Interventions of Ginsenosides Based on Network Pharmacology and Bioinformatics. PMID:32714406
Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis. PMID:32714115
Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells. PMID:32709741
Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function. PMID:32709255
Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy. PMID:32708981
Exploring Drug Treatment Patterns Based on the Action of Drug and Multilayer Network Model. PMID:32708644
Cell-Type Specificity of Genomic Imprinting in Cerebral Cortex. PMID:32707083
Membrane budding is a major mechanism of in vivo platelet biogenesis. PMID:32706855
A chemical biology approach to identifying molecular pathways associated with aging. PMID:32705410
Cross‑validation of genes potentially associated with neoadjuvant chemotherapy and platinum‑based chemoresistance in epithelial ovarian carcinoma. PMID:32705213
EGF-mediated reduced miR-92a-1-5p controls HTR-8/SVneo cell invasion through activation of MAPK8 and FAS which in turn increase MMP-2/-9 expression. PMID:32703964
Identification of key genes in calcific aortic valve disease by integrated bioinformatics analysis. PMID:32702920
Identification of new drug treatments to combat COVID19: A signature-based approach using iLINCS. PMID:32702077
Identifying the novel key genes in renal cell carcinoma by bioinformatics analysis and cell experiments. PMID:32699530
Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers. PMID:32698000
An NMR-based approach reveals the core structure of the functional domain of SINEUP lncRNAs. PMID:32697302
Unique molecular signatures of microRNAs in ocular fluids and plasma in diabetic retinopathy. PMID:32692745
Developmental function and state transitions of a gene expression oscillator in Caenorhabditis elegans. PMID:32687264
Deep Proteomic Deconvolution of Interferons and HBV Transfection Effects on a Hepatoblastoma Cell Line. PMID:32685848
NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli. PMID:32683448
PfMAP-2 is essential for male gametogenesis in the malaria parasite Plasmodium falciparum. PMID:32681115
Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice. PMID:32681022
TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity. PMID:32680955
Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia. PMID:32680723
Molecular and clinical characterization of PARP9 in gliomas: A potential immunotherapeutic target. PMID:32678519
Gene expression profiling identifies the role of Zac1 in cervical cancer metastasis. PMID:32678267
Chemical Priming by Isothiocyanates Protects Against Intoxication by Products of the Mustard Oil Bomb. PMID:32676087
Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium. PMID:32668249
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation. PMID:32667968
Bioinformatics-based analysis of the lncRNA-miRNA-mRNA and TF regulatory networks reveals functional genes in esophageal squamous cell carcinoma. PMID:32662828
Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing. PMID:32661314
The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis. PMID:32660590
Extracellular vesicles from Heligmosomoides bakeri and Trichuris muris contain distinct microRNA families and small RNAs that could underpin different functions in the host. PMID:32659276
Global discovery of bacterial RNA-binding proteins by RNase-sensitive gradient profiles reports a new FinO domain protein. PMID:32646969
VviERF6Ls: an expanded clade in Vitis responds transcriptionally to abiotic and biotic stresses and berry development. PMID:32646368
Identification of key genes for esophageal squamous cell carcinoma via integrated bioinformatics analysis and experimental confirmation. PMID:32642240
Microinjection induces changes in the transcriptome of bovine oocytes. PMID:32641751
RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism. PMID:32641587
Characterization of cell-free breast cancer patient-derived scaffolds using liquid chromatography-mass spectrometry/mass spectrometry data and RNA sequencing data. PMID:32637480
Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules. PMID:32636252
Machine Learning-Based Ensemble Recursive Feature Selection of Circulating miRNAs for Cancer Tumor Classification. PMID:32635415
A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program. PMID:32634384
Screening and identification of key gene in sepsis development: Evidence from bioinformatics analysis. PMID:32629654
Array Analysis Manager-An automated DNA microarray analysis tool simplifying microarray data filtering, bias recognition, normalization, and expression analysis. PMID:32624831
Rapid activation of distinct members of multigene families in Plasmodium spp. PMID:32620892
Quiescent stem cell marker genes in glioma gene networks are sufficient to distinguish between normal and glioblastoma (GBM) samples. PMID:32616845
Changes in gene expression in potato meristems treated with the sprout suppressor 1,4-dimethylnaphthalene are dependent on tuber age and dormancy status. PMID:32614863
cnd-1/NeuroD1 Functions with the Homeobox Gene ceh-5/Vax2 and Hox Gene ceh-13/labial To Specify Aspects of RME and DD Neuron Fate in Caenorhabditis elegans. PMID:32601060
Methylation data imputation performances under different representations and missingness patterns. PMID:32600298
Big behavior: challenges and opportunities in a new era of deep behavior profiling. PMID:32599604
PRC2-mediated H3K27me3 modulates shoot iron homeostasis in Arabidopsis thaliana. PMID:32594838
Hub genes and key pathways of traumatic brain injury: bioinformatics analysis and in vivo validation. PMID:32594047
Tryptophanyl-tRNA Synthetase, a Novel Damage-Induced Cytokine, Significantly Increases the Therapeutic Effects of Endometrial Stem Cells. PMID:32592690
An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila. PMID:32592682
Adipose tissue in health and disease through the lens of its building blocks. PMID:32591560
Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis. PMID:32587798
Minichromosome maintenance 6 complex component identified by bioinformatics analysis and experimental validation in esophageal squamous cell carcinoma. PMID:32583000
The Genetic Regulation of Alternative Splicing in Populus deltoides. PMID:32582229
Short-Term Magnesium Deficiency Triggers Nutrient Retranslocation in Arabidopsis thaliana. PMID:32582226
Adjuvanting Allergen Extracts for Sublingual Immunotherapy: Calcitriol Downregulates CXCL8 Production in Primary Sublingual Epithelial Cells. PMID:32582164
Deciphering the Novel Target Genes Involved in the Epigenetics of Hepatocellular Carcinoma Using Graph Theory Approach. PMID:32581643
Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia. PMID:32581241
Construction, analysis and validation of co-expression network to understand stress adaptation in Deinococcus radiodurans R1. PMID:32579573
Signature genes associated with immunological non-responsiveness to anti-retroviral therapy in HIV-1 subtype-c infection. PMID:32579550
The Tomato DELLA Protein PROCERA Promotes Abscisic Acid Responses in Guard Cells by Upregulating an Abscisic Acid Transporter. PMID:32576645
A circular RNA map for human induced pluripotent stem cells of foetal origin. PMID:32574961
Genome-wide transcriptome architecture in a mouse model of Gulf War Illness. PMID:32574576
Genome-wide Enrichment of De Novo Coding Mutations in Orofacial Cleft Trios. PMID:32574564
Infection cushions of Fusarium graminearum are fungal arsenals for wheat infection. PMID:32573086
Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development. PMID:32571908
Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor. PMID:32571799
Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model. PMID:32571478
Construction and analysis of a lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveal functional lncRNAs in oral cancer. PMID:32571304
Adaptation of the Marine Bacterium Shewanella baltica to Low Temperature Stress. PMID:32570789
Transcriptome analysis of a social caterpillar, Drepana arcuata: De novo assembly, functional annotation and developmental analysis. PMID:32569288
The acute effects of adjuvant radiation and chemotherapy on peripheral blood epigenetic age in early stage breast cancer patients. PMID:32566744
Downregulation of ST3GAL5 is associated with muscle invasion, high grade and a poor prognosis in patients with bladder cancer. PMID:32566010
Identification of key genes associated with the progression of intrahepatic cholangiocarcinoma using weighted gene co-expression network analysis. PMID:32565973
A novel prognostic signature of immune-related genes for patients with colorectal cancer. PMID:32564470
Prognostic characterization of OAS1/OAS2/OAS3/OASL in breast cancer. PMID:32560641
Engineered receptors for human cytomegalovirus that are orthogonal to normal human biology. PMID:32559251
Mitochondrial protein biogenesis in the synapse is supported by local translation. PMID:32558077
An analytical study of neocartilage from microtia and otoplasty surgical remnants: A possible application for BMP7 in microtia development and regeneration. PMID:32555733
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis. PMID:32555194
LC-FACSeq is a method for detecting rare clones in leukemia. PMID:32554930
COnTORT: COmprehensive Transcriptomic ORganizational Tool for Simultaneously Retrieving and Organizing Numerous Gene Expression Data Sets from the NCBI Gene Expression Omnibus Database. PMID:32554783
An age-independent gene signature for monitoring acute rejection in kidney transplantation. PMID:32550916
Upregulation of Piezo1 Is a Novel Prognostic Indicator in Glioma Patients. PMID:32547190
Identification of Hub Genes in Type 2 Diabetes Mellitus Using Bioinformatics Analysis. PMID:32547141
The Leader Peptide peTrpL Forms Antibiotic-Containing Ribonucleoprotein Complexes for Posttranscriptional Regulation of Multiresistance Genes. PMID:32546623
The novel lncRNA PTTG3P is downregulated and predicts poor prognosis in non-small cell lung cancer. PMID:32542097
TGF-β1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In Vivo. PMID:32531237
Bioinformatics analysis of the circRNA-miRNA-mRNA network for non-small cell lung cancer. PMID:32527185
metaRE R Package for Meta-Analysis of Transcriptome Data to Identify the cis-Regulatory Code behind the Transcriptional Reprogramming. PMID:32526881
CPPED1-targeting microRNA-371a-5p expression in human placenta associates with spontaneous delivery. PMID:32520951
KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis. PMID:32519739
Transcriptome-Based Analysis of Tomato Genotypes Resistant to Bacterial Spot (Xanthomonas perforans) Race T4. PMID:32517212
Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice. PMID:32510473
Comprehensive identification of a two-genesignature as a novel potential prognostic model for patients with medulloblastoma. PMID:32509164
How Do You Identify m6 A Methylation in Transcriptomes at High Resolution? A Comparison of Recent Datasets. PMID:32508872
Identification of immune-related biomarkers associated with tumorigenesis and prognosis in cutaneous melanoma patients. PMID:32508531
Can We Assume the Gene Expression Profile as a Proxy for Signaling Network Activity? PMID:32503292
Integrative analysis of key candidate genes and signaling pathways in autoimmune thyroid dysfunction related to anti-CTLA-4 therapy by bioinformatics. PMID:32500465
Circular RNA HIPK3: A Key Circular RNA in a Variety of Human Cancers. PMID:32500032
poly(UG)-tailed RNAs in genome protection and epigenetic inheritance. PMID:32499657
Expression profiling of small intestinal neuroendocrine tumors identified pathways and gene networks linked to tumorigenesis and metastasis. PMID:32496505
Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia. PMID:32493790
Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification. PMID:32492250
Leaf tissue specific transcriptome sequence and de novo assembly datasets of Asiatic mangrove Rhizophora mucronata Lam. PMID:32490096
Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation. PMID:32483278
Prognostic gene expression signature for high-grade serous ovarian cancer. PMID:32473302
Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression. PMID:32471474
Tissue-specific angiogenic and invasive properties of human neonatal thymus and bone MSCs: Role of SLIT3-ROBO1. PMID:32470195
Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PMID:32469866
Computational analysis and verification of molecular genetic targets for glioblastoma. PMID:32469390
Drug screening and identification of key candidate genes and pathways of rheumatoid arthritis. PMID:32468016
UBR5 regulates proliferation and radiosensitivity in human laryngeal carcinoma via the p38/MAPK signaling pathway. PMID:32468011
Novel Discoveries Targeting Pathogenic Gut Microbes and New Therapies in Pancreatic Cancer: Does Pathogenic E. coli Infection Cause Pancreatic Cancer Progression Modulated by TUBB/Rho/ROCK Signaling Pathway? A Bioinformatic Analysis. PMID:32461969
Genes Involved in Energy Metabolism Are Differentially Expressed During the Day-Night Cycle in Murine Retinal Pigment Epithelium. PMID:32460311
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway. PMID:32457332
Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. PMID:32453714
An up-to-date overview of computational polypharmacology in modern drug discovery. PMID:32452701
A novel risk score model based on eight genes and a nomogram for predicting overall survival of patients with osteosarcoma. PMID:32448271
Dyslexia Candidate Gene and Ciliary Gene Expression Dynamics During Human Neuronal Differentiation. PMID:32445086
Drought and plant litter chemistry alter microbial gene expression and metabolite production. PMID:32444813
Transcriptomic Evidence of Molecular Mechanisms Underlying the Response of Lactobacillus Plantarum WCFS1 to Hydroxytyrosol. PMID:32443873
Screening and identification of key biomarkers for retinoblastoma: Evidence from bioinformatics analysis. PMID:32443297
Elucidation of the RNA-granule inducing sodium azide stress response through transcriptome analysis. PMID:32437849
A meta-analysis of gene expression data highlights synaptic dysfunction in the hippocampus of brains with Alzheimer's disease. PMID:32433480
Functional Relevance of Citrulline in the Vegetative Tissues of Watermelon During Abiotic Stresses. PMID:32431723
The transition from acute to chronic pain: dynamic epigenetic reprogramming of the mouse prefrontal cortex up to 1 year after nerve injury. PMID:32427748
Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients - A Bioinformatics Approach. PMID:32426333
Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract. PMID:32425701
An NMF-Based Methodology for Selecting Biomarkers in the Landscape of Genes of Heterogeneous Cancer-Associated Fibroblast Populations. PMID:32425511
Comprehensive analysis reveals a six-gene signature and associated drugs in mimic inguinal hernia model. PMID:32424728
TFEB regulates murine liver cell fate during development and regeneration. PMID:32424153
Detecting qualitative changes in biological systems. PMID:32424123
Novel Non-integrating DNA Nano-S/MAR Vectors Restore Gene Function in Isogenic Patient-Derived Pancreatic Tumor Models. PMID:32420409
Screening and Identification of Differentially Expressed Genes Expressed among Left and Right Colon Adenocarcinoma. PMID:32420374
Key genes of renal tubular necrosis: a bioinformatics analysis. PMID:32420172
Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study. PMID:32419051
Myocardial micro-biopsy procedure for molecular characterization with increased precision and reduced trauma. PMID:32415191
CSN: unsupervised approach for inferring biological networks based on the genome alone. PMID:32414319
Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells. PMID:32410854
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver. PMID:32407006
An EGFR signature predicts cell line and patient sensitivity to multiple tyrosine kinase inhibitors. PMID:32406930
Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-Seq. PMID:32406872
Dietary lipids accumulate in macrophages and stromal cells and change the microarchitecture of mesenteric lymph nodes. PMID:32405435
Correlation-centred variable selection of a gene expression signature to predict breast cancer metastasis. PMID:32404965
MNase Profiling of Promoter Chromatin in Salmonella typhimurium-Stimulated GM12878 Cells Reveals Dynamic and Response-Specific Nucleosome Architecture. PMID:32404364
Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4. PMID:32403054
Neuronal activity increases translocator protein (TSPO) levels. PMID:32398717
Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data. PMID:32397130
PPARG Drives Molecular Networks as an Inhibitor for the Pathologic Development and Progression of Lung Adenocarcinoma. PMID:32395124
The Mnemiopsis Genome Project Portal: integrating new gene expression resources and improving data visualization. PMID:32386298
Bioinformatics Resources for Plant Abiotic Stress Responses: State of the Art and Opportunities in the Fast Evolving -Omics Era. PMID:32384671
A putative competing endogenous RNA network in cisplatin-resistant lung adenocarcinoma cells identifying potentially rewarding research targets. PMID:32382346
Aberrant expression of two miRNAs promotes proliferation, hepatitis B virus amplification, migration and invasion of hepatocellular carcinoma cells: evidence from bioinformatic analysis and experimental validation. PMID:32377460
Kaposi's Sarcoma-Associated Herpesvirus Fine-Tunes the Temporal Expression of Late Genes by Manipulating a Host RNA Quality Control Pathway. PMID:32376621
Construction of an integrated human osteosarcoma database, HOsDb, based on literature mining, microarray analysis, and database retrieval. PMID:32375685
Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells. PMID:32374402
Integrative Analysis for Elucidating Transcriptomics Landscapes of Glucocorticoid-Induced Osteoporosis. PMID:32373610
Mitral valve leaflet response to ischaemic mitral regurgitation: from gene expression to tissue remodelling. PMID:32370692
Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells. PMID:32370190
Multi-Gene Prognostic Signatures and Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy in ER-positive, HER2-negative Breast Cancer Patients. PMID:32369904
The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection. PMID:32369020
Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction. PMID:32366681
CPS1 expression and its prognostic significance in lung adenocarcinoma. PMID:32355785
Promising diagnostic and prognostic value of six genes in human hepatocellular carcinoma. PMID:32355538
The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice. PMID:32355198
JAK-STAT Activity in Peripheral Blood Cells and Kidney Tissue in IgA Nephropathy. PMID:32354727
Comparative proteogenomics profiling of non-small and small lung carcinoma cell lines using mass spectrometry. PMID:32351780
Polymorphisms in miRNA binding sites involved in metabolic diseases in mice and humans. PMID:32350386
Long-Term Aberrations To Cerebellar Endocannabinoids Induced By Early-Life Stress. PMID:32350298
EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress. PMID:32349972
Integrating SWATH-MS Proteomics and Transcriptome Analysis Identifies CHI3L1 as a Plasma Biomarker for Early Gastric Cancer. PMID:32346614
HMGA1-pseudogene7 transgenic mice develop B cell lymphomas. PMID:32341372
Interactions between DksA and Stress-Responsive Alternative Sigma Factors Control Inorganic Polyphosphate Accumulation in Escherichia coli. PMID:32341074
Identification of Key Genes Related to Lung Squamous Cell Carcinoma Using Bioinformatics Analysis. PMID:32340320
The Construction and Analysis of the Aberrant lncRNA-miRNA-mRNA Network in Adipose Tissue from Type 2 Diabetes Individuals with Obesity. PMID:32337289
GATA2 and Progesterone Receptor Interaction in Endometrial Stromal Cells Undergoing Decidualization. PMID:32335672
PHTF2 regulates lipids metabolism in gastric cancer. PMID:32335542
High dimensional model representation of log-likelihood ratio: binary classification with expression data. PMID:32334509
Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome. PMID:32327684
Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release. PMID:32327470
Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects. PMID:32326418
Comparative Transcriptomic Analysis of Subcutaneous Adipose Tissue from Local Pig Breeds. PMID:32326415
A Study of Gene Expression Changes in Human Spinal and Oculomotor Neurons; Identifying Potential Links to Sporadic ALS. PMID:32325953
Drought Stress Responses in Context-Specific Genome-Scale Metabolic Models of Arabidopsis thaliana. PMID:32325728
Computational Approach to Identifying Universal Macrophage Biomarkers. PMID:32322218
SPEED2: inferring upstream pathway activity from differential gene expression. PMID:32313938
Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis. PMID:32312741
Bioinformatics analysis and verification of gene targets for benign tracheal stenosis. PMID:32309912
Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder. PMID:32306996
The Molecular Processes in the Trabecular Meshwork After Exposure to Corticosteroids and in Corticosteroid-Induced Ocular Hypertension. PMID:32305042
Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity. PMID:32300166
Gene-Specific Control of tRNA Expression by RNA Polymerase II. PMID:32298650
Formation of colorectal liver metastases induces musculoskeletal and metabolic abnormalities consistent with exacerbated cachexia. PMID:32298240
20-Hydroxyecdysone Primes Innate Immune Responses That Limit Bacterial and Malarial Parasite Survival in Anopheles gambiae. PMID:32295874
Differences in the Transcriptomic Response of Campylobacter coli and Campylobacter lari to Heat Stress. PMID:32292399
An epigenetic map of malaria parasite development from host to vector. PMID:32286373
Altered Energy Metabolism During Early Optic Nerve Crush Injury: Implications of Warburg-Like Aerobic Glycolysis in Facilitating Retinal Ganglion Cell Survival. PMID:32277382
iMM1865: A New Reconstruction of Mouse Genome-Scale Metabolic Model. PMID:32277147
Whole-Genome DNA Methylation Profiling of CD14+ Monocytes Reveals Disease Status and Activity Differences in Crohn's Disease Patients. PMID:32276386
ngn-1/neurogenin Activates Transcription of Multiple Terminal Selector Transcription Factors in the Caenorhabditis elegans Nervous System. PMID:32273286
Molecular Fingerprints of Borderline Changes in Kidney Allografts Are Influenced by Donor Category. PMID:32269565
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation. PMID:32269263
A Targeted Multi-omic Analysis Approach Measures Protein Expression and Low-Abundance Transcripts on the Single-Cell Level. PMID:32268080
Identification of core genes associated with prostate cancer progression and outcome via bioinformatics analysis in multiple databases. PMID:32266115
Impact of ex vivo Sample Handling on DNA Methylation Profiles in Human Cord Blood and Neonatal Dried Blood Spots. PMID:32265984
Defining the Design Principles of Skin Epidermis Postnatal Growth. PMID:32259486
Landscape of copy number aberrations in esophageal squamous cell carcinoma from a high endemic region of South Africa. PMID:32252688
Role of uL3 in the Crosstalk between Nucleolar Stress and Autophagy in Colon Cancer Cells. PMID:32244996
Wnt signaling regulates neural plate patterning in distinct temporal phases with dynamic transcriptional outputs. PMID:32243887
Chemotherapy exacerbates ovarian cancer cell migration and cancer stem cell-like characteristics through GLI1. PMID:32242101
Geographic assessment of cancer genome profiling studies. PMID:32239182
Endothelialization of arterial vascular grafts by circulating monocytes. PMID:32238801
Epigenetic inhibitors eliminate senescent melanoma BRAFV600E cells that survive long‑term BRAF inhibition. PMID:32236593
LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma. PMID:32234847
The immune infiltration in clear cell Renal Cell Carcinoma and their clinical implications: A study based on TCGA and GEO databases. PMID:32231726
Egyptian Rousette IFN-ω Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells. PMID:32231668
A large-scale comparative study of isoform expressions measured on four platforms. PMID:32228441
Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells. PMID:32227433
Decreased Expression of NUSAP1 Predicts Poor Overall Survival in Cervical Cancer. PMID:32226503
The CEDAR Workbench: An Ontology-Assisted Environment for Authoring Metadata that Describe Scientific Experiments. PMID:32219223
Valine-Induced Isoleucine Starvation in Escherichia coli K-12 Studied by Spike-In Normalized RNA Sequencing. PMID:32211022
Evidence of defined temporal expression patterns that lead a gram-negative cell out of dormancy. PMID:32203501
A novel stratification framework for predicting outcome in patients with prostate cancer. PMID:32203215
Fast tree aggregation for consensus hierarchical clustering. PMID:32197576
Tip of the iceberg: roles of circRNAs in hematological malignancies. PMID:32195014
Integrated bioinformatics analysis of the association between apolipoprotein E expression and patient prognosis in papillary thyroid carcinoma. PMID:32194729
IRF1 association with tumor immune microenvironment and use as a diagnostic biomarker for colorectal cancer recurrence. PMID:32194669
Arabidopsis Flippases Cooperate with ARF GTPase Exchange Factors to Regulate the Trafficking and Polarity of PIN Auxin Transporters. PMID:32193204
Neutrophil extracellular traps promote macrophage inflammation and impair atherosclerosis resolution in diabetic mice. PMID:32191637
Deletion of fatty acid transport protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes. PMID:32188695
Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer. PMID:32188493
Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia. PMID:32186681
Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach. PMID:32183784
Identification of key genes and pathways of diagnosis and prognosis in cervical cancer by bioinformatics analysis. PMID:32181600
Dataset of Cavendish banana transcriptome in response to chitosan coating application. PMID:32181300
Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart. PMID:32179820
Enabling population assignment from cancer genomes with SNP2pop. PMID:32179800
Epigenetic Regulation of ABA-Induced Transcriptional Responses in Maize. PMID:32179621
The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis. PMID:32176689
RNA-seq Analysis of Wild-Type vs. FOXC2-Deficient Melanoma Cells Reveals a Role for the FOXC2 Transcription Factor in the Regulation of Multiple Oncogenic Pathways. PMID:32175283
A transcriptional landscape of 28 porcine tissues obtained by super deepSAGE sequencing. PMID:32171242
Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice. PMID:32170957
*-DCC: A platform to collect, annotate, and explore a large variety of sequencing experiments. PMID:32170312
Single-cell RNA sequencing reveals a heterogeneous response to Glucocorticoids in breast cancer cells. PMID:32170217
Cystic renal-epithelial derived induced pluripotent stem cells from polycystic kidney disease patients. PMID:32163234
Screening and identification of critical biomarkers in erectile dysfunction: evidence from bioinformatic analysis. PMID:32161689
The Arabidopsis SAFEGUARD1 suppresses singlet oxygen-induced stress responses by protecting grana margins. PMID:32161131
Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics. PMID:32158542
Evaluation of pre-processing on the meta-analysis of DNA methylation data from the Illumina HumanMethylation450 BeadChip platform. PMID:32155174
Whole-Transcriptome Analysis Unveils the Synchronized Activities of Genes for Fructans in Developing Tubers of the Jerusalem Artichoke. PMID:32153609
Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development. PMID:32152089
The Application of Deep Learning in Cancer Prognosis Prediction. PMID:32150991
Biocomplexity and Fractality in the Search of Biomarkers of Aging and Pathology: Mitochondrial DNA Profiling of Parkinson's Disease. PMID:32143500
Understanding the Molecular Mechanisms of Asthma through Transcriptomics. PMID:32141255
Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks. PMID:32138627
Evaluation of Seven Different RNA-Seq Alignment Tools Based on Experimental Data from the Model Plant Arabidopsis thaliana. PMID:32138290
Histone H4 dosage modulates DNA damage response in the pathogenic yeast Candida glabrata via homologous recombination pathway. PMID:32134928
Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development. PMID:32130894
Supervised learning is an accurate method for network-based gene classification. PMID:32129827
Leptin and fractalkine: novel subcutaneous cytokines in burn injury. PMID:32127397
Hypoxia is regulating enzymatic wood decomposition and intracellular carbohydrate metabolism in filamentous white rot fungus. PMID:32123543
Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression. PMID:32117864
Erratum: Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells. PMID:32117464
Evaluation of Pathway Activation for a Single Sample Toward Inflammatory Bowel Disease Classification. PMID:32117426
A TRANSPARENT TESTA Transcriptional Module Regulates Endothelium Polarity. PMID:32117351
The Epipeptide YydF Intrinsically Triggers the Cell Envelope Stress Response of Bacillus subtilis and Causes Severe Membrane Perturbations. PMID:32117169
Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer. PMID:32115889
A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles. PMID:32111252
Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions. PMID:32110278
Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency. PMID:32109377
Investigation of the quorum-sensing regulon of the biocontrol bacterium Pseudomonas chlororaphis strain PA23. PMID:32109244
Molecular and genetic regulation of pig pancreatic islet cell development. PMID:32108026
Role of miRNA-542-5p in the tumorigenesis of osteosarcoma. PMID:32105410
Integrative module analysis of HCC gene expression landscapes. PMID:32104233
High-Throughput Fluorescence-Based Screen Identifies the Neuronal MicroRNA miR-124 as a Positive Regulator of Alphavirus Infection. PMID:32102877
Functional omics analyses reveal only minor effects of microRNAs on human somatic stem cell differentiation. PMID:32094412
Equivalent change enrichment analysis: assessing equivalent and inverse change in biological pathways between diverse experiments. PMID:32093613
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity. PMID:32091410
Transcriptional analysis of arogenate dehydratase genes identifies a link between phenylalanine biosynthesis and lignin biosynthesis. PMID:32090267
Circulating and tissue matricellular RNA and protein expression in calcific aortic valve disease. PMID:32089075
Transcriptomics at Maize Embryo/Endosperm Interfaces Identifies a Transcriptionally Distinct Endosperm Subdomain Adjacent to the Embryo Scutellum. PMID:32086366
RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors. PMID:32086342
Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology. PMID:32085461
Development of a four-gene prognostic model for pancreatic cancer based on transcriptome dysregulation. PMID:32081836
Disrupted Gene Networks in Subfertile Hybrid House Mice. PMID:32076722
Data on banana transcriptome in response to blood disease infection. PMID:32071957
Prognostic values of a novel multi-mRNA signature for predicting relapse of cholangiocarcinoma. PMID:32071556
Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. PMID:32071286
Genome-Wide Analysis of Gene Expression Provides New Insights into Waterlogging Responses in Barley (Hordeum vulgare L.). PMID:32069892
Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes. PMID:32068945
IPF pathogenesis is dependent upon TGFβ induction of IGF-1. PMID:32067272
Identification of core biomarkers associated with pathogenesis and prognostic outcomes of laryngeal squamous-cell cancer using bioinformatics analysis. PMID:32067095
A Post-Processing Algorithm for miRNA Microarray Data. PMID:32059403
Computational discovery of therapeutic candidates for preventing preterm birth. PMID:32051340
Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish. PMID:32051014
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data. PMID:32051003
Differential Regulation of circRNA, miRNA, and piRNA during Early Osteogenic and Chondrogenic Differentiation of Human Mesenchymal Stromal Cells. PMID:32050423
Transcriptional Signatures of Tau and Amyloid Neuropathology. PMID:32049030
Using the Gibbs Function as a Measure of Human Brain Development Trends from Fetal Stage to Advanced Age. PMID:32046179
A Functional Landscape of CKD Entities From Public Transcriptomic Data. PMID:32043035
The health status alters the pituitary function and reproduction of mice in a Cxcr2-dependent manner. PMID:32041848
Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate Adenocarcinoma. PMID:32041153
Distinct cachexia profiles in response to human pancreatic tumours in mouse limb and respiratory muscle. PMID:32039571
Using SNP Weights Derived From Gene Expression Modules to Improve GWAS Power for Feed Efficiency in Pigs. PMID:32038708
APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis. PMID:32037952
Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. PMID:32034172
Determining sequencing depth in a single-cell RNA-seq experiment. PMID:32034137
Combined Use of Three Machine Learning Modeling Methods to Develop a Ten-Gene Signature for the Diagnosis of Ventilator-Associated Pneumonia. PMID:32031163
Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma. PMID:32028068
Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues. PMID:32024885
PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis. PMID:32023084
Construction of a prognosis‑associated long noncoding RNA‑mRNA network for multiple myeloma based on microarray and bioinformatics analysis. PMID:32016443
The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels. PMID:32016368
Exploring the Key Genes and Pathways in the Formation of Corneal Scar Using Bioinformatics Analysis. PMID:32016117
Comparison of DNA methylation profiles from saliva in Coeliac disease and non-coeliac disease individuals. PMID:32014011
Limited utility of qPCR-based detection of tumor-specific circulating mRNAs in whole blood from clear cell renal cell carcinoma patients. PMID:32013938
Identification of differentially expressed protein-coding genes in lung adenocarcinomas. PMID:32010276
RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs for discerning baseline expression exclusivity of candidate biomarkers. PMID:32009518
Unveiling ncRNA regulatory axes in atherosclerosis progression. PMID:32009226
Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors. PMID:32004478
Knowledge-enhanced biomedical named entity recognition and normalization: application to proteins and genes. PMID:32000677
Changes in gene expression in human skeletal stem cells transduced with constitutively active Gsα correlates with hallmark histopathological changes seen in fibrous dysplastic bone. PMID:31999703
Triangular correlation (TrC) between cancer aggressiveness, cell uptake capability, and cell deformability. PMID:31998832
Identification of Key Genes and Prognostic Analysis between Chromophobe Renal Cell Carcinoma and Renal Oncocytoma by Bioinformatic Analysis. PMID:31998788
Interleukin-1 Beta-Mediated Sex Differences in Kawasaki Disease Vasculitis Development and Response to Treatment. PMID:31996019
Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source. PMID:31993211
Identification of Key Biomarkers in Bladder Cancer: Evidence from a Bioinformatics Analysis. PMID:31991631
Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms. PMID:31988098
Upregulation of Hallmark Muscle Genes Protects GneM743T/M743T Mutated Knock-In Mice From Kidney and Muscle Phenotype. PMID:31985472
Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation. PMID:31978041
MicroRNA Biomarker hsa-miR-195-5p for Detecting the Risk of Lung Cancer. PMID:31976313
Integrated, multicohort analysis reveals unified signature of systemic lupus erythematosus. PMID:31971918
MicroRNAs and regulated interaction networks reveal differences between adult and pediatric acute myeloid leukemia. PMID:31966399
CRL4-Cereblon complex in Thalidomide Embryopathy: a translational investigation. PMID:31964914
A qualitative transcriptional signature for predicting the biochemical recurrence risk of prostate cancer patients after radical prostatectomy. PMID:31961962
Ontology-driven integrative analysis of omics data through Onassis. PMID:31959844
Manatee: detection and quantification of small non-coding RNAs from next-generation sequencing data. PMID:31959833
CeRNA regulatory network-based analysis to study the roles of noncoding RNAs in the pathogenesis of intrahepatic cholangiocellular carcinoma. PMID:31956102
Mining the proliferative diabetic retinopathy-associated genes and pathways by integrated bioinformatic analysis. PMID:31953631
Large-scale Analyses of Disease Biomarkers and Apremilast Pharmacodynamic Effects. PMID:31953524
Identification of biomarkers in common chronic lung diseases by co-expression networks and drug-target interactions analysis. PMID:31952466
Antiviral activity of interferon-stimulated gene 20, as a putative repressor binding to hepatitis B virus enhancer II and core promoter. PMID:31951295
tRNA 2'-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila. PMID:31943105
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. PMID:31942009
Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor. PMID:31940495
The Arabidopsis Protein CGL20 Is Required for Plastid 50S Ribosome Biogenesis. PMID:31937683
Changes in the expression of genes encoding type IV pili-associated proteins are seen when Clostridium perfringens is grown in liquid or on surfaces. PMID:31937237
Comparing DNA methylation profiles across different tissues associated with the diagnosis of pediatric asthma. PMID:31932625
Future of Evidence Synthesis in Precision Oncology: Between Systematic Reviews and Biocuration. PMID:31930186
SCDC: bulk gene expression deconvolution by multiple single-cell RNA sequencing references. PMID:31925417
Array Comparative Genomic Hybridization Analysis Reveals Significantly Enriched Pathways in Canine Oral Melanoma. PMID:31921654
Rainbow Trout IgM+ B Cells Preferentially Respond to Thymus-Independent Antigens but Are Activated by CD40L. PMID:31921163
Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics. PMID:31918046
A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction. PMID:31918006
DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation. PMID:31914996
Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration. PMID:31914683
PROP1-Dependent Retinoic Acid Signaling Regulates Developmental Pituitary Morphogenesis and Hormone Expression. PMID:31913463
Evaluation of the 12-Gene Molecular Score and the 21-Gene Recurrence Score as Predictors of Response to Neo-adjuvant Chemotherapy in Estrogen Receptor-Positive, HER2-Negative Breast Cancer. PMID:31907749
Identification and characterization of genes frequently responsive to Xanthomonas oryzae pv. oryzae and Magnaporthe oryzae infections in rice. PMID:31906847
MatchMixeR: a cross-platform normalization method for gene expression data integration. PMID:31904810
Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma. PMID:31900160
Differential Expression Gene Explorer (DrEdGE): a tool for generating interactive online visualizations of gene expression datasets. PMID:31899488
Insights into the Gene Expression Profiles of Active and Restricted Red/Green-HIV+ Human Astrocytes: Implications for Shock or Lock Therapies in the Brain. PMID:31896591
Robust hepatitis E virus infection and transcriptional response in human hepatocytes. PMID:31896581
Integrative Gene Expression Profiling Analysis to Investigate Potential Prognostic Biomarkers for Colorectal Cancer. PMID:31893510
A 6-Membrane Protein Gene score for prognostic prediction of cytogenetically normal acute myeloid leukemia in multiple cohorts. PMID:31892991
A systems biology approach uncovers a gene co-expression network associated with cell wall degradability in maize. PMID:31891625
Estrogen activates Alzheimer's disease genes. PMID:31890855
Integrative Analysis of Axolotl Gene Expression Data from Regenerative and Wound Healing Limb Tissues. PMID:31889169
CD4+ T Cell-Derived NGAL Modifies the Outcome of Ischemic Acute Kidney Injury. PMID:31889023
High-level integration of murine intestinal transcriptomics data highlights the importance of the complement system in mucosal homeostasis. PMID:31888466
Unique molecular signature in mucolipidosis type IV microglia. PMID:31883529
Increased HLA-DR expression and cortical demyelination in MS links with HLA-DR15. PMID:31882398
Venn-diaNet : venn diagram based network propagation analysis framework for comparing multiple biological experiments. PMID:31881980
PROMO: an interactive tool for analyzing clinically-labeled multi-omic cancer datasets. PMID:31878868
Habitat-Specific Clock Variation and Its Consequence on Reproductive Fitness. PMID:31878828
Arabidopsis EDR1 Protein Kinase Regulates the Association of EDS1 and PAD4 to Inhibit Cell Death. PMID:31876224
A robustness metric for biological data clustering algorithms. PMID:31874625
Syk degradation restrains plasma cell formation and promotes zonal transitions in germinal centers. PMID:31873727
Expression of Alpha-type Platelet-derived Growth Factor Receptor-influenced Genes Predicts Clinical Outcome in Glioma. PMID:31869747
Transcriptional regulation of a gonococcal gene encoding a virulence factor (L-lactate permease). PMID:31860664
StressGenePred: a twin prediction model architecture for classifying the stress types of samples and discovering stress-related genes in arabidopsis. PMID:31856731
Knowledge Base Commons (KBCommons) v1.1: a universal framework for multi-omics data integration and biological discoveries. PMID:31856718
Bioinformatic profiling identifies a platinum-resistant-related risk signature for ovarian cancer. PMID:31856408
Early cold stress responses in post-meiotic anthers from tolerant and sensitive rice cultivars. PMID:31853825
The InsP7 phosphatase Siw14 regulates inositol pyrophosphate levels to control localization of the general stress response transcription factor Msn2. PMID:31848224
Loss of ADAMTS19 causes progressive non-syndromic heart valve disease. PMID:31844321
Supplementation of live yeast based feed additive in early life promotes rumen microbial colonization and fibrolytic potential in lambs. PMID:31844130
Vascular PPARβ/δ Promotes Tumor Angiogenesis and Progression. PMID:31842402
Epigenetic Modifications in T Cells: The Role of DNA Methylation in Salt-Sensitive Hypertension. PMID:31838911
High-resolution chromosomal microarray analysis for copy-number variations in high-functioning autism reveals large aberration typical for intellectual disability. PMID:31838600
Transcriptomic and Proteomic Responses of the Organohalide-Respiring Bacterium Desulfoluna spongiiphila to Growth with 2,6-Dibromophenol as the Electron Acceptor. PMID:31836581
An Integrated Pan-Cancer Analysis and Structure-Based Virtual Screening of GPR15. PMID:31835584
Differences in the intrinsic spatial dynamics of the chromatin contribute to cell differentiation. PMID:31828312
Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans. PMID:31827597
PPP2R2A prostate cancer haploinsufficiency is associated with worse prognosis and a high vulnerability to B55α/PP2A reconstitution that triggers centrosome destabilization. PMID:31822657
Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. PMID:31822609
Longitudinal linear combination test for gene set analysis. PMID:31822265
The functional landscape of the human phosphoproteome. PMID:31819260
Distinct patterns of complex rearrangements and a mutational signature of microhomeology are frequently observed in PLP1 copy number gain structural variants. PMID:31818324
Identification of potential core genes in metastatic renal cell carcinoma using bioinformatics analysis. PMID:31814889
GliomaDB: A Web Server for Integrating Glioma Omics Data and Interactive Analysis. PMID:31811943
Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies. PMID:31811247
Modelling the gene expression and the DNA-binding in the 3T3-L1 differentiating adipocytes. PMID:31809632
Clinical significance of the immune cell landscape in hepatocellular carcinoma patients with different degrees of fibrosis. PMID:31807510
Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID. PMID:31804490
Stress-induced changes in the expression of antioxidant system genes for rice (Oryza sativa L.) and bread wheat (Triticum aestivum L.). PMID:31803533
c-Jun overexpression in CAR T cells induces exhaustion resistance. PMID:31802004
mitoXplorer, a visual data mining platform to systematically analyze and visualize mitochondrial expression dynamics and mutations. PMID:31799603
Macrophage Coordination of the Interferon Lambda Immune Response. PMID:31798594
aTEMPO: Pathway-Specific Temporal Anomalies for Precision Therapeutics. PMID:31797638
The Transcriptional Profile of Trichophyton rubrum Co-Cultured with Human Keratinocytes Shows New Insights about Gene Modulation by Terbinafine. PMID:31795354
Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle. PMID:31794382
Identification of Susceptibility Genes to Allergic Rhinitis by Gene Expression Data Sets. PMID:31794148
Bioinformatics analysis of Ewing's sarcoma: Seeking key candidate genes and pathways. PMID:31788075
Identification of the lncRNA-miRNA-mRNA network associated with gastric cancer via integrated bioinformatics analysis. PMID:31788050
Microarray Gene Expression Dataset Re-analysis Reveals Variability in Influenza Infection and Vaccination. PMID:31787983
Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation. PMID:31786364
Gene Expression Value Prediction Based on XGBoost Algorithm. PMID:31781160
Dissection of gene expression datasets into clinically relevant interaction signatures via high-dimensional correlation maximization. PMID:31780653
Histone Lysine Methylation Dynamics Control EGFR DNA Copy-Number Amplification. PMID:31776131
IL-1β Induces SOCS2 Expression in Human Dendritic Cells. PMID:31775389
A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subtyping. PMID:31774481
Commensal microbiota drive the functional diversification of colon macrophages. PMID:31772323
Network Modeling Approaches and Applications to Unravelling Non-Alcoholic Fatty Liver Disease. PMID:31771247
Screening and identification of key biomarkers in nasopharyngeal carcinoma: Evidence from bioinformatic analysis. PMID:31770211
Expression of the BAD pathway is a marker of triple-negative status and poor outcome. PMID:31767884
JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. PMID:31767855
Deep Characterization of the Human Antibody Response to Natural Infection Using Longitudinal Immune Repertoire Sequencing. PMID:31767621
BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium. PMID:31767620
Computational Inference of Gene Co-Expression Networks for the identification of Lung Carcinoma Biomarkers: An Ensemble Approach. PMID:31766738
Bioinformatics analyses of publicly available NEPCa datasets. PMID:31763364
Repurposing Drugs by In Silico Methods to Target BCR Kinase Domain in Chronic Myeloid Leukemia. PMID:31759365
Endothelial Cell-Specific Transcriptome Reveals Signature of Chronic Stress Related to Worse Outcome After Mild Transient Brain Ischemia in Mice. PMID:31758402
Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling. PMID:31758074
TACITuS: transcriptomic data collector, integrator, and selector on big data platform. PMID:31757212
The influence of PFK-II overexpression on neuroblastoma patients' survival may be dependent on the particular isoenzyme expressed, PFKFB3 or PFKFB4. PMID:31754349
Monocytes affect bone mineral density in pre- and postmenopausal women through ribonucleoprotein complex biogenesis by integrative bioinformatics analysis. PMID:31754224
iCrotoK-PseAAC: Identify lysine crotonylation sites by blending position relative statistical features according to the Chou's 5-step rule. PMID:31751380
Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast. PMID:31748520
Screening and identification of key biomarkers in prostate cancer using bioinformatics. PMID:31746380
A-Lister: a tool for analysis of differentially expressed omics entities across multiple pairwise comparisons. PMID:31744472
Identification of a 6-lncRNA prognostic signature based on microarray re-annotation in gastric cancer. PMID:31743579
Elevating acetyl-CoA levels reduces aspects of brain aging. PMID:31742554
Differences in the importance of microcephaly, dysmorphism, and epilepsy in the detection of pathogenic CNVs in ID and ASD patients. PMID:31741789
The Microalga Nannochloropsis during Transition from Quiescence to Autotrophy in Response to Nitrogen Availability. PMID:31740503
Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer. PMID:31736281
The Gα-interacting vesicle-associated protein interacts with and promotes cell surface localization of GRP78 during endoplasmic reticulum stress. PMID:31736058
Gene expression microarray public dataset reanalysis in chronic obstructive pulmonary disease. PMID:31730674
Identification of key biomarkers associated with development and prognosis in patients with ovarian carcinoma: evidence from bioinformatic analysis. PMID:31729978
Transcriptome analysis of Aspergillus niger xlnR and xkiA mutants grown on corn Stover and soybean hulls reveals a highly complex regulatory network. PMID:31726994
Proteomic and transcriptomic analyses of early and late-chronic Toxoplasma gondii infection shows novel and stage specific transcripts. PMID:31726967
Correlative evidence for co-regulation of phosphorus and carbon exchanges with symbiotic fungus in the arbuscular mycorrhizal Medicago truncatula. PMID:31710651
Assessing the Impact of Sample Heterogeneity on Transcriptome Analysis of Human Diseases Using MDP Webtool. PMID:31708960
Two Loci, RiAF3 and RiAF4, Contribute to the Annual-Fruiting Trait in Rubus. PMID:31708950
Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission. PMID:31708905
Mutation of the PTCH1 gene predicts recurrence of breast cancer. PMID:31704974
Defining the impact of exoribonucleases in the shift between exponential and stationary phases. PMID:31700028
Identification of Hub Genes and Pathways in a Rat Model of Renal Ischemia-Reperfusion Injury Using Bioinformatics Analysis of the Gene Expression Omnibus (GEO) Dataset and Integration of Gene Expression Profiles. PMID:31699960
DNA methylation profiles capturing breast cancer heterogeneity. PMID:31699026
Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing ORAI1. PMID:31698854
Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo. PMID:31697837
Genetic Interactions Affect Lung Function in Patients with Systemic Sclerosis. PMID:31694854
The role of nitric oxide during embryonic wound healing. PMID:31694542
Rapid Discovery of Potential Drugs for Osteonecrosis of Femoral Head Based on Gene Expression Omnibus Database and Connectivity Map. PMID:31692295
Development of Tissue-Specific Age Predictors Using DNA Methylation Data. PMID:31690030
NK cell defects in X-linked pigmentary reticulate disorder. PMID:31672938
Non-Invasive Approach for Evaluation of Pulmonary Hypertension Using Extracellular Vesicle-Associated Small Non-Coding RNA. PMID:31671920
Complex Interactions between Cohesin and CTCF in Regulation of Kaposi's Sarcoma-Associated Herpesvirus Lytic Transcription. PMID:31666380
Synchronized replication of genes encoding the same protein complex in fast-proliferating cells. PMID:31662304
Proteasome inhibition preserves longitudinal growth of denervated muscle and prevents neonatal neuromuscular contractures. PMID:31661460
miR‑760 regulates skeletal muscle proliferation in rheumatoid arthritis by targeting Myo18b. PMID:31661144
The FOXC2 Transcription Factor Promotes Melanoma Outgrowth and Regulates Expression of Genes Associated With Drug Resistance and Interferon Responsiveness. PMID:31659103
High Expression of TTYH3 is Related to Poor Clinical Outcomes in Human Gastric Cancer. PMID:31652813
Identification of 15 T Cell Restricted Genes Evaluates T Cell Infiltration of Human Healthy Tissues and Cancers and Shows Prognostic and Predictive Potential. PMID:31652661
Generation and function of progenitor T cells from StemRegenin-1-expanded CD34+ human hematopoietic progenitor cells. PMID:31648315
Acute sprint exercise transcriptome in human skeletal muscle. PMID:31647849
Multi-tissue network analysis for drug prioritization in knee osteoarthritis. PMID:31645614
Network-Based Functional Prediction Augments Genetic Association To Predict Candidate Genes for Histamine Hypersensitivity in Mice. PMID:31645420
Integrated bioinformatics analysis reveals role of the LINC01093/miR-96-5p/ZFAND5/NF-κB signaling axis in hepatocellular carcinoma. PMID:31641376
Size matters: how sample size affects the reproducibility and specificity of gene set analysis. PMID:31639047
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control. PMID:31636652
Luteal Lipids Regulate Progesterone Production and May Modulate Immune Cell Function During the Estrous Cycle and Pregnancy. PMID:31636603
TFAP2C regulates carbonic anhydrase XII in human breast cancer. PMID:31636386
Different Pathways Mediate Amphotericin-Lactoferrin Drug Synergy in Cryptococcus and Saccharomyces. PMID:31632362
Global Transcriptional Response of Three Highly Acid-Tolerant Field Strains of Listeria monocytogenes to HCl Stress. PMID:31623206
Identification of prognostic biomarkers for malignant melanoma using microarray datasets. PMID:31620197
Oleuropein Transcriptionally Primes Lactobacillus plantarum to Interact With Plant Hosts. PMID:31620115
Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells. PMID:31620083
Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3. PMID:31619268
Variance-Preserving Estimation of Intensity Values Obtained From Omics Experiments. PMID:31616468
Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota. PMID:31616404
D-GPM: A Deep Learning Method for Gene Promoter Methylation Inference. PMID:31615113
Electron transport chain biogenesis activated by a JNK-insulin-Myc relay primes mitochondrial inheritance in Drosophila. PMID:31612862
POPDC3 is a potential biomarker for prognosis and radioresistance in patients with head and neck squamous cell carcinoma. PMID:31612055
Screening and authentication of molecular markers in malignant glioblastoma based on gene expression profiles. PMID:31611967
Identification of key biomarkers and potential molecular mechanisms in lung cancer by bioinformatics analysis. PMID:31611952
Myo-REG: A Portal for Signaling Interactions in Muscle Regeneration. PMID:31611808
The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells. PMID:31611402
Transcriptional activation of CBFβ by CDK11p110 is necessary to promote osteosarcoma cell proliferation. PMID:31610798
pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks. PMID:31608109
Gene expression profiling of whole blood: A comparative assessment of RNA-stabilizing collection methods. PMID:31600258
β-Catenin mutations as determinants of hepatoblastoma phenotypes in mice. PMID:31597698
Enhanced Ex Vivo Generation of Erythroid Cells from Human Induced Pluripotent Stem Cells in a Simplified Cell Culture System with Low Cytokine Support. PMID:31595840
Global gene expression analysis of Escherichia coli K-12 DH5α after exposure to 2.4 GHz wireless fidelity radiation. PMID:31595026
Functional Genomics of the Retina to Elucidate its Construction and Deconstruction. PMID:31590277
Identification of PIKfyve kinase as a target in multiple myeloma. PMID:31582538
Screening and Identification of Potential Prognostic Biomarkers in Adrenocortical Carcinoma. PMID:31572440
Maternal Obesity Alters Neurotrophin-Associated MAPK Signaling in the Hypothalamus of Male Mouse Offspring. PMID:31572115
Degradation of the transcription factors PIF4 and PIF5 under UV-B promotes UVR8-mediated inhibition of hypocotyl growth in Arabidopsis. PMID:31571300
Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells. PMID:31569627
Delineating the role of MITF isoforms in pigmentation and tissue homeostasis. PMID:31562697
Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway. PMID:31558096
A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. PMID:31557719
ELTD1 facilitates glioma proliferation, migration and invasion by activating JAK/STAT3/HIF-1α signaling axis. PMID:31554859
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells. PMID:31548729
Screening and identification of biomarkers for systemic sclerosis via microarray technology. PMID:31545397
Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies. PMID:31543463
Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs. PMID:31542693
miR-511-3p protects against cockroach allergen-induced lung inflammation by antagonizing CCL2. PMID:31536479
Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3. PMID:31534498
Myceliophthora thermophila Xyr1 is predominantly involved in xylan degradation and xylose catabolism. PMID:31534479
FPR1 is the plague receptor on host immune cells. PMID:31534221
Comparative transcriptome analysis of the human endocervix and ectocervix during the proliferative and secretory phases of the menstrual cycle. PMID:31530865
Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells. PMID:31523390
Rectal cancer sub-clones respond differentially to neoadjuvant therapy. PMID:31521947
Identification of differentially expressed genes between primary lung cancer and lymph node metastasis via bioinformatic analysis. PMID:31516588
Cross-disease analysis identified novel common genes for both lung adenocarcinoma and lung squamous cell carcinoma. PMID:31516564
Construction of gene causal regulatory networks using microarray data with the coefficient of intrinsic dependence. PMID:31512008
Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials. PMID:31511426
Weighted elastic net for unsupervised domain adaptation with application to age prediction from DNA methylation data. PMID:31510704
A statistical simulator scDesign for rational scRNA-seq experimental design. PMID:31510652
Model-based optimization of subgroup weights for survival analysis. PMID:31510644
Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution. PMID:31504820
SNV identification from single-cell RNA sequencing data. PMID:31504520
Genome-Scale Characterization of Toxicity-Induced Metabolic Alterations in Primary Hepatocytes. PMID:31501904
Seminal fluid compromises visual perception in honeybee queens reducing their survival during additional mating flights. PMID:31500699
Combination of Cannabinoids, Δ9- Tetrahydrocannabinol and Cannabidiol, Ameliorates Experimental Multiple Sclerosis by Suppressing Neuroinflammation Through Regulation of miRNA-Mediated Signaling Pathways. PMID:31497013
p13CMFA: Parsimonious 13C metabolic flux analysis. PMID:31490922
Bioinformatic evidences and analysis of putative biomarkers in pancreatic ductal adenocarcinoma. PMID:31489384
Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy. PMID:31484655
Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection. PMID:31482013
Complex Responses to Hydrogen Peroxide and Hypochlorous Acid by the Probiotic Bacterium Lactobacillus reuteri. PMID:31481604
Modulating Pathogenesis with Mobile-CRISPRi. PMID:31481541
Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease. PMID:31477183
Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome. PMID:31476910
Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo. PMID:31475747
Prospects of genomic resources available at the global databases for the flora of United Arab Emirates. PMID:31475085
A Tridimensional Model for NK Cell-Mediated ADCC of Follicular Lymphoma. PMID:31475004
Screening and identification of potential target genes in head and neck cancer using bioinformatics analysis. PMID:31452775
Identification of aberrantly methylated differentially expressed genes in glioblastoma multiforme and their association with patient survival. PMID:31452706
Calvarial osteoblast gene expression in patients with craniosynostosis leads to novel polygenic mouse model. PMID:31442251
The Inducible Response of the Nematode Caenorhabditis elegans to Members of Its Natural Microbiota Across Development and Adult Life. PMID:31440221
miR-30 Family miRNAs Mediate the Effect of Chronic Social Defeat Stress on Hippocampal Neurogenesis in Mouse Depression Model. PMID:31440139
An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets. PMID:31438843
Statistical genomics in rare cancer. PMID:31437624
Identification of miRNAs involved in fruit ripening by deep sequencing of Olea europaea L. transcriptome. PMID:31437230
Gene networks underlying the early regulation of Paraburkholderia phytofirmans PsJN induced systemic resistance in Arabidopsis. PMID:31437216
FXYD5 (Dysadherin) upregulation predicts shorter survival and reveals platinum resistance in high-grade serous ovarian cancer patients. PMID:31434988
Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells. PMID:31434974
Regulation of Macrophage Foam Cell Formation During Nitrogen Mustard (NM)-Induced Pulmonary Fibrosis by Lung Lipids. PMID:31428777
Dysregulation of DNA methylation patterns may identify patients with breast cancer resistant to endocrine therapy: A predictive classifier based on differentially methylated regions. PMID:31423189
Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson's disease. PMID:31419995
Moving from Empirical to Rational Vaccine Design in the 'Omics' Era. PMID:31416125
Assessing phenotype order in molecular data. PMID:31409831
Progress in data interoperability to support computational toxicology and chemical safety evaluation. PMID:31404555
Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model. PMID:31404112
Nascent Polypeptide Domain Topology and Elongation Rate Direct the Cotranslational Hierarchy of Hsp70 and TRiC/CCT. PMID:31400849
Physiological and Transcriptional Responses of Candida parapsilosis to Exogenous Tyrosol. PMID:31399405
Accurate ethnicity prediction from placental DNA methylation data. PMID:31399127
Can Biofilm Be Reversed Through Quorum Sensing in Pseudomonas aeruginosa? PMID:31396166
Folate can promote the methionine-dependent reprogramming of glioblastoma cells towards pluripotency. PMID:31395852
Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis. PMID:31391082
Long Non-Coding RNA Expression Levels Modulate Cell-Type-Specific Splicing Patterns by Altering Their Interaction Landscape with RNA-Binding Proteins. PMID:31390792
Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage. PMID:31388185
Interaction Among Sex, Aging, and Epigenetic Processes Concerning Visceral Fat, Insulin Resistance, and Dyslipidaemia. PMID:31379754
Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration. PMID:31375810
Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patients. PMID:31375728
Gene Expression Profiling Reveals that PXR Activation Inhibits Hepatic PPARα Activity and Decreases FGF21 Secretion in Male C57Bl6/J Mice. PMID:31374856
Exploring induced pluripotency in human fibroblasts via construction, validation, and application of a gene regulatory network. PMID:31374103
Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways. PMID:31373129
RNA sequencing data of cultured primary rat Müller cells, the spontaneously immortalized rat Müller cell line, SIRMu-1, and the SV40-transformed rat Müller cell line, rMC-1. PMID:31372389
Disparity in Tumor Immune Microenvironment of Breast Cancer and Prognostic Impact: Asian Versus Western Populations. PMID:31371522
The prognostic value of JUNB-positive CTCs in metastatic breast cancer: from bioinformatics to phenotypic characterization. PMID:31370904
Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology. PMID:31366909
Daphnia stressor database: Taking advantage of a decade of Daphnia '-omics' data for gene annotation. PMID:31366898
Evaluation of the Common Molecular Basis in Alzheimer's and Parkinson's Diseases. PMID:31366155
Mining of Self-Organizing Map Gene-Expression Portraits Reveals Prognostic Stratification of HPV-Positive Head and Neck Squamous Cell Carcinoma. PMID:31357501
Dramatic changes in gene expression in different forms of Crithidia fasciculata reveal potential mechanisms for insect-specific adhesion in kinetoplastid parasites. PMID:31356610
Identification and Application of Gene Expression Signatures Associated with Lifespan Extension. PMID:31353263
Circular RNAs are differentially expressed in prostate cancer and are potentially associated with resistance to enzalutamide. PMID:31341219
Anti-miRNA Oligonucleotide Therapy for Chondrosarcoma. PMID:31341031
L1TD1 - a prognostic marker for colon cancer. PMID:31337362
Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer. PMID:31336942
Cultivation and Transcriptional Analysis of a Canonical Nitrospira Under Stable Growth Conditions. PMID:31333593
The Pol IV largest subunit CTD quantitatively affects siRNA levels guiding RNA-directed DNA methylation. PMID:31329950
Data-driven characterization of molecular phenotypes across heterogeneous sample collections. PMID:31329928
AKAP6 and phospholamban colocalize and interact in HEK-293T cells and primary murine cardiomyocytes. PMID:31325238
Profiling microRNA expression in murine bone healing and non-union formation: Role of miR-140 during the early stage of bone healing. PMID:31323027
Identification and characterization of sexual dimorphism‑linked gene expression profile in hepatocellular carcinoma. PMID:31322260
mTORC1/AMPK responses define a core gene set for developmental cell fate switching. PMID:31319820
Transcriptional Regulation of the Glucose-6-Phosphate/Phosphate Translocator 2 Is Related to Carbon Exchange Across the Chloroplast Envelope. PMID:31316533
Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress. PMID:31316122
Density distribution of gene expression profiles and evaluation of using maximal information coefficient to identify differentially expressed genes. PMID:31314810
A Combined Transcriptomic and Genomic Analysis Identifies a Gene Signature Associated With the Response to Anti-TNF Therapy in Rheumatoid Arthritis. PMID:31312201
Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer. PMID:31312022
Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma. PMID:31310053
Long Noncoding RNA Expression Profile in BV2 Microglial Cells Exposed to Lipopolysaccharide. PMID:31309106
Anti-inflammatory nutrition with high protein attenuates cardiac and skeletal muscle alterations in a pulmonary arterial hypertension model. PMID:31308383
Clinical update on head and neck cancer: molecular biology and ongoing challenges. PMID:31308358
PRPF40A as a potential diagnostic and prognostic marker is upregulated in pancreatic cancer tissues and cell lines: an integrated bioinformatics data analysis. PMID:31303762
Inferring Regulatory Programs Governing Region Specificity of Neuroepithelial Stem Cells during Early Hindbrain and Spinal Cord Development. PMID:31302154
Retention of paternal DNA methylome in the developing zebrafish germline. PMID:31296860
Evaluating single-subject study methods for personal transcriptomic interpretations to advance precision medicine. PMID:31296218
MCF-7 as a Model for Functional Analysis of Breast Cancer Risk Variants. PMID:31292138
Integration of probabilistic regulatory networks into constraint-based models of metabolism with applications to Alzheimer's disease. PMID:31291905
Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions. PMID:31285548
Genome-scale metabolic model of the rat liver predicts effects of diet restriction. PMID:31285465
Surface PEGylation suppresses pulmonary effects of CuO in allergen-induced lung inflammation. PMID:31277695
Identification of diagnostic markers for major depressive disorder by cross-validation of data from whole blood samples. PMID:31275757
Gene coexpression network for trans-1,4-polyisoprene biosynthesis involving mevalonate and methylerythritol phosphate pathways in Eucommia ulmoides Oliver. PMID:31275023
Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. PMID:31271750
Estimation of Transcription Factor Activity in Knockdown Studies. PMID:31270369
Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors. PMID:31260032
L1000 Viewer: A Search Engine and Web Interface for the LINCS Data Repository. PMID:31258549
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking. PMID:31253831
Ethylene-mediated improvement in sucrose accumulation in ripening sugarcane involves increased sink strength. PMID:31253103
Inferring Interaction Networks From Multi-Omics Data. PMID:31249591
Identification of gene expression logical invariants in Arabidopsis. PMID:31245766
Ethylene causes transcriptomic changes in Synechocystis during phototaxis. PMID:31245714
Dark period transcriptomic and metabolic profiling of two diverse Eutrema salsugineum accessions. PMID:31245703
Cross-species complementation reveals conserved functions for EARLY FLOWERING 3 between monocots and dicots. PMID:31245666
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice. PMID:31240246
Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1). PMID:31239533
Pollination Type Recognition from a Distance by the Ovary Is Revealed Through a Global Transcriptomic Analysis. PMID:31238522
Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma. PMID:31236944
An Oncogenic Role for Four-Jointed Box 1 (FJX1) in Nasopharyngeal Carcinoma. PMID:31236144
Screening of Candida albicans GRACE library revealed a unique pattern of biofilm formation under repression of the essential gene ILS1. PMID:31235750
Axonal pathology in hPSC-based models of Parkinson's disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus. PMID:31235589
miR-26a-5p is a Stable Reference Gene for miRNA Studies in Chondrocytes from Developing Human Cartilage. PMID:31234552
Core regulon of the global anaerobic regulator Anr targets central metabolism functions in Pseudomonas species. PMID:31227753
Polymorphisms of the cryptochrome 2 and mitoguardin 2 genes are associated with the variation of lipid-related traits in Duroc pigs. PMID:31227735
Next-Generation Sequencing Reveals Increased Anti-oxidant Response and Ecdysone Signaling in STAT Supercompetitors in Drosophila. PMID:31227525
Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice. PMID:31222024
The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice. PMID:31221853
Genomic knockout of alms1 in zebrafish recapitulates Alström syndrome and provides insight into metabolic phenotypes. PMID:31220269
High similarity of IgG antibody profiles in blood and saliva opens opportunities for saliva based serology. PMID:31220138
BCScreen: A gene panel to test for breast carcinogenesis in chemical safety screening. PMID:31218268
MetaGxData: Clinically Annotated Breast, Ovarian and Pancreatic Cancer Datasets and their Use in Generating a Multi-Cancer Gene Signature. PMID:31217513
Pseudomonas donghuensis HYS virulence towards Caenorhabditis elegans is regulated by the Cbr/Crc system. PMID:31217473
Methylome-Wide Association Study in Peripheral White Blood Cells Focusing on Central Obesity and Inflammation. PMID:31212707
Carriage of Shiga toxin phage profoundly affects Escherichia coli gene expression and carbon source utilization. PMID:31208335
Insulin Sensitivity Is Associated with Lipoprotein Lipase (LPL) and Catenin Delta 2 (CTNND2) DNA Methylation in Peripheral White Blood Cells in Non-Diabetic Young Women. PMID:31208038
DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes. PMID:31206562
Multi omics analysis of fibrotic kidneys in two mouse models. PMID:31201317
SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses. PMID:31201239
Dissecting the Prognostic Significance and Functional Role of Progranulin in Chronic Lymphocytic Leukemia. PMID:31200555
Comprehensive bioinformatics analysis of trabecular meshwork gene expression data to unravel the molecular pathogenesis of primary open-angle glaucoma. PMID:31197946
Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. PMID:31194736
Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells. PMID:31191614
Identification of novel biomarkers and candidate small molecule drugs in non-small-cell lung cancer by integrated microarray analysis. PMID:31190860
Overexpression of the MYB29 transcription factor affects aliphatic glucosinolate synthesis in Brassica oleracea. PMID:31190320
Cell Cycle-Dependent Regulation and Function of ARGONAUTE1 in Plants. PMID:31189739
Specialized eRpL22 paralogue-specific ribosomes regulate specific mRNA translation in spermatogenesis in Drosophila melanogaster. PMID:31188709
Molecular Signature of Asthma-Enhanced Sensitivity to CuO Nanoparticle Aerosols from 3D Cell Model. PMID:31188557
miR-17-92 and miR-106b-25 clusters regulate beta cell mitotic checkpoint and insulin secretion in mice. PMID:31187215
Dissecting the Stromal Signaling and Regulation of Myeloid Cells and Memory Effector T Cells in Pancreatic Cancer. PMID:31186314
Annotation and Expression of IDN2-like and FDM-like Genes in Sexual and Aposporous Hypericum perforatum L. accessions. PMID:31181659
Genetic resistance to DEHP-induced transgenerational endocrine disruption. PMID:31181066
Ovule Gene Expression Analysis in Sexual and Aposporous Apomictic Hypericum perforatum L. (Hypericaceae) Accessions. PMID:31178879
The role of TNF-α in chordoma progression and inflammatory pathways. PMID:31175552
Identification of microRNAs associated with the aggressiveness of prolactin pituitary tumors using bioinformatic analysis. PMID:31173251
Identification of key candidate genes involved in melanoma metastasis. PMID:31173190
Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages. PMID:31172864
Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PMID:31170154
Tertiary lymphoid structures in the choroid plexus in neuropsychiatric lupus. PMID:31167973
Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis. PMID:31167948
Gene set enrichment for reproducible science: comparison of CERNO and eight other algorithms. PMID:31165139
Toxicity mechanisms of ZnO UV-filters used in sunscreens toward the model cyanobacteria Synechococcus elongatus PCC 7942. PMID:31161548
RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes. PMID:31158233
PRC2-Mediated H3K27me3 Contributes to Transcriptional Regulation of FIT-Dependent Iron Deficiency Response. PMID:31156682
Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice. PMID:31150625
An overview of publicly available patient-centered prostate cancer datasets. PMID:31143673
Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. PMID:31142855
Map and model-moving from observation to prediction in toxicogenomics. PMID:31140561
Cytochrome P450 Monooxygenase-Mediated Metabolic Utilization of Benzo[a]Pyrene by Aspergillus Species. PMID:31138742
Proton-irradiated breast cells: molecular points of view. PMID:31135901
Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells. PMID:31134094
Microhomologies are prevalent at Cas9-induced larger deletions. PMID:31127293
Plasticity of intestinal gene expression profile signatures reflected by nutritional interventions in piglets. PMID:31122193
MultiPLIER: A Transfer Learning Framework for Transcriptomics Reveals Systemic Features of Rare Disease. PMID:31121115
Acid-Sensitive Ion Channels Are Expressed in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. PMID:31119982
Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4+ memory T cells. PMID:31118448
Transcriptomic responses to diet quality and viral infection in Apis mellifera. PMID:31117959
Cold acclimation triggers major transcriptional changes in Drosophila suzukii. PMID:31117947
The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21. PMID:31116991
ChEA3: transcription factor enrichment analysis by orthogonal omics integration. PMID:31114921
Differentially and Co-expressed Genes in Embryo, Germ-Line and Somatic Tissues of Tribolium castaneum. PMID:31113821
GREIN: An Interactive Web Platform for Re-analyzing GEO RNA-seq Data. PMID:31110304
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. PMID:31110176
The Placental Atlas Tool (PAT): A collaborative research and discovery platform for the placental research community. PMID:31103066
Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions. PMID:31101817
Identification of three subtypes of triple-negative breast cancer with potential therapeutic implications. PMID:31101122
CiliaCarta: An integrated and validated compendium of ciliary genes. PMID:31095607
Unbiased Boolean analysis of public gene expression data for cell cycle gene identification. PMID:31091168
GIDB: a knowledge database for the automated curation and multidimensional analysis of molecular signatures in gastrointestinal cancer. PMID:31089686
Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection. PMID:31088926
Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment. PMID:31088847
A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome. PMID:31088495
Banana (Musa acuminata) transcriptome profiling in response to rhizobacteria: Bacillus amyloliquefaciens Bs006 and Pseudomonas fluorescens Ps006. PMID:31088352
Snf2 controls pulcherriminic acid biosynthesis and antifungal activity of the biocontrol yeast Metschnikowia pulcherrima. PMID:31081214
Strain-selective efficacy of sacubitril/valsartan on carotid fibrosis in response to injury in two inbred mouse strains. PMID:31077344
AKIRIN1: A Potential New Reference Gene in Human Natural Killer Cells and Granulocytes in Sepsis. PMID:31075840
Transcriptome and physiological analyses for revealing genes involved in wheat response to endoplasmic reticulum stress. PMID:31072347
Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name. PMID:31071451
A miR-206 regulated gene landscape enhances mammary epithelial differentiation. PMID:31069797
Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimer's Disease. PMID:31068785
scNPF: an integrative framework assisted by network propagation and network fusion for preprocessing of single-cell RNA-seq data. PMID:31068142
The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming. PMID:31067451
Integrative proteomics reveals an increase in non-degradative ubiquitylation in activated CD4+ T cells. PMID:31061531
The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin. PMID:31059533
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation. PMID:31048683
Mouse models and strain-dependency of Chédiak-Higashi syndrome-associated neurologic dysfunction. PMID:31043676
Characterizing novel olfactory receptors expressed in the murine renal cortex. PMID:31042061
Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells. PMID:31039138
Associations between Maternal Tobacco Smoke Exposure and the Cord Blood [Formula: see text] DNA Methylome. PMID:31039056
Specific chromatin changes mark lateral organ founder cells in the Arabidopsis inflorescence meristem. PMID:31037302
Cyclin C Regulated Oxidative Stress Responsive Transcriptome in Mus musculus Embryonic Fibroblasts. PMID:31036676
Robust pathway-based multi-omics data integration using directed random walks for survival prediction in multiple cancer studies. PMID:31036036
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination. PMID:31033435
A Novel Joint Gene Set Analysis Framework Improves Identification of Enriched Pathways in Cross Disease Transcriptomic Analysis. PMID:31031796
An Open Science Approach to Artificial Intelligence in Healthcare. PMID:31022753
Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi. PMID:31020039
Two putative MmpL homologs contribute to antimicrobial resistance and nephropathy of enterohemorrhagic E. coli O157:H7. PMID:31019555
Atlas of RNA sequencing profiles for normal human tissues. PMID:31015567
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. PMID:31015400
Ancestry patterns inferred from massive RNA-seq data. PMID:31010885
A Mobile Auxin Signal Connects Temperature Sensing in Cotyledons with Growth Responses in Hypocotyls. PMID:31000634
OCT4 and PAX6 determine the dual function of SOX2 in human ESCs as a key pluripotent or neural factor. PMID:30999923
Comparison of multi-tissue aging between human and mouse. PMID:30996271
Development and characterisation of acquired radioresistant breast cancer cell lines. PMID:30987655
Variants in KIAA0825 underlie autosomal recessive postaxial polydactyly. PMID:30982135
Sensitive Quantitative Proteomics of Human Hematopoietic Stem and Progenitor Cells by Data-independent Acquisition Mass Spectrometry. PMID:30975897
Identification of Target Genes at Juvenile Idiopathic Arthritis GWAS Loci in Human Neutrophils. PMID:30972099
Gene expression shifts in yellow-bellied marmots prior to natal dispersal. PMID:30971856
Functioning of Mycobacterial Heat Shock Repressors Requires the Master Virulence Regulator PhoP. PMID:30962357
FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex. PMID:30962207
Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism. PMID:30957416
Identification of common highly expressed genes of Salmonella Enteritidis by in silico prediction of gene expression and in vitro transcriptomic analysis. PMID:30953073
Influenza A Reinfection in Sequential Human Challenge: Implications for Protective Immunity and "Universal" Vaccine Development. PMID:30953061
exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids. PMID:30951672
PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data. PMID:30951143
Multi-omics Analysis Reveals Sequential Roles for ABA during Seed Maturation. PMID:30948555
The role of the GATA transcription factor AreB in regulation of nitrogen and carbon metabolism in Aspergillus nidulans. PMID:30939206
Gene set meta-analysis with Quantitative Set Analysis for Gene Expression (QuSAGE). PMID:30939133
Transcriptome Sequence of Antibiotic-Treated Pseudomonas aeruginosa. PMID:30938705
Elevated Plasma microRNA-105-5p Level in Patients With Idiopathic Parkinson's Disease: A Potential Disease Biomarker. PMID:30936821
Progesterone Receptor Attenuates STAT1-Mediated IFN Signaling in Breast Cancer. PMID:30936295
Transcriptional and Chemical Changes in Soybean Leaves in Response to Long-Term Aphid Colonization. PMID:30930925
Accumulating Transcriptome Drift Precedes Cell Aging in Human Umbilical Cord-Derived Mesenchymal Stromal Cells Serially Cultured to Replicative Senescence. PMID:30924318
A Pathway-Based Strategy to Identify Biomarkers for Lung Cancer Diagnosis and Prognosis. PMID:30923439
Characterization of the European Sea Bass (Dicentrarchus labrax) Gonadal Transcriptome During Sexual Development. PMID:30919121
Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway. PMID:30915071
let-7 coordinates the transition to adulthood through a single primary and four secondary targets. PMID:30910805
Repression of Germline Genes in Caenorhabditis elegans Somatic Tissues by H3K9 Dimethylation of Their Promoters. PMID:30910798
Advancing Computational Toxicology in the Big Data Era by Artificial Intelligence: Data-Driven and Mechanism-Driven Modeling for Chemical Toxicity. PMID:30907586
Integrated transcriptome interactome study of oncogenes and tumor suppressor genes in breast cancer. PMID:30906836
Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans. PMID:30897162
Conformational Engineering of HIV-1 Env Based on Mutational Tolerance in the CD4 and PG16 Bound States. PMID:30894475
Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade. PMID:30886604
A Systems Vaccinology Approach Reveals the Mechanisms of Immunogenic Responses to Hantavax Vaccination in Humans. PMID:30886186
Identification of Important Effector Proteins in the FOXJ1 Transcriptional Network Associated With Ciliogenesis and Ciliary Function. PMID:30881373
DDOT: A Swiss Army Knife for Investigating Data-Driven Biological Ontologies. PMID:30878356
Copper transporter COPT5 participates in the crosstalk between vacuolar copper and iron pools mobilisation. PMID:30874615
Analysis of differential gene expression and alternative splicing is significantly influenced by choice of reference genome. PMID:30872414
Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies. PMID:30871144
Clonal analyses of refractory testicular germ cell tumors. PMID:30870501
Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network. PMID:30867892
Bioinformatic exploration of OLFML2B overexpression in gastric cancer base on multiple analyzing tools. PMID:30866865
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis. PMID:30862866
Highly Resolved Systems Biology to Dissect the Etioplast-to-Chloroplast Transition in Tobacco Leaves. PMID:30862726
Regulatory network reconstruction of five essential microRNAs for survival analysis in breast cancer by integrating miRNA and mRNA expression datasets. PMID:30859354
Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma. PMID:30858547
Transcriptional Analysis Shows a Robust Host Response to Toxoplasma gondii during Early and Late Chronic Infection in Both Male and Female Mice. PMID:30858341
Identification of Novel Interaction Partners of Ets-1: Focus on DNA Repair. PMID:30857266
The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus. PMID:30852652
Leveraging Big Data to Transform Drug Discovery. PMID:30848458
Automated exploration of gene ontology term and pathway networks with ClueGO-REST. PMID:30847467
Linking Terpene Synthases to Sesquiterpene Metabolism in Grapevine Flowers. PMID:30846994
A SIR-independent role for cohesin in subtelomeric silencing and organization. PMID:30842278
A new computational drug repurposing method using established disease-drug pair knowledge. PMID:30840053
Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. PMID:30837897
Folate Repletion after Deficiency Induces Irreversible Genomic and Transcriptional Changes in Human Papillomavirus Type 16 (HPV16)-Immortalized Human Keratinocytes. PMID:30836646
Minor Isozymes Tailor Yeast Metabolism to Carbon Availability. PMID:30834327
The Epstein-Barr virus EBNA1 protein modulates the alternative splicing of cellular genes. PMID:30832682
Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1. PMID:30827514
Targetome analysis of chaperone-mediated autophagy in cancer cells. PMID:30821613
Don't brush off buccal data heterogeneity. PMID:30821575
Silicon supply affects the root transcriptome of Brassica napus L. PMID:30820649
Comparing DNA methylation profiles in saliva and intestinal mucosa. PMID:30819108
Rapalog resistance is associated with mesenchymal-type changes in Tsc2-null cells. PMID:30816188
Clinical and research applications of a brain tumor tissue bank in the age of precision medicine. PMID:30816054
FAIRness and Usability for Open-access Omics Data Systems. PMID:30815061
The analysis of a time-course transcriptome profile by systems biology approaches reveals key molecular processes in acute kidney injury. PMID:30815016
hsa-miR-301a- and SOX10-dependent miRNA-TF-mRNA regulatory circuits in breast cancer. PMID:30814872
Loss of Stromal Galectin-1 Enhances Multiple Myeloma Development: Emphasis on a Role in Osteoclasts. PMID:30813402
Podocyte-specific expression of Cre recombinase promotes glomerular basement membrane thickening. PMID:30810063
NADH Dehydrogenases in Pseudomonas aeruginosa Growth and Virulence. PMID:30804898
Circadian regulation in human white adipose tissue revealed by transcriptome and metabolic network analysis. PMID:30804433
Differential Gene Expression Patterns of Yersinia pestis and Yersinia pseudotuberculosis during Infection and Biofilm Formation in the Flea Digestive Tract. PMID:30801031
The prognostic landscape of interactive biological processes presents treatment responses in cancer. PMID:30799199
Circular RNAs are temporospatially regulated throughout development and ageing in the rat. PMID:30796328
Correlation-adjusted regression survival scores for high-dimensional variable selection. PMID:30793795
Epigenome-wide association study in peripheral white blood cells involving insulin resistance. PMID:30792424
Physiological and Transcriptional Responses in Weaned Piglets Fed Diets with Varying Phosphorus and Calcium Levels. PMID:30791512
Global transcriptional regulation of innate immunity by ATF-7 in C. elegans. PMID:30789901
Genetic programming of macrophages generates an in vitro model for the human erythroid island niche. PMID:30787325
Identification of Potential Key Genes and Pathways in Early-Onset Colorectal Cancer Through Bioinformatics Analysis. PMID:30786729
Analysis of the mRNAs in Spores of Bacillus subtilis. PMID:30782632
The Impact of the Wheat Rht-B1b Semi-Dwarfing Allele on Photosynthesis and Seed Development Under Field Conditions. PMID:30778362
Comparative Transcriptomics Between Zebrafish and Mammals: A Roadmap for Discovery of Conserved and Unique Signaling Pathways in Physiology and Disease. PMID:30775367
Unveiling the Link Between Inflammation and Adaptive Immunity in Breast Cancer. PMID:30761130
CD56dim CD16- Natural Killer Cell Profiling in Melanoma Patients Receiving a Cancer Vaccine and Interferon-α. PMID:30761123
Isoprene Acts as a Signaling Molecule in Gene Networks Important for Stress Responses and Plant Growth. PMID:30760638
Extrachloroplastic PP7L Functions in Chloroplast Development and Abiotic Stress Tolerance. PMID:30760637
Mapping Metabolic Events in the Cancer Cell Cycle Reveals Arginine Catabolism in the Committed SG2M Phase. PMID:30759381
IDO1 inhibition potentiates vaccine-induced immunity against pancreatic adenocarcinoma. PMID:30747725
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation. PMID:30745319
Identification of potential blood biomarkers for Parkinson's disease by gene expression and DNA methylation data integration analysis. PMID:30744671
The genetic requirements of fatty acid import by Mycobacterium tuberculosis within macrophages. PMID:30735132
Analysis of long non-coding RNA and mRNA expression in bovine macrophages brings up novel aspects of Mycobacterium avium subspecies paratuberculosis infections. PMID:30733564
Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A. PMID:30733433
Data mining for mutation-specific targets in acute myeloid leukemia. PMID:30728456
An experimental genetically attenuated live vaccine to prevent transmission of Toxoplasma gondii by cats. PMID:30728393
The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis. PMID:30728374
Shambhala: a platform-agnostic data harmonizer for gene expression data. PMID:30727942
Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma. PMID:30723586
Comparison of RNA-Seq and Microarray Gene Expression Platforms for the Toxicogenomic Evaluation of Liver From Short-Term Rat Toxicity Studies. PMID:30723492
Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages. PMID:30723476
Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits. PMID:30723160
Mucor circinelloides Thrives inside the Phagosome through an Atf-Mediated Germination Pathway. PMID:30723131
Characterisation and validation of Mel38; A multi-tissue microRNA signature of cutaneous melanoma. PMID:30721246
Bioinformatic analysis of next‑generation sequencing data to identify dysregulated genes in fibroblasts of idiopathic pulmonary fibrosis. PMID:30720061
Combining data from TCGA and GEO databases and reverse transcription quantitative PCR validation to identify gene prognostic markers in lung cancer. PMID:30718962
Inferring Gene Regulatory Networks from a Population of Yeast Segregants. PMID:30718595
Mesoscale modeling reveals formation of an epigenetically driven HOXC gene hub. PMID:30718394
Latent network-based representations for large-scale gene expression data analysis. PMID:30717663
Temporal Change of Extracellular Matrix during Vein Arterialization Remodeling in Rats. PMID:30717394
Network-based identification of critical regulators as putative drivers of human cleft lip. PMID:30704473
SMAGEXP: a galaxy tool suite for transcriptomics data meta-analysis. PMID:30698691
Loss of CRWN Nuclear Proteins Induces Cell Death and Salicylic Acid Defense Signaling. PMID:30696746
Venous identity requires BMP signalling through ALK3. PMID:30692543
Assessment of weighted topological overlap (wTO) to improve fidelity of gene co-expression networks. PMID:30691386
X-ray irradiation induces subtle changes in the genome-wide distribution of DNA hydroxymethylation with opposing trends in genic and intergenic regions. PMID:30691379
Hypoxia Is Not a Main Stress When Mycobacterium tuberculosis Is in a Dormancy-Like Long-Chain Fatty Acid Environment. PMID:30687646
Drug repositioning for dengue haemorrhagic fever by integrating multiple omics analyses. PMID:30679503
Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli. PMID:30677026
Identification of Blood Biomarkers for Alzheimer's Disease Through Computational Prediction and Experimental Validation. PMID:30671019
Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster. PMID:30670478
CMEP: a database for circulating microRNA expression profiling. PMID:30668638
IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis. PMID:30666255
Comparative transcriptomic analysis unveils interactions between the regulatory CarS protein and light response in Fusarium. PMID:30665350
Identification of key genes and pathways involved in microsatellite instability in colorectal cancer. PMID:30664178
EFNB2 acts as the target of miR-557 to facilitate cell proliferation, migration and invasion in pancreatic ductal adenocarcinoma by bioinformatics analysis and verification. PMID:30662604
Illuminating spatial A-to-I RNA editing signatures within the Drosophila brain. PMID:30659150
Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-κB repressing factor. PMID:30659143
Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age. PMID:30654924
Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells. PMID:30654593
p.E95K mutation in Indian hedgehog causing brachydactyly type A1 impairs IHH/Gli1 downstream transcriptional regulation. PMID:30651074
Restructured GEO: restructuring Gene Expression Omnibus metadata for genome dynamics analysis. PMID:30649296
MLPA is a practical and complementary alternative to CMA for diagnostic testing in patients with autism spectrum disorders and identifying new candidate CNVs associated with autism. PMID:30647996
Systems Biology Approach to Identify Novel Genomic Determinants for Pancreatic Cancer Pathogenesis. PMID:30644396
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. PMID:30643292
TULP3: A potential biomarker in colorectal cancer? PMID:30640939
HSP90 inhibitor geldanamycin reverts IL-13- and IL-17-induced airway goblet cell metaplasia. PMID:30640172
Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding. PMID:30633912
Computational translation of genomic responses from experimental model systems to humans. PMID:30629591
Meta-analysis of gene expression profiles in long-term non-progressors infected with HIV-1. PMID:30626383
Transcriptomic profiles of tissues from rats treated with anticancer drug combinations. PMID:30620345
Reciprocal control of motility and biofilm formation by the PdhS2 two-component sensor kinase of Agrobacterium tumefaciens. PMID:30620265
HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways. PMID:30619338
Iron Regulation in Clostridioides difficile. PMID:30619231
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue. PMID:30613869
lncRNA-based study of epigenetic regulations in diabetic peripheral neuropathy. PMID:30607320
Re-annotation of eight Drosophila genomes. PMID:30599046
An internal ribosome entry site in the coding region of tyrosyl-DNA phosphodiesterase 2 drives alternative translation start. PMID:30593505
Modeling human prostate cancer progression in vitro. PMID:30590461
Low STYK1 expression indicates poor prognosis in gastric cancer. PMID:30584361
Camphor white oil induces tumor regression through cytotoxic T cell-dependent mechanisms. PMID:30582219
MeDEStrand: an improved method to infer genome-wide absolute methylation levels from DNA enrichment data. PMID:30577750
Impaired immune surveillance accelerates accumulation of senescent cells and aging. PMID:30575733
Downregulation of the Vitamin D Receptor Regulated Gene Set in the Hippocampus After MDMA Treatment. PMID:30559663
RNA⁻Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics. PMID:30558267
Factor cooperation for chromosome discrimination in Drosophila. PMID:30541149
Identification of molecular signatures of cystic fibrosis disease status with plasma-based functional genomics. PMID:30540547
Aberrantly expressed long noncoding RNAs and genes in Parkinson's disease. PMID:30538480
A transcriptomics analysis of the Tbx5 paralogues in zebrafish. PMID:30532148
LCE: an open web portal to explore gene expression and clinical associations in lung cancer. PMID:30532070
CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development. PMID:30531840
A Serum-Induced Transcriptome and Serum Cytokine Signature Obtained at Diagnosis Correlates with the Development of Early Pancreatic Ductal Adenocarcinoma Metastasis. PMID:30530849
Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response. PMID:30530734
SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice. PMID:30519364
Danger signals activate a putative innate immune system during regeneration in a filamentous fungus. PMID:30500812
Genome-wide identification of RETINOBLASTOMA RELATED 1 binding sites in Arabidopsis reveals novel DNA damage regulators. PMID:30500810
Tracking microRNA Processing Signals by Degradome Sequencing Data Analysis. PMID:30487815
Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium. PMID:30487180
PNPase is involved in the coordination of mRNA degradation and expression in stationary phase cells of Escherichia coli. PMID:30486791
Relation between Biofilm and Virulence in Vibrio tapetis: A Transcriptomic Study. PMID:30486310
SkeletalVis: an exploration and meta-analysis data portal of cross-species skeletal transcriptomics data. PMID:30481257
Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer's Disease. PMID:30480234
Prediction of plant-derived xenomiRs from plant miRNA sequences using random forest and one-dimensional convolutional neural network models. PMID:30477446
Identifying cancer-related microRNAs based on subpathways. PMID:30472691
Network Pharmacology to Unveil the Biological Basis of Health-Strengthening Herbal Medicine in Cancer Treatment. PMID:30469422
Differential expression of heat shock and floral regulatory genes in pseudocarpel initials of mantled female inflorescences from Elaeis guineensis Jacq. PMID:30467592
Human Prolactinoma: A View of Protein-Protein Interaction Pattern. PMID:30464775
STE20/PAKA Protein Kinase Gene Releases an Autoinhibitory Domain through Pre-mRNA Alternative Splicing in the Dermatophyte Trichophyton rubrum. PMID:30463281
From sequencing data to gene functions: co-functional network approaches. PMID:30460054
A data citation roadmap for scientific publishers. PMID:30457573
RNase E cleavage shapes the transcriptome of Rhodobacter sphaeroides and strongly impacts phototrophic growth. PMID:30456366
RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs database. PMID:30453895
BioJupies: Automated Generation of Interactive Notebooks for RNA-Seq Data Analysis in the Cloud. PMID:30447998
Screening and clinical significance of tumor markers in head and neck squamous cell carcinoma through bioinformatics analysis. PMID:30431092
Identification of hub genes with diagnostic values in pancreatic cancer by bioinformatics analyses and supervised learning methods. PMID:30428899
Comprehensive bioinformatics analysis identifies several potential diagnostic markers and potential roles of cyclin family members in lung adenocarcinoma. PMID:30425528
Deoxynivalenol Affects Cell Metabolism and Increases Protein Biosynthesis in Intestinal Porcine Epithelial Cells (IPEC-J2): DON Increases Protein Biosynthesis. PMID:30423940
Single cell network analysis with a mixture of Nested Effects Models. PMID:30423100
Conditional generative adversarial network for gene expression inference. PMID:30423066
A Comparison of the TempO-Seq S1500+ Platform to RNA-Seq and Microarray Using Rat Liver Mode of Action Samples. PMID:30420870
Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically-relevant faecal environment, with implications for pathogenicity. PMID:30420658
C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD). PMID:30419069
Stemformatics: visualize and download curated stem cell data. PMID:30407577
Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD. PMID:30406125
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. PMID:30405245
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. PMID:30404662
Bayesian variable selection for parametric survival model with applications to cancer omics data. PMID:30400837
Enabling precision medicine in neonatology, an integrated repository for preterm birth research. PMID:30398470
Effects of simulated microgravity on the expression profiles of RNA during osteogenic differentiation of human bone marrow mesenchymal stem cells. PMID:30397970
FAM92A Underlies Nonsyndromic Postaxial Polydactyly in Humans and an Abnormal Limb and Digit Skeletal Phenotype in Mice. PMID:30395363
Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans. PMID:30395284
PlantPAN3.0: a new and updated resource for reconstructing transcriptional regulatory networks from ChIP-seq experiments in plants. PMID:30395277
Profiling Immune Escape in Hodgkin's and Diffuse large B-Cell Lymphomas Using the Transcriptome and Immunostaining. PMID:30384489
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq. PMID:30383866
New miRNA Signature Heralds Human NK Cell Subsets at Different Maturation Steps: Involvement of miR-146a-5p in the Regulation of KIR Expression. PMID:30374356
Deep sequencing and miRNA profiles in alcohol-induced neuroinflammation and the TLR4 response in mice cerebral cortex. PMID:30374194
ViBrism DB: an interactive search and viewer platform for 2D/3D anatomical images of gene expression and co-expression networks. PMID:30371824
Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data. PMID:30371680
RNA-Seq-Based Analysis Reveals Heterogeneity in Mature 16S rRNA 3' Termini and Extended Anti-Shine-Dalgarno Motifs in Bacterial Species. PMID:30355764
wTO: an R package for computing weighted topological overlap and a consensus network with integrated visualization tool. PMID:30355288
Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor. PMID:30353164
Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells. PMID:30352569
Dietary fibers inhibit obesity in mice, but host responses in the cecum and liver appear unrelated to fiber-specific changes in cecal bacterial taxonomic composition. PMID:30349136
Gene expression profiling in a mouse model of Dravet syndrome. PMID:30347190
Prediction of Target Genes and Pathways Associated With Cetuximab Insensitivity in Colorectal Cancer. PMID:30336768
Single-Cell RNA Sequencing Reveals Novel Markers of Male Pituitary Stem Cells and Hormone-Producing Cell Types. PMID:30335147
A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas. PMID:30335132
Comparative Study on Alternative Splicing in Human Fungal Pathogens Suggests Its Involvement During Host Invasion. PMID:30333805
Genome organization and DNA accessibility control antigenic variation in trypanosomes. PMID:30333624
Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis. PMID:30333037
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex. PMID:30327463
sEst: Accurate Sex-Estimation and Abnormality Detection in Methylation Microarray Data. PMID:30326623
Effects of rheumatoid arthritis associated transcriptional changes on osteoclast differentiation network in the synovium. PMID:30324023
A comparative study of endoderm differentiation in humans and chimpanzees. PMID:30322406
Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AIT. PMID:30318182
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids. PMID:30311909
Translocated duplication of a targeted chromosomal segment enhances gene expression at the duplicated site and results in phenotypic changes in Aspergillus oryzae. PMID:30305913
Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling. PMID:30300589
Identification of gene expression predictors of occupational benzene exposure. PMID:30300410
Multiomics approach reveals metabolic changes in the heart at birth. PMID:30300011
Two Regulators, PA3898 and PA2100, Modulate the Pseudomonas aeruginosa Multidrug Resistance MexAB-OprM and EmrAB Efflux Pumps and Biofilm Formation. PMID:30297364
Proteome and transcriptome profiling of equine myofibrillar myopathy identifies diminished peroxiredoxin 6 and altered cysteine metabolic pathways. PMID:30289745
Early isolated V-lesion may not truly represent rejection of the kidney allograft. PMID:30287520
Identification of key genes involved in the phenotypic alterations of res (restored cell structure by salinity) tomato mutant and its recovery induced by salt stress through transcriptomic analysis. PMID:30285698
Exposure to childhood abuse is associated with human sperm DNA methylation. PMID:30279435
Increased EXT1 gene copy number correlates with increased mRNA level predicts short disease-free survival in hepatocellular carcinoma without vascular invasion. PMID:30278583
New insights into the cellular temporal response to proteostatic stress. PMID:30272558
Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease. PMID:30270042
Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs. PMID:30269950
Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. PMID:30266981
Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogramming of glutamine metabolism. PMID:30266295
Candida albicans Sfl1/Sfl2 regulatory network drives the formation of pathogenic microcolonies. PMID:30252918
Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response. PMID:30250647
Fenretinide targeting of human colon cancer sphere cells through cell cycle regulation and stress-responsive activities. PMID:30250604
Comprehensive analysis of gene expression profiles associated with proliferative diabetic retinopathy. PMID:30250524
Robustness by intrinsically disordered C-termini and translational readthrough. PMID:30247639
Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations. PMID:30241495
Zingerone Suppresses Tumor Development through Decreasing Cyclin D1 Expression and Inducing Mitotic Arrest. PMID:30235818
Overexpression of an auxin receptor OsAFB6 significantly enhanced grain yield by increasing cytokinin and decreasing auxin concentrations in rice panicle. PMID:30232356
Mannose Alters Gut Microbiome, Prevents Diet-Induced Obesity, and Improves Host Metabolism. PMID:30231992
Subgroup-specific immune and stromal microenvironment in medulloblastoma. PMID:30228931
Integrated Genome-Wide Analysis of Gene Expression and DNA Copy Number Variations Highlights Stem Cell-Related Pathways in Small Cell Esophageal Carcinoma. PMID:30228821
Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease. PMID:30228239
Longitudinal transcriptomic characterization of the immune response to acute hepatitis C virus infection in patients with spontaneous viral clearance. PMID:30222771
The topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates. PMID:30222730
Inhibition of neogenin fosters resolution of inflammation and tissue regeneration. PMID:30222138
Effects of hydroxyurea on CNV induction in the mouse germline. PMID:30218578
Assortment of Flowering Time and Immunity Alleles in Natural Arabidopsis thaliana Populations Suggests Immunity and Vegetative Lifespan Strategies Coevolve. PMID:30215800
Systematic Analysis of Gene Expression Profiles Controlled by hnRNP Q and hnRNP R, Two Closely Related Human RNA Binding Proteins Implicated in mRNA Processing Mechanisms. PMID:30214903
Identification of a novel gene fusion in ALT positive osteosarcoma. PMID:30214690
PAX5A and PAX5B isoforms are both efficient to drive B cell differentiation. PMID:30214688
Distinct prognostic values of mRNA expression of glutathione peroxidases in non-small cell lung cancer. PMID:30214294
Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes. PMID:30214008
Polarized Entry of Human Parechoviruses in the Airway Epithelium. PMID:30211126
Regional Differences in Airway Epithelial Cells Reveal Tradeoff between Defense against Oxidative Stress and Defense against Rhinovirus. PMID:30208323
Computational prediction of changes in brain metabolic fluxes during Parkinson's disease from mRNA expression. PMID:30208076
Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes. PMID:30206180
Genotoxic, Metabolic, and Oxidative Stresses Regulate the RNA Repair Operon of Salmonella enterica Serovar Typhimurium. PMID:30201777
An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos. PMID:30201514
Elevated expression of NFE2L3 predicts the poor prognosis of pancreatic cancer patients. PMID:30196752
Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization With Recombinant Attenuated Salmonella Vaccine Strains. PMID:30186843
A Microarray Study of Articular Cartilage in Relation to Obesity and Severity of Knee Osteoarthritis. PMID:30173558
Feasibility of developing reliable gene expression modules from FFPE derived RNA profiled on Affymetrix arrays. PMID:30169535
Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells. PMID:30165855
Post-transcriptional gene regulation by an Hfq-independent small RNA in Caulobacter crescentus. PMID:30165530
Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens. PMID:30158907
Differentially expressed proteins in positive versus negative HNSCC lymph nodes. PMID:30157864
Harnessing the biological complexity of Big Data from LINCS gene expression signatures. PMID:30157183
A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas. PMID:30145115
Fate-restricted retinal progenitor cells adopt a molecular profile and spatial position distinct from multipotent progenitor cells. PMID:30145104
Construction and analysis of mRNA, miRNA, lncRNA, and TF regulatory networks reveal the key genes associated with prostate cancer. PMID:30138363
Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-α, IL-1β, and IFN-γ. PMID:30136410
Plasma microRNA markers of upper limb recovery following human stroke. PMID:30135469
Transcriptional targeting of oncogene addiction in medullary thyroid cancer. PMID:30135308
Prediction of key genes and pathways involved in trastuzumab-resistant gastric cancer. PMID:30134903
Identification of protein complexes associated with myocardial infarction using a bioinformatics approach. PMID:30132549
Dissecting the expression landscape of mitochondrial genes in lung squamous cell carcinoma and lung adenocarcinoma. PMID:30128019
Identification of genes that predict the biochemical recurrence of prostate cancer. PMID:30127947
Screening and identification of key biomarkers in bladder carcinoma: Evidence from bioinformatics analysis. PMID:30127900
Profiles of immune infiltration in colorectal cancer and their clinical significant: A gene expression-based study. PMID:30117315
Detecting Differentially Variable MicroRNAs via Model-Based Clustering. PMID:30116730
A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation. PMID:30115738
Comprehensive integrated analysis of gene expression datasets identifies key anti-cancer targets in different stages of breast cancer. PMID:30112036
QsRNA-seq: a method for high-throughput profiling and quantifying small RNAs. PMID:30107842
Revealing a human p53 universe. PMID:30107566
Machine Learning Based Toxicity Prediction: From Chemical Structural Description to Transcriptome Analysis. PMID:30103448
The effect of Tmem135 overexpression on the mouse heart. PMID:30102730
AMPK activation negatively regulates GDAP1, which influences metabolic processes and circadian gene expression in skeletal muscle. PMID:30093355
JAK-STAT signaling is activated in the kidney and peripheral blood cells of patients with focal segmental glomerulosclerosis. PMID:30093081
Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease. PMID:30089721
BART: bioinformatics array research tool. PMID:30089462
Reconstruction of the Protein-Protein Interaction Network for Protein Complexes Identification by Walking on the Protein Pair Fingerprints Similarity Network. PMID:30087694
Myc and ChREBP transcription factors cooperatively regulate normal and neoplastic hepatocyte proliferation in mice. PMID:30087120
Consensus on Molecular Subtypes of High-Grade Serous Ovarian Carcinoma. PMID:30084834
Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature. PMID:30083721
Sensory Neuron Diversity in the Inner Ear Is Shaped by Activity. PMID:30078709
Improving knowledge on the activation of bone marrow fibroblasts in MGUS and MM disease through the automatic extraction of genes via a nonnegative matrix factorization approach on gene expression profiles. PMID:30075788
Douglas-Fir ( Pseudotsuga menziesii (Mirb.) Franco) Transcriptome Profile Changes Induced by Diesel Emissions Generated with CeO2 Nanoparticle Fuel Borne Catalyst. PMID:30075627
Combinatorial Approaches to Viral Attenuation. PMID:30073203
Gene expression analysis indicates reduced memory and cognitive functions in the hippocampus and increase in synaptic reorganization in the frontal cortex 3 weeks after MDMA administration in Dark Agouti rats. PMID:30071829
Parental high dietary arachidonic acid levels modulated the hepatic transcriptome of adult zebrafish (Danio rerio) progeny. PMID:30070994
Male increase in brain gene expression variability is linked to genetic risk for schizophrenia. PMID:30068996
PAK2-c-Myc-PKM2 axis plays an essential role in head and neck oncogenesis via regulating Warburg effect. PMID:30068946
Cardiovascular progenitor cells cultured aboard the International Space Station exhibit altered developmental and functional properties. PMID:30062101
Pattern of DNA Methylation in Daphnia: Evolutionary Perspective. PMID:30060190
The CRISPR/Cas system in Neisseria meningitidis affects bacterial adhesion to human nasopharyngeal epithelial cells. PMID:30059276
Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes. PMID:30053068
A New Bioactive Compound From the Marine Sponge-Derived Streptomyces sp. SBT348 Inhibits Staphylococcal Growth and Biofilm Formation. PMID:30050506
Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells. PMID:30050079
Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis. PMID:30048641
Automatic extraction of gene-disease associations from literature using joint ensemble learning. PMID:30048465
Analysis of public RNA-sequencing data reveals biological consequences of genetic heterogeneity in cell line populations. PMID:30046134
Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks. PMID:30046115
Network Rewiring in Cancer: Applications to Melanoma Cell Lines and the Cancer Genome Atlas Patients. PMID:30042785
Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data. PMID:30041657
Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity. PMID:30039798
Construction of Discrete Model of Human Pluripotency in Predicting Lineage-Specific Outcomes and Targeted Knockdowns of Essential Genes. PMID:30038409
The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization. PMID:30037897
Investigation of epigenetic regulatory networks associated with autism spectrum disorder (ASD) by integrated global LINE-1 methylation and gene expression profiling analyses. PMID:30036398
Using Transcriptomes as Mutant Phenotypes Reveals Functional Regions of a Mediator Subunit in Caenorhabditis elegans. PMID:30030292
Dual RNA-Seq Analysis of Trichophyton rubrum and HaCat Keratinocyte Co-Culture Highlights Important Genes for Fungal-Host Interaction. PMID:30029541
The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma. PMID:30026510
Transcriptional Profiling of Immune-Related Genes in Leishmania infantum-Infected Mice: Identification of Potential Biomarkers of Infection and Progression of Disease. PMID:30013952
Altered Gene Expression in Prefrontal Cortex of a Fabry Disease Mouse Model. PMID:30013462
Dynamics of the Pollen Sequestrome Defined by Subcellular Coupled Omics. PMID:30007911
Integrated Analysis of Quantitative Proteome and Transcriptional Profiles Reveals the Dynamic Function of Maternally Expressed Proteins After Parthenogenetic Activation of Buffalo Oocyte. PMID:30002204
Gene expression profiles in neurological tissues during West Nile virus infection: a critical meta-analysis. PMID:30001706
Alternative empirical Bayes models for adjusting for batch effects in genomic studies. PMID:30001694
Transcriptional Alterations in the Trigeminal Ganglia, Nucleus and Peripheral Blood Mononuclear Cells in a Rat Orofacial Pain Model. PMID:29997476
The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers. PMID:29996881
Novel dual regulators of Pseudomonas aeruginosa essential for productive biofilms and virulence. PMID:29995308
Translational Bioinformatics for Cholangiocarcinoma: Opportunities and Challenges. PMID:29989102
Expression of Adhesive Pili and the Collagen-Binding Adhesin Ace Is Activated by ArgR Family Transcription Factors in Enterococcus faecalis. PMID:29986940
MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells. PMID:29986211
Germline DNA replication timing shapes mammalian genome composition. PMID:29986092
Predicting Risk of Postoperative Disease Recurrence in Crohn's Disease: Patients With Indolent Crohn's Disease Have Distinct Whole Transcriptome Profiles at the Time of First Surgery. PMID:29982468
Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy. PMID:29979676
Arsenic Reduces Gene Expression Response to Changing Salinity in Killifish. PMID:29979584
Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver. PMID:29973619
Maternal obesity has sex-dependent effects on insulin, glucose and lipid metabolism and the liver transcriptome in young adult rat offspring. PMID:29972240
Pirfenidone decreases mesothelioma cell proliferation and migration via inhibition of ERK and AKT and regulates mesothelioma tumor microenvironment in vivo. PMID:29968778
Inhibition of integrin αVβ6 changes fibril thickness of stromal collagen in experimental carcinomas. PMID:29966518
Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species. PMID:29958539
Histology and Transcriptome Profiles of the Mammary Gland across Critical Windows of Development in Sprague Dawley Rats. PMID:29956080
Metabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor. PMID:29950287
LONGO: an R package for interactive gene length dependent analysis for neuronal identity. PMID:29950021
GSEA-InContext: identifying novel and common patterns in expression experiments. PMID:29950010
SigMat: a classification scheme for gene signature matching. PMID:29950002
Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population. PMID:29945935
aaquetzalli is required for epithelial cell polarity and neural tissue formation in Drosophila. PMID:29942698
Stable STIM1 Knockdown in Self-Renewing Human Neural Precursors Promotes Premature Neural Differentiation. PMID:29942250
Temporal transcriptomic analysis of metabolic genes in maternal organs and placenta during murine pregnancy. PMID:29939228
Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent. PMID:29938200
Regulatory RNA binding proteins contribute to the transcriptome-wide splicing alterations in human cellular senescence. PMID:29936497
Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression. PMID:29927984
Co-Expression Network Analysis of AMPK and Autophagy Gene Products during Adipocyte Differentiation. PMID:29921805
Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. PMID:29921600
Developments in toxicogenomics: understanding and predicting compound-induced toxicity from gene expression data. PMID:29917034
Presymptomatic change in microRNAs modulates Tau pathology. PMID:29915328
GeNets: a unified web platform for network-based genomic analyses. PMID:29915188
SAMHD1 modulates in vitro proliferation of acute myeloid leukemia-derived THP-1 cells through the PI3K-Akt-p27 axis. PMID:29911928
Damage-associated molecular pattern recognition is required for induction of retinal neuroprotective pathways in a sex-dependent manner. PMID:29904087
MicroRNA-30 modulates metabolic inflammation by regulating Notch signaling in adipose tissue macrophages. PMID:29899524
A data mining paradigm for identifying key factors in biological processes using gene expression data. PMID:29899432
Dietary Intake of Curcumin Improves eIF2 Signaling and Reduces Lipid Levels in the White Adipose Tissue of Obese Mice. PMID:29899429
Transcriptomic immune profiling of ovarian cancers in paraneoplastic cerebellar degeneration associated with anti-Yo antibodies. PMID:29899393
KLRD1-expressing natural killer cells predict influenza susceptibility. PMID:29898768
The Probiotic Escherichia coli Strain Nissle 1917 Combats Lambdoid Bacteriophages stx and λ. PMID:29896160
SSMART: sequence-structure motif identification for RNA-binding proteins. PMID:29893814
Transcriptome analysis highlights nuclear control of chloroplast development in the shoot apex. PMID:29892011
Lmo2 expression defines tumor cell identity during T-cell leukemogenesis. PMID:29880602
The Kinase Complex mTOR Complex 2 Promotes the Follicular Migration and Functional Maturation of Differentiated Follicular Helper CD4+ T Cells During Viral Infection. PMID:29875775
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP. PMID:29868516
Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm Birth. PMID:29867970
SV-BR-1-GM, a Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses an Immune Signature and Directly Activates CD4+ T Lymphocytes. PMID:29867922
Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex. PMID:29859039
Targeted Transcriptional Profiling of Kidney Transplant Biopsies. PMID:29854981
Disease-Specific Integration of Omics Data to Guide Functional Validation of Genetic Associations. PMID:29854229
Fast and Accurate Metadata Authoring Using Ontology-Based Recommendations. PMID:29854196
A big data pipeline: Identifying dynamic gene regulatory networks from time-course Gene Expression Omnibus data with applications to influenza infection. PMID:29846143
Identification of candidate biomarkers and pathways associated with SCLC by bioinformatics analysis. PMID:29845250
Identification and analysis of ribosome-associated lncRNAs using ribosome profiling data. PMID:29843593
Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice. PMID:29809134
Supplementation of fructooligosaccharides to suckling piglets affects intestinal microbiota colonization and immune development. PMID:29800418
Identification of genes involved in metabolism and signalling of abscisic acid and gibberellins during Epimedium pseudowushanense B.L.Guo seed morphophysiological dormancy. PMID:29796945
A 2-transcript host cell signature distinguishes viral from bacterial diarrhea and it is influenced by the severity of symptoms. PMID:29795312
BRG1 governs glucocorticoid receptor interactions with chromatin and pioneer factors across the genome. PMID:29792595
Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. PMID:29791859
Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models. PMID:29789628
CellAtlasSearch: a scalable search engine for single cells. PMID:29788498
Sphingosine-1-Phosphate Signaling and Metabolism Gene Signature in Pediatric Inflammatory Bowel Disease: A Matched-case Control Pilot Study. PMID:29788359
High-fructose diet during adolescent development increases neuroinflammation and depressive-like behavior without exacerbating outcomes after stroke. PMID:29787857
Reversal of siRNA-mediated gene silencing in vivo. PMID:29786096
Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis. PMID:29784888
Biomarker microRNAs for prostate cancer metastasis: screened with a network vulnerability analysis model. PMID:29784056
Human plasma and serum extracellular small RNA reference profiles and their clinical utility. PMID:29777089
Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors. PMID:29774130
Methylation guide RNA evolution in archaea: structure, function and genomic organization of 110 C/D box sRNA families across six Pyrobaculum species. PMID:29771354
Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PMID:29763473
Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons. PMID:29755449
Decoding Common Features of Neurodegenerative Disorders: From Differentially Expressed Genes to Pathways. PMID:29755292
Multiclass classification for skin cancer profiling based on the integration of heterogeneous gene expression series. PMID:29750795
Identification of novel drug targets for diamond-blackfan anemia based on RPS19 gene mutation using protein-protein interaction network. PMID:29745857
Automated transition analysis of activated gene regulation during diauxic nutrient shift in Escherichia coli and adipocyte differentiation in mouse cells. PMID:29745848
An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer. PMID:29744254
UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response. PMID:29743725
Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia. PMID:29743478
Paternal developmental toxicant exposure is associated with epigenetic modulation of sperm and placental Pgr and Igf2 in a mouse model. PMID:29741588
MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer. PMID:29739788
Time-evolving genetic networks reveal a NAC troika that negatively regulates leaf senescence in Arabidopsis. PMID:29735710
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia. PMID:29731978
Human serum and platelet lysate are appropriate xeno-free alternatives for clinical-grade production of human MuStem cell batches. PMID:29720259
Identification and characterization of the Komagataella phaffii mating pheromone genes. PMID:29718186
Low-level laser irradiation induces a transcriptional myotube-like profile in C2C12 myoblasts. PMID:29717386
Structural and functional dissection of differentially expressed tomato WRKY transcripts in host defense response against the vascular wilt pathogen (Fusarium oxysporum f. sp. lycopersici). PMID:29709017
DANUBE: Data-driven meta-ANalysis using UnBiased Empirical distributions-applied to biological pathway analysis. PMID:29706661
New perspectives: systems medicine in cardiovascular disease. PMID:29699591
IncGraph: Incremental graphlet counting for topology optimisation. PMID:29698494
Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma. PMID:29693014
CellExpress: a comprehensive microarray-based cancer cell line and clinical sample gene expression analysis online system. PMID:29688349
Community-driven roadmap for integrated disease maps. PMID:29688273
Genome-wide analyses of late pollen-preferred genes conserved in various rice cultivars and functional identification of a gene involved in the key processes of late pollen development. PMID:29687350
Integrated genome-wide Alu methylation and transcriptome profiling analyses reveal novel epigenetic regulatory networks associated with autism spectrum disorder. PMID:29686828
Domains within RbpA Serve Specific Functional Roles That Regulate the Expression of Distinct Mycobacterial Gene Subsets. PMID:29686140
The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism. PMID:29686054
Mapping Interaction Sites on Human Chemokine Receptors by Deep Mutational Scanning. PMID:29678950
Specific breast cancer prognosis-subtype distinctions based on DNA methylation patterns. PMID:29675884
Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition. PMID:29674686
BBS9 gene in nonsyndromic craniosynostosis: Role of the primary cilium in the aberrant ossification of the suture osteogenic niche. PMID:29674126
ANLN functions as a key candidate gene in cervical cancer as determined by integrated bioinformatic analysis. PMID:29670400
Global H3.3 dynamic deposition defines its bimodal role in cell fate transition. PMID:29670118
ASB1 differential methylation in ischaemic cardiomyopathy: relationship with left ventricular performance in end-stage heart failure patients. PMID:29667349
Arsenic trioxide-mediated suppression of miR-182-5p is associated with potent anti-oxidant effects through up-regulation of SESN2. PMID:29662624
Activation of TRPV3 by Wood Smoke Particles and Roles in Pneumotoxicity. PMID:29658714
Sponge Long Non-Coding RNAs Are Expressed in Specific Cell Types and Conserved Networks. PMID:29657303
FAR2 is associated with kidney disease in mice and humans. PMID:29652635
Bioinformatic analysis reveals the key pathways and genes in early-onset breast cancer. PMID:29644522
Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT. PMID:29643855
A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria. PMID:29642892
Condition-Specific Modeling of Biophysical Parameters Advances Inference of Regulatory Networks. PMID:29641998
A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors. PMID:29638227
Massive mining of publicly available RNA-seq data from human and mouse. PMID:29636450
Dietary and Endocrine Regulation of Endogenous Hydrogen Sulfide Production: Implications for Longevity. PMID:29634343
Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner. PMID:29632368
Identification of Prognostic Biomarkers by Combined mRNA and miRNA Expression Microarray Analysis in Pancreatic Cancer. PMID:29631214
TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma. PMID:29620272
Identification of key genes in non‑alcoholic fatty liver disease progression based on bioinformatics analysis. PMID:29620197
Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. PMID:29618843
Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls. PMID:29618798
Global dynamics of stage-specific transcription factor binding during thymocyte development. PMID:29618724
Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. PMID:29617658
Radiation-Induced Gene Expression Changes in High and Low Grade Breast Cancer Cell Types. PMID:29617354
Expression of the microRNA-143/145 cluster is decreased in hepatitis B virus-associated hepatocellular carcinoma and may serve as a biomarker for tumorigenesis in patients with chronic hepatitis B. PMID:29616093
Adjusting for Batch Effects in DNA Methylation Microarray Data, a Lesson Learned. PMID:29616078
Pairwise gene GO-based measures for biclustering of high-dimensional expression data. PMID:29610579
Divergence in DNA Specificity among Paralogous Transcription Factors Contributes to Their Differential In Vivo Binding. PMID:29605182
Identification of the key transcription factors in esophageal squamous cell carcinoma. PMID:29600044
Neurogenomic Profiling Reveals Distinct Gene Expression Profiles Between Brain Parts That Are Consistent in Ophthalmotilapia Cichlids. PMID:29593484
GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing. PMID:29590075
Heuristic algorithms for feature selection under Bayesian models with block-diagonal covariance structure. PMID:29589558
Methylation-to-Expression Feature Models of Breast Cancer Accurately Predict Overall Survival, Distant-Recurrence Free Survival, and Pathologic Complete Response in Multiple Cohorts. PMID:29581450
Comprehensive analysis of Helicobacter pylori infection-associated diseases based on miRNA-mRNA interaction network. PMID:29579224
Burden-driven feedback control of gene expression. PMID:29578536
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation. PMID:29576451
Induction of Genes Encoding Plant Cell Wall-Degrading Carbohydrate-Active Enzymes by Lignocellulose-Derived Monosaccharides and Cellobiose in the White-Rot Fungus Dichomitus squalens. PMID:29572208
Lysosomal acid lipase promotes cholesterol ester metabolism and drives clear cell renal cell carcinoma progression. PMID:29569766
Blocking hexose entry into glycolysis activates alternative metabolic conversion of these sugars and upregulates pentose metabolism in Aspergillus nidulans. PMID:29566661
No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation. PMID:29564022
A switch in transcription and cell fate governs the onset of an epigenetically-deregulated tumor in Drosophila. PMID:29560857
Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor. PMID:29559630
New drug candidates for treatment of atypical meningiomas: An integrated approach using gene expression signatures for drug repurposing. PMID:29558515
Characterization of human dental pulp cells grown in chemically defined serum-free medium. PMID:29556382
Lowered dietary phosphorus affects intestinal and renal gene expression to maintain mineral homeostasis with immunomodulatory implications in weaned piglets. PMID:29554878
Could ALDH2*2 be the reason for low incidence and mortality of ovarian cancer for East Asia women? PMID:29552329
Epigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness. PMID:29549885
Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells. PMID:29543748
A novel computational approach for drug repurposing using systems biology. PMID:29534151
A regulatory RNA is involved in RNA duplex formation and biofilm regulation in Sulfolobus acidocaldarius. PMID:29529252
p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. PMID:29523821
EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer. PMID:29518696
TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury. PMID:29517978
Extracellular vesicle RNAs reflect placenta dysfunction and are a biomarker source for preterm labour. PMID:29516617
Genome-wide transcriptome analysis identifies alternative splicing regulatory network and key splicing factors in mouse and human psoriasis. PMID:29515135
Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism. PMID:29514978
The mRNA, miRNA and lncRNA networks in hepatocellular carcinoma: An integrative transcriptomic analysis from Gene Expression Omnibus. PMID:29512731
A standardized fold change method for microarray differential expression analysis used to reveal genes involved in acute rejection in murine allograft models. PMID:29511625
Protein interaction mapping interpretation of none alcoholic fatty liver disease model of rats after fat diet feeding. PMID:29511485
Association of miR-548c-5p, miR-7-5p, miR-210-3p, miR-128-3p with recurrence in systemically untreated breast cancer. PMID:29507672
Zc3h10 is a novel mitochondrial regulator. PMID:29507079
CRISPR RNA-Dependent Binding and Cleavage of Endogenous RNAs by the Campylobacter jejuni Cas9. PMID:29499139
Computational de novo discovery of distinguishing genes for biological processes and cell types in complex tissues. PMID:29494600
A minimal RNA ligand for potent RIG-I activation in living mice. PMID:29492454
Loss of Pax5 Exploits Sca1-BCR-ABLp190 Susceptibility to Confer the Metabolic Shift Essential for pB-ALL. PMID:29490943
Modulation of the peripheral blood transcriptome by the ingestion of probiotic yoghurt and acidified milk in healthy, young men. PMID:29489876
Functional Genomics and Phylogenetic Evidence Suggest Genus-Wide Cobalamin Production by the Globally Distributed Marine Nitrogen Fixer Trichodesmium. PMID:29487583
Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae. PMID:29487291
Datasets2Tools, repository and search engine for bioinformatics datasets, tools and canned analyses. PMID:29485625
Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury. PMID:29482641
Novel Dual-Action Targeted Nanomedicine in Mice With Metastatic Thyroid Cancer and Pancreatic Neuroendocrine Tumors. PMID:29481652
A novel joint analysis framework improves identification of differentially expressed genes in cross disease transcriptomic analysis. PMID:29467826
Distinguishing Human Peripheral Blood NK Cells from CD56dimCD16dimCD69+CD103+ Resident Nasal Mucosal Lavage Fluid Cells. PMID:29467466
Epigenome comparisons reveal linkage between gene expression and postnatal remodeling of chromatin domain topology. PMID:29466355
Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer. PMID:29464091
Longitudinal analysis strategies for modelling epigenetic trajectories. PMID:29462323
A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics. PMID:29462216
Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity. PMID:29459660
CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses. PMID:29458351
Mixed-species RNAseq analysis of human lymphoma cells adhering to mouse stromal cells identifies a core gene set that is also differentially expressed in the lymph node microenvironment of mantle cell lymphoma and chronic lymphocytic leukemia patients. PMID:29449436
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids. PMID:29440725
Small RNAs of Haloferax mediterranei: Identification and Potential Involvement in Nitrogen Metabolism. PMID:29439418
hMENA is a key regulator in endothelin-1/β-arrestin1-induced invadopodial function and metastatic process. PMID:29439204
IKKα is required in the intestinal epithelial cells for tumour stemness. PMID:29438366
Mutational Pleiotropy and the Strength of Stabilizing Selection Within and Between Functional Modules of Gene Expression. PMID:29437825
Combining laser-assisted microdissection (LAM) and RNA-seq allows to perform a comprehensive transcriptomic analysis of epidermal cells of Arabidopsis embryo. PMID:29434651
Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development. PMID:29423101
Signatures of Altered Gene Expression in Dorsal Root Ganglia of a Fabry Disease Mouse Model. PMID:29422837
MELK expression correlates with tumor mitotic activity but is not required for cancer growth. PMID:29417930
Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA. PMID:29416646
Transcriptome-wide survey of gene expression changes and alternative splicing in Trichophyton rubrum in response to undecanoic acid. PMID:29410524
PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse. PMID:29409495
Single-cell profiling of peanut-responsive T cells in patients with peanut allergy reveals heterogeneous effector TH2 subsets. PMID:29408715
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance. PMID:29402381
A practical solution for preserving single cells for RNA sequencing. PMID:29391536
Modified Cross-Linking, Ligation, and Sequencing of Hybrids (qCLASH) Identifies Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Targets in Endothelial Cells. PMID:29386283
Germline contamination and leakage in whole genome somatic single nucleotide variant detection. PMID:29385983
Vital ex vivo tissue labeling and pathology-guided micropunching to characterize cellular heterogeneity in the tissue microenvironment. PMID:29384072
Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo. PMID:29383126
Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance. PMID:29379303
A Two-Stage Whole-Genome Gene Expression Association Study of Young-Onset Hypertension in Han Chinese Population of Taiwan. PMID:29379041
Additive Effects of Quorum Sensing Anti-Activators on Pseudomonas aeruginosa Virulence Traits and Transcriptome. PMID:29375519
Biofilm formation and transcriptome analysis of Streptococcus gallolyticus subsp. gallolyticus in response to lysozyme. PMID:29373594
Cell-surface marker discovery for lung cancer. PMID:29371917
The Biotrophic Development of Ustilago maydis Studied by RNA-Seq Analysis. PMID:29371439
Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development. PMID:29361559
The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer's Disease. PMID:29359159
Gene annotation bias impedes biomedical research. PMID:29358745
The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding. PMID:29358041
DataMed - an open source discovery index for finding biomedical datasets. PMID:29346583
The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. PMID:29343498
Identification of bladder cancer prognostic biomarkers using an ageing gene-related competitive endogenous RNA network. PMID:29340088
A novel messenger RNA signature as a prognostic biomarker for predicting relapse in pancreatic ductal adenocarcinoma. PMID:29340021
Application of Weighted Gene Co-expression Network Analysis for Data from Paired Design. PMID:29330528
Base-Resolution Analysis of DNA Methylation Patterns Downstream of Dnmt3a in Mouse Naïve B Cells. PMID:29326230
Omics Assisted N-terminal Proteoform and Protein Expression Profiling On Methionine Aminopeptidase 1 (MetAP1) Deletion. PMID:29317475
Toxoplasma gondii Infection Is Associated with Mitochondrial Dysfunction in-Vitro. PMID:29312892
Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes. PMID:29311748
Transcriptomic Analysis Reveals Novel Mechanisms Mediating Islet Dysfunction in the Intrauterine Growth-Restricted Rat. PMID:29309562
Boolean network modeling in systems pharmacology. PMID:29307099
POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain. PMID:29305536
A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects. PMID:29300724
ASXL1 and BIM germ line variants predict response and identify CML patients with the greatest risk of imatinib failure. PMID:29296778
Clonal evolution underlying leukemia progression and Richter transformation in patients with ibrutinib-relapsed CLL. PMID:29296715
Identification and validation long non-coding RNAs of oral squamous cell carcinoma by bioinformatics method. PMID:29296179
Impact of Consuming Extra-Virgin Olive Oil or Nuts within a Mediterranean Diet on DNA Methylation in Peripheral White Blood Cells within the PREDIMED-Navarra Randomized Controlled Trial: A Role for Dietary Lipids. PMID:29295516
Mutations in the DNA methylation pathway and number of driver mutations predict response to azacitidine in myelodysplastic syndromes. PMID:29291002
Identification and Functional Validation of a Biomarker for the Diagnosis of Miltefosine Relapse during Visceral Leishmaniasis. PMID:29280431
Cancer transcriptome profiling at the juncture of clinical translation. PMID:29279605
Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response. PMID:29276753
PITX1 promotes chondrogenesis and myogenesis in mouse hindlimbs through conserved regulatory targets. PMID:29273440
Transcriptional Response to Lactic Acid Stress in the Hybrid Yeast Zygosaccharomyces parabailii. PMID:29269498
Super-delta: a new differential gene expression analysis procedure with robust data normalization. PMID:29268715
Circular RNA expression is abundant and correlated to aggressiveness in early-stage bladder cancer. PMID:29263845
Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen. PMID:29263829
Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines. PMID:29262566
Clearance of a persistent picornavirus infection is associated with enhanced pro-apoptotic and cellular immune responses. PMID:29259271
Bioinformatics analysis of differentially expressed gene profiles associated with systemic lupus erythematosus. PMID:29257335
High expression of FLT3 is a risk factor in leukemia. PMID:29257272
Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes. PMID:29255003
FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors. PMID:29249665
Potential Diagnostic Power of Blood Circular RNA Expression in Active Pulmonary Tuberculosis. PMID:29248507
Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels. PMID:29234000
Ensemble Modeling Approach Targeting Heterogeneous RNA-Seq data: Application to Melanoma Pseudogenes. PMID:29229974
Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo. PMID:29229863
SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer. PMID:29229751
Global gene expression in two potato cultivars in response to 'Candidatus Liberibacter solanacearum' infection. PMID:29228896
In-Cardiome: integrated knowledgebase for coronary artery disease enabling translational research. PMID:29220465
SFMetaDB: a comprehensive annotation of mouse RNA splicing factor RNA-Seq datasets. PMID:29220461
Annotating gene sets by mining large literature collections with protein networks. PMID:29218918
Advances in Text Mining and Visualization for Precision Medicine. PMID:29218914
Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads. PMID:29216900
Systematic integrative analysis of gene expression identifies HNF4A as the central gene in pathogenesis of non-alcoholic steatohepatitis. PMID:29216278
Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach. PMID:29215067
Platelet-rich plasma inhibits RANKL-induced osteoclast differentiation through activation of Wnt pathway during bone remodeling. PMID:29207140
Slam protein dictates subcellular localization and translation of its own mRNA. PMID:29206227
Cross-Laboratory Analysis of Brain Cell Type Transcriptomes with Applications to Interpretation of Bulk Tissue Data. PMID:29204516
Mediator Complex Subunits MED2, MED5, MED16, and MED23 Genetically Interact in the Regulation of Phenylpropanoid Biosynthesis. PMID:29203634
Lymph Node Metastases in Colon Cancer Are Polyclonal. PMID:29203589
Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes. PMID:29198749
Protection of macrophages from intracellular pathogens by miR-182-5p mimic-a gene expression meta-analysis approach. PMID:29197182
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. PMID:29195078
Transcription Factor-Mediated Control of Anthocyanin Biosynthesis in Vegetative Tissues. PMID:29192027
Genetic variation at the microRNA binding site of CAV1 gene is associated with lung cancer susceptibility. PMID:29190968
The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells. PMID:29190885
Conditional Loss of Hoxa5 Function Early after Birth Impacts on Expression of Genes with Synaptic Function. PMID:29187810
Integrative Bioinformatic Analysis of Transcriptomic Data Identifies Conserved Molecular Pathways Underlying Ionizing Radiation-Induced Bystander Effects (RIBE). PMID:29186820
Translational bioinformatics in mental health: open access data sources and computational biomarker discovery. PMID:29186302
RNA sequencing reveals candidate genes and polymorphisms related to sperm DNA integrity in testis tissue from boars. PMID:29183316
Selection of internal references for qRT-PCR assays of human hepatocellular carcinoma cell lines. PMID:29180379
Nutrient-Colimited Trichodesmium as a Nitrogen Source or Sink in a Future Ocean. PMID:29180365
ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis. PMID:29178829
A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes. PMID:29173897
The histone code reader Spin1 controls skeletal muscle development. PMID:29168801
Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria. PMID:29165665
Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells. PMID:29163771
NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation. PMID:29161413
Regulation of Sucrose Transporters and Phloem Loading in Response to Environmental Cues. PMID:29158330
Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy. PMID:29157747
Identification of potential tissue-specific cancer biomarkers and development of cancer versus normal genomic classifiers. PMID:29156751
Comprehensive functional enrichment analysis of male infertility. PMID:29150651
Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness. PMID:29149419
A transcriptomic insight into the impacts of mast cells in lung, breast, and colon cancers. PMID:29147625
Hypomethylation of HOXA4 promoter is common in Silver-Russell syndrome and growth restriction and associates with stature in healthy children. PMID:29146936
Global analysis of gene expression mediated by OX1 orexin receptor signaling in a hypothalamic cell line. PMID:29145494
Innate Cell-Mediated Cytotoxic Activity of European Sea Bass Leucocytes Against Nodavirus-Infected Cells: A Functional and RNA-seq Study. PMID:29133947
A Novel Mechanism of Inactivating Antibacterial Nitro Compounds in the Human Pathogen Staphylococcus aureus by Overexpression of a NADH-Dependent Flavin Nitroreductase. PMID:29133557
Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development. PMID:29133375
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data. PMID:29130882
Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10 and Wnt5a. PMID:29126155
Missing data and technical variability in single-cell RNA-sequencing experiments. PMID:29121214
ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT. PMID:29118335
Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers. PMID:29118262
General response of Salmonella enterica serovar Typhimurium to desiccation: A new role for the virulence factors sopD and sseD in survival. PMID:29117268
Crosstalk between Receptor and Non-receptor Mediated Chemical Modes of Action in Rat Livers Converges through a Dysregulated Gene Expression Network at Tumor Suppressor Tp53. PMID:29114260
Restricted Presence of POU6F2 in Human Corneal Endothelial Cells Uncovered by Extension of the Promoter-level Expression Atlas. PMID:29113774
In vivo functional analysis of L-rhamnose metabolic pathway in Aspergillus niger: a tool to identify the potential inducer of RhaR. PMID:29110642
Deep Learning Accurately Predicts Estrogen Receptor Status in Breast Cancer Metabolomics Data. PMID:29110491
Transcriptional responses of wheat and the cereal cyst nematode Heterodera avenae during their early contact stage. PMID:29101332
Cellular, ultrastructural and molecular analyses of epidermal cell development in the planarian Schmidtea mediterranea. PMID:29100657
Gene expression information improves reliability of receptor status in breast cancer patients. PMID:29100391
Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles. PMID:29099860
A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation. PMID:29093060
GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells. PMID:29092903
Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice. PMID:29088242
The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. PMID:29087293
APC downregulated 1 inhibits breast cancer cell invasion by inhibiting the canonical WNT signaling pathway. PMID:29085490
Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics. PMID:29085363
Glycosylation-related gene expression in HT29-MTX-E12 cells upon infection by Helicobacter pylori. PMID:29085225
In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer. PMID:29084986
Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid Growth Factor Receptor (OGFr). PMID:29079719
Comparative genomics of geographically distant Fusarium fujikuroi isolates revealed two distinct pathotypes correlating with secondary metabolite profiles. PMID:29073267
Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder. PMID:29066808
Gene isoforms as expression-based biomarkers predictive of drug response in vitro. PMID:29066719
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein. PMID:29061731
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia. PMID:29059365
PpNAC1, a main regulator of phenylalanine biosynthesis and utilization in maritime pine. PMID:29055073
Genome-wide prediction of DNase I hypersensitivity using gene expression. PMID:29051481
A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates. PMID:29049289
miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis. PMID:29048402
Modulation of Global Transcriptional Regulatory Networks as a Strategy for Increasing Kanamycin Resistance of the Translational Elongation Factor-G Mutants in Escherichia coli. PMID:29046437
Roles of Female and Male Genotype in Post-Mating Responses in Drosophila melanogaster. PMID:29036644
ScanGEO: parallel mining of high-throughput gene expression data. PMID:29036513
Smooth quantile normalization. PMID:29036413
Hedgehog-mesenchyme gene signature identifies bi-modal prognosis in luminal and basal breast cancer sub-types. PMID:29034935
Designing Dietary Recommendations Using System Level Interactomics Analysis and Network-Based Inference. PMID:29033850
Single-cell RNA sequencing reveals developmental heterogeneity among early lymphoid progenitors. PMID:29030486
RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1. PMID:29030483
Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK. PMID:29024417
Differential gene expression in disease: a comparison between high-throughput studies and the literature. PMID:29020950
Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses. PMID:28993767
Effect of diabetes status and hyperglycemia on global DNA methylation and hydroxymethylation. PMID:28993426
SCENIC: single-cell regulatory network inference and clustering. PMID:28991892
Architectural alterations of the fission yeast genome during the cell cycle. PMID:28991264
Investigating the microRNA-mRNA regulatory network in acute myeloid leukemia. PMID:28989535
Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen. PMID:28987030
Impact of sequencing depth and read length on single cell RNA sequencing data of T cells. PMID:28986563
RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking. PMID:28985737
A link prediction approach to cancer drug sensitivity prediction. PMID:28984192
Usefulness of Transcriptional Blood Biomarkers as a Non-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response in Ulcerative Colitis. PMID:28981629
IMOTA: an interactive multi-omics tissue atlas for the analysis of human miRNA-target interactions. PMID:28977416
Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa. PMID:28974743
Meta-analysis of transcriptomic datasets identifies genes enriched in the mammalian circadian pacemaker. PMID:28973476
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis. PMID:28968850
A framework for estimating and testing qualitative interactions with applications to predictive biomarkers. PMID:28968765
Identification of candidate genes associated with triple negative breast cancer. PMID:28966727
Transcriptomic responses of the endangered freshwater mussel Margaritifera margaritifera to trace metal contamination in the Dronne River, France. PMID:28963680
Statistically controlled identification of differentially expressed genes in one-to-one cell line comparisons of the CMAP database for drug repositioning. PMID:28962576
Inference and interrogation of a coregulatory network in the context of lipid accumulation in Yarrowia lipolytica. PMID:28955503
Stable Gene Regulatory Network Modeling From Steady-State Data. PMID:28952574
Filamentation Involves Two Overlapping, but Distinct, Programs of Filamentation in the Pathogenic Fungus Candida albicans. PMID:28951491
Pathway and network-based analysis of genome-wide association studies and RT-PCR validation in polycystic ovary syndrome. PMID:28949383
Peroxisome proliferator-activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut. PMID:28947679
Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor. PMID:28947539
Integrated metabolic models for xenobiotic induced mitochondrial toxicity in skeletal muscle. PMID:28942197
Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics. PMID:28941356
Differential expression and co-expression gene networks reveal candidate biomarkers of boar taint in non-castrated pigs. PMID:28939879
The Transcriptome of Estrogen-Independent Mammary Growth in Female Mice Reveals That Not All Mammary Glands Are Created Equally. PMID:28938404
Systematic integration of biomedical knowledge prioritizes drugs for repurposing. PMID:28936969
Light and Plastid Signals Regulate Different Sets of Genes in the Albino Mutant Pap7-1. PMID:28935841
A comprehensive, cell specific microRNA catalogue of human peripheral blood. PMID:28934507
Intercalated disc in failing hearts from patients with dilated cardiomyopathy: Its role in the depressed left ventricular function. PMID:28934278
Comparative transcriptomics of female and male gametocytes in Plasmodium berghei and the evolution of sex in alveolates. PMID:28923023
Complete Circular Genome Sequence and Temperature Independent Adaptation to Anaerobiosis of Listeria weihenstephanensis DSM 24698. PMID:28919887
An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides. PMID:28916805
Data exploration, quality control and statistical analysis of ChIP-exo/nexus experiments. PMID:28911122
Screening and identification of key biomarkers in hepatocellular carcinoma: Evidence from bioinformatic analysis. PMID:28901457
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation. PMID:28899353
Determining the optimal number of independent components for reproducible transcriptomic data analysis. PMID:28893186
Mining the Volatilomes of Plant-Associated Microbiota for New Biocontrol Solutions. PMID:28890716
MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells. PMID:28887500
Integrated expression profiles analysis reveals novel predictive biomarker in pancreatic ductal adenocarcinoma. PMID:28881752
An in-silico approach to predict and exploit synthetic lethality in cancer metabolism. PMID:28878380
FunctionAnnotator, a versatile and efficient web tool for non-model organism annotation. PMID:28874813
HT-SuperSAGE of the gut tissue of a Vip3Aa-resistant Heliothis virescens (Lepidoptera: Noctuidae) strain provides insights into the basis of resistance. PMID:28872766
A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research. PMID:28872130
Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma. PMID:28859336
Retinol saturase coordinates liver metabolism by regulating ChREBP activity. PMID:28855500
Ribosome signatures aid bacterial translation initiation site identification. PMID:28854918
Study on molecular mechanism of ANOS1 promoting development of colorectal cancer. PMID:28854193
Novel evidence for complement system activation in chick myopia and hyperopia models: a meta-analysis of transcriptome datasets. PMID:28852117
Genome-wide expression and response to exposure-based psychological therapy for anxiety disorders. PMID:28850109
Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function. PMID:28848560
Expression and Regulatory Network Analysis of miR-140-3p, a New Potential Serum Biomarker for Autism Spectrum Disorder. PMID:28848387
An improved analysis methodology for translational profiling by microarray. PMID:28842509
Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient. PMID:28841418
Microbial regulation of microRNA expression in the amygdala and prefrontal cortex. PMID:28838324
Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development. PMID:28831049
Measuring mRNA Levels Over Time During the Yeast S. cerevisiae Hypoxic Response. PMID:28829420
DELLA genes restrict inflorescence meristem function independently of plant height. PMID:28827519
A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. PMID:28826505
Ribonucleotide Reductases from Bifidobacteria Contain Multiple Conserved Indels Distinguishing Them from All Other Organisms: In Silico Analysis of the Possible Role of a 43 aa Bifidobacteria-Specific Insert in the Class III RNR Homolog. PMID:28824557
Molecular bases for differential aging programs between flag and second leaves during grain-filling in rice. PMID:28821707
Sources to variability in circulating human miRNA signatures. PMID:28820329
Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons. PMID:28818525
Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa. PMID:28816603
Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies. PMID:28813678
Totipotency segregates between the sister blastomeres of two-cell stage mouse embryos. PMID:28811525
Pro- and anti-inflammatory responses of peripheral blood mononuclear cells induced by Staphylococcus aureus and Pseudomonas aeruginosa phages. PMID:28808331
Critical role for arginase 2 in obesity-associated pancreatic cancer. PMID:28808255
DNA Microarray Analysis of Estrogen Responsive Genes in Ishikawa Cells by Glabridin. PMID:28804245
Identification and characterization of a long non-coding RNA up-regulated during HIV-1 infection. PMID:28803142
Transcriptional Analysis of an Ammonium-Excreting Strain of Azotobacter vinelandii Deregulated for Nitrogen Fixation. PMID:28802272
Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing. PMID:28801656
EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork-Associated DNA Damage Repair. PMID:28801308
The nucleoid protein Dps binds genomic DNA of Escherichia coli in a non-random manner. PMID:28800583
Analytical Strategy to Prioritize Alzheimer's Disease Candidate Genes in Gene Regulatory Networks Using Public Expression Data. PMID:28800327
MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing. PMID:28798331
Identification and characterization of a new source of adult human neural progenitors. PMID:28796246
Host plant driven transcriptome plasticity in the salivary glands of the cabbage looper (Trichoplusia ni). PMID:28792546
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. PMID:28787124
Bioinformatics resources for deciphering the biogenesis and action pathways of plant small RNAs. PMID:28786034
Early involvement of cellular stress and inflammatory signals in the pathogenesis of tubulointerstitial kidney disease due to UMOD mutations. PMID:28785050
Cutting Edge: IL-2-Induced Expression of the Amino Acid Transporters SLC1A5 and CD98 Is a Prerequisite for NKG2D-Mediated Activation of Human NK Cells. PMID:28784848
Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally. PMID:28775827
Transcriptome and Metabolite Changes during Hydrogen Cyanamide-Induced Floral Bud Break in Sweet Cherry. PMID:28769948
Identification of key genes and pathways in Parkinson's disease through integrated analysis. PMID:28765971
Heme and nitric oxide binding by the transcriptional regulator DnrF from the marine bacterium Dinoroseobacter shibae increases napD promoter affinity. PMID:28765283
The metabolic regulator mTORC1 controls terminal myeloid differentiation. PMID:28763796
Integrated diagnostic network construction reveals a 4-gene panel and 5 cancer hallmarks driving breast cancer heterogeneity. PMID:28754978
The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling. PMID:28753614
Quantifying Gene Regulatory Relationships with Association Measures: A Comparative Study. PMID:28751908
miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma. PMID:28748534
Dissecting the contributions of time and microbe density to variation in immune gene expression. PMID:28747473
Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. PMID:28747341
Whole blood microRNA expression may not be useful for screening non-small cell lung cancer. PMID:28742859
The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages. PMID:28733487
ERK/MAPK Signaling Is Required for Pathway-Specific Striatal Motor Functions. PMID:28733355
Chloroplast Redox Status Modulates Genome-Wide Plant Responses during the Non-host Interaction of Tobacco with the Hemibiotrophic Bacterium Xanthomonas campestris pv. vesicatoria. PMID:28725231
Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity. PMID:28724976
Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells. PMID:28720766
CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets. PMID:28719601
Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition. PMID:28716088
Microarray analysis reveals key genes and pathways in Tetralogy of Fallot. PMID:28713939
Identification of Conserved and Novel MicroRNAs in Blueberry. PMID:28713413
Unsupervised Extraction of Stable Expression Signatures from Public Compendia with an Ensemble of Neural Networks. PMID:28711280
The CINSARC signature as a prognostic marker for clinical outcome in multiple neoplasms. PMID:28710396
Biological analysis of cancer specific microRNAs on function modeling in osteosarcoma. PMID:28710380
Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding. PMID:28708998
Rv3723/LucA coordinates fatty acid and cholesterol uptake in Mycobacterium tuberculosis. PMID:28708968
Lower Expression of SLC27A1 Enhances Intramuscular Fat Deposition in Chicken via Down-Regulated Fatty Acid Oxidation Mediated by CPT1A. PMID:28706492
Sexual dimorphisms of mRNA and miRNA in human/murine heart disease. PMID:28704447
GT-rich promoters can drive RNA pol II transcription and deposition of H2A.Z in African trypanosomes. PMID:28701485
Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. PMID:28698371
6S RNA in Rhodobacter sphaeroides: 6S RNA and pRNA transcript levels peak in late exponential phase and gene deletion causes a high salt stress phenotype. PMID:28692405
Reorganization of gene network for degradation of polycyclic aromatic hydrocarbons (PAHs) in Pseudomonas aeruginosa PAO1 under several conditions. PMID:28685384
Genome-wide mapping and analysis of aryl hydrocarbon receptor (AHR)- and aryl hydrocarbon receptor repressor (AHRR)-binding sites in human breast cancer cells. PMID:28681081
A Novel Unsupervised Algorithm for Biological Process-based Analysis on Cancer. PMID:28680165
Connected Gene Communities Underlie Transcriptional Changes in Cornelia de Lange Syndrome. PMID:28679547
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. PMID:28671686
CausalR: extracting mechanistic sense from genome scale data. PMID:28666369
dRNA-seq transcriptional profiling of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis NRRL18488 and general analysis of the transcriptome. PMID:28665778
KDM2B, an H3K36-specific demethylase, regulates apoptotic response of GBM cells to TRAIL. PMID:28661478
Functional Dissection of the Pol V Largest Subunit CTD in RNA-Directed DNA Methylation. PMID:28658626
Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature. PMID:28652588
Deciphering the role of the signal- and Sty1 kinase-dependent phosphorylation of the stress-responsive transcription factor Atf1 on gene activation. PMID:28652406
Protein homeostasis of a metastable subproteome associated with Alzheimer's disease. PMID:28652376
Identifying global expression patterns and key regulators in epithelial to mesenchymal transition through multi-study integration. PMID:28651527
Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation. PMID:28645917
A reference genome for Nicotiana tabacum enables map-based cloning of homeologous loci implicated in nitrogen utilization efficiency. PMID:28625162
Safe and Efficient Silencing with a Pol II, but Not a Pol lII, Promoter Expressing an Artificial miRNA Targeting Human Huntingtin. PMID:28624208
TGF-beta/atRA-induced Tregs express a selected set of microRNAs involved in the repression of transcripts related to Th17 differentiation. PMID:28620241
Insights from Global Analyses of Long Noncoding RNAs in Breast Cancer. PMID:28616363
Tricellulin is regulated via interleukin-13-receptor α2, affects macromolecule uptake, and is decreased in ulcerative colitis. PMID:28612843
Involvement of Chromatin Remodeling Genes and the Rho GTPases RhoB and CDC42 in Ovarian Clear Cell Carcinoma. PMID:28611940
Knowledge Discovery in Biological Databases for Revealing Candidate Genes Linked to Complex Phenotypes. PMID:28609292
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes. PMID:28607179
Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies. PMID:28603644
Hepatic expression profiles in retroviral infection: relevance to drug hypersensitivity risk. PMID:28603631
Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques. PMID:28599598
High-dose maternal folic acid supplementation before conception impairs reversal learning in offspring mice. PMID:28596566
Genetic Dissection of Nutrition-Induced Plasticity in Insulin/Insulin-Like Growth Factor Signaling and Median Life Span in a Drosophila Multiparent Population. PMID:28592498
High-resolution promoter map of human limbal epithelial cells cultured with keratinocyte growth factor and rho kinase inhibitor. PMID:28588247
NaviSE: superenhancer navigator integrating epigenomics signal algebra. PMID:28587674
Identification of the miRNA-target gene regulatory network in intracranial aneurysm based on microarray expression data. PMID:28587396
PA3225 Is a Transcriptional Repressor of Antibiotic Resistance Mechanisms in Pseudomonas aeruginosa. PMID:28584154
Newborn sex-specific transcriptome signatures and gestational exposure to fine particles: findings from the ENVIRONAGE birth cohort. PMID:28583124
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. PMID:28575377
Gene Expression (mRNA) Markers for Differentiating between Malignant and Benign Follicular Thyroid Tumours. PMID:28574441
MicroRNA profiling in the dentate gyrus in epileptic rats: The role of miR-187-3p. PMID:28562528
Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage compensation. PMID:28562241
Systems-based approach to examine the cytokine responses in primary mouse lung macrophages infected with low pathogenic avian Influenza virus circulating in South East Asia. PMID:28558796
Crops In Silico: Generating Virtual Crops Using an Integrative and Multi-scale Modeling Platform. PMID:28555150
Non-coding RNAs in the Ovarian Follicle. PMID:28553318
p16 Loss and E2F/cell cycle deregulation in infant posterior fossa ependymoma. PMID:28548702
Transcriptomics technologies. PMID:28545146
eIF1 modulates the recognition of suboptimal translation initiation sites and steers gene expression via uORFs. PMID:28541577
Identifying CpG sites with different differential methylation frequencies in colorectal cancer tissues based on individualized differential methylation analysis. PMID:28537885
RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. PMID:28537551
Induction of resident memory T cells enhances the efficacy of cancer vaccine. PMID:28537262
Genetic variants in the transcription regulatory region of MEGF10 are associated with autism in Chinese Han population. PMID:28536440
Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells. PMID:28533480
Abnormal expression of ATP1A1 and ATP1A2 in breast cancer. PMID:28529692
Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. PMID:28521739
Candidate miRNAs and pathogenesis investigation for hepatocellular carcinoma based on bioinformatics analysis. PMID:28521446
Essential Function of the Serine Hydroxymethyl Transferase (SHMT) Gene During Rapid Syncytial Cell Cycles in Drosophila. PMID:28515048
An RpoHI-Dependent Response Promotes Outgrowth after Extended Stationary Phase in the Alphaproteobacterium Rhodobacter sphaeroides. PMID:28507242
Toxic Electrophiles Induce Expression of the Multidrug Efflux Pump MexEF-OprN in Pseudomonas aeruginosa through a Novel Transcriptional Regulator, CmrA. PMID:28507116
Ranking metrics in gene set enrichment analysis: do they matter? PMID:28499413
Differences in Flower Transcriptome between Grapevine Clones Are Related to Their Cluster Compactness, Fruitfulness, and Berry Size. PMID:28496449
RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA+ and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells. PMID:28494942
Relationship between regulatory pattern of gene expression level and gene function. PMID:28494005
In vivo and in vitro ageing results in accumulation of de novo copy number variations in bulls. PMID:28487564
Study of Meta-analysis strategies for network inference using information-theoretic approaches. PMID:28484519
Integration of Immune Cell Populations, mRNA-Seq, and CpG Methylation to Better Predict Humoral Immunity to Influenza Vaccination: Dependence of mRNA-Seq/CpG Methylation on Immune Cell Populations. PMID:28484452
Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy. PMID:28481224
Anti-complement component 5 antibody targeting MG4 domain inhibits choroidal neovascularization. PMID:28477014
FnrL and Three Dnr Regulators Are Used for the Metabolic Adaptation to Low Oxygen Tension in Dinoroseobacter shibae. PMID:28473807
High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure. PMID:28472532
Annotating function to differentially expressed LincRNAs in myelodysplastic syndrome using a network-based method. PMID:28472271
EnHERV: Enrichment analysis of specific human endogenous retrovirus patterns and their neighboring genes. PMID:28472109
CTCF and cohesin regulate chromatin loop stability with distinct dynamics. PMID:28467304
Heat shock and prolonged heat stress attenuate neurotoxin and sporulation gene expression in group I Clostridium botulinum strain ATCC 3502. PMID:28464023
Analysis of the in planta transcriptome expressed by the corn pathogen Pantoea stewartii subsp. stewartii via RNA-Seq. PMID:28462040
Expression profile of mitochondrial voltage-dependent anion channel-1 (VDAC1) influenced genes is associated with pulmonary hypertension. PMID:28461778
Gene expression patterns in the progression of canine copper-associated chronic hepatitis. PMID:28459846
DUX-family transcription factors regulate zygotic genome activation in placental mammals. PMID:28459456
Conservation and innovation in the DUX4-family gene network. PMID:28459454
Responses to Hypoxia and Endoplasmic Reticulum Stress Discriminate the Development of Vitreous and Floury Endosperms of Conventional Maize (Zea mays) Inbred Lines. PMID:28450877
Progressive changes in non-coding RNA profile in leucocytes with age. PMID:28448962
Transcriptional response of Escherichia coli to ammonia and glucose fluctuations. PMID:28447391
Differential host gene responses from infection with neurovirulent and partially-neurovirulent strains of Venezuelan equine encephalitis virus. PMID:28446152
Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity. PMID:28440344
Comprehensive performance comparison of high-resolution array platforms for genome-wide Copy Number Variation (CNV) analysis in humans. PMID:28438122
Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response. PMID:28437467
Identification of NTRK3 Fusions in Childhood Melanocytic Neoplasms. PMID:28433076
Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes. PMID:28427329
Expression of the Maize Dof1 Transcription Factor in Wheat and Sorghum. PMID:28424717
Responses of the Housefly, Musca domestica, to the Hytrosavirus Replication: Impacts on Host's Vitellogenesis and Immunity. PMID:28424677
Deciphering the Regulatory Network between the SREBP Pathway and Protein Secretion in Neurospora crassa. PMID:28420736
Genetic sequence-based prediction of long-range chromatin interactions suggests a potential role of short tandem repeat sequences in genome organization. PMID:28420341
The pathway intermediate 2-keto-3-deoxy-L-galactonate mediates the induction of genes involved in D-galacturonic acid utilization in Aspergillus niger. PMID:28417461
High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia. PMID:28415578
Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection. PMID:28414762
goSTAG: gene ontology subtrees to tag and annotate genes within a set. PMID:28413437
Differential gene expression and transport functionality in the bundle sheath versus mesophyll - a potential role in leaf mineral homeostasis. PMID:28407076
Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease. PMID:28404864
MiRNA profiling of gastrointestinal stromal tumors by next-generation sequencing. PMID:28402935
Nonsense-mediated mRNA decay in Tetrahymena is EJC independent and requires a protozoa-specific nuclease. PMID:28402567
Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis. PMID:28400392
Landscape of histone modifications in a sponge reveals the origin of animal cis-regulatory complexity. PMID:28395144
The integrative omics of white-rot fungus Pycnoporus coccineus reveals co-regulated CAZymes for orchestrated lignocellulose breakdown. PMID:28394946
Profiling transcriptomes of human SH-SY5Y neuroblastoma cells exposed to maleic acid. PMID:28392987
Exploring the differences in metabolic behavior of astrocyte and glioblastoma: a flux balance analysis approach. PMID:28392849
Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response. PMID:28392221
Coordination of Meristem Doming and the Floral Transition by Late Termination, a Kelch Repeat Protein. PMID:28389586
Recognition memory-induced gene expression in the perirhinal cortex: A transcriptomic analysis. PMID:28389337
Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen. PMID:28383283
Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma. PMID:28380458
Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans. PMID:28376087
Comparison of tissue/disease specific integrated networks using directed graphlet signatures. PMID:28361704
Novel therapeutic effects of sesamin on diabetes-induced cardiac dysfunction. PMID:28358428
Computational Analysis of Specific MicroRNA Biomarkers for Noninvasive Early Cancer Detection. PMID:28357401
Time resolved DNA occupancy dynamics during the respiratory oscillation uncover a global reset point in the yeast growth program. PMID:28357254
Transcription factor Etv5 is essential for the maintenance of alveolar type II cells. PMID:28351980
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. PMID:28351387
Modification of the Streptococcus mutans transcriptome by LrgAB and environmental stressors. PMID:28348880
Estimating genome-wide regulatory activity from multi-omics data sets using mathematical optimization. PMID:28347313
WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel. PMID:28345629
A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture. PMID:28343999
Small chromosomal regions position themselves autonomously according to their chromatin class. PMID:28341771
Cross disease analysis of co-functional microRNA pairs on a reconstructed network of disease-gene-microRNA tripartite. PMID:28340554
In silico search for modifier genes associated with pancreatic and liver disease in Cystic Fibrosis. PMID:28339466
Analysis of hepatic transcript profile and plasma lipid profile in early lactating dairy cows fed grape seed and grape marc meal extract. PMID:28335726
The primary transcriptome of Neisseria meningitidis and its interaction with the RNA chaperone Hfq. PMID:28334889
The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis. PMID:28334862
H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements. PMID:28334823
FUNNEL-GSEA: FUNctioNal ELastic-net regression in time-course gene set enrichment analysis. PMID:28334094
Simultaneous analysis of miRNA-mRNA in human meningiomas by integrating transcriptome: A relationship between PTX3 and miR-29c. PMID:28327132
Albugo-imposed changes to tryptophan-derived antimicrobial metabolite biosynthesis may contribute to suppression of non-host resistance to Phytophthora infestans in Arabidopsis thaliana. PMID:28320402
Perturbation of microbiota in one-day old broiler chickens with antibiotic for 24 hours negatively affects intestinal immune development. PMID:28320307
Identification of dysregulated genes in rheumatoid arthritis based on bioinformatics analysis. PMID:28316886
Identification and characterization of a missense mutation in the O-linked β-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability. PMID:28302723
Sex differences in the molecular signature of the developing mouse hippocampus. PMID:28302071
sRNA154 a newly identified regulator of nitrogen fixation in Methanosarcina mazei strain Gö1. PMID:28296572
An Exploration of Charge Compensating Ion Channels across the Phagocytic Vacuole of Neutrophils. PMID:28293191
A comparative analytical assay of gene regulatory networks inferred using microarray and RNA-seq datasets. PMID:28293077
Light Modulates Metabolic Pathways and Other Novel Physiological Traits in the Human Pathogen Acinetobacter baumannii. PMID:28289081
Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E. PMID:28282876
Specific and Novel microRNAs Are Regulated as Response to Fungal Infection in Human Dendritic Cells. PMID:28280489
The within-host dynamics of infection in trans-generationally primed flour beetles. PMID:28277618
miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration. PMID:28276476
De novo computational identification of stress-related sequence motifs and microRNA target sites in untranslated regions of a plant translatome. PMID:28276452
SVMRFE based approach for prediction of most discriminatory gene target for type II diabetes. PMID:28275550
Identifying Novel Transcriptional and Epigenetic Features of Nuclear Lamina-associated Genes. PMID:28273906
Coordination of auxin-triggered leaf initiation by tomato LEAFLESS. PMID:28270611
DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms. PMID:28270217
Rapid Sampling of Escherichia coli After Changing Oxygen Conditions Reveals Transcriptional Dynamics. PMID:28264512
Transcriptional Reprogramming at Genome-Scale of Lactobacillus plantarum WCFS1 in Response to Olive Oil Challenge. PMID:28261192
Gene expression profiling in bladder cancer identifies potential therapeutic targets. PMID:28259975
Prostate apoptosis response 4 (PAR4) expression modulates WNT signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity. PMID:28259909
Two-way learning with one-way supervision for gene expression data. PMID:28257645
Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism. PMID:28257516
Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival. PMID:28252645
Altered regulation and expression of genes by BET family of proteins in COPD patients. PMID:28248992
ZEB1 regulates glioma stemness through LIF repression. PMID:28246407
Cellulose-Derived Oligomers Act as Damage-Associated Molecular Patterns and Trigger Defense-Like Responses. PMID:28242654
Characterization of bovine embryos cultured under conditions appropriate for sustaining human naïve pluripotency. PMID:28241084
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression. PMID:28240248
Asymmetric interactions between doublesex and tissue- and sex-specific target genes mediate sexual dimorphism in beetles. PMID:28239147
Proteome and Secretome Analysis Reveals Differential Post-transcriptional Regulation of Toll-like Receptor Responses. PMID:28235783
MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression. PMID:28232627
Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators. PMID:28228280
Cross-talk between the glucocorticoid receptor and MyoD family inhibitor domain-containing protein provides a new mechanism for generating tissue-specific responses to glucocorticoids. PMID:28223352
Astrocytic Calcium Waves Signal Brain Injury to Neural Stem and Progenitor Cells. PMID:28216142
Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression. PMID:28215940
Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. PMID:28212542
The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system. PMID:28212376
Short-Chain Chitin Oligomers: Promoters of Plant Growth. PMID:28212295
High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection. PMID:28209632
Making life difficult for Clostridium difficile: augmenting the pathogen's metabolic model with transcriptomic and codon usage data for better therapeutic target characterization. PMID:28209199
Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer. PMID:28205582
Pistil Transcriptome Analysis to Disclose Genes and Gene Products Related to Aposporous Apomixis in Hypericum perforatum L. PMID:28203244
Using global gene expression to discriminate thin melanomas with poor outcomes. PMID:28197532
Biocomplexity and Fractality in the Search of Biomarkers of Aging and Pathology: Focus on Mitochondrial DNA and Alzheimer's Disease. PMID:28197358
Transcription Profiling of Bacillus subtilis Cells Infected with AR9, a Giant Phage Encoding Two Multisubunit RNA Polymerases. PMID:28196958
Analysis of miRNA, mRNA, and TF interactions through network-based methods. PMID:28194173
Simultaneous identification of robust synergistic subnetwork markers for effective cancer prognosis. PMID:28194169
Transcriptional Mechanisms of Resistance to Anti-PD-1 Therapy. PMID:28193624
A novel point mutation in RpoB improves osmotolerance and succinic acid production in Escherichia coli. PMID:28193207
A novel RNA sequencing data analysis method for cell line authentication. PMID:28192450
Upregulation of FAM84B during prostate cancer progression. PMID:28186973
An empirically driven data reduction method on the human 450K methylation array to remove tissue specific non-variable CpGs. PMID:28184257
Transcriptomic Profiling of Egg Quality in Sea Bass (Dicentrarchus labrax) Sheds Light on Genes Involved in Ubiquitination and Translation. PMID:28181038
Individualized analysis reveals CpG sites with methylation aberrations in almost all lung adenocarcinoma tissues. PMID:28178989
Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4. PMID:28173143
Unique genetic responses revealed in RNA-seq of the spleen of chickens stimulated with lipopolysaccharide and short-term heat. PMID:28166270
TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice. PMID:28164173
Loss of CD44dim Expression from Early Progenitor Cells Marks T-Cell Lineage Commitment in the Human Thymus. PMID:28163708
Physiological Responses and Gene Co-Expression Network of Mycorrhizal Roots under K+ Deprivation. PMID:28159827
Genome-Wide Transcriptional Start Site Mapping and sRNA Identification in the Pathogen Leptospira interrogans. PMID:28154810
A scalable algorithm for structure identification of complex gene regulatory network from temporal expression data. PMID:28143596
Unsupervised detection of regulatory gene expression information in different genomic regions enables gene expression ranking. PMID:28143396
Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype. PMID:28141856
Impact of Neutron Exposure on Global Gene Expression in a Human Peripheral Blood Model. PMID:28140791
Detecting heterogeneity in single-cell RNA-Seq data by non-negative matrix factorization. PMID:28133571
Vitiligo blood transcriptomics provides new insights into disease mechanisms and identifies potential novel therapeutic targets. PMID:28129744
A Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug Network. PMID:28127549
Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade. PMID:28123870
A systematic comparative evaluation of biclustering techniques. PMID:28114903
Transcriptome profiling of gene expression during immunisation trial against Fasciola hepatica: identification of genes and pathways involved in conferring immunoprotection in a murine model. PMID:28114888
RIsearch2: suffix array-based large-scale prediction of RNA-RNA interactions and siRNA off-targets. PMID:28108657
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains. PMID:28106546
Characterization and in vivo regulon determination of an ECF sigma factor and its cognate anti-sigma factor in Nostoc punctiforme. PMID:28105698
Splenic CD4+ T Cells in Progressive Visceral Leishmaniasis Show a Mixed Effector-Regulatory Phenotype and Impair Macrophage Effector Function through Inhibitory Receptor Expression. PMID:28103263
Role of miR-34a-5p in Hematopoietic Progenitor Cells Proliferation and Fate Decision: Novel Insights into the Pathogenesis of Primary Myelofibrosis. PMID:28098757
MultiDataSet: an R package for encapsulating multiple data sets with application to omic data integration. PMID:28095799
iGC-an integrated analysis package of gene expression and copy number alteration. PMID:28088185
MicroRNA based Pan-Cancer Diagnosis and Treatment Recommendation. PMID:28086747
RYK promotes the stemness of glioblastoma cells via the WNT/ β-catenin pathway. PMID:28086236
Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP. PMID:28085963
Sequential Targeting of CD52 and TNF Allows Early Minimization Therapy in Kidney Transplantation: From a Biomarker to Targeting in a Proof-Of-Concept Trial. PMID:28085915
Vps33b is crucial for structural and functional hepatocyte polarity. PMID:28082148
Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD). PMID:28079125
From the Cover: Embryonic Exposure to TCDD Impacts Osteogenesis of the Axial Skeleton in Japanese medaka, Oryzias latipes. PMID:28077779
Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice. PMID:28077597
Computational Prediction of the Global Functional Genomic Landscape: Applications, Methods, and Challenges. PMID:28076869
Pax-5 is a potent regulator of E-cadherin and breast cancer malignant processes. PMID:28076843
Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia. PMID:28074072
Expression of CD14, IL10, and Tolerogenic Signature in Dendritic Cells Inversely Correlate with Clinical and Immunologic Response to TARP Vaccination in Prostate Cancer Patients. PMID:28073842
Breast Cancer Malignant Processes are Regulated by Pax-5 Through the Disruption of FAK Signaling Pathways. PMID:28070224
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome. PMID:28067246
DNA methylation assessment from human slow- and fast-twitch skeletal muscle fibers. PMID:28057818
Identification of Biomarkers for Breast Cancer Using Databases. PMID:28053957
Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro. PMID:28053000
Linking Hematopoietic Differentiation to Co-Expressed Sets of Pluripotency-Associated and Imprinted Genes and to Regulatory microRNA-Transcription Factor Motifs. PMID:28052084
Batch effects and the effective design of single-cell gene expression studies. PMID:28045081
Novel Biomarker MicroRNAs for Subtyping of Acute Coronary Syndrome: A Bioinformatics Approach. PMID:28044128
Comparative "Omics" of the Fusarium fujikuroi Species Complex Highlights Differences in Genetic Potential and Metabolite Synthesis. PMID:28040774
Quantitative assessment of the diagnostic role of FHIT promoter methylation in non-small cell lung cancer. PMID:28036263
Neuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology. PMID:28035989
Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase. PMID:28035074
PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias. PMID:28025581
Alternative splicing in tomato pollen in response to heat stress. PMID:28025318
Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping. PMID:28024297
Function of AP2/ERF Transcription Factors Involved in the Regulation of Specialized Metabolism in Ophiorrhiza pumila Revealed by Transcriptomics and Metabolomics. PMID:28018397
Changing POU dimerization preferences converts Oct6 into a pluripotency inducer. PMID:28007765
Knowledge-Guided Bioinformatics Model for Identifying Autism Spectrum Disorder Diagnostic MicroRNA Biomarkers. PMID:28000768
Identification of Polycystic Ovary Syndrome (PCOS) Specific Genes in Cumulus and Mural Granulosa Cells. PMID:27997581
Aberrant methylation of CDH13 can be a diagnostic biomarker for lung adenocarcinoma. PMID:27994665
Inducible super-enhancers are organized based on canonical signal-specific transcription factor binding elements. PMID:27994038
Circulating cell-free DNA-based epigenetic assay can detect early breast cancer. PMID:27993161
Exposure of Bacterial Biofilms to Electrical Current Leads to Cell Death Mediated in Part by Reactive Oxygen Species. PMID:27992529
PAX2 function, regulation and targeting in fallopian tube-derived high-grade serous ovarian cancer. PMID:27991925
Gene Expression Correlated with Severe Asthma Characteristics Reveals Heterogeneous Mechanisms of Severe Disease. PMID:27984699
Sepsis Diagnostics: From Discovery to Application. PMID:27984279
Evaluating side effects of nanoparticle-mediated siRNA delivery to mesenchymal stem cells using next generation sequencing and enrichment analysis. PMID:27981244
"Gap hunting" to characterize clustered probe signals in Illumina methylation array data. PMID:27980682
Comparative analyses of super-enhancers reveal conserved elements in vertebrate genomes. PMID:27965291
Prior knowledge guided eQTL mapping for identifying candidate genes. PMID:27964730
Synergistic drug combinations from electronic health records and gene expression. PMID:27940607
Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer. PMID:27935821
Computing and Applying Atomic Regulons to Understand Gene Expression and Regulation. PMID:27933038
Expression of Cav1.3 calcium channel in the human and mouse colon: posttranscriptional inhibition by IFNγ. PMID:27932504
miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling. PMID:27930306
Cellular and molecular characterization of a stem rust resistance locus on wheat chromosome 7AL. PMID:27927228
Transcriptional Network Architecture of Breast Cancer Molecular Subtypes. PMID:27920729
Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines. PMID:27919753
TRPM2 SNP genotype previously associated with susceptibility to Rhodococcus equi pneumonia in Quarter Horse foals displays differential gene expression identified using RNA-Seq. PMID:27919223
Human Intervention Study to Assess the Effects of Supplementation with Olive Leaf Extract on Peripheral Blood Mononuclear Cell Gene Expression. PMID:27918443
Cyanobacteria as Chassis for Industrial Biotechnology: Progress and Prospects. PMID:27916886
Complex genetics architecture contributes to Salmonella resistance in AcB60 mice. PMID:27913859
Chromatin landscapes and genetic risk in systemic lupus. PMID:27906046
Identification of biomarker microRNAs for predicting the response of colorectal cancer to neoadjuvant chemoradiotherapy based on microRNA regulatory network. PMID:27903980
Transcriptomics of Environmental Enrichment Reveals a Role for Retinoic Acid Signaling in Addiction. PMID:27899881
MEF2 transcription factors are key regulators of sprouting angiogenesis. PMID:27898394
EMPOWERING MULTI-COHORT GENE EXPRESSION ANALYSIS TO INCREASE REPRODUCIBILITY. PMID:27896970
Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes. PMID:27895109
Identification of genes and signaling pathways associated with diabetic neuropathy using a weighted correlation network analysis: A consort study. PMID:27893688
Whole-Cell Cancer Vaccines Induce Large Antibody Responses to Carbohydrates and Glycoproteins. PMID:27889407
Time-Course Analysis of Gene Expression During the Saccharomyces cerevisiae Hypoxic Response. PMID:27883312
The microRNA toolkit of insects. PMID:27883064
Three distinct cell populations express extracellular matrix proteins and increase in number during skeletal muscle fibrosis. PMID:27881411
Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. PMID:27880902
High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis. PMID:27876072
Myeloid-Specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF-Dependent Inflammation following Endotoxin Challenge. PMID:27872207
Conservation of immune gene signatures in solid tumors and prognostic implications. PMID:27871313
Dietary Intake Influences Adult Fertility and Offspring Fitness in Zebrafish. PMID:27870856
The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer. PMID:27869162
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors. PMID:27869129
Global transcriptome responses including small RNAs during mixed-species interactions with methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. PMID:27868360
Genome-wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumor suppressor gene in neuroblastoma. PMID:27862318
Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. PMID:27859739
Identification of an Efficient Gene Expression Panel for Glioblastoma Classification. PMID:27855170
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development. PMID:27848968
A meta-analysis of public microarray data identifies gene regulatory pathways deregulated in peripheral blood mononuclear cells from individuals with Systemic Lupus Erythematosus compared to those without. PMID:27846842
GEN3VA: aggregation and analysis of gene expression signatures from related studies. PMID:27846806
Proliferation rates and gene expression profiles in human lymphoblastoid cell lines from patients with depression characterized in response to antidepressant drug therapy. PMID:27845776
Discriminating cancer-related and cancer-unrelated chemoradiation-response genes for locally advanced rectal cancers. PMID:27845363
Integrative analysis of genetic data sets reveals a shared innate immune component in autism spectrum disorder and its co-morbidities. PMID:27842596
VRS2 regulates hormone-mediated inflorescence patterning in barley. PMID:27841879
Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa. PMID:27838510
OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations. PMID:27835869
NUAK1 (ARK5) Is Associated with Poor Prognosis in Ovarian Cancer. PMID:27833898
Arnica montana Stimulates Extracellular Matrix Gene Expression in a Macrophage Cell Line Differentiated to Wound-Healing Phenotype. PMID:27832158
Potential molecular characteristics in situ in response to repetitive UVB irradiation. PMID:27829444
Different tissue phagocytes sample apoptotic cells to direct distinct homeostasis programs. PMID:27828940
Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis. PMID:27825136
Ankyrin-3 as a molecular marker of early-life stress and vulnerability to psychiatric disorders. PMID:27824361
Discovery and replication of a peripheral tissue DNA methylation biosignature to augment a suicide prediction model. PMID:27822318
Group B Streptococcus circumvents neutrophils and neutrophil extracellular traps during amniotic cavity invasion and preterm labor. PMID:27819066
Gene expression profiles and protein-protein interaction networks in amyotrophic lateral sclerosis patients with C9orf72 mutation. PMID:27814735
Integrative analysis for identification of shared markers from various functional cells/tissues for rheumatoid arthritis. PMID:27812736
Comparative Gene Expression Profiling of Primary and Metastatic Renal Cell Carcinoma Stem Cell-Like Cancer Cells. PMID:27812180
Changes in mammary histology and transcriptome profiles by low-dose exposure to environmental phenols at critical windows of development. PMID:27810681
A map of mobile DNA insertions in the NCI-60 human cancer cell panel. PMID:27807467
Transcriptional Analysis of serk1 and serk3 Coreceptor Mutants. PMID:27803191
The Conserved Dcw Gene Cluster of R. sphaeroides Is Preceded by an Uncommonly Extended 5' Leader Featuring the sRNA UpsM. PMID:27802301
Identifying reproducible cancer-associated highly expressed genes with important functional significances using multiple datasets. PMID:27796338
Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats. PMID:27795741
CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins. PMID:27793041
Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation. PMID:27791005
Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse. PMID:27789702
Exploring the intrinsic differences among breast tumor subtypes defined using immunohistochemistry markers based on the decision tree. PMID:27786176
A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. PMID:27782827
CLIP-GENE: a web service of the condition specific context-laid integrative analysis for gene prioritization in mouse TF knockout experiments. PMID:27776539
Computational Analysis of G-Quadruplex Forming Sequences across Chromosomes Reveals High Density Patterns Near the Terminal Ends. PMID:27776185
Gene expression analysis reveals important pathways for drought response in leaves and roots of a wheat cultivar adapted to rainfed cropping in the Cerrado biome. PMID:27768155
Upregulation of HLA Expression in Primary Uveal Melanoma by Infiltrating Leukocytes. PMID:27764126
The Transcriptome of Rhabdomyosarcoma Cells Infected with Cytolytic and Non-Cytolytic Variants of Coxsackievirus B2 Ohio-1. PMID:27760161
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. PMID:27760045
Characterization of Transient Receptor Potential Vanilloid-1 (TRPV1) Variant Activation by Coal Fly Ash Particles and Associations with Altered Transient Receptor Potential Ankyrin-1 (TRPA1) Expression and Asthma. PMID:27758864
Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development. PMID:27757173
RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism. PMID:27754752
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2. PMID:27752141
Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma. PMID:27738108
CNARA: reliability assessment for genomic copy number profiles. PMID:27733115
Comprehensive Cross-Population Analysis of High-Grade Serous Ovarian Cancer Supports No More Than Three Subtypes. PMID:27729437
Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer. PMID:27723779
Convergent transcriptomics and proteomics of environmental enrichment and cocaine identifies novel therapeutic strategies for addiction. PMID:27717806
Exploring timing activation of functional pathway based on differential co-expression analysis in preimplantation embryogenesis. PMID:27705919
Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance. PMID:27705788
Neuronal Splicing Regulator RBFOX3 (NeuN) Regulates Adult Hippocampal Neurogenesis and Synaptogenesis. PMID:27701470
A cytotoxic anti-IL-3Rα antibody targets key cells and cytokines implicated in systemic lupus erythematosus. PMID:27699260
Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata. PMID:27699252
Upregulation of IFN-Inducible and Damage-Response Pathways in Chronic Graft-versus-Host Disease. PMID:27694491
Characterisation of equine satellite cell transcriptomic profile response to β-hydroxy-β-methylbutyrate (HMB). PMID:27691998
A penicillin-binding protein inhibits selection of colistin-resistant, lipooligosaccharide-deficient Acinetobacter baumannii. PMID:27681618
Characterization and phosphoproteomic analysis of a human immortalized podocyte model of Fabry disease generated using CRISPR/Cas9 technology. PMID:27681560
In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state. PMID:27677171
Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction. PMID:27673682
Novel ABCG2 Antagonists Reverse Topotecan-Mediated Chemotherapeutic Resistance in Ovarian Carcinoma Xenografts. PMID:27671528
Characteristics of Pos19 - A Small Coding RNA in the Oxidative Stress Response of Rhodobacter sphaeroides. PMID:27669425
The Challenge of Stability in High-Throughput Gene Expression Analysis: Comprehensive Selection and Evaluation of Reference Genes for BALB/c Mice Spleen Samples in the Leishmania infantum Infection Model. PMID:27668434
Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling. PMID:27668431
Data set for transcriptome analysis of Escherichia coli exposed to nickel. PMID:27668277
Control of Oriented Tissue Growth through Repression of Organ Boundary Genes Promotes Stem Morphogenesis. PMID:27666746
Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth. PMID:27664809
Transcriptomic analysis of the highly efficient oil-degrading bacterium Acinetobacter venetianus RAG-1 reveals genes important in dodecane uptake and utilization. PMID:27664055
Systematically characterizing dysfunctional long intergenic non-coding RNAs in multiple brain regions of major psychosis. PMID:27661005
Detecting cognizable trends of gene expression in a time series RNA-sequencing experiment: a bootstrap approach. PMID:27659329
Trinitrobenzene sulfonic acid-induced intestinal injury in neonatal mice activates transcriptional networks similar to those seen in human necrotizing enterocolitis. PMID:27656771
Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels. PMID:27656675
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function. PMID:27656399
Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma. PMID:27655641
DNA Microarray Platform for Detection and Surveillance of Viruses Transmitted by Small Mammals and Arthropods. PMID:27654806
Global transcriptome dysregulation in second trimester fetuses with FMR1 expansions. PMID:27646161
Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells. PMID:27644592
Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets. PMID:27641228
Functional roles of MMP14 and MMP15 in early postnatal mammary gland development. PMID:27633994
Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways. PMID:27625019
Large-scale microarray profiling reveals four stages of immune escape in non-Hodgkin lymphomas. PMID:27622044
Investigating the Control of Chlorophyll Degradation by Genomic Correlation Mining. PMID:27618630
Portraying breast cancers with long noncoding RNAs. PMID:27617288
Regulatory Cross-Talks and Cascades in Rice Hormone Biosynthesis Pathways Contribute to Stress Signaling. PMID:27617021
Pramipexole induced place preference after L-dopa therapy and nigral dopaminergic loss: linking behavior to transcriptional modifications. PMID:27614895
A robust data scaling algorithm to improve classification accuracies in biomedical data. PMID:27612635
Ultrasonic Surgical Aspirate is a Reliable Source For Culturing Glioblastoma Stem Cells. PMID:27605047
Unbiased identification of signal-activated transcription factors by barcoded synthetic tandem repeat promoter screening (BC-STAR-PROM). PMID:27601530
Cancer Biomarkers from Genome-Scale DNA Methylation: Comparison of Evolutionary and Semantic Analysis Methods. PMID:27600245
Enhancing Interpretability of Gene Signatures with Prior Biological Knowledge. PMID:27600081
Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions. PMID:27598998
A Mycobacterium avium subsp. paratuberculosis Predicted Serine Protease Is Associated with Acid Stress and Intraphagosomal Survival. PMID:27597934
Genotypes of cancer stem cells characterized by epithelial-to-mesenchymal transition and proliferation related functions. PMID:27597445
Identification and Characterization of the Dermal Panniculus Carnosus Muscle Stem Cells. PMID:27594590
Identification of BCL11B as a regulator of adipogenesis. PMID:27586877
Promoter Architecture and Sex-Specific Gene Expression in Daphnia pulex. PMID:27585846
A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals. PMID:27583447
A novel method for the identification of conserved structural patterns in RNA: From small scale to high-throughput applications. PMID:27580722
Epigenetic Loss of MLH1 Expression in Normal Human Hematopoietic Stem Cell Clones is Defined by the Promoter CpG Methylation Pattern Observed by High-Throughput Methylation Specific Sequencing. PMID:27570841
The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress. PMID:27561422
Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map. PMID:27559294
EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks. PMID:27556637
Systematic selection of small molecules to promote differentiation of embryonic stem cells and experimental validation for generating cardiomyocytes. PMID:27551501
fluff: exploratory analysis and visualization of high-throughput sequencing data. PMID:27547532
Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors. PMID:27542283
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma. PMID:27539887
MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy. PMID:27533459
A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts. PMID:27528024
Genome-wide identification of transcriptional start sites in the haloarchaeon Haloferax volcanii based on differential RNA-Seq (dRNA-Seq). PMID:27519343
Transcriptome analysis of copper homeostasis genes reveals coordinated upregulation of SLC31A1,SCO1, and COX11 in colorectal cancer. PMID:27516958
The human olfactory transcriptome. PMID:27515280
Time-course gene expression data on the transcriptional effects of Aminaphtone on ECV304 endothelial cells. PMID:27508230
Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses. PMID:27506674
Regulation of proinflammatory genes by the circulating microRNA hsa-miR-939. PMID:27498764
RNA expression profile of calcified bicuspid, tricuspid, and normal human aortic valves by RNA sequencing. PMID:27495158
A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. PMID:27492330
Backmasking in the yeast genome: encoding overlapping information for protein-coding and RNA degradation. PMID:27492286
White Adipose Tissue Browning in the R6/2 Mouse Model of Huntington's Disease. PMID:27486903
Transcriptomic profile adaptations following exposure of equine satellite cells to nutriactive phytochemical gamma-oryzanol. PMID:27482297
Using ILP to Identify Pathway Activation Patterns in Systems Biology. PMID:27478883
New Cell Adhesion Molecules in Human Ischemic Cardiomyopathy. PCDHGA3 Implications in Decreased Stroke Volume and Ventricular Dysfunction. PMID:27472518
The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection. PMID:27467689
Inverse association between carbohydrate consumption and plasma adropin concentrations in humans. PMID:27460714
Machine Learning of Protein Interactions in Fungal Secretory Pathways. PMID:27441920
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network. PMID:27435189
Coordinate Regulation of Metabolite Glycosylation and Stress Hormone Biosynthesis by TT8 in Arabidopsis. PMID:27432888
Comparison of In Vivo Gene Expression Profiling of RPE/Choroid following Intravitreal Injection of Dexamethasone and Triamcinolone Acetonide. PMID:27429799
Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment - A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 Chemokine. PMID:27428020
Molecular signatures of neural connectivity in the olfactory cortex. PMID:27426965
Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine. PMID:27422173
Regulation of a polyamine transporter by the conserved 3' UTR-derived sRNA SorX confers resistance to singlet oxygen and organic hydroperoxides in Rhodobacter sphaeroides. PMID:27420112
Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways. PMID:27418879
miRNA Profile in Three Different Normal Human Ocular Tissues by miRNA-Seq. PMID:27415791
Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PMID:27414999
Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. PMID:27412481
Obtaining Human Ischemic Stroke Gene Expression Biomarkers from Animal Models: A Cross-species Validation Study. PMID:27407070
The biofilm inhibitor Carolacton inhibits planktonic growth of virulent pneumococci via a conserved target. PMID:27404808
Non-canonical NF-κB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma. PMID:27404455
A consolidated analysis of the physiologic and molecular responses induced under acid stress in the legume-symbiont model-soil bacterium Sinorhizobium meliloti. PMID:27404346
Overcoming the matched-sample bottleneck: an orthogonal approach to integrate omic data. PMID:27403564
Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis. PMID:27401346
Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death. PMID:27399916
NeuroRDF: semantic integration of highly curated data to prioritize biomarker candidates in Alzheimer's disease. PMID:27392431
Algorithms for differential splicing detection using exon arrays: a comparative assessment. PMID:27391904
Non-myogenic tumors display altered expression of dystrophin (DMD) and a high frequency of genetic alterations. PMID:27391342
Transition of an Anaerobic Escherichia coli Culture to Aerobiosis: Balancing mRNA and Protein Levels in a Demand-Directed Dynamic Flux Balance Analysis. PMID:27384956
Embryonic lethal abnormal vision proteins and adenine and uridine-rich element mRNAs after global cerebral ischemia and reperfusion in the rat. PMID:27381823
Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach. PMID:27379244
High-throughput sequencing and de novo transcriptome assembly of Swertia japonica to identify genes involved in the biosynthesis of therapeutic metabolites. PMID:27378356
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins. PMID:27374120
Type IV pili promote early biofilm formation by Clostridium difficile. PMID:27369898
Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways. PMID:27364358
Prior knowledge transfer across transcriptional data sets and technologies using compositional statistics yields new mislabelled ovarian cell line. PMID:27353327
Identification of miRNA/mRNA-Negative Regulation Pairs in Nasopharyngeal Carcinoma. PMID:27350400
Knock-down of the methyltransferase Kmt6 relieves H3K27me3 and results in induction of cryptic and otherwise silent secondary metabolite gene clusters in Fusarium fujikuroi. PMID:27348741
FOXR2 Interacts with MYC to Promote Its Transcriptional Activities and Tumorigenesis. PMID:27346356
Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer. PMID:27330311
Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment? PMID:27328267
A Mechanistic Beta-Binomial Probability Model for mRNA Sequencing Data. PMID:27326762
Transcriptional Profiling of Mycobacterium tuberculosis Exposed to In Vitro Lysosomal Stress. PMID:27324481
Gene expression prediction using low-rank matrix completion. PMID:27317252
AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease. PMID:27312110
Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells. PMID:27307648
What time is it? Deep learning approaches for circadian rhythms. PMID:27307647
The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells. PMID:27299313
A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles. PMID:27295279
Folic acid induces cell type-specific changes in the transcriptome of breast cancer cell lines: a proof-of-concept study. PMID:27293554
Human Argonaute 2 Is Tethered to Ribosomal RNA through MicroRNA Interactions. PMID:27288410
Phorbol ester-mediated re-expression of endogenous LAT adapter in J.CaM2 cells: a model for dissecting drivers and blockers of LAT transcription. PMID:27278128
SSX2 regulates focal adhesion but does not drive the epithelial to mesenchymal transition in prostate cancer. PMID:27276714
Analysis of the Microprocessor in Dictyostelium: The Role of RbdB, a dsRNA Binding Protein. PMID:27272207
Bioinformatics resources for pollen. PMID:27271281
Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection. PMID:27270306
Transcriptomic comparison of Drosophila snRNP biogenesis mutants reveals mutant-specific changes in pre-mRNA processing: implications for spinal muscular atrophy. PMID:27268418
Defining the identity of mouse embryonic dermal fibroblasts. PMID:27265328
Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion. PMID:27264182
Transcriptome Profiling Identifies Multiplexin as a Target of SAGA Deubiquitinase Activity in Glia Required for Precise Axon Guidance During Drosophila Visual Development. PMID:27261002
Selection for reduced translation costs at the intronic 5' end in fungi. PMID:27260512
Breast cancer subtype predictors revisited: from consensus to concordance? PMID:27259591
Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs. PMID:27259276
Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis. PMID:27259231
Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea. PMID:27255285
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants. PMID:27252488
Differences in DNA Repair Capacity, Cell Death and Transcriptional Response after Irradiation between a Radiosensitive and a Radioresistant Cell Line. PMID:27245205
Coronary artery disease susceptibility gene ADTRP regulates cell cycle progression, proliferation, and apoptosis by global gene expression regulation. PMID:27235449
Deleterious assembly of the lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy. PMID:27235420
The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni. PMID:27229370
Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production. PMID:27226058
The Regulation of Cytokine Networks in Hippocampal CA1 Differentiates Extinction from Those Required for the Maintenance of Contextual Fear Memory after Recall. PMID:27224427
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. PMID:27221222
Abundance and Temperature Dependency of Protein-Protein Interaction Revealed by Interface Structure Analysis and Stability Evolution. PMID:27220911
Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis. PMID:27220889
A robust (re-)annotation approach to generate unbiased mappi