IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors
Names
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IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IPD-NHKIR
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Names
More detailed information about this field from each metasource.
IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IPD-NHKIR
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Names
More detailed information about this field from each metasource.
IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IPD-NHKIR
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
The IPD-NHKIR database provides a centralised repository for non-human KIR (NHKIR) sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.
Description
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The IPD-NHKIR database provides a centralised repository for non-human KIR (NHKIR) sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Webpage:
https://www.ebi.ac.uk/ipd/nhkir/Webpage
More detailed information about this field from each metasource.
https://www.ebi.ac.uk/ipd/nhkir/
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Licence:
Name: IPD LicenceLicence name
More detailed information about this field from each metasource.
IPD Licence
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Licence URL
More detailed information about this field from each metasource.
http://www.ebi.ac.uk/ipd/licence.html
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
Nomenclature report for killer-cell immunoglobulin-like receptors (KIR) in macaque species: new genes/alleles, renaming recombinant entities and IPD-NHKIR updates
PMID: 31781789
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
The IPD Project: a centralised resource for the study of polymorphism in genes of the immune system
PMID: 31641782
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications
More detailed information about this field from each metasource.
Nomenclature report for killer-cell immunoglobulin-like receptors (KIR) in macaque species: new genes/alleles, renaming recombinant entities and IPD-NHKIR updates
PMID: 31781789
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
The IPD Project: a centralised resource for the study of polymorphism in genes of the immune system
PMID: 31641782
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
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Nomenclature report for killer-cell immunoglobulin-like receptors (KIR) in macaque species: new genes/alleles, renaming recombinant entities and IPD-NHKIR updates
PubMed citations: 7.
7 articles citing: Nomenclature report for killer-cell immunoglobulin-like receptors (KIR) in macaque species: new genes/alleles, renaming recombinant entities and IPD-NHKIR updates
KIR3DL05 and KIR3DS02 Recognition of a Nonclassical MHC Class I Molecule in the Rhesus Macaque Implicated in Pregnancy Success. PMID:35401580
The Genomic Organization of the LILR Region Remained Largely Conserved Throughout Primate Evolution: Implications for Health And Disease. PMID:34737739
Rapid Characterization of Complex Killer Cell Immunoglobulin-Like Receptor (KIR) Regions Using Cas9 Enrichment and Nanopore Sequencing. PMID:34594334
Rhesus Macaque Activating Killer Immunoglobulin-Like Receptors Associate With Fc Receptor Gamma (FCER1G) and Not With DAP12 Adaptor Proteins Resulting in Stabilized Expression and Enabling Signal Transduction. PMID:33968088
Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility. PMID:33335035
The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates. PMID:33013938
Immunogenetics special issue 2020: nomenclature, databases, and bioinformatics in immunogenetics. PMID:31848642 -
The IPD Project: a centralised resource for the study of polymorphism in genes of the immune system
PubMed citations: 6.
6 articles citing: The IPD Project: a centralised resource for the study of polymorphism in genes of the immune system
Enhanced Extracellular Transfer of HLA-DQ Activates CD3+ Lymphocytes towards Compromised Treg Induction in Celiac Disease. PMID:35682780
Rapid Characterization of Complex Killer Cell Immunoglobulin-Like Receptor (KIR) Regions Using Cas9 Enrichment and Nanopore Sequencing. PMID:34594334
DR2S: an integrated algorithm providing reference-grade haplotype sequences from heterozygous samples. PMID:33971817
Exploiting Tumor Neoantigens to Target Cancer Evolution: Current Challenges and Promising Therapeutic Approaches. PMID:33722796
Haplotype Motif-Based Models for KIR-Genotype Informed Selection of Hematopoietic Cell Donors Fail to Predict Outcome of Patients With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia. PMID:33542712
Immunogenetics special issue 2020: nomenclature, databases, and bioinformatics in immunogenetics. PMID:31848642
Tags:
Tags
More detailed information about this field from each metasource.
deoxyribonucleic acid
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
genetic polymorphism
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
immune system
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
killer-cell immunoglobulin-like receptors
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
multiple sequence alignment
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
nucleic acid sequence alignment
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
sequence alignment
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
polypeptide_region
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Tags
More detailed information about this field from each metasource.
deoxyribonucleic acid
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
genetic polymorphism
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
immune system
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
killer-cell immunoglobulin-like receptors
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
multiple sequence alignment
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
nucleic acid sequence alignment
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
sequence alignment
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
polypeptide_region
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-NHKIR; IPD-NHKIR - Non-Human Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.c3v6e6; Last edited: March 3, 2020, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
dna gene polymorphism immune system killer-cell immunoglobulin-like receptors multiple sequence alignment nucleic acid sequence alignment sequence alignment polypeptide region
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