FAIRsharing.k97xzh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:12 p.m.

Other names: SAM

The Sequence Alignment/Map (SAM) format is a TAB-delimited text format consisting of a header section, which is optional, and an alignment section.

Webpage:

https://github.com/samtools/samtools

Publications:

Publications
More detailed information about this field from each metasource.

The Sequence Alignment/Map format and SAMtools
PMID: 19505943
metasource: Fairsharing.org
version: FAIRsharing.org: SAM; Sequence Alignment Map; DOI: https://doi.org/10.25504/FAIRsharing.k97xzh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:12 p.m.

The Sequence Alignment/Map format and SAMtools PubMed citations: 9999.

9999 articles citing: The Sequence Alignment/Map format and SAMtools

TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells. PMID:35365735
Whole-genome resequencing of Sorghum bicolor and S. bicolor × S. halepense lines provides new insights for improving plant agroecological characteristics. PMID:35365708
Context-dependent DNA polymerization effects can masquerade as DNA modification signals. PMID:35361121
Resequencing and Signatures of Selective Scans Point to Candidate Genetic Variants for Hair Length Traits in Long-Haired and Normal-Haired Tianzhu White Yak. PMID:35360871
Genetics and Plasticity Are Responsible for Ecogeographical Patterns in a Recent Invasion. PMID:35360868
Fine Mapping and Candidate Gene Analysis of BnC08.cds, a Recessive Gene Responsible for Sepal-Specific Chlorophyll-Deficiency in Brassica napus L. PMID:35360306
Insights Into Genome-Wide Association Study for Diabetes: A Bibliometric and Visual Analysis From 2001 to 2021. PMID:35360064
Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma. PMID:35359411
Filamin A Is a Potential Driver of Breast Cancer Metastasis via Regulation of MMP-1. PMID:35359350
The complete chloroplast genome of Atriplex gmelinii C. A. Mey. ex Bong. (Amaranthaceae). PMID:35356788
Tiglon enables accurate transcriptome assembly via integrating mappings of different aligners. PMID:35355524
Chromosomal instability drives convergent and divergent evolution toward advantageous inherited traits in mammalian CHO bioproduction lineages. PMID:35355517
CRISPR Detection and Research on Screening Mutant Gene TTN of Moyamoya Disease Family Based on Whole Exome Sequencing. PMID:35355511
Transcriptional atlas analysis from multiple tissues reveals the expression specificity patterns in beef cattle. PMID:35351103
TargetGeneReg 2.0: a comprehensive web-atlas for p53, p63, and cell cycle-dependent gene regulation. PMID:35350773
Benchmarking the Effectiveness and Accuracy of Multiple Mitochondrial DNA Variant Callers: Practical Implications for Clinical Application. PMID:35350246
Chromosome-length genome assembly and linkage map of a critically endangered Australian bird: the helmeted honeyeater. PMID:35348671
Newcastle disease virus genotype VII gene expression in experimentally infected birds. PMID:35347193
Multi-omics analysis dissects the genetic architecture of seed coat content in Brassica napus. PMID:35346318
Genomic architecture of 5S rDNA cluster and its variations within and between species. PMID:35346033
Diagnostic performance of automated, streamlined, daily updated exome analysis in patients with neurodevelopmental delay. PMID:35346031
In vitro and in silico parameters for precise cgMLST typing of Listeria monocytogenes. PMID:35346021
Dataset for Genome Sequencing and De Novo Assembly of the Candidate Phyla Radiation in Supragingival Plaque. PMID:35345870
Time-Course Transcriptional and Chromatin Accessibility Profiling Reveals Genes Associated With Asymmetrical Gonadal Development in Chicken Embryos. PMID:35345851
Sequencing Reveals Population Structure and Selection Signatures for Reproductive Traits in Yunnan Semi-Fine Wool Sheep (Ovis aries). PMID:35345667
Metagenomic investigation of the equine faecal microbiome reveals extensive taxonomic diversity. PMID:35345588
Mycobacterium tuberculosis transmission in Birmingham, UK, 2009-19: An observational study. PMID:35345560
Plant AFC2 kinase desensitizes thermomorphogenesis through modulation of alternative splicing. PMID:35345463
Decay of TRPV3 as the genomic trace of epidermal structure changes in the land-to-sea transition of mammals. PMID:35342611
Reduced genetic diversity associated with the northern expansion of an amphibian species with high habitat specialization, Ascaphus truei, resolved using two types of genetic markers. PMID:35342604
Low-coverage reduced representation sequencing reveals subtle within-island genetic structure in Aldabra giant tortoises. PMID:35342600
A pipeline for effectively developing highly polymorphic simple sequence repeats markers based on multi-sample genomic data. PMID:35342577
PUMILIO proteins promote colorectal cancer growth via suppressing p21. PMID:35338151
Aegilops sharonensis genome-assisted identification of stem rust resistance gene Sr62. PMID:35338132
Changes in gene body methylation do not correlate with changes in gene expression in Anthozoa or Hexapoda. PMID:35337260
Insights into Gene Transcriptional Regulation of Kayvirus Bacteriophages Obtained from Therapeutic Mixtures. PMID:35337034
Seed Transmission of Three Viruses in Two Pear Rootstock Species Pyrus betulifolia and P. calleryana. PMID:35337008
Discovery of a Novel Species of Trichomonasvirus in the Human Parasite Trichomonas vaginalis Using Transcriptome Mining. PMID:35336955
Complete Genome Sequence of Herpes Simplex Virus 2 Strain G. PMID:35336943
Diversity and Functional Evolution of Terpene Synthases in Rosaceae. PMID:35336617
Novel Salmonella Phage, vB_Sen_STGO-35-1, Characterization and Evaluation in Chicken Meat. PMID:35336181
Whole-Genome Sequencing and Comparative Genomic Analysis of Antimicrobial Producing Streptococcus lutetiensis from the Rumen. PMID:35336126
Legionella pneumophila in Municipal Shower Systems in Stavanger, Norway; A Longitudinal Surveillance Study Using Whole Genome Sequencing in Risk Management. PMID:35336109
Unamplified, Long-Read Metagenomic Sequencing Approach to Close Endosymbiont Genomes of Low-Biomass Insect Populations. PMID:35336091
The ViReflow pipeline enables user friendly large scale viral consensus genome reconstruction. PMID:35332213
MEDUSA: A Pipeline for Sensitive Taxonomic Classification and Flexible Functional Annotation of Metagenomic Shotgun Sequences. PMID:35330728
Diversity of Neofusicoccum parvum for the Production of the Phytotoxic Metabolites (-)-Terremutin and (R)-Mellein. PMID:35330321
Novel Dormancy Mechanism of Castration Resistance in Bone Metastatic Prostate Cancer Organoids. PMID:35328625
Botrytis cinerea Loss and Restoration of Virulence during In Vitro Culture Follows Flux in Global DNA Methylation. PMID:35328468
Fragments of rDNA Genes Scattered over the Human Genome Are Targets of Small RNAs. PMID:35328433
Characterization of Accessible Chromatin Regions in Cattle Rumen Epithelial Tissue during Weaning. PMID:35328088
RNA-Seq Reveals Differentially Expressed Genes Associated with High Fiber Quality in Abaca (Musa textilis Nee). PMID:35328071
The Genome of Rhyzopertha dominica (Fab.) (Coleoptera: Bostrichidae): Adaptation for Success. PMID:35328000
Decoding the Gene Variants of Two Native Probiotic Lactiplantibacillus plantarum Strains through Whole-Genome Resequencing: Insights into Bacterial Adaptability to Stressors and Antimicrobial Strength. PMID:35327997
SINE-Based Phylogenomics Reveal Extensive Introgression and Incomplete Lineage Sorting in Myotis. PMID:35327953
Identification of a Novel FAM83H Mutation and Management of Hypocalcified Amelogenesis Imperfecta in Early Childhood. PMID:35327801
Fine Mapping and Characterization of a Major Gene Responsible for Chlorophyll Biosynthesis in Brassica napus L. PMID:35327594
Side-Directed Release of Differential Extracellular Vesicle-associated microRNA Profiles from Bronchial Epithelial Cells of Healthy and Asthmatic Subjects. PMID:35327424
The Genomics and Population Genomics of the Light Brown Apple Moth, Epiphyas postvittana, an Invasive Tortricid Pest of Horticulture. PMID:35323562
Despite its sequence identity with canonical H4, Drosophila H4r product is enriched at specific chromatin regions. PMID:35322122
High-performance pipeline for MutMap and QTL-seq. PMID:35321412
Molecular Characterization by Multilocus Sequence Typing and Diversity Analysis of Rickettsia asembonensis in Peru. PMID:35319919
A robust mechanism for resetting juvenility during each generation in Arabidopsis. PMID:35318444
Metagenomics reveals global-scale contrasts in nitrogen cycling and cyanobacterial light-harvesting mechanisms in glacier cryoconite. PMID:35317857
Genetic diversity and signatures of selection for heat tolerance and immune response in Iranian native chickens. PMID:35317755
Multi-label classification for multi-drug resistance prediction of Escherichia coli. PMID:35317240
Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression. PMID:35317119
Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA. PMID:35314780
Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites. PMID:35314737
Transposon insertional mutagenesis of diverse yeast strains suggests coordinated gene essentiality polymorphisms. PMID:35314699
High-throughput estimation of allele frequencies using combined pooled-population sequencing and haplotype-based data processing. PMID:35313910
The accessible promoter-mediated supplementary effect of host factors provides new insight into the tropism of SARS-CoV-2. PMID:35313658
Phenotypic and Methylome Responses to Salt Stress in Arabidopsis thaliana Natural Accessions. PMID:35310665
Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires. PMID:35310416
The Easy-to-Use SARS-CoV-2 Assembler for Genome Sequencing: Development Study. PMID:35309411
seGMM: A New Tool for Gender Determination From Massively Parallel Sequencing Data. PMID:35309142
Transcriptome Analysis of Bovine Rumen Tissue in Three Developmental Stages. PMID:35309117
Comparing Long-Read Assemblers to Explore the Potential of a Sustainable Low-Cost, Low-Infrastructure Approach to Sequence Antimicrobial Resistant Bacteria With Oxford Nanopore Sequencing. PMID:35308384
Genome-Wide Transcriptional Response of Mycobacterium smegmatis MC2155 to G-Quadruplex Ligands BRACO-19 and TMPyP4. PMID:35308348
Recurrent allopolyploidization, Y-chromosome introgression and the evolution of sexual systems in the plant genus Mercurialis. PMID:35306889
Evolution of the sex-determining region in Ginkgo biloba. PMID:35306884
Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA. PMID:35306340
Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains. PMID:35304483
The interplay of additivity, dominance, and epistasis on fitness in a diploid yeast cross. PMID:35304450
H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway. PMID:35302840
Targeted introduction of heritable point mutations into the plant mitochondrial genome. PMID:35301443
KPT330 improves Cas9 precision genome- and base-editing by selectively regulating mRNA nuclear export. PMID:35301428
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose. PMID:35301427
Breed dependent regulatory mechanisms of beneficial and non-beneficial fatty acid profiles in subcutaneous adipose tissue in cattle with divergent feed efficiency. PMID:35301378
Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia. PMID:35301312
Comparative Genome Analysis of 'Candidatus Phytoplasma luffae' Reveals the Influential Roles of Potential Mobile Units in Phytoplasma Evolution. PMID:35300489
Metatranscriptomic Analyses Unravel Dynamic Changes in the Microbial and Metabolic Transcriptional Profiles in Artisanal Austrian Hard-Cheeses During Ripening. PMID:35300479
Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases. PMID:35300117
Comprehensive Transcriptome Analysis of GS3 Near-Isogenic Lines During Panicle Development in Rice (Oryza sativa L.). PMID:35299956
Exploration of an XX/XY Sex Determination System and Development of PCR-Based Sex-specific Markers in Procambarus clarkii Based on Next-Generation Sequencing Data. PMID:35299953
Genome-Wide Association Studies Provide Insight Into the Genetic Determination for Hyperpigmentation of the Visceral Peritoneum in Broilers. PMID:35299951
Long-read sequencing reveals the evolutionary drivers of intra-host diversity across natural RNA mycovirus infections. PMID:35299787
Recombination resolves the cost of horizontal gene transfer in experimental populations of Helicobacter pylori. PMID:35298339
Detecting structural variations with precise breakpoints using low-depth WGS data from a single oxford nanopore MinION flowcell. PMID:35296758
Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. PMID:35296311
A new lineage of non-photosynthetic green algae with extreme organellar genomes. PMID:35296310
Extensive evaluation of ATAC-seq protocols for native or formaldehyde-fixed nuclei. PMID:35296236
Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors. PMID:35294956
Experimental evolution links post-transcriptional regulation to Leishmania fitness gain. PMID:35294501
Myosin VI regulates the spatial organisation of mammalian transcription initiation. PMID:35292632
Identification of sex chromosome and sex-determining gene of southern catfish (Silurus meridionalis) based on XX, XY and YY genome sequencing. PMID:35291838
Rapid Decline of Ceftazidime Resistance in Antibiotic-Free and Sublethal Environments Is Contingent on Genetic Background. PMID:35291010
TGFα-EGFR pathway in breast carcinogenesis, association with WWOX expression and estrogen activation. PMID:35290621
High-resolution mapping demonstrates inhibition of DNA excision repair by transcription factors. PMID:35289750
Phylogenomics of the genus Glycine sheds light on polyploid evolution and life-strategy transition. PMID:35288665
PanCancer analysis of somatic mutations in repetitive regions reveals recurrent mutations in snRNA U2. PMID:35288589
Induction of an immortalized songbird cell line allows for gene characterization and knockout by CRISPR-Cas9. PMID:35288582
Rescuing low frequency variants within intra-host viral populations directly from Oxford Nanopore sequencing data. PMID:35288552
MetaPop: a pipeline for macro- and microdiversity analyses and visualization of microbial and viral metagenome-derived populations. PMID:35287721
The Concept of Immunogenetics. PMID:35286690
Transcriptome analysis reveals SALL4 as a prognostic key gene in gastric adenocarcinoma. PMID:35284980
Bulinus truncatus transcriptome - a resource to enable molecular studies of snail and schistosome biology. PMID:35284899
Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): Implications for snail systematics and schistosome epidemiology. PMID:35284876
Mutational characteristics of young and elderly gastric cancer: a comparative study. PMID:35284122
Transcriptomic Analysis Revealed Reactive Oxygen Species Scavenging Mechanisms Associated With Ferrous Iron Toxicity in Aromatic Keteki Joha Rice. PMID:35283928
Oxytetracycline and Streptomycin Resistance Genes in Xanthomonas arboricola pv. pruni, the Causal Agent of Bacterial Spot in Peach. PMID:35283838
Clinical and molecular features of sacrum chordoma in Chinese patients. PMID:35282040
Conserved Regulatory Pathways for Stock-Scion Healing Revealed by Comparative Analysis of Arabidopsis and Tomato Grafting Transcriptomes. PMID:35281699
Temporal regulation of alternative splicing events in rice memory under drought stress. PMID:35281128
Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes. PMID:35279219
Herpesviruses and their genetic diversity in the blood virome of healthy individuals: effect of aging. PMID:35279192
The expanded inhibitor of apoptosis gene family in oysters possesses novel domain architectures and may play diverse roles in apoptosis following immune challenge. PMID:35279090
Dissection of molecular and histological subtypes of papillary thyroid cancer using alternative splicing profiles. PMID:35277656
Loss of the Bardet-Biedl protein Bbs1 alters photoreceptor outer segment protein and lipid composition. PMID:35277505
Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum. PMID:35277503
TIC236 gain-of-function mutations unveil the link between plastid division and plastid protein import. PMID:35275795
GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate. PMID:35275720
Epilepsia Partialis Continua a Clinical Feature of a Missense Variant in the ADCK3 Gene and Poor Response to Therapy. PMID:35275351
Genome-wide SNP and InDel analysis of three Philippine mango species inferred from whole-genome sequencing. PMID:35275322
TAL effectors and the predicted host targets of pomegranate bacterial blight pathogen Xanthomonas citri pv. punicae. PMID:35275250
A Phase II Study of Pembrolizumab in Combination with Capecitabine and Oxaliplatin with Molecular Profiling in Patients with Advanced Biliary Tract Carcinoma. PMID:35274717
Transcriptomic, Proteomic, and Functional Assays Underline the Dual Role of Extrapallial Hemocytes in Immunity and Biomineralization in the Hard Clam Mercenaria mercenaria. PMID:35273613
Prediction of histone post-translational modification patterns based on nascent transcription data. PMID:35273399
The genome of an apodid holothuroid (Chiridota heheva) provides insights into its adaptation to a deep-sea reducing environment. PMID:35273345
In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2. PMID:35273342
Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data. PMID:35273156
Exposure to Trypanosoma parasites induces changes in the microbiome of the Chagas disease vector Rhodnius prolixus. PMID:35272716
Resistomes and microbiome of meat trimmings and colon content from culled cows raised in conventional and organic production systems. PMID:35272712
Adapted laboratory evolution of Thermotoga sp. strain RQ7 under carbon starvation. PMID:35272671
Complex mitogenomic rearrangements within the Pectinidae (Mollusca: Bivalvia). PMID:35272625
Congenital idiopathic megaesophagus in the German shepherd dog is a sex-differentiated trait and is associated with an intronic variable number tandem repeat in Melanin-Concentrating Hormone Receptor 2. PMID:35271580
High-Throughput RNA Sequencing of Mosaic Infected and Non-Infected Apple (Malus × domestica Borkh.) Cultivars: From Detection to the Reconstruction of Whole Genome of Viruses and Viroid. PMID:35270146
Transcriptomic Reprogramming, Alternative Splicing and RNA Methylation in Potato (Solanum tuberosum L.) Plants in Response to Potato Virus Y Infection. PMID:35270104
Stress Reactivity, Susceptibility to Hypertension, and Differential Expression of Genes in Hypertensive Compared to Normotensive Patients. PMID:35269977
Dek504 Encodes a Mitochondrion-Targeted E+-Type Pentatricopeptide Repeat Protein Essential for RNA Editing and Seed Development in Maize. PMID:35269656
The Cell Membrane of a Novel Rhizobium phaseoli Strain Is the Crucial Target for Aluminium Toxicity and Tolerance. PMID:35269493
Insights into the Histone Acetylation-Mediated Regulation of the Transcription Factor Genes That Control the Embryogenic Transition in the Somatic Cells of Arabidopsis. PMID:35269485
Estimates of Effective Population Size in Commercial and Hatchery Strains of Coho Salmon (Oncorhynchus kisutch (Walbaum, 1792)). PMID:35268215
Circulating Cell-Free DNA Reflects the Clonal Evolution of Breast Cancer Tumors. PMID:35267640
Chromosome-level genome assembly of a xerophytic plant, Haloxylon ammodendron. PMID:35266513
Whole-genome sequencing reveals novel ethnicity-specific rare variants associated with Alzheimer's disease. PMID:35264725
Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. PMID:35264582
A large and diverse autosomal haplotype is associated with sex-linked colour polymorphism in the guppy. PMID:35264556
Agrobacterium species bacteraemia, Switzerland, 2008 to 2019: a molecular epidemiological study. PMID:35264215
Genome-wide identification and characterization of Fusarium circinatum-responsive lncRNAs in Pinus radiata. PMID:35264109
Detection of a major QTL and development of KASP markers for seed weight by combining QTL-seq, QTL-mapping and RNA-seq in peanut. PMID:35262768
Single base mutations in the nucleocapsid gene of SARS-CoV-2 affects amplification efficiency of sequence variants and may lead to assay failure. PMID:35262020
Investigating underlying human immunity genes, implicated diseases and their relationship to COVID-19. PMID:35261286
Mass COVID-19 patient screening using UvsX and UvsY mediated DNA recombination and high throughput parallel sequencing. PMID:35260723
Mechanosensory trichome cells evoke a mechanical stimuli-induced immune response in Arabidopsis thaliana. PMID:35260555
Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors. PMID:35260549
Co-expression network analyses of anthocyanin biosynthesis genes in Ruellia (Wild Petunias; Acanthaceae). PMID:35260074
Long-distance dispersal of pigeons and doves generated new ecological opportunities for host-switching and adaptive radiation by their parasites. PMID:35259992
Geographically dispersed zoonotic tuberculosis in pre-contact South American human populations. PMID:35256608
Reducing N6AMT1-mediated 6mA DNA modification promotes breast tumor progression via transcriptional repressing cell cycle inhibitors. PMID:35256595
The microbiome and resistome of apple fruits alter in the post-harvest period. PMID:35256002
The VIL gene CRAWLING ELEPHANT controls maturation and differentiation in tomato via polycomb silencing. PMID:35255095
Model-based identification of conditionally-essential genes from transposon-insertion sequencing data. PMID:35255084
Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources. PMID:35255079
Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study. PMID:35252901
Fusobacterium nucleatum is associated with inflammation and poor survival in early-stage HPV-negative tongue cancer. PMID:35252868
Integrated Chromatin Accessibility and Transcriptome Landscapes of 5-Fluorouracil-Resistant Colon Cancer Cells. PMID:35252200
Case Report: Genetic Analysis of a Small Supernumerary Marker Chromosome in a Unique Case of Mosaic Turner Syndrome. PMID:35252057
Targeted Deletion of Centrin in Leishmania braziliensis Using CRISPR-Cas9-Based Editing. PMID:35252020
Fusion Gene Detection Using Whole-Exome Sequencing Data in Cancer Patients. PMID:35251131
Map-Based Cloning and Characterization of Br-dyp1, a Gene Conferring Dark Yellow Petal Color Trait in Chinese Cabbage (Brassica rapa L. ssp. pekinensis). PMID:35251110
Microautophagy Mediates Vacuolar Delivery of Storage Proteins in Maize Aleurone Cells. PMID:35251104
Genomic Data Reveals Population Genetic and Demographic History of Magnolia fistulosa (Magnoliaceae), a Plant Species With Extremely Small Populations in Yunnan Province, China. PMID:35251084
Transfer of the Dominant Virus Resistance Gene AV-1 pro From Asparagus prostratus to Chromosome 2 of Garden Asparagus A. officinalis L. PMID:35251064
Heterosis Derived From Nonadditive Effects of the BnFLC Homologs Coordinates Early Flowering and High Yield in Rapeseed (Brassica napus L.). PMID:35251061
Decoding Human Genome Regulatory Features That Influence HIV-1 Proviral Expression and Fate Through an Integrated Genomics Approach. PMID:35250265
Linking genome wide RNA sequencing with physio-biochemical and cytological responses to catalogue key genes and metabolic pathways for alkalinity stress tolerance in lentil (Lens culinaris Medikus). PMID:35247970
CNVind: an open source cloud-based pipeline for rare CNVs detection in whole exome sequencing data based on the depth of coverage. PMID:35247967
Allele-specific expression reveals genes with recurrent cis-regulatory alterations in high-risk neuroblastoma. PMID:35246212
Cell type-specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis. PMID:35245111
Genetic mapping of powdery mildew resistance genes in wheat landrace Guizi 1 via genotyping by sequencing. PMID:35244868
Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use. PMID:35244186
Population-Genomic Analysis Identifies a Low Rate of Global Adaptive Fixation in the Proteins of the Cyclical Parthenogen Daphnia magna. PMID:35244177
Generation of a pooled shRNA library for functional genomics screens. PMID:35243374
Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells. PMID:35243263
Mapping and CRISPR homology-directed repair of a recessive white eye mutation in Plodia moths. PMID:35243245
Regulatory perturbations of ribosome allocation in bacteria reshape the growth proteome with a trade-off in adaptation capacity. PMID:35243241
Transcriptomic data of MCF-7 breast cancer cells treated with G1, a G-protein coupled estrogen receptor (GPER) agonist. PMID:35242930
Comparative Genomics and Characterization of SARS-CoV-2 P.1 (Gamma) Variant of Concern From Amazonas, Brazil. PMID:35242782
Limited genomic reconstruction of SARS-CoV-2 transmission history within local epidemiological clusters. PMID:35242361
Targeted Re-Sequencing of the 2p21 Locus Identifies Non-Syndromic Cleft Lip Only Novel Susceptibility Gene ZFP36L2. PMID:35242166
CG and CHG Methylation Contribute to the Transcriptional Control of OsPRR37-Output Genes in Rice. PMID:35242159
Identification of antimicrobial peptides from the human gut microbiome using deep learning. PMID:35241840
Chromosome-scale and haplotype-resolved genome assembly of a tetraploid potato cultivar. PMID:35241824
Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma. PMID:35241665
Antibody escape and global spread of SARS-CoV-2 lineage A.27. PMID:35241661
Comparative genomics of plant pathogenic Diaporthe species and transcriptomics of Diaporthe caulivora during host infection reveal insights into pathogenic strategies of the genus. PMID:35240994
Multiple knockout mutants reveal a high redundancy of phytotoxic compounds contributing to necrotrophic pathogenesis of Botrytis cinerea. PMID:35239739
Genome-Wide Association Study-Guided Exome Rare Variant Burden Analysis Identifies IL1R1 and CD3E as Potential Autoimmunity Risk Genes for Celiac Disease. PMID:35237542
Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis. PMID:35236861
Short-read and long-read full-length transcriptome of mouse neural stem cells across neurodevelopmental stages. PMID:35236860
Two zinc finger proteins with functions in m6A writing interact with HAKAI. PMID:35236848
Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells. PMID:35236847
Molecular detection of a novel Ancylostoma sp. by whole mtDNA sequence from pangolin Manis javanica. PMID:35236404
Lack of food intake during shift work alters the heart transcriptome and leads to cardiac tissue fibrosis and inflammation in rats. PMID:35236346
Phylogeny, diversification, and biogeography of a hemiclonal hybrid system of native Australian freshwater fishes (Gobiiformes: Gobioidei: Eleotridae: Hypseleotris). PMID:35236294
Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure. PMID:35235788
Novel mutation in hexokinase 2 confers resistance to 2-deoxyglucose by altering protein dynamics. PMID:35235554
The Runaway Evolution of SARS-CoV-2 Leading to the Highly Evolved Delta Strain. PMID:35234869
Characterization and Demonstration of Mock Communities as Control Reagents for Accurate Human Microbiome Community Measurements. PMID:35234490
Multi-population puma connectivity could restore genomic diversity to at-risk coastal populations in California. PMID:35233248
Differential expression analyses reveal extensive transcriptional plasticity induced by temperature in New Zealand silver trevally (Pseudocaranx georgianus). PMID:35233245
Preterm birth buccal cell epigenetic biomarkers to facilitate preventative medicine. PMID:35232984
Distribution and regulatory roles of oxidized 5-methylcytosines in DNA and RNA of the basidiomycete fungi Laccaria bicolor and Coprinopsis cinerea. PMID:35232254
CYP2D6 gene resequencing in the Malagasy, a population at the crossroads between Asia and Africa: a pilot study. PMID:35230160
Stimulated Organic Carbon Cycling and Microbial Community Shift Driven by a Simulated Cold-Seep Eruption. PMID:35229641
Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology. PMID:35229638
Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei. PMID:35229632
Intra-specific copy number variation of MHC class II genes in the Siamese fighting fish. PMID:35229174
Efficient targeted insertion of large DNA fragments without DNA donors. PMID:35228726
An engineered bispecific human monoclonal antibody against SARS-CoV-2. PMID:35228696
HiCBin: binning metagenomic contigs and recovering metagenome-assembled genomes using Hi-C contact maps. PMID:35227283
Novel long non-coding RNAs of relevance for ulcerative colitis pathogenesis. PMID:35224318
Monocyte and Macrophage Lipid Accumulation Results in Down-Regulated Type-I Interferon Responses. PMID:35224060
Proteomic Signatures of Antimicrobial Resistance in Yersinia pestis and Francisella tularensis. PMID:35223919
Neoantigen Quantity and Quality in Relation to Pancreatic Cancer Survival. PMID:35223878
Comparative analysis of differential gene expression indicates divergence in ontogenetic strategies of leaves in two conifer genera. PMID:35222971
Admixture in Africanized honey bees (Apis mellifera) from Panamá to San Diego, California (U.S.A.). PMID:35222958
Stromal Protein Chloroplast Development and Biogenesis1 Is Essential for Chloroplast Development and Biogenesis in Arabidopsis thaliana. PMID:35222475
Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization. PMID:35221334
Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis. PMID:35219383
Rational and evolutionary engineering of Saccharomyces cerevisiae for production of dicarboxylic acids from lignocellulosic biomass and exploring genetic mechanisms of the yeast tolerance to the biomass hydrolysate. PMID:35219341
A new lineage of Galapagos giant tortoises identified from museum samples. PMID:35217806
An in-frame deletion mutation in the degron tail of auxin coreceptor IAA2 confers resistance to the herbicide 2,4-D in Sisymbrium orientale. PMID:35217601
Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9. PMID:35217600
8C-like cells capture the human zygotic genome activation program in vitro. PMID:35216671
Integrative Genomic and Transcriptomic Profiling Reveals a Differential Molecular Signature in Uterine Leiomyoma versus Leiomyosarcoma. PMID:35216305
SARS-CoV-2 Delta Variant (AY.3) in the Feces of a Domestic Cat. PMID:35216014
Clinical Tick-Borne Encephalitis in a Roe Deer (Capreolus capreolus L.). PMID:35215891
Bacteriophages Roam the Wheat Phyllosphere. PMID:35215838
ViralFlow: A Versatile Automated Workflow for SARS-CoV-2 Genome Assembly, Lineage Assignment, Mutations and Intrahost Variant Detection. PMID:35215811
Neutralization of SARS-CoV-2 Variants by rVSV-ΔG-Spike-Elicited Human Sera. PMID:35214749
Gene-rich germline-restricted chromosomes in black-winged fungus gnats evolved through hybridization. PMID:35213540
CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells. PMID:35212377
Characterizing mobile element insertions in 5675 genomes. PMID:35212372
SAM-TB: a whole genome sequencing data analysis website for detection of Mycobacterium tuberculosis drug resistance and transmission. PMID:35211720
Screening and Verification of Molecular Markers and Genes Related to Salt-Alkali Tolerance in Portunus trituberculatus. PMID:35211153
A Chromosome-Level Genome Assembly of the European Beech (Fagus sylvatica) Reveals Anomalies for Organelle DNA Integration, Repeat Content and Distribution of SNPs. PMID:35211148
Cellular fractionation reveals transcriptome responses of human fibroblasts to UV-C irradiation. PMID:35210409
Evaluation of four methods to identify the homozygotic sex chromosome in small populations. PMID:35209843
Transcriptomic Analysis of Degradative Pathways for Azo Dye Acid Blue 113 in Sphingomonas melonis B-2 from the Dye Wastewater Treatment Process. PMID:35208892
Identification and Validation of Ikaros (IKZF1) as a Cancer Driver Gene for Marek's Disease Virus-Induced Lymphomas. PMID:35208856
RNA Sequencing Reveals Widespread Transcription of Natural Antisense RNAs in Entamoeba Species. PMID:35208849
Comparison of Reference-Based Assembly and De Novo Assembly for Bacterial Plasmid Reconstruction and AMR Gene Localization in Salmonella enterica Serovar Schwarzengrund Isolates. PMID:35208682
Novel KLK4 Mutations Cause Hypomaturation Amelogenesis Imperfecta. PMID:35207639
Transcriptome Analysis of Halotolerant Staphylococcus saprophyticus Isolated from Korean Fermented Shrimp. PMID:35206000
Snapshot of Mycobacterium tuberculosis Phylogenetics from an Indian State of Arunachal Pradesh Bordering China. PMID:35205308
Genomic Diversity Profiling and Breed-Specific Evolutionary Signatures of Selection in Arunachali Yak. PMID:35205299
Genomic Hatchery Introgression in Brown Trout (Salmo trutta L.): Development of a Diagnostic SNP Panel for Monitoring the Impacted Mediterranean Rivers. PMID:35205298
Y-Chromosomal Insights into Breeding History and Sire Line Genealogies of Arabian Horses. PMID:35205275
Conservation Genomics of Two Threatened Subspecies of Northern Giraffe: The West African and the Kordofan Giraffe. PMID:35205265
miRNA-Mediated Priming of Macrophage M1 Differentiation Differs in Gram-Positive and Gram-Negative Settings. PMID:35205256
Improved DNA Extraction and Illumina Sequencing of DNA Recovered from Aged Rootless Hair Shafts Found in Relics Associated with the Romanov Family. PMID:35205247
Combining Fine Mapping, Whole-Genome Re-Sequencing, and RNA-Seq Unravels Candidate Genes for a Soybean Mutant with Short Petioles and Weakened Pulvini. PMID:35205230
Population Structure and Diversity in European Honey Bees (Apismellifera L.)-An Empirical Comparison of Pool and Individual Whole-Genome Sequencing. PMID:35205227
Epigenomic Modifications in Modern and Ancient Genomes. PMID:35205223
Population Genomics of Megalobrama Provides Insights into Evolutionary History and Dietary Adaptation. PMID:35205053
Alterations of the Gut Microbiome Associated to Methane Metabolism in Mexican Children with Obesity. PMID:35204867
Novel Genetic Prognostic Signature for Lung Adenocarcinoma Identified by Differences in Gene Expression Profiles of Low- and High-Grade Histological Subtypes. PMID:35204661
Genomic Analysis of ESBL-Producing E. coli in Wildlife from North-Eastern Germany. PMID:35203726
Spatial and Genomic Correlates of HIV-1 Integration Site Targeting. PMID:35203306
Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development. PMID:35198906
Spotlight on alternative frame coding: Two long overlapping genes in Pseudomonas aeruginosa are translated and under purifying selection. PMID:35198897
An intraspecies Leishmania donovani hybrid from the Indian subcontinent is associated with an atypical phenotype of cutaneous disease. PMID:35198868
High rate of reinfection and possible transmission of Mycobacterium avium complex in Northeast Thailand. PMID:35198722
Comprehensive characterization of the epigenetic landscape in Multiple Myeloma. PMID:35198065
Single Nucleotide Polymorphism Detection for Peach Gummosis Disease Resistance by Genome-Wide Association Study. PMID:35197988
Seroprevalence, Prevalence, and Genomic Surveillance: Monitoring the Initial Phases of the SARS-CoV-2 Pandemic in Betim, Brazil. PMID:35197952
Analysis of SARS-CoV-2 Variants From 24,181 Patients Exemplifies the Role of Globalization and Zoonosis in Pandemics. PMID:35197938
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. PMID:35197628
Combined use of Oxford Nanopore and Illumina sequencing yields insights into soybean structural variation biology. PMID:35197050
High Prevalence and Diversity of Caliciviruses in a Community Setting Determined by a Metagenomic Approach. PMID:35196791
A decade of stability for wMel Wolbachia in natural Aedes aegypti populations. PMID:35196357
Combining explainable machine learning, demographic and multi-omic data to inform precision medicine strategies for inflammatory bowel disease. PMID:35196350
Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer. PMID:35194151
Genome-wide diversity analysis to infer population structure and linkage disequilibrium among Colombian coconut germplasm. PMID:35194112
Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4. PMID:35194019
Systematic benchmark of state-of-the-art variant calling pipelines identifies major factors affecting accuracy of coding sequence variant discovery. PMID:35193511
SEAseq: a portable and cloud-based chromatin occupancy analysis suite. PMID:35193506
Phylogeography and transmission of M. tuberculosis in Moldova: A prospective genomic analysis. PMID:35192619
The noncoding RNA CcnA modulates the master cell cycle regulators CtrA and GcrA in Caulobacter crescentus. PMID:35192605
Epigenetic reprogramming by TET enzymes impacts co-transcriptional R-loops. PMID:35191837
Genomic characterization of the world's longest selection experiment in mouse reveals the complexity of polygenic traits. PMID:35189878
Genome-wide investigation of the ZF-HD gene family in two varieties of alfalfa (Medicago sativa L.) and its expression pattern under alkaline stress. PMID:35189832
Circulation, genomic characteristics, and evolutionary dynamics of class I Newcastle disease virus in China. PMID:35188866
STAT3-mediated allelic imbalance of novel genetic variant Rs1047643 and B-cell-specific super-enhancer in association with systemic lupus erythematosus. PMID:35188103
Application of ATAC-Seq for genome-wide analysis of the chromatin state at single myofiber resolution. PMID:35188098
Extracellular Vesicles Derived From Human Corneal Endothelial Cells Inhibit Proliferation of Human Corneal Endothelial Cells. PMID:35186961
Profiling Selective Packaging of Host RNA and Viral RNA Modification in SARS-CoV-2 Viral Preparations. PMID:35186917
Complete Genome Sequencing and Comparative Analysis of the Clinically-Derived Apiotrichum mycotoxinivorans Strain GMU1709. PMID:35186802
Phylogenomics and Biogeography of Populus Based on Comprehensive Sampling Reveal Deep-Level Relationships and Multiple Intercontinental Dispersals. PMID:35185985
TC-hunter: identification of the insertion site of a transgenic gene within the host genome. PMID:35184734
Sperm histone H3 lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction. PMID:35183795
Identification of quantitative trait loci (QTLs) and candidate genes of seed Iron and zinc content in soybean [Glycine max (L.) Merr.]. PMID:35183125
EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells. PMID:35182476
RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation. PMID:35181706
Genome binning of viral entities from bulk metagenomics data. PMID:35181661
Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia. PMID:35180380
Advances in lentil production through heterosis: Evaluating generations and breeding systems. PMID:35180225
Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2. PMID:35179717
Chromosome-scale assembly and population diversity analyses provide insights into the evolution of Sapindus mukorossi. PMID:35178562
Sentinel Surveillance Reveals Emerging Daptomycin-Resistant ST736 Enterococcus faecium and Multiple Mechanisms of Linezolid Resistance in Enterococci in the United States. PMID:35178041
Whole genome resequencing data enables a targeted SNP panel for conservation and aquaculture of Oreochromis cichlid fishes. PMID:35177872
Population genomic signatures of the oriental fruit moth related to the Pleistocene climates. PMID:35177826
Supergene origin and maintenance in Atlantic cod. PMID:35177802
Detecting SARS-CoV-2 lineages and mutational load in municipal wastewater and a use-case in the metropolitan area of Thessaloniki, Greece. PMID:35177697
Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium. PMID:35177608
GCAT|Panel, a comprehensive structural variant haplotype map of the Iberian population from high-coverage whole-genome sequencing. PMID:35176773
Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories. PMID:35176234
Unveiling forensically relevant biogeographic, phenotype and Y-chromosome SNP variation in Pakistani ethnic groups using a customized hybridisation enrichment forensic intelligence panel. PMID:35176104
Tool evaluation for the detection of variably sized indels from next generation whole genome and targeted sequencing data. PMID:35176018
Blood and brain gene expression signatures of chronic intermittent ethanol consumption in mice. PMID:35176017
Closed Genome Sequences of Providencia alcalifaciens Isolates from Dogs. PMID:35175129
A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis. PMID:35174975
Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial. PMID:35173154
METABOLIC: high-throughput profiling of microbial genomes for functional traits, metabolism, biogeochemistry, and community-scale functional networks. PMID:35172890
Worldwide SARS-CoV-2 haplotype distribution in early pandemic. PMID:35171928
Detection of SARS-CoV-2 Omicron variant (B.1.1.529) infection of white-tailed deer. PMID:35169802
Strong selection and high mutation supply characterize experimental Chlorovirus evolution. PMID:35169490
Butterfly eyespots evolved via cooption of an ancestral gene-regulatory network that also patterns antennae, legs, and wings. PMID:35169073
Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. PMID:35168652
Investigation and characterization of human gut phageome in advanced liver cirrhosis of defined etiologies. PMID:35168645
Functional genomics elucidates regulatory mechanisms of Parkinson's disease-associated variants. PMID:35168626
Comparative transcriptome analysis identifies crucial candidate genes and pathways in the hypothalamic-pituitary-gonadal axis during external genitalia development of male geese. PMID:35168567
Global pleiotropic effects in adaptively evolved Escherichia coli lacking CRP reveal molecular mechanisms that define the growth physiology. PMID:35167766
Cryptic MYC insertions in Burkitt lymphoma: New data and a review of the literature. PMID:35167621
Endogenous retroviruses co-opted as divergently transcribed regulatory elements shape the regulatory landscape of embryonic stem cells. PMID:35166831
Genomic and phenotypic analyses of diverse non-clinical Acinetobacter baumannii strains reveals strain-specific virulence and resistance capacity. PMID:35166651
Fully resolved assembly of Cryptosporidium parvum. PMID:35166336
Integrated single-cell multiomics analysis reveals novel candidate markers for prognosis in human pancreatic ductal adenocarcinoma. PMID:35165277
Evolution of biofilm-adapted gene expression profiles in lasR-deficient clinical Pseudomonas aeruginosa isolates. PMID:35165270
Stabilizing selection on Atlantic cod supergenes through a millennium of extensive exploitation. PMID:35165196
Molecular parallelism in signaling function across different sexually selected ornaments in a warbler. PMID:35165176
Human BRCA pathogenic variants were originated during recent human history. PMID:35165121
Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum). PMID:35164736
Whole-genome resequencing of Coffea arabica L. (Rubiaceae) genotypes identify SNP and unravels distinct groups showing a strong geographical pattern. PMID:35164709
Benchmarking phasing software with a whole-genome sequenced cattle pedigree. PMID:35164677
gcaPDA: a haplotype-resolved diploid assembler. PMID:35164674
CRP-Like Transcriptional Regulator MrpC Curbs c-di-GMP and 3',3'-cGAMP Nucleotide Levels during Development in Myxococcus xanthus. PMID:35164555
Carbon Catabolite Repression Governs Diverse Physiological Processes and Development in Aspergillus nidulans. PMID:35164551
Epithelial Cell-Derived Extracellular Vesicles Trigger the Differentiation of Two Epithelial Cell Lines. PMID:35163646
Long Non-Coding RNA LINC02802 Regulates In Vitro Sprouting Angiogenesis by Sponging microRNA-486-5p. PMID:35163581
Whole-Genome Sequencing and RNA-Seq Reveal Differences in Genetic Mechanism for Flowering Response between Weedy Rice and Cultivated Rice. PMID:35163531
Combining Metabolomics and Experimental Evolution Reveals Key Mechanisms Underlying Longevity Differences in Laboratory Evolved Drosophila melanogaster Populations. PMID:35162994
Association of Tandem Repeat Number Variabilities in Subunit S of the Type I Restriction-Modification System with Macrolide Resistance in Mycoplasma pneumoniae. PMID:35160167
Are Cell Junctions Implicated in the Regulation of Vitellogenin Uptake? Insights from an RNAseq-Based Study in Eel, Anguilla australis. PMID:35159359
Neurodevelopmental Syndrome with Intellectual Disability, Speech Impairment, and Quadrupedia Is Associated with Glutamate Receptor Delta 2 Gene Defect. PMID:35159210
Identification of Early-Onset Metastasis in SF3B1 Mutated Uveal Melanoma. PMID:35159112
Selection and Drift: A Comparison between Historic and Recent Dutch Friesian Cattle and Recent Holstein Friesian Using WGS Data. PMID:35158654
F0F1-ATPase Contributes to the Fluoride Tolerance and Cariogenicity of Streptococcus mutans. PMID:35173687
Mutation Characteristics and Phylogenetic Analysis of Five Leishmania Clinical Isolates. PMID:35158645
SARS-CoV-2 accessory protein ORF8 is secreted extracellularly as a glycoprotein homodimer. PMID:35157849
Post-insemination selection dominates pre-insemination selection in driving rapid evolution of male competitive ability. PMID:35157717
Evolution of cefiderocol resistance in Stenotrophomonas maltophilia using in vitro serial passage techniques. PMID:35156034
HKG: an open genetic variant database of 205 Hong Kong cantonese exomes. PMID:35156024
An improved molecular inversion probe based targeted sequencing approach for low variant allele frequency. PMID:35156021
Genomic and Virological Characterization of SARS-CoV-2 Variants in a Subset of Unvaccinated and Vaccinated U.S. Military Personnel. PMID:35155489
Neutral and adaptive drivers of genomic change in introduced brook trout (Salvelinus fontinalis) populations revealed by pooled sequencing. PMID:35154655
Potential Mechanisms of Quercetin Influence the ClfB Protein During Biofilm Formation of Staphylococcus aureus. PMID:35153795
Genomic architecture of phenotypic extremes in a wild cervid. PMID:35151275
Putative variants, genetic diversity and population structure among Soybean cultivars bred at different ages in Huang-Huai-Hai region. PMID:35149770
Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage. PMID:35148836
Osmotic stress induces long-term biofilm survival in Liberibacter crescens. PMID:35148684
Tcf12 and NeuroD1 cooperatively drive neuronal migration during cortical development. PMID:35147187
Extracellular electron transfer increases fermentation in lactic acid bacteria via a hybrid metabolism. PMID:35147079
Whole genome re-sequencing reveals the genetic diversity and evolutionary patterns of Eucommia ulmoides. PMID:35146538
Developmental alterations in DNA methylation during gametogenesis from primordial germ cells to sperm. PMID:35146397
Hybridization underlies localized trait evolution in cavefish. PMID:35146393
SkewC: Identifying cells with skewed gene body coverage in single-cell RNA sequencing data. PMID:35146392
Optimization of Ribosome Footprinting Conditions for Ribo-Seq in Human and Drosophila melanogaster Tissue Culture Cells. PMID:35145996
Further Delineation of the Spectrum of XMEN Disease in Six Chinese Pediatric Patients. PMID:35145548
CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters. PMID:35145304
Modulation of microbial community dynamics by spatial partitioning. PMID:35145274
The microbiome of the buffalo digestive tract. PMID:35145088
Integrative analysis reveals multiple modes of LXR transcriptional regulation in liver. PMID:35145035
A SARS-CoV-2 Delta variant containing mutation in the probe binding region used for RT-qPCR test in Japan exhibited atypical PCR amplification and might induce false negative result. PMID:35144878
Long-read sequencing of the zebrafish genome reorganizes genomic architecture. PMID:35144548
High Stability of the Epigenome in Drosophila Interspecific Hybrids. PMID:35143649
New Insights into Mitochondrial-Nuclear Interactions Revealed through Analysis of Small RNAs. PMID:35143645
Multiple phylogenetically-diverse, differentially-virulent Burkholderia pseudomallei isolated from a single soil sample collected in Thailand. PMID:35143500
Genomic legacy of migration in endangered caribou. PMID:35143486
Haplotype mapping uncovers unexplored variation in wild and domesticated soybean at the major protein locus cqProt-003. PMID:35141762
Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome. PMID:35140888
Oceanic Crustal Fluid Single Cell Genomics Complements Metagenomic and Metatranscriptomic Surveys With Orders of Magnitude Less Sample Volume. PMID:35140689
Clinical and pathological characteristics associated with the presence of the IS6110 Mycobacterim tuberculosis transposon in neoplastic cells from non-small cell lung cancer patients. PMID:35140255
Transcriptional landscape of circulating platelets from patients with COVID-19 reveals key subnetworks and regulators underlying SARS-CoV-2 infection: implications for immunothrombosis. PMID:35139909
Small RNAs mediate transgenerational inheritance of genome-wide trans-acting epialleles in maize. PMID:35139883
Genome sequencing-based coverage analyses facilitate high-resolution detection of deletions linked to phenotypes of gamma-irradiated wheat mutants. PMID:35139819
Defining the mutation sites in chickpea nodulation mutants PM233 and PM405. PMID:35139814
Sequencing Independent Molecular Typing of Staphylococcus aureus Isolates: Approach for Infection Control and Clonal Characterization. PMID:35138156
The COMBAT-TB Workbench: Making Powerful Mycobacterium tuberculosis Bioinformatics Accessible. PMID:35138128
Genome Sequencing of a Gray Wolf from Peninsular India Provides New Insights into the Evolution and Hybridization of Gray Wolves. PMID:35137061
Respiratory reoxidation of NADH is a key contributor to high oxygen requirements of oxygen-limited cultures of Ogataea parapolymorpha. PMID:35137036
SCHOOL: Software for Clinical Health in Oncology for Omics Laboratories. PMID:35136669
Development and validation of a high throughput SARS-CoV-2 whole genome sequencing workflow in a clinical laboratory. PMID:35136154
Whole-genome resequencing of temporally stratified samples reveals substantial loss of haplotype diversity in the highly inbred Scandinavian wolf population. PMID:35135873
PredicTF: prediction of bacterial transcription factors in complex microbial communities using deep learning. PMID:35135629
An improved ovine reference genome assembly to facilitate in-depth functional annotation of the sheep genome. PMID:35134925
The phylogeny of Salix revealed by whole genome re-sequencing suggests different sex-determination systems in major groups of the genus. PMID:35134824
Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity. PMID:35134344
Detection and Interspecies Comparison of SARS-CoV-2 Delta Variant (AY.3) in Feces from a Domestic Cat and Human Samples. PMID:35132417
A High-Density Genetic Map Enables Genome Synteny and QTL Mapping of Vegetative Growth and Leaf Traits in Gardenia. PMID:35132310
Vertical stratification of the air microbiome in the lower troposphere. PMID:35131944
Single-cell isoform analysis in human immune cells. PMID:35130954
SARS-CoV-2 Variants Associated with Vaccine Breakthrough in the Delaware Valley through Summer 2021. PMID:35130727
Antiviral metabolite 3'-deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19. PMID:35128501
Genome-wide evolutionary response of European oaks during the Anthropocene. PMID:35127134
Comparing genome scans among species of the stickleback order reveals three different patterns of genetic diversity. PMID:35127027
Population genomics of free-ranging Great Plains white-tailed and mule deer reflects a long history of interspecific hybridization. PMID:35126651
Hybridization and range expansion in tamarisk beetles (Diorhabda spp.) introduced to North America for classical biological control. PMID:35126648
Genome-Wide Identification of Loci Associated With Phenology-Related Traits and Their Adaptive Variations in a Highbush Blueberry Collection. PMID:35126419
Improved 93-11 Genome and Time-Course Transcriptome Expand Resources for Rice Genomics. PMID:35126409
Screening and Identification of the First Non-CRISPR/Cas9-Treated Chinese Miniature Pig With Defective Porcine Endogenous Retrovirus pol Genes. PMID:35126361
Sex-Specific Genomic Region Identification and Molecular Sex Marker Development of Rock Bream (Oplegnathus fasciatus). PMID:35122574
NR2F2 controls malignant squamous cell carcinoma state by promoting stemness and invasion and repressing differentiation. PMID:35122061
Radiation therapy enhances immunotherapy response in microsatellite stable colorectal and pancreatic adenocarcinoma in a phase II trial. PMID:35122060
Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma. PMID:35122047
Super enhancers define regulatory subtypes and cell identity in neuroblastoma. PMID:35121888
Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis. PMID:35121877
SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape. PMID:35120605
Recombinant Lloviu virus as a tool to study viral replication and host responses. PMID:35120176
Targeted DamID in C. elegans reveals a direct role for LIN-22 and NHR-25 in antagonizing the epidermal stem cell fate. PMID:35119932
Genomic basis for skin phenotype and cold adaptation in the extinct Steller's sea cow. PMID:35119923
Isolation and whole-genome sequencing of a novel aviadenovirus from owls in Japan. PMID:35118528
Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics. PMID:35118437
Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo. PMID:35118356
Super-enhancers modulate interleukin-6 expression and function in cancers. PMID:35117919
Genome-wide expression changes mediated by A-to-I RNA editing correlate with hepatic oncogenesis. PMID:35116583
Improving the efficiency of single-cell genome sequencing based on overlapping pooling strategy and CNV analysis. PMID:35116153
The landscape of promoter-centred RNA-DNA interactions in rice. PMID:35115727
SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes. PMID:35115713
Establishment of reference standards for multifaceted mosaic variant analysis. PMID:35115554
Graph-based pan-genome reveals structural and sequence variations related to agronomic traits and domestication in cucumber. PMID:35115520
Genomic insights into the evolution of Echinochloa species as weed and orphan crop. PMID:35115514
An investigation into the role of inherited CEACAM gene family variants and colorectal cancer risk. PMID:35115044
An ultra-rare case of immunoskeletal dysplasia with neurodevelopmental abnormalities in an Indian patient with homozygous c.953C > T variant in EXTL3 gene: a case report. PMID:35114981
PΨFinder: a practical tool for the identification and visualization of novel pseudogenes in DNA sequencing data. PMID:35114952
Draft Metagenome-Assembled Genomes from Methane-Rich Echo Lake, Montana. PMID:35112901
Whole-Genome Sequence of Pseudomonas sp. Strain MM211, Isolated from Soil in Langenfeld, Germany. PMID:35112898
The complete chloroplast genome of Nymphaea thermarum (Nymphaeaceae) from Rwanda, Africa. PMID:35111940
Evolution and Stress Responses of CLO Genes and Potential Function of the GhCLO06 Gene in Salt Resistance of Cotton. PMID:35111180
Comparison of GATK and DeepVariant by trio sequencing. PMID:35110657
Manipulation of RNA polymerase III by Herpes Simplex Virus-1. PMID:35110532
An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim. PMID:35109894
SIX1 reprograms myogenic transcription factors to maintain the rhabdomyosarcoma undifferentiated state. PMID:35108532
Computational prediction of intracellular targets of wild-type or mutant vesicular stomatitis matrix protein. PMID:35108303
Deeply conserved synteny and the evolution of metazoan chromosomes. PMID:35108053
Microbial Nitrogen Transformation Potential in Sediments of Two Contrasting Lakes Is Spatially Structured but Seasonally Stable. PMID:35107340
Generating Sequencing-Based DNA Methylation Maps from Low DNA Input Samples. PMID:35103959
Fine-mapping and candidate gene analysis of a major locus controlling leaf thickness in rice (Oryza sativa L.). PMID:35103045
Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition. PMID:35102339
Pathogenomic analyses of Shigella isolates inform factors limiting shigellosis prevention and control across LMICs. PMID:35102306
Particulate hexavalent chromium alters microRNAs in human lung cells that target key carcinogenic pathways. PMID:35101437
Genome-wide run of homozygosity analysis reveals candidate genomic regions associated with environmental adaptations of Tibetan native chickens. PMID:35100979
Elongation factor TFIIS is essential for heat stress adaptation in plants. PMID:35100405
Assembled and annotated 26.5 Gbp coast redwood genome: a resource for estimating evolutionary adaptive potential and investigating hexaploid origin. PMID:35100403
Genomic patterns of transcription-replication interactions in mouse primary B cells. PMID:35100392
Genome-wide insights into adaptive hybridisation across the Schistosoma haematobium group in West and Central Africa. PMID:35100291
Deleterious Mutations Accumulate Faster in Allopolyploid Than Diploid Cotton (Gossypium) and Unequally between Subgenomes. PMID:35099532
A genomic exploration of the early evolution of extant cats and their sabre-toothed relatives [version 2; peer review: 2 approved]. PMID:35098251
Multi-CUT&Tag to simultaneously profile multiple chromatin factors. PMID:35098158
Genetic diversity estimates for the Caenorhabditis Intervention Testing Program screening panel. PMID:35098051
Mycobacterium leprae Transcriptome During In Vivo Growth and Ex Vivo Stationary Phases. PMID:35096659
Genome-Wide and Exome-Capturing Sequencing of a Gamma-Ray-Induced Mutant Reveals Biased Variations in Common Wheat. PMID:35095966
Select and Sequence of a Segregating Sugar Beet Population Provides Genomic Perspective of Host Resistance to Seedling Rhizoctonia solani Infection. PMID:35095959
Targeted Genome Mining Reveals the Psychrophilic Clostridium estertheticum Complex as a Potential Source for Novel Bacteriocins, Including Cesin A and Estercticin A. PMID:35095812
Nosocomial Outbreak of Carbapenemase-Producing Proteus mirabilis With Two Novel Salmonella Genomic Island 1 Variants Carrying Different bla NDM-1 Gene Copies in China. PMID:35095811
Analysis of LINE1 Retrotransposons in Huntington's Disease. PMID:35095420
Unraveling novel and rare mutations for alpha-amylase and key transcription factors in EMS-induced wheat mutants for amylose by TILLING. PMID:35092561
EndoTime: non-categorical timing estimates for luteal endometrium. PMID:35092277
Loss of NFE2L3 protects against inflammation-induced colorectal cancer through modulation of the tumor microenvironment. PMID:35091681
Natural and human-driven selection of a single non-coding body size variant in ancient and modern canids. PMID:35090588
NetSeekR: a network analysis pipeline for RNA-Seq time series data. PMID:35090393
Recursive splicing is a rare event in the mouse brain. PMID:35089962
Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage. PMID:35089911
ggComp enables dissection of germplasm resources and construction of a multiscale germplasm network in wheat. PMID:35088857
Transcriptional and Physiological Analyses to Assess the Effects of a Novel Biostimulant in Tomato. PMID:35087552
The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites. PMID:35087229
Analysis of mRNA-derived siRNAs in mutants of mRNA maturation and surveillance pathways in Arabidopsis thaliana. PMID:35087200
Whole-genome sequencing of Mycobacterium tuberculosis for prediction of drug resistance. PMID:35086603
Sex differences in immune gene expression in the brain of a small shorebird. PMID:35084547
Approximate Bayesian Computation Untangles Signatures of Contemporary and Historical Hybridization between Two Endangered Species. PMID:35084503
Placing Ancient DNA Sequences into Reference Phylogenies. PMID:35084493
Genome diversity of domesticated Acinetobacter baumannii ATCC 19606T strains. PMID:35084299
First identification of two co-existing genome-wide significant sex quantitative trait loci (QTL) in red tilapia using integrative QTL mapping. PMID:35084126
Comprehensive Genomic Discovery of Non-Coding Transcriptional Enhancers in the African Malaria Vector Anopheles coluzzii. PMID:35082832
Regulatory Roles of Small Non-coding RNAs in Sugar Beet Resistance Against Beet curly top virus. PMID:35082811
Petabase-scale sequence alignment catalyses viral discovery. PMID:35082445
Utilizing museomics to trace the complex history and species boundaries in an avian-study system of conservation concern. PMID:35082388
The pollen virome of wild plants and its association with variation in floral traits and land use. PMID:35082293
Citrus Huanglongbing is a pathogen-triggered immune disease that can be mitigated with antioxidants and gibberellin. PMID:35082290
Phage Genes Induce Quorum Sensing Signal Release through Membrane Vesicle Formation. PMID:35082176
scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells. PMID:35081365
SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers. PMID:35081363
Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy. PMID:35080970
Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice. PMID:35080423
Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells. PMID:35078993
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage. PMID:35078986
Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer. PMID:35078920
Genetic basis of a spontaneous mutation's expressivity. PMID:35078232
Distribution, organization and expression of genes concerned with anaerobic lactate utilization in human intestinal bacteria. PMID:35077342
A simple guide to de novo transcriptome assembly and annotation. PMID:35076693
Polycomb Repressive Complex 2 in Eukaryotes-An Evolutionary Perspective. PMID:35076495
Nicotinamide Riboside-Conditioned Microbiota Deflects High-Fat Diet-Induced Weight Gain in Mice. PMID:35076278
Proteomics and Transcriptomics Uncover Key Processes for Elasnin Tolerance in Methicillin-Resistant Staphylococcus aureus. PMID:35076266
Selective signatures and high genome-wide diversity in traditional Brazilian manioc (Manihot esculenta Crantz) varieties. PMID:35075210
Presence of periodontal pathogenic bacteria in blood of patients with coronary artery disease. PMID:35075206
Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant. PMID:35075154
Human reproduction is regulated by retrotransposons derived from ancient Hominidae-specific viral infections. PMID:35075135
Significance of gene variants for the functional biogeography of the near-surface Atlantic Ocean microbiome. PMID:35075131
Mitochondrial DNA variation across 56,434 individuals in gnomAD. PMID:35074858
Integrated 5-hydroxymethylcytosine and fragmentation signatures as enhanced biomarkers in lung cancer. PMID:35073982
Disruption of Active Trans-Sialidase Genes Impairs Egress from Mammalian Host Cells and Generates Highly Attenuated Trypanosoma cruzi Parasites. PMID:35073735
GA4GH: International policies and standards for data sharing across genomic research and healthcare. PMID:35072136
Single-Cell Transcriptomes Combining with Consecutive Genomics Reveal Clonal Evolution and Gene Regulatory Networks in Relapsed and Refractory Multiple Myeloma. PMID:35071234
5-Hydroxymethylcytosine Signatures in Circulating Cell-Free DNA as Early Warning Biomarkers for COVID-19 Progression and Myocardial Injury. PMID:35071229
Evolution of a New Testis-Specific Functional Promoter Within the Highly Conserved Map2k7 Gene of the Mouse. PMID:35069705
Population Evolution, Genetic Diversity and Structure of the Medicinal Legume, Glycyrrhiza uralensis and the Effects of Geographical Distribution on Leaves Nutrient Elements and Photosynthesis. PMID:35069610
Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration. PMID:35069485
Hybrid, ultra-deep metagenomic sequencing enables genomic and functional characterization of low-abundance species in the human gut microbiome. PMID:35067170
Curcumin sensitizes response to cytarabine in acute myeloid leukemia by regulating intestinal microbiota. PMID:35066694
Analysis and Performance Assessment of the Whole Genome Bisulfite Sequencing Data Workflow: Currently Available Tools and a Practical Guide to Advance DNA Methylation Studies. PMID:35064762
Massively parallel characterization of engineered transcript isoforms using direct RNA sequencing. PMID:35064117
Activation of the plant mevalonate pathway by extracellular ATP. PMID:35064110
Neural transcriptomic signature of chronic wasting disease in white-tailed deer. PMID:35062879
Vaccine Breakthrough Infections by SARS-CoV-2 Variants after ChAdOx1 nCoV-19 Vaccination in Healthcare Workers. PMID:35062715
Four Novel Mycoviruses from the Hypovirulent Botrytis cinerea SZ-2-3y Isolate from Paris polyphylla: Molecular Characterisation and Mitoviral Sequence Transboundary Entry into Plants. PMID:35062353
Detection of Low-Copy Human Virus DNA upon Prolonged Formalin Fixation. PMID:35062338
A Population of CD4+CD8+ Double-Positive T Cells Associated with Risk of Plasma Leakage in Dengue Viral Infection. PMID:35062294
A complex network of interactions governs DNA methylation at telomeric regions. PMID:35061900
Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo. PMID:35061532
An evolutionarily conserved mechanism that amplifies the effect of deleterious mutations in osteosarcoma. PMID:35061070
Overexpression of Parkin in clear cell renal cell carcinoma decreases tumor aggressiveness by regulating CKS2 levels. PMID:35059737
m6A-label-seq: A metabolic labeling protocol to detect transcriptome-wide mRNA N 6-methyladenosine (m6A) at base resolution. PMID:35059657
A PtrLBD39-mediated transcriptional network regulates tension wood formation in Populus trichocarpa. PMID:35059630
Correction of a Factor VIII genomic inversion with designer-recombinases. PMID:35058465
No link between population isolation and speciation rate in squamate reptiles. PMID:35058358
Occasional paternal inheritance of the germline-restricted chromosome in songbirds. PMID:35058355
Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content. PMID:35057759
Selective Isolation of Eggerthella lenta from Human Faeces and Characterisation of the Species Prophage Diversity. PMID:35056644
SARS-CoV-2 Evolution and Spike-Specific CD4+ T-Cell Response in Persistent COVID-19 with Severe HIV Immune Suppression. PMID:35056592
Complete Genome Sequence, Molecular Characterization and Phylogenetic Relationships of a Novel Tern Atadenovirus. PMID:35056480
Phenotypic Selection of Dairy Cattle Infected with Bovine Leukemia Virus Demonstrates Immunogenetic Resilience through NGS-Based Genotyping of BoLA MHC Class II Genes. PMID:35056052
Clin.iobio: A Collaborative Diagnostic Workflow to Enable Team-Based Precision Genomics. PMID:35055388
Novel Mutations in GPR68 and SLC24A4 Cause Hypomaturation Amelogenesis Imperfecta. PMID:35055328
The Landscape of Autophagy-Related (ATG) Genes and Functional Characterization of TaVAMP727 to Autophagy in Wheat. PMID:35055085
Exosomal and Plasma Non-Coding RNA Signature Associated with Urinary Albumin Excretion in Hypertension. PMID:35055008
Frequency and Spectrum of Mutations Induced by Gamma Rays Revealed by Phenotype Screening and Whole-Genome Re-Sequencing in Arabidopsis thaliana. PMID:35054839
XRCC4 and MRE11 Roles and Transcriptional Response to Repair of TALEN-Induced Double-Strand DNA Breaks. PMID:35054780
Direct RNA Nanopore Sequencing of SARS-CoV-2 Extracted from Critical Material from Swabs. PMID:35054462
An Interplay between Viruses and Bacteria Associated with the White Sea Sponges Revealed by Metagenomics. PMID:35054418
Revisiting the Non-Coding Nature of Pospiviroids. PMID:35053381
Transcriptomic-Based Quantification of the Epithelial-Hybrid-Mesenchymal Spectrum across Biological Contexts. PMID:35053177
Construction of a High-Density Genetic Linkage Map for the Mapping of QTL Associated with Growth-Related Traits in Sea Cucumber (Apostichopus japonicus). PMID:35053048
Transposable Elements in the Genome of the Lichen-Forming Fungus Umbilicaria pustulata and Their Distribution in Different Climate Zones along Elevation. PMID:35053022
Ancient Mitogenomes Suggest Stable Mitochondrial Clades of the Siberian Roe Deer. PMID:35052455
Rapid Cis-Trans Coevolution Driven by a Novel Gene Retroposed from a Eukaryotic Conserved CCR4-NOT Component in Drosophila. PMID:35052398
Detection of A-to-I RNA Editing in SARS-COV-2. PMID:35052382
Characterization of RNA Editome in the Mammary Gland of Yaks during the Lactation and Dry Periods. PMID:35049829
Archaeal and Bacterial Metagenome-Assembled Genome Sequences Derived from Pig Feces. PMID:35049348
Variational autoencoding of gene landscapes during mouse CNS development uncovers layered roles of Polycomb Repressor Complex 2. PMID:35048973
Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes. PMID:35048970
Genome resequencing-based high-density genetic map and QTL detection for yield and fiber quality traits in diploid Asiatic cotton (Gossypium arboreum). PMID:35048185
Interfamily grafting capacity of petunia. PMID:35048114
High-grade ovarian cancer associated H/ACA snoRNAs promote cancer cell proliferation and survival. PMID:35047824
Distal regulation, silencers, and a shared combinatorial syntax are hallmarks of animal embryogenesis. PMID:35045977
Geometric morphology and population genomics provide insights into the adaptive evolution of Apis cerana in Changbai Mountain. PMID:35045823
Genomic surveillance of SARS-CoV-2 in the state of Delaware reveals tremendous genomic diversity. PMID:35045124
Widespread occurrence of hybrid internal-terminal exons in human transcriptomes. PMID:35044812
Intracellular Transposition and Capture of Mobile Genetic Elements following Intercellular Conjugation of Multidrug Resistance Conjugative Plasmids from Clinical Enterobacteriaceae Isolates. PMID:35044219
TAF4b transcription networks regulating early oocyte differentiation. PMID:35043944
QTL mapping and genomic analyses of earliness and fruit ripening traits in a melon Recombinant Inbred Lines population supported by de novo assembly of their parental genomes. PMID:35043206
Expanding the genetic variation of Brassica juncea by introgression of the Brassica rapa Genome. PMID:35043197
KRAB zinc finger protein ZNF676 controls the transcriptional influence of LTR12-related endogenous retrovirus sequences. PMID:35042549
DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes. PMID:35041655
Finding Maximal Exact Matches Using the r-Index. PMID:35041518
Interaction of Periplasmic Fab Production and Intracellular Redox Balance in Escherichia coli Affects Product Yield. PMID:35041397
Quantitative trait loci mapping for free amino acid content using an albino population and SNP markers provides insight into the genetic improvement of tea plants. PMID:35040977
Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe. PMID:35040778
Genome-wide patterns of genetic diversity, population structure and demographic history in mānuka (Leptospermum scoparium) growing on indigenous Māori land. PMID:35039864
Variation burst during dedifferentiation and increased CHH-type DNA methylation after 30 years of in vitro culture of sweet orange. PMID:35039837
Functional characterization of the tomato HAIRPLUS gene reveals the implication of the epigenome in the control of glandular trichome formation. PMID:35039829
LINE1 are spliced in non-canonical transcript variants to regulate T cell quiescence and exhaustion. PMID:35039641
Genomic interrogation of a MAGIC population highlights genetic factors controlling fiber quality traits in cotton. PMID:35039628
The SF3B1R625H mutation promotes prolactinoma tumor progression through aberrant splicing of DLG1. PMID:35039052
The Genetic Origin of Daunians and the Pan-Mediterranean Southern Italian Iron Age Context. PMID:35038748
Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors. PMID:35038579
Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium. PMID:35037357
RiboReport - benchmarking tools for ribosome profiling-based identification of open reading frames in bacteria. PMID:35037022
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function. PMID:35036997
Telomerase Reverse Transcriptase Preserves Neuron Survival and Cognition in Alzheimer's Disease Models. PMID:35036927
Transposable element activation promotes neurodegeneration in a Drosophila model of Huntington's disease. PMID:35036881
An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs. PMID:35036870
Chromatin Immunoprecipitation dataset of H3ac and H3K27me3 histone marks followed by DNA sequencing of Medicago truncatula embryos during control and heat stress conditions to decipher epigenetic regulation of desiccation tolerance acquisition. PMID:35036490
Whole-Genome Sequencing Revealed a Late-Maturing Isogenic Rice Koshihikari Integrated with Hd16 Gene Derived from an Ise Shrine Mutant. PMID:35036423
Slinker: Visualising novel splicing events in RNA-Seq data. PMID:35035899
Epigenomic signatures on paralogous genes reveal underappreciated universality of active histone codes adopted across animals. PMID:35035788
SNP-Based Genetic Linkage Map and Quantitative Trait Locus Mapping Associated with the Agronomically Important Traits of Hypsizygus marmoreus. PMID:35035250
Identification of QTLs for stagnant flooding tolerance in rice employing genotyping by sequencing of a RIL population derived from Swarna × Rashpanjor. PMID:35035143
Development and application of KASP markers associated with Restorer-of-fertility gene in Capsicum annuum L. PMID:35035134
Mapping short tandem repeats for liver gene expression traits helps prioritize potential causal variants for complex traits in pigs. PMID:35034641
Genetic isolation by distance underlies colour pattern divergence in red-eyed treefrogs (Agalychnis callidryas). PMID:35034406
Spatial and temporal distribution of SARS-CoV-2 diversity circulating in wastewater. PMID:35033744
Genomic perspectives on the emerging SARS-CoV-2 omicron variant. PMID:35033679
Cold case: The disappearance of Egypt bee virus, a fourth distinct master strain of deformed wing virus linked to honeybee mortality in 1970's Egypt. PMID:35033134
Core promoter mutation contributes to abnormal gene expression in bladder cancer. PMID:35033028
Association of ultra-rare coding variants with genetic generalized epilepsy: A case-control whole exome sequencing study. PMID:35032048
Genome sequencing and population resequencing provide insights into the genetic basis of domestication and diversity of vegetable soybean. PMID:35031802
A chromosome-scale genome assembly for the holly (Ilex polyneura) provides insights into genomic adaptations to elevation in Southwest China. PMID:35031793
Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. PMID:35031607
ECCsplorer: a pipeline to detect extrachromosomal circular DNA (eccDNA) from next-generation sequencing data. PMID:35030991
The genetic identity of the earliest human-made hybrid animals, the kungas of Syro-Mesopotamia. PMID:35030024
Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint. PMID:35028974
CUT&Tag-BS for simultaneous profiling of histone modification and DNA methylation with high efficiency and low cost. PMID:35028637
Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight. PMID:35028613
The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ. PMID:35027560
The role of ATXR6 expression in modulating genome stability and transposable element repression in Arabidopsis. PMID:35027454
Sulfate-dependant microbially induced corrosion of mild steel in the deep sea: a 10-year microbiome study. PMID:35027090
High-Quality Reference Genome for an Arid-Adapted Mammal, the Banner-Tailed Kangaroo Rat (Dipodomys spectabilis). PMID:35026029
Case series of congenital pseudarthrosis of the tibia unfulfilling neurofibromatosis type 1 diagnosis: 21% with somatic NF1 haploinsufficiency in the periosteum. PMID:35024939
ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology. PMID:35023830
Demographic History and Natural Selection Shape Patterns of Deleterious Mutation Load and Barriers to Introgression across Populus Genome. PMID:35022759
Halvade somatic: Somatic variant calling with Apache Spark. PMID:35022699
System analysis of the sequencing quality of human whole exome samples on BGI NGS platform. PMID:35022470
The formation of avian montane diversity across barriers and along elevational gradients. PMID:35022441
De novo mutations identified by whole-genome sequencing implicate chromatin modifications in obsessive-compulsive disorder. PMID:35020433
Comparative Study of Ten Thogotovirus Isolates and Their Distinct In Vivo Characteristics. PMID:35019718
Characterization of a 2016-2017 Human Seasonal H3 Influenza A Virus Spillover Now Endemic to U.S. Swine. PMID:35019669
Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing. PMID:35019138
Identification and characterisation of SARS-CoV-2 and Human alphaherpesvirus 1 from a productive coinfection in a fatal COVID-19 case. PMID:35019069
The Mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates. PMID:35018888
Molecular and morphological analyses clarify species delimitation in section Costatae and reveal Betula buggsii sp. nov. (sect. Costatae, Betulaceae) in China. PMID:35018419
Advanced genomics identifies growth effectors for proteotoxic ER stress recovery in Arabidopsis thaliana. PMID:35017639
MyoD is a 3D genome structure organizer for muscle cell identity. PMID:35017543
Different phases of aging in mouse old skeletal muscle. PMID:35017317
Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance. PMID:35017298
Evidence of SARS-CoV-2 symptomatic reinfection in four healthcare professionals from the same hospital despite the presence of antibodies. PMID:35017107
Hackflex: low-cost, high-throughput, Illumina Nextera Flex library construction. PMID:35014949
Evolutionary Ecology of Natural Comammox Nitrospira Populations. PMID:35014874
Protein disulfide isomerase A1‑associated pathways in the development of stratified breast cancer therapies. PMID:35014681
An ancient positively selected BMPRIB missense variant increases litter size of Mongolian sheep populations following latitudinal gradient. PMID:35013854
KAS-seq: genome-wide sequencing of single-stranded DNA by N3-kethoxal-assisted labeling. PMID:35013616
Alternative polyadenylation by sequential activation of distal and proximal PolyA sites. PMID:35013598
Tissue specific expression of UMAMIT amino acid transporters in wheat. PMID:35013480
The insertion and dysregulation of transposable elements in osteosarcoma and their association with patient event-free survival. PMID:35013466
Towards a metagenomics machine learning interpretable model for understanding the transition from adenoma to colorectal cancer. PMID:35013454
Protein interaction networks define the genetic architecture of preterm birth. PMID:35013336
The m6A methyltransferase METTL3 regulates muscle maintenance and growth in mice. PMID:35013323
Phylogenetically and functionally diverse microorganisms reside under the Ross Ice Shelf. PMID:35013291
Single-cell chromatin accessibility landscape in kidney identifies additional cell-of-origin in heterogenous papillary renal cell carcinoma. PMID:35013217
A de novo paradigm for male infertility. PMID:35013161
Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer. PMID:35012638
Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast. PMID:35012333
Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B. PMID:35011680
Enhancer RNA Expression in Response to Glucocorticoid Treatment in Murine Macrophages. PMID:35011590
Comparative Transcriptomic Analysis Reveals Diverse Expression Pattern Underlying Fatty Acid Composition among Different Beef Cuts. PMID:35010243
Nucleotide Sequence Variation in Long-Term Tissue Cultures of Chinese Ginseng (Panax ginseng C. A. Mey.). PMID:35009083
Reassessment of Annamocarya sinesis (Carya sinensis) Taxonomy through Concatenation and Coalescence Phylogenetic Analysis. PMID:35009055
Genome-Wide Variation Analysis of Four Vegetable Soybean Cultivars Based on Re-Sequencing. PMID:35009032
Whole-Genome Resequencing of Near-Isogenic Lines Reveals a Genomic Region Associated with High Trans-Lycopene Contents in Watermelon. PMID:35009012
Searching for a Needle in a Haystack: Cas9-Targeted Nanopore Sequencing and DNA Methylation Profiling of Full-Length Glutenin Genes in a Big Cereal Genome. PMID:35009008
CTCF Expression and Dynamic Motif Accessibility Modulates Epithelial-Mesenchymal Gene Expression. PMID:35008373
Whole-Exome Sequencing of HPV Positive Tonsillar and Base of Tongue Squamous Cell Carcinomas Reveals a Global Mutational Pattern along with Relapse-Specific Somatic Variants. PMID:35008243
RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers. PMID:35006434
Two genomic regions of a sodium azide induced rice mutant confer broad-spectrum and durable resistance to blast disease. PMID:35006368
Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.). PMID:35006334
Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria. PMID:35006075
Mapping atypical UV photoproducts in vitro and across the S. cerevisiae genome. PMID:35005641
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson's disease myeloid cells. PMID:35005630
KNNCNV: A K-Nearest Neighbor Based Method for Detection of Copy Number Variations Using NGS Data. PMID:35004691
SARS-CoV-2 causes a significant stress response mediated by small RNAs in the blood of COVID-19 patients. PMID:35003892
Demographic history and genetic diversity of wild African harlequin quail (Coturnix delegorguei delegorguei) populations of Kenya. PMID:35003693
Low base-substitution mutation rate and predominance of insertion-deletion events in the acidophilic bacterium Acidobacterium capsulatum. PMID:35003627
Harnessing Genetic Diversity in the USDA Pea Germplasm Collection Through Genomic Prediction. PMID:35003202
CRAM 3.1: Advances in the CRAM File Format. PMID:34999766
Chicken blastoderms and primordial germ cells possess a higher expression of DNA repair genes and lower expression of apoptosis genes to preserve their genome stability. PMID:34997179
BIRC2-BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia. PMID:34997070
Insights into opium poppy (Papaver spp.) genetic diversity from genotyping-by-sequencing analysis. PMID:34997061
Recruitment of an ancient branching program to suppress carpel development in maize flowers. PMID:34996873
Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors. PMID:34995493
Anatomy promotes neutral coexistence of strains in the human skin microbiome. PMID:34995483
Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation. PMID:34995116
The complete mitochondrial genome of Uroleucon erigeronense (Thomas, 1878) (Hemiptera: Aphididae). PMID:34993319
Mutation of Hashimoto's Thyroiditis and Papillary Thyroid Carcinoma Related Genes and the Screening of Candidate Genes. PMID:34993154
Whole Genome Methylation Analysis Reveals Role of DNA Methylation in Cow's Ileal and Ileal Lymph Node Responses to Mycobacterium avium subsp. paratuberculosis Infection. PMID:34992636
Unravelling Rubber Tree Growth by Integrating GWAS and Biological Network-Based Approaches. PMID:34992619
ASMdb: a comprehensive database for allele-specific DNA methylation in diverse organisms. PMID:34664666
Diurnal RNAPII-tethered chromatin interactions are associated with rhythmic gene expression in rice. PMID:34991658
Uncovering Differentially Methylated Regions (DMRs) in a Salt-Tolerant Rice Variety under Stress: One Step towards New Regulatory Regions for Enhanced Salt Tolerance. PMID:34991273
YAP1 and PRDM14 converge to promote cell survival and tumorigenesis. PMID:34990589
Whole-Genome Sequencing of Streptomycin-Resistant Mycobacterium tuberculosis Strain SBH145 from Sabah, Malaysia. PMID:34989616
FIONA1-Mediated m6 A Modification Regulates the Floral Transition in Arabidopsis. PMID:34989479
Unique structure and positive selection promote the rapid divergence of Drosophila Y chromosomes. PMID:34989337
Revisiting proboscidean phylogeny and evolution through total evidence and palaeogenetic analyses including Notiomastodon ancient DNA. PMID:34988402
Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models. PMID:34988393
Saline lakes on the Qinghai-Tibet Plateau harbor unique viral assemblages mediating microbial environmental adaption. PMID:34988389
Ancient DNA diffuses from human bones to cave stones. PMID:34988387
Comparative Genome and Transcriptome Integration Studies Reveal the Mechanism of Pectoral Muscle Development and Function in Pigeons. PMID:34987544
Decoding gene regulation in the fly brain. PMID:34987221
Inferring the distribution of fitness effects in patient-sampled and experimental virus populations: two case studies. PMID:34987185
Caenorhabditis elegans ETR-1/CELF has broad effects on the muscle cell transcriptome, including genes that regulate translation and neuroblast migration. PMID:34986795
DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells. PMID:34986190
Detection of MDM2 amplification by shallow whole genome sequencing of cell-free DNA of patients with dedifferentiated liposarcoma. PMID:34986184
Second Messenger c-di-GMP Modulates Exopolysaccharide Pea-Dependent Phenotypes via Regulation of eppA Expression in Pseudomonas putida. PMID:34985979
Blood transcriptome analysis revealed the immune changes and immunological adaptation of wildness training giant pandas. PMID:34985592
Inferring the genetic responses to acute drought stress across an ecological gradient. PMID:34983380
Two-step fitness selection for intra-host variations in SARS-CoV-2. PMID:34982968
Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos. PMID:34982026
Integrative analysis of the 3D genome structure reveals that CTCF maintains the properties of mouse female germline stem cells. PMID:34981210
Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars. PMID:34980919
Intermittent compressive force induces cell cycling and reduces apoptosis in embryoid bodies of mouse induced pluripotent stem cells. PMID:34980892
CRISPR guides induce gene silencing in plants in the absence of Cas. PMID:34980227
Assessing reproducibility of inherited variants detected with short-read whole genome sequencing. PMID:34980216
On-treatment blood TMB as predictors for camrelizumab plus chemotherapy in advanced lung squamous cell carcinoma: biomarker analysis of a phase III trial. PMID:34980131
Mapping of dwarfing QTL of Ari1327, a semi-dwarf mutant of upland cotton. PMID:34979924
Kampo formulas alleviate aging-related emotional disturbances and neuroinflammation in male senescence-accelerated mouse prone 8 mice. PMID:34979499
Diverse myopathological features in the congenital myasthenia syndrome with GFPT1 mutation. PMID:34978387
SARS-CoV-2 in hospital air as revealed by comprehensive respiratory viral panel sequencing. PMID:34977533
Lack of evolutionary changes identified in SARS-CoV-2 for the re-emerging outbreak of COVID-19 in Beijing, China. PMID:34977529
Comparative Enhancer Map of Cattle Muscle Genome Annotated by ATAC-Seq. PMID:34977215
Draft Genome Sequence of a New Fusarium Isolate Belonging to Fusarium tricinctum Species Complex Collected From Hazelnut in Central Italy. PMID:34975974
Profiling of H3K4me3 and H3K27me3 and Their Roles in Gene Subfunctionalization in Allotetraploid Cotton. PMID:34975944
Establishing the Molecular Diagnoses in a Cohort of 291 Patients With Predominantly Antibody Deficiency by Targeted Next-Generation Sequencing: Experience From a Monocentric Study. PMID:34975878
Common Genomic Aberrations in Mouse and Human Breast Cancers with Concurrent P53 Deficiency and Activated PTEN-PI3K-AKT Pathway. PMID:34975329
Transcriptome Dynamics of Human Neuronal Differentiation From iPSC. PMID:34970540
Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans. PMID:34969986
A catalogue of 1,167 genomes from the human gut archaeome. PMID:34969981
Exploring bycatch diversity of organisms in whole genome sequencing of Erebidae moths (Lepidoptera). PMID:34969947
Genetic screen for suppression of transcriptional interference reveals fission yeast 14-3-3 protein Rad24 as an antagonist of precocious Pol2 transcription termination. PMID:34967420
ITGB5 mutation discovered in a Chinese family with blepharophimosis-ptosis-epicanthus inversus syndrome. PMID:34966851
IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution. PMID:34966754
Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis. PMID:34966403
Antibody-free profiling of transcription factor occupancy during early embryogenesis by FitCUT&RUN. PMID:34965941
Epigenetic features improve TALE target prediction. PMID:34965853
ChIP-AP: an integrated analysis pipeline for unbiased ChIP-seq analysis. PMID:34965583
MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells. PMID:34965434
The first comprehensive database of germline pathogenic variants in East Asian cancer patients. PMID:34964846
Low-frequency somatic copy number alterations in normal human lymphocytes revealed by large-scale single-cell whole-genome profiling. PMID:34963662
Ancient Human Genomes and Environmental DNA from the Cement Attaching 2,000-Year-Old Head Lice Nits. PMID:34963129
SARS-CoV-2 variant detection with ADSSpike. PMID:34963097
Genetic diversity of Leptospira isolates in Lao PDR and genome analysis of an outbreak strain. PMID:34962921
Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regions. PMID:34961893
Down-regulation of OsMYB103L distinctively alters beta-1,4-glucan polymerization and cellulose microfibers assembly for enhanced biomass enzymatic saccharification in rice. PMID:34961560
Cold Acclimation in Brachypodium Is Accompanied by Changes in Above-Ground Bacterial and Fungal Communities. PMID:34961295
Reference-Guided De Novo Genome Assembly to Dissect a QTL Region for Submergence Tolerance Derived from Ciherang-Sub1. PMID:34961210
A Novel Pear Scab (Venturia nashicola) Resistance Gene, Rvn3, from Interspecific Hybrid Pear (Pyrus pyrifolia × P. communis). PMID:34961103
Population Variability Generated during Rescue Process and Passaging of Recombinant Mumps Viruses. PMID:34960819
Genomic Epidemiology of Salmonid Alphavirus in Norwegian Aquaculture Reveals Recent Subtype-2 Transmission Dynamics and Novel Subtype-3 Lineages. PMID:34960818
LABRADOR-A Computational Workflow for Virus Detection in High-Throughput Sequencing Data. PMID:34960810
Influence of Ribavirin on Mumps Virus Population Diversity. PMID:34960805
Quasispecies Composition of Small Ruminant Lentiviruses Found in Blood Leukocytes and Milk Epithelial Cells. PMID:34960767
A Novel Terrestrial Rabies Virus Lineage Occurring in South America: Origin, Diversification, and Evidence of Contact between Wild and Domestic Cycles. PMID:34960753
Metatranscriptomic Sequencing Suggests the Presence of Novel RNA Viruses in Rice Transmitted by Brown Planthopper. PMID:34960733
Comparative Genomics of Clinical and Environmental Isolates of Vibrio spp. of Colombia: Implications of Traits Associated with Virulence and Resistance. PMID:34959560
Immunological and Genetic Investigation of SARS-CoV-2 Reinfection in an Otherwise Healthy, Young Marine Recruit. PMID:34959544
Prediction of the Sex-Associated Genomic Region in Tunas (Thunnus Fishes). PMID:34957293
p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms. PMID:34956360
A Chromosome-Level Genome Assembly of Mozambique Tilapia (Oreochromis mossambicus) Reveals the Structure of Sex Determining Regions. PMID:34956335
Novel QTL and Meta-QTL Mapping for Major Quality Traits in Soybean. PMID:34956271
Chromosome-Level Genome Assembly and HazelOmics Database Construction Provides Insights Into Unsaturated Fatty Acid Synthesis and Cold Resistance in Hazelnut (Corylus heterophylla). PMID:34956265
Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro. PMID:34954911
Arabidopsis CHROMATIN REMODELING 19 acts as a transcriptional repressor and contributes to plant pathogen resistance. PMID:34954802
Linking genetic, morphological, and behavioural divergence between inland island and mainland deer mice. PMID:34952930
IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation. PMID:34952640
cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries. PMID:34952565
Genomic analyses of the metastasis-derived prostate cancer cell lines LNCaP, VCaP, and PC3-AR. PMID:34951700
H2A mono-ubiquitination differentiates FACT's functions in nucleosome assembly and disassembly. PMID:34951461
Purification of astrocyte subtype based on a double reporter mice approach for downstream transcription profiling. PMID:34950888
Generation of RNA sequencing libraries for transcriptome analysis of globin-rich tissues of the domestic dog. PMID:34950881
Isolation and Molecular Characteristics of a Novel Recombinant Avian Orthoreovirus From Chickens in China. PMID:34950724
Early queen joining and long-term queen associations in polygyne colonies of an invasive wasp revealed by longitudinal genetic analysis. PMID:34950236
Genomic and common garden approaches yield complementary results for quantifying environmental drivers of local adaptation in rubber rabbitbrush, a foundational Great Basin shrub. PMID:34950235
Genome-wide analysis reveals the genetic stock structure of hoki (Macruronus novaezelandiae). PMID:34950233
Complex introgression among three diverged largemouth bass lineages. PMID:34950231
A masculinizing supergene underlies an exaggerated male reproductive morph in a spider. PMID:34949821
Prochlorococcus have low global mutation rate and small effective population size. PMID:34949817
Resetting of the 24-nt siRNA landscape in rice zygotes. PMID:34949668
Gene by environment interaction mouse model reveals a functional role for 5-hydroxymethylcytosine in neurodevelopmental disorders. PMID:34949667
High Frequency of Juxtamembrane Domain ERBB2 Mutation in Gastric Cancer. PMID:34949663
Gene Amplification as a Mechanism of Yeast Adaptation to Nonsense Mutations in Release Factor Genes. PMID:34946968
Assembly of the Complete Mitochondrial Genome of Chinese Plum (Prunus salicina): Characterization of Genome Recombination and RNA Editing Sites. PMID:34946920
Exploration of Alternative Splicing (AS) Events in MDV-Infected Chicken Spleens. PMID:34946806
Identification of an Exopolysaccharide Biosynthesis Gene in Bradyrhizobium diazoefficiens USDA110. PMID:34946092
Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry. PMID:34944967
A Comparison of Tools for Copy-Number Variation Detection in Germline Whole Exome and Whole Genome Sequencing Data. PMID:34944901
Locus-Specific Methylation of GSTP1, RNF219, and KIAA1539 Genes with Single Molecule Resolution in Cell-Free DNA from Healthy Donors and Prostate Tumor Patients: Application in Diagnostics. PMID:34944854
HSP90 Inhibition Synergizes with Cisplatin to Eliminate Basal-like Pancreatic Ductal Adenocarcinoma Cells. PMID:34944784
Deepening into Intracellular Signaling Landscape through Integrative Spatial Proteomics and Transcriptomics in a Lymphoma Model. PMID:34944421
Pan-Resistome Characterization of Uropathogenic Escherichia coli and Klebsiella pneumoniae Strains Circulating in Uganda and Kenya, Isolated from 2017-2018. PMID:34943759
Genomic Analysis of 18th-Century Kazakh Individuals and Their Oral Microbiome. PMID:34943238
Chromatin accessibility and microRNA expression in nephron progenitor cells during kidney development. PMID:34942352
Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity. PMID:34942120
Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PMID:34941903
Hepatic transcriptome analysis identifies genes, polymorphisms and pathways involved in the fatty acids metabolism in sheep. PMID:34941886
Integration of whole genome sequencing and transcriptomics reveals a complex picture of the reestablishment of insecticide resistance in the major malaria vector Anopheles coluzzii. PMID:34941884
Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis. PMID:34941867
Cell-by-cell dissection of phloem development links a maturation gradient to cell specialization. PMID:34941412
Genetic Connections and Convergent Evolution of Tropical Indigenous Peoples in Asia. PMID:34940850
An Evolutionary Perspective on Hox Binding Site Preferences in Two Different Tissues. PMID:34940504
Genomic Traces of the Fruit Fly Anastrepha obliqua Associated with Its Polyphagous Nature. PMID:34940204
A New Mitochondrial Genome of Sogatella furcifera (Horváth) (Hemiptera: Delphacidae) and Mitogenome-Wide Investigation on Polymorphisms. PMID:34940154
Mechanisms underlying Clostridium pasteurianum's metabolic shift when grown with Geobacter sulfurreducens. PMID:34939136
Valine tRNA levels and availability regulate complex I assembly in leukaemia. PMID:34937946
Non-syntrophic methanogenic hydrocarbon degradation by an archaeal species. PMID:34937940
Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar. PMID:34936652
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion. PMID:34935874
A nationwide genomic study of clinical Klebsiella pneumoniae in Norway 2001-15: introduction and spread of ESBLs facilitated by clonal groups CG15 and CG307. PMID:34935048
Recurrent Superenhancer of the Oncogene POU5F1B in Colorectal Cancers. PMID:34934770
Whole Genome Sequencing of First Janibacter indicus Isolate in China Revealed Three Unique Genomic Islands Compared with Saprophytic Strains. PMID:34934330
AnchorWave: Sensitive alignment of genomes with high sequence diversity, extensive structural polymorphism, and whole-genome duplication. PMID:34934012
Identification of starch candidate genes using SLAF-seq and BSA strategies and development of related SNP-CAPS markers in tetraploid potato. PMID:34932571
Characterization of 2 Klebsiella pneumoniae carbapenemase-producing Enterobacterales isolated from canine rectal swabs. PMID:34931554
Innate, translation-dependent silencing of an invasive transposon in Arabidopsis. PMID:34931432
CTCF-mediated chromatin looping provides a topological framework for the formation of phase-separated transcriptional condensates. PMID:34931241
Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury. PMID:34931022
Comprehensive multiomic characterization of human papillomavirus-driven recurrent respiratory papillomatosis reveals distinct molecular subtypes. PMID:34931021
Transcriptomic profiling and pathway analysis of cultured human lung microvascular endothelial cells following ionizing radiation exposure. PMID:34930946
Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids. PMID:34930826
Evolutionary footprints of a cold relic in a rapidly warming world. PMID:34930524
Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts. PMID:34930313
High natural PHA production from acetate in Cobetia sp. MC34 and Cobetia marina DSM 4741T and in silico analyses of the genus specific PhaC2 polymerase variant. PMID:34930259
Intellectual disability genomics: current state, pitfalls and future challenges. PMID:34930158
Whole-Genome Analysis-Based Phylogeographic Investigation of Streptococcus pneumoniae Serotype 19A Sequence Type 320 Isolates in Japan. PMID:34930035
Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant. PMID:34929737
G-Quadruplex DNA as a Target in Pathogenic Bacteria: Efficacy of an Extended Naphthalene Diimide Ligand and Its Mode of Action. PMID:34928608
cLoops2: a full-stack comprehensive analytical tool for chromatin interactions. PMID:34928392
Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress. PMID:34928385
A high-quality genome and comparison of short- versus long-read transcriptome of the palaearctic duck Aythya fuligula (tufted duck). PMID:34927191
Transcriptome-Wide Analyses Identify Dominant as the Predominantly Non-Conservative Alternative Splicing Inheritance Patterns in F1 Chickens. PMID:34925458
Genetic Variation and the Distribution of Variant Types in the Horse. PMID:34925451
Genomic Uniqueness of Local Sheep Breeds From Morocco. PMID:34925440
Arabidopsi s Spliceosome Factor SmD3 Modulates Immunity to Pseudomonas syringae Infection. PMID:34925413
Unstable Relationship Between Braarudosphaera bigelowii (= Chrysochromulina parkeae) and Its Nitrogen-Fixing Endosymbiont. PMID:34925404
Survival Comes at a Cost: A Coevolution of Phage and Its Host Leads to Phage Resistance and Antibiotic Sensitivity of Pseudomonas aeruginosa Multidrug Resistant Strains. PMID:34925289
Alone Yet Not Alone: Frankia Lives Under the Same Roof With Other Bacteria in Actinorhizal Nodules. PMID:34925263
Genome-wide SNP discovery, linkage mapping, and analysis of QTL for morpho-physiological traits in rice during vegetative stage under drought stress. PMID:34924715
Assessing Bos taurus introgression in the UOA Bos indicus assembly. PMID:34922445
Prioritising positively selected variants in whole-genome sequencing data using FineMAV. PMID:34922440
Patterns of piRNA Regulation in Drosophila Revealed through Transposable Element Clade Inference. PMID:34921315
Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids. PMID:34921240
Genomic stability of mouse spermatogonial stem cells in vitro. PMID:34921203
Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift. PMID:34920711
Ancient Demographics Determine the Effectiveness of Genetic Purging in Endangered Lizards. PMID:34919713
Genomic Signatures of a Major Adaptive Event in the Pathogenic Fungus Melampsora larici-populina. PMID:34919678
The pink salmon genome: Uncovering the genomic consequences of a two-year life cycle. PMID:34919547
Accuracy of an amplicon-sequencing nanopore approach to identify variants in tuberculosis drug-resistance-associated genes. PMID:34919513
5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function. PMID:34919053
Integrated multiple transcriptomes in oviductal tissue across the porcine estrous cycle reveal functional roles in oocyte maturation and transport. PMID:34918099
Abundance of Lipopolysaccharide Heptosyltransferase I in Human Gut Microbiome and Its Association With Cardiovascular Disease and Liver Cirrhosis. PMID:34917047
Genomic landscape of a relict fir-associated fungus reveals rapid convergent adaptation towards endophytism. PMID:34916613
An RNA-cleaving threose nucleic acid enzyme capable of single point mutation discrimination. PMID:34916596
The long non-coding RNA landscape of Candida yeast pathogens. PMID:34916523
QTL mapping of a Brazilian bioethanol strain links the cell wall protein-encoding gene GAS1 to low pH tolerance in S. cerevisiae. PMID:34915919
Mining massive genomic data of two Swiss Braunvieh cattle populations reveals six novel candidate variants that impair reproductive success. PMID:34915862
The Dawn of next generation DNA sequencing in myelodysplastic syndromes- experience from Pakistan. PMID:34915860
Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. PMID:34914716
A virus-derived microRNA targets immune response genes during SARS-CoV-2 infection. PMID:34914162
Molecular Characterization and Clinical Relevance of ANXA1 in Gliomas via 1,018 Chinese Cohort Patients. PMID:34912807
MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples. PMID:34912045
Cadmium exposure modulates the gut-liver axis in an Alzheimer's disease mouse model. PMID:34912029
Genomic signatures of pre-resistance in Mycobacterium tuberculosis. PMID:34911948
A high-continuity and annotated tomato reference genome. PMID:34911432
Comparison of Whole-Genome Sequence-Based Methods and PCR Ribotyping for Subtyping of Clostridioides difficile. PMID:34911367
Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation. PMID:34910919
Genomic prediction using low-coverage portable Nanopore sequencing. PMID:34910782
Transcriptional Pathology Evolves over Time in Rat Hippocampus after Lateral Fluid Percussion Traumatic Brain Injury. PMID:34909768
Chromosomal Fusions Facilitate Adaptation to Divergent Environments in Threespine Stickleback. PMID:34908155
BACH2 inhibition reverses β cell failure in type 2 diabetes models. PMID:34907913
Cryptosporidium felis differs from other Cryptosporidium spp. in codon usage. PMID:34907893
An infant burial from Arma Veirana in northwestern Italy provides insights into funerary practices and female personhood in early Mesolithic Europe. PMID:34907203
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia. PMID:34907175
Social stratification without genetic differentiation at the site of Kulubnarti in Christian Period Nubia. PMID:34907168
Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis. PMID:34907080
Nanopore sequencing of RNA and cDNA molecules in Escherichia coli. PMID:34906997
A single-nucleotide mutation within the TBX3 enhancer increased body size in Chinese horses. PMID:34906355
The evolutionary history of Shigella flexneri serotype 6 in Asia. PMID:34904947
Secondary metabolite biosynthetic diversity in Arctic Ocean metagenomes. PMID:34904945
Genomic insights into the circulation of pandemic fluoroquinolone-resistant extra-intestinal pathogenic Escherichia coli ST1193 in Vietnam. PMID:34904942
Introduction and adaptation of an emerging pathogen to olive trees in Italy. PMID:34904938
Taxon-Specific Shifts in Bacterial and Archaeal Transcription of Dissolved Organic Matter Cycling Genes in a Stratified Fjord. PMID:34904860
Lack of transcriptional coordination between mitochondrial and nuclear oxidative phosphorylation genes in the presence of two divergent mitochondrial genomes. PMID:34904419
Intercellular interactions between mast cells and stromal fibroblasts obtained from canine cutaneous mast cell tumours. PMID:34903806
DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease. PMID:34903641
Bacterial microcompartments for isethionate desulfonation in the taurine-degrading human-gut bacterium Bilophila wadsworthia. PMID:34903181
CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature. PMID:34902786
Intratumor heterogeneity and clonal evolution revealed in castration-resistant prostate cancer by longitudinal genomic analysis. PMID:34902740
Detection of N6-methyladenosine in SARS-CoV-2 RNA by methylated RNA immunoprecipitation sequencing. PMID:34901888
Chromatin Accessibility Predetermines Odontoblast Terminal Differentiation. PMID:34901015
Derivedness Index for Estimating Degree of Phenotypic Evolution of Embryos: A Study of Comparative Transcriptomic Analyses of Chordates and Echinoderms. PMID:34900995
Evaluating whole-genome sequencing quality metrics for enteric pathogen outbreaks. PMID:34900416
Ribo-Seq and RNA-Seq of TMA46 ( DFRP1) and GIR2 ( DFRP2) knockout yeast strains. PMID:34900236
A Comparative Analysis of Super-Enhancers and Broad H3K4me3 Domains in Pig, Human, and Mouse Tissues. PMID:34899824
Revealing the Genetic Components Responsible for the Unique Photosynthetic Stem Capability of the Wild Almond Prunus arabica (Olivier) Meikle. PMID:34899807
Suppression and Activation of Intracellular Immune Response in Initial Severe Acute Respiratory Syndrome Coronavirus 2 Infection. PMID:34899651
Limitations of lymphoblastoid cell lines for establishing genetic reference datasets in the immunoglobulin loci. PMID:34898642
Genetic differentiation of Xylella fastidiosa following the introduction into Taiwan. PMID:34898423
Adaptation and Cryptic Pseudogenization in Penguin Toll-Like Receptors. PMID:34897511
Diverse mating phenotypes impact the spread of wtf meiotic drivers in Schizosaccharomyces pombe. PMID:34895466
One-pot universal NicE-seq: all enzymatic downstream processing of 4% formaldehyde crosslinked cells for chromatin accessibility genomics. PMID:34895293
Interaction between Rag genes results in a unique synergistic transcriptional response that enhances soybean resistance to soybean aphids. PMID:34895143
Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency. PMID:34893946
Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells. PMID:34893889
Unique properties of spacer acquisition by the type III-A CRISPR-Cas system. PMID:34893878
Island Biogeography Revisited: Museomics Reveals Affinities of Shelf Island Birds Determined by Bathymetry and Paleo-Rivers, Not by Distance to Mainland. PMID:34893875
High throughput single-cell genome sequencing gives insights into the generation and evolution of mosaic aneuploidy in Leishmania donovani. PMID:34893872
Grouped-seq for integrated phenotypic and transcriptomic screening of patient-derived tumor organoids. PMID:34893868
KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma. PMID:34893606
RNA modifications detection by comparative Nanopore direct RNA sequencing. PMID:34893601
MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome". PMID:34890565
MLL4 mediates differentiation and tumor suppression through ferroptosis. PMID:34890228
Cluster-specific gene markers enhance Shigella and enteroinvasive Escherichia coli in silico serotyping. PMID:34889728
Studies on Growth Characteristics and Cross-Neutralization of Wild-Type and Delta SARS-CoV-2 From Hisar (India). PMID:34888260
QTL Analysis of Five Silique-Related Traits in Brassica napus L. Across Multiple Environments. PMID:34887891
First Sprayable Double-Stranded RNA-Based Biopesticide Product Targets Proteasome Subunit Beta Type-5 in Colorado Potato Beetle (Leptinotarsa decemlineata). PMID:34887882
Decoupling of degradation from deadenylation reshapes poly(A) tail length in yeast meiosis. PMID:34887567
Cell-type-specific chromatin occupancy by the pioneer factor Zelda drives key developmental transitions in Drosophila. PMID:34887421
Differential Transcriptional Reprogramming by Wild Type and Lymphoma-Associated Mutant MYC Proteins as B-Cells Convert to a Lymphoma Phenotype. PMID:34885204
Metagenomic shotgun sequencing reveals host species as an important driver of virome composition in mosquitoes. PMID:33875673
The HROC-Xenobank-A High Quality Assured PDX Biobank of >100 Individual Colorectal Cancer Models. PMID:34884989
An archaeal histone-like protein regulates gene expression in response to salt stress. PMID:34883507
Library-based analysis reveals segment and length dependent characteristics of defective influenza genomes. PMID:34882752
Reverting the mode of action of the mitochondrial FOF1-ATPase by Legionella pneumophila preserves its replication niche. PMID:34882089
Inhibition of the PLK1-Coupled Cell Cycle Machinery Overcomes Resistance to Oxaliplatin in Colorectal Cancer. PMID:34881526
Centromere-Specific Retrotransposons and Very-Long-Chain Fatty Acid Biosynthesis in the Genome of Yellowhorn (Xanthoceras sorbifolium, Sapindaceae), an Oil-Producing Tree With Significant Drought Resistance. PMID:34880890
Histone Acetyltransferases and Deacetylases Are Required for Virulence, Conidiation, DNA Damage Repair, and Multiple Stresses Resistance of Alternaria alternata. PMID:34880849
Non-genetic determinants of malignant clonal fitness at single-cell resolution. PMID:34880496
A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer. PMID:34880227
Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications. PMID:34880204
The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites. PMID:34879056
Epigenetic Silencing of Recombinant Adeno-associated Virus Genomes by NP220 and the HUSH Complex. PMID:34878926
Analysis of the ARTIC Version 3 and Version 4 SARS-CoV-2 Primers and Their Impact on the Detection of the G142D Amino Acid Substitution in the Spike Protein. PMID:34878296
Host Lung Environment Limits Aspergillus fumigatus Germination through an SskA-Dependent Signaling Response. PMID:34878292
Whole-Genome Sequencing of Acer catalpifolium Reveals Evolutionary History of Endangered Species. PMID:34878129
Whole-Genome Sequencing Highlights Conservative Genomic Strategies of a Stress-Tolerant, Long-Lived Scleractinian Coral, Porites australiensis Vaughan, 1918. PMID:34878117
Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer. PMID:34877933
Coordinated Gene Expression and Chromatin Regulation during Hydra Head Regeneration. PMID:34877597
Functional organization of the maternal and paternal human 4D Nucleome. PMID:34877507
A computational pipeline for functional gene discovery. PMID:34876638
RiboPlotR: a visualization tool for periodic Ribo-seq reads. PMID:34876166
Coordinated repression of pro-differentiation genes via P-bodies and transcription maintains Drosophila intestinal stem cell identity. PMID:34875230
Frequency, composition and mobility of Escherichia coli-derived transposable elements in holdings of plasmid repositories. PMID:34875147
Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation. PMID:34874919
Identification of Drug Transporter Genomic Variants and Inhibitors That Protect Against Doxorubicin-Induced Cardiotoxicity. PMID:34874743
Analysis of long and short enhancers in melanoma cell states. PMID:34874265
Genome reorganization during emergence of host-associated Mycobacterium abscessus. PMID:34874249
Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic intervention. PMID:34873462
Medium levels of transcription and replication related chromosomal instability are associated with poor clinical outcome. PMID:34873180
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome. PMID:34873157
Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling. PMID:34872593
Male-biased migration from East Africa introduced pastoralism into southern Africa. PMID:34872534
VID22 counteracts G-quadruplex-induced genome instability. PMID:34871443
Chromatin-contact atlas reveals disorder-mediated protein interactions and moonlighting chromatin-associated RBPs. PMID:34871434
New Delhi Metallo-Beta-Lactamase Facilitates the Emergence of Cefiderocol Resistance in Enterobacter cloacae. PMID:34871093
Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach. PMID:34870593
SARS-CoV-2 genetic variations associated with COVID-19 pathogenicity. PMID:34870573
Identification of Genetic Predisposition in Noncirrhotic Portal Hypertension Patients With Multiple Renal Cysts by Integrated Analysis of Whole-Genome and Single-Cell RNA Sequencing. PMID:34868264
Genome-wide Identification and Analysis of Splicing QTLs in Multiple Sclerosis by RNA-Seq Data. PMID:34868258
Asymmetric Divergence in Transmitted SNPs of DNA Replication/Transcription and Their Impact on Gene Expression in Polyploid Brassica napus. PMID:34868229
High-Quality Genomes and High-Density Genetic Map Facilitate the Identification of Genes From a Weedy Rice. PMID:34868173
Insight Between the Epigenetics and Transcription Responding of Cotton Hypocotyl Cellular Elongation Under Salt-Alkaline Stress. PMID:34868171
Chromosome-Scale Reference Genome of Amphicarpaea edgeworthii: A New Resource for Amphicarpic Plants Research and Complex Flowering Pattern. PMID:34868169
Dissection of Quantitative Blackleg Resistance Reveals Novel Variants of Resistance Gene Rlm9 in Elite Brassica napus. PMID:34868134
Acute and Chronic Changes in Gene Expression After CMV DNAemia in Kidney Transplant Recipients. PMID:34867983
JAK2-STAT Epigenetically Regulates Tolerized Genes in Monocytes in the First Encounter With Gram-Negative Bacterial Endotoxins in Sepsis. PMID:34867954
Systematic Evaluation of Whole-Genome Sequencing Based Prediction of Antimicrobial Resistance in Campylobacter jejuni and C. coli. PMID:34867917
Mitochondrial DNA Content May Not Be a Reliable Screening Biomarker for Live Birth After Single Euploid Blastocyst Transfer. PMID:34867804
Candidates for Balancing Selection in Leishmania donovani Complex Parasites. PMID:34865011
Genome Sequence of Elaeagnus mollis, the First Chromosome-Level Genome of the Family Elaeagnaceae. PMID:34864990
Machine learning modeling of genome-wide copy number alteration signatures reliably predicts IDH mutational status in adult diffuse glioma. PMID:34863298
Epigenetic modifications potentially controlling the allelic expression of imprinted genes in sunflower endosperm. PMID:34863098
Rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressors. PMID:34862477
QTL mapping for low temperature germination in rapeseed. PMID:34862452
Find and cut-and-transfer (FiCAT) mammalian genome engineering. PMID:34862378
CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes. PMID:34862376
Histone acetylation regulates the expression of genes involved in worker reproduction in the ant Temnothorax rugatulus. PMID:34861814
An NK-like CAR T cell transition in CAR T cell dysfunction. PMID:34861191
bfc, a novel serpent co-factor for the expression of croquemort, regulates efferocytosis in Drosophila melanogaster. PMID:34860835
Thrice out of Asia and the adaptive radiation of the western honey bee. PMID:34860547
ECTyper: in silico Escherichia coli serotype and species prediction from raw and assembled whole-genome sequence data. PMID:34860150
PEPATAC: an optimized pipeline for ATAC-seq data analysis with serial alignments. PMID:34859208
Genomic Analysis of Multidrug-Resistant Mycobacterium tuberculosis Strains From Patients in Kazakhstan. PMID:34858467
Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1→3)-β-D-Glucan. PMID:34858388
Accelerating Complete Phytoplasma Genome Assembly by Immunoprecipitation-Based Enrichment and MinION-Based DNA Sequencing for Comparative Analyses. PMID:34858377
Recapitulating whole genome based population genetic structure for Indian wild tigers through an ancestry informative marker panel. PMID:34857925
GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors. PMID:34857890
Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis. PMID:34857762
An adaptive method of defining negative mutation status for multi-sample comparison using next-generation sequencing. PMID:34856988
Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence. PMID:34856941
Expression of transport proteins in the rete mirabile of european silver and yellow eel. PMID:34856920
Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops. PMID:34856126
Assessing BRCA1 activity in DNA damage repair using human induced pluripotent stem cells as an approach to assist classification of BRCA1 variants of uncertain significance. PMID:34855882
Coding-Complete Genome Sequences of Alpha and Delta SARS-CoV-2 Variants from Kamphaeng Phet Province, Thailand, from May to July 2021. PMID:34854728
Full Genome Sequence of a Methanomassiliicoccales Representative Enriched from Peat Soil. PMID:34854727
Trellis for efficient data and task management in the VA Million Veteran Program. PMID:34853358
IκBα is required for full transcriptional induction of some NFκB-regulated genes in response to TNF in MCF-7 cells. PMID:34853340
Histone variant H2A.Z regulates zygotic genome activation. PMID:34853314
SPEN is required for Xist upregulation during initiation of X chromosome inactivation. PMID:34853312
An ancient antimicrobial protein co-opted by a fungal plant pathogen for in planta mycobiome manipulation. PMID:34853168
KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs. PMID:34853079
A novel de novo hemizygous ARHGEF9 mutation associated with severe intellectual disability and epilepsy: a case report. PMID:34851771
Polyphenol Utilization Proteins in the Human Gut Microbiome. PMID:34851722
Effects of the Noncoding Subgenomic RNA of Red Clover Necrotic Mosaic Virus in Virus Infection. PMID:34851690
Phospho-RNA sequencing with circAID-p-seq. PMID:34850942
CRISPRroots: on- and off-target assessment of RNA-seq data in CRISPR-Cas9 edited cells. PMID:34850137
Master lineage transcription factors anchor trans mega transcriptional complexes at highly accessible enhancer sites to promote long-range chromatin clustering and transcription of distal target genes. PMID:34850122
The Drosophila HP1 family is associated with active gene expression across chromatin contexts. PMID:34849911
CLAMP regulates zygotic genome activation in Drosophila embryos. PMID:34849887
The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans. PMID:34849863
Clonal evolution in serially passaged Cryptococcus neoformans × deneoformans hybrids reveals a heterogenous landscape of genomic change. PMID:34849836
Chromosome assembled and annotated genome sequence of Aspergillus flavus NRRL 3357. PMID:34849826
Genomic diversity, chromosomal rearrangements, and interspecies hybridization in the Ogataea polymorpha species complex. PMID:34849824
Stability of DNA methylation and chromatin accessibility in structurally diverse maize genomes. PMID:34849810
A reference genome for the nectar-robbing Black-throated Flowerpiercer (Diglossa brunneiventris). PMID:34849784
Mutation rate and spectrum in obligately outcrossing Caenorhabditis elegans mutation accumulation lines subjected to RNAi-induced knockdown of the mismatch repair gene msh-2. PMID:34849777
A dense linkage map for a large repetitive genome: discovery of the sex-determining region in hybridizing fire-bellied toads (Bombina bombina and Bombina variegata). PMID:34849761
Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs. PMID:34848725
SISTER OF TM3 activates FRUITFULL1 to regulate inflorescence branching in tomato. PMID:34848688
The Cymbidium genome reveals the evolution of unique morphological traits. PMID:34848682
Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers. PMID:34848534
RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response. PMID:34848435
Genomic monitoring of the SARS-CoV-2 B1.1.7 (WHO VOC Alpha) in the Sao Paulo state, Brazil. PMID:34848213
A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15. PMID:34846534
Phylogenomics and population genomics of SARS-CoV-2 in Mexico during the pre-vaccination stage reveals variants of interest B.1.1.28.4 and B.1.1.222 or B.1.1.519 and the nucleocapsid mutation S194L associated with symptoms. PMID:34846283
Successful Profiling of Plasmodium falciparum var Gene Expression in Clinical Samples via a Custom Capture Array. PMID:34846163
Short-read and long-read RNA sequencing of mouse hematopoietic stem cells at bulk and single-cell levels. PMID:34845251
Heterochromatin is a quantitative trait associated with spontaneous epiallele formation. PMID:34845222
Identification and in vitro validation of neoantigens for immune activation against high-risk pediatric leukemia cells. PMID:34844524
Toll-Like Receptor (TLR) Signaling Enables Cyclic GMP-AMP Synthase (cGAS) Sensing of HIV-1 Infection in Macrophages. PMID:34844429
Chikungunya Virus Infects the Heart and Induces Heart-Specific Transcriptional Changes in an Immunodeficient Mouse Model of Infection. PMID:34844209
Establishment of quantitative RNAi-based forward genetics in Entamoeba histolytica and identification of genes required for growth. PMID:34843592
Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis. PMID:34843512
Nucleo-cytoplasmic RNA distribution responsible for maintaining neuroinflammatory microenvironment. PMID:34843419
Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism. PMID:34842276
Deletion of a cyclin-dependent protein kinase inhibitor, CsSMR1, leads to dwarf and determinate growth in cucumber (Cucumis sativus L.). PMID:34841478
A next generation sequencing (NGS) analysis to reveal genomic and proteomic mutation landscapes of SARS-CoV-2 in South Asia. PMID:34841355
Translational demand is not a major source of plasmid-associated fitness costs. PMID:34839712
Diversification of plasmids in a genus of pathogenic and nitrogen-fixing bacteria. PMID:34839700
EvalDNA: a machine learning-based tool for the comprehensive evaluation of mammalian genome assembly quality. PMID:34837948
Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells. PMID:34837026
Chloranthus genome provides insights into the early diversification of angiosperms. PMID:34836973
Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. PMID:34836952
Population analysis of retrotransposons in giraffe genomes supports RTE decline and widespread LINE1 activity in Giraffidae. PMID:34836553
Minnesota peat viromes reveal terrestrial and aquatic niche partitioning for local and global viral populations. PMID:34836550
Phylogenetic Analysis Reveals Source Attribution Patterns for Campylobacter spp. in Tennessee and Pennsylvania. PMID:34835426
Complete Genome Analysis of Undecylprodigiosin Pigment Biosynthesizing Marine Streptomyces Species Displaying Potential Bioactive Applications. PMID:34835376
A Combination of M50I and V151I Polymorphic Mutations in HIV-1 Subtype B Integrase Results in Defects in Autoprocessing. PMID:34835137
Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection. PMID:34835095
Heterogeneity in the Response of Different Subtypes of Drosophila melanogaster Midgut Cells to Viral Infections. PMID:34835089
Identification of Cacao Mild Mosaic Virus (CaMMV) and Cacao Yellow Vein-Banding Virus (CYVBV) in Cocoa (Theobroma cacao) Germplasm. PMID:34834959
Evaluating Large Spontaneous Deletions in a Bovine Cell Line Selected for Bovine Viral Diarrhea Virus Resistance. PMID:34834954
Clusters of SARS-CoV-2 Lineage B.1.1.7 Infection after Vaccination with Adenovirus-Vectored and Inactivated Vaccines. PMID:34834934
Direct RNA Sequencing Reveals SARS-CoV-2 m6A Sites and Possible Differential DRACH Motif Methylation among Variants. PMID:34834915
Comparative Analysis of Genotyping by Sequencing and Whole-Genome Sequencing Methods in Diversity Studies of Olea europaea L. PMID:34834877
Genotyping-by-Sequencing Derived Genetic Linkage Map and Quantitative Trait Loci for Sugar Content in Onion (Allium cepa L.). PMID:34834630
Transcriptome Analysis of Lolium temulentum Exposed to a Combination of Drought and Heat Stress. PMID:34834610
PharmVIP: A Web-Based Tool for Pharmacogenomic Variant Analysis and Interpretation. PMID:34834582
Loss of Endothelial Barrier Function in the Inflammatory Setting: Indication for a Cytokine-Mediated Post-Transcriptional Mechanism by Virtue of Upregulation of miRNAs miR-29a-3p, miR-29b-3p, and miR-155-5p. PMID:34831066
Cancer Detection and Classification by CpG Island Hypermethylation Signatures in Plasma Cell-Free DNA. PMID:34830765
Enhancer RNA Profiling in Smoking and HPV Associated HNSCC Reveals Associations to Key Oncogenes. PMID:34830428
Molecular Analysis Uncovers the Mechanism of Fertility Restoration in Temperature-Sensitive Polima Cytoplasmic Male-Sterile Brassica napus. PMID:34830333
In-Depth Sequence Analysis of Bread Wheat VRN1 Genes. PMID:34830166
Danish Whole-Genome-Sequenced Candida albicans and Candida glabrata Samples Fit into Globally Prevalent Clades. PMID:34829249
Characterization of Genetically Modified Microorganisms Using Short- and Long-Read Whole-Genome Sequencing Reveals Contaminations of Related Origin in Multiple Commercial Food Enzyme Products. PMID:34828918
Selective Sweeps and Polygenic Adaptation Drive Local Adaptation along Moisture and Temperature Gradients in Natural Populations of Coast Redwood and Giant Sequoia. PMID:34828432
Comparative RNA-Seq Analysis Reveals Potentially Resistance-Related Genes in Response to Bacterial Canker of Tomato. PMID:34828351
Genomic Signatures of Domestication Selection in the Australasian Snapper (Chrysophrys auratus). PMID:34828341
A Non-Shedding Fruit Elaeis oleifera Palm Reveals Perturbations to Hormone Signaling, ROS Homeostasis, and Hemicellulose Metabolism. PMID:34828330
De novo assembly, transcriptome characterization and marker discovery in Indian major carp, Labeo rohita through pyrosequencing. PMID:34825293
The Tien Shan vole (Microtus ilaeus; Rodentia: Cricetidae) as a new species in the Late Pleistocene of Europe. PMID:34824815
Persistence and plasticity in bacterial gene regulation. PMID:34824476
Hybrid de novo genome-reassembly reveals new insights on pathways and pathogenicity determinants in rice blast pathogen Magnaporthe oryzae RMg_Dl. PMID:34824307
Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α. PMID:34824281
The telomere length landscape of prostate cancer. PMID:34824250
A supergene underlies linked variation in color and morphology in a Holarctic songbird. PMID:34824228
Molecular mechanisms and topological consequences of drastic chromosomal rearrangements of muntjac deer. PMID:34824214
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture. PMID:34824211
Plasma virome and the risk of blood-borne infection in persons with substance use disorder. PMID:34824209
Remarkably coherent population structure for a dominant Antarctic Chlorobium species. PMID:34823595
Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing. PMID:34823554
Identification of factors related to immunotherapy efficacy and prognosis in patients with advanced head and neck squamous cell carcinoma. PMID:34823553
Identification of novel QTL contributing to barley yellow mosaic resistance in wild barley (Hordeum vulgare spp. spontaneum). PMID:34823470
Genetic Responses and Aflatoxin Inhibition during Co-Culture of Aflatoxigenic and Non-Aflatoxigenic Aspergillus flavus. PMID:34822579
PpMYB36 Encodes a MYB-Type Transcription Factor That Is Involved in Russet Skin Coloration in Pear (Pyrus pyrifolia). PMID:34819942
Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis. PMID:34819643
Benchmarking different approaches for Norovirus genome assembly in metagenome samples. PMID:34819031
Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected. PMID:34818059
The 40S-LARP1 complex reprograms the cellular translatome upon mTOR inhibition to preserve the protein synthetic capacity. PMID:34818049
Predicting master transcription factors from pan-cancer expression data. PMID:34818047
Phylogenetic Distribution of WhiB- and Lsr2-Type Regulators in Actinobacteriophage Genomes. PMID:34817283
Whole-Genome Sequences of SARS-CoV-2 Isolates from the Dominican Republic. PMID:34817214
Identifying tumorigenic non-coding mutations through altered cis-regulation. PMID:34816127
Bottleneck-associated changes in the genomic landscape of genetic diversity in wild lynx populations. PMID:34815746
Population dynamics linked to glacial cycles in Cercis chuniana F. P. Metcalf (Fabaceae) endemic to the montane regions of subtropical China. PMID:34815745
Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and associated humans in the Netherlands. PMID:34815406
Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits. PMID:34815310
Comprehensive determination of transcription start sites derived from all RNA polymerases using ReCappable-seq. PMID:34815308
Comparative morphological, physiological, biochemical and genomic studies reveal novel genes of Dunaliella bioculata and D. quartolecta in response to salt stress. PMID:34813000
Maturation of 23S rRNA includes removal of helix H1 in many bacteria. PMID:34812116
HaplotypeTools: a toolkit for accurately identifying recombination and recombinant genotypes. PMID:34809571
trioPhaser: using Mendelian inheritance logic to improve genomic phasing of trios. PMID:34809557
The architecture of the simian varicella virus transcriptome. PMID:34807956
Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes. PMID:34806773
Role of endothelial cells in pulmonary fibrosis via SREBP2 activation. PMID:34806652
EpiDiverse Toolkit: a pipeline suite for the analysis of bisulfite sequencing data in ecological plant epigenetics. PMID:34805989
Ancient genome analyses shed light on kinship organization and mating practice of Late Neolithic society in China. PMID:34805800
uPIC-M: Efficient and Scalable Preparation of Clonal Single Mutant Libraries for High-Throughput Protein Biochemistry. PMID:34805683
Cataloging Human PRDM9 Allelic Variation Using Long-Read Sequencing Reveals PRDM9 Population Specificity and Two Distinct Groupings of Related Alleles. PMID:34805134
Towards a Cost-Effective Implementation of Genomic Prediction Based on Low Coverage Whole Genome Sequencing in Dezhou Donkey. PMID:34804115
Comparative Analysis of Chloroplast Genomes of Seven Chaetoceros Species Revealed Variation Hotspots and Speciation Time. PMID:34803961
Candidate Effectors of Plasmodiophora brassicae Pathotype 5X During Infection of Two Brassica napus Genotypes. PMID:34803960
The Piezo-Hyperthermophilic Archaeon Thermococcus piezophilus Regulates Its Energy Efficiency System to Cope With Large Hydrostatic Pressure Variations. PMID:34803948
Heterospecific Neighbor Plants Impact Root Microbiome Diversity and Molecular Function of Root Fungi. PMID:34803937
Identification of differentially expressed genomic repeats in primary hepatocellular carcinoma and their potential links to biological processes and survival. PMID:34803457
β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia. PMID:34799994
Interplay between copy number alterations and immune profiles in the early breast cancer Scandinavian Breast Group 2004-1 randomized phase II trial: results from a feasibility study. PMID:34799582
COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types. PMID:34799557
SARS-CoV-2 introduction and lineage dynamics across three epidemic peaks in Southern Brazil: massive spread of P.1. PMID:34798321
5' Half of specific tRNAs feeds back to promote corresponding tRNA gene transcription in vertebrate embryos. PMID:34797706
Serotypes, Virulence-Associated Factors, and Antimicrobial Resistance of Streptococcus suis Isolates Recovered From Sick and Healthy Pigs Determined by Whole-Genome Sequencing. PMID:34796225
Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target. PMID:34796107
Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection. PMID:34795443
Metagenome-assembled genomes and gene catalog from the chicken gut microbiome aid in deciphering antibiotic resistomes. PMID:34795385
Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics. PMID:34795375
Interploidy gene flow involving the sexual-asexual cycle facilitates the diversification of gynogenetic triploid Carassius fish. PMID:34795357
Diversity, multifaceted evolution, and facultative saprotrophism in the European Batrachochytrium salamandrivorans epidemic. PMID:34795258
Jumper enables discontinuous transcript assembly in coronaviruses. PMID:34795232
The web-based multiplex PCR primer design software Ultiplex and the associated experimental workflow: up to 100- plex multiplicity. PMID:34794394
Genome surveillance by HUSH-mediated silencing of intronless mobile elements. PMID:34794168
Yersinia remodels epigenetic histone modifications in human macrophages. PMID:34793580
Extraction and high-throughput sequencing of oak heartwood DNA: Assessing the feasibility of genome-wide DNA methylation profiling. PMID:34793449
Genome-wide mapping of G-quadruplex structures with CUT&Tag. PMID:34792172
Transcriptional profile and chromatin accessibility in zebrafish melanocytes and melanoma tumors. PMID:34791221
FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets. PMID:34791203
Transmission distortion and genetic incompatibilities between alleles in a multigenerational mouse advanced intercross line. PMID:34791189
Metatranscriptomics to characterize respiratory virome, microbiome, and host response directly from clinical samples. PMID:34790908
Metagenomic Analysis of Biocide-Treated Neotropical Oil Reservoir Water Unveils Microdiversity of Thermophile Tepidiphilus. PMID:34790180
Cell-type specialization is encoded by specific chromatin topologies. PMID:34789882
Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors. PMID:34789735
Adaptive divergence in shoot gravitropism creates hybrid sterility in an Australian wildflower. PMID:34789571
Development and validation of an expanded targeted sequencing panel for non-invasive prenatal diagnosis of sporadic skeletal dysplasia. PMID:34789231
The landscape of coding RNA editing events in pediatric cancer. PMID:34789196
SCYN: single cell CNV profiling method using dynamic programming. PMID:34789142
A de novo genome assembly and annotation of the southern flying squirrel (Glaucomys volans). PMID:34788821
Genetic Diversity in Chimpanzee Transcriptomics Does Not Represent Wild Populations. PMID:34788801
Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina. PMID:34788628
Genomic transformation and social organization during the Copper Age-Bronze Age transition in southern Iberia. PMID:34788096
Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models. PMID:34788094
The lungfish cocoon is a living tissue with antimicrobial functions. PMID:34788085
RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2. PMID:32286294
Unraveling Fe(II)-Oxidizing Mechanisms in a Facultative Fe(II) Oxidizer, Sideroxydans lithotrophicus Strain ES-1, via Culturing, Transcriptomics, and Reverse Transcription-Quantitative PCR. PMID:34788064
Single-Point Mutations in the N Gene of SARS-CoV-2 Adversely Impact Detection by a Commercial Dual Target Diagnostic Assay. PMID:34787486
Deciphering Multidrug-Resistant Acinetobacter baumannii from a Pediatric Cancer Hospital in Egypt. PMID:34787450
Comparing gut resistome composition among patients with acute Campylobacter infections and healthy family members. PMID:34785751
Resequencing of 388 cassava accessions identifies valuable loci and selection for variation in heterozygosity. PMID:34784936
Preparation of optimized concanavalin A-conjugated Dynabeads® magnetic beads for CUT&Tag. PMID:34784358
Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP. PMID:34784250
Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells. PMID:34783649
MoG+: a database of genomic variations across three mouse subspecies for biomedical research. PMID:34782917
Compendium of 530 metagenome-assembled bacterial and archaeal genomes from the polar Arctic Ocean. PMID:34782724
Bioarchaeological insights into the last plague of Imola (1630-1632). PMID:34782694
Genome-wide association study reveals genetic variants associated with HIV-1C infection in a Botswana study population. PMID:34782459
Assessment of in vitro activities of novel modified antimicrobial peptides against clarithromycin resistant Mycobacterium abscessus. PMID:34780520
Decreased Methylenetetrahydrofolate Reductase Activity Leads to Increased Sensitivity to para-Aminosalicylic Acid in Mycobacterium tuberculosis. PMID:34780266
Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia. PMID:34778800
Evaluation of the MGISEQ-2000 Sequencing Platform for Illumina Target Capture Sequencing Libraries. PMID:34777467
Chromosome-Level Genome Assembly Reveals Significant Gene Expansion in the Toll and IMD Signaling Pathways of Dendrolimus kikuchii. PMID:34777464
Identification and Characterization of NBS Resistance Genes in Akebia trifoliata. PMID:34777439
Mutagenic Effect of Proton Beams Characterized by Phenotypic Analysis and Whole Genome Sequencing in Arabidopsis. PMID:34777430
Genomic Epidemiology and Antimicrobial Susceptibility Profile of Enterotoxigenic Escherichia coli From Outpatients With Diarrhea in Shenzhen, China, 2015-2020. PMID:34777281
Genetic region responsible for the differences of starch properties in two glutinous rice cultivars in Hokkaido, Japan. PMID:34776744
Sat-BSA: an NGS-based method using local de novo assembly of long reads for rapid identification of genomic structural variations associated with agronomic traits. PMID:34776737
Identification of Feline Foamy Virus-derived MicroRNAs. PMID:34776460
Accurate long-read de novo assembly evaluation with Inspector. PMID:34775997
Single-cell RNA Sequencing Reveals Thoracolumbar Vertebra Heterogeneity and Rib-genesis in Pigs. PMID:34775075
RNA-seq driven expression and enrichment analysis to investigate CVD genes with associated phenotypes among high-risk heart failure patients. PMID:34774109
In depth analysis of Cyprus-specific mutations of SARS-CoV-2 strains using computational approaches. PMID:34773976
Identification of an Elite Core Panel as a Key Breeding Resource to Accelerate the Rate of Genetic Improvement for Irrigated Rice. PMID:34773509
The barley mutant multiflorus2.b reveals quantitative genetic variation for new spikelet architecture. PMID:34773464
Genome of the estuarine oyster provides insights into climate impact and adaptive plasticity. PMID:34773106
Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication. PMID:34773064
Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males. PMID:34772938
Fast alignment and preprocessing of chromatin profiles with Chromap. PMID:34772935
Genomic Analysis of Mycobacterium tuberculosis Isolates and Construction of a Beijing Lineage Reference Genome. PMID:31971587
Linked supergenes underlie split sex ratio and social organization in an ant. PMID:34772805
Long-read sequencing settings for efficient structural variation detection based on comprehensive evaluation. PMID:34772337
Mitochondrial genomes of two parasitic Cuscuta species lack clear evidence of horizontal gene transfer and retain unusually fragmented ccmFC genes. PMID:34772334
Low-Coverage Whole Genome Sequencing Using Laser Capture Microscopy with Combined Digital Droplet PCR: An Effective Tool to Study Copy Number and Kras Mutations in Early Lung Adenocarcinoma Development. PMID:34769463
From Forensics to Clinical Research: Expanding the Variant Calling Pipeline for the Precision ID mtDNA Whole Genome Panel. PMID:34769461
Fibroblast Differentiation and Matrix Remodeling Impaired under Simulated Microgravity in 3D Cell Culture Model. PMID:34769342
Germline POT1 Deregulation Can Predispose to Myeloid Malignancies in Childhood. PMID:34769003
Expression Pattern of Purinergic Signaling Components in Colorectal Cancer Cells and Differential Cellular Outcomes Induced by Extracellular ATP and Adenosine. PMID:34768902
Genetic Variation in ABCC4 and CFTR and Acute Pancreatitis during Treatment of Pediatric Acute Lymphoblastic Leukemia. PMID:34768335
DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice. PMID:34767618
Tumor immune microenvironment is influenced by frameshift mutations and tumor mutational burden in gastric cancer. PMID:34767183
Single-strand specific nuclease enhances accuracy of error-corrected sequencing and improves rare mutation-detection sensitivity. PMID:34767040
The high diversity of SARS-CoV-2-related coronaviruses in pangolins alerts potential ecological risks. PMID:34766482
Competition dynamics in long-term propagations of Schizosaccharomyces pombe strain communities. PMID:34765162
Genome-wide SNP identification in Fraxinus linking genetic characteristics to tolerance of Agrilus planipennis. PMID:34765140
Large- and small-scale geographic structures affecting genetic patterns across populations of an Alpine butterfly. PMID:34765135
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells. PMID:34764490
Towards inferring nanopore sequencing ionic currents from nucleotide chemical structures. PMID:34764310
Structural variants in the Chinese population and their impact on phenotypes, diseases and population adaptation. PMID:34764282
Focal amplifications are associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma. PMID:34764264
Long-read assembly and comparative evidence-based reanalysis of Cryptosporidium genome sequences reveal expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions. PMID:34764149
Comprehensive characterization of single-cell full-length isoforms in human and mouse with long-read sequencing. PMID:34763716
Multiomics study of a heterotardigrade, Echinisicus testudo, suggests the possibility of convergent evolution of abundant heat-soluble proteins in Tardigrada. PMID:34763673
DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma. PMID:34762643
Complete Mitochondrial Genome Sequences of Nine Aspergillus flavus Strains. PMID:34761953
Characterization of Globodera ellingtonae Populations from Chile Utilizing Whole Genome Sequencing. PMID:34761229
Assessment of antimycobacterial activities of pure compounds extracted from Thai medicinal plants against clarithromycin-resistant Mycobacterium abscessus. PMID:34760385
Global RNA editing identification and characterization during human pluripotent-to-cardiomyocyte differentiation. PMID:34760335
Functional genomics data: privacy risk assessment and technological mitigation. PMID:34759381
Triangulation supports agricultural spread of the Transeurasian languages. PMID:34759322
A chickpea genetic variation map based on the sequencing of 3,366 genomes. PMID:34759320
Diverse alterations associated with resistance to KRAS(G12C) inhibition. PMID:34759319
Temporal transitions in the post-mitotic nervous system of Caenorhabditis elegans. PMID:34759317
Self-guarding of MORC3 enables virulence factor-triggered immunity. PMID:34759314
The cell-surface 5'-nucleotidase CD73 defines a functional T memory cell subset that declines with age. PMID:34758299
Resolving the Microalgal Gene Landscape at the Strain Level: a Novel Hybrid Transcriptome of Emiliania huxleyi CCMP3266. PMID:34757817
Clinical Utility of SARS-CoV-2 Whole Genome Sequencing in Deciphering Source of Infection. PMID:34756867
The impact of maternal age on gene expression during the GV to MII transition in euploid human oocytes. PMID:34755188
High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy. PMID:34755130
Genome profiles of pathologist-defined cell clusters by multiregional LCM and G&T-seq in one triple-negative breast cancer patient. PMID:34755126
Genetic characteristics of a patient with multiple primary cancers: A case report. PMID:34754869
Identification of genes and gene expression associated with dispersal capacity in the mountain pine beetle, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae). PMID:34754626
Molecular epidemiology of peste des petits ruminants virus emergence in critically endangered Mongolian saiga antelope and other wild ungulates. PMID:34754511
Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders. PMID:34753942
Mouse strain-specific polymorphic provirus functions as cis-regulatory element leading to epigenomic and transcriptomic variations. PMID:34753915
Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c. PMID:34752747
Impact of extrinsic incubation temperature on natural selection during Zika virus infection of Aedes aegypti and Aedes albopictus. PMID:34752502
Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle. PMID:34752468
Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole. PMID:34752454
Exploring bacterial diversity via a curated and searchable snapshot of archived DNA sequences. PMID:34752446
Genome structural variation in Escherichia coli O157:H7. PMID:34751643
Genetic and genomic architecture in eight strains of the laboratory opossum Monodelphis domestica. PMID:34751383
Lateral transduction is inherent to the life cycle of the archetypical Salmonella phage P22. PMID:34751192
Cohesin regulates homology search during recombinational DNA repair. PMID:34750581
Novel findings from family-based exome sequencing for children with biliary atresia. PMID:34750413
Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia. PMID:34750374
Cell division in the shoot apical meristem is a trigger for miR156 decline and vegetative phase transition in Arabidopsis. PMID:34750273
An alternative splicing signature in human Crohn's disease. PMID:34749666
VarGoats project: a dataset of 1159 whole-genome sequences to dissect Capra hircus global diversity. PMID:34749642
Spatial and Functional Organization of Human Papillomavirus Replication Foci in the Productive Stage of Infection. PMID:34749533
The FASTK family proteins fine-tune mitochondrial RNA processing. PMID:34748562
Mutation rate dynamics reflect ecological change in an emerging zoonotic pathogen. PMID:34748531
A genome-phenome association study in native microbiomes identifies a mechanism for cytosine modification in DNA and RNA. PMID:34747693
Genome editing reveals that pSCL4 is required for chromosome linearity in Streptomyces clavuligerus. PMID:34747689
Pol3Base: a resource for decoding the interactome, expression, evolution, epitranscriptome and disease variations of Pol III-transcribed ncRNAs. PMID:34747466
Genomic analysis of 600 vancomycin-resistant Enterococcus faecium reveals a high prevalence of ST80 and spread of similar vanA regions via IS1216E and plasmid transfer in diverse genetic lineages in Ireland. PMID:34747439
Barriers and corridors of gene flow in an urbanized tropical reef system. PMID:34745340
Rapid adaptation through genomic and epigenomic responses following translocations in an endangered salmonid. PMID:34745338
SeekFusion - A Clinically Validated Fusion Transcript Detection Pipeline for PCR-Based Next-Generation Sequencing of RNA. PMID:34745213
Genome-Wide Association Study of Growth Performance and Immune Response to Newcastle Disease Virus of Indigenous Chicken in Rwanda. PMID:34745207
Uncovering Key Metabolic Determinants of the Drug Interactions Between Trimethoprim and Erythromycin in Escherichia coli. PMID:34745067
Comparative methylation and RNA-seq expression analysis in CpG context to identify genes involved in Backfat vs. Liver diversification in Nanchukmacdon Pig. PMID:34743693
Universal activity-based labeling method for ammonia- and alkane-oxidizing bacteria. PMID:34743174
Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function. PMID:34742737
Hybridization-proximity labeling reveals spatially ordered interactions of nuclear RNA compartments. PMID:34741808
Potentiating antibiotic efficacy via perturbation of non-essential gene expression. PMID:34741116
Massively parallel interrogation of protein fragment secretability using SECRiFY reveals features influencing secretory system transit. PMID:34741024
Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila. PMID:34740250
Evaluation of WGS performance for bacterial pathogen characterization with the Illumina technology optimized for time-critical situations. PMID:34739368
Effects of Long-Term In Vitro Expansion on Genetic Stability and Tumor Formation Capacity of Stem Cells. PMID:34738209
Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer. PMID:34738089
PRD-Containing Virulence Regulators (PCVRs) in Pathogenic Bacteria. PMID:34737980
Comparative Signatures of Selection Analyses Identify Loci Under Positive Selection in the Murrah Buffalo of India. PMID:34737760
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus. PMID:34737427
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen. PMID:34737275
Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling. PMID:34737269
Effects of rrm1 on NNV Resistance Revealed by RNA-seq and Gene Editing. PMID:34735644
Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge. PMID:34735434
Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells. PMID:34734806
Genome, Transcriptome, and Germplasm Sequencing Uncovers Functional Variation in the Warm-Season Grain Legume Horsegram Macrotyloma uniflorum (Lam.) Verdc. PMID:34733308
Emerging Severe Acute Respiratory Syndrome Coronavirus 2 Mutation Hotspots Associated With Clinical Outcomes and Transmission. PMID:34733263
Terrestrial-type nitrogen-fixing symbiosis between seagrass and a marine bacterium. PMID:34732889
Underwater CAM photosynthesis elucidated by Isoetes genome. PMID:34732722
Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation. PMID:34732258
Sex without crossing over in the yeast Saccharomycodes ludwigii. PMID:34732243
Genome and transcriptome-based characterization of high energy carbon-ion beam irradiation induced delayed flower senescence mutant in Lotus japonicus. PMID:34732128
Transcriptome profiling reveals the developmental regulation of NaCl-treated Forcipomyia taiwana eggs. PMID:34732124
Interpreting Viral Deep Sequencing Data with GLUE. PMID:30987147
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection. PMID:34731648
Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors. PMID:34731634
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome. PMID:34731631
Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription. PMID:34731603
Uncovering Bleomycin-Induced Genomic Alterations and Underlying Mechanisms in the Yeast Saccharomyces cerevisiae. PMID:34731050
Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression. PMID:34730997
Evaluating de Novo Assembly and Binning Strategies for Time Series Drinking Water Metagenomes. PMID:34730411
Molecular Analysis of blaKPC-2-Harboring Plasmids: Tn4401a Interplasmid Transposition and Tn4401a-Carrying ColRNAI Plasmid Mobilization from Klebsiella pneumoniae to Citrobacter europaeus and Morganella morganii in a Single Patient. PMID:34730375
Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections. PMID:34730297
Comprehensive understanding of Tn5 insertion preference improves transcription regulatory element identification. PMID:34729473
The genome of New Zealand trevally (Carangidae: Pseudocaranx georgianus) uncovers a XY sex determination locus. PMID:34727894
Impact of model assumptions on demographic inferences: the case study of two sympatric mouse lemurs in northwestern Madagascar. PMID:34727890
Genome-Wide Allele-Specific Expression in Obligately Asexual Daphnia pulex and the Implications for the Genetic Basis of Asexuality. PMID:34726699
High rates of evolution preceded shifts to sex-biased gene expression in Leucadendron, the most sexually dimorphic angiosperms. PMID:34726596
Emergence of Ceftazidime- and Avibactam-Resistant Klebsiella pneumoniae Carbapenemase-Producing Pseudomonas aeruginosa in China. PMID:34726488
Genome-wide data from the Bubi of Bioko Island clarifies the Atlantic fringe of the Bantu dispersal. PMID:30841922
Epidemiological dynamics of SARS-CoV-2 VOC Gamma in Rio de Janeiro, Brazil. PMID:34725568
Haplotype-aware variant calling with PEPPER-Margin-DeepVariant enables high accuracy in nanopore long-reads. PMID:34725481
High molecular weight glutenin gene diversity in Aegilops tauschii demonstrates unique origin of superior wheat quality. PMID:34725451
Practical approach to detection and surveillance of emerging highly resistant Mycobacterium tuberculosis Beijing 1071-32-cluster. PMID:34725411
Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals. PMID:34724962
Surfactin Stimulated by Pectin Molecular Patterns and Root Exudates Acts as a Key Driver of the Bacillus-Plant Mutualistic Interaction. PMID:34724831
Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation. PMID:34724812
FOXR1 regulates stress response pathways and is necessary for proper brain development. PMID:34723967
A nuclear pore sub-complex restricts the propagation of Ty retrotransposons by limiting their transcription. PMID:34723966
Timing RNA polymerase pausing with TV-PRO-seq. PMID:34723238
Isolation of high-quality total RNA and RNA sequencing of single bovine oocytes. PMID:34723212
Superenhancer-transcription factor regulatory network in malignant tumors. PMID:34722892
Characterization of Long Non-coding RNAs Modified by m6A RNA Methylation in Skeletal Myogenesis. PMID:34722547
Application of Machine Learning Classifier to Candida auris Drug Resistance Analysis. PMID:34722336
Scientific Guidance for the submission of dossiers on Food Enzymes. PMID:34721697
Ancient Mitogenomes Provide New Insights into the Origin and Early Introduction of Chinese Domestic Donkeys. PMID:34721545
Genetic and Molecular Analysis of Root Hair Development in Arabis alpina. PMID:34721494
Identification of Candidate Genes for Self-Compatibility in Perennial Ryegrass (Lolium perenne L.). PMID:34721449
Graft-Versus-Host Disease Prevention by In Vitro-Generated Myeloid-Derived Suppressor Cells Is Exclusively Mediated by the CD11b+CD11c+ MDSC Subpopulation. PMID:34721430
Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing. PMID:34721349
Characterization of Basal Transcriptomes Identifies Potential Metabolic and Virulence-Associated Adaptations Among Diverse Nontyphoidal Salmonella enterica Serovars. PMID:34721328
Identification of a novel sex determining chromosome in cichlid fishes that acts as XY or ZW in different lineages. PMID:34720170
The APETALA2 homolog CaFFN regulates flowering time in pepper. PMID:34719686
High-quality reference genome and annotation aids understanding of berry development for evergreen blueberry (Vaccinium darrowii). PMID:34719668
ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition. PMID:34718742
Similarity-Based Analysis of Allele Frequency Distribution among Multiple Populations Identifies Adaptive Genomic Structural Variants. PMID:34718708
Analysis of Sex Chromosome Evolution in the Clade Palaeognathae from Phased Genome Assembly. PMID:34718546
DeepMP: a deep learning tool to detect DNA base modifications on Nanopore sequencing data. PMID:34718417
Distinct patterns of whole blood transcriptional responses are induced in mice following immunisation with adenoviral and poxviral vector vaccines encoding the same antigen. PMID:34717548
SARS-CoV-2 surveillance in Italy through phylogenomic inferences based on Hamming distances derived from pan-SNPs, -MNPs and -InDels. PMID:34717546
Genome and systems biology of Melilotus albus provides insights into coumarins biosynthesis. PMID:34717292
Fine mapping of the tiller inhibition gene TIN4 contributing to ideal plant architecture in common wheat. PMID:34716761
A Novel SCA3 Knock-in Mouse Model Mimics the Human SCA3 Disease Phenotype Including Neuropathological, Behavioral, and Transcriptional Abnormalities Especially in Oligodendrocytes. PMID:34716557
Non-vernalization requirement in Chinese kale caused by loss of BoFLC and low expressions of its paralogs. PMID:34716468
Clinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host. PMID:34716338
Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture. PMID:34716321
Transmission of multidrug-resistant tuberculosis in Shimen community in Shanghai, China: a molecular epidemiology study. PMID:34715793
isoCNV: in silico optimization of copy number variant detection from targeted or exome sequencing data. PMID:34715772
Genetic structure of immunologically associated candidate genes suggests arctic rabies variants exert differential selection in arctic fox populations. PMID:34714859
Molecular characterization of porcine epidemic diarrhoea virus (PEDV) in Poland reveals the presence of swine enteric coronavirus (SeCoV) sequence in S gene. PMID:34714840
The open pan-genome architecture and virulence landscape of Mycobacterium bovis. PMID:34714230
Kouprey (Bos sauveli) genomes unveil polytomic origin of wild Asian Bos. PMID:34712923
The first transcriptome sequencing and data analysis of the Javan mahseer (Tor tambra). PMID:34712757
Genomic and Transcriptomic Insight of Giant Sclerotium Formation of Wood-Decay Fungi. PMID:34712214
Pharmacogenomics characterization of the MDM2 inhibitor MI-773 reveals candidate tumours and predictive biomarkers. PMID:34711913
Characterization of hormone-producing cell types in the teleost pituitary gland using single-cell RNA-seq. PMID:34711832
Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming. PMID:34711814
BAMboozle removes genetic variation from human sequence data for open data sharing. PMID:34711808
A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells. PMID:34711176
Multivariate genome-wide association study of leaf shape in a Populus deltoides and P. simonii F1 pedigree. PMID:34710178
Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor. PMID:34710089
The proliferation role of LH on porcine primordial germ cell-like cells (pPGCLCs) through ceRNA network construction. PMID:34709759
Identification of Essential Genes in Caenorhabditis elegans with Lethal Mutations Maintained by Genetic Balancers. PMID:34709626
A Proposed Framework to Identify Dispensable and Essential Functions in Bifidobacteria: Case Study of Bifidobacterium breve UCC2003 as a Prototype of Its Genus. PMID:34709622
Using Genome Scale Mutant Libraries to Identify Essential Genes. PMID:34709619
Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia. PMID:34709177
Contiguous Genome Sequence of Frankia sp. Strain ArI3, Isolated from Root Nodules of Alnus rubra Bong. PMID:34709056
Genome Sequences of West Nile Virus Reference Materials. PMID:34709054
Integrative growth physiology and transcriptome profiling of probiotic Limosilactobacillus reuteri KUB-AC5. PMID:34707932
The mitogenome of Halotydeus destructor (Tucker) and its relationships with other trombidiform mites as inferred from nucleotide sequences and gene arrangements. PMID:34707848
50,000 years of ice and seals: Impacts of the Last Glacial Maximum on Antarctic fur seals. PMID:34707834
Characterization of Frond and Flower Development and Identification of FT and FD Genes From Duckweed Lemna aequinoctialis Nd. PMID:34707626
Mycoplasma genitalium and M. pneumoniae Regulate a Distinct Set of Protein-Coding Genes in Epithelial Cells. PMID:34707609
Nutrient Scarcity in a New Defined Medium Reveals Metabolic Resistance to Antibiotics in the Fish Pathogen Piscirickettsia salmonis. PMID:34707589
Cryptococcus neoformans and Other Opportunistic Cryptococcus Species in Pigeon Dropping in Saudi Arabia: Identification and Characterization by DNA Sequencing. PMID:34707582
Population genomics and evidence of clonal replacement of Plasmodium falciparum in the Peruvian Amazon. PMID:34707204
Symbiosis maintenance in the facultative coral, Oculina arbuscula, relies on nitrogen cycling, cell cycle modulation, and immunity. PMID:34707162
Stage-specific expression of an odorant receptor underlies olfactory behavioral plasticity in Spodoptera littoralis larvae. PMID:34706739
A genome variation map provides insights into the genetics of walnut adaptation and agronomic traits. PMID:34706738
Characterization of M116.1p, a Murine Cytomegalovirus Protein Required for Efficient Infection of Mononuclear Phagocytes. PMID:34705561
Maintenance of genome sequence integrity in long- and short-lived rodent species. PMID:34705500
Selection on ancestral genetic variation fuels repeated ecotype formation in bottlenose dolphins. PMID:34705499
A Protocol for Genome-Wide Analysis of DNA Replication Timing in Intact Root Tips. PMID:34705232
High-quality chromosome-level genome assembly of redlip mullet ( Planiliza haematocheila). PMID:34704426
SARS-CoV-2 variants associated with vaccine breakthrough in the Delaware Valley through summer 2021. PMID:34704098
Spatial-temporal targeted and non-targeted surveys to assess microbiological composition of drinking water in Puerto Rico following Hurricane Maria. PMID:34704006
Characterization of the Testis-specific LINC01016 Gene Reveals Isoform-specific Roles in Controlling Biological Processes. PMID:34703959
Shifts from cis-to trans-splicing of five mitochondrial introns in Tolypanthus maclurei. PMID:34703675
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development. PMID:34702947
Whole-exome sequencing of the mummified remains of Cangrande della Scala (1291-1329 CE) indicates the first known case of late-onset Pompe disease. PMID:34702906
MinION sequencing from sea ice cryoconites leads to de novo genome reconstruction from metagenomes. PMID:34702846
Rhesus macaques self-curing from a schistosome infection can display complete immunity to challenge. PMID:34702841
Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells. PMID:34702373
Life-history traits and habitat availability shape genomic diversity in birds: implications for conservation. PMID:34702080
Speciation in the deep: genomics and morphology reveal a new species of beaked whale Mesoplodon eueu. PMID:34702078
A comparative study of libido in drakes: from phenotypes to molecules. PMID:34700098
Narrow mutational signatures drive acquisition of multidrug resistance in the fungal pathogen Candida glabrata. PMID:34699784
The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling. PMID:34698638
Virophages and retrotransposons colonize the genomes of a heterotrophic flagellate. PMID:34698016
Heterotrophic bacterial diazotrophs are more abundant than their cyanobacterial counterparts in metagenomes covering most of the sunlit ocean. PMID:34697433
Evolutionary history and pan-genome dynamics of strawberry (Fragaria spp.). PMID:34697247
Comparison of PCR versus PCR-Free DNA Library Preparation for Characterising the Human Faecal Virome. PMID:34696523
Viral Decoys: The Only Two Herpesviruses Infecting Invertebrates Evolved Different Transcriptional Strategies to Deflect Post-Transcriptional Editing. PMID:34696401
Genomic Epidemiology of SARS-CoV-2 in Pakistan. PMID:34695600
Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing. PMID:34694871
Highly Parallel Genomic Selection Response in Replicated Drosophila melanogaster Populations with Reduced Genetic Variation. PMID:34694407
Structural variation during dog domestication: insights from gray wolf and dhole genomes. PMID:34694297
Population Structure of Nation-Wide Rice in Thailand. PMID:34693480
Protocol for RNA-seq Expression Analysis in Yeast. PMID:34692911
MINTIA: a metagenomic INserT integrated assembly and annotation tool. PMID:34692239
Convergent adaptation of the genomes of woody plants at the land-sea interface. PMID:34692119
Genomic consequences of population decline in critically endangered pangolins and their demographic histories. PMID:34692098
Understanding divergent domestication traits from the whole-genome sequencing of swamp- and river-buffalo populations. PMID:34692087
eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses. PMID:34691944
Clinical Characteristics of Patients and Whole Genome Sequencing-Based Surveillance of Escherichia coli Community-Onset Bloodstream Infections at a Non-tertiary Hospital in CHINA. PMID:34690998
Phage Selective Pressure Reduces Virulence of Hypervirulent Klebsiella pneumoniae Through Mutation of the wzc Gene. PMID:34690983
Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers. PMID:34689838
Demographic history and divergence of sibling grouse species inferred from whole genome sequencing reveal past effects of climate change. PMID:34689746
Identification of four novel QTL linked to the metabolic syndrome in the Berlin Fat Mouse. PMID:34689180
ARID1A deficiency weakens BRG1-RAD21 interaction that jeopardizes chromatin compactness and drives liver cancer cell metastasis. PMID:34689165
Altered gene expression in slc4a11-/- mouse cornea highlights SLC4A11 roles. PMID:34686736
Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice. PMID:34686347
DREAM represses distinct targets by cooperating with different THAP domain proteins. PMID:34686342
MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data. PMID:34686194
A Novel QTL for Resistance to Phytophthora Crown Rot in Squash. PMID:34685924
Foxd4l1.1 Negatively Regulates Chordin Transcription in Neuroectoderm of Xenopus Gastrula. PMID:34685759
NanoHIV: A Bioinformatics Pipeline for Producing Accurate, Near Full-Length HIV Proviral Genomes Sequenced Using the Oxford Nanopore Technology. PMID:34685559
Characterization of the Radiation Desiccation Response Regulon of the Radioresistant Bacterium Deinococcus radiodurans by Integrative Genomic Analyses. PMID:34685516
Aspergillus Goes Viral: Ecological Insights from the Geographical Distribution of the Mycovirome within an Aspergillus flavus Population and Its Possible Correlation with Aflatoxin Biosynthesis. PMID:34682254
Full Length Transcriptome Highlights the Coordination of Plastid Transcript Processing. PMID:34681956
Unraveling Protein Interactions between the Temperate Virus Bam35 and Its Bacillus Host Using an Integrative Yeast Two Hybrid-High Throughput Sequencing Approach. PMID:34681765
Genome Study of a Novel Virulent Phage vB_SspS_KASIA and Mu-like Prophages of Shewanella sp. M16 Provides Insights into the Genetic Diversity of the Shewanella Virome. PMID:34681734
Mining Fiskeby III and Mandarin (Ottawa) Expression Profiles to Understand Iron Stress Tolerant Responses in Soybean. PMID:34681702
Application of Whole Genome Sequencing to Understand Diversity and Presence of Genes Associated with Sanitizer Tolerance in Listeria monocytogenes from Produce Handling Sources. PMID:34681501
Heritability and De Novo Mutations in Oesophageal Atresia and Tracheoesophageal Fistula Aetiology. PMID:34680991
DBtRend: A Web-Server of tRNA Expression Profiles from Small RNA Sequencing Data in Humans. PMID:34680971
Improved SNV Discovery in Barcode-Stratified scRNA-seq Alignments. PMID:34680953
Against the Odds: Hybrid Zones between Mangrove Killifish Species with Different Mating Systems. PMID:34680881
A DNA Damage Response Gene Panel for Different Histologic Types of Epithelial Ovarian Carcinomas and Their Outcomes. PMID:34680501
OmniSARS2: A Highly Sensitive and Specific RT-qPCR-Based COVID-19 Diagnostic Method Designed to Withstand SARS-CoV-2 Lineage Evolution. PMID:34680431
The Prevalence of Pathogenic or Likely Pathogenic Germline Variants in a Nationwide Cohort of Young Colorectal Cancer Patients Using a Panel of 18 Genes Associated with Colorectal Cancer. PMID:34680242
Complete Genome Sequencing of Field Isolates of Peste des Petits Ruminants Virus from Tanzania Revealed a High Nucleotide Identity with Lineage III PPR Viruses. PMID:34679994
Early-life formula feeding is associated with infant gut microbiota alterations and an increased antibiotic resistance load. PMID:34677583
Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors. PMID:34676924
On the origin and continuing evolution of SARS-CoV-2. PMID:34676127
Whole-Genome Sequencing of Sinocyclocheilus maitianheensis Reveals Phylogenetic Evolution and Immunological Variances in Various Sinocyclocheilus Fishes. PMID:34675964
Genome-Wide Association Mapping Identifies Novel Panicle Morphology Loci and Candidate Genes in Sorghum. PMID:34675951
Whole genome based insights into the phylogeny and evolution of the Juglandaceae. PMID:34674641
Transcriptomic profiling of neonatal mouse granulosa cells reveals new insights into primordial follicle activation†. PMID:34673933
Proximal-end bias from in-vitro reconstituted nucleosomes and the result on downstream data analysis. PMID:34673804
Integrated multi-omics reveals common properties underlying stress granule and P-body formation. PMID:34672913
Comparative Performance of the MGISEQ-2000 and Illumina X-Ten Sequencing Platforms for Paleogenomics. PMID:34671385
Genomic Changes and Genetic Divergence of Vibrio alginolyticus Under Phage Infection Stress Revealed by Whole-Genome Sequencing and Resequencing. PMID:34671325
KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements. PMID:34671158
Comparative evaluation of Nanopore polishing tools for microbial genome assembly and polishing strategies for downstream analysis. PMID:34671046
Population structure, biogeography and transmissibility of Mycobacterium tuberculosis. PMID:34671035
Genomic Profiling of Mycobacterium tuberculosis Strains, Myanmar. PMID:34670644
Brussowvirus SW13 Requires a Cell Surface-Associated Polysaccharide To Recognize Its Streptococcus thermophilus Host. PMID:34669424
Nanopore Genome Sequencing and Variant Analysis of the Susceptible Candida auris Strain L1537/2020, Salvador, Brazil. PMID:34669105
Flavonoid deficiency disrupts redox homeostasis and terpenoid biosynthesis in glandular trichomes of tomato. PMID:34668550
Sequence features of retrotransposons allow for epigenetic variability. PMID:34668484
The genome-wide rate and spectrum of EMS-induced heritable mutations in the microcrustacean Daphnia: on the prospect of forward genetics. PMID:34667306
Pseudomonas aeruginosa transcriptome adaptations from colonization to biofilm infection of skin wounds. PMID:34667187
Transcription and splicing dynamics during early Drosophila development. PMID:34667107
PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands. PMID:34667079
The BORDER family of negative transcription elongation factors regulates flowering time in Arabidopsis. PMID:34666004
Translational repression of NMD targets by GIGYF2 and EIF4E2. PMID:34665823
Emergence of novel strains of Shigella flexneri associated with sexual transmission in adult men in England, 2019-2020. PMID:34665107
Distinction of lymphoid and myeloid clonal hematopoiesis. PMID:34663986
Probiotic consumption influences universal adaptive mutations in indigenous human and mouse gut microbiota. PMID:34663913
Functional recovery of the germ line following splicing collapse. PMID:34663906
HERVH-derived lncRNAs negatively regulate chromatin targeting and remodeling mediated by CHD7. PMID:34663690
Differential enrichment of H3K9me3 at annotated satellite DNA repeats in human cell lines and during fetal development in mouse. PMID:34663449
DNA methylation-calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation. PMID:34663425
Positive Selection and Horizontal Gene Transfer in the Genome of a Male-Killing Wolbachia. PMID:34662426
Genome-wide analysis of deletions in maize population reveals abundant genetic diversity and functional impact. PMID:34661697
Establishment of a near-contiguous genome sequence of the citric acid producing yeast Yarrowia lipolytica DSM 3286 with resolution of rDNA clusters and telomeres. PMID:34661101
Data of RNA-seq transcriptomes in the brain associated with aggression in males of the fish Betta splendens. PMID:34660862
RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days. PMID:34660856
Development and Dynamics of Cytomegalovirus UL97 Ganciclovir Resistance Mutations in Transplant Recipients Detected by Next-Generation Sequencing. PMID:34660835
Panobinostat Effectively Increases Histone Acetylation and Alters Chromatin Accessibility Landscape in Canine Embryonic Fibroblasts but Does Not Enhance Cellular Reprogramming. PMID:34660761
Comprehensive Genomic Characterization Analysis Identifies an Oncogenic Pseudogene RP11-3543B.1 in Human Gastric Cancer. PMID:34660601
Identification and Validation of High LD Hotspot Genomic Regions Harboring Stem Rust Resistant Genes on 1B, 2A (Sr38), and 7B Chromosomes in Wheat. PMID:34659366
Genome-Wide Association Mapping of Late Blight Tolerance Trait in Potato (Solanum tuberosum L.). PMID:34659338
High-Quality Genome of the Medicinal Plant Strobilanthes cusia Provides Insights Into the Biosynthesis of Indole Alkaloids. PMID:34659312
MKK4/5-MPK3/6 Cascade Regulates Agrobacterium-Mediated Transformation by Modulating Plant Immunity in Arabidopsis. PMID:34659297
Genome Sequence Analysis of Clostridium chauvoei Strains of European Origin and Evaluation of Typing Options for Outbreak Investigations. PMID:34659160
Combinatorial patterns of gene expression changes contribute to variable expressivity of the developmental delay-associated 16p12.1 deletion. PMID:34657631
Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair. PMID:34655526
Genome sequencing of turmeric provides evolutionary insights into its medicinal properties. PMID:34654884
Hierarchical genetic structure and implications for conservation of the world's largest salmonid, Hucho taimen. PMID:34654859
Comparative analysis of full-length mitochondrial genomes of five Skeletonema species reveals conserved genome organization and recent speciation. PMID:34654361
Ssl2/TFIIH function in transcription start site scanning by RNA polymerase II in Saccharomyces cerevisiae. PMID:34652274
Pneumonia Patients Caused by Co-infection With SARS-CoV-2 and Human Adenovirus in China. PMID:34650998
RNA Sequencing Data for FFPE Tumor Blocks Can Be Used for Robust Estimation of Tumor Mutation Burden in Individual Biosamples. PMID:34650919
A photoregulatory mechanism of the circadian clock in Arabidopsis. PMID:34650267
E. coli aggregation and impaired cell division after terahertz irradiation. PMID:34650158
Direct genome-wide identification of G-quadruplex structures by whole-genome resequencing. PMID:34650044
A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation. PMID:34649616
Cultivation of common bacterial species and strains from human skin, oral, and gut microbiota. PMID:34649516
Transcriptional expression changes during compensatory plasticity in the terminal ganglion of the adult cricket Gryllus bimaculatus. PMID:34649498
Hallstatt miners consumed blue cheese and beer during the Iron Age and retained a non-Westernized gut microbiome until the Baroque period. PMID:34648730
Genetic diversity of Salmonella Paratyphi A isolated from enteric fever patients in Bangladesh from 2008 to 2018. PMID:34648506
Segmentation and genome annotation algorithms for identifying chromatin state and other genomic patterns. PMID:34648491
Characterization of a pESI-like plasmid and analysis of multidrug-resistant Salmonella enterica Infantis isolates in England and Wales. PMID:34647862
Chromosome-Scale Assembly of the Complete Genome Sequence of Porcisia hertigi, Isolate C119, Strain LV43. PMID:34647802
Introduction of SARS-CoV-2 C.37 (WHO VOI lambda) in the Sao Paulo State, Southeast Brazil. PMID:34647634
Genome features of common vetch (Vicia sativa) in natural habitats. PMID:34646975
Genome-wide analysis reveals demographic and life-history patterns associated with habitat modification in landlocked, deep-spawning sockeye salmon (Oncorhynchus nerka). PMID:34646462
Characterization of FMR1 Repeat Expansion and Intragenic Variants by Indirect Sequence Capture. PMID:34646309
Oestrogen engages brain MC4R signalling to drive physical activity in female mice. PMID:34646010
Genomic prediction for testes weight of the tiger pufferfish, Takifugu rubripes, using medium to low density SNPs. PMID:34645956
Gene.iobio: an interactive web tool for versatile, clinically-driven variant interrogation and prioritization. PMID:34645894
RNA-seq of peripheral blood mononuclear cells of congenital generalized lipodystrophy type 2 patients. PMID:34645804
Microbial colonization and resistome dynamics in food processing environments of a newly opened pork cutting industry during 1.5 years of activity. PMID:34645520
TIGER: The gene expression regulatory variation landscape of human pancreatic islets. PMID:34644572
Genomic surveillance of SARS-CoV-2 tracks early interstate transmission of P.1 lineage and diversification within P.2 clade in Brazil. PMID:34644287
Exposure to ionizing radiation disrupts normal epigenetic aging in Japanese medaka. PMID:34644261
Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer. PMID:34644115
The genetics of vigour-related traits in chickpea (Cicer arietinum L.): insights from genomic data. PMID:34643761
scAPAatlas: an atlas of alternative polyadenylation across cell types in human and mouse. PMID:34643729
RGD v2.0: a major update of the ruminant functional and evolutionary genomics database. PMID:34643708
Simplifying the development of portable, scalable, and reproducible workflows. PMID:34643507
Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development. PMID:34643182
Intra-host evolution during SARS-CoV-2 prolonged infection. PMID:34642605
Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes. PMID:34642339
Estimation of cell-free fetal DNA fraction from maternal plasma based on linkage disequilibrium information. PMID:34642337
Recovery of strain-resolved genomes from human microbiome through an integration framework of single-cell genomics and metagenomics. PMID:34641955
Genomic analysis of distinct bleaching tolerances among cryptic coral species. PMID:34641729
Utilization of Whole Exome Sequencing in Non-Syndromic Premature Ovarian Failure: Ficolin-3 Gene Mutation in an Iranian Family. PMID:34641644
Road to Metastasis: The TWEAK Pathway as a Discriminant between Metastasizing and Non-Metastasizing Thick Melanomas. PMID:34638912
Platelet-Released Growth Factors Induce Genes Involved in Extracellular Matrix Formation in Human Fibroblasts. PMID:34638874
Multiple Variant Calling Pipelines in Wheat Whole Exome Sequencing. PMID:34638743
Evaluating the Bioenergetics Health Index Ratio in Leigh Syndrome Fibroblasts to Understand Disease Severity. PMID:34638685
Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models. PMID:34638546
Nucleolin Aptamer N6L Reprograms the Translational Machinery and Acts Synergistically with mTORi to Inhibit Pancreatic Cancer Proliferation. PMID:34638443
Targeted Sequencing Revealed Distinct Mutational Profiles of Ocular and Extraocular Sebaceous Carcinomas. PMID:34638295
Chromosome-specific polymorphic SSR markers in tropical eucalypt species using low coverage whole genome sequences: systematic characterization and validation. PMID:34638180
Simultaneous profiling of multiple chromatin proteins in the same cells. PMID:34637755
NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain. PMID:34637754
A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells. PMID:34637753
Persistence of infectious SARS-CoV-2 particles for up to 37 days in patients with mild COVID-19. PMID:34637150
Autopolyploidization affects transcript patterns and gene targeting frequencies in Physcomitrella. PMID:34636965
Diverse phosphate and auxin transport loci distinguish phosphate tolerant from sensitive Arabidopsis accessions. PMID:34636851
Exploring the Meta-regulon of the CRP/FNR Family of Global Transcriptional Regulators in a Partial-Nitritation Anammox Microbiome. PMID:34636676
Transcriptomics Reveals the Putative Mycoparasitic Strategy of the Mushroom Entoloma abortivum on Species of the Mushroom Genus Armillaria. PMID:34636668
Expanding the Staphylococcus aureus SarA Regulon to Small RNAs. PMID:34636666
Whole-exome sequencing identified first homozygous frameshift variant in the COLEC10 gene in an Iranian patient causing 3MC syndrome type 3. PMID:34636477
The population genomic structure of green turtles (Chelonia mydas) suggests a warm-water corridor for tropical marine fauna between the Atlantic and Indian oceans during the last interglacial. PMID:34635850
Three chromosome-level duck genome assemblies provide insights into genomic variation during domestication. PMID:34635656
The genetic impact of an Ebola outbreak on a wild gorilla population. PMID:34635054
Metabolic gene regulation by Drosophila GATA transcription factor Grain. PMID:34634038
Selective sorting of ancestral introgression in maize and teosinte along an elevational cline. PMID:34634032
Nucleotide variation in the phytoene synthase (ClPsy1) gene contributes to golden flesh in watermelon (Citrullus lanatus L.). PMID:34633472
Evolutionary Implications of the RNA N6-Methyladenosine Methylome in Plants. PMID:34633447
Global approaches for profiling transcription initiation. PMID:34632443
Amplification of Femtograms of Bacterial DNA Within 3 h Using a Digital Microfluidics Platform for MinION Sequencing. PMID:34632220
Chytridiomycosis Outbreak in a Chilean Giant Frog (Calyptocephalella gayi) Captive Breeding Program: Genomic Characterization and Pathological Findings. PMID:34631859
Case Report: Whole-Exome Sequencing of Hypothalamic Hamartoma From an Infant With Pallister-Hall Syndrome Revealed Novel de novo Mutation in the GLI3. PMID:34631784
Interaction Between Functionally Activate Endometrial Microbiota and Host Gene Regulation in Endometrial Cancer. PMID:34631710
Transfer RNA-derived non-coding RNAs (tncRNAs): Hidden regulation of plants' transcriptional regulatory circuits. PMID:34630945
Development of Genome-Wide Functional Markers Using Draft Genome Assembly of Guava (Psidium guajava L.) cv. Allahabad Safeda to Expedite Molecular Breeding. PMID:34630458
In vivo Selection of Imipenem Resistance Among Ceftazidime-Avibactam-Resistant, Imipenem-Susceptible Klebsiella pneumoniae Isolate With KPC-33 Carbapenemase. PMID:34630354
Genome-wide association study for candidate genes controlling seed yield and its components in rapeseed (Brassica napus subsp. napus). PMID:34629771
Comparison of sequencing data processing pipelines and application to underrepresented African human populations. PMID:34627144
Comparative single-cell analysis of biopsies clarifies pathogenic mechanisms in Klinefelter syndrome. PMID:34626582
Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability. PMID:34626567
Detecting cryptic clinically relevant structural variation in exome-sequencing data increases diagnostic yield for developmental disorders. PMID:34626536
Metagenomic sequencing determines complete infectious bronchitis virus (avian Gammacoronavirus) vaccine strain genomes and associated viromes in chicken clinical samples. PMID:34626348
Testis transcriptome profiling identified lncRNAs involved in spermatogenic arrest of cattleyak. PMID:34626308
BRAF mutations may identify a clinically distinct subset of glioblastoma. PMID:34625582
Concordance analysis of microsatellite instability status between polymerase chain reaction based testing and next generation sequencing for solid tumors. PMID:34625576
Population genomics provides insights into the population structure and temperature-driven adaptation of Collichthys lucidus. PMID:34625022
Transcriptional and functional divergence in lateral hypothalamic glutamate neurons projecting to the lateral habenula and ventral tegmental area. PMID:34624220
PASTA kinase-dependent control of peptidoglycan synthesis via ReoM is required for cell wall stress responses, cytosolic survival, and virulence in Listeria monocytogenes. PMID:34624065
Genome-Wide Analysis of Cadmium-Induced, Germline Mutations in a Long-Term Daphnia pulex Mutation-Accumulation Experiment. PMID:34623885
Identification of Faecalibacterium prausnitzii strains for gut microbiome-based intervention in Alzheimer's-type dementia. PMID:34622235
An international virtual hackathon to build tools for the analysis of structural variants within species ranging from coronaviruses to vertebrates. PMID:34621504
A chromosome-level genome sequence of Chrysanthemum seticuspe, a model species for hexaploid cultivated chrysanthemum. PMID:34620992
The mitochondrial genome and Epigenome of the Golden lion Tamarin from fecal DNA using Nanopore adaptive sequencing. PMID:34620074
Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease. PMID:34619744
Ribosome profiling elucidates differential gene expression in bundle sheath and mesophyll cells in maize. PMID:34618144
Genome- and transcriptome-wide off-target analyses of an improved cytosine base editor. PMID:34618139
iRegNet: an integrative Regulatory Network analysis tool for Arabidopsis thaliana. PMID:34618085
CYCLIC NUCLEOTIDE-GATED ION CHANNEL 2 modulates auxin homeostasis and signaling. PMID:34618044
Complex species and strain ecology of the vaginal microbiome from pregnancy to postpartum and association with preterm birth. PMID:34617072
Pig genome functional annotation enhances the biological interpretation of complex traits and human disease. PMID:34615879
Genomic insight into balancing high yield, good quality, and blast resistance of japonica rice. PMID:34615543
Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization. PMID:34615539
Comparative transcriptomic analysis reveals gene regulation mediated by caspase activity in a chordate organism. PMID:34615460
metaGEM: reconstruction of genome scale metabolic models directly from metagenomes. PMID:34614189
A replication-linked mutational gradient drives somatic mutation accumulation and influences germline polymorphisms and genome composition in mitochondrial DNA. PMID:34614167
Genomic Stability and Phenotypic Characteristics of Industrially Produced Lacticaseibacillus rhamnosus GG in a Yogurt Matrix. PMID:34613788
Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition. PMID:34613786
Chromosome-level genome assembly reveals homologous chromosomes and recombination in asexual rotifer Adineta vaga. PMID:34613768
Metagenomic and Metatranscriptomic Characterization of a Microbial Community That Catalyzes Both Energy-Generating and Energy-Storing Electrode Reactions. PMID:34613754
Interplay between Bacterial Clones and Plasmids in the Spread of Antibiotic Resistance Genes in the Gut: Lessons from a Temporal Study in Veal Calves. PMID:34613750
Prediction of antimicrobial resistance based on whole-genome sequencing and machine learning. PMID:34613360
Upregulation of Human Endogenous Retroviruses in Bronchoalveolar Lavage Fluid of COVID-19 Patients. PMID:34612698
Adjunctive Probiotics Alleviates Asthmatic Symptoms via Modulating the Gut Microbiome and Serum Metabolome. PMID:34612663
Microbiome signature and diversity regulates the level of energy production under anaerobic condition. PMID:34611238
CHD1 controls H3.3 incorporation in adult brain chromatin to maintain metabolic homeostasis and normal lifespan. PMID:34610319
PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation. PMID:34610311
c-FOS drives reversible basal to squamous cell carcinoma transition. PMID:34610301
Detection of whole genome selection signatures of Pakistani Teddy goat. PMID:34609690
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation. PMID:34609283
A sex-specific evolutionary interaction between ADCY9 and CETP. PMID:34609279
Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis. PMID:34609164
SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment. PMID:34608315
Interaction of Male Specific Lethal complex and genomic imbalance on global gene expression in Drosophila. PMID:34608252
Gitelman-Like Syndrome Caused by Pathogenic Variants in mtDNA. PMID:34607911
A standard knockout procedure alters expression of adjacent loci at the translational level. PMID:34606617
Phylogenetic systematics of Butyrivibrio and Pseudobutyrivibrio genomes illustrate vast taxonomic diversity, open genomes and an abundance of carbohydrate-active enzyme family isoforms. PMID:34605764
Parallel functional testing identifies enhancers active in early postnatal mouse brain. PMID:34605404
Patient-Derived Organoids Can Guide Personalized-Therapies for Patients with Advanced Breast Cancer. PMID:34605222
Epistasis, aneuploidy, and functional mutations underlie evolution of resistance to induced microtubule depolymerization. PMID:34605051
Association of Asthma and Rhinitis with Epigenetics of Coronavirus Related Genes. PMID:34604700
Transcriptome Analysis of Effects of Folic Acid Supplement on Gene Expression in Liver of Broiler Chickens. PMID:34604366
High Throughput Transcriptome Data Analysis and Computational Verification Reveal Immunotherapy Biomarkers of Compound Kushen Injection for Treating Triple-Negative Breast Cancer. PMID:34604090
The heterogeneity among subgroups of haplogroup J influencing Alzheimer's disease risk. PMID:34603783
Population structure, gene flow, and sex-biased dispersal in the reticulated flatwoods salamander (Ambystoma bishopi): Implications for translocations. PMID:34603495
Evidence of stock connectivity, hybridization, and misidentification in white anglerfish supports the need of a genetics-informed fisheries management framework. PMID:34603494
High-Quality de novo Chromosome-Level Genome Assembly of a Single Bombyx mori With BmNPV Resistance by a Combination of PacBio Long-Read Sequencing, Illumina Short-Read Sequencing, and Hi-C Sequencing. PMID:34603381
Inhibition of Granuloma Triglyceride Synthesis Imparts Control of Mycobacterium tuberculosis Through Curtailed Inflammatory Responses. PMID:34603294
Genome of Ganoderma Species Provides Insights Into the Evolution, Conifers Substrate Utilization, and Terpene Synthesis for Ganoderma tsugae. PMID:34603250
Variable heat shock response in Antarctic biofouling serpulid worms. PMID:34601709
Multivalent poultry vaccine development using Protein Glycan Coupling Technology. PMID:34600535
Neurogenomic divergence during speciation by reinforcement of mating behaviors in chorus frogs (Pseudacris). PMID:34600496
SamQL: a structured query language and filtering tool for the SAM/BAM file format. PMID:34600480
Metagenomic investigation of potential abortigenic pathogens in foetal tissues from Australian horses. PMID:34600470
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice. PMID:34599880
A Minimally Morphologically Destructive Approach for DNA Retrieval and Whole-Genome Shotgun Sequencing of Pinned Historic Dipteran Vector Species. PMID:34599327
Productive visualization of high-throughput sequencing data using the SeqCode open portable platform. PMID:34599234
Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASR complex in mouse models. PMID:34599184
Indication-specific tumor evolution and its impact on neoantigen targeting and biomarkers for individualized cancer immunotherapies. PMID:34599029
Genomic analysis of the nomenclatural type strain of the nematode-associated entomopathogenic bacterium Providencia vermicola. PMID:34598677
Dietary, Cultural, and Pathogens-Related Selective Pressures Shaped Differential Adaptive Evolution among Native Mexican Populations. PMID:34597392
Gosling: A Grammar-based Toolkit for Scalable and Interactive Genomics Data Visualization. PMID:34596551
Brief Protocol for EDGE Bioinformatics: Analyzing Microbial and Metagenomic NGS Data. PMID:34595290
Genomic Evidence That Governmentally Produced Cannabis sativa Poorly Represents Genetic Variation Available in State Markets. PMID:34594346
A differential DNA methylome signature of pulmonary immune cells from individuals converting to latent tuberculosis infection. PMID:34593857
Chromosome-level genome assemblies of five Prunus species and genome-wide association studies for key agronomic traits in peach. PMID:34593767
A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas. PMID:34593527
Metagenomic analysis of ancient dental calculus reveals unexplored diversity of oral archaeal Methanobrevibacter. PMID:34593021
The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching. PMID:34592986
Gene Expression Nebulas (GEN): a comprehensive data portal integrating transcriptomic profiles across multiple species at both bulk and single-cell levels. PMID:34591957
Draft Genome Sequences of 12 Clostridium tyrobutyricum Strains Isolated from Raw Milk and Cheese. PMID:34591680
Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) sp. Ghana, Isolate GH5, Strain LV757. PMID:34591664
Metagenomic Analysis of Biochemical Passive Reactors During Acid Mine Drainage Bioremediation Reveals Key Co-selected Metabolic Functions. PMID:34591135
Principles of mRNA targeting via the Arabidopsis m6A-binding protein ECT2. PMID:34591015
Identification of potential pathogenic mutations in Chinese children with first branchial cleft anomalies detected by whole-exome sequencing. PMID:34589676
Whole Genome Sequence-Based Identification of Clostridium estertheticum Complex Strains Supports the Need for Taxonomic Reclassification Within the Species Clostridium estertheticum. PMID:34589074
Functional Characterization of the Cell Division Gene Cluster of the Wall-less Bacterium Mycoplasma genitalium. PMID:34589065
Global Expansion of Linezolid-Resistant Coagulase-Negative Staphylococci. PMID:34589061
Development of a multi-species SNP array for serrasalmid fish Colossoma macropomum and Piaractus mesopotamicus. PMID:34588599
Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9. PMID:34588447
Ecogenomics Reveals Microbial Metabolic Networks in a Psychrophilic Methanogenic Bioreactor Treating Soy Sauce Production Wastewater. PMID:34588388
High Prevalence of Coinfecting Enteropathogens in Suspected Rotavirus Vaccine Breakthrough Cases. PMID:34586890
Dose-Dependent Response to Infection with Ebola Virus in the Ferret Model and Evidence of Viral Evolution in the Eye. PMID:34586862
MustSeq, an alternative approach for multiplexible strand-specific 3' end sequencing of mRNA transcriptome confers high efficiency and practicality. PMID:34586036
Novel Daptomycin Tolerance and Resistance Mutations in Methicillin-Resistant Staphylococcus aureus from Adaptive Laboratory Evolution. PMID:34585959
A homozygous R148W mutation in Semaphorin 7A causes progressive familial intrahepatic cholestasis. PMID:34585848
Examining the Developmental Trajectory of an in Vitro Model of Mouse Primordial Germ Cells following Exposure to Environmentally Relevant Bisphenol A Levels. PMID:34585602
Ciprofloxacin induced antibiotic resistance in Salmonella Typhimurium mutants and genome analysis. PMID:34585273
Analytical protocol to identify local ancestry-associated molecular features in cancer. PMID:34585150
Genome-wide autosomal, mtDNA, and Y chromosome analysis of King Bela III of the Hungarian Arpad dynasty. PMID:34584164
Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development. PMID:34584102
rKOMICS: an R package for processing mitochondrial minicircle assemblies in population-scale genome projects. PMID:34583651
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. PMID:34582804
An integrated approach to identify environmental modulators of genetic risk factors for complex traits. PMID:34582792
Chemical capping improves template switching and enhances sequencing of small RNAs. PMID:34581823
Amplicon Remodeling and Genomic Mutations Drive Population Dynamics after Segmental Amplification. PMID:34581806
Androgen-Binding Protein (Abp) Evolutionary History: Has Positive Selection Caused Fixation of Different Paralogs in Different Taxa of the Genus Mus? PMID:34581786
Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants. PMID:34581669
BiG-MAP: an Automated Pipeline To Profile Metabolic Gene Cluster Abundance and Expression in Microbiomes. PMID:34581602
MLL3 is a de novo cause of endocrine therapy resistance. PMID:34581028
A role for arthropods as vectors of multidrug-resistant Enterobacterales in surgical site infections from South Asia. PMID:34580444
Genomic stability among O3:K6 V. parahaemolyticus pandemic strains isolated between 1996 to 2012 in American countries. PMID:34579653
Genetic Loci Associated with Resistance to Zucchini Yellow Mosaic Virus in Squash. PMID:34579467
Patterns of Coevolutionary Adaptations across Time and Space in Mouse Gammaretroviruses and Three Restrictive Host Factors. PMID:34578445
High Rate of Mutational Events in SARS-CoV-2 Genomes across Brazilian Geographical Regions, February 2020 to June 2021. PMID:34578387
Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection. PMID:34578309
Identification and Full Characterisation of Two Novel Crustacean Infecting Members of the Family Nudiviridae Provides Support for Two Subfamilies. PMID:34578276
The Influence of Habitat on Viral Diversity in Neotropical Rodent Hosts. PMID:34578272
Monitoring Natural SARS-CoV-2 Infection in Lions (Panthera leo) at the Barcelona Zoo: Viral Dynamics and Host Responses. PMID:34578266
Fifty Generations of Amitosis: Tracing Asymmetric Allele Segregation in Polyploid Cells with Single-Cell DNA Sequencing. PMID:34576874
Microbiota of Cow's Milk with Udder Pathologies. PMID:34576870
Genome-Resolved Meta-Analysis of the Microbiome in Oil Reservoirs Worldwide. PMID:34576708
Discriminating Clonotypes of Influenza A Virus Genes by Nanopore Sequencing. PMID:34576230
Alternative Splicing Regulation of Low-Frequency Genetic Variants in Exon 2 of TREM2 in Alzheimer's Disease by Splicing-Based Aggregation. PMID:34576031
Early Embryo Exposure to Assisted Reproductive Manipulation Induced Subtle Changes in Liver Epigenetics with No Apparent Negative Health Consequences in Rabbit. PMID:34575877
Computational Methods to Study Human Transcript Variants in COVID-19 Infected Lung Cancer Cells. PMID:34575842
Genomic Evidence for Rare Hybridization and Large Demographic Changes in the Evolutionary Histories of Four North American Dove Species. PMID:34573643
Domestication Explains Two-Thirds of Differential-Gene-Expression Variance between Domestic and Wild Animals; The Remaining One-Third Reflects Intraspecific and Interspecific Variation. PMID:34573632
Whole-Genome Profiles of Malay Colorectal Cancer Patients with Intact MMR Proteins. PMID:34573430
Breeding Tomato Hybrids for Flavour: Comparison of GWAS Results Obtained on Lines and F1 Hybrids. PMID:34573425
Environmental Influences Measured by Epigenetic Clock and Vulnerability Components at Birth Impact Clinical ASD Heterogeneity. PMID:34573415
Genetic Diversity in Casein Gene Cluster in a Dromedary Camel (C. dromedarius) Population from the United Arab Emirates. PMID:34573399
Common and Unique Genetic Background between Attention-Deficit/Hyperactivity Disorder and Excessive Body Weight. PMID:34573389
Gene Annotation and Transcriptome Delineation on a De Novo Genome Assembly for the Reference Leishmania major Friedlin Strain. PMID:34573340
Chromosome-Level Genome Assemblies Expand Capabilities of Genomics for Conservation Biology. PMID:34573318
Substitutions in SurA and BamA Lead to Reduced Susceptibility to Broad Range Antibiotics in Gonococci. PMID:34573293
Comparative Transcriptome Analysis of the Expression of Antioxidant and Immunity Genes in the Spleen of a Cyanidin 3-O-Glucoside-Treated Alzheimer's Mouse Model. PMID:34573067
Selenoprotein T Protects Endothelial Cells against Lipopolysaccharide-Induced Activation and Apoptosis. PMID:34573059
Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea. PMID:34572983
Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes. PMID:34572750
Colistin and Carbapenem-Resistant Acinetobacter baumannii Aci46 in Thailand: Genome Analysis and Antibiotic Resistance Profiling. PMID:34572636
Retinoic Acid Receptors and the Control of Positional Information in the Regenerating Axolotl Limb. PMID:34571821
Bioinformatics and Machine Learning Approaches to Understand the Regulation of Mobile Genetic Elements. PMID:34571773
Intersex Plays a Role in Microbial Homeostasis in the Brown Planthopper. PMID:34571752
Distinct gene-set burden patterns underlie common generalized and focal epilepsies. PMID:34571366
Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different. PMID:34570834
Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates. PMID:34570776
A biallelic SNIP1 Amish founder variant causes a recognizable neurodevelopmental disorder. PMID:34570759
A vast pool of lineage-specific microproteins encoded by long non-coding RNAs in plants. PMID:34570232
SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation. PMID:34569685
RNA polymerase II clusters form in line with surface condensation on regulatory chromatin. PMID:34569155
The genetics of gene expression in a Caenorhabditis elegans multiparental recombinant inbred line population. PMID:34568931
A candidate chromosome inversion in Arctic charr (Salvelinus alpinus) identified by population genetic analysis techniques. PMID:34568922
Improved draft reference genome for the Glassy-winged Sharpshooter (Homalodisca vitripennis), a vector for Pierce's disease. PMID:34568917
Whole-genome variation of transposable element insertions in a maize diversity panel. PMID:34568911
Genetic and functional analysis reveals TENM4 contributes to schizophrenia. PMID:34568788
Variation in type two taste receptor genes is associated with bitter tasting phenylthiocarbamide consumption in mature Targhee and Rambouillet rams. PMID:34568769
Fha Deficient Bordetella pertussis Isolates in Iran with 50 Years Whole Cell Pertussis Vaccination. PMID:34568185
VGEA: an RNA viral assembly toolkit. PMID:34567846
Analyses of open-access multi-omics data sets reveal genetic and expression characteristics of maize ZmCCT family genes. PMID:34567492
Identification of Quantitative Trait Loci Controlling the Development of Prickles in Eggplant by Genome Re-sequencing Analysis. PMID:34567042
Characterization of Shiga Toxin 2a Encoding Bacteriophages Isolated From High-Virulent O145:H25 Shiga Toxin-Producing Escherichia coli. PMID:34566932
Functional Mapping of Phenotypic Plasticity of Staphylococcus aureus Under Vancomycin Pressure. PMID:34566908
Improved library preparation protocols for amplicon sequencing-based noninvasive fetal genotyping for RHD-positive D antigen-negative alleles. PMID:34565457
Histone H3 lysine 27 acetylation profile undergoes two global shifts in undernourished children and suggests altered one-carbon metabolism. PMID:34565452
Revealing the coexistence of differentiation and communication in an endemic hare, Lepus yarkandensis (Mammalia, Leporidae) using specific-length amplified fragment sequencing. PMID:34565397
Precise Characterization of Bombyx mori Fibroin Heavy Chain Gene Using Cpf1-Based Enrichment and Oxford Nanopore Technologies. PMID:34564273
Epitranscriptomics modifier pentostatin indirectly triggers Toll-like receptor 3 and can enhance immune infiltration in tumors. PMID:34563676
The taxonomic distribution of histamine-secreting bacteria in the human gut microbiome. PMID:34563136
Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes. PMID:34563126
The branchless gene Clbl in watermelon encoding a TERMINAL FLOWER 1 protein regulates the number of lateral branches. PMID:34562124
Somatic Mutation Analysis in Salix suchowensis Reveals Early-Segregated Cell Lineages. PMID:34562099
Vulcan: Improved long-read mapping and structural variant calling via dual-mode alignment. PMID:34561697
High-throughput RNA sequencing of paraformaldehyde-fixed single cells. PMID:34561439
Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung. PMID:34561242
Reduced B12 uptake and increased gastrointestinal formate are associated with archaeome-mediated breath methane emission in humans. PMID:34560884
Ancient genomes reveal long-range influence of the pre-Columbian culture and site of Tiwanaku. PMID:34559567
Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor. PMID:34559564
A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance. PMID:34559558
High-resolution breakpoint junction mapping of proximally extended D4Z4 deletions in FSHD1 reveals evidence for a founder effect. PMID:34559225
Resequencing of 301 ramie accessions identifies genetic loci and breeding selection for fibre yield traits. PMID:34558775
Early Leukocyte Responses in Ex-Vivo Models of Healing and Non-Healing Human Leishmania (Viannia) panamensis Infections. PMID:34557423
Multidrug-Resistant Lineage of Enterotoxigenic Escherichia coli ST182 With Serotype O169:H41 in Airline Waste. PMID:34557175
The complete genome of 2,6-dichlorobenzamide (BAM) degrader Aminobacter sp. MSH1 suggests a polyploid chromosome, phylogenetic reassignment, and functions of plasmids. PMID:34556718
Periodontitis associates with species-specific gene expression of the oral microbiota. PMID:34556654
NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis. PMID:34555356
Coupling of spliceosome complexity to intron diversity. PMID:34555349
Vegan vs. omnivore diets paradox: A whole-metagenomic approach for defining metabolic networks during the race in ultra-marathoners- a before and after study design. PMID:34555041
Drug resistance in diploid yeast is acquired through dominant alleles, haploinsufficiency, gene duplication and aneuploidy. PMID:34555030
Protein-coding repeat polymorphisms strongly shape diverse human phenotypes. PMID:34554798
Examination of Gene Loss in the DNA Mismatch Repair Pathway and Its Mutational Consequences in a Fungal Phylum. PMID:34554246
Whole-Genome Sequences of SARS-CoV-2 Isolates from Ethiopian Patients. PMID:34554000
Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design. PMID:34553212
The role of metadata in reproducible computational research. PMID:34553169
Updated Genome Assembly of Bighead Carp (Hypophthalmichthys nobilis) and Its Differences Between Male and Female on Genomic, Transcriptomic, and Methylation Level. PMID:34552623
Discovery of Novel Viruses Associated With the Invasive Cane Toad (Rhinella marina) in Its Native and Introduced Ranges. PMID:34552575
SCReadCounts: estimation of cell-level SNVs expression from scRNA-seq data. PMID:34551708
RNALocate v2.0: an updated resource for RNA subcellular localization with increased coverage and annotation. PMID:34551440
Genomic impact of stress-induced transposable element mobility in Arabidopsis. PMID:34551439
Animal-eRNAdb: a comprehensive animal enhancer RNA database. PMID:34551433
Prophage Tracer: precisely tracing prophages in prokaryotic genomes using overlapping split-read alignment. PMID:34551431
High resolution copy number inference in cancer using short-molecule nanopore sequencing. PMID:34551429
SNP prioritization in targeted sequencing data associated with humoral immune responses in chicken. PMID:34551372
Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia. PMID:34551306
rs41291957 controls miR-143 and miR-145 expression and impacts coronary artery disease risk. PMID:34551209
In silico analysis enabling informed design for genome editing in medicinal cannabis; gene families and variant characterisation. PMID:34551006
RNA Viromics of Southern California Wastewater and Detection of SARS-CoV-2 Single-Nucleotide Variants. PMID:34550753
Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms. PMID:34550736
Segregational Drift Constrains the Evolutionary Rate of Prokaryotic Plasmids. PMID:34550379
Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections. PMID:34550348
Genome-wide analysis provides a deeper understanding of the population structure of the Salmonella enterica serotype Paratyphi B complex in Bangladesh. PMID:34550065
The Mycobacterium tuberculosis sRNA F6 Modifies Expression of Essential Chaperonins, GroEL2 and GroES. PMID:34549992
Global multi-environment resistance QTL for foliar late blight resistance in tetraploid potato with tropical adaptation. PMID:34549785
The Gossypium anomalum genome as a resource for cotton improvement and evolutionary analysis of hybrid incompatibility. PMID:34549783
Complete genome sequencing and molecular characterization of SARS-COV-2 from COVID-19 cases in Alborz province in Iran. PMID:34549097
Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism. PMID:34548527
Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model. PMID:34548081
Chromatin accessibility and regulatory vocabulary across indicine cattle tissues. PMID:34548076
Genome sequencing of the neotype strain CBS 554.65 reveals the MAT1-2 locus of Aspergillus niger. PMID:34548025
Transitions to asexuality and evolution of gene expression in Artemia brine shrimp. PMID:34547909
piRNA-independent transposon silencing by the Drosophila THO complex. PMID:34547226
A chromosome-scale genome assembly and karyotype of the ctenophore Hormiphora californensis. PMID:34545398
Confirmation of Oryctes rhinoceros nudivirus infections in G-haplotype coconut rhinoceros beetles (Oryctes rhinoceros) from Palauan PCR-positive populations. PMID:34545119
Orthogonal genome-wide screens of bat cells identify MTHFD1 as a target of broad antiviral therapy. PMID:34544865
Efficient construction of a linkage map and haplotypes for Mentha suaveolens using sequence capture. PMID:34544134
Whole-genome sequencing of multiple isolates of Puccinia triticina reveals asexual lineages evolving by recurrent mutations. PMID:34544127
Chromosome-level genome assembly of the blue crab, Callinectes sapidus. PMID:34544121
The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands. PMID:34543350
Biomedical Data Commons (BMDC) prioritizes B-lymphocyte non-coding genetic variants in Type 1 Diabetes. PMID:34543288
Avian Neo-Sex Chromosomes Reveal Dynamics of Recombination Suppression and W Degeneration. PMID:34542640
Genomic signatures of inbreeding in a critically endangered parrot, the kākāpō. PMID:34542587
Allele-specific assembly of a eukaryotic genome corrects apparent frameshifts and reveals a lack of nonsense-mediated mRNA decay. PMID:34541528
Rapid Enabling of Gluconobacter oxydans Resistance to High D-Sorbitol Concentration and High Temperature by Microdroplet-Aided Adaptive Evolution. PMID:34540816
Mitochondrial DNA sequencing of a wet-collection syntype demonstrates the importance of type material as genetic resource for lantern shark taxonomy (Chondrichthyes: Etmopteridae). PMID:34540250
Identification of Potential Gene Regulatory Pathways Affecting the Ratio of Four-Seed Pod in Soybean. PMID:34539747
Multiple Wheat Genomes Reveal Novel Gli-2 Sublocus Location and Variation of Celiac Disease Epitopes in Duplicated α-Gliadin Genes. PMID:34539709
A Rickettsiella Endosymbiont Is a Potential Source of Essential B-Vitamins for the Poultry Red Mite, Dermanyssus gallinae. PMID:34539600
Effect of maternal separation and transportation stress on the bovine upper respiratory tract microbiome and the immune response to resident opportunistic pathogens. PMID:34538279
SARS-CoV-2 variant detection at a university dormitory using wastewater genomic tools. PMID:34536875
Phylogeographic reconstruction of the marbled crayfish origin. PMID:34535758
PIGG defines the Emm blood group system. PMID:34535746
Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa. PMID:34535742
Promoter-proximal elongation regulates transcription in archaea. PMID:34535658
Haplotype divergence supports long-term asexuality in the oribatid mite Oppiella nova. PMID:34535550
A survey of RNA editing at single-cell resolution links interneurons to schizophrenia and autism. PMID:34535545
Development and validation of a 1 K sika deer (Cervus nippon) SNP Chip. PMID:34535071
Proteogenomic characterization of pancreatic ductal adenocarcinoma. PMID:34534465
Hidden Historical Habitat-Linked Population Divergence and Contemporary Gene Flow of a Deep-Sea Patellogastropod Limpet. PMID:34534352
FACT-seq: profiling histone modifications in formalin-fixed paraffin-embedded samples with low cell numbers. PMID:34534335
The molecular architecture of Drosophila melanogaster defense against Beauveria bassiana explored through evolve and resequence and quantitative trait locus mapping. PMID:34534291
Chromosome-scale reference genome assembly of a diploid potato clone derived from an elite variety. PMID:34534288
Development and evaluation of a custom bait design based on 469 single-copy protein-coding genes for exon capture of isopods (Philosciidae: Haloniscus). PMID:34534224
Ancient genomics reveals tripartite origins of Japanese populations. PMID:34533991
DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability. PMID:34533226
Tissue macrophages and interferon-gamma signalling control blood-stage Plasmodium chabaudi infections derived from mosquito-transmitted parasites. PMID:34532703
A novel variant in fibrillin-1 is responsible for early-onset familial thoracic aortic aneurysms in Marfan patients. PMID:34532377
Phylogenetic analysis of HIV-1 shows frequent cross-country transmission and local population expansions. PMID:34532059
SLC5A3-Dependent Myo-inositol Auxotrophy in Acute Myeloid Leukemia. PMID:34531253
Comparative analysis reveals within-population genome size variation in a rotifer is driven by large genomic elements with highly abundant satellite DNA repeat elements. PMID:34530817
Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo. PMID:34529940
A population-level invasion by transposable elements triggers genome expansion in a fungal pathogen. PMID:34528512
Manipulation of TAD reorganization by chemical-dependent genome linking. PMID:34527956
Salmonella enterica from a soldier from the 1652 siege of Barcelona (Spain) supports historical transatlantic epidemic contacts. PMID:34527890
Identifying transcript 5' capped ends in Plasmodium falciparum. PMID:34527439
Pri smORF Peptides Are Wide Mediators of Ecdysone Signaling, Contributing to Shape Spatiotemporal Responses. PMID:34527021
A novel duplication involving PRDM13 in a Turkish family supports its role in North Carolina macular dystrophy (NCMD/MCDR1). PMID:34526759
Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks. PMID:34526718
UTX condensation underlies its tumour-suppressive activity. PMID:34526716
Evaluation of probiotic characteristics and whole genome analysis of Pediococcus pentosaceus MR001 for use as probiotic bacteria in shrimp aquaculture. PMID:34526534
Early-life midazolam exposure persistently changes chromatin accessibility to impair adult hippocampal neurogenesis and cognition. PMID:34526402
NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers. PMID:34524841
H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion. PMID:34524839
Assessment of two-pool multiplex long-amplicon nanopore sequencing of SARS-CoV-2. PMID:34524690
A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability. PMID:34524083
Exploring the Genomic Diversity and Antimicrobial Susceptibility of Bifidobacterium pseudocatenulatum in a Vietnamese Population. PMID:34523984
Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo. PMID:34522901
Replicate whole-genome next-generation sequencing data derived from Caucasian donor saliva samples. PMID:34522736
Deciphering complex genome rearrangements in C. elegans using short-read whole genome sequencing. PMID:34521941
The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites. PMID:34521898
Molecular underpinnings of division of labour among workers in a socially complex termite. PMID:34521896
Cystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered Myc expression. PMID:34521872
Genetic basis and adaptation trajectory of soybean from its temperate origin to tropics. PMID:34521854
Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma. PMID:34521827
Shortening of 3' UTRs in most cell types composing tumor tissues implicates alternative polyadenylation in protein metabolism. PMID:34521731
Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs. PMID:34521456
PRINCESS: comprehensive detection of haplotype resolved SNVs, SVs, and methylation. PMID:34521442
The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver. PMID:34520261
Rapid Macrosatellite Evolution Promotes X-Linked Hybrid Male Sterility in a Feline Interspecies Cross. PMID:34519828
The zinc-finger protein OEF-1 stabilizes histone modification patterns and promotes efficient splicing in the Caenorhabditis elegans germline. PMID:34519784
Rescuing Low Frequency Variants within Intra-Host Viral Populations directly from Oxford Nanopore sequencing data. PMID:34518837
Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine. PMID:34518628
CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression. PMID:34518536
INTS11 regulates hematopoiesis by promoting PRC2 function. PMID:34516911
Cell-free DNA TAPS provides multimodal information for early cancer detection. PMID:34516908
Interdependence of a mechanosensitive anion channel and glutamate receptors in distal wound signaling. PMID:34516872
Genome and transcriptome assemblies of the kuruma shrimp, Marsupenaeus japonicus. PMID:34515781
Mapping causal genes and genetic interactions for agronomic traits using a large F2 population in rice. PMID:34515770
Multiple introductions of multidrug-resistant typhoid associated with acute infection and asymptomatic carriage, Kenya. PMID:34515028
Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer. PMID:34514028
Integrative Epigenome Map of the Normal Human Prostate Provides Insights Into Prostate Cancer Predisposition. PMID:34513844
Co-Occurrence of Viruses, Plant Pathogens, and Symbionts in an Underexplored Hemipteran Clade. PMID:34513731
CABE-RY: A PAM-flexible dual-mutation base editor for reliable modeling of multi-nucleotide variants. PMID:34513298
AutoVEM2: A flexible automated tool to analyze candidate key mutations and epidemic trends for virus. PMID:34512928
Deep Sequencing of MHC-Adapted Viral Lines Reveals Complex Recombinational Exchanges With Endogenous Retroviruses Leading to High-Frequency Variants. PMID:34512727
Chromoanagenesis Event Underlies a de novo Pericentric and Multiple Paracentric Inversions in a Single Chromosome Causing Coffin-Siris Syndrome. PMID:34512724
Genetic and immune characteristics of multiple primary lung cancers and lung metastases. PMID:34510768
An integrated analysis of mRNAs, lncRNAs, and miRNAs based on weighted gene co-expression network analysis involved in bovine endometritis. PMID:34508138
Targeting chromosome trisomy for chromosome editing. PMID:34508128
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. PMID:34508101
Single-cell exome sequencing reveals multiple subclones in metastatic colorectal carcinoma. PMID:34507604
A near complete genome for goat genetic and genomic research. PMID:34507524
SORL1 mutation in a Greek family with Parkinson's disease and dementia. PMID:34506082
PEGS: An efficient tool for gene set enrichment within defined sets of genomic intervals. PMID:34504687
Fly-over phylogeny across invertebrate to vertebrate: The giant panda and insects share a highly similar gut microbiota. PMID:34504662
Genomic Prediction and the Practical Breeding of 12 Quantitative-Inherited Traits in Cucumber (Cucumis sativus L.). PMID:34504510
QTL Map of Early- and Late-Stage Perennial Regrowth in Zea diploperennis. PMID:34504508
Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling. PMID:34504285
A highly-contiguous genome assembly of the Eurasian spruce bark beetle, Ips typographus, provides insight into a major forest pest. PMID:34504275
Role of 53BP1 in end protection and DNA synthesis at DNA breaks. PMID:34503990
Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation. PMID:34503558
A genome-wide scan to identify signatures of selection in two Iranian indigenous chicken ecotypes. PMID:34503452
A POLE Splice Site Deletion Detected in a Patient with Biclonal CLL and Prostate Cancer: A Case Report. PMID:34502317
Genetic Architecture and Genome-Wide Adaptive Signatures Underlying Stem Lenticel Traits in Populus tomentosa. PMID:34502156
Overdominance at the Gene Expression Level Plays a Critical Role in the Hybrid Root Growth of Brassica napus. PMID:34502153
Hypervirulent Klebsiella pneumoniae Sequence Type 420 with a Chromosomally Inserted Virulence Plasmid. PMID:34502111
RNA Modifications in Genomic RNA of Influenza A Virus and the Relationship between RNA Modifications and Viral Infection. PMID:34502037
Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic. PMID:34499854
Opposing functions of the Hda1 complex and histone H2B mono-ubiquitylation in regulating cryptic transcription in Saccharomyces cerevisiae. PMID:34499735
Recipient APOL1 risk alleles associate with death-censored renal allograft survival and rejection episodes. PMID:34499625
Identification of sample mix-ups and mixtures in microbiome data in Diversity Outbred mice. PMID:34499168
Genome-Wide Association and Selective Sweep Studies Reveal the Complex Genetic Architecture of DMI Fungicide Resistance in Cercospora beticola. PMID:34499119
Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) orientalis, Isolate LSCM4, Strain LV768. PMID:34498920
Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) enriettii, Isolate CUR178, Strain LV763. PMID:34498918
Profiling nonhuman primate germline RNA to understand the legacy of early life stress. PMID:34498433
Genome Structural Variation Landscape and Its Selection Signatures in the Fast-growing Strains of the Pacific Oyster, Crassostrea gigas. PMID:34498173
Best practices for analyzing imputed genotypes from low-pass sequencing in dogs. PMID:34498136
Selection on Accessible Chromatin Regions in Capsella grandiflora. PMID:34498072
Infections by Transovarially Transmitted DMelSV in Drosophila Have No Impact on Ovarian Transposable Element Transcripts but Increase Their Amounts in the Soma. PMID:34498066
Intracellular Accumulation of IFN-λ4 Induces ER Stress and Results in Anti-Cirrhotic but Pro-HCV Effects. PMID:34497603
The EDS1-PAD4-ADR1 node mediates Arabidopsis pattern-triggered immunity. PMID:34497423
An integrated strategy for target SSR genotyping with toleration of nucleotide variations in the SSRs and flanking regions. PMID:34496768
Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients. PMID:34496298
Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. PMID:34496258
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity. PMID:34496233
A supernumerary "B-sex" chromosome drives male sex determination in the Pachón cavefish, Astyanax mexicanus. PMID:34496222
Glioblastoma signature in the DNA of blood-derived cells. PMID:34495981
VC@Scale: Scalable and high-performance variant calling on cluster environments. PMID:34494101
Variant abundance estimation for SARS-CoV-2 in wastewater using RNA-Seq quantification. PMID:34494031
Genomic insights into the origin, domestication and diversification of Brassica juncea. PMID:34493868
A compendium of uniformly processed human gene expression and splicing quantitative trait loci. PMID:34493866
Molecular profiling of advanced solid tumours. The impact of experimental molecular-matched therapies on cancer patient outcomes in early-phase trials: the MAST study. PMID:34493820
Nanopore sequencing and de novo assembly of a misidentified Camelpox vaccine reveals putative epigenetic modifications and alternate protein signal peptides. PMID:34493784
The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma. PMID:34493320
A tetraploidization event shaped the Aquilaria sinensis genome and contributed to the ability of sesquiterpenes synthesis. PMID:34493201
Therapy-related myeloid neoplasms in 109 patients after radiation monotherapy. PMID:34492705
CSYseq: The first Y-chromosome sequencing tool typing a large number of Y-SNPs and Y-STRs to unravel worldwide human population genetics. PMID:34491993
DNase Treatment Improves Viral Enrichment in Agricultural Soil Viromes. PMID:34491084
Human Adenovirus Type 7 Infections in Hubei, China During 2018-2019: Epidemic Features and Genetic Characterization of the Detected Viruses. PMID:34490137
Genomic-Assisted Marker Development Suitable for CsCvy-1 Selection in Cucumber Breeding. PMID:34489994
Analysis of Bulk RNA Sequencing Data Reveals Novel Transcription Factors Associated With Immune Infiltration Among Multiple Cancers. PMID:34489925
Genomic Variation Influences Methanothermococcus Fitness in Marine Hydrothermal Systems. PMID:34489903
Pseudomonas palmensis sp. nov., a Novel Bacterium Isolated From Nicotiana glauca Microbiome: Draft Genome Analysis and Biological Potential for Agriculture. PMID:34489881
Case Report: Consecutive Adrenal Cushing's Syndrome and Cushing's Disease in a Patient With Somatic CTNNB1, USP8, and NR3C1 Mutations. PMID:34489873
Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs. PMID:34489573
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer. PMID:34489572
Whole genome sequences reveal the Xanthomonas perforans population is shaped by the tomato production system. PMID:34489540
Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells. PMID:34489473
Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance. PMID:34489413
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution. PMID:34489412
Profiling diverse sequence tandem repeats in colorectal cancer reveals co-occurrence of microsatellite and chromosomal instability involving Chromosome 8. PMID:34488871
Gramtools enables multiscale variation analysis with genome graphs. PMID:34488837
NanoCaller for accurate detection of SNPs and indels in difficult-to-map regions from long-read sequencing by haplotype-aware deep neural networks. PMID:34488830
Mitonuclear mismatch alters nuclear gene expression in naturally introgressed Rhinolophus bats. PMID:34488775
Profiling of chromatin accessibility identifies transcription factor binding sites across the genome of Aspergillus species. PMID:34488759
Positive selection of skeleton-related genes during duck domestication revealed by whole genome sequencing. PMID:34488647
Single-minded 2 is required for left-right asymmetric stomach morphogenesis. PMID:34486651
Increased rates of secondary bacterial infections, including Enterococcus bacteremia, in patients hospitalized with coronavirus disease 2019 (COVID-19). PMID:34486503
Construction of transcriptional regulatory networks using total RNA-seq data. PMID:34485938
Low-input ATAC&mRNA-seq protocol for simultaneous profiling of chromatin accessibility and gene expression. PMID:34485936
fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins. PMID:34485935
Whole genome sequencing data of Klebsiella aerogenes isolated from agricultural soil of Haryana, India. PMID:34485641
Pacbio Sequencing of PLC/PRF/5 Cell Line and Clearance of HBV Integration Through CRISPR/Cas-9 System. PMID:34485380
Museum Genomics Illuminate the High Specificity of a Bioluminescent Symbiosis for a Genus of Reef Fish. PMID:34485316
Psi-Caller: A Lightweight Short Read-Based Variant Caller With High Speed and Accuracy. PMID:34485311
RetroScan: An Easy-to-Use Pipeline for Retrocopy Annotation and Visualization. PMID:34484306
Genetic Diversity of MHC B-F/B-L Region in 21 Chicken Populations. PMID:34484301
CNV-MEANN: A Neural Network and Mind Evolutionary Algorithm-Based Detection of Copy Number Variations From Next-Generation Sequencing Data. PMID:34484298
Genomic Variation Landscape of the Model Salt Cress Eutrema salsugineum. PMID:34484264
Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution. PMID:34480159
Challenges for the standardized reporting of NGS HLA genotyping: Surveying gaps between clinical and research laboratories. PMID:34479742
Arms race in a cell: genomic, transcriptomic, and proteomic insights into intracellular phage-bacteria interplay in deep-sea snail holobionts. PMID:34479645
Elucidating the mechanism by which synthetic helper peptides sensitize Pseudomonas aeruginosa to multiple antibiotics. PMID:34478485
LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells. PMID:34477552
Whole-genome-based phylogenomic analysis of the Belgian 2016-2017 influenza A(H3N2) outbreak season allows improved surveillance. PMID:34477544
Clonal dynamics of circulating tumor DNA during immune checkpoint blockade therapy for melanoma. PMID:34477284
Molecular genetic evaluation of pediatric renovascular hypertension due to renal artery stenosis and abdominal aortic coarctation in neurofibromatosis type 1. PMID:34476477
Programmed genome editing by a miniature CRISPR-Cas12f nuclease. PMID:34475565
Indicators of the molecular pathogenesis of virulent Newcastle disease virus in chickens revealed by transcriptomic profiling of spleen. PMID:34475461
Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk. PMID:34475392
Cell reprogramming shapes the mitochondrial DNA landscape. PMID:34475388
Biochemically deleterious human NFKB1 variants underlie an autosomal dominant form of common variable immunodeficiency. PMID:34473196
High-resolution microbiome analysis enabled by linking of 16S rRNA gene sequences with adjacent genomic contexts. PMID:34473015
Complete Genome Sequence of Rhodococcus sp. Strain W8901, a Human Clinical Specimen, Assembled Using MiSeq and MinION Sequence Data. PMID:34472975
miRNome profiling in Duchenne muscular dystrophy; identification of asymptomatic and manifesting female carriers. PMID:34472584
Evolutionary history of two rare endemic conifer species from the eastern Qinghai-Tibet Plateau. PMID:34472580
Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer. PMID:34471425
Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis. PMID:34471131
Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development. PMID:34471115
Layilin Anchors Regulatory T Cells in Skin. PMID:34470859
Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome. PMID:34469736
Drosophila Evolution over Space and Time (DEST): A New Population Genomics Resource. PMID:34469576
Evidence in disease and non-disease contexts that nonsense mutations cause altered splicing via motif disruption. PMID:34469537
Viral Characteristics of the Warm Atlantic and Cold Arctic Water Masses in the Nordic Seas. PMID:34469192
Transcriptomic Responses to Coaggregation between Streptococcus gordonii and Streptococcus oralis. PMID:34469191
Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights. PMID:34468193
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology. PMID:34467244
Molecular analysis of the 2012 Bundibugyo virus disease outbreak. PMID:34467242
Immunomodulation-A Molecular Solution to Treating Patients with Severe Bladder Pain Syndrome? PMID:34467240
Chromatin and transcription factor profiling in rare stem cell populations using CUT&Tag. PMID:34467227
ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer. PMID:34466783
Genetic diversity and population structure of a global invader Mayweed chamomile (Anthemis cotula): management implications. PMID:34466213
Genome-driven elucidation of phage-host interplay and impact of phage resistance evolution on bacterial fitness. PMID:34465897
Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma. PMID:34465776
Assessing the origins of the European Plagues following the Black Death: A synthesis of genomic, historical, and ecological information. PMID:34465619
Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins. PMID:34465585
Functional microRNA targetome undergoes degeneration-induced shift in the retina. PMID:34465369
AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data. PMID:34465366
Aspergillus fumigatus In-Host HOG Pathway Mutation for Cystic Fibrosis Lung Microenvironment Persistence. PMID:34465017
R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements. PMID:34464389
Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii. PMID:34464380
Targeting enhancer reprogramming to mitigate MEK inhibitor resistance in preclinical models of advanced ovarian cancer. PMID:34464356
Intragenic tRNA-promoted R-loops orchestrate transcription interference for plant oxidative stress responses. PMID:34463741
Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation. PMID:34463256
The bowfin genome illuminates the developmental evolution of ray-finned fishes. PMID:34462605
Genomic data and multi-species demographic modelling uncover past hybridization between currently allopatric freshwater species. PMID:34462578
Building a Chinese pan-genome of 486 individuals. PMID:34462542
Whole genome sequencing of clinical samples reveals extensively drug resistant tuberculosis (XDR TB) strains from the Beijing lineage in Nigeria, West Africa. PMID:34462504
Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis. PMID:34462327
GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning. PMID:34461978
The genetics and evolution of eye color in domestic pigeons (Columba livia). PMID:34460822
The Easter Egg Weevil (Pachyrhynchus) genome reveals syntenic patterns in Coleoptera across 200 million years of evolution. PMID:34460814
Role of Epistasis in Amikacin, Kanamycin, Bedaquiline, and Clofazimine Resistance in Mycobacterium tuberculosis Complex. PMID:34460306
Increasing frequency of OXA-48-producing Enterobacterales worldwide and activity of ceftazidime/avibactam, meropenem/vaborbactam and comparators against these isolates. PMID:34459890
The prognostic landscape of genes and infiltrating immune cells in cytokine induced killer cell treated-lung squamous cell carcinoma and adenocarcinoma. PMID:34459571
Metabolic potential of the imperfect denitrifier Candidatus Desulfobacillus denitrificans in an anammox bioreactor. PMID:34459550
A modified CUT&RUN protocol and analysis pipeline to identify transcription factor binding sites in human cell lines. PMID:34458869
Semicoordinated allelic-bursting shape dynamic random monoallelic expression in pregastrulation embryos. PMID:34458702
Comparative proteomic investigation of multiple methicillin-resistant Staphylococcus aureus strains generated through adaptive laboratory evolution. PMID:34458699
Trigenic ADH5/ALDH2/ADGRV1 mutations in myelodysplasia with Usher syndrome. PMID:34458631
Discovery of Novel Host Molecular Factors Underlying HBV/HCV Infection. PMID:34458256
Reference-based assembly of chloroplast genome from leaf transcriptome data of Pterocarpus santalinus. PMID:34458062
A Missense Mutation in the MYBPH Gene Is Associated With Abdominal Fat Traits in Meat-Type Chickens. PMID:34456973
Identification of BRCA2 Cis Double Heterozygous Breast Cancer Cases Using Whole Exome Sequencing: Phenotypic Expression and Impact on Personalized Oncology. PMID:34456966
Far-Red Light-Induced Azolla filiculoides Symbiosis Sexual Reproduction: Responsive Transcripts of Symbiont Nostoc azollae Encode Transporters Whilst Those of the Fern Relate to the Angiosperm Floral Transition. PMID:34456937
Longitudinal study on the effects of growth-promoting and therapeutic antibiotics on the dynamics of chicken cloacal and litter microbiomes and resistomes. PMID:34454634
Evaluation of low-pass genome sequencing in polygenic risk score calculation for Parkinson's disease. PMID:34454617
The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions. PMID:34454597
The first genome assembly of fungal pathogen Pyrenophora tritici-repentis race 1 isolate using Oxford Nanopore MinION sequencing. PMID:34454585
Comparative genomic analysis of a naturally born serpentized pig reveals putative mutations related to limb and bone development. PMID:34454433
Homoeologous chromosome exchange explains the creation of a QTL affecting soil-borne pathogen resistance in tobacco. PMID:34453871
Linking circular intronic RNA degradation and function in transcription by RNase H1. PMID:34453665
Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting. PMID:34453119
CTCF and transcription influence chromatin structure re-configuration after mitosis. PMID:34453048
The PEMDAC phase 2 study of pembrolizumab and entinostat in patients with metastatic uveal melanoma. PMID:34453044
Pathway conversion enables a double-lock mechanism to maintain DNA methylation and genome stability. PMID:34453006
Multi-Tissue Transcriptomic-Informed In Silico Investigation of Drugs for the Treatment of Dengue Fever Disease. PMID:34452405
Species Delimitation and Conservation in Taxonomically Challenging Lineages: The Case of Two Clades of Capurodendron (Sapotaceae) in Madagascar. PMID:34451747
Patterns of Genetic Variation in a Soybean Germplasm Collection as Characterized with Genotyping-by-Sequencing. PMID:34451656
Predominance of the SARS-CoV-2 Lineage P.1 and Its Sublineage P.1.2 in Patients from the Metropolitan Region of Porto Alegre, Southern Brazil in March 2021. PMID:34451453
Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression. PMID:34450030
Inhibition of the lncRNA Coded within Transglutaminase 2 Gene Impacts Several Relevant Networks in MCF-7 Breast Cancer Cells. PMID:34449674
Shining light on a deep-sea bacterial symbiont population structure with CRISPR. PMID:34448690
A Comprehensive Guide to Potato Transcriptome Assembly. PMID:34448160
Topically delivered 22 nt siRNAs enhance RNAi silencing of endogenous genes in two species. PMID:34448043
The complete chloroplast genome of Castanopsis sieboldii (Makino) Hatus (Fagaceae). PMID:34447890
Analysis of the Segregation Distortion of FcRAN1 Genotypes Based on Whole-Genome Resequencing of Fig (Ficus carica L.) Breeding Parents. PMID:34447395
Pan-transcriptome identifying master genes and regulation network in response to drought and salt stresses in Alfalfa (Medicago sativa L.). PMID:34446782
A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm. PMID:34446717
ENHANCED GRAVITROPISM 2 encodes a STERILE ALPHA MOTIF-containing protein that controls root growth angle in barley and wheat. PMID:34446550
Glucocorticoid signaling induces transcriptional memory and universally reversible chromatin changes. PMID:34446533
Human reference gut microbiome catalog including newly assembled genomes from under-represented Asian metagenomes. PMID:34446072
Global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain. PMID:34446036
Allele frequency deviation (AFD) as a new prognostic model to predict overall survival in lung adenocarcinoma (LUAD). PMID:34446004
Cappable-Seq Reveals Specific Patterns of Metabolism and Virulence for Salmonella Typhimurium Intracellular Survival within Acanthamoeba castellanii. PMID:34445780
Uncovering Microbial Composition in Human Breast Cancer Primary Tumour Tissue Using Transcriptomic RNA-seq. PMID:34445764
LINC01133 Inhibits Invasion and Promotes Proliferation in an Endometriosis Epithelial Cell Line. PMID:34445100
Features of the Opportunistic Behaviour of the Marine Bacterium Marinobacter algicola in the Microalga Ostreococcus tauri Phycosphere. PMID:34442856
The Sisal Virome: Uncovering the Viral Diversity of Agave Varieties Reveals New and Organ-Specific Viruses. PMID:34442783
Whole Genome Sequencing Refines Knowledge on the Population Structure of Mycobacterium bovis from a Multi-Host Tuberculosis System. PMID:34442664
Experimental Selection of Paromomycin Resistance in Leishmania donovani Amastigotes Induces Variable Genomic Polymorphisms. PMID:34442625
Enhanced Expression of Thaumatin-like Protein Gene (LeTLP1) Endows Resistance to Trichoderma atroviride in Lentinula edodes. PMID:34440607
Comparative Analysis of PacBio and Oxford Nanopore Sequencing Technologies for Transcriptomic Landscape Identification of Penaeus monodon. PMID:34440606
A Novel Missense Mutation in TNNI3K Causes Recessively Inherited Cardiac Conduction Disease in a Consanguineous Pakistani Family. PMID:34440456
Population Genomics Reveals Gene Flow and Adaptive Signature in Invasive Weed Mikania micrantha. PMID:34440453
Whole Genome Sequencing Reveals Multiple Linked Genetic Variants on Canine Chromosome 12 Associated with Risk for Symmetrical Lupoid Onychodystrophy (SLO) in the Bearded Collie. PMID:34440439
Utility of Gene Panels for the Diagnosis of Inborn Errors of Metabolism in a Metabolic Reference Center. PMID:34440436
Diversity and Paleodemography of the Addax (Addax nasomaculatus), a Saharan Antelope on the Verge of Extinction. PMID:34440410
QTL Genetic Mapping Study for Traits Affecting Meal Quality in Winter Oilseed Rape (Brassica Napus L.). PMID:34440409
Mitogenome Phylogeny Including Data from Additional Subspecies Provides New Insights into the Historical Biogeography of the Eurasian lynx Lynx lynx. PMID:34440390
Identification of Copy Number Variants in a Southern Chinese Cohort of Patients with Congenital Scoliosis. PMID:34440387
Identification and Validation of Marketing Weight-Related SNP Markers Using SLAF Sequencing in Male Yangzhou Geese. PMID:34440377
Methylation of Host Genes Associated with Coronavirus Infection from Birth to 26 Years. PMID:34440372
Genomic Characterization of Fluoroquinolone-Resistant Thermophilic Campylobacter Strains Isolated from Layer Chicken Feces in Gangneung, South Korea by Whole-Genome Sequencing. PMID:34440305
Contrasting Host-Parasite Population Structure: Morphology and Mitogenomics of a Parasitic Flatworm on Pelagic Deepwater Cichlid Fishes from Lake Tanganyika. PMID:34440029
New Approach for Detection of Normal Alternative Splicing Events and Aberrant Spliceogenic Transcripts with Long-Range PCR and Deep RNA Sequencing. PMID:34439939
Analytical Performance of NGS-Based Molecular Genetic Tests Used in the Diagnostic Workflow of Pheochromocytoma/Paraganglioma. PMID:34439371
In Search of Species-Specific SNPs in a Non-Model Animal (European Bison (Bison bonasus))-Comparison of De Novo and Reference-Based Integrated Pipeline of STACKS Using Genotyping-by-Sequencing (GBS) Data. PMID:34438684
Maxicircle architecture and evolutionary insights into Trypanosoma cruzi complex. PMID:34437557
Exploring STR sequencing for forensic DNA intelligence databasing using the Austrian National DNA Database as an example. PMID:34436655
Evolutionary Profile for (Host and Viral) MLKL Indicates Its Activities as a Battlefront for Extensive Counteradaptation. PMID:34436583
Virulence Traits and Population Genomics of the Black Yeast Aureobasidium melanogenum. PMID:34436204
Method of targeted bisulfite massive parallel sequencing of the human LINE-1 retrotransposon promoter. PMID:34434857
A body map of somatic mutagenesis in morphologically normal human tissues. PMID:34433965
Dynamic changes in genomic and social structures in third millennium BCE central Europe. PMID:34433570
Sex or cannibalism: Polyphenism and kin recognition control social action strategies in nematodes. PMID:34433565
Fast and SNP-aware short read alignment with SALT. PMID:34433415
Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis. PMID:34432858
Chromoanagenesis from radiation-induced genome damage in Populus. PMID:34432802
Intraspecific Transcriptome Variation and Sex-Biased Expression in Anopheles arabiensis. PMID:34432020
Crosstalk between nitric oxide and retinoic acid pathways is essential for amphioxus pharynx development. PMID:34431784
Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment. PMID:34431691
Transcriptomic response of Daphnia magna to nitrogen- or phosphorus-limited diet. PMID:34429898
Overcoming the growth-infectivity trade-off in a bacteriophage slows bacterial resistance evolution. PMID:34429748
Genetic engineering of marine cyanophages reveals integration but not lysogeny in T7-like cyanophages. PMID:34429521
Acute depletion of CTCF rewires genome-wide chromatin accessibility. PMID:34429148
TERA-Seq: true end-to-end sequencing of native RNA molecules for transcriptome characterization. PMID:34428294
Acquisition and loss of CTX-M plasmids in Shigella species associated with MSM transmission in the UK. PMID:34427554
Microbiota Perturbation or Elimination Can Inhibit Normal Development and Elicit a Starvation-Like Response in an Omnivorous Model Invertebrate. PMID:34427529
Horizontal Gene Transfer Is the Main Driver of Antimicrobial Resistance in Broiler Chicks Infected with Salmonella enterica Serovar Heidelberg. PMID:34427525
Machine Learning Prediction of Resistance to Subinhibitory Antimicrobial Concentrations from Escherichia coli Genomes. PMID:34427505
Ecological Specialization and Evolutionary Reticulation in Extant Hyaenidae. PMID:34426844
Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases. PMID:34426706
INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants. PMID:34425882
Systematic functional interrogation of human pseudogenes using CRISPRi. PMID:34425866
Uncovering the genomic and metagenomic research potential in old ethanol-preserved snakes. PMID:34424926
Exploring the evolutionary process of alkannin/shikonin O-acyltransferases by a reliable Lithospermum erythrorhizon genome. PMID:34424327
Population genomics of transposable element activation in the highly repressive genome of an agricultural pathogen. PMID:34424154
Identification and Characterization of Pleiotropic High-Persistence Mutations in the Beta Subunit of the Bacterial RNA Polymerase. PMID:34424038
Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression. PMID:34423893
Severe Acute Respiratory Syndrome Coronavirus 2 in Farmed Mink (Neovison vison), Poland. PMID:34423763
Androgen Activity Is Associated With PD-L1 Downregulation in Thyroid Cancer. PMID:34422798
Genetic composition and evolution of the prevalent Mycobacterium tuberculosis lineages 2 and 4 in the Chinese and Zhejiang Province populations. PMID:34419157
Identification of key genes affecting porcine fat deposition based on co-expression network analysis of weighted genes. PMID:34419151
Prevotella copri increases fat accumulation in pigs fed with formula diets. PMID:34419147
Bidirectional epithelial-mesenchymal crosstalk provides self-sustaining profibrotic signals in pulmonary fibrosis. PMID:34418430
Dynamic landscape of chromatin accessibility and transcriptomic changes during differentiation of human embryonic stem cells into dopaminergic neurons. PMID:34417498
Haplotype-resolved de novo assembly of the Vero cell line genome. PMID:34417462
Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4. PMID:34417458
Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes. PMID:34417450
Technological advances in cancer immunity: from immunogenomics to single-cell analysis and artificial intelligence. PMID:34417437
Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity. PMID:34417184
Neuronal control of maternal provisioning in response to social cues. PMID:34417172
Megabase-scale presence-absence variation with Tripsacum origin was under selection during maize domestication and adaptation. PMID:34416918
NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior. PMID:34416169
Finding differentially expressed sRNA-Seq regions with srnadiff. PMID:34415926
SNPs in Mammary Gland Epithelial Cells Unraveling Potential Difference in Milk Production Between Jersey and Kashmiri Cattle Using RNA Sequencing. PMID:34413874
Gradual evolution of allopolyploidy in Arabidopsis suecica. PMID:34413506
An example of DNA methylation as a means to quantify stress in wildlife using killer whales. PMID:34413356
A genome epidemiological study of mycobacterium tuberculosis in subpopulations with high and low incidence rate in Guangxi, South China. PMID:34412585
Patterns of genetic connectedness between modern and medieval Estonian genomes reveal the origins of a major ancestry component of the Finnish population. PMID:34411538
Whole-Genome Sequencing of a 900-Year-Old Human Skeleton Supports Two Past Migration Events from the Russian Far East to Northern Japan. PMID:34410389
Demographic History of the Brown Bear (Ursus arctos) on Hokkaido Island, Japan, Based on Whole-Genomic Sequence Analysis. PMID:34410373
Genome Sequence of Lymphocystis Disease Virus 2 LCDV-JP_Oita_2018, Isolated from a Diseased Japanese Flounder (Paralichthys olivaceus) in Japan. PMID:34410157
Nhp2 is a reader of H2AQ105me and part of a network integrating metabolism with rRNA synthesis. PMID:34409714
Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1. PMID:34409300
The discovery, distribution, and diversity of DNA viruses associated with Drosophila melanogaster in Europe. PMID:34408913
Genome-Wide Association Study Using Whole-Genome Sequencing Identifies a Genomic Region on Chromosome 6 Associated With Comb Traits in Nandan-Yao Chicken. PMID:34408769
TP53 Mutation Related and Directly Regulated lncRNA Prognosis Markers in Hepatocellular Carcinoma. PMID:34408439
Reconstructing genetic histories and social organisation in Neolithic and Bronze Age Croatia. PMID:34408163
Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast. PMID:34408137
Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel. PMID:34408017
The histone chaperone Anp32e regulates memory formation, transcription, and dendritic morphology by regulating steady-state H2A.Z binding in neurons. PMID:34407406
Plastome variation and phylogeny of Taxillus (Loranthaceae). PMID:34407123
De novo centromere formation on chromosome fragments with an inactive centromere in maize (Zea mays). PMID:34406545
Delaying or delivering: identification of novel NAM-1 alleles that delay senescence to extend wheat grain fill duration. PMID:34405865
Time-dependent effect of 1,6-hexanediol on biomolecular condensates and 3D chromatin organization. PMID:34404453
Natural infection of Delta mutant of SARS-CoV-2 in Asiatic lions of India. PMID:34404118
The Rsm (Csr) post-transcriptional regulatory pathway coordinately controls multiple CRISPR-Cas immune systems. PMID:34403463
Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancy. PMID:34401410
Rapid high-resolution melting genotyping scheme for Escherichia coli based on MLST derived single nucleotide polymorphisms. PMID:34400722
Genome-wide comparative analyses of GATA transcription factors among seven Populus genomes. PMID:34400697
Novel somatic variants involved in biochemical activity of pure growth hormone-secreting pituitary adenoma without GNAS variant. PMID:34400688
Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies. PMID:34400676
Global range expansion history of pepper (Capsicum spp.) revealed by over 10,000 genebank accessions. PMID:34400501
Chromatin interaction neural network (ChINN): a machine learning-based method for predicting chromatin interactions from DNA sequences. PMID:34399797
A novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancer. PMID:34399705
Large-scale transcriptome sequencing in broiler chickens to identify candidate genes for breast muscle weight and intramuscular fat content. PMID:34399688
Genome-wide association study of individual sugar content in fruit of Japanese pear (Pyrus spp.). PMID:34399685
A New Model Trypanosomatid, Novymonas esmeraldas: Genomic Perception of Its "Candidatus Pandoraea novymonadis" Endosymbiont. PMID:34399629
Hidden Viral Sequences in Public Sequencing Data and Warning for Future Emerging Diseases. PMID:34399612
Monomorphic Trypanozoon: towards reconciling phylogeny and pathologies. PMID:34397347
Tethered Chromosome Conformation Capture Sequencing in Triticeae: A Valuable Tool for Genome Assembly. PMID:34395764
Lung Transplant Improves Survival and Quality of Life Regardless of Telomere Dysfunction. PMID:34395476
Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells. PMID:34395436
Genomics pipelines to investigate susceptibility in whole genome and exome sequenced data for variant discovery, annotation, prediction and genotyping. PMID:34395068
Genome-Wide Association Study of Root and Shoot Related Traits in Spring Soybean (Glycine max L.) at Seedling Stages Using SLAF-Seq. PMID:34394134
Motor Stereotypic Behavior Was Associated With Immune Response in Macaques: Insight From Transcriptome and Gut Microbiota Analysis. PMID:34394017
Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe-4S cluster and regulates Fe-S cluster biogenesis for persistence in mice. PMID:34392160
Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma. PMID:34391887
HELLO: improved neural network architectures and methodologies for small variant calling. PMID:34391391
Segmental duplication as potential biomarkers for non-invasive prenatal testing of aneuploidies. PMID:34391089
Target capture sequencing of SARS-CoV-2 genomes using the ONETest Coronaviruses Plus. PMID:34391075
A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Leprdb/db mice. PMID:34390703
A mutation in LacDWARF1 results in a GA-deficient dwarf phenotype in sponge gourd (Luffa acutangula). PMID:34390352
Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells. PMID:34390351
Metapangenomics reveals depth-dependent shifts in metabolic potential for the ubiquitous marine bacterial SAR324 lineage. PMID:34389059
Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells. PMID:34389041
A single amino acid residue substitution in BraA04g017190.3C, a histone methyltransferase, results in premature bolting in Chinese cabbage (Brassica rapa L. ssp. Pekinensis). PMID:34388969
Developmental and temporal characteristics of clonal sperm mosaicism. PMID:34388390
Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging. PMID:34388375
The DNA-to-cytoplasm ratio broadly activates zygotic gene expression in Xenopus. PMID:34388374
MicroRNA-1205 Regulation of FRYL in Prostate Cancer. PMID:34386489
Antimicrobial Resistance Profiling and Phylogenetic Analysis of Neisseria gonorrhoeae Clinical Isolates From Kenya in a Resource-Limited Setting. PMID:34385981
Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations. PMID:34385540
Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors. PMID:34385467
Genome accessibility dynamics in response to phosphate limitation is controlled by the PHR1 family of transcription factors in Arabidopsis. PMID:34385324
Connection of core and tail Mediator modules restrains transcription from TFIID-dependent promoters. PMID:34383744
Simultaneous Tagmentation-Based Detection of ChIP/ATAC Signal with Bisulfite Sequencing. PMID:34382199
Genome-Wide Profiling of Protein-DNA Interactions with Chromatin Endogenous Cleavage and High-Throughput Sequencing (ChEC-Seq ). PMID:34382196
Salmonella Typhimurium ST313 isolated in Brazil revealed to be more invasive and inflammatory in murine colon compared to ST19 strains. PMID:34382146
Data on the first functionally-annotated de novo transcriptome assembly for North American flying squirrels (genus Glaucomys). PMID:34381854
A novel cryptic splice site mutation in COL1A2 as a cause of osteogenesis imperfecta. PMID:34381850
Sequence of the Mitochondrial Genome of Lactuca virosa Suggests an Unexpected Role in Lactuca sativa's Evolution. PMID:34381482
Effect of black ginseng and silkworm supplementation on obesity, the transcriptome, and the gut microbiome of diet-induced overweight dogs. PMID:34381138
Bog ecosystems as a playground for plant-microbe coevolution: bryophytes and vascular plants harbour functionally adapted bacteria. PMID:34380552
Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis. PMID:34380064
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing. PMID:34380018
A novel mechanism of enhanced transcription activity and fidelity for influenza A viral RNA-dependent RNA polymerase. PMID:34379778
A wAlbB Wolbachia Transinfection Displays Stable Phenotypic Effects across Divergent Aedes aegypti Mosquito Backgrounds. PMID:34379518
Enterovirus A71 Induces Neurological Diseases and Dynamic Variants in Oral Infection of Human SCARB2-Transgenic Weaned Mice. PMID:34379497
Population Informative Markers Selected Using Wright's Fixation Index and Machine Learning Improves Human Identification Using the Skin Microbiome. PMID:34379455
SARS-CoV-2 Isolates Show Impaired Replication in Human Immune Cells but Differential Ability to Replicate and Induce Innate Immunity in Lung Epithelial Cells. PMID:34378952
The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs. PMID:34377966
The complete mitochondrial genome of Periacma orthiodes Meyrick, 1894 (Lepidoptera: Autostichidae). PMID:34377834
Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae). PMID:34377832
The complete mitochondrial genome of Meleonoma mirabilis (Wang 2003) (Lepidoptera: Autostichidae). PMID:34377790
Genome-wide mapping of binding sites of the transposase-derived SETMAR protein in the human genome. PMID:34377368
Development of PCR-based DNA marker for detection of white carrot contamination caused by Y2 locus. PMID:34377068
The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster. PMID:34376687
Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. PMID:34376672
Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans. PMID:34376665
Genome-level diversification of eight ancient tea populations in the Guizhou and Yunnan regions identifies candidate genes for core agronomic traits. PMID:34376642
Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique. PMID:34376564
INGOT-DR: an interpretable classifier for predicting drug resistance in M. tuberculosis. PMID:34376217
Outbreak or pseudo-outbreak? Integrating SARS-CoV-2 sequencing to validate infection control practices in a dialysis facility. PMID:34375700
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation. PMID:34375583
Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver. PMID:34375333
Dominance of Alpha and Iota variants in SARS-CoV-2 vaccine breakthrough infections in New York City. PMID:34375308
Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis. PMID:34375307
Nonsense variant of NR0B1 causes hormone disorders associated with congenital adrenal hyperplasia. PMID:34373561
Genomic Diversity of Azole-Resistant Aspergillus fumigatus in the United States. PMID:34372699
Multifactorial Role of Mitochondria in Echinocandin Tolerance Revealed by Transcriptome Analysis of Drug-Tolerant Cells. PMID:34372698
Fine Mapping of the Gene Controlling the Fruit Skin Hairiness of Prunus persica and Its Uses for MAS in Progenies. PMID:34371636
Genome Wide MeDIP-Seq Profiling of Wild and Cultivated Olives Trees Suggests DNA Methylation Fingerprint on the Sensory Quality of Olive Oil. PMID:34371608
ZWA: Viral genome assembly and characterization hindrances from virus-host chimeric reads; a refining approach. PMID:34370725
Discovering differential genome sequence activity with interpretable and efficient deep learning. PMID:34370721
Post-weaning shifts in microbiome composition and metabolism revealed by over 25 000 pig gut metagenome-assembled genomes. PMID:34370660
JWES: a new pipeline for whole genome/exome sequence data processing, management, and gene-variant discovery, annotation, prediction, and genotyping. PMID:34370400
Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid. PMID:34369989
Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters. PMID:34369651
Structural Variations of the 3D Genome Architecture in Cervical Cancer Development. PMID:34368157
The Landscape of Genetic Alterations Stratified Prognosis in Oriental Pancreatic Cancer Patients. PMID:34368001
Adaptive and maladaptive expression plasticity underlying herbicide resistance in an agricultural weed. PMID:34367667
Low-coverage whole-genome sequencing reveals molecular markers for spawning season and sex identification in Gulf of Maine Atlantic cod (Gadus morhua, Linnaeus 1758). PMID:34367604
Conservation implications of genetic structure in the narrowest endemic quillwort from the Eastern Amazon. PMID:34367563
RESIC: A Tool for Comprehensive Adenosine to Inosine RNA Editing Site Identification and Classification. PMID:34367244
Ultra-High-Density QTL Marker Mapping for Seedling Photomorphogenesis Mediating Arabidopsis Establishment in Southern Patagonia. PMID:34367202
Accurate Detection and Quantification of FLT3 Internal Tandem Duplications in Clinical Hybrid Capture Next-Generation Sequencing Data. PMID:34363960
Overdominant Mutations Restrict Adaptive Loss of Heterozygosity at Linked Loci. PMID:34363476
The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors. PMID:34362909
Purple sulfur bacteria fix N2 via molybdenum-nitrogenase in a low molybdenum Proterozoic ocean analogue. PMID:34362886
Olfactory receptor-dependent receptor repression in Drosophila. PMID:34362730
Large scale genomic rearrangements in selected Arabidopsis thaliana T-DNA lines are caused by T-DNA insertion mutagenesis. PMID:34362298
Exploiting genomic synteny in Felidae: cross-species genome alignments and SNV discovery can aid conservation management. PMID:34362297
Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair events. PMID:34362292
Dual RNA-Seq Enables Full-Genome Assembly of Measles Virus and Characterization of Host-Pathogen Interactions. PMID:34361973
HERON: A Novel Tool Enables Identification of Long, Weakly Enriched Genomic Domains in ChIP-seq Data. PMID:34360892
SARS-CoV-2 Infected Pediatric Cerebral Cortical Neurons: Transcriptomic Analysis and Potential Role of Toll-like Receptors in Pathogenesis. PMID:34360824
FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes. PMID:34359927
Ancestral Sperm Ecotypes Reveal Multiple Invasions of a Non-Native Fish in Northern Europe. PMID:34359913
Chromosomal Translocations in NK-Cell Lymphomas Originate from Inter-Chromosomal Contacts of Active rDNA Clusters Possessing Hot Spots of DSBs. PMID:34359791
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. PMID:34358448
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency. PMID:34358447
Cell-type-specific Hox regulatory strategies orchestrate tissue identity. PMID:34358443
Whole-Genome Sequencing Analysis to Identify Infection with Multiple Species of Nontuberculous Mycobacteria. PMID:34358029
Proteo-Trancriptomic Analyses Reveal a Large Expansion of Metalloprotease-Like Proteins in Atypical Venom Vesicles of the Wasp Meteorus pulchricornis (Braconidae). PMID:34357975
Integration of Complete Plasmids Containing Bont Genes into Chromosomes of Clostridium parabotulinum, Clostridium sporogenes, and Clostridium argentinense. PMID:34357945
mRNA Inventory of Extracellular Vesicles from Ustilago maydis. PMID:34356940
Male Differentiation in the Marine Copepod Oithona nana Reveals the Development of a New Nervous Ganglion and Lin12-Notch-Repeat Protein-Associated Proteolysis. PMID:34356512
Parentage Analysis in Giant Grouper (Epinephelus lanceolatus) Using Microsatellite and SNP Markers from Genotyping-by-Sequencing Data. PMID:34356058
Whole exome sequencing, in silico and functional studies confirm the association of the GJB2 mutation p.Cys169Tyr with deafness and suggest a role for the TMEM59 gene in the hearing process. PMID:34354426
Evaluation of a high-throughput, cost-effective Illumina library preparation kit. PMID:34354114
Fast and accurate exhaustive higher-order epistasis search with BitEpi. PMID:34354094
Haplotype-resolved genome assembly and allele-specific gene expression in cultivated ginger. PMID:34354050
De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes. PMID:34353948
Large Drosophila germline piRNA clusters are evolutionarily labile and dispensable for transposon regulation. PMID:34352205
The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation. PMID:34351910
Recovery from heat shock requires the microRNA pathway in Caenorhabditis elegans. PMID:34351906
Reconstruction of Metagenome-Assembled Genomes from Aquaria. PMID:34351234
The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription. PMID:34350963
Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade. PMID:34350829
Genetic insights into biological mechanisms governing human ovarian ageing. PMID:34349265
A curated dataset of modern and ancient high-coverage shotgun human genomes. PMID:34349118
Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle. PMID:34348764
Spliceosomal component PRP-40 is a central regulator of microexon splicing. PMID:34348142
The COVIDome Explorer researcher portal. PMID:34348131
A Genome Doubling Event Reshapes Rice Morphology and Products by Modulating Chromatin Signatures and Gene Expression Profiling. PMID:34347189
Generalizable characteristics of false-positive bacterial variant calls. PMID:34346861
JAK inhibitors dampen activation of interferon-activated transcriptomes and the SARS-CoV-2 receptor ACE2 in human renal proximal tubules. PMID:34345808
Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients. PMID:34344959
SorGSD: updating and expanding the sorghum genome science database with new contents and tools. PMID:34344425
CLAMP and Zelda function together to promote Drosophila zygotic genome activation. PMID:34342574
Comprehensive Strain-Level Analysis of the Gut Microbe Faecalibacterium prausnitzii in Patients with Liver Cirrhosis. PMID:34342541
Catching SARS-CoV-2 by Sequence Hybridization: a Comparative Analysis. PMID:34342536
Identification and Differentiation of Pseudomonas Species in Field Samples Using an rpoD Amplicon Sequencing Methodology. PMID:34342531
Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin. PMID:34341563
The genomic epidemiology of multi-drug resistant invasive non-typhoidal Salmonella in selected sub-Saharan African countries. PMID:34341020
Clinical application of whole transcriptome sequencing for the classification of patients with acute lymphoblastic leukemia. PMID:34340673
High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING. PMID:34339413
Identification and fine genetic mapping of the golden pod gene (pv-ye) from the snap bean (Phaseolus vulgaris L.). PMID:34338807
Transcriptomic markers of fungal growth, respiration and carbon-use efficiency. PMID:34338746
Contrasting effects of Western vs Mediterranean diets on monocyte inflammatory gene expression and social behavior in a primate model. PMID:34338633
The Second Oncogenic Hit Determines the Cell Fate of ETV6-RUNX1 Positive Leukemia. PMID:34336858
An Exploratory Study for the Association of Gut Microbiome with Efficacy of Immune Checkpoint Inhibitor in Patients with Hepatocellular Carcinoma. PMID:34336726
Super-Enhancer Induced IL-20RA Promotes Proliferation/Metastasis and Immune Evasion in Colorectal Cancer. PMID:34336707
Complementary Sequential Circulating Tumor Cell (CTC) and Cell-Free Tumor DNA (ctDNA) Profiling Reveals Metastatic Heterogeneity and Genomic Changes in Lung Cancer and Breast Cancer. PMID:34336686
The best of both worlds: Combining lineage-specific and universal bait sets in target-enrichment hybridization reactions. PMID:34336398
EFSA statement on the requirements for whole genome sequence analysis of microorganisms intentionally used in the food chain. PMID:34335919
Whole Genome Sequencing Reveals Signatures for Artificial Selection for Different Sizes in Japanese Primitive Dog Breeds. PMID:34335687
Spatial and Ecological Drivers of Genetic Structure in Greek Populations of Alkanna tinctoria (Boraginaceae), a Polyploid Medicinal Herb. PMID:34335669
Heterophylly Quantitative Trait Loci Respond to Salt Stress in the Desert Tree Populus euphratica. PMID:34335660
Increased Virulence of Outer Membrane Porin Mutants of Mycobacterium abscessus. PMID:34335541
An Ecological Basis for Dual Genetic Code Expansion in Marine Deltaproteobacteria. PMID:34335502
The SRSF4-GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy. PMID:34333993
Genomic signatures of natural selection at phenology-related genes in a widely distributed tree species Fagus sylvatica L. PMID:34332553
CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN. PMID:34331859
FLEP-seq: simultaneous detection of RNA polymerase II position, splicing status, polyadenylation site and poly(A) tail length at genome-wide scale by single-molecule nascent RNA sequencing. PMID:34331052
Large-scale protein level comparison of Deltaproteobacteria reveals cohesive metabolic groups. PMID:34331018
Extensive variation in the intelectin gene family in laboratory and wild mouse strains. PMID:34330944
Cell-free reconstitution reveals the molecular mechanisms for the initiation of secondary siRNA biogenesis in plants. PMID:34330830
The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing. PMID:34330711
Variation p.R1045H in MYH7 correlated with hypertrophic cardiomyopathy in a Chinese pedigree. PMID:34330286
A chromosome-level genome assembly of Cairina moschata and comparative genomic analyses. PMID:34330207
Adaptive Introgression Facilitates Adaptation to High Latitudes in European Aspen (Populus tremula L.). PMID:34329481
Characterization of Penaeus vannamei mitogenome focusing on genetic diversity. PMID:34329352
Metagenomic analysis of primary colorectal carcinomas and their metastases identifies potential microbial risk factors. PMID:34328665
Phylogeography and resistome of pneumococcal meningitis in West Africa before and after vaccine introduction. PMID:34328412
Genomic Epidemiology and Transmission Dynamics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Congregate Healthcare Facilities in Santa Clara County, California. PMID:34328176
Whole-genome resequencing of Japanese whiting ( Sillago japonica) provide insights into local adaptations. PMID:34327887
A population-based genomic epidemiological study of the source of tuberculosis infections in an emerging city: Shenzhen, China. PMID:34327429
SpikChIP: a novel computational methodology to compare multiple ChIP-seq using spike-in chromatin. PMID:34327329
Co-expression network and comparative transcriptome analysis for fiber initiation and elongation reveal genetic differences in two lines from upland cotton CCRI70 RIL population. PMID:34327061
MutMap Approach Enables Rapid Identification of Candidate Genes and Development of Markers Associated With Early Flowering and Enhanced Seed Size in Chickpea (Cicer arietinum L.). PMID:34326857
Genomic Diversity of the Ostreid Herpesvirus Type 1 Across Time and Location and Among Host Species. PMID:34326830
Comparison of Two Aspergillus oryzae Genomes From Different Clades Reveals Independent Evolution of Alpha-Amylase Duplication, Variation in Secondary Metabolism Genes, and Differences in Primary Metabolism. PMID:34326825
An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer. PMID:34326322
A comprehensive approach for microbiota and health monitoring in mouse colonies using metagenomic shotgun sequencing. PMID:34325744
The role of neutral and adaptive genomic variation in population diversification and speciation in two ground squirrel species of conservation concern. PMID:34324748
MFGM components promote gut Bifidobacterium growth in infant and in vitro. PMID:34324046
Detection of SARS-CoV-2 variants by genomic analysis of wastewater samples in Israel. PMID:34323811
Genomic characterization of sporadic isolates of the dominant clone of Mycobacterium abscessus subspecies massiliense. PMID:34321532
The first draft genome of feather grasses using SMRT sequencing and its implications in molecular studies of Stipa. PMID:34321531
Characterization of the blood-brain barrier in genetically diverse laboratory mouse strains. PMID:34321020
Characterization of DNA lesions associated with cell-free DNA by targeted deep sequencing. PMID:34320984
Endogenous Retroviruses Drive Lineage-Specific Regulatory Evolution across Primate and Rodent Placentae. PMID:34320657
Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction. PMID:34320406
Chemical interplay and complementary adaptative strategies toggle bacterial antagonism and co-existence. PMID:34320359
Simultaneous Determination of Mycobacterium leprae Drug Resistance and Single-Nucleotide Polymorphism Genotype by Use of Nested Multiplex PCR with Amplicon Sequencing. PMID:34319800
High potency of sequential therapy with only β-lactam antibiotics. PMID:34318749
A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood. PMID:34318329
Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance. PMID:34316715
Actionability evaluation of biliary tract cancer by genome transcriptome analysis and Asian cancer knowledgebase. PMID:34316332
Genome of the pincer wasp Gonatopus flavifemur reveals unique venom evolution and a dual adaptation to parasitism and predation. PMID:34315471
Genomic signatures of rapid adaptive divergence in a tropical montane species. PMID:34314643
Landscape of tissue-specific RNA Editome provides insight into co-regulated and altered gene expression in pigs (Sus-scrofa). PMID:34314293
Discovering single nucleotide variants and indels from bulk and single-cell ATAC-seq. PMID:34313779
Deciphering Symbiotic Interactions of "Candidatus Aenigmarchaeota" with Inferred Horizontal Gene Transfers and Co-occurrence Networks. PMID:34313464
SARS-CoV-2 Restructures the Host Chromatin Architecture. PMID:34312624
Recent ultra-rare inherited variants implicate new autism candidate risk genes. PMID:34312540
Bottleneck size and selection level reproducibly impact evolution of antibiotic resistance. PMID:34312522
Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition. PMID:34310651
miRge3.0: a comprehensive microRNA and tRF sequencing analysis pipeline. PMID:34308351
Current production by non-methanotrophic bacteria enriched from an anaerobic methane-oxidizing microbial community. PMID:34308332
A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples. PMID:34308277
Southern introgression increases adaptive immune gene variability in northern range margin populations of Fire-bellied toad. PMID:34306661
Social environment and genetics underlie body site-specific microbiomes of Yellowstone National Park gray wolves (Canis lupus). PMID:34306636
Using bioinformatics approaches to investigate driver genes and identify BCL7A as a prognostic gene in colorectal cancer. PMID:34306573
Gonadotropin inhibitory hormone downregulates steroid hormone secretion and genes expressions in duck granulosa cells. PMID:34306216
Gene Loss, Pseudogenization in Plastomes of Genus Allium (Amaryllidaceae), and Putative Selection for Adaptation to Environmental Conditions. PMID:34306019
Thermosensitive sex chromosome dosage compensation in ZZ/ZW softshell turtles, Apalone spinifera. PMID:34304598
Sex-biased gene expression and recent sex chromosome turnover. PMID:34304591
RNA-Sequencing Analysis of Differentially Expressed Genes in Human iPSC-Derived Cardiomyocytes. PMID:34302660
Genomic evolution of antimicrobial resistance in Escherichia coli. PMID:34301966
Strainberry: automated strain separation in low-complexity metagenomes using long reads. PMID:34301928
Accelerated expansion of pathogenic mitochondrial DNA heteroplasmies in Huntington's disease. PMID:34301881
Sequencing of a central nervous system tumor demonstrates cancer transmission in an organ transplant. PMID:34301805
Genomic architecture constrained placental mammal X Chromosome evolution. PMID:34301625
BMI trajectory in childhood is associated with asthma incidence at young adulthood mediated by DNA methylation. PMID:34301314
The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border. PMID:34299796
Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis. PMID:34299025
CSNK1A1, KDM2A, and LTB4R2 Are New Druggable Vulnerabilities in Lung Cancer. PMID:34298691
The BET Inhibitor JQ1 Augments the Antitumor Efficacy of Gemcitabine in Preclinical Models of Pancreatic Cancer. PMID:34298684
A key antisense sRNA modulates the oxidative stress response and virulence in Xanthomonas oryzae pv. oryzicola. PMID:34297775
Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang. PMID:34297769
The genome of the Pyrenean desman and the effects of bottlenecks and inbreeding on the genomic landscape of an endangered species. PMID:34295371
Genomic data support management of anadromous Arctic Char fisheries in Nunavik by highlighting neutral and putatively adaptive genetic variation. PMID:34295370
Movements of transposable elements contribute to the genomic plasticity and species diversification in an asexually reproducing nematode pest. PMID:34295368
Natural CO2 seeps reveal adaptive potential to ocean acidification in fish. PMID:34295364
Determinants of Persistent Patterns of Pepino Mosaic Virus Mixed Infections. PMID:34295323
Hybrid Genome Assembly for Predicting Functional Potential of a Novel Streptomyces Strain as Plant Biomass Valorisation Agent. PMID:34294994
Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells. PMID:34294917
Genomics accelerated isolation of a new stem rust avirulence gene-wheat resistance gene pair. PMID:34294906
Genome of the world's smallest flowering plant, Wolffia australiana, helps explain its specialized physiology and unique morphology. PMID:34294872
Harmful R-loops are prevented via different cell cycle-specific mechanisms. PMID:34294712
Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis. PMID:34294701
A minus-end directed kinesin motor directs gravitropism in Physcomitrella patens. PMID:34294690
Genomic analysis of field pennycress (Thlaspi arvense) provides insights into mechanisms of adaptation to high elevation. PMID:34294107
Retinoblastoma genetics screening and clinical management. PMID:34294096
Fine dissection of limber pine resistance to Cronartium ribicola using targeted sequencing of the NLR family. PMID:34294045
The complete mitochondrial genome of Cycas debaoensis revealed unexpected static evolution in gymnosperm species. PMID:34293066
Identification of microRNA-like RNAs from Trichoderma asperellum DQ-1 during its interaction with tomato roots using bioinformatic analysis and high-throughput sequencing. PMID:34293017
Induction of a chromatin boundary in vivo upon insertion of a TAD border. PMID:34292939
Complete Genome Sequence of a Bacteroides fragilis Bacteriophage, vB_BfrS_NCTC. PMID:34292066
The complete mitochondrial genome of Trissolcus japonicus (Hymenoptera: Scelionidae), the candidate for the biological control of Halyomorpha halys (Hemiptera: Pentatomidae). PMID:34291166
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer. PMID:34290255
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy. PMID:34289358
RHOX10 drives mouse spermatogonial stem cell establishment through a transcription factor signaling cascade. PMID:34289349
Balancing Selection for Pathogen Resistance Reveals an Intercontinental Signature of Red Queen Coevolution. PMID:34289047
Molecular epidemiology of SARS-CoV-2 in Cyprus. PMID:34288921
Whole-genome analysis of TET dioxygenase function in regulatory T cells. PMID:34288360
Intragenic Distribution of IS6110 in Clinical Mycobacterium tuberculosis Strains: Bioinformatic Evidence for Gene Disruption Leading to Underdiagnosed Antibiotic Resistance. PMID:34287057
Amplicon and Metagenomic Analysis of Middle East Respiratory Syndrome (MERS) Coronavirus and the Microbiome in Patients with Severe MERS. PMID:34287009
RNA Sequencing of CD4+ T Cells in Relapsing-Remitting Multiple Sclerosis Patients at Relapse: Deciphering the Involvement of Novel genes and Pathways. PMID:34286457
ChIP-seq Experiment and Data Analysis in the Cyanobacterium Synechocystis sp. PCC 6803. PMID:34286004
A combined GWAS approach reveals key loci for socially-affected traits in Yorkshire pigs. PMID:34285319
Temperature heterogeneity correlates with intraspecific variation in physiological flexibility in a small endotherm. PMID:34285216
Non-coding RNAs in the interaction between rice and Meloidogyne graminicola. PMID:34284724
Genome-wide association screening and verification of potential genes associated with root architectural traits in maize (Zea mays L.) at multiple seedling stages. PMID:34284723
Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing. PMID:34284719
Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts. PMID:34284202
Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity. PMID:34284134
Unraveling the genetics of tomato fruit weight during crop domestication and diversification. PMID:34283260
Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state. PMID:34283254
Pursuit of Gene Fusions in Daily Practice: Evidence from Real-World Data in Wild-Type and Microsatellite Instable Patients. PMID:34282766
A plate-based single-cell ATAC-seq workflow for fast and robust profiling of chromatin accessibility. PMID:34282334
BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells. PMID:34282330
Metagenomic identification of a new sarbecovirus from horseshoe bats in Europe. PMID:34282196
A deep learning model for predicting next-generation sequencing depth from DNA sequence. PMID:34282137
Haploflow: strain-resolved de novo assembly of viral genomes. PMID:34281604
Comparative and functional genomics of the ABC transporter superfamily across arthropods. PMID:34281528
Identification of QTL related to anther color and hull color by RAD sequencing in a RIL population of Setaria italica. PMID:34281524
Dynamic Colonization of Microbes and Their Functions after Fecal Microbiota Transplantation for Inflammatory Bowel Disease. PMID:34281401
The Interspecific Fungal Hybrid Verticillium longisporum Displays Subgenome-Specific Gene Expression. PMID:34281400
Comparative Transcriptome Analysis Reveals Genetic Mechanisms of Sugarcane Aphid Resistance in Grain Sorghum. PMID:34281180
scDPN for High-throughput Single-cell CNV Detection to Uncover Clonal Evolution During HCC Recurrence. PMID:34280548
Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling. PMID:34280251
Characterization of Chromatin Accessibility and Gene Expression upon Cold Stress Reveals that the RAV1 Transcription Factor Functions in Cold Response in Vitis Amurensis. PMID:34279666
Structure-guided microbial targeting of antistaphylococcal prodrugs. PMID:34279224
High-resolution, genome-wide mapping of positive supercoiling in chromosomes. PMID:34279217
Highly contiguous assemblies of 101 drosophilid genomes. PMID:34279216
Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice. PMID:34278710
Mutation profiling of a limbless pig reveals genome-wide regulation of RNA processing related to bone development. PMID:34278546
NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells. PMID:34278268
The effects of aging on molecular modulators of human embryo implantation. PMID:34278260
The strand-biased transcription of SARS-CoV-2 and unbalanced inhibition by remdesivir. PMID:34278249
Dual-Specificity Phosphatase 9 Regulates Cellular Proliferation and Predicts Recurrence After Surgery in Hepatocellular Carcinoma. PMID:34278178
Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2. PMID:34276797
Unraveling Genetic Diversity Amongst European Hazelnut (Corylus avellana L.) Varieties in Turkey. PMID:34276724
Large Differences in the Haptophyte Phaeocystis globosa Mitochondrial Genomes Driven by Repeat Amplifications. PMID:34276607
Whole Genome-Based Characterization of Listeria monocytogenes Isolates Recovered From the Food Chain in South Africa. PMID:34276601
HAVoC, a bioinformatic pipeline for reference-based consensus assembly and lineage assignment for SARS-CoV-2 sequences. PMID:34273961
The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo. PMID:34272393
Large-scale whole-genome resequencing unravels the domestication history of Cannabis sativa. PMID:34272249
FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure. PMID:34272244
Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models. PMID:34271981
The genetic architecture of temperature adaptation is shaped by population ancestry and not by selection regime. PMID:34271951
Molecular characteristics and clinical outcomes of complex ALK rearrangements identified by next-generation sequencing in non-small cell lung cancers. PMID:34271921
First detection and molecular analysis of SARS-CoV-2 from a naturally infected cat from Argentina. PMID:34271305
Toward genomic selection in Pinus taeda: Integrating resources to support array design in a complex conifer genome. PMID:34268018
Genome-Wide Association Mapping of bc-1 and bc-u Reveals Candidate Genes and New Adjustments to the Host-Pathogen Interaction for Resistance to Bean Common Mosaic Necrosis Virus in Common Bean. PMID:34267774
Nationwide genomic atlas of soil-dwelling Listeria reveals effects of selection and population ecology on pangenome evolution. PMID:34267358
Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identify disease-relevant transcripts containing G-rich motifs. PMID:34266995
Coding-Complete Genome Sequences of 11 SARS-CoV-2 B.1.1.7 and B.1.351 Variants from Metro Manila, Philippines. PMID:34264104
Complete chloroplast genome of Eucampia zodiacus (Mediophyceae, Bacillariophyta). PMID:34263048
The complete mitochondrial genome of the wood tiger moth (Arctia plantaginis) and phylogenetic analyses within Arctiinae. PMID:34263042
A Cluster-Based Approach for the Discovery of Copy Number Variations From Next-Generation Sequencing Data. PMID:34262604
Fine Mapping and Candidate Gene Identification for the CapUp Locus Controlling Fruit Orientation in Pepper (Capsicum spp.). PMID:34262581
Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples. PMID:34261731
Haplotype-resolved germline and somatic alterations in renal medullary carcinomas. PMID:34261517
A novel class III endogenous retrovirus with a class I envelope gene in African frogs with an intact genome and developmentally regulated transcripts in Xenopus tropicalis. PMID:34261506
Genomic surveillance of antimicrobial resistant bacterial colonisation and infection in intensive care patients. PMID:34261450
Analysis of H3K4me3-ChIP-Seq and RNA-Seq data to understand the putative role of miRNAs and their target genes in breast cancer cell lines. PMID:34261302
Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs. PMID:34260908
Genome Sequences of Two Pseudomonas aeruginosa Isolates with Defects in Type III Secretion System Gene Expression from a Chronic Ankle Wound Infection. PMID:34259549
HBO1 is a versatile histone acyltransferase critical for promoter histone acylations. PMID:34259319
A Trimethylguanosine Synthase1-like (TGS1) homologue is implicated in vernalisation and flowering time control. PMID:34258645
Protocol for using TRIBE to study RNA-protein interactions and nuclear organization in mammalian cells. PMID:34258595
Comparative analysis of clonal evolution among patients with right- and left-sided colon and rectal cancer. PMID:34258553
A Noninvasive Multianalytical Approach for Lung Cancer Diagnosis of Patients with Pulmonary Nodules. PMID:34258160
Arabidopsis MORC proteins function in the efficient establishment of RNA directed DNA methylation. PMID:34257299
DNA transposons mediate duplications via transposition-independent and -dependent mechanisms in metazoans. PMID:34257290
Validation of a novel associative transcriptomics pipeline in Brassica oleracea: identifying candidates for vernalisation response. PMID:34256693
Genome sequence of Apostasia ramifera provides insights into the adaptive evolution in orchids. PMID:34256691
Genome-scale sequencing and analysis of human, wolf, and bison DNA from 25,000-year-old sediment. PMID:34256019
A duplicated amh is the master sex-determining gene for Sebastes rockfish in the Northwest Pacific. PMID:34255977
HPV transcript expression affects cervical cancer response to chemoradiation. PMID:34255749
Whole-genome re-sequencing association study on yearling wool traits in Chinese fine-wool sheep. PMID:34255028
Highly Replicated Evolution of Parapatric Ecotypes. PMID:34254128
Chromosome-scale genome assembly of the transformation-amenable common wheat cultivar 'Fielder'. PMID:34254113
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration. PMID:34253898
The Welwitschia genome reveals a unique biology underpinning extreme longevity in deserts. PMID:34253727
Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis. PMID:34253709
FLAME: long-read bioinformatics tool for comprehensive spliceome characterization. PMID:34253685
Telomere-to-telomere assembly of a fish Y chromosome reveals the origin of a young sex chromosome pair. PMID:34253240
GRIDSS2: comprehensive characterisation of somatic structural variation using single breakend variants and structural variant phasing. PMID:34253237
Whole genome sequencing identifies novel structural variant in a large Indian family affected with X-linked agammaglobulinemia. PMID:34252140
Essential gene acquisition destabilizes plasmid inheritance. PMID:34252089
Genome mapping coupled with CRISPR gene editing reveals a P450 gene confers avermectin resistance in the beet armyworm. PMID:34252082
Global transcriptome analysis of Stenotrophomonas maltophilia in response to growth at human body temperature. PMID:34252021
Quantitative trait loci for growth-related traits in Japanese quail (Coturnix japonica) using restriction-site associated DNA sequencing. PMID:34251529
Target enrichment improves phylogenetic resolution in the genus Zanthoxylum (Rutaceae) and indicates both incomplete lineage sorting and hybridization events. PMID:34250543
Polysomal mRNA Association and Gene Expression in Trypanosoma brucei. PMID:34250262
The complete plastome sequence of Pinellia peltata Pei (Araceae). PMID:34250233
Dysbiotic gut microbiota in pancreatic cancer patients form correlation networks with the oral microbiota and prognostic factors. PMID:34249452
Putative Causal Variants Are Enriched in Annotated Functional Regions From Six Bovine Tissues. PMID:34249087
Genetic Divergence and Population Structure in Weedy and Cultivated Broomcorn Millets (Panicum miliaceum L.) Revealed by Specific-Locus Amplified Fragment Sequencing (SLAF-Seq). PMID:34249058
E183K Mutation in Chalcone Synthase C2 Causes Protein Aggregation and Maize Colorless. PMID:34249050
The Effects of Herbarium Specimen Characteristics on Short-Read NGS Sequencing Success in Nearly 8000 Specimens: Old, Degraded Samples Have Lower DNA Yields but Consistent Sequencing Success. PMID:34249041
Whole-Genome Metagenomic Analysis of the Gut Microbiome in HIV-1-Infected Individuals on Antiretroviral Therapy. PMID:34248876
Resequencing and transcriptomic analysis reveal differences in nitrite reductase in jujube fruit (Ziziphus jujuba Mill.). PMID:34247631
A 180 Myr-old female-specific genome region in sturgeon reveals the oldest known vertebrate sex determining system with undifferentiated sex chromosomes. PMID:34247507
Diploidy within a Haploid Genus of Entomopathogenic Fungi. PMID:34247231
Transcriptomal dissection of soybean circadian rhythmicity in two geographically, phenotypically and genetically distinct cultivars. PMID:34246232
Single-oocyte transcriptome analysis reveals aging-associated effects influenced by life stage and calorie restriction. PMID:34245092
RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners. PMID:34244793
New insights into the evolution of human Y chromosome palindromes through mutation and gene conversion. PMID:34244762
An isoform of Dicer protects mammalian stem cells against multiple RNA viruses. PMID:34244417
Genome-wide mapping reveals R-loops associated with centromeric repeats in maize. PMID:34244230
A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies. PMID:34242585
Cross-species Exon Capture and Whole Exome Sequencing: Application, Utility and Challenges for Genomic Resource Development in Non-model Species. PMID:34241713
Whole-genome resequencing of 240 Gossypium barbadense accessions reveals genetic variation and genes associated with fiber strength and lint percentage. PMID:34240238
Rapid Evolution of Complete Dosage Compensation in Poecilia. PMID:34240180
Deciphering the effects of PYCR1 on cell function and its associated mechanism in hepatocellular carcinoma. PMID:34239351
MaxDIA enables library-based and library-free data-independent acquisition proteomics. PMID:34239088
TMEM263: a novel candidate gene implicated in human autosomal recessive severe lethal skeletal dysplasia. PMID:34238371
MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean. PMID:34236584
Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis. PMID:34236313
Metagenome-Assembled Genome Sequences from Different Wastewater Treatment Stages in Germany. PMID:34236226
Complete Genome Sequences of the Methicillin-Resistant Strain Staphylococcus aureus 17Gst354 and Its Prophage Staphylococcus Phage vB_StaphS-IVBph354. PMID:34236219
Identification and Characterization of Mycobacterial Species Using Whole-Genome Sequences. PMID:34235665
Differential ATAC-seq and ChIP-seq peak detection using ROTS. PMID:34235431
The New Is Old: Novel Germination Strategy Evolved From Standing Genetic Variation in Weedy Rice. PMID:34234803
Maize Inbred Line B96 Is the Source of Large-Effect Loci for Resistance to Generalist but Not Specialist Spider Mites. PMID:34234802
A Novel SARS-CoV-2 Viral Sequence Bioinformatic Pipeline Has Found Genetic Evidence That the Viral 3' Untranslated Region (UTR) Is Evolving and Generating Increased Viral Diversity. PMID:34234758
Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae. PMID:34234279
SPP1 overexpression is associated with poor outcomes in ALK fusion lung cancer patients without receiving targeted therapy. PMID:34234236
The first insight into the genetic structure of the population of modern Serbia. PMID:34234178
Translocation of vaginal microbiota is involved in impairment and protection of uterine health. PMID:34234149
GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health. PMID:34234147
Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis. PMID:34234141
M1BP cooperates with CP190 to activate transcription at TAD borders and promote chromatin insulator activity. PMID:34234130
Deep learning prediction of attention-deficit hyperactivity disorder in African Americans by copy number variation. PMID:34233526
Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. PMID:34233187
Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations. PMID:34233005
Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Stage Transition under Temperature Stress in Synchronized Plasmodium falciparum Cells. PMID:34232098
Optical genome mapping identifies a germline retrotransposon insertion in SMARCB1 in two siblings with atypical teratoid rhabdoid tumors. PMID:34231212
Integrative analysis of genomic and epigenomic data reveal underlying superenhancer-mediated microRNA regulatory network for human bone mineral density. PMID:34230965
Sequencing SARS-CoV-2 Genomes from Saliva. PMID:34230934
The mitochondrial genome of the grape powdery mildew pathogen Erysiphe necator is intron rich and exhibits a distinct gene organization. PMID:34230575
Metagenomic analysis of a throat swab sample collected in China on a patient infected with Varicella Zoster Virus. PMID:34230529
Pervasive transcription of the mitochondrial genome in Candida albicans is revealed in mutants lacking the mtEXO RNase complex. PMID:34229573
A comparison of metabolic labeling and statistical methods to infer genome-wide dynamics of RNA turnover. PMID:34228787
Burden of Cardiomyopathic Genetic Variation in Lethal Pediatric Myocarditis. PMID:34228484
PaintSHOP enables the interactive design of transcriptome- and genome-scale oligonucleotide FISH experiments. PMID:34226720
Sequencing an F1 hybrid of Silurus asotus and S. meridionalis enabled the assembly of high-quality parental genomes. PMID:34226617
Four chromosome scale genomes and a pan-genome annotation to accelerate pecan tree breeding. PMID:34226565
Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response. PMID:34225752
Integration of transcriptomic data identifies key hallmark genes in hypertrophic cardiomyopathy. PMID:34225646
Replication Dynamics for Six Gram-Negative Bacterial Species during Bloodstream Infection. PMID:34225485
Selective digestive decontamination with oral colistin plus gentamicin for persistent bacteraemia caused by non-carbapenemase-producing carbapenem-resistant Klebsiella pneumoniae in a neutropenic patient. PMID:34223138
The emergence of azithromycin-resistant Salmonella Typhi in Nepal. PMID:34223059
Genome Wide Prediction, Mapping and Development of Genomic Resources of Mastitis Associated Genes in Water Buffalo. PMID:34222390
Identifying Potential Neoantigens for Cervical Cancer Immunotherapy Using Comprehensive Genomic Variation Profiling of Cervical Intraepithelial Neoplasia and Cervical Cancer. PMID:34221990
Genomic Analysis Reveals Human-Mediated Introgression From European Commercial Pigs to Henan Indigenous Pigs. PMID:34220966
Nanopore and Illumina Genome Sequencing of Fusarium oxysporum f. sp. lini Strains of Different Virulence. PMID:34220940
Pooled Sequencing Analysis of Geese (Anser cygnoides) Reveals Genomic Variations Associated With Feather Color. PMID:34220935
Successful ATAC-Seq From Snap-Frozen Equine Tissues. PMID:34220931
Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits. PMID:34220925
The Distribution and Origins of Pyrus hopeiensis-"Wild Plant With Tiny Population" Using Whole Genome Resequencing. PMID:34220890
Deadwood-Inhabiting Bacteria Show Adaptations to Changing Carbon and Nitrogen Availability During Decomposition. PMID:34220772
Two decades of one health surveillance of Nipah virus in Thailand. PMID:34218820
Genome sequencing identified novel mechanisms underlying virescent mutation in upland cotton Gossypiuma hirsutum. PMID:34217203
Targeted long-read sequencing identifies missing disease-causing variation. PMID:34216551
Polyamine metabolism is a central determinant of helper T cell lineage fidelity. PMID:34216540
Genetic and phylogenetic analysis of dissimilatory iodate-reducing bacteria identifies potential niches across the world's oceans. PMID:34215855
Reprogramming of the wheat transcriptome in response to infection with Claviceps purpurea, the causal agent of ergot. PMID:34215204
The genetic basis of adaptation in phenology in an introduced population of Black Cottonwood (Populus trichocarpa, Torr. & Gray). PMID:34215191
Pheniqs 2.0: accurate, high-performance Bayesian decoding and confidence estimation for combinatorial barcode indexing. PMID:34215187
A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis. PMID:34215186
Female-specific genomic regions and molecular sex identification of the clearhead icefish (Protosalanx hyalocranius). PMID:34215185
De novo transcriptome analysis of white teak (Gmelina arborea Roxb) wood reveals critical genes involved in xylem development and secondary metabolism. PMID:34215181
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy. PMID:34214472
A sensitive repeat identification framework based on short and long reads. PMID:34214175
ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions. PMID:34214142
Characterization of a novel transitional group Rickettsia species (Rickettsia tillamookensis sp. nov.) from the western black-legged tick, Ixodes pacificus. PMID:34214027
A Comparative Analyses of the Complete Mitochondrial Genomes of Fungal Endosymbionts in Sogatella furcifera, White-Backed Planthoppers. PMID:34212028
Dual infection and recombination of Kaposi sarcoma herpesvirus revealed by whole-genome sequence analysis of effusion samples. PMID:34211736
Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq. PMID:34211161
Targeted base editing in the plastid genome of Arabidopsis thaliana. PMID:34211131
Clinical characteristics and genetic spectrum of 26 individuals of Chinese origin with primary ciliary dyskinesia. PMID:34210339
Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway. PMID:34210294
Deleterious Mutations in the TPO Gene Associated with Familial Thyroid Follicular Cell Carcinoma in Dutch German Longhaired Pointers. PMID:34209805
Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer's Disease Risk Reveal a Potential Role for SIGLEC14. PMID:34208838
How a Paleogenomic Approach Can Provide Details on Bioarchaeological Reconstruction: A Case Study from the Globular Amphorae Culture. PMID:34208224
A Comprehensive Molecular Epidemiological Analysis of SARS-CoV-2 Infection in Cyprus from April 2020 to January 2021: Evidence of a Highly Polyphyletic and Evolving Epidemic. PMID:34207490
Comprehensive Evolutionary Analysis of Complete Epstein-Barr Virus Genomes from Argentina and Other Geographies. PMID:34207433
A DNA Regulatory Element Haplotype at Zinc Finger Genes Is Associated with Host Resilience to Small Ruminant Lentivirus in Two Sheep Populations. PMID:34206933
Pincho: A Modular Approach to High Quality De Novo Transcriptomics. PMID:34206353
Nearly Identical Plasmids Encoding VIM-1 and Mercury Resistance in Enterobacteriaceae from North-Eastern Germany. PMID:34206177
QTL Analysis of Stem Elongation and Flowering Time in Lettuce Using Genotyping-by-Sequencing. PMID:34205694
A Global Landscape of Miniature Inverted-Repeat Transposable Elements in the Carrot Genome. PMID:34205210
Satellitome Analysis of Rhodnius prolixus, One of the Main Chagas Disease Vector Species. PMID:34205189
mTOR Driven Gene Transcription Is Required for Cholesterol Production in Neurons of the Developing Cerebral Cortex. PMID:34204880
Evaluation of Oxford Nanopore MinION RNA-Seq Performance for Human Primary Cells. PMID:34204756
Next Generation Cytogenetics in Myeloid Hematological Neoplasms: Detection of CNVs and Translocations. PMID:34203905
Mitogenomes Reveal Two Major Influxes of Papuan Ancestry across Wallacea Following the Last Glacial Maximum and Austronesian Contact. PMID:34202821
TASPERT: Target-Specific Reverse Transcript Pools to Improve HTS Plant Virus Diagnostics. PMID:34202758
Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma. PMID:34202390
CIRCNV: Detection of CNVs Based on a Circular Profile of Read Depth from Sequencing Data. PMID:34202028
Insights into Autotrophic Activities and Carbon Flow in Iron-Rich Pelagic Aggregates (Iron Snow). PMID:34201891
Transcriptome Profiling of Starvation in the Peripheral Chemosensory Organs of the Crop Pest Spodoptera littoralis Caterpillars. PMID:34201462
What Goes Wrong during Early Development of Artificially Reproduced European Eel Anguilla anguilla? Clues from the Larval Transcriptome and Gene Expression Patterns. PMID:34201077
Comparative Genomics of Eight Fusarium graminearum Strains with Contrasting Aggressiveness Reveals an Expanded Open Pangenome and Extended Effector Content Signatures. PMID:34200775
Comparative Transcriptome Analysis Reveals Sex-Based Differences during the Development of the Adult Parasitic Wasp Cotesia vestalis (Hymenoptera: Braconidae). PMID:34200644
Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster. PMID:34200621
Pharmacological Inhibition of CBP/p300 Blocks Estrogen Receptor Alpha (ERα) Function through Suppressing Enhancer H3K27 Acetylation in Luminal Breast Cancer. PMID:34199844
Global mRNA and miRNA Analysis Reveal Key Processes in the Initial Response to Infection with WSSV in the Pacific Whiteleg Shrimp. PMID:34199268
Transcription factor RFX7 governs a tumor suppressor network in response to p53 and stress. PMID:34197623
Pax7 pioneer factor action requires both paired and homeo DNA binding domains. PMID:34197620
Efficient multiplexed gene regulation in Saccharomyces cerevisiae using dCas12a. PMID:34197613
Harnessing self-labeling enzymes for selective and concurrent A-to-I and C-to-U RNA base editing. PMID:34197596
Using Plasmodium knowlesi as a model for screening Plasmodium vivax blood-stage malaria vaccine targets reveals new candidates. PMID:34197567
Profiling DNA break sites and transcriptional changes in response to contextual fear learning. PMID:34197463
NPSV: A simulation-driven approach to genotyping structural variants in whole-genome sequencing data. PMID:34195837
Plastome and phylogenetic relationship of the woody buckwheat Fagopyrum tibeticum in the Qinghai-Tibet Plateau. PMID:34195504
Rapid Evolution of Autosomal Binding Sites of the Dosage Compensation Complex in Drosophila melanogaster and Its Association With Transcription Divergence. PMID:34194473
New Sources of Eastern Filbert Blight Resistance and Simple Sequence Repeat Markers on Linkage Group 6 in Hazelnut (Corylus avellana L.). PMID:34194458
Construction of a High-Density Genetic Map and Identification of Leaf Trait-Related QTLs in Chinese Bayberry (Myrica rubra). PMID:34194452
Genomic Analysis of Enterococcus spp. Isolated From a Wastewater Treatment Plant and Its Associated Waters in Umgungundlovu District, South Africa. PMID:34194401
HLA-DR Marks Recently Divided Antigen-Specific Effector CD4 T Cells in Active Tuberculosis Patients. PMID:34193602
Cytoplasmic long noncoding RNAs are differentially regulated and translated during human neuronal differentiation. PMID:34193551
Temporal dynamics of teleost populations during the Pleistocene: a report from publicly available genome data. PMID:34193045
Prevalence and polymorphism of a mussel transmissible cancer in Europe. PMID:34192383
A CRISPR-based assay for the study of eukaryotic DNA repair onboard the International Space Station. PMID:34191829
Human mobility at Tell Atchana (Alalakh), Hatay, Turkey during the 2nd millennium BC: Integration of isotopic and genomic evidence. PMID:34191795
Living to the High Extreme: Unraveling the Composition, Structure, and Functional Insights of Bacterial Communities Thriving in the Arsenic-Rich Salar de Huasco Altiplanic Ecosystem. PMID:34190603
Protocol for using heterologous spike-ins to normalize for technical variation in chromatin immunoprecipitation. PMID:34189474
Genome-wide mapping of DNA double-strand breaks from eukaryotic cell cultures using Break-seq. PMID:34189468
Novel allele elh of the UBP14 gene affects plant organ size via cell expansion in Arabidopsis thaliana. PMID:34189424
Augur: a bioinformatics toolkit for phylogenetic analyses of human pathogens. PMID:34189396
Stepwise target controllability identifies dysregulations of macrophage networks in multiple sclerosis. PMID:34189368
Genetic diversity and evolutionary patterns of Taraxacum kok-saghyz Rodin. PMID:34188861
The assembly of caprine Y chromosome sequence reveals a unique paternal phylogenetic pattern and improves our understanding of the origin of domestic goat. PMID:34188851
Comparative transcriptomics of albino and warningly-coloured caterpillars. PMID:34188830
Divergence and introgression in small apes, the genus Hylobates, revealed by reduced representation sequencing. PMID:34188193
Phylogenomics illuminates the evolution of bobtail and bottletail squid (order Sepiolida). PMID:34188187
Unraveling regulatory divergence, heterotic malleability, and allelic imbalance switching in rice due to drought stress. PMID:34188147
The m6A landscape of polyadenylated nuclear (PAN) RNA and its related methylome in the context of KSHV replication. PMID:34187903
The zinc finger protein CLAMP promotes long-range chromatin interactions that mediate dosage compensation of the Drosophila male X-chromosome. PMID:34187599
Evolution of mouse circadian enhancers from transposable elements. PMID:34187518
Frequent gain- and loss-of-function mutations of the BjMYB113 gene accounted for leaf color variation in Brassica juncea. PMID:34187365
Genetic and gene expression analysis of flowering time regulation by light quality in lentil. PMID:34185828
Epigenetic inheritance of DNA methylation changes in fish living in hydrogen sulfide-rich springs. PMID:34185679
C/EBPδ drives key endocrine signals in the human amnion at parturition. PMID:34185432
IFIH1 loss-of-function variants contribute to very early-onset inflammatory bowel disease. PMID:34185153
The Chromosome-Level Genome of Triplophysa dalaica (Cypriniformes: Cobitidae) Provides Insights into Its Survival in Extremely Alkaline Environment. PMID:34185063
Emergence of the novel SARS-CoV-2 lineage VUI-NP13L and massive spread of P.2 in South Brazil. PMID:34184973
Ecophysiology of the Cosmopolitan OM252 Bacterioplankton (Gammaproteobacteria). PMID:34184914
Mosaic Ends Tagmentation (METa) Assembly for Highly Efficient Construction of Functional Metagenomic Libraries. PMID:34184912
METAnnotatorX2: a Comprehensive Tool for Deep and Shallow Metagenomic Data Set Analyses. PMID:34184911
Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness. PMID:34183853
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells. PMID:34183817
COVID-19 mRNA vaccine induced antibody responses against three SARS-CoV-2 variants. PMID:34183681
Enhanced mutualistic symbiosis between soil phages and bacteria with elevated chromium-induced environmental stress. PMID:34183048
Gene expression analysis in EBV-infected ataxia-telangiectasia cell lines by RNA-sequencing reveals protein synthesis defect and immune abnormalities. PMID:34183044
Identification of a High-Frequency Intrahost SARS-CoV-2 Spike Variant with Enhanced Cytopathic and Fusogenic Effects. PMID:34182784
Cell-free genomics reveal intrinsic, cooperative and competitive determinants of chromatin interactions. PMID:34181732
AP-1 activity is a major barrier of human somatic cell reprogramming. PMID:34181046
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells. PMID:34180951
A multisite genomic epidemiology study of Clostridioides difficile infections in the USA supports differential roles of healthcare versus community spread for two common strains. PMID:34180789
The complete chloroplast genome sequence of new species candidate of Plantago depressa Willd. in Korea (Plantaginaceae). PMID:34179481
The complete chloroplast genome of Chrysanthemum zawadskii Herbich (Asteraceae) isolated in Korea. PMID:34179479
The complete mitochondrial genome of Ripeacma umbellata Wang, 2009 (Lepidoptera: Autostichidae). PMID:34179464
Comparative Epigenomics Reveals Host Diversity of the Trichinella Epigenomes and Their Effects on Differential Parasitism. PMID:34179010
Correlation Between Circulating Tumor Cell DNA Genomic Alterations and Mesenchymal CTCs or CTC-Associated White Blood Cell Clusters in Hepatocellular Carcinoma. PMID:34178679
Leveraging genomics to understand threats to migratory birds. PMID:34178110
Whole genome genotyping reveals discrete genetic diversity in north-east Atlantic maerl beds. PMID:34178104
Genetic load has potential in large populations but is realized in small inbred populations. PMID:34178103
Insights Into the Mechanisms Implicated in Pinus pinaster Resistance to Pinewood Nematode. PMID:34178007
Transcriptome-Wide Analysis of RNA m6A Methylation and Gene Expression Changes Among Two Arabidopsis Ecotypes and Their Reciprocal Hybrids. PMID:34178005
Ecological Divergence Within the Enterobacterial Genus Sodalis: From Insect Symbionts to Inhabitants of Decomposing Deadwood. PMID:34177846
Heterogeneous Streptomycin Resistance Level Among Mycobacterium tuberculosis Strains From the Same Transmission Cluster. PMID:34177837
HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples. PMID:34175494
Advancing clinical genomics and precision medicine with GVViZ: FAIR bioinformatics platform for variable gene-disease annotation, visualization, and expression analysis. PMID:34174938
Construction of a high-density linkage map and graphical representation of the arrangement of transcriptome-based unigene markers on the chromosomes of onion, Allium cepa L. PMID:34174821
Neither Donor nor Recipient Mitochondrial Haplotypes Are Associated with Unrelated Donor Transplant Outcomes: A Validation Study from the CIBMTR. PMID:34174468
Single-cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions. PMID:34173975
Immunogenomic profiling and pathological response results from a clinical trial of docetaxel and carboplatin in triple-negative breast cancer. PMID:34173924
A de novo transcriptional atlas in Danaus plexippus reveals variability in dosage compensation across tissues. PMID:34172835
Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring. PMID:34172814
SCAPP: an algorithm for improved plasmid assembly in metagenomes. PMID:34172093
Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation. PMID:34169237
DIVIS: Integrated and Customizable Pipeline for Cancer Genome Sequencing Analysis and Interpretation. PMID:34168993
St. Louis Encephalitis Virus in the Southwestern United States: A Phylogeographic Case for a Multi-Variant Introduction Event. PMID:34168675
Characterization of Japanese Plum (Prunus salicina) PsMYB10 Alleles Reveals Structural Variation and Polymorphisms Correlating With Fruit Skin Color. PMID:34168666
Memory CD8 T Cells Generated by Cytomegalovirus Vaccine Vector Expressing NKG2D Ligand Have Effector-Like Phenotype and Distinct Functional Features. PMID:34168650
Genome-scale comparative analysis for host resistance against sea lice between Atlantic salmon and rainbow trout. PMID:34168167
Nuclear ADP-ribosylation drives IFNγ-dependent STAT1α enhancer formation in macrophages. PMID:34168143
Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication. PMID:34168039
Genome-wide profiling reveals functional interplay of DNA sequence composition, transcriptional activity, and nucleosome positioning in driving DNA supercoiling and helix destabilization in C. elegans. PMID:34168009
Fusarium head blight resistance in European winter wheat: insights from genome-wide transcriptome analysis. PMID:34167474
Genetic architecture of transmission stage production and virulence in schistosome parasites. PMID:34167443
Evaluating coverage bias in next-generation sequencing of Escherichia coli. PMID:34166413
Chromosome-Scale Genome Assembly of the Resurrection Plant Acanthochlamys bracteata (Velloziaceae). PMID:34165527
SplitStrains, a tool to identify and separate mixed Mycobacterium tuberculosis infections from WGS data. PMID:34165419
Complete Genome Sequence of a Canadian Strain of Raoultella planticola with Metal and Antimicrobial Resistance Genes. PMID:34165338
HBOS-CNV: A New Approach to Detect Copy Number Variations From Next-Generation Sequencing Data. PMID:34163521
Agro-Morphological, Yield, and Genotyping-by-Sequencing Data of Selected Wheat (Triticum aestivum) Germplasm From Pakistan. PMID:34163518
Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome. PMID:34162892
COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillance. PMID:34162869
Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish. PMID:34162866
Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemur Megaladapis edwardsi. PMID:34162703
Genomic evidence for the Chinese mountain cat as a wildcat conspecific (Felis silvestris bieti) and its introgression to domestic cats. PMID:34162544
RUNX1-mediated alphaherpesvirus-host trans-species chromatin interaction promotes viral transcription. PMID:34162542
The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies. PMID:34161776
Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons. PMID:34161768
Soil metabolome response to whole-ecosystem warming at the Spruce and Peatland Responses under Changing Environments experiment. PMID:34161254
Metagenome-Assembled Genomes of Novel Taxa from an Acid Mine Drainage Environment. PMID:34161177
Bioinformatic Analysis of Circular RNA Expression. PMID:34160817
Bioinformatic Pipelines to Analyze lncRNAs RNAseq Data. PMID:34160799
Sea-Ice Bacteria Halomonas sp. Strain 363 and Paracoccus sp. Strain 392 Produce Multiple Types of Poly-3-Hydroxyalkaonoic Acid (PHA) Storage Polymers at Low Temperature. PMID:34160268
ChIP-seq protocol for sperm cells and embryos to assess environmental impacts and epigenetic inheritance. PMID:34159325
PARP-1 Regulates Estrogen-Dependent Gene Expression in Estrogen Receptor α-Positive Breast Cancer Cells. PMID:34158394
Museomics Dissects the Genetic Basis for Adaptive Seasonal Coloration in the Least Weasel. PMID:34157721
Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning. PMID:34157120
A transferrable and integrative type I-F Cascade for heterologous genome editing and transcription modulation. PMID:34157103
Molecular Evolution and Adaptation of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) Sequence Type 9. PMID:34156294
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila. PMID:34155971
New evaluation methods of read mapping by 17 aligners on simulated and empirical NGS data: an updated comparison of DNA- and RNA-Seq data from Illumina and Ion Torrent technologies. PMID:34155424
The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes. PMID:34155378
Genome-enabled discovery of evolutionary divergence in brains and behavior. PMID:34155279
Phenotypic and genomic hallmarks of a novel, potentially pathogenic rapidly growing Mycobacterium species related to the Mycobacterium fortuitum complex. PMID:34155223
Transcriptomic analysis of primate placentas and novel rhesus trophoblast cell lines informs investigations of human placentation. PMID:34154587
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans. PMID:34154419
Identification of Oxygen-Independent Pathways for Pyridine Nucleotide and Coenzyme A Synthesis in Anaerobic Fungi by Expression of Candidate Genes in Yeast. PMID:34154398
The leucine-NH4+ uptake regulator Any1 limits growth as part of a general amino acid control response to loss of La protein by fission yeast. PMID:34153074
High-resolution genetic mapping reveals cis-regulatory and copy number variation in loci associated with cytochrome P450-mediated detoxification in a generalist arthropod pest. PMID:34153029
Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus. PMID:34152810
Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons. PMID:34151776
No evidence for genetic sex determination in Daphnia magna. PMID:34150315
The elusive parasite: comparing macroscopic, immunological, and genomic approaches to identifying malaria in human skeletal remains from Sayala, Egypt (third to sixth centuries AD). PMID:34149953
Development of GBTS and KASP Panels for Genetic Diversity, Population Structure, and Fingerprinting of a Large Collection of Broccoli (Brassica oleracea L. var. italica) in China. PMID:34149754
Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses. PMID:34147139
Evaluation of whole-genome DNA methylation sequencing library preparation protocols. PMID:34147133
Chromosome Fusion Affects Genetic Diversity and Evolutionary Turnover of Functional Loci but Consistently Depends on Chromosome Size. PMID:34146107
Schistosome W-Linked Genes Inform Temporal Dynamics of Sex Chromosome Evolution and Suggest Candidate for Sex Determination. PMID:34146097
Draft de novo Genome Assembly of the Elusive Jaguarundi, Puma yagouaroundi. PMID:34146095
The genomics of mimicry: Gene expression throughout development provides insights into convergent and divergent phenotypes in a Müllerian mimicry system. PMID:34145931
Comparison of microsatellite instability detection by immunohistochemistry and molecular techniques in colorectal and endometrial cancer. PMID:34145315
Arginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells. PMID:34145242
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. PMID:34145241
A chromosome-level genome assembly of rugged rose (Rosa rugosa) provides insights into its evolution, ecology, and floral characteristics. PMID:34145222
Profiling chromatin accessibility responses in human neutrophils with sensitive pathogen detection. PMID:34145026
HCV poly U/UC sequence-induced inflammation leads to metabolic disorders in vulvar lichen sclerosis. PMID:34145025
Forward genetics in Wolbachia: Regulation of Wolbachia proliferation by the amplification and deletion of an addictive genomic island. PMID:34143770
Regional sequencing collaboration reveals persistence of the T12 Vibrio cholerae O1 lineage in West Africa. PMID:34143732
Improved molecular characterization of the Klebsiella oxytoca complex reveals the prevalence of the kleboxymycin biosynthetic gene cluster. PMID:34142942
Genetic Mutations Associated with Hormone-Positive Breast Cancer in a Small Cohort of Ethiopian Women. PMID:34142276
Genome Scan for Variable Genes Involved in Environmental Adaptations of Nubian Ibex. PMID:34142199
Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma. PMID:34142101
Primary cilia are required for the persistence of memory and stabilization of perineuronal nets. PMID:34142063
Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish. PMID:34142062
Ancient mitochondrial genomes from the Argentinian Pampas inform the early peopling of the Southern Cone of South America. PMID:34142055
Transition From PCR-Ribotyping to Whole Genome Sequencing Based Typing of Clostridioides difficile. PMID:34141631
A High-Density SNP Genetic Map Construction Using ddRAD-Seq and Mapping of Capsule Shattering Trait in Sesame. PMID:34140967
Sorghum Pan-Genome Explores the Functional Utility for Genomic-Assisted Breeding to Accelerate the Genetic Gain. PMID:34140962
The RNA Atlas expands the catalog of human non-coding RNAs. PMID:34140680
Genome sequencing and de novo assembly of the giant unicellular alga Acetabularia acetabulum using droplet MDA. PMID:34140556
3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia. PMID:34140506
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA. PMID:34140313
Functional coordination of BET family proteins underlies altered transcription associated with memory impairment in fragile X syndrome. PMID:34138732
Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance. PMID:34137790
Chromosome-Scale Assembly of the Complete Genome Sequence of Leishmania (Mundinia) martiniquensis, Isolate LSCM1, Strain LV760. PMID:34137631
Genetic evaluation of cardiomyopathies in Qatar identifies enrichment of pathogenic sarcomere gene variants and possible founder disease mutations in the Arabs. PMID:34137518
Whole-Exome Sequencing Analysis of Oral Squamous Cell Carcinoma Delineated by Tobacco Usage Habits. PMID:34136393
GRK6 Depletion Induces HIF Activity in Lung Adenocarcinoma. PMID:34136390
Experimental evolution supports signatures of sexual selection in genomic divergence. PMID:34136270
Host-Parasite Interaction of Atlantic salmon (Salmo salar) and the Ectoparasite Neoparamoeba perurans in Amoebic Gill Disease. PMID:34135900
Gut Microbial SNPs Induced by High-Fiber Diet Dominate Nutrition Metabolism and Environmental Adaption of Faecalibacterium prausnitzii in Obese Children. PMID:34135881
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells. PMID:34135508
A cohort autopsy study defines COVID-19 systemic pathogenesis. PMID:34135479
Recovery and analysis of ancient beetle DNA from subfossil packrat middens using high-throughput sequencing. PMID:34135378
Rapid identification of mutations caused by fast neutron bombardment in Medicago truncatula. PMID:34134730
Correct dosage of X chromosome transcription is controlled by a nuclear pore component. PMID:34133927
GLIS1, a potential candidate gene affect fat deposition in sheep tail. PMID:34132943
Conservation of a DNA Replication Motif among Phylogenetically Distant Budding Yeast Species. PMID:34132803
Legionella pneumophila CRISPR-Cas Suggests Recurrent Encounters with One or More Phages in the Family Microviridae. PMID:34132590
Genomic basis for drought resistance in European beech forests threatened by climate change. PMID:34132196
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas. PMID:34131149
Acute depletion of METTL3 implicates N 6-methyladenosine in alternative intron/exon inclusion in the nascent transcriptome. PMID:34131006
Large-scale genomic analysis reveals the genetic cost of chicken domestication. PMID:34130700
Identifying Genomic Regions Targeted During Eggplant Domestication Using Transcriptome Data. PMID:34130314
A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression. PMID:34129840
Inferring Population Histories for Ancient Genomes Using Genome-Wide Genealogies. PMID:34129037
BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease. PMID:34128475
Establishment of H3K9me3-dependent heterochromatin during embryogenesis in Drosophila miranda. PMID:34128466
Identification of blossom-end rot loci using joint QTL-seq and linkage-based QTL mapping in tomato. PMID:34128088
Dissecting the multi-omics atlas of the exosomes released by human lung adenocarcinoma stem-like cells. PMID:34127680
Three transmission events of Vibrio cholerae O1 into Lusaka, Zambia. PMID:34126945
Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify between-group differences in DNA methylation. PMID:34126923
Whole-exome sequencing reveals insights into genetic susceptibility to Congenital Zika Syndrome. PMID:34125832
Genomic evolution and virulence association of Clostridioides difficile sequence type 37 (ribotype 017) in China. PMID:34125660
Identification of Novel Mutations Contributing to Azole Tolerance of Aspergillus fumigatus through In Vitro Exposure to Tebuconazole. PMID:34125587
Diversity and metagenome analysis of a hydrocarbon-degrading bacterial consortium from asphalt lakes located in Wietze, Germany. PMID:34125309
North Carolina Macular Dystrophy: Phenotypic Variability and Computational Analysis of Disease-Associated Noncoding Variants. PMID:34125159
The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway. PMID:34124936
A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome. PMID:34124757
In situ microcosms deployed at the coast of British Columbia (Canada) to study dilbit weathering and associated microbial communities under marine conditions. PMID:34124756
Identification of R-loop-forming Sequences in Drosophila melanogaster Embryos and Tissue Culture Cells Using DRIP-seq. PMID:34124311
Testing the genomic stability of the Brazilian yellow fever vaccine strain using next-generation sequencing data. PMID:34123353
PSDX: A Comprehensive Multi-Omics Association Database of Populus trichocarpa With a Focus on the Secondary Growth in Response to Stresses. PMID:34122478
Comprehensive Comparison of RNA-Seq Data of SARS-CoV-2, SARS-CoV and MERS-CoV Infections: Alternative Entry Routes and Innate Immune Responses. PMID:34122413
Respiratory Co-Infections: Modulators of SARS-CoV-2 Patients' Clinical Sub-Phenotype. PMID:34122366
Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer. PMID:34121659
Population dynamics in the Japanese Archipelago since the Pleistocene revealed by the complete mitochondrial genome sequences. PMID:34121089
Leveraging breeding programs and genomic data in Norway spruce (Picea abies L. Karst) for GWAS analysis. PMID:34120648
Functional examination of lncRNAs in allotetraploid Gossypium hirsutum. PMID:34120591
Metabolic alterations mediated by STAT3 promotes drug persistence in CML. PMID:34120146
An integrated gene catalog and over 10,000 metagenome-assembled genomes from the gastrointestinal microbiome of ruminants. PMID:34118976
Low MSP-1 haplotype diversity in the West Palearctic population of the avian malaria parasite Plasmodium relictum. PMID:34118950
Development and application of the Faba_bean_130K targeted next-generation sequencing SNP genotyping platform based on transcriptome sequencing. PMID:34117907
Heterogeneous Histories of Recombination Suppression on Stickleback Sex Chromosomes. PMID:34117766
Transcriptional response to prolonged perchlorate exposure in the methanogen Methanosarcina barkeri and implications for Martian habitability. PMID:34117335
Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis. PMID:34117327
Sickle-trait hemoglobin reduces adhesion to both CD36 and EPCR by Plasmodium falciparum-infected erythrocytes. PMID:34115805
Species-Wide Transposable Element Repertoires Retrace the Evolutionary History of the Saccharomyces cerevisiae Host. PMID:34115140
Genome Assembly of the Cold-Tolerant Leaf Beetle Gonioctena quinquepunctata, an Important Resource for Studying Its Evolution and Reproductive Barriers between Species. PMID:34115123
Protein-Protein Interactions Shape Genomic Autoimmunity in the Adaptively Evolving Rhino-Deadlock-Cutoff Complex. PMID:34115120
The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia. PMID:34113809
A porcine brain-wide RNA editing landscape. PMID:34112917
Transfer RNA-derived fragments in aging Caenorhabditis elegans originate from abundant homologous gene copies. PMID:34112855
Multiple paths to cold tolerance: the role of environmental cues, morphological traits and the circadian clock gene vrille. PMID:34112109
Integrated proteomic and transcriptomic profiling identifies aberrant gene and protein expression in the sarcomere, mitochondrial complex I, and the extracellular matrix in Warmblood horses with myofibrillar myopathy. PMID:34112090
Dispersal strategies shape persistence and evolution of human gut bacteria. PMID:34111423
Lack of parent-of-origin effects in Nasonia jewel wasp: A replication and extension study. PMID:34111141
Resequencing of 672 Native Rice Accessions to Explore Genetic Diversity and Trait Associations in Vietnam. PMID:34110541
rMAP: the Rapid Microbial Analysis Pipeline for ESKAPE bacterial group whole-genome sequence data. PMID:34110280
Integration of Immunome With Disease-Gene Network Reveals Common Cellular Mechanisms Between IMIDs and Drug Repurposing Strategies. PMID:34108969
Stable Epigenetic Programming of Effector and Central Memory CD4 T Cells Occurs Within 7 Days of Antigen Exposure In Vivo. PMID:34108962
A Multi-Omics Analysis of Mucosal-Associated-Invariant T Cells Reveals Key Drivers of Distinct Modes of Activation. PMID:34108957
SNP detection and population structure evaluation of Salix gordejevii Y. L. Chang et Skv. in Hunshandake Sandland, Inner Mongolia, China. PMID:34108824
Divergence of a genomic island leads to the evolution of melanization in a halophyte root fungus. PMID:34108667
RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability. PMID:34108665
ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation. PMID:34108663
H3K27me3 demethylases alter HSP22 and HSP17.6C expression in response to recurring heat in Arabidopsis. PMID:34108473
Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis. PMID:34108460
High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity. PMID:34107251
Genomic diversity of 39 samples of Pyropia species grown in Japan. PMID:34106965
Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus. PMID:34106569
Single-Cell Transcriptome Analysis Uncovers Intratumoral Heterogeneity and Underlying Mechanisms for Drug Resistance in Hepatobiliary Tumor Organoids. PMID:34105295
Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells. PMID:34105235
The complete chloroplast genome of Abeliophyllum distichum f. lilacinum Nakai (Oleaceae) from the Chungbuk Province, Korea. PMID:34104762
Somatic Mutation Profiling of Papillary Thyroid Carcinomas by Whole-exome Sequencing and Its Relationship with Clinical Characteristics. PMID:34104084
Transcriptomic analysis of cork during seasonal growth highlights regulatory and developmental processes from phellogen to phellem formation. PMID:34103550
Rapid and accurate alignment of nucleotide conversion sequencing reads with HISAT-3N. PMID:34103331
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia. PMID:34103329
Genomic signatures of spatially divergent selection at clownfish range margins. PMID:34102891
Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data. PMID:34100982
Characterization of the Blood and Cerebrospinal Fluid Microbiome in Children with Bacterial Meningitis and Its Potential Correlation with Inflammation. PMID:34100633
Comparative analysis of phenotypic plasticity sheds light on the evolution and molecular underpinnings of locust phase polyphenism. PMID:34099755
Identification of Nrf2-responsive microRNA networks as putative mediators of myocardial reductive stress. PMID:34099738
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. PMID:34099734
A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation. PMID:34099688
RNA structure probing reveals the structural basis of Dicer binding and cleavage. PMID:34099665
Multifaceted regulation of hepatic lipid metabolism by YY1. PMID:34099540
The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle. PMID:34099014
In-situ muconic acid extraction reveals sugar consumption bottleneck in a xylose-utilizing Saccharomyces cerevisiae strain. PMID:34098954
Construction of DNA Tools for Hyperexpression in Marchantia Chloroplasts. PMID:34097383
Detecting SARS-CoV-2 and its variant strains with a full genome tiling array. PMID:34097003
Dysregulation of Transcription Factor Networks Unveils Different Pathways in Human Papillomavirus 16-Positive Squamous Cell Carcinoma and Adenocarcinoma of the Uterine Cervix. PMID:34094909
Transcriptome-Wide Identification of G-to-A RNA Editing in Chronic Social Defeat Stress Mouse Models. PMID:34093668
Characterizing Genetic Regulatory Elements in Ovine Tissues. PMID:34093640
Comprehensive Transcriptome Analyses Reveal Candidate Genes for Variation in Seed Size/Weight During Peanut (Arachis hypogaea L.) Domestication. PMID:34093624
GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments. PMID:34093598
Complete Genome Sequence of Xylella taiwanensis and Comparative Analysis of Virulence Gene Content With Xylella fastidiosa. PMID:34093511
The effect of methanol fixation on single-cell RNA sequencing data. PMID:34090348
SnoRNA copy regulation affects family size, genomic location and family abundance levels. PMID:34090325
Transcriptome analysis of primary chicken cells infected with infectious bronchitis virus strain K047-12 isolated in Korea. PMID:34089367
Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution. PMID:34088847
A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes. PMID:34088716
Identification of 3'-UTR single nucleotide variants and prediction of select protein imbalance in mesial temporal lobe epilepsy patients. PMID:34086756
Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity. PMID:34086055
Generation of unequal nuclear genotype proportions in Rhizophagus irregularis progeny causes allelic imbalance in gene transcription. PMID:34085297
Mapping RNA Modifications Using Photo-Crosslinking-Assisted Modification Sequencing. PMID:34085242
Molecular mechanisms of fat deposition: IL-6 is a hub gene in fat lipolysis, comparing thin-tailed with fat-tailed sheep breeds. PMID:34084904
Rapid genotype imputation from sequence with reference panels. PMID:34083788
Wolfberry genomes and the evolution of Lycium (Solanaceae). PMID:34083720
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer. PMID:34083537
A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases. PMID:34083435
A role for condensin in mediating transcriptional adaptation to environmental stimuli. PMID:34083394
Historical genomics reveals the evolutionary mechanisms behind multiple outbreaks of the host-specific coffee wilt pathogen Fusarium xylarioides. PMID:34082717
Genome-Inferred Correspondence between Phylogeny and Metabolic Traits in the Wild Drosophila Gut Microbiome. PMID:34081101
Characterising Foot-and-Mouth Disease Virus in Clinical Samples Using Nanopore Sequencing. PMID:34079833
Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment. PMID:34079046
Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. PMID:34078898
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. PMID:34078885
Gene count from target sequence capture places three whole genome duplication events in Hibiscus L. (Malvaceae). PMID:34078291
Whole-genome sequencing identifies functional noncoding variation in SEMA3C that cosegregates with dyslexia in a multigenerational family. PMID:34076780
The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma. PMID:34076685
Investigation of genetic markers for intramuscular fat in the hybrid Wagyu cattle with bulked segregant analysis. PMID:34075159
Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19. PMID:34075090
Genome Editing to Generate Sake Yeast Strains with Eight Mutations That Confer Excellent Brewing Characteristics. PMID:34073778
AID Contributes to Accelerated Disease Progression in the TCL1 Mouse Transplant Model for CLL. PMID:34073525
In Vitro Selection of High-Level Beta-Lactam Resistance in Methicillin-Susceptible Staphylococcus aureus. PMID:34073276
Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer. PMID:34072580
Transcriptome Profiling of Embryonic Retinal Pigment Epithelium Reprogramming. PMID:34072522
Nanopore Sequencing Unveils Diverse Transcript Variants of the Epithelial Cell-Specific Transcription Factor Elf-3 in Human Malignancies. PMID:34072506
Polymorphism in the Chloroplast ATP Synthase Beta-Subunit Is Associated with a Maternally Inherited Enhanced Cold Recovery in Cucumber. PMID:34072439
Characteristics of the Soil Microbial Communities in Different Slope Positions along an Inverted Stone Slope in a Degraded Karst Tiankeng. PMID:34072056
The Genes of Freedom: Genome-Wide Insights into Marronage, Admixture and Ethnogenesis in the Gulf of Guinea. PMID:34071462
Global Chromatin Changes Resulting from Single-Gene Inactivation-The Role of SMARCB1 in Malignant Rhabdoid Tumor. PMID:34071089
Rare Germline Variants in Chordoma-Related Genes and Chordoma Susceptibility. PMID:34070849
Calreticulin Deficiency Disturbs Ribosome Biogenesis and Results in Retardation in Embryonic Kidney Development. PMID:34070742
Comparative Analysis of the Intermolt and Postmolt Hepatopancreas Transcriptomes Provides Insight into the Mechanisms of Procambarus clarkii Molting Process. PMID:34070595
Epigenetic Modulating Chemicals Significantly Affect the Virulence and Genetic Characteristics of the Bacterial Plant Pathogen Xanthomonas campestris pv. campestris. PMID:34070403
The Detection and Bioinformatic Analysis of Alternative 3' UTR Isoforms as Potential Cancer Biomarkers. PMID:34070203
Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response. PMID:34070078
INTACT vs. FANS for Cell-Type-Specific Nuclei Sorting: A Comprehensive Qualitative and Quantitative Comparison. PMID:34069481
TILLING-by-Sequencing+ Reveals the Role of Novel Fatty Acid Desaturases (GmFAD2-2s) in Increasing Soybean Seed Oleic Acid Content. PMID:34069320
Differential Expression of Amanitin Biosynthetic Genes and Novel Cyclic Peptides in Amanita molliuscula. PMID:34069263
Pilot Screening of Cell-Free mtDNA in NIPT: Quality Control, Variant Calling, and Haplogroup Determination. PMID:34069212
Microbial Composition of SCOBY Starter Cultures Used by Commercial Kombucha Brewers in North America. PMID:34068887
Mapping of Quantitative Trait Loci Controlling Egg-Quality and -Production Traits in Japanese Quail (Coturnix japonica) Using Restriction-Site Associated DNA Sequencing. PMID:34068239
Patterns in Genotype Composition of Indian Isolates of the Bombyx mori Nucleopolyhedrovirus and Bombyx mori Bidensovirus. PMID:34068017
Identification of an Attenuated Substrain of Francisella tularensis SCHU S4 by Phenotypic and Genotypic Analyses. PMID:34067337
Oryzias curvinotus in Sanya Does Not Contain the Male Sex-Determining Gene dmy. PMID:34066583
Cell-Free DNA Analysis by Whole-Exome Sequencing for Hepatocellular Carcinoma: A Pilot Study in Thailand. PMID:34066484
Use of High-Throughput Sequencing and Two RNA Input Methods to Identify Viruses Infecting Tomato Crops. PMID:34066188
Antibiotic-Resistant Enterobacteriaceae in Wastewater of Abattoirs. PMID:34065908
Mycobacterium tuberculosis Binds Human Serum Amyloid A, and the Interaction Modulates the Colonization of Human Macrophages and the Transcriptional Response of the Pathogen. PMID:34065319
Dissecting the RecA-(In)dependent Response to Mitomycin C in Mycobacterium tuberculosis Using Transcriptional Profiling and Proteomics Analyses. PMID:34064944
The AraC-Type Transcriptional Regulator GliR (PA3027) Activates Genes of Glycerolipid Metabolism in Pseudomonas aeruginosa. PMID:34064685
Metaviromes Reveal the Dynamics of Pseudomonas Host-Specific Phages Cultured and Uncultured by Plaque Assay. PMID:34064231
Identification of a Stable, Non-Canonically Regulated Nrf2 Form in Lung Cancer Cells. PMID:34063559
Dual RNA-Sequencing Analysis of Resistant (Pinus pinea) and Susceptible (Pinus radiata) Hosts during Fusarium circinatum Challenge. PMID:34063405
Expanded transcriptomic view of strawberry fruit ripening through meta-analysis. PMID:34061906
Identification of in vivo Hox13-binding sites reveals an essential locus controlling zebrafish brachyury expression. PMID:34061173
A biological and genomic comparison of a drug-resistant and a drug-susceptible strain of Candida auris isolated from Beijing, China. PMID:34060424
Genome Scale Analysis Reveals IscR Directly and Indirectly Regulates Virulence Factor Genes in Pathogenic Yersinia. PMID:34060331
Heat stress and immune response phenotype affect DNA methylation in blood mononuclear cells from Holstein dairy cows. PMID:34059695
Tissue and regional expression patterns of dicistronic tRNA-mRNA transcripts in grapevine (Vitis vinifera) and their evolutionary co-appearance with vasculature in land plants. PMID:34059643
Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa. PMID:34059118
Whole-genome resequencing provides insights into the population structure and domestication signatures of ducks in eastern China. PMID:34058976
Characterizing the oligogenic architecture of plant growth phenotypes informs genomic selection approaches in a common wheat population. PMID:34058974
A new approach to decode DNA methylome and genomic variants simultaneously from double strand bisulfite sequencing. PMID:34058751
Anaerobic Sulfur Oxidation Underlies Adaptation of a Chemosynthetic Symbiont to Oxic-Anoxic Interfaces. PMID:34058098
DNA Topoisomerase 3α Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi. PMID:34055812
Association of CASR, CALCR, and ORAI1 Genes Polymorphisms With the Calcium Urolithiasis Development in Russian Population. PMID:34054913
Extended Archaeal Histone-Based Chromatin Structure Regulates Global Gene Expression in Thermococcus kodakarensis. PMID:34054788
Circulation of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli of Pandemic Sequence Types 131, 648, and 410 Among Hospitalized Patients, Caregivers, and the Community in Rwanda. PMID:34054764
Whole-Genome sequencing and comparative genomics of Mycobacterium spp. from farmed Atlantic and coho salmon in Chile. PMID:34052985
Overexpression of a single ORF can extend chronological lifespan in yeast if retrograde signaling and stress response are stimulated. PMID:34052951
Dysregulation of COVID-19 related gene expression in the COPD lung. PMID:34051791
Detection of copy number variants in African goats using whole genome sequence data. PMID:34051743
Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors. PMID:34051140
The Assembled and Annotated Genome of the Fairy-Ring Fungus Marasmius oreades. PMID:34051082
A single m6A modification in U6 snRNA diversifies exon sequence at the 5' splice site. PMID:34050143
Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos. PMID:34050011
Multiplexed single-cell profiling of chromatin states at genomic loci by expansion microscopy. PMID:34048564
Characterization of a Sex-Determining Region and Its Genomic Context via Statistical Estimates of Haplotype Frequencies in Daughters and Sons Sequenced in Pools. PMID:34048551
PTEN somatic mutations contribute to spectrum of cerebral overgrowth. PMID:34048549
Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2. PMID:34047695
Genomic Heterogeneity and Clonal Evolution in Gastroesophageal Junction Cancer Revealed by Single Cell DNA Sequencing. PMID:34046362
Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer. PMID:34045764
Retinoic acid signaling is critical during the totipotency window in early mammalian development. PMID:34045724
Genome structural evolution in Brassica crops. PMID:34045706
Conserved noncoding sequences provide insights into regulatory sequence and loss of gene expression in maize. PMID:34045362
Genetic alteration of Chinese patients with rectal mucosal melanoma. PMID:34044811
The Genomic Signature of Allopatric Speciation in a Songbird Is Shaped by Genome Architecture (Aves: Certhia americana). PMID:34042960
Metagenomes, Metatranscriptomes, and Metagenome-Assembled Genomes from Chesapeake and Delaware Bay (USA) Water Samples. PMID:34042480
Genome Sequencing Identified a SARS-CoV-2 Lineage B.1.1.7 Strain with a High Number of Mutations from Dhaka, Bangladesh. PMID:34042471
Natural variants suppress mutations in hundreds of essential genes. PMID:34042294
Improved plant cytosine base editors with high editing activity, purity, and specificity. PMID:34042262
RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry. PMID:34042048
A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets. PMID:34041503
Differential disease severity and whole-genome sequence analysis for human influenza A/H1N1pdm virus in 2015-2016 influenza season. PMID:34040796
A Benchmark of Genetic Variant Calling Pipelines Using Metagenomic Short-Read Sequencing. PMID:34040632
Easymap: A User-Friendly Software Package for Rapid Mapping-by-Sequencing of Point Mutations and Large Insertions. PMID:34040621
A phase-separated nuclear GBPL circuit controls immunity in plants. PMID:34040255
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia. PMID:34040147
Extracellular DNA of slow growers of mycobacteria and its contribution to biofilm formation and drug tolerance. PMID:34040029
Fast genetic mapping using insertion-deletion polymorphisms in Caenorhabditis elegans. PMID:34040027
Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family. PMID:34040021
Aquaculture mediates global transmission of a viral pathogen to wild salmon. PMID:34039598
Population transcriptomic sequencing reveals allopatric divergence and local adaptation in Pseudotaxus chienii (Taxaceae). PMID:34039278
Genetic interaction network has a very limited impact on the evolutionary trajectories in continuous culture-grown populations of yeast. PMID:34039270
Evaluating the accuracy of Listeria monocytogenes assemblies from quasimetagenomic samples using long and short reads. PMID:34039264
Genetic effects on liver chromatin accessibility identify disease regulatory variants. PMID:34038741
HuConTest: Testing Human Contamination in Great Ape Samples. PMID:34038549
Genome-wide comparative analyses of GATA transcription factors among 19 Arabidopsis ecotype genomes: Intraspecific characteristics of GATA transcription factors. PMID:34038437
PlantDeepSEA, a deep learning-based web service to predict the regulatory effects of genomic variants in plants. PMID:34037796
Broad Concordance in the Spatial Distribution of Adaptive and Neutral Genetic Variation across an Elevational Gradient in Deer Mice. PMID:34037784
Hardware Acceleration of Genomics Data Analysis: Challenges and Opportunities. PMID:34037688
Heterozygous GJA1 variants with ocular phenotype: Missense in domain but truncation out of domain. PMID:34035645
Characterization of gross genome rearrangements in Deinococcus radiodurans recA mutants. PMID:34035321
A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion. PMID:34035279
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase. PMID:34035251
Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses. PMID:34034819
GRiNCH: simultaneous smoothing and detection of topological units of genome organization from sparse chromatin contact count matrices with matrix factorization. PMID:34034791
Samplot: a platform for structural variant visual validation and automated filtering. PMID:34034781
Chromosome-level genome assembly and manually-curated proteome of model necrotroph Parastagonospora nodorum Sn15 reveals a genome-wide trove of candidate effector homologs, and redundancy of virulence-related functions within an accessory chromosome. PMID:34034667
The divergence of alternative splicing between ohnologs in teleost fishes. PMID:34034651
Experimental evolution can enhance benefits of rhizobia to novel legume hosts. PMID:34034525
The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency. PMID:34033652
Unsupervised tensor decomposition-based method to extract candidate transcription factors as histone modification bookmarks in post-mitotic transcriptional reactivation. PMID:34032804
Prisons as ecological drivers of fitness-compensated multidrug-resistant Mycobacterium tuberculosis. PMID:34031604
The transcriptional landscape of a rewritten bacterial genome reveals control elements and genome design principles. PMID:34031412
MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells. PMID:34031396
Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication. PMID:34031383
Immunotranscriptomic profiling the acute and clearance phases of a human challenge dengue virus serotype 2 infection model. PMID:34031380
Re-examination of two diatom reference genomes using long-read sequencing. PMID:34030633
Transcriptomic and metabolomic characterization of post-hatch metabolic reprogramming during hepatic development in the chicken. PMID:34030631
A new mouse SNP genotyping assay for speed congenics: combining flexibility, affordability, and power. PMID:34030629
Quasispecies of SARS-CoV-2 revealed by single nucleotide polymorphisms (SNPs) analysis. PMID:34030593
Genomic epidemiology of Candida auris in a general hospital in Shenyang, China: a three-year surveillance study. PMID:34027824
Generation of gene-level resolution chromosome contact maps in bacteria and archaea. PMID:34027477
The Xa7 resistance gene guards the rice susceptibility gene SWEET14 against exploitation by the bacterial blight pathogen. PMID:34027391
Parallel and Intertwining Threads of Domestication in Allopolyploid Cotton. PMID:34026441
Adaptive markers distinguish North and South Pacific Albacore amid low population differentiation. PMID:34025772
Standing genetic variation in laboratory populations of insecticide-susceptible Phlebotomus papatasi and Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae) for the evolution of resistance. PMID:34025765
Transcriptome Analysis of Tetraploid and Octoploid Common Reed (Phragmites australis). PMID:34025698
Fine Mapping and Candidate Gene Identification of a White Flower Gene BrWF3 in Chinese Cabbage (Brassica rapa L. ssp. pekinensis). PMID:34025693
HLA class I genes modulate disease risk and age at onset together with DR-DQ in Chinese patients with insulin-requiring type 1 diabetes. PMID:34023962
In vivo tissue-specific chromatin profiling in Drosophila melanogaster using GFP-tagged nuclei. PMID:34022041
The Worldwide Invasion of Drosophila suzukii Is Accompanied by a Large Increase of Transposable Element Load and a Small Number of Putatively Adaptive Insertions. PMID:34021759
Global in situ profiling of RNA-RNA spatial interactions with RIC-seq. PMID:34021296
Deep ocean metagenomes provide insight into the metabolic architecture of bathypelagic microbial communities. PMID:34021239
IsoSplitter: identification and characterization of alternative splicing sites without a reference genome. PMID:34021065
Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank. PMID:34020714
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. PMID:34019811
Combining comparative genomic analysis with machine learning reveals some promising diagnostic markers to identify five common pathogenic non-tuberculous mycobacteria. PMID:34019733
Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF. PMID:34019588
A High-Throughput Chromatin Immunoprecipitation Sequencing Approach to Study the Role of MYC on the Epigenetic Landscape. PMID:34019291
Analysis of Myc Chromatin Binding by Calibrated ChIP-Seq Approach. PMID:34019290
MesKit: a tool kit for dissecting cancer evolution of multi-region tumor biopsies through somatic alterations. PMID:34018555
Quantifying splice-site usage: a simple yet powerful approach to analyze splicing. PMID:34017946
Recombination and biased segregation of mitochondrial genomes during crossing and meiosis of different Schizosaccharomyces pombe strains. PMID:34017941
Mutation and Copy Number Alterations Analysis of KIF23 in Glioma. PMID:34017355
Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation. PMID:34017130
Complete Genome Sequence of Lentilactobacillus parabuchneri Strain KEM. PMID:34016686
Chromosome-Level Genome Sequence of Leishmania (Leishmania) tropica Strain CDC216-162, Isolated from an Afghanistan Clinical Case. PMID:34016685
Genomic and temporal analyses of Mycobacterium bovis in southern Brazil. PMID:34016251
A microProtein repressor complex in the shoot meristem controls the transition to flowering. PMID:34015131
NGSremix: a software tool for estimating pairwise relatedness between admixed individuals from next-generation sequencing data. PMID:34015083
ChromInst: A single cell sequencing technique to accomplish pre-implantation comprehensive chromosomal screening overnight. PMID:34015059
Whole-genome sequencing and phylogenetic analysis of rabies viruses from Jordan. PMID:34014930
VCF2CAPS-A high-throughput CAPS marker design from VCF files and its test-use on a genotyping-by-sequencing (GBS) dataset. PMID:34014924
AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice. PMID:34013328
Identification of genetic variations associated with drug resistance in non-small cell lung cancer patients undergoing systemic treatment. PMID:34013324
Comprehensive transcriptome analysis of colorectal cancer risk of hyperglycemia in humans. PMID:34012653
Genome Sequencing and Assembly Strategies and a Comparative Analysis of the Genomic Characteristics in Penaeid Shrimp Species. PMID:34012463
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics. PMID:34012112
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates. PMID:34012082
Quantitative trait locus analysis of parasitoid counteradaptation to symbiont-conferred resistance. PMID:34012059
Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. PMID:34012049
Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity. PMID:34011996
Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer. PMID:34011560
Lessons learned from the investigation of a COVID-19 cluster in Creil, France: effectiveness of targeting symptomatic cases and conducting contact tracing around them. PMID:34011278
Investigating the impact of reference assembly choice on genomic analyses in a cattle breed. PMID:34011274
Integration of 1:1 orthology maps and updated datasets into Echinobase. PMID:34010390
Detection of von Hippel-Lindau gene mutation in circulating cell-free DNA for clear cell renal cell carcinoma. PMID:34009695
Ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains in hexaploid wheat in a dosage-dependent manner. PMID:34009390
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion. PMID:34009296
Construction of a high density genetic map for hexaploid kiwifruit (Actinidia chinensis var. deliciosa) using genotyping by sequencing. PMID:34009255
A novel temperate phage, vB_PstS-pAN, induced from the naphthalene-degrading bacterium Pseudomonas stutzeri AN10. PMID:34008105
Ceftazidime-Avibactam Resistance in Klebsiella pneumoniae Sequence Type 11 Due to a Mutation in Plasmid-Borne bla kpc-2 to bla kpc-33, in Henan, China. PMID:34007191
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis. PMID:34006870
Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin. PMID:34006846
Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila. PMID:34006653
CTCF looping is established during gastrulation in medaka embryos. PMID:34006570
Chromatin architecture transitions from zebrafish sperm through early embryogenesis. PMID:34006569
Infection, dissemination, and transmission efficiencies of Zika virus in Aedes aegypti after serial passage in mosquito or mammalian cell lines or alternating passage in both cell types. PMID:34006306
Gene expression and alternative splicing dynamics are perturbed in female head transcriptomes following heterospecific copulation. PMID:34006224
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer. PMID:34004147
Restricted dispersal in a sea of gene flow. PMID:34004134
Nitric oxide coordinates growth, development, and stress response via histone modification and gene expression. PMID:34003928
Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts. PMID:34003848
Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts. PMID:34003819
Integrated sensing of host stresses by inhibition of a cytoplasmic two-component system controls M. tuberculosis acute lung infection. PMID:34003742
A 24,482-bp deletion is associated with increased seed weight in Brassica napus L. PMID:34002254
Analysis of Genomic DNA from Medieval Plague Victims Suggests Long-Term Effect of Yersinia pestis on Human Immunity Genes. PMID:34002224
Repetitive genomic regions and the inference of demographic history. PMID:34002046
Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis. PMID:34002013
Dual RNA-seq analysis of in vitro infection multiplicity and RNA depletion methods in Chlamydia-infected epithelial cells. PMID:34001998
Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease. PMID:34001905
Transcription of Cystathionine β-Lyase (MetC) Is Repressed by HeuR in Campylobacter jejuni, and Methionine Biosynthesis Facilitates Colonocyte Invasion. PMID:34001558
A Novel Series of Indole Alkaloid Derivatives Inhibit Dengue and Zika Virus Infection by Interference with the Viral Replication Complex. PMID:34001508
Genomic reconstruction of fossil and living microorganisms in ancient Siberian permafrost. PMID:34001281
Genome-wide detection of CNVs and their association with performance traits in broilers. PMID:34001004
ddRAD sequencing: an emerging technology added to the biosecurity toolbox for tracing the origin of brown marmorated stink bug, Halyomorpha halys (Hemiptera: Pentatomidae). PMID:34000993
Evaluation of tools for identifying large copy number variations from ultra-low-coverage whole-genome sequencing data. PMID:34000988
Regional Spread of blaNDM-1-Containing Klebsiella pneumoniae ST147 in Post-Acute Care Facilities. PMID:33999991
Structure-activity mapping of ARHGAP36 reveals regulatory roles for its GAP homology and C-terminal domains. PMID:33999959
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus. PMID:33999949
Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism. PMID:33999436
Plasmids shape the diverse accessory resistomes of Escherichia coli ST131. PMID:33997610
The Comparative Analyses of Six Complete Chloroplast Genomes of Morphologically Diverse Chenopodium album L. (Amaranthaceae) Collected in Korea. PMID:33996994
Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture. PMID:33996806
Tlx3 Exerts Direct Control in Specifying Excitatory Over Inhibitory Neurons in the Dorsal Spinal Cord. PMID:33996801
LoReTTA, a user-friendly tool for assembling viral genomes from PacBio sequence data. PMID:33996146
Application of Hi-C and other omics data analysis in human cancer and cell differentiation research. PMID:33995903
Precise Species Detection in Traditional Herbal Patent Medicine, Qingguo Wan, Using Shotgun Metabarcoding. PMID:33995010
Comparative phylogenetics of repetitive elements in a diverse order of flowering plants (Brassicales). PMID:33993297
Transcriptional reprogramming by oxidative stress occurs within a predefined chromatin accessibility landscape. PMID:33992677
PEPPRO: quality control and processing of nascent RNA profiling data. PMID:33992117
Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs. PMID:33991511
High-throughput full-length single-cell RNA-seq automation. PMID:33990801
Genome-resolved metagenomics suggests a mutualistic relationship between Mycoplasma and salmonid hosts. PMID:33990699
Oxygen tension modulates the mitochondrial genetic bottleneck and influences the segregation of a heteroplasmic mtDNA variant in vitro. PMID:33990696
A live imaging system to analyze spatiotemporal dynamics of RNA polymerase II modification in Arabidopsis thaliana. PMID:33990678
Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. PMID:33990599
Oxygen suppression of macroscopic multicellularity. PMID:33990594
bric à brac controls sex pheromone choice by male European corn borer moths. PMID:33990556
Cardiac cell type-specific gene regulatory programs and disease risk association. PMID:33990324
Parallel and population-specific gene regulatory evolution in cold-adapted fly populations. PMID:33989401
The Presence of Ancient Core Genes Reveals Endogenization from Diverse Viral Ancestors in Parasitoid Wasps. PMID:33988720
Accelerated Evolution of Tissue-Specific Genes Mediates Divergence Amidst Gene Flow in European Green Lizards. PMID:33988711
HyRAD-X Exome Capture Museomics Unravels Giant Ground Beetle Evolution. PMID:33988685
A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing. PMID:33988501
Hapo-G, haplotype-aware polishing of genome assemblies with accurate reads. PMID:33987534
The regulatory genome of the malaria vector Anopheles gambiae: integrating chromatin accessibility and gene expression. PMID:33987532
Systematic in silico Evaluation of Leishmania spp. Proteomes for Drug Discovery. PMID:33987166
Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression. PMID:33986751
Quantitative profiling of pseudouridylation dynamics in native RNAs with nanopore sequencing. PMID:33986546
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands. PMID:33986537
Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases. PMID:33986449
Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes. PMID:33983929
Comparative Analyses of Gibbon Centromeres Reveal Dynamic Genus-Specific Shifts in Repeat Composition. PMID:33983366
A multi-gene knockdown approach reveals a new role for Pax6 in controlling organ number in Drosophila. PMID:33982759
DELLA proteins BnaA6.RGA and BnaC7.RGA negatively regulate fatty acid biosynthesis by interacting with BnaLEC1s in Brassica napus. PMID:33982357
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System. PMID:33982246
MINTyper: an outbreak-detection method for accurate and rapid SNP typing of clonal clusters with noisy long reads. PMID:33981853
Reconstruction of ancient microbial genomes from the human gut. PMID:33981035
Novel taxa of Acidobacteriota implicated in seafloor sulfur cycling. PMID:33981000
A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells. PMID:33980982
Genes and pathways monotonically dysregulated during progression from normal through leukoplakia to gingivo-buccal oral cancer. PMID:33980865
Microbiome Analysis Reveals Diversity and Function of Mollicutes Associated with the Eastern Oyster, Crassostrea virginica. PMID:33980678
The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. PMID:33980486
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation. PMID:33979616
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages. PMID:33979301
Enriched Opportunistic Pathogens Revealed by Metagenomic Sequencing Hint Potential Linkages between Pharyngeal Microbiota and COVID-19. PMID:33978940
A novel remitting leukodystrophy associated with a variant in FBP2. PMID:33977262
Historical effective population size of North American hoary bat (Lasiurus cinereus) and challenges to estimating trends in contemporary effective breeding population size from archived samples. PMID:33976981
Transcriptome assembly and differential gene expression of the invasive avian malaria parasite Plasmodium relictum in Hawai'i. PMID:33976860
Genome-wide simple sequence repeats (SSR) markers discovered from whole-genome sequence comparisons of multiple spinach accessions. PMID:33976335
Haplotype-resolved genome assembly enables gene discovery in the red palm weevil Rhynchophorus ferrugineus. PMID:33976235
Lying in wait: the resurgence of dengue virus after the Zika epidemic in Brazil. PMID:33976183
Taxonomic signatures of cause-specific mortality risk in human gut microbiome. PMID:33976176
Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei. PMID:33976138
Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections. PMID:33976135
The RNA landscape of the human placenta in health and disease. PMID:33976128
Identification of c-di-GMP/FleQ-Regulated New Target Genes, Including cyaA, Encoding Adenylate Cyclase, in Pseudomonas putida. PMID:33975969
Novel Mycoviruses Discovered in the Mycovirome of a Necrotrophic Fungus. PMID:33975945
Functional and Comparative Analysis of Centromeres Reveals Clade-Specific Genome Rearrangements in Candida auris and a Chromosome Number Change in Related Species. PMID:33975937
Transcriptomics analysis of differentially expressed genes in subcutaneous and perirenal adipose tissue of sheep as affected by their pre- and early postnatal malnutrition histories. PMID:33975549
Dynamic subcellular compartmentalization ensures fidelity of piRNA biogenesis in silkworms. PMID:33973704
Comparative Genome Analyses Highlight Transposon-Mediated Genome Expansion and the Evolutionary Architecture of 3D Genomic Folding in Cotton. PMID:33973633
Two alternative methods for the retrieval of somatic cell populations from the mouse ovary. PMID:33973015
Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge. PMID:33972939
A TILLING by sequencing approach to identify induced mutations in sunflower genes. PMID:33972605
Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week. PMID:33972544
Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations. PMID:33972509
Novel functional sequences uncovered through a bovine multiassembly graph. PMID:33972446
Identification of the conserved long non-coding RNAs in myogenesis. PMID:33971818
DR2S: an integrated algorithm providing reference-grade haplotype sequences from heterozygous samples. PMID:33971817
The diversity of opsins in Lake Baikal amphipods (Amphipoda: Gammaridae). PMID:33971810
The microbiome of deep-sea fish reveals new microbial species and a sparsity of antibiotic resistance genes. PMID:33970781
Identification of quantitative trait loci associated with calmness and gentleness in honey bees using whole-genome sequences. PMID:33970494
Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay. PMID:33970102
Molecular Epidemiology of Salmonellosis in Florida, USA, 2017-2018. PMID:33968960
Long-Read Sequencing to Unravel Complex Structural Variants of CEP78 Leading to Cone-Rod Dystrophy and Hearing Loss. PMID:33968938
The Complete Chloroplast Genome of Plukenetia volubilis Provides Insights Into the Organelle Inheritance. PMID:33968119
Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints. PMID:33968050
Virus Prevalence and Genetic Diversity Across a Wild Bumblebee Community. PMID:33967987
BiSulfite Bolt: A bisulfite sequencing analysis platform. PMID:33966074
Analysis of differentially expressed Sclerotinia sclerotiorum genes during the interaction with moderately resistant and highly susceptible chickpea lines. PMID:33964897
Chromosome-Level Assembly of the Atlantic Silverside Genome Reveals Extreme Levels of Sequence Diversity and Structural Genetic Variation. PMID:33964136
TieBrush: an efficient method for aggregating and summarizing mapped reads across large datasets. PMID:33964128
Locally Adaptive Inversions Modulate Genetic Variation at Different Geographic Scales in a Seaweed Fly. PMID:33963409
Whole genome sequencing reveals high differentiation, low levels of genetic diversity and short runs of homozygosity among Swedish wels catfish. PMID:33963302
Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals. PMID:33963185
ILRUN Downregulates ACE2 Expression and Blocks Infection of Human Cells by SARS-CoV-2. PMID:33963054
Dual RNAseq highlights the kinetics of skin microbiome and fish host responsiveness to bacterial infection. PMID:33962693
scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing. PMID:33962667
Promoter G-quadruplex folding precedes transcription and is controlled by chromatin. PMID:33962653
Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection. PMID:33961822
Genome-wide identification of loci modifying spike-branching in tetraploid wheat. PMID:33961064
NGScloud2: optimized bioinformatic analysis using Amazon Web Services. PMID:33959420
Ocean-wide genomic variation in Gray's beaked whales, Mesoplodon grayi. PMID:33959341
Evaluation of the Microba Community Profiler for Taxonomic Profiling of Metagenomic Datasets From the Human Gut Microbiome. PMID:33959106
Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling. PMID:33959012
Phylogenetic history of patrilineages rare in northern and eastern Europe from large-scale re-sequencing of human Y-chromosomes. PMID:33958743
Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC1. PMID:33958653
Clear phylogeographic pattern and genetic structure of wild boar Sus scrofa population in Central and Eastern Europe. PMID:33958636
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues. PMID:33958444
Complete Genome Sequence of a Pseudomonas simiae Strain with Biocontrol Potential against Aphanomyces Root Rot. PMID:33958418
Metagenome-Assembled Genomes of 12 Bacterial Species from Biofouled Plastic Fabrics Harbor Multiple Genes for Degradation of Hydrocarbons. PMID:33958410
Complete Genome Sequence of the Endosymbiotic Bacterium "Candidatus Riesia pediculicola". PMID:33958407
Limited haplotype diversity underlies polygenic trait architecture across 70 years of wheat breeding. PMID:33957956
Embryo CHH hypermethylation is mediated by RdDM and is autonomously directed in Brassica rapa. PMID:33957938
The genome of a wild Medicago species provides insights into the tolerant mechanisms of legume forage to environmental stress. PMID:33957908
Identification of a genetic variant underlying familial cases of recurrent benign paroxysmal positional vertigo. PMID:33956893
A natural knockout of the MYO7A gene leads to pre-weaning mortality in pigs. PMID:33955556
Photoperiod-responsive changes in chromatin accessibility in phloem companion and epidermis cells of Arabidopsis leaves. PMID:33955490
Ecologically coherent population structure of uncultivated bacterioplankton. PMID:33953362
High biodiversity in a benzene-degrading nitrate-reducing culture is sustained by a few primary consumers. PMID:33953314
Concurrent X chromosome inactivation and upregulation during non-human primate preimplantation development revealed by single-cell RNA-sequencing. PMID:33953270
Multiple roles of H2A.Z in regulating promoter chromatin architecture in human cells. PMID:33953180
RNA Viral Metagenome Analysis of Subnanogram dsRNA Using Fragmented and Primer Ligated dsRNA Sequencing (FLDS). PMID:33952860
Genomic Elucidation of a COVID-19 Resurgence and Local Transmission of SARS-CoV-2 in Guangzhou, China. PMID:33952598
Intergenic RNA mainly derives from nascent transcripts of known genes. PMID:33952325
Transcriptional profile of oil palm pathogen, Ganoderma boninense, reveals activation of lignin degradation machinery and possible evasion of host immune response. PMID:33952202
Forensic nanopore sequencing of STRs and SNPs using Verogen's ForenSeq DNA Signature Prep Kit and MinION. PMID:33950286
Evolutionary Dynamics of the OR Gene Repertoire in Teleost Fishes: Evidence of an Association with Changes in Olfactory Epithelium Shape. PMID:33950257
De Novo Mutation Rate Variation and Its Determinants in Chlamydomonas. PMID:33950243
The Pop-Gen Pipeline Platform: A Software Platform for Population Genomic Analyses. PMID:33950197
The Transposable Elements of the Drosophila serrata Reference Panel. PMID:33950180
Genomic patterns of structural variation among diverse genotypes of Sorghum bicolor and a potential role for deletions in local adaptation. PMID:33950177
The spontaneous mutation rate of Drosophila pseudoobscura. PMID:33950174
Analysis of Brugada syndrome loci reveals that fine-mapping clustered GWAS hits enhances the annotation of disease-relevant variants. PMID:33948580
Whole genome analysis of extensively drug resistant Mycobacterium tuberculosis strains in Peru. PMID:33947918
Metastasis is altered through multiple processes regulated by the E2F1 transcription factor. PMID:33947907
Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo. PMID:33947861
Single-cell sequencing of the small and AT-skewed genome of malaria parasites. PMID:33947449
ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas. PMID:33946962
Spatial Distribution of Private Gene Mutations in Clear Cell Renal Cell Carcinoma. PMID:33946379
The Usefulness of Cell-Based and Liquid-Based Urine Tests in Clarifying the Diagnosis and Monitoring the Course of Urothelial Carcinoma. Identification of Novel, Potentially Actionable, RB1 and ERBB2 Somatic Mutations. PMID:33946229
Copy number signature analysis tool and its application in prostate cancer reveals distinct mutational processes and clinical outcomes. PMID:33945534
Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization. PMID:33945510
Direct identification and molecular characterization of zoonotic hazards in raw milk by metagenomics using Brucella as a model pathogen. PMID:33945456
Genomic epidemiology of tuberculosis in eastern Malaysia: insights for strengthening public health responses. PMID:33945455
Experimental evolution in morbidostat reveals converging genomic trajectories on the path to triclosan resistance. PMID:33945454
Genome-wide DNA methylation analysis and biochemical responses provide insights into the initial domestication of halophyte Puccinellia tenuiflora. PMID:33945005
Vulture Genomes Reveal Molecular Adaptations Underlying Obligate Scavenging and Low Levels of Genetic Diversity. PMID:33944941
Gene Coexpression Network Reveals Highly Conserved, Well-Regulated Anti-Ageing Mechanisms in Old Ant Queens. PMID:33944936
Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses. PMID:33944920
Rampant Genome-Wide Admixture across the Heliconius Radiation. PMID:33944917
Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis. PMID:33942715
The pan-genome of the cultivated soybean (PanSoy) reveals an extraordinarily conserved gene content. PMID:33942475
A novel WT1 gene mutation in a chinese girl with denys-drash syndrome. PMID:33942367
Alternative splicing during mammalian organ development. PMID:33941934
Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands. PMID:33941929
Enhancing photosynthesis at high light levels by adaptive laboratory evolution. PMID:33941908
Population genomics provides insights into the evolution and adaptation to humans of the waterborne pathogen Mycobacterium kansasii. PMID:33941780
Fast and pervasive transcriptomic resilience and acclimation of extremely heat-tolerant coral holobionts from the northern Red Sea. PMID:33941698
Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers. PMID:33941616
Use of whole-genome sequencing to investigate a cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in emergency department personnel. PMID:33941299
Genetic analysis using targeted next-generation sequencing of sporadic Chinese patients with idiopathic dilated cardiomyopathy. PMID:33941202
Genomics of Staphylococcus aureus ocular isolates. PMID:33939761
One step forward, two steps back: Transcriptional advancements and fermentation phenomena in Actinobacillus succinogenes 130Z. PMID:33939701
A guided-inquiry investigation of genetic variants using Oxford nanopore sequencing for an undergraduate molecular biology laboratory course. PMID:33939256
Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1. PMID:33938913
Exploring the molecular content of CHO exosomes during bioprocessing. PMID:33937930
The long and the short of it: unlocking nanopore long-read RNA sequencing data with short-read differential expression analysis tools. PMID:33937765
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses. PMID:33937724
Unique Combination of Diamond-Blackfan Anemia and Lynch Syndrome in Adult Female: A Case Report. PMID:33937060
Comparison of Short-Read Sequence Aligners Indicates Strengths and Weaknesses for Biologists to Consider. PMID:33936141
Local Duplication of TIR-NBS-LRR Gene Marks Clubroot Resistance in Brassica napus cv. Tosca. PMID:33936130
New Genotype of Yersinia pestis Found in Live Rodents in Yunnan Province, China. PMID:33935990
RNA-Seq Dataset From Isolated Leukocytes Following Spontaneous Intracerebral Hemorrhage in Zebrafish Larvae. PMID:33935655
The landscape of chromatin accessibility in skeletal muscle during embryonic development in pigs. PMID:33934724
Development and testing of a combined species SNP array for the European seabass (Dicentrarchus labrax) and gilthead seabream (Sparus aurata). PMID:33933591
The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. PMID:33933450
SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductor-powered RNA-seq analyses. PMID:33932985
A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes. PMID:33931649
Whole-genome sequencing reveals rare off-target mutations in CRISPR/Cas9-edited grapevine. PMID:33931634
Genetic analysis of the "head top shape" quality trait of Chinese cabbage and its association with rosette leaf variation. PMID:33931629
The domestication of Cucurbita argyrosperma as revealed by the genome of its wild relative. PMID:33931618
Chromatin accessibility and translational landscapes of tea plants under chilling stress. PMID:33931606
A Histone-Like Nucleoid Structuring Protein Regulates Several Virulence Traits in Burkholderia multivorans. PMID:33931418
Comparative genomics of the coconut crab and other decapod crustaceans: exploring the molecular basis of terrestrial adaptation. PMID:33931033
The genomic history of the Aegean palatial civilizations. PMID:33930288
Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection. PMID:33930088
Novel insights from the Plasmodium falciparum sporozoite-specific proteome by probabilistic integration of 26 studies. PMID:33930021
BloodPAC Data Commons for Liquid Biopsy Data. PMID:33929890
Cis-regulatory dissection of cone development reveals a broad role for Otx2 and Oc transcription factors. PMID:33929509
Interannual dynamics, diversity and evolution of the virome in Sclerotinia sclerotiorum from a single crop field. PMID:33927888
A 598-bp InDel Variation in the Promoter Region of Bna.SOC1.A05 Is Predominantly Present in Winter Type Rapeseeds. PMID:33927737
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells. PMID:33927210
Decrypting bacterial polyphenol metabolism in an anoxic wetland soil. PMID:33927199
Complete Genome Sequence of a Blochmannia Endosymbiont of Colobopsis nipponica. PMID:33927044
Stepwise pathogenic evolution of Mycobacterium abscessus. PMID:33926925
Genome-wide gene expression changes of Pseudomonas veronii 1YdBTEX2 during bioaugmentation in polluted soils. PMID:33926576
nPhase: an accurate and contiguous phasing method for polyploids. PMID:33926549
Ten-eleven translocation protein 1 modulates medulloblastoma progression. PMID:33926529
The impact of cell type and context-dependent regulatory variants on human immune traits. PMID:33926512
New insights into hallux valgus by whole exome sequencing study. PMID:33926255
Characterisation of the Viral Community Associated with the Alfalfa Weevil (Hypera postica) and Its Host Plant, Alfalfa (Medicago sativa). PMID:33925168
Sorghum Brown Midrib19 (Bmr19) Gene Links Lignin Biosynthesis to Folate Metabolism. PMID:33924915
Molecular Phylogeny and Evolution of Amazon Parrots in the Greater Antilles. PMID:33924228
Transcriptome Sequence Reveals Candidate Genes Involving in the Post-Harvest Hardening of Trifoliate Yam Dioscorea dumetorum. PMID:33923758
Sex-Biased lncRNA Signature in Fetal Growth Restriction (FGR). PMID:33923632
First Bronze Age Human Mitogenomes from Calabria (Grotta Della Monaca, Southern Italy). PMID:33922908
AS-Quant: Detection and Visualization of Alternative Splicing Events with RNA-seq Data. PMID:33922891
Translational Attenuation by an Intron Retention in the 5' UTR of ENAM Causes Amelogenesis Imperfecta. PMID:33922212
Genome-Wide Identification and Expression Analysis of SOS Response Genes in Salmonella enterica Serovar Typhimurium. PMID:33921732
TILLING-by-Sequencing+ to Decipher Oil Biosynthesis Pathway in Soybeans: A New and Effective Platform for High-Throughput Gene Functional Analysis. PMID:33921707
Genome-Wide Association Study of Local Thai Indica Rice Seedlings Exposed to Excessive Iron. PMID:33921675
The MarR-Type Regulator PA3458 Is Involved in Osmoadaptation Control in Pseudomonas aeruginosa. PMID:33921535
Mapping Astrocyte Transcriptional Signatures in Response to Neuroactive Compounds. PMID:33921461
Novel Compound Heterozygous Mutation in TRAPPC9 Gene: The Relevance of Whole Genome Sequencing. PMID:33921338
A Yarrowia lipolytica Strain Engineered for Pyomelanin Production. PMID:33920006
Mapping of Genetic Locus for Leaf Trichome Formation in Chinese Cabbage Based on Bulked Segregant Analysis. PMID:33919922
Characterization of a Novel Group of Listeria Phages That Target Serotype 4b Listeria monocytogenes. PMID:33919793
Proteomic Identification and Meta-Analysis in Salvia hispanica RNA-Seq de novo Assemblies. PMID:33919777
Metabolic, Organoleptic and Transcriptomic Impact of Saccharomyces cerevisiae Genes Involved in the Biosynthesis of Linear and Substituted Esters. PMID:33919724
Novel Siphoviridae Bacteriophages Infecting Bacteroides uniformis Contain Diversity Generating Retroelement. PMID:33919474
Delineating the Tnt1 Insertion Landscape of the Model Legume Medicago truncatula cv. R108 at the Hi-C Resolution Using a Chromosome-Length Genome Assembly. PMID:33919286
Formation of Proto-Kranz in C3 Rice Induced by Spike-Stalk Injection Method. PMID:33919137
Exploring the Loci Responsible for Awn Development in Rice through Comparative Analysis of All AA Genome Species. PMID:33917982
Genome-Wide Mapping of Histone H3 Lysine 4 Trimethylation (H3K4me3) and Its Involvement in Fatty Acid Biosynthesis in Sunflower Developing Seeds. PMID:33917507
Phage Resistance Is Associated with Decreased Virulence in KPC-Producing Klebsiella pneumoniae of the Clonal Group 258 Clade II Lineage. PMID:33917365
Tumor Signature Analysis Implicates Hereditary Cancer Genes in Endometrial Cancer Development. PMID:33917078
Next Generation Sequencing Technology in the Clinic and Its Challenges. PMID:33916923
Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice. PMID:33916486
Diet-Related Alterations of Gut Bile Salt Hydrolases Determined Using a Metagenomic Analysis of the Human Microbiome. PMID:33915727
Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism. PMID:33915113
A mixture of quebracho and chestnut tannins drives butyrate-producing bacteria populations shift in the gut microbiota of weaned piglets. PMID:33914832
The genomics of rapid climatic adaptation and parallel evolution in North American house mice. PMID:33914747
Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis. PMID:33914608
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. PMID:33913810
ZC3H4 restricts non-coding transcription in human cells. PMID:33913806
Rapid and Low-Input Profiling of Histone Marks in Plants Using Nucleus CUT&Tag. PMID:33912205
Somatic mutation landscapes at single-molecule resolution. PMID:33911282
Towards complete and error-free genome assemblies of all vertebrate species. PMID:33911273
Transcription factor chromatin profiling genome-wide using uliCUT&RUN in single cells and individual blastocysts. PMID:33911257
Efficient and strand-specific profiling of replicating chromatin with enrichment and sequencing of protein-associated nascent DNA in mammalian cells. PMID:33911256
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection. PMID:33911082
Extended haplotype-phasing of long-read de novo genome assemblies using Hi-C. PMID:33911078
Cyanophage Diversity and Community Structure in Dead Zone Sediments. PMID:33910994
Vaccinia Virus Gene Acquisition through Nonhomologous Recombination. PMID:33910949
Validation and standardization of DNA extraction and library construction methods for metagenomics-based human fecal microbiome measurements. PMID:33910647
Novel manifestations of Warburg micro syndrome type 1 caused by a new splicing variant of RAB3GAP1: a case report. PMID:33910511
Variants at the ASIP locus contribute to coat color darkening in Nellore cattle. PMID:33910501
Performance evaluation of pipelines for mapping, variant calling and interval padding, for the analysis of NGS germline panels. PMID:33910496
5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer's disease. PMID:33910000
ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection. PMID:33909709
A pseudomolecule assembly of the Rocky Mountain elk genome. PMID:33909645
Insight into the introduction of domestic cattle and the process of Neolithization to the Spanish region Galicia by genetic evidence. PMID:33909617
Single-cell transcriptome and genome analyses of pituitary neuroendocrine tumors. PMID:33908609
Limited cross-species transmission and absence of mutations associated with SARS-CoV-2 adaptation in cats: A case study of infection in a small household setting. PMID:33908152
Detailed evaluation of cancer sequencing pipelines in different microenvironments and heterogeneity levels. PMID:33907494
Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer. PMID:33907296
Reevaluation of the Toxoplasma gondii and Neospora caninum genomes reveals misassembly, karyotype differences, and chromosomal rearrangements. PMID:33906964
Third-generation sequencing revises the molecular karyotype for Toxoplasma gondii and identifies emerging copy number variants in sexual recombinants. PMID:33906962
Functional Characterization of the m6A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite. PMID:33906926
M6ADD: a comprehensive database of m6A modifications in diseases. PMID:33906563
Endonuclease enrichment TAPS for cost-effective genome-wide base-resolution DNA methylation detection. PMID:33905495
Concurrent mutations associated with trastuzumab-resistance revealed by single cell sequencing. PMID:33905021
Cell division in the archaeon Haloferax volcanii relies on two FtsZ proteins with distinct functions in division ring assembly and constriction. PMID:33903747
Adaptive introgression of the beta-globin cluster in two Andean waterfowl. PMID:33903741
SARS-CoV-2 E Gene Variant Alters Analytical Sensitivity Characteristics of Viral Detection Using a Commercial Reverse Transcription-PCR Assay. PMID:33903167
Seasonal dynamics in taxonomy and function within bacterial and viral metagenomic assemblages recovered from a freshwater agricultural pond. PMID:33902740
The distribution of microbiomes and resistomes across farm environments in conventional and organic dairy herds in Pennsylvania. PMID:33902716
Impact of process temperature and organic loading rate on cellulolytic / hydrolytic biofilm microbiomes during biomethanation of ryegrass silage revealed by genome-centered metagenomics and metatranscriptomics. PMID:33902713
Whole-genome sequencing of phenotypically distinct inflammatory breast cancers reveals similar genomic alterations to non-inflammatory breast cancers. PMID:33902690
Resistance-associated substitutions and response to treatment in a chronic hepatitis C virus infected-patient: an unusual virological response case report. PMID:33902462
Draft genome of a biparental beetle species, Lethrus apterus. PMID:33902445
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. PMID:33902106
Comprehensive at-arrival transcriptomic analysis of post-weaned beef cattle uncovers type I interferon and antiviral mechanisms associated with bovine respiratory disease mortality. PMID:33901263
Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior. PMID:33901168
Translational control of gene expression by eIF2 modulates proteostasis and extends lifespan. PMID:33901016
Genomic and epigenomic active vitamin D responses in human colonic organoids. PMID:33900108
Investigating Molecular Determinants of Cancer Cell Resistance to Ionizing Radiation Through an Integrative Bioinformatics Approach. PMID:33898418
Heterogeneity of a dwarf phenotype in Dutch traditional chicken breeds revealed by genomic analyses. PMID:33897823
Dynamic Transcriptome Sequencing of Bovine Alphaherpesvirus Type 1 and Host Cells Carried Out by a Multi-Technique Approach. PMID:33897757
Genetic Diversity and Population Structure in Bryophyte With Facultative Nannandry. PMID:33897717
The First Contact of Human Dendritic Cells With Trypanosoma cruzi Reveals Response to Virus as an Unexplored Central Pathway. PMID:33897690
Phenotypic and Genomic Variability of Serial Peri-Lung Transplantation Pseudomonas aeruginosa Isolates From Cystic Fibrosis Patients. PMID:33897629
Re-evaluation of single nucleotide variants and identification of structural variants in a cohort of 45 sudden unexplained death cases. PMID:33895855
Optical maps refine the bread wheat Triticum aestivum cv. Chinese Spring genome assembly. PMID:33893684
Genetic landscape of breast cancer and mutation tracking with circulating tumor DNA in Chinese women. PMID:33893247
Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia. PMID:33893150
Extracellular and Intracellular Lanthanide Accumulation in the Methylotrophic Beijerinckiaceae Bacterium RH AL1. PMID:33893117
Comparative genomic analysis of sifakas (Propithecus) reveals selection for folivory and high heterozygosity despite endangered status. PMID:33893095
Cotton pan-genome retrieves the lost sequences and genes during domestication and selection. PMID:33892774
Genetic Architecture Underlying Nascent Speciation-The Evolution of Eurasian Pigs under Domestication. PMID:33892509
Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States. PMID:33891875
A unified atlas of CD8 T cell dysfunctional states in cancer and infection. PMID:33891860
Zika virus dysregulates the expression of astrocytic genes involved in neurodevelopment. PMID:33891593
Nested association mapping reveals the genetic architecture of spike emergence and anthesis timing in intermediate wheatgrass. PMID:33890617
High-density mapping for gray leaf spot resistance using two related tropical maize recombinant inbred line populations. PMID:33890197
First Report on the Latvian SARS-CoV-2 Isolate Genetic Diversity. PMID:33889583
Enhancement and Imputation of Peak Signal Enables Accurate Cell-Type Classification in scATAC-seq. PMID:33889181
Scrt1, a transcriptional regulator of β-cell proliferation identified by differential chromatin accessibility during islet maturation. PMID:33888791
The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation. PMID:33888695
Replication timing maintains the global epigenetic state in human cells. PMID:33888635
BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome. PMID:33888563
Modeling transcriptional regulation of model species with deep learning. PMID:33888512
An atlas of the tissue and blood metagenome in cancer reveals novel links between bacteria, viruses and cancer. PMID:33888160
Isolation and genomic characterization of five novel strains of Erysipelotrichaceae from commercial pigs. PMID:33888068
Growth genes are implicated in the evolutionary divergence of sympatric piscivorous and insectivorous rainbow trout (Oncorhynchus mykiss). PMID:33888062
Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers. PMID:33886547
Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos. PMID:33886094
Asexuality Associated with Marked Genomic Expansion of Tandemly Repeated rRNA and Histone Genes. PMID:33885820
Impact of different numbers of microsatellite markers on population genetic results using SLAF-seq data for Rhododendron species. PMID:33883608
Establishment of Culex modestus in Belgium and a Glance into the Virome of Belgian Mosquito Species. PMID:33883261
Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. PMID:33883027
Further engineering of R. toruloides for the production of terpenes from lignocellulosic biomass. PMID:33883010
AFLAP: assembly-free linkage analysis pipeline using k-mers from genome sequencing data. PMID:33883006
Dynamics of rumen gene expression, microbiome colonization, and their interplay in goats. PMID:33882826
Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity. PMID:33882319
Developmental Transcriptomics Reveals a Gene Network Driving Mimetic Color Variation in a Bumble Bee. PMID:33881508
Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines. PMID:33880552
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ. PMID:33879786
Local adaptation of Mycobacterium tuberculosis on the Tibetan Plateau. PMID:33879609
Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands. PMID:33879525
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells. PMID:33878299
The bone microenvironment invigorates metastatic seeds for further dissemination. PMID:33878291
Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae. PMID:33878104
Inherited deficiency of stress granule ZNFX1 in patients with monocytosis and mycobacterial disease. PMID:33876776
Primate phageomes are structured by superhost phylogeny and environment. PMID:33876746
On the origin of the widespread self-compatible allotetraploid Capsella bursa-pastoris (Brassicaceae). PMID:33875831
Profiling SARS-CoV-2 mutation fingerprints that range from the viral pangenome to individual infection quasispecies. PMID:33875001
The transcriptome landscapes of citrus leaf in different developmental stages. PMID:33871796
Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse. PMID:33871658
Population Bottlenecks Strongly Affect the Evolutionary Dynamics of Antibiotic Persistence. PMID:33871643
The Association of Mitochondrial Copy Number With Sarcopenia in Adult Survivors of Childhood Cancer. PMID:33871611
Unearthing LTR Retrotransposon gag Genes Co-opted in the Deep Evolution of Eukaryotes. PMID:33871607
RIL-StEp: epistasis analysis of rice recombinant inbred lines (RILs) reveals candidate interacting genes that control seed hull color and leaf chlorophyll content. PMID:33871605
Mutant Allele Frequency-Based Intra-Tumoral Genetic Heterogeneity Related to the Tumor Shrinkage Mode After Neoadjuvant Chemotherapy in Breast Cancer Patients. PMID:33869255
Extensive microbial diversity within the chicken gut microbiome revealed by metagenomics and culture. PMID:33868800
RNA-Seq-based high-resolution linkage map reveals the genetic architecture of fruiting body development in shiitake mushroom, Lentinula edodes. PMID:33868600
Unique Brewing-Relevant Properties of a Strain of Saccharomyces jurei Isolated From Ash (Fraxinus excelsior). PMID:33868204
RNA-seq reveals plant virus composition and diversity in alfalfa, thrips, and aphids in Beijing, China. PMID:33866416
Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine Liver. PMID:33866021
Population and subspecies diversity at mouse centromere satellites. PMID:33865332
Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity. PMID:33863983
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease. PMID:33863903
A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency. PMID:33863366
Loss of coordinated expression between ribosomal and mitochondrial genes revealed by comprehensive characterization of a large family with a rare Mendelian disorder. PMID:33862179
Targeted sequencing and integrative analysis to prioritize candidate genes in neurodevelopmental disorders. PMID:33860439
TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia. PMID:33860275
A total of 219 metagenome-assembled genomes of microorganisms from Icelandic marine waters. PMID:33859876
Transcriptional profile in rat muscle: down-regulation networks in acute strenuous exercise. PMID:33859869
ZNF410 represses fetal globin by singular control of CHD4. PMID:33859416
Quantitative mapping of the cellular small RNA landscape with AQRNA-seq. PMID:33859402
Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression. PMID:33859315
Identification and distribution of novel badnaviral sequences integrated in the genome of cacao (Theobroma cacao). PMID:33859254
Transcriptional profiles in Strongyloides stercoralis males reveal deviations from the Caenorhabditis sex determination model. PMID:33859232
Clinical effect and antiviral mechanism of T-705 in treating severe fever with thrombocytopenia syndrome. PMID:33859168
A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia. PMID:33859044
Host barriers to SARS-CoV-2 demonstrated by ferrets in a high-exposure domestic setting. PMID:33858941
Genome Sequences of Five SARS-CoV-2 Variants from Mumbai, India, Obtained by Nanopore Sequencing. PMID:33858931
Draft Genome Sequences of Pseudomonas syringae pv. tomato Strains J4 and J6, Isolated in Florida. PMID:33858923
Complete Genome Sequence of the Red-Pigmented Strain Serratia marcescens SCQ1 and Its Four Spontaneous Pigment Mutants. PMID:33858915
Stable high-density and maternally inherited Wolbachia infections in Anopheles moucheti and Anopheles demeilloni mosquitoes. PMID:33857432
Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes. PMID:33857427
Maize centromeric chromatin scales with changes in genome size. PMID:33857306
Human KIT+ myeloid cells facilitate visceral metastasis by melanoma. PMID:33857287
Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection. PMID:33857265
Metagenomic insights into mixotrophic denitrification facilitated nitrogen removal in a full-scale A2/O wastewater treatment plant. PMID:33857258
Use of amplicon-based sequencing for testing fetal identity and monogenic traits with Single Circulating Trophoblast (SCT) as one form of cell-based NIPT. PMID:33857205
Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination. PMID:33857129
A head-to-head comparison of ribodepletion and polyA selection approaches for C. elegans low input RNA-sequencing libraries. PMID:33856427
Comparative analysis of DNA extraction protocols for ancient soft tissue museum samples. PMID:33855818
Characterization of the first vaginal Lactobacillus crispatus genomes isolated in Brazil. PMID:33854845
Development and Analytical Validation of a Targeted Next-Generation Sequencing Panel to Detect Actionable Mutations for Targeted Therapy. PMID:33854338
H3K4me2 ChIP-Seq reveals the epigenetic landscape during mushroom formation and novel developmental regulators of Schizophyllum commune. PMID:33854169
Impact of clinical targeted sequencing on endocrine responsiveness in estrogen receptor-positive, HER2-negative metastatic breast cancer. PMID:33854152
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil. PMID:33853970
Infection of Aedes aegypti Mosquitoes with Midgut-Attenuated Sindbis Virus Reduces, but Does Not Eliminate, Disseminated Infection. PMID:33853958
Parental bias in expression and interaction of genes in the equine placenta. PMID:33853939
Transcriptome architecture reveals genetic networks of bolting regulation in spinach. PMID:33853527
Alternative splicing is a developmental switch for hTERT expression. PMID:33852895
Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms. PMID:33852859
Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form. PMID:33852858
Rapid Acquisition of High-Quality SARS-CoV-2 Genome via Amplicon-Oxford Nanopore Sequencing. PMID:33851337
VirION2: a short- and long-read sequencing and informatics workflow to study the genomic diversity of viruses in nature. PMID:33850654
Bioinformatic strategies for the analysis of genomic aberrations detected by targeted NGS panels with clinical application. PMID:33850640
Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model. PMID:33850167
Steller's sea cow genome suggests this species began going extinct before the arrival of Paleolithic humans. PMID:33850161
Moss enables high sensitivity single-nucleotide variant calling from multiple bulk DNA tumor samples. PMID:33850139
Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden. PMID:33850132
A compendium and comparative epigenomics analysis of cis-regulatory elements in the pig genome. PMID:33850120
Comparative analysis of chloroplast genomes of cultivars and wild species of sweetpotato (Ipomoea batatas [L.] Lam). PMID:33849443
Analysis of whole-genome re-sequencing data of ducks reveals a diverse demographic history and extensive gene flow between Southeast/South Asian and Chinese populations. PMID:33849442
Imprints of independent allopolyploid formations on patterns of gene expression in two sibling yarrow species (Achillea, Asteraceae). PMID:33849436
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance. PMID:33848455
Multiplexing mutation rate assessment: determining pathogenicity of Msh2 variants in Saccharomyces cerevisiae. PMID:33848333
A novel KCNQ4 gene variant (c.857A>G; p.Tyr286Cys) in an extended family with non‑syndromic deafness 2A. PMID:33846771
A combined RAD-Seq and WGS approach reveals the genomic basis of yellow color variation in bumble bee Bombus terrestris. PMID:33846496
On species delimitation, hybridization and population structure of cassava whitefly in Africa. PMID:33846476
Accessible chromatin reveals regulatory mechanisms underlying cell fate decisions during early embryogenesis. PMID:33846424
Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis. PMID:33846360
Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation. PMID:33846320
Go Get Data (GGD) is a framework that facilitates reproducible access to genomic data. PMID:33846313
Niche partitioning in the Rimicaris exoculata holobiont: the case of the first symbiotic Zetaproteobacteria. PMID:33845886
Methamphetamine-induced changes in myocardial gene transcription are sex-dependent. PMID:33845768
Genome-wide analysis in Escherichia coli unravels a high level of genetic homoplasy associated with cefotaxime resistance. PMID:33843573
Ancestral plastics exposure induces transgenerational disease-specific sperm epigenome-wide association biomarkers. PMID:33841921
Investigating the morphological and genetic divergence of arctic char (Salvelinus alpinus) populations in lakes of arctic Alaska. PMID:33841765
AutoVEM: An automated tool to real-time monitor epidemic trends and key mutations in SARS-CoV-2 evolution. PMID:33841748
"Adopt-a-Tissue" Initiative Advances Efforts to Identify Tissue-Specific Histone Marks in the Mare. PMID:33841506
Gene and Transposable Element Expression Evolution Following Recent and Past Polyploidy Events in Spartina (Poaceae). PMID:33841492
NAC Candidate Gene Marker for bgm-1 and Interaction With QTL for Resistance to Bean Golden Yellow Mosaic Virus in Common Bean. PMID:33841459
Definition of a High-Resolution Molecular Marker for Tracking the Genetic Diversity of the Harmful Algal Species Eucampia zodiacus Through Comparative Analysis of Mitochondrial Genomes. PMID:33841358
Genetic Polymorphism Drives Susceptibility Between Bacteria and Bacteriophages. PMID:33841354
Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen. PMID:33841165
Screening of novel alkaloid inhibitors for vascular endothelial growth factor in cancer cells: an integrated computational approach. PMID:33840170
Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencing. PMID:33840166
Dynamic association of the H3K64 trimethylation mark with genes encoding exported proteins in Plasmodium falciparum. PMID:33839154
Shutoff of host transcription triggers a toxin-antitoxin system to cleave phage RNA and abort infection. PMID:33838104
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. PMID:33838102
Population Genomics of the Maize Pathogen Ustilago maydis: Demographic History and Role of Virulence Clusters in Adaptation. PMID:33837781
Disruption of the MSL complex inhibits tumour maintenance by exacerbating chromosomal instability. PMID:33837287
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice. PMID:33837189
Genes Encoding Microbial Acyl Coenzyme A Binding Protein/Diazepam-Binding Inhibitor Orthologs Are Rare in the Human Gut Microbiome and Show No Links to Obesity. PMID:33837018
Synonymous mutations that regulate translation speed might play a non-negligible role in liver cancer development. PMID:33836673
Transcriptomic, proteomic and ultrastructural studies on salinity-tolerant Aedes aegypti in the context of rising sea levels and arboviral disease epidemiology. PMID:33836668
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. PMID:33836156
Myod1 and GR coordinate myofiber-specific transcriptional enhancers. PMID:33836079
Suppression of liquid-liquid phase separation by 1,6-hexanediol partially compromises the 3D genome organization in living cells. PMID:33836078
Adaptation to the dietary sugar D-tagatose via genome instability in polyploid Candida albicans cells. PMID:33836061
Mapping of a major QTL controlling plant height using a high-density genetic map and QTL-seq methods based on whole-genome resequencing in Brassica napus. PMID:33836054
SARS-CoV-2 outbreak in Iran: The dynamics of the epidemic and evidence on two independent introductions. PMID:33835709
Nanopore RNA Sequencing Analysis. PMID:33835464
Transcript Identification Through Long-Read Sequencing. PMID:33835462
RNA Editing Detection in HPC Infrastructures. PMID:33835447
Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation. PMID:33835028
NusG is an intrinsic transcription termination factor that stimulates motility and coordinates gene expression with NusA. PMID:33835023
Crucial role of Salmonella genomic island 1 master activator in the parasitism of IncC plasmids. PMID:33834206
Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA. PMID:33833465
Evidence for early dispersal of domestic sheep into Central Asia. PMID:33833423
Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family. PMID:33833268
Interpretation of allele-specific chromatin accessibility using cell state-aware deep learning. PMID:33832990
Whole-exome sequencing reveals the etiology of the rare primary hepatic mucoepidermoid carcinoma. PMID:33832503
Low-level variant calling for non-matched samples using a position-based and nucleotide-specific approach. PMID:33832433
Human naive epiblast cells possess unrestricted lineage potential. PMID:33831366
Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights. PMID:33831079
The role of a mechanistic host in maintaining arctic rabies variant distributions: Assessment of functional genetic diversity in Alaskan red fox (Vulpes vulpes). PMID:33831031
Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA. PMID:33831001
CaBagE: A Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing. PMID:33830997
Genomic characterization of small cell carcinomas of the uterine cervix. PMID:33830625
The complete chloroplast genome of Aruncus dioicus var. kamtschaticus (Rosaceae). PMID:33829101
Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. PMID:33828320
Genome-wide enhancer maps link risk variants to disease genes. PMID:33828297
The structure, function and evolution of a complete human chromosome 8. PMID:33828295
Analysis of the gene transcription patterns and DNA methylation characteristics of triploid sea cucumbers (Apostichopus japonicus). PMID:33828212
Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals. PMID:33828169
Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between human pluripotent states. PMID:33828098
Genome-Based Targeted Sequencing as a Reproducible Microbial Community Profiling Assay. PMID:33827913
Comprehensive analysis of germline mutations in northern Brazil: a panel of 16 genes for hereditary cancer-predisposing syndrome investigation. PMID:33827469
Gene expression profiles underlying aggressive behavior in the prefrontal cortex of cattle. PMID:33827428
MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation. PMID:33826889
Genotyping-by-Sequencing of the regional Pacific abalone (Haliotis discus) genomes reveals population structures and patterns of gene flow. PMID:33826655
Aedes aegypti dyspepsia encodes a novel member of the SLC16 family of transporters and is critical for reproductive fitness. PMID:33826624
Evolution of the complex transcription network controlling biofilm formation in Candida species. PMID:33825680
Sequence-based GWAS and post-GWAS analyses reveal a key role of SLC37A1, ANKH, and regulatory regions on bovine milk mineral content. PMID:33824377
Single-cell transcriptome atlas and chromatin accessibility landscape reveal differentiation trajectories in the rice root. PMID:33824350
Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. PMID:33824326
PCIP-seq: simultaneous sequencing of integrated viral genomes and their insertion sites with long reads. PMID:33823910
Functional genomics of a Spiroplasma associated with the carmine cochineals Dactylopius coccus and Dactylopius opuntiae. PMID:33823812
Genetic Barriers to Historical Gene Flow between Cryptic Species of Alpine Bumblebees Revealed by Comparative Population Genomics. PMID:33823537
Single-cell resolution of lineage trajectories in the Arabidopsis stomatal lineage and developing leaf. PMID:33823130
Choice of assemblers has a critical impact on de novo assembly of SARS-CoV-2 genome and characterizing variants. PMID:33822878
Migration through a Major Andean Ecogeographic Disruption as a Driver of Genetic and Phenotypic Diversity in a Wild Tomato Species. PMID:33822137
Population genomic analysis of Cryptococcus Brazilian isolates reveals an African type subclade distribution. PMID:33822048
Spontaneous seizures and elevated seizure susceptibility in response to somatic mutation of sodium channel Scn8a in the mouse. PMID:33822038
PopAmaranth: A population genetic genome browser for grain amaranths and their wild relatives. PMID:33822034
CASB: a concanavalin A-based sample barcoding strategy for single-cell sequencing. PMID:33821571
Simultaneous detection and mutation surveillance of SARS-CoV-2 and multiple respiratory viruses by rapid field-deployable sequencing. PMID:33821249
H2AK119ub1 guides maternal inheritance and zygotic deposition of H3K27me3 in mouse embryos. PMID:33821003
Integrative microbiomics in bronchiectasis exacerbations. PMID:33820995
Discovering multiple types of DNA methylation from bacteria and microbiome using nanopore sequencing. PMID:33820988
Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans. PMID:33820969
Microbiome assembly for sulfonamide subsistence and the transfer of genetic determinants. PMID:33820946
In Vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-Emergent Resistance to Ceftolozane-Tazobactam. PMID:33820773
Sequencing error profiles of Illumina sequencing instruments. PMID:33817639
Mink SARS-CoV-2 Infection in Poland - Short Communication. PMID:33817389
Low Diversity of Human Variation Despite Mostly Mild Functional Impact of De Novo Variants. PMID:33816556
Genome-Wide Association Identifies Risk Pathways for SAPHO Syndrome. PMID:33816493
Increasing temperature alters the within-host competition of viral strains and influences virus genetic variability. PMID:33815829
Exome-Wide Search for Genes Associated With Central Nervous System Inflammatory Demyelinating Diseases Following CHIKV Infection: The Tip of the Iceberg. PMID:33815474
Initial Insights Into the Genetic Epidemiology of SARS-CoV-2 Isolates From Kerala Suggest Local Spread From Limited Introductions. PMID:33815467
Association Mapping and Transcriptome Analysis Reveal the Genetic Architecture of Maize Kernel Size. PMID:33815440
Population Genomics of the "Arcanum" Species Group in Wild Tomatoes: Evidence for Separate Origins of Two Self-Compatible Lineages. PMID:33815438
Identification and Validation of Reference Genes in Clostridium beijerinckii NRRL B-598 for RT-qPCR Using RNA-Seq Data. PMID:33815328
Whole-genome re-sequencing data to infer historical demography and speciation processes in land snails: the study of two Candidula sister species. PMID:33813898
Single individual structural variant detection uncovers widespread hemizygosity in molluscs. PMID:33813894
Extensive genome-wide duplications in the eastern oyster (Crassostrea virginica). PMID:33813893
The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr. PMID:33811831
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection. PMID:33811809
Genome sequencing and comparative genome analysis of 6 hypervirulent Klebsiella pneumoniae strains isolated in China. PMID:33811489
A Novel Auxiliary Agarolytic Pathway Expands Metabolic Versatility in the Agar-Degrading Marine Bacterium Colwellia echini A3T. PMID:33811026
Solid Pseudopapillary Neoplasm of the Pancreas and Abdominal Desmoid Tumor in a Patient Carrying Two Different BRCA2 Germline Mutations: New Horizons from Tumor Molecular Profiling. PMID:33810291
Cranberry Proanthocyanidins and Dietary Oligosaccharides Synergistically Modulate Lactobacillus plantarum Physiology. PMID:33810188
Metabolic Capacity of the Antarctic Cyanobacterium Phormidium pseudopriestleyi That Sustains Oxygenic Photosynthesis in the Presence of Hydrogen Sulfide. PMID:33809699
Detection of Rare Germline Variants in the Genomes of Patients with B-Cell Neoplasms. PMID:33809641
Spt4 Promotes Pol I Processivity and Transcription Elongation. PMID:33809333
The Draft Genome of a Flat Peach (Prunus persica L. cv. '124 Pan') Provides Insights into Its Good Fruit Flavor Traits. PMID:33809190
Clinical Utility of Next-Generation Sequencing-Based Panel Testing under the Universal Health-Care System in Japan: A Retrospective Analysis at a Single University Hospital. PMID:33807840
Bacterial, Archaea, and Viral Transcripts (BAVT) Expression in Gynecological Cancers and Correlation with Regulatory Regions of the Genome. PMID:33807612
High Chromosomal Stability and Immortalized Totipotency Characterize Long-Term Tissue Cultures of Chinese Ginseng (Panax Ginseng). PMID:33807422
Maternal Lineages from 10-11th Century Commoner Cemeteries of the Carpathian Basin. PMID:33807111
Genomic Epidemiology of Candida auris in Qatar Reveals Hospital Transmission Dynamics and a South Asian Origin. PMID:33807036
WGS of Commensal Neisseria Reveals Acquisition of a New Ribosomal Protection Protein (MsrD) as a Possible Explanation for High Level Azithromycin Resistance in Belgium. PMID:33806962
Transcriptomic Diversity in the Livers of South African Sardines Participating in the Annual Sardine Run. PMID:33806647
An Analysis of Differentially Expressed Coding and Long Non-Coding RNAs in Multiple Models of Skeletal Muscle Atrophy. PMID:33806354
Ribosome-Profiling Reveals Restricted Post Transcriptional Expression of Antiviral Cytokines and Transcription Factors during SARS-CoV-2 Infection. PMID:33806254
Profile of Small RNAs, vDNA Forms and Viral Integrations in Late Chikungunya Virus Infection of Aedes albopictus Mosquitoes. PMID:33806250
BrLETM2 Protein Modulates Anthocyanin Accumulation by Promoting ROS Production in Turnip (Brassica rapa subsp. rapa). PMID:33805479
A Missense Mutation in the KLF7 Gene Is a Potential Candidate Variant for Congenital Deafness in Australian Stumpy Tail Cattle Dogs. PMID:33805165
Targeted Double-Stranded cDNA Sequencing-Based Phase Analysis to Identify Compound Heterozygous Mutations and Differential Allelic Expression. PMID:33804940
Selective Activation of CNS and Reference PPARGC1A Promoters Is Associated with Distinct Gene Programs Relevant for Neurodegenerative Diseases. PMID:33804860
Fast and Efficient 5'P Degradome Library Preparation for Analysis of Co-Translational Decay in Arabidopsis. PMID:33804539
Reduced Granule Cell Proliferation and Molecular Dysregulation in the Cerebellum of Lysosomal Acid Phosphatase 2 (ACP2) Mutant Mice. PMID:33804256
Combined Genome, Transcriptome and Metabolome Analysis in the Diagnosis of Childhood Cerebellar Ataxia. PMID:33804237
Candidate Markers of Olaparib Response from Genomic Data Analyses of Human Cancer Cell Lines. PMID:33803939
A Transcriptomic Approach to Understanding the Combined Impacts of Supra-Optimal Temperatures and CO2 Revealed Different Responses in the Polyploid Coffea arabica and Its Diploid Progenitor C. canephora. PMID:33803866
Genomic Analyses of Globodera pallida, A Quarantine Agricultural Pathogen in Idaho. PMID:33803698
Innate Resistance and Phosphite Treatment Affect Both the Pathogen's and Host's Transcriptomes in the Tanoak-Phytophthora ramorum Pathosystem. PMID:33803362
Characterization and Comparative Analyses of Mitochondrial Genomes in Single-Celled Eukaryotes to Shed Light on the Diversity and Evolution of Linear Molecular Architecture. PMID:33802618
Nanopore Sequencing Reveals Global Transcriptome Signatures of Mitochondrial and Ribosomal Gene Expressions in Various Human Cancer Stem-like Cell Populations. PMID:33800955
Phase Ib Trial of Copanlisib, A Phosphoinositide-3 Kinase (PI3K) Inhibitor, with Trastuzumab in Advanced Pre-Treated HER2-Positive Breast Cancer "PantHER". PMID:33799597
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development. PMID:33797837
The complete chloroplast genome of Ottelia acuminate var. crispa, an endangered aquatic herb with extremely narrow distribution. PMID:33796742
Identification of Intrinsic RNA Binding Specificity of Purified Proteins by in vitro RNA Immunoprecipitation (vitRIP). PMID:33796620
Transcriptomic and Metabolomic Analysis Revealed Roles of Yck2 in Carbon Metabolism and Morphogenesis of Candida albicans. PMID:33796481
Description of the genetic variants identified in a cohort of patients diagnosed with localized anal squamous cell carcinoma and treated with panitumumab. PMID:33795829
Presence of complete murine viral genome sequences in patient-derived xenografts. PMID:33795676
A noncanonical microRNA derived from the snaR-A noncoding RNA targets a metastasis inhibitor. PMID:33795480
H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum. PMID:33794978
Plasma membrane phylloquinone biosynthesis in nonphotosynthetic parasitic plants. PMID:33793953
Gibberellin signaling mediates lateral root inhibition in response to K+-deprivation. PMID:33793923
Identification and characterization of sorgomol synthase in sorghum strigolactone biosynthesis. PMID:33793911
Two interacting ethylene response factors regulate heat stress response. PMID:33793870
Comparative genomics of Chlamydomonas. PMID:33793842
A systems genetics approach to deciphering the effect of dosage variation on leaf morphology in Populus. PMID:33793772
Synteny-Based Genome Assembly for 16 Species of Heliconius Butterflies, and an Assessment of Structural Variation across the Genus. PMID:33792688
ASHLEYS: automated quality control for single-cell Strand-seq data. PMID:33792647
The insect-killing bacterium Photorhabdus luminescens has the lowest mutation rate among bacteria. PMID:33791681
Aedes aegypti miRNA-33 modulates permethrin induced toxicity by regulating VGSC transcripts. PMID:33790374
Longitudinal study of the scalp microbiome suggests coconut oil to enrich healthy scalp commensals. PMID:33790324
Genome-wide data implicate terminal fusion automixis in king cobra facultative parthenogenesis. PMID:33790309
Connecting structure to function with the recovery of over 1000 high-quality metagenome-assembled genomes from activated sludge using long-read sequencing. PMID:33790294
Drug resistance profile and clonality of Plasmodium falciparum parasites in Cape Verde: the 2017 malaria outbreak. PMID:33789667
Architectural Mediator subunits are differentially essential for global transcription in Saccharomyces cerevisiae. PMID:33789343
Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution. PMID:33789109
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex. PMID:33789096
Enhancer viruses for combinatorial cell-subclass-specific labeling. PMID:33789083
Genomes of the willow-galling sawflies Euura lappo and Eupontania aestiva (Hymenoptera: Tenthredinidae): a resource for research on ecological speciation, adaptation, and gall induction. PMID:33788947
Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples. PMID:33788904
Most Genomic Loci Misrepresent the Phylogeny of an Avian Radiation Because of Ancient Gene Flow. PMID:33787929
Ferulic Acid Ameliorates Alzheimer's Disease-like Pathology and Repairs Cognitive Decline by Preventing Capillary Hypofunction in APP/PS1 Mice. PMID:33786807
Protocol for comprehensive RNA sequencing analysis of murine long non-coding RNAs during aging. PMID:33786463
Metagenomics Approaches to Investigate the Gut Microbiome of COVID-19 Patients. PMID:33786001
Integration of multi-omics approaches for functional characterization of muscle related selective sweep genes in Nanchukmacdon. PMID:33785872
Molecular organization of recombinant human-Arabidopsis chromosomes in hybrid cell lines. PMID:33785802
A domestic cat whole exome sequencing resource for trait discovery. PMID:33785770
Integrated characterization of SARS-CoV-2 genome, microbiome, antibiotic resistance and host response from single throat swabs. PMID:33785729
Machine learning predicts nucleosome binding modes of transcription factors. PMID:33784978
Microarthropod contributions to fitness variation in the common moss Ceratodon purpureus. PMID:33784868
Profiling of RNA ribose methylation in Arabidopsis thaliana. PMID:33784398
Novelty and Convergence in Adaptation to Whole Genome Duplication. PMID:33783509
Comprehensive comparative genomic and microsatellite analysis of SARS, MERS, BAT-SARS, and COVID-19 coronaviruses. PMID:33782990
Mitochondrial genomes from modern and ancient Turano-Mongolian cattle reveal an ancient diversity of taurine maternal lineages in East Asia. PMID:33782560
Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low- and middle-income countries. PMID:33782558
HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia. PMID:33782403
Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium. PMID:33781205
Isotope analysis combined with DNA barcoding provide new insights into the dietary niche of khulan in the Mongolian Gobi. PMID:33780458
Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra. PMID:33779545
Expansion and persistence of antibiotic-specific resistance genes following antibiotic treatment. PMID:33779498
Reproducible, portable, and efficient ancient genome reconstruction with nf-core/eager. PMID:33777521
Effects of diethylcarbamazine and ivermectin treatment on Brugia malayi gene expression in infected gerbils (Meriones unguiculatus). PMID:33777408
Functional Network of the Long Non-coding RNA Growth Arrest-Specific Transcript 5 and Its Interacting Proteins in Senescence. PMID:33777096
Molecular Evolution and Organization of Ribosomal DNA in the Hawkweed Tribe Hieraciinae (Cichorieae, Asteraceae). PMID:33777082
Microbial predation accelerates granulation and modulates microbial community composition. PMID:33773594
High resolution genetic dissection of the major QTL for tipburn resistance in lettuce, Lactuca sativa. PMID:33772545
Transcribed germline-limited coding sequences in Oxytricha trifallax. PMID:33772542
Low-pass genome sequencing-based detection of absence of heterozygosity: validation in clinical cytogenetics. PMID:33772221
Mesonephric and mesonephric-like carcinomas of the female genital tract: molecular characterization including cases with mixed histology and matched metastases. PMID:33772212
Association between the nucleosome footprint of plasma DNA and neoadjuvant chemotherapy response for breast cancer. PMID:33772032
The human intermediate prolactin receptor is a mammary proto-oncogene. PMID:33772010
Ancient genomic time transect from the Central Asian Steppe unravels the history of the Scythians. PMID:33771866
Super hotspots and super coldspots in the repair of UV-induced DNA damage in the human genome. PMID:33771559
Molecular characteristics of Brucella melitensis isolates from humans in Qinghai Province, China. PMID:33771234
Evidence for additive and synergistic action of mammalian enhancers during cell fate determination. PMID:33770473
Genomic variation and epidemiology of SARS-CoV-2 importation and early circulation in Israel. PMID:33770098
A transcription-centric model of SNP-age interaction. PMID:33770080
Drivers of linkage disequilibrium across a species' geographic range. PMID:33770075
Inferring the Genetic Basis of Sex Determination from the Genome of a Dioecious Nightshade. PMID:33769517
Comparison of long read sequencing technologies in interrogating bacteria and fly genomes. PMID:33768248
A Fast and Efficient Single-stranded Genomic Library Preparation Method Optimized for Ancient DNA. PMID:33768239
Long insert clone experimental evidence for assembly improvement and chimeric chromosomes detection in an allopentaploid beer yeast. PMID:33768233
Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma. PMID:33768209
Genomic association with pathogen carriage in bighorn sheep (Ovis canadensis). PMID:33767816
Whole-genome analyses provide no evidence for dog introgression in Fennoscandian wolf populations. PMID:33767747
Genetic consequences of long-term small effective population size in the critically endangered pygmy hog. PMID:33767746
Using historical genome-wide DNA to unravel the confused taxonomy in a songbird lineage that is extinct in the wild. PMID:33767745
Neuronal enhancers are hotspots for DNA single-strand break repair. PMID:33767446
Successful extraction of insect DNA from recent copal inclusions: limits and perspectives. PMID:33767248
Plastid phylogenomics resolves ambiguous relationships within the orchid family and provides a solid timeframe for biogeography and macroevolution. PMID:33767214
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability. PMID:33767157
Genome Sequence of the Black Yeast-Like Strain Aureobasidium pullulans var. aubasidani CBS 100524. PMID:33766907
Draft Genome Sequences of Dysgonomonas sp. Strains GY75 and GY617, Isolated from the Hindgut of Reticulitermes flavipes. PMID:33766898
K-seq, an affordable, reliable, and open Klenow NGS-based genotyping technology. PMID:33766048
A loss-of-function mutation in RORB disrupts saltatorial locomotion in rabbits. PMID:33764968
Temporal gene regulation by p53 is associated with the rotational setting of its binding sites in nucleosomes. PMID:33764853
ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension. PMID:33764154
The complete mitochondrial genome of Douinia plicata (Lindb.) Konstant. et. Vilnet (Scapaniaceae, Jungermanniales). PMID:33763579
Complete mitochondrial genome of the H3 haplotype Argentine ant Linepithema humile (Mayr, 1868) (Formicidae; Hymenoptera). PMID:33763578
Identification of a Locus Controlling Compound Raceme Inflorescence in Mungbean [Vigna radiata (L.) R. Wilczek]. PMID:33763121
Duckweed Species Genotyping and Interspecific Hybrid Discovery by Tubulin-Based Polymorphism Fingerprinting. PMID:33763089
Dysregulation of MicroRNAs and PIWI-Interacting RNAs in a Caenorhabditis elegans Parkinson's Disease Model Overexpressing Human α-Synuclein and Influence of tdp-1. PMID:33762903
Breast tumours maintain a reservoir of subclonal diversity during expansion. PMID:33762732
The incorporation loci of H3.3K36M determine its preferential prevalence in chondroblastomas. PMID:33762579
Porcine Hemagglutinating Encephalomyelitis Virus Infection In Vivo and Ex Vivo. PMID:33762411
EGF-mediated suppression of cell extrusion during mucosal damage attenuates opportunistic fungal invasion. PMID:33761358
IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility. PMID:33761354
Tunable, division-independent control of gene activation timing by a polycomb switch. PMID:33761349
Archaeogenomic distinctiveness of the Isthmo-Colombian area. PMID:33761327
A cohesin cancer mutation reveals a role for the hinge domain in genome organization and gene expression. PMID:33760811
Phylogenetic context of Shiga toxin-producing Escherichia coli serotype O26:H11 in England. PMID:33760723
The COVIDome Explorer Researcher Portal. PMID:33758879
Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants. PMID:33758846
Identification of deleterious recessive haplotypes and candidate deleterious recessive mutations in Japanese Black cattle. PMID:33758295
Origin and diffusion of human Y chromosome haplogroup J1-M267. PMID:33758277
Functional annotations of three domestic animal genomes provide vital resources for comparative and agricultural research. PMID:33758196
Large-scale transcriptomics to dissect 2 years of the life of a fungal phytopathogen interacting with its host plant. PMID:33757516
Nanopore Sequencing Indicates That Tandem Amplification of Chromosome 20q11.21 in Human Pluripotent Stem Cells Is Driven by Break-Induced Replication. PMID:33757297
Experimental competition induces immediate and lasting effects on the neurogenome in free-living female birds. PMID:33753482
Exopolysaccharide anchoring creates an extreme resistance to sedimentation. PMID:33753470
Towards the validation of high-throughput sequencing (HTS) for routine plant virus diagnostics: measurement of variation linked to HTS detection of citrus viruses and viroids. PMID:33752714
SLIDR and SLOPPR: flexible identification of spliced leader trans-splicing and prediction of eukaryotic operons from RNA-Seq data. PMID:33752599
Molecular characterization for food safety assessment of a genetically modified late blight resistant potato: an unusual case. PMID:33751337
MiniCAFE, a CRISPR/Cas9-based compact and potent transcriptional activator, elicits gene expression in vivo. PMID:33751124
Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites. PMID:33751115
Shannon entropy as a metric for conditional gene expression in Neurospora crassa. PMID:33751112
Mutation of the imprinted gene OsEMF2a induces autonomous endosperm development and delayed cellularization in rice. PMID:33751094
Implication of TIGIT+ human memory B cells in immune regulation. PMID:33750787
Construction of competitive endogenous RNA network reveals regulatory role of long non-coding RNAs in intracranial aneurysm. PMID:33750300
A drought-responsive rice amidohydrolase is the elusive plant guanine deaminase with the potential to modulate the epigenome. PMID:33749847
Genetic Drift Dominates Genome-Wide Regulatory Evolution Following an Ancient Whole-Genome Duplication in Atlantic Salmon. PMID:33749748
Chromosome Level Assembly of the Comma Butterfly (Polygonia c-album). PMID:33749729
Genomic diversity of SARS-CoV-2 during early introduction into the Baltimore-Washington metropolitan area. PMID:33749660
Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis. PMID:33748804
Study of microbiome changes in patients with ulcerative colitis in the Central European part of Russia. PMID:33748490
Divergently Transcribed ncRNAs in Escherichia coli: Refinement of the Transcription Starts Assumes Functional Diversification. PMID:33748186
Resveratrol Mediates the Apoptosis of Triple Negative Breast Cancer Cells by Reducing POLD1 Expression. PMID:33747905
Status of CHEK2 and p53 in patients with early-onset and conventional gastric cancer. PMID:33747205
Mutational landscape and potential therapeutic targets for sporadic pancreatic neuroendocrine tumors based on target next-generation sequencing. PMID:33747156
Toward Accurate and Robust Environmental Surveillance Using Metagenomics. PMID:33747038
Genomic Selection for F1 Hybrid Breeding in Strawberry (Fragaria × ananassa). PMID:33747025
Epigenetic Variability Among Saffron Crocus (Crocus sativus L.) Accessions Characterized by Different Phenotypes. PMID:33747022
Fine Mapping of Leaf Trichome Density Revealed a 747-kb Region on Chromosome 1 in Cold-Hardy Hybrid Wine Grape Populations. PMID:33746993
Analysis of a Methanogen and an Actinobacterium Dominating the Thermophilic Microbial Community of an Electromethanogenic Biocathode. PMID:33746613
Genomic Signatures for Species-Specific Adaptation in Lake Victoria Cichlids Derived from Large-Scale Standing Genetic Variation. PMID:33744961
Hybrid assembly of an agricultural slurry virome reveals a diverse and stable community with the potential to alter the metabolism and virulence of veterinary pathogens. PMID:33743832
Design and evaluation of a custom 50K Infinium SNP array for egg-type chickens. PMID:33743497
Comparison of Brassica Genomes reveals asymmetrical gene retention between functional groups of genes in recurrent polyploidizations. PMID:33742369
ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer. PMID:33742126
Evolutionary histories and antimicrobial resistance in Shigella flexneri and Shigella sonnei in Southeast Asia. PMID:33742111
ADAS-viewer: web-based application for integrative analysis of multi-omics data in Alzheimer's disease. PMID:33741983
Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers. PMID:33741979
Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment. PMID:33741915
Stable Recombinant-Gene Expression from a Ligilactobacillus Live Bacterial Vector via Chromosomal Integration. PMID:33741626
Analysis of Different Size Fractions Provides a More Complete Perspective of Viral Diversity in a Freshwater Embayment. PMID:33741611
Sequence Analysis of 20,453 Severe Acute Respiratory Syndrome Coronavirus 2 Genomes from the Houston Metropolitan Area Identifies the Emergence and Widespread Distribution of Multiple Isolates of All Major Variants of Concern. PMID:33741335
Pre-Cambrian roots of novel Antarctic cryptoendolithic bacterial lineages. PMID:33741058
Molecular and computational approaches to map regulatory elements in 3D chromatin structure. PMID:33741028
Long-term persistence of supernumerary B chromosomes in multiple species of Astyanax fish. PMID:33740955
Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. PMID:33740397
Compromised base excision repair pathway in Mycobacterium tuberculosis imparts superior adaptability in the host. PMID:33740020
Histone chaperone CAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies. PMID:33739466
Emergence of a Neisseria gonorrhoeae clone with reduced cephalosporin susceptibility between 2014 and 2019 in Amsterdam, The Netherlands, revealed by genomic population analysis. PMID:33739419
Horizontal Gene Transfer and Gene Duplication of β-Fructofuranosidase Confer Lepidopteran Insects Metabolic Benefits. PMID:33739418
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila. PMID:33739284
Chromosome-scale genome assembly provides insights into rye biology, evolution and agronomic potential. PMID:33737754
Fine-tuning the performance of ddRAD-seq in the peach genome. PMID:33737671
Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation. PMID:33735618
POINT technology illuminates the processing of polymerase-associated intact nascent transcripts. PMID:33735606
A high-quality, chromosome-level genome assembly of the Black Soldier Fly (Hermetia illucens L.). PMID:33734373
Genetic variation in aneuploidy prevalence and tolerance across Saccharomyces cerevisiae lineages. PMID:33734361
A Pipeline for Non-model Organisms for de novo Transcriptome Assembly, Annotation, and Gene Ontology Analysis Using Open Tools: Case Study with Scots Pine. PMID:33732799
Plant ARGONAUTE Protein Immunopurification for Pathogen Cross Kingdom Small RNA Analysis. PMID:33732798
Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim. PMID:33732436
Identification of High-Confidence Structural Variants in Domesticated Rainbow Trout Using Whole-Genome Sequencing. PMID:33732289
The Immunomodulatory Effect and Clinical Efficacy of Daratumumab in a Patient With Cold Agglutinin Disease. PMID:33732266
The SWI/SNF-Related, Matrix Associated, Actin-Dependent Regulator of Chromatin A4 Core Complex Represses Respiratory Syncytial Virus-Induced Syncytia Formation and Subepithelial Myofibroblast Transition. PMID:33732255
A streamlined solution for processing, elucidating and quality control of cyclobutane pyrimidine dimer sequencing data. PMID:33731963
Temperate conditions restrict Japanese encephalitis virus infection to the mid-gut and prevents systemic dissemination in Culex pipiens mosquitoes. PMID:33731761
Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer. PMID:33731701
Phenotypic and Genomic Profiling of Staphylococcus argenteus in Canada and the United States and Recommendations for Clinical Result Reporting. PMID:33731414
Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma. PMID:33731366
A towering genome: Experimentally validated adaptations to high blood pressure and extreme stature in the giraffe. PMID:33731352
COX2 regulates senescence secretome composition and senescence surveillance through PGE2. PMID:33730589
Translational adaptation of human viruses to the tissues they infect. PMID:33730572
Global mapping of glycosylation pathways in human-derived cells. PMID:33730547
H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization. PMID:33730542
A heterochromatin inducing protein differentially recognizes self versus foreign genomes. PMID:33730092
Yeast grown in continuous culture systems can detect mutagens with improved sensitivity relative to the Ames test. PMID:33730086
High-throughput transcriptome sequencing and comparative analysis of Escherichia coli and Schizosaccharomyces pombe in respiratory and fermentative growth. PMID:33730068
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes. PMID:33730024
Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing. PMID:33727697
Mutations in hik26 and slr1916 lead to high-light stress tolerance in Synechocystis sp. PCC6803. PMID:33727624
Creation and validation of models to predict response to primary treatment in serous ovarian cancer. PMID:33727600
Recovery of complete genomes and non-chromosomal replicons from activated sludge enrichment microbial communities with long read metagenome sequencing. PMID:33727564
Uncultivated Viral Populations Dominate Estuarine Viromes on the Spatiotemporal Scale. PMID:33727395
Patient and Microbial Genomic Factors Associated with Carbapenem-Resistant Klebsiella pneumoniae Extraintestinal Colonization and Infection. PMID:33727393
Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome. PMID:33726677
Genomic imprinted genes in reciprocal hybrid endosperm of Brassica napus. PMID:33726676
Development and validation of genome-wide InDel markers with high levels of polymorphism in bitter gourd (Momordica charantia). PMID:33726664
Balancing cohesin eviction and retention prevents aberrant chromosomal interactions, Polycomb-mediated repression, and X-inactivation. PMID:33725485
Extreme diversification driven by parallel events of massive loss of heterozygosity in the hybrid lineage of Candida albicans. PMID:33724404
Seroconversion stages COVID19 into distinct pathophysiological states. PMID:33724185
Ancient DNA reveals the lost domestication history of South American camelids in Northern Chile and across the Andes. PMID:33724183
Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells. PMID:33724181
Cell-free DNA methylome profiling by MBD-seq with ultra-low input. PMID:33724157
ZNF91 deletion in human embryonic stem cells leads to ectopic activation of SVA retrotransposons and up-regulation of KRAB zinc finger gene clusters. PMID:33722937
Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data. PMID:33722935
Transcription initiation mapping in 31 bovine tissues reveals complex promoter activity, pervasive transcription, and tissue-specific promoter usage. PMID:33722934
Systemic GFP silencing is associated with high transgene expression in Nicotiana benthamiana. PMID:33720987
Transmission, adaptation and geographical spread of the Pseudomonas aeruginosa Liverpool epidemic strain. PMID:33720817
Discovery of Novel Herpes Simplexviruses in Wild Gorillas, Bonobos, and Chimpanzees Supports Zoonotic Origin of HSV-2. PMID:33720357
Asexual Experimental Evolution of Yeast Does Not Curtail Transposable Elements. PMID:33720342
Genomic region associated with pod color variation in pea (Pisum sativum). PMID:33720317
Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. PMID:33720008
A Major Locus on Wheat Chromosome 7B Associated With Late-Maturity α-Amylase Encodes a Putative ent-Copalyl Diphosphate Synthase. PMID:33719315
Using Breeding Populations With a Dual Purpose: Cultivar Development and Gene Mapping-A Case Study Using Resistance to Common Bacterial Blight in Dry Bean (Phaseolus vulgaris L.). PMID:33719292
Clinical application of an NGS-based method in the preimplantation genetic testing for Duchenne muscular dystrophy. PMID:33719023
The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress. PMID:33718883
Mutational signatures associated with exposure to carcinogenic microplastic compounds bisphenol A and styrene oxide. PMID:33718875
The complete mitochondrial genome of Scapania ampliata Steph., 1897 (Scapaniaceae, Jungermanniales). PMID:33718609
Data on the polymorphic sites in the chloroplast genomes of seven perennial Helianthus species. PMID:33718552
Higher-Order Chromatin Structures of Chromosomally Integrated HHV-6A Predict Integration Sites. PMID:33718266
Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma. PMID:33718253
Holocene chloroplast genetic variation of shrubs (Alnus alnobetula, Betula nana, Salix sp.) at the siberian tundra-taiga ecotone inferred from modern chloroplast genome assembly and sedimentary ancient DNA analyses. PMID:33717447
Evolution and Expression of the Immune System of a Facultatively Anadromous Salmonid. PMID:33717060
Identification of Natural Antisense Transcripts in Mouse Brain and Their Association With Autism Spectrum Disorder Risk Genes. PMID:33716665
Evidence of gene nucleotide composition favoring replication and growth in a fastidious plant pathogen. PMID:33715000
Evolutionary Contribution of Duplicated Genes to Genome Evolution in the Ginseng Species Complex. PMID:33713106
Auxin signaling and vascular cambium formation enable storage metabolism in cassava tuberous roots. PMID:33712830
Integration of high-density genetic mapping with transcriptome analysis uncovers numerous agronomic QTL and reveals candidate genes for the control of tillering in sorghum. PMID:33712819
Facile accelerated specific therapeutic (FAST) platform develops antisense therapies to counter multidrug-resistant bacteria. PMID:33712689
Aptardi predicts polyadenylation sites in sample-specific transcriptomes using high-throughput RNA sequencing and DNA sequence. PMID:33712618
Protein context shapes the specificity of SH3 domain-mediated interactions in vivo. PMID:33712617
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions. PMID:33712587
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes. PMID:33712570
The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation. PMID:33712472
Atoh7-independent specification of retinal ganglion cell identity. PMID:33712461
A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cells. PMID:33712417
Somatic variants for seed and fruit set in grapevine. PMID:33711928
Complete chloroplast genome features and phylogenetic analysis of Eruca sativa (Brassicaceae). PMID:33711072
Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22. PMID:33711009
Comparative analysis of 7 short-read sequencing platforms using the Korean Reference Genome: MGI and Illumina sequencing benchmark for whole-genome sequencing. PMID:33710328
Long-read sequence assembly: a technical evaluation in barley. PMID:33710295
A novel machine learning approach (svmSomatic) to distinguish somatic and germline mutations using next-generation sequencing data. PMID:33709636
Comparative transcriptomics highlights convergent evolution of energy metabolic pathways in group-living spiders. PMID:33709634
High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders. PMID:33709208
miR-4477b gene as a novel pathogenic mutation occurring during the transformation of colorectal adenoma into colorectal cancer. PMID:33708425
Selective Sweeps Uncovering the Genetic Basis of Horn and Adaptability Traits on Fine-Wool Sheep in China. PMID:33708236
Major QTLs, qARO1 and qARO9, Additively Regulate Adaxial Leaf Rolling in Rice. PMID:33708231
Single Cell RNA-Seq and Machine Learning Reveal Novel Subpopulations in Low-Grade Inflammatory Monocytes With Unique Regulatory Circuits. PMID:33708217
Pseudomonas aeruginosa PA80 is a cystic fibrosis isolate deficient in RhlRI quorum sensing. PMID:33707533
Development of the VISAGE enhanced tool and statistical models for epigenetic age estimation in blood, buccal cells and bones. PMID:33707346
Coding-Complete Genome Sequences and Mutation Profiles of Nine SARS-CoV-2 Strains Detected from COVID-19 Patients in Bangladesh. PMID:33707329
SIRT3 consolidates heterochromatin and counteracts senescence. PMID:33706382
Kozak Sequence Acts as a Negative Regulator for De Novo Transcription Initiation of Newborn Coding Sequences in the Plant Genome. PMID:33705557
Transcriptome analysis reveals defense-related genes and pathways against Xanthomonas campestris pv. vesicatoria in pepper (Capsicum annuum L.). PMID:33705404
aniFOUND: analysing the associated proteome and genomic landscape of the repaired nascent non-replicative chromatin. PMID:33693861
Long-read sequencing and de novo genome assemblies reveal complex chromosome end structures caused by telomere dysfunction at the single nucleotide level. PMID:33693840
Predicted Input of Uncultured Fungal Symbionts to a Lichen Symbiosis from Metagenome-Assembled Genomes. PMID:33693712
SOX9 modulates cancer biomarker and cilia genes in pancreatic cancer. PMID:33693707
Endometrium On-a-Chip Reveals Insulin- and Glucose-induced Alterations in the Transcriptome and Proteomic Secretome. PMID:33693651
Megadepth: efficient coverage quantification for BigWigs and BAMs. PMID:33693500
Genome-Scale Phylogenetic and Population Genetic Studies Provide Insight Into Introgression and Adaptive Evolution of Takifugu Species in East Asia. PMID:33692829
Characterization of SALL2 Gene Isoforms and Targets Across Cell Types Reveals Highly Conserved Networks. PMID:33692826
A high-resolution protein architecture of the budding yeast genome. PMID:33692541
Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans. PMID:33692492
Genomic Epidemiology of CC30 Methicillin-Resistant Staphylococcus aureus Strains from Argentina Reveals Four Major Clades with Distinctive Genetic Features. PMID:33692199
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery. PMID:33691136
Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial. PMID:33691122
Most non-canonical proteins uniquely populate the proteome or immunopeptidome. PMID:33691108
Incorporation of DNA methylation into eQTL mapping in African Americans. PMID:33691021
Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil. PMID:33688664
Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity. PMID:33688077
Direct Nanopore Sequencing of mRNA Reveals Landscape of Transcript Isoforms in Apicomplexan Parasites. PMID:33688018
The Transcription Factor Pdr802 Regulates Titan Cell Formation and Pathogenicity of Cryptococcus neoformans. PMID:33688010
Limited Evidence for Parallel Evolution Among Desert-Adapted Peromyscus Deer Mice. PMID:33686424
Stepwise chromatin and transcriptional acquisition of an intraepithelial lymphocyte program. PMID:33686285
Genome-wide investigation identifies a rare copy-number variant burden associated with human spina bifida. PMID:33686259
Genomic insights into the host specific adaptation of the Pneumocystis genus. PMID:33686174
Deep learning-based enhancement of epigenomics data with AtacWorks. PMID:33686069
Missense Mutations in the CrrB Protein Mediate Odilorhabdin Derivative Resistance in Klebsiella pneumoniae. PMID:33685902
Genetic variation and microRNA targeting of A-to-I RNA editing fine tune human tissue transcriptomes. PMID:33685485
De novo identification and targeted sequencing of SSRs efficiently fingerprints Sorghum bicolor sub-population identity. PMID:33684158
Identification of a putative candidate gene encoding 7-dehydrocholesterol reductase involved in brassinosteroids biosynthesis for compact plant architecture in Cucumber (Cucumis sativus L.). PMID:33683399
Assessing the regulatory potential of transposable elements using chromatin accessibility profiles of maize transposons. PMID:33683350
Analysis of a small outbreak of Shiga toxin-producing Escherichia coli O157:H7 using long-read sequencing. PMID:33683192
Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor. PMID:33682422
Chromosome-scale inference of hybrid speciation and admixture with convolutional neural networks. PMID:33682305
Extensive Genome-Wide Phylogenetic Discordance Is Due to Incomplete Lineage Sorting and Not Ongoing Introgression in a Rapidly Radiated Bryophyte Genus. PMID:33681996
Transcriptomic data of Clozapine-treated Ngn2-induced Human Excitatory Neurons. PMID:33681435
Composition and distribution of fish environmental DNA in an Adirondack watershed. PMID:33680576
New Insights Into Mitochondrial DNA Reconstruction and Variant Detection in Ancient Samples. PMID:33679884
Identification of Promising RILs for High Grain Zinc Through Genotype × Environment Analysis and Stable Grain Zinc QTL Using SSRs and SNPs in Rice (Oryza sativa L.). PMID:33679823
Transcriptional Profiling of STAT1 Gain-of-Function Reveals Common and Mutation-Specific Fingerprints. PMID:33679782
Methylation of rRNA as a host defense against rampant group II intron retrotransposition. PMID:33678171
Reproductive activation in honeybee (Apis mellifera) workers protects against abiotic and biotic stress. PMID:33678021
The effect of environmental stress on ageing in a termite species with low social complexity. PMID:33678015
The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health. PMID:33677570
Whole-genome resequencing reveals genetic characteristics of different duck breeds from the Guangxi region in China. PMID:33677537
RNA-SeQC 2: Efficient RNA-seq quality control and quantification for large cohorts. PMID:33677499
Accurate, ultra-low coverage genome reconstruction and association studies in Hybrid Swarm mapping populations. PMID:33677482
SomatoSim: precision simulation of somatic single nucleotide variants. PMID:33676403
Characterization of axolotl lampbrush chromosomes by fluorescence in situ hybridization and immunostaining. PMID:33675804
Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation. PMID:33675667
Comparative analysis of chloroplast genomes of kenaf cytoplasmic male sterile line and its maintainer line. PMID:33674697
Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription. PMID:33674598
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE. PMID:33674594
Multi-cell type gene coexpression network analysis reveals coordinated interferon response and cross-cell type correlations in systemic lupus erythematosus. PMID:33674349
Genetic Architecture Underlying the Metabolites of Chlorogenic Acid Biosynthesis in Populus tomentosa. PMID:33673666
Comparative Transcriptome Profile between Iberian Pig Varieties Provides New Insights into Their Distinct Fat Deposition and Fatty Acids Content. PMID:33673436
Metatranscriptome Analysis of Sympatric Bee Species Identifies Bee Virus Variants and a New Virus, Andrena-Associated Bee Virus-1. PMID:33673324
Transcriptome Analysis Reveals the Genes Involved in Bifidobacterium Longum FGSZY16M3 Biofilm Formation. PMID:33672820
Tracking Reservoirs of Antimicrobial Resistance Genes in a Complex Microbial Community Using Metagenomic Hi-C: The Case of Bovine Digital Dermatitis. PMID:33672258
Dengue Virus Serotype 2 Intrahost Diversity in Patients with Different Clinical Outcomes. PMID:33672226
Rare Recurrent Variants in Noncoding Regions Impact Attention-Deficit Hyperactivity Disorder (ADHD) Gene Networks in Children of both African American and European American Ancestry. PMID:33671795
Identification and Characterization of the Most Common Genetic Variant Responsible for Acephalic Spermatozoa Syndrome in Men Originating from North Africa. PMID:33671757
NGS-Based Application for Routine Non-Invasive Pre-Implantation Genetic Assessment in IVF. PMID:33671014
Whole Locus Sequencing Identifies a Prevalent Founder Deep Intronic RPGRIP1 Pathologic Variant in the French Leber Congenital Amaurosis Cohort. PMID:33670832
Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes. PMID:33670420
Population Genomics of American Mink Using Whole Genome Sequencing Data. PMID:33670138
A Deadly Cargo: Gene Repertoire of Cytotoxic Effector Proteins in the Camelidae. PMID:33669939
Development of a 76k Alpaca (Vicugna pacos) Single Nucleotide Polymorphisms (SNPs) Microarray. PMID:33669871
A Population Genomic Investigation of Immune Cell Diversity and Phagocytic Capacity in a Butterfly. PMID:33669297
In Vitro Reassortment between Endemic Bluetongue Viruses Features Global Shifts in Segment Frequencies and Preferred Segment Combinations. PMID:33669284
A Linkage-Based Genome Assembly for the Mosquito Aedes albopictus and Identification of Chromosomal Regions Affecting Diapause. PMID:33669192
The RNAi Mechanism Regulates a New Exonuclease Gene Involved in the Virulence of Mucorales. PMID:33668930
Application of Genomics to Understand Salt Tolerance in Lentil. PMID:33668850
Analysis of Human Gut Microbiome: Taxonomy and Metabolic Functions in Thai Adults. PMID:33668840
L-Alanine Prototrophic Suppressors Emerge from L-Alanine Auxotroph through Stress-Induced Mutagenesis in Escherichia coli. PMID:33668720
Genome-Wide Association Mapping Unravels the Genetic Control of Seed Vigor under Low-Temperature Conditions in Rapeseed (Brassica napus L.). PMID:33668258
Identification of Host Factors Associated with the Development of Equine Herpesvirus Myeloencephalopathy by Transcriptomic Analysis of Peripheral Blood Mononuclear Cells from Horses. PMID:33668216
Emergence and diversification of a highly invasive chestnut pathogen lineage across southeastern Europe. PMID:33666552
Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants. PMID:33666172
High-performance method for identification of super enhancers from ChIP-Seq data with configurable cloud virtual machines. PMID:33665151
Extremely low nucleotide diversity among thirty-six new chloroplast genome sequences from Aldama (Heliantheae, Asteraceae) and comparative chloroplast genomics analyses with closely related genera. PMID:33665028
Comparison of anadromous and landlocked Atlantic salmon genomes reveals signatures of parallel and relaxed selection across the Northern Hemisphere. PMID:33664787
Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (Canis lupus). PMID:33664786
Identification of Predictor Genes for Feed Efficiency in Beef Cattle by Applying Machine Learning Methods to Multi-Tissue Transcriptome Data. PMID:33664767
Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics. PMID:33664507
Population genomics and conservation management of a declining tropical rodent. PMID:33664461
Gene expression for secondary metabolite biosynthesis in hop (Humulus lupulus L.) leaf lupulin glands exposed to heat and low-water stress. PMID:33664420
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos. PMID:33664268
A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution. PMID:33664263
Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure. PMID:33664261
Complete Genome Sequence of Peptacetobacter (Clostridium) hiranonis Strain DGF055142, Isolated from Dog Feces from Flagstaff, Arizona, USA, 2019. PMID:33664150
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses. PMID:33664060
simATAC: a single-cell ATAC-seq simulation framework. PMID:33663563
Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data from Chinese Glioma Patients. PMID:33662628
Cas9 deactivation with photocleavable guide RNAs. PMID:33662274
Complete minicircle genome of Leptomonas pyrrhocoris reveals sources of its non-canonical mitochondrial RNA editing events. PMID:33660779
TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei. PMID:33660774
ATM controls meiotic DNA double-strand break formation and recombination and affects synaptonemal complex organization in plants. PMID:33659989
Protocol for assay of transposase accessible chromatin sequencing in non-model species. PMID:33659905
Whole-genome Identification of Transcriptional Start Sites by Differential RNA-seq in Bacteria. PMID:33659416
Enhanced limonene production in a fast-growing cyanobacterium through combinatorial metabolic engineering. PMID:33659180
Delineation of Mitochondrial DNA Variants From Exome Sequencing Data and Association of Haplogroups With Obesity in Kuwait. PMID:33659027
Anaerobic endosymbiont generates energy for ciliate host by denitrification. PMID:33658719
MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche. PMID:33658717
The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity. PMID:33658714
Bromodomain protein BRDT directs ΔNp63 function and super-enhancer activity in a subset of esophageal squamous cell carcinomas. PMID:33658703
Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells. PMID:33658609
Predicting transcriptional responses to cold stress across plant species. PMID:33658387
Segment-specific kinetics of mRNA, cRNA and vRNA accumulation during influenza infection. PMID:33658346
Whole-Genome Enrichment and Sequencing of Chlamydia trachomatis Directly from Patient Clinical Vaginal and Rectal Swabs. PMID:33658279
A Spontaneous rapZ Mutant Impairs Infectivity of Lytic Bacteriophage vB_EcoM_JS09 against Enterotoxigenic Escherichia coli. PMID:33658278
Accurate and sensitive detection of microbial eukaryotes from whole metagenome shotgun sequencing. PMID:33658077
Development, maturation, and maintenance of human prostate inferred from somatic mutations. PMID:33657416
A novel family of secreted insect proteins linked to plant gall development. PMID:33657407
Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts. PMID:33657379
The structure and diversity of strain-level variation in vaginal bacteria. PMID:33656436
ATAC-seq on Sorted Adult Mouse Neurons. PMID:33654878
Yeast Single-cell RNA-seq, Cell by Cell and Step by Step. PMID:33654857
Iron limitation by transferrin promotes simultaneous cheating of pyoverdine and exoprotease in Pseudomonas aeruginosa. PMID:33654265
Altered metabolic and inflammatory transcriptomics after cardiac surgery in neonates with congenital heart disease. PMID:33654130
Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response. PMID:33654095
Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase (pks) Island. PMID:33653937
Genetic diversity and natural selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium falciparum on Bioko Island, Equatorial Guinea and global comparative analysis. PMID:33653360
Identifying the unique characteristics of the Chinese indigenous pig breeds in the Yangtze River Delta region for precise conservation. PMID:33653278
Urinary Nucleic Acid in Tumor: Bioinformatics Approaches. PMID:33651354
Conserved co-functional network between maize and Arabidopsis aid in the identification of seed defective genes in maize. PMID:33651300
Enrichment of novel Verrucomicrobia, Bacteroidetes, and Krumholzibacteria in an oxygen-limited methane- and iron-fed bioreactor inoculated with Bothnian Sea sediments. PMID:33650794
Genomic epidemiology of COVID-19 in care homes in the east of England. PMID:33650490
Transcription factor competition at the γ-globin promoters controls hemoglobin switching. PMID:33649594
Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens. PMID:33649593
Genome editing reveals fitness effects of a gene for sexual dichromatism in Sulawesian fishes. PMID:33649298
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions. PMID:33649193
Increased Alu RNA processing in Alzheimer brains is linked to gene expression changes. PMID:33645898
Activation of endogenous retroviruses during brain development causes an inflammatory response. PMID:33644903
The complete mitochondrial genome of the far Eastern myotis: Myotis bombinus Thomas, 1906 in mainland of Korea (Chiroptera, Vespertilionidae). PMID:33644388
A-to-I RNA Editing in Cancer: From Evaluating the Editing Level to Exploring the Editing Effects. PMID:33643923
Association of T2/S-RNase With Self-Incompatibility of Japanese Citrus Accessions Examined by Transcriptomic, Phylogenetic, and Genetic Approaches. PMID:33643366
Temperature Stress Induces Shift From Co-Existence to Competition for Organic Carbon in Microalgae-Bacterial Photobioreactor Community - Enabling Continuous Production of Microalgal Biomass. PMID:33643237
Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways. PMID:33643049
Utility of whole-genome sequencing during an investigation of multiple foodborne outbreaks of Shigella sonnei. PMID:33641696
Binge-like ethanol drinking activates anaplastic lymphoma kinase signaling and increases the expression of STAT3 target genes in the mouse hippocampus and prefrontal cortex. PMID:33641239
Immune profiles of male giant panda (Ailuropoda melanoleuca) during the breeding season. PMID:33639852
Genetic etiology study of four Chinese families with two nonsyndromic deaf children in succession by targeted next-generation sequencing. PMID:33638616
Uncovering candidate genes involved in photosynthetic capacity using unexplored genetic variation in Spring Wheat. PMID:33638599
A single QTL with large effect is associated with female functional virginity in an asexual parasitoid wasp. PMID:33638236
A molecular quantitative trait locus map for osteoarthritis. PMID:33637762
Retroviral integrations contribute to elevated host cancer rates during germline invasion. PMID:33637755
Chromatin information content landscapes inform transcription factor and DNA interactions. PMID:33637709
Optimization of whole-genome sequencing of Plasmodium falciparum from low-density dried blood spot samples. PMID:33637093
In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions. PMID:33636132
In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer. PMID:33636129
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs. PMID:33636127
Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors. PMID:33635929
BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair‡. PMID:33634895
SARS-CoV-2 Early Screening at the Point of Entry: Travelers From Bangladesh to Italy-July 2020. PMID:33633786
High diversity, inbreeding and a dynamic Pleistocene demographic history revealed by African buffalo genomes. PMID:33633171
Haplotype-resolved diverse human genomes and integrated analysis of structural variation. PMID:33632895
ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks. PMID:33631799
Pervasive transmission of E484K and emergence of VUI-NP13L with evidence of SARS-CoV-2 co-infection events by two different lineages in Rio Grande do Sul, Brazil. PMID:33631222
Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants. PMID:33631116
Alternative RNA structures formed during transcription depend on elongation rate and modify RNA processing. PMID:33631106
Population structure and evolution of resistance to acetolactate synthase (ALS)-inhibitors in Amaranthus tuberculatus in Italy. PMID:33631029
Pervasive Genomic Signatures of Local Adaptation to Altitude Across Highland Specialist Andean Hummingbird Populations. PMID:33631009
Construction of a reference transcriptome for the analysis of male sterility in sugi (Cryptomeria japonica D. Don) focusing on MALE STERILITY 1 (MS1). PMID:33630910
Using prototyping to choose a bioinformatics workflow management system. PMID:33630841
OsPRR37 Alternatively Promotes Heading Date Through Suppressing the Expression of Ghd7 in the Japonica Variety Zhonghua 11 under Natural Long-Day Conditions. PMID:33630174
NK/ILC1 cells mediate neuroinflammation and brain pathology following congenital CMV infection. PMID:33630019
Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile. PMID:33629931
Complete mitochondrial genome of the acrobat ant Crematogaster teranishii Santschi, 1930 (Formicidae; Hymenoptera). PMID:33628942
The complete chloroplast genome of Zoysia matrella (L.) Merr. isolated in Korea (Poaceae): investigation of intraspecific variations on chloroplast genomes. PMID:33628934
Complete mitochondrial genome of the jet ant Lasius spathepus Wheeler, W.M., 1910 (Formicidae; Hymenoptera). PMID:33628905
Evaluation of full-length nanopore 16S sequencing for detection of pathogens in microbial keratitis. PMID:33628638
Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes. PMID:33628342
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome. PMID:33627664
QTL mapping of PEG-induced drought tolerance at the early seedling stage in sesame using whole genome re-sequencing. PMID:33626101
Molecular diagnosis of scabies using a novel probe-based polymerase chain reaction assay targeting high-copy number repetitive sequences in the Sarcoptes scabiei genome. PMID:33626043
Biases in Demographic Modeling Affect Our Understanding of Recent Divergence. PMID:33624816
A streamlined clinical metagenomic sequencing protocol for rapid pathogen identification. PMID:33623127
Predicting dynamic cellular protein-RNA interactions by deep learning using in vivo RNA structures. PMID:33623109
A synergetic effect of BARD1 mutations on tumorigenesis. PMID:33623049
Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014-2017. PMID:33622486
cfDNA deconvolution via NIPT of a pregnant woman after bone marrow transplant and donor egg IVF. PMID:33622405
Strain heterogeneity, cooccurrence network, taxonomic composition and functional profile of the healthy ocular surface microbiome. PMID:33622400
Discovery of novel community-relevant small proteins in a simplified human intestinal microbiome. PMID:33622394
An early dog from southeast Alaska supports a coastal route for the first dog migration into the Americas. PMID:33622130
A tale of two fish: Comparative transcriptomics of resistant and susceptible steelhead following exposure to Ceratonova shasta highlights differences in parasite recognition. PMID:33621237
Parallel Genomic Changes Drive Repeated Evolution of Placentas in Live-Bearing Fish. PMID:33620468
Genomic epidemiology of a Cryptococcus neoformans case cluster in Glasgow, Scotland, 2018. PMID:33620303
Accurate single-cell genotyping utilizing information from the local genome territory. PMID:33619552
Genome sequences of Tropheus moorii and Petrochromis trewavasae, two eco-morphologically divergent cichlid fishes endemic to Lake Tanganyika. PMID:33619328
Uniform genomic data analysis in the NCI Genomic Data Commons. PMID:33619257
Gene expression in tonsils in swine following infection with porcine reproductive and respiratory syndrome virus. PMID:33618723
RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila. PMID:33617535
Ancient and recent introgression shape the evolutionary history of pollinator adaptation and speciation in a model monkeyflower radiation (Mimulus section Erythranthe). PMID:33617525
Horizontal chromosome transfer and independent evolution drive diversification in Fusarium oxysporum f. sp. fragariae. PMID:33616938
A long reads-based de-novo assembly of the genome of the Arlee homozygous line reveals chromosomal rearrangements in rainbow trout. PMID:33616628
Complex histories of gene flow and a mitochondrial capture event in a nonsister pair of birds. PMID:33615597
Generation of Monogenic Candidate Genes for Human Nephrotic Syndrome Using 3 Independent Approaches. PMID:33615071
Insights into adaption and growth evolution: a comparative genomics study on two distinct cattle breeds from Northern and Southern China. PMID:33614243
Identification of novel avian and mammalian deltaviruses provides new insights into deltavirus evolution. PMID:33614159
The population genetics of nonmigratory Allen's Hummingbird (Selasphorus sasin sedentarius) following a recent mainland colonization. PMID:33614008
Next-Generation Sequencing for Molecular Diagnosis of Cystic Fibrosis in a Brazilian Cohort. PMID:33613790
p53 expression confers sensitivity to 5-fluorouracil via distinct chromatin accessibility dynamics in human colorectal cancer. PMID:33613715
Analysis of Structural Variants Reveal Novel Selective Regions in the Genome of Meishan Pigs by Whole Genome Sequencing. PMID:33613628
Distinguishing HapMap Accessions Through Recursive Set Partitioning in Hierarchical Decision Trees. PMID:33613609
Redistribution of Meiotic Crossovers Along Wheat Chromosomes by Virus-Induced Gene Silencing. PMID:33613593
Quantitative Trait Locus Mapping and Identification of Candidate Genes Controlling Flowering Time in Brassica napus L. PMID:33613591
Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia. PMID:33613545
Word Entropy-Based Approach to Detect Highly Variable Genetic Markers for Bacterial Genotyping. PMID:33613503
Emergence of fosA3 and bla CTX-M- 14 in Multidrug-Resistant Citrobacter freundii Isolates From Flowers and the Retail Environment in China. PMID:33613474
Synergistic epistasis enhances the co-operativity of mutualistic interspecies interactions. PMID:33612833
Chromosome-scale assembly of the genome of Salix dunnii reveals a male-heterogametic sex determination system on chromosome 7. PMID:33609314
Identification of QTLs associated with the anaerobic germination potential using a set of Oryza nivara introgression lines. PMID:33609225
Tolerance engineering in Deinococcus geothermalis by heterologous efflux pumps. PMID:33608597
Hologenome analysis reveals dual symbiosis in the deep-sea hydrothermal vent snail Gigantopelta aegis. PMID:33608555
Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension. PMID:33608545
Seafloor Incubation Experiment with Deep-Sea Hydrothermal Vent Fluid Reveals Effect of Pressure and Lag Time on Autotrophic Microbial Communities. PMID:33608294
PKA Cα subunit mutation triggers caspase-dependent RIIβ subunit degradation via Ser114 phosphorylation. PMID:33608270
ReSeq simulates realistic Illumina high-throughput sequencing data. PMID:33608040
Massive expansion of human gut bacteriophage diversity. PMID:33606979
N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay. PMID:33605073
GW-SEM 2.0: Efficient, Flexible, and Accessible Multivariate GWAS. PMID:33604756
De novo whole-genome assembly and resequencing resources for the roan (Hippotragus equinus), an iconic African antelope. PMID:33604669
Multivariate linear mixed model enhanced the power of identifying genome-wide association to poplar tree heights in a randomized complete block design. PMID:33604666
Base-resolution models of transcription-factor binding reveal soft motif syntax. PMID:33603233
Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. PMID:33603002
A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver. PMID:33602873
SARS-CoV-2 genomic diversity and the implications for qRT-PCR diagnostics and transmission. PMID:33602693
Taxonomic and functional analyses of intact microbial communities thriving in extreme, astrobiology-relevant, anoxic sites. PMID:33602336
LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions. PMID:33602314
Assessment of heterosis based on parental genetic distance estimated with SSR and SNP markers in upland cotton (Gossypium hirsutum L.). PMID:33602146
Genome-wide association studies detects candidate genes for wool traits by re-sequencing in Chinese fine-wool sheep. PMID:33602144
A simple method to estimate the in-house limit of detection for genetic mutations with low allele frequencies in whole-exome sequencing analysis by next-generation sequencing. PMID:33602132
Loss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation. PMID:33600773
Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition. PMID:33600438
Genetic Dissection of a Precocious Phenotype in Male Tiger Pufferfish (Takifugu rubripes) using Genotyping by Random Amplicon Sequencing, Direct (GRAS-Di). PMID:33599909
Rapid divergence of the male reproductive proteins in the Drosophila dunni group and implications for postmating incompatibilities between species. PMID:33599779
High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox. PMID:33599612
Million-year-old DNA sheds light on the genomic history of mammoths. PMID:33597750
Selective elimination of immunosuppressive T cells in patients with multiple myeloma. PMID:33597728
CD4+ T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities. PMID:33597588
Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells. PMID:33597549
Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution. PMID:33597547
Expanded catalog of microbial genes and metagenome-assembled genomes from the pig gut microbiome. PMID:33597514
Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype. PMID:33597172
Tumor immunogenomic signatures improve a prognostic model of melanoma survival. PMID:33596955
Genome-wide identification and gene-editing of pigment transporter genes in the swallowtail butterfly Papilio xuthus. PMID:33596834
Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M. PMID:33596418
High throughput detection and genetic epidemiology of SARS-CoV-2 using COVIDSeq next-generation sequencing. PMID:33596239
Genetic loci mediating circadian clock output plasticity and crop productivity under barley domestication. PMID:33595846
Transposable Element Landscape in Drosophila Populations Selected for Longevity. PMID:33595657
A Reference Genome Assembly of American Bison, Bison bison bison. PMID:33595645
HTSlib: C library for reading/writing high-throughput sequencing data. PMID:33594436
Agarose-resolvable InDel markers based on whole genome re-sequencing in cucumber. PMID:33594240
Environmental palaeogenomic reconstruction of an Ice Age algal population. PMID:33594237
A Heterogeneously Expressed Gene Family Modulates the Biofilm Architecture and Hypoxic Growth of Aspergillus fumigatus. PMID:33593969
Tracking the Emergence of Azithromycin Resistance in Multiple Genotypes of Typhoidal Salmonella. PMID:33593966
Intraspecific niche partition without speciation: individual level web polymorphism within a single island spider population. PMID:33593195
CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens. PMID:33592498
Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection. PMID:33592092
Genomic and RT-qPCR analysis of trimethoprim-sulfamethoxazole and meropenem resistance in Burkholderia pseudomallei clinical isolates. PMID:33592059
Genomic rearrangements generate hypervariable mini-chromosomes in host-specific isolates of the blast fungus. PMID:33591993
Genetic and epigenetic variation in transposable element expression responses to abiotic stress in maize. PMID:33591319
RADSex: A computational workflow to study sex determination using restriction site-associated DNA sequencing data. PMID:33590960
Twelve years of SAMtools and BCFtools. PMID:33590861
A single system detects and protects the beneficial oral bacterium Streptococcus sp. A12 from a spectrum of antimicrobial peptides. PMID:33590560
Hawk-Seq™ differentiates between various mutations in Salmonella typhimurium TA100 strain caused by exposure to Ames test-positive mutagens. PMID:33590004
Asymmetric introgression reveals the genetic architecture of a plumage trait. PMID:33589637
Microbiome-based environmental monitoring of a dairy processing facility highlights the challenges associated with low microbial-load samples. PMID:33589631
Identification of a long non-coding RNA regulator of liver carcinoma cell survival. PMID:33589614
BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae. PMID:33588990
A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants. PMID:33588989
Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma. PMID:33588787
WACS: improving ChIP-seq peak calling by optimally weighting controls. PMID:33588754
Diversity of dinoflagellate assemblages in coastal temperate and offshore tropical waters of Australia. PMID:33588746
SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans. PMID:33587037
A comprehensive profile of genomic variations in the SARS-CoV-2 isolates from the state of Telangana, India. PMID:33587028
Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers. PMID:33585966
Genozip - A Universal Extensible Genomic Data Compressor. PMID:33585897
Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans. PMID:33585874
Genomic analyses of two Italian oyster mushroom Pleurotus pulmonarius strains. PMID:33585863
Evolutionary analysis and lineage designation of SARS-CoV-2 genomes. PMID:33585048
Improving Nitrogen Use Efficiency Through Overexpression of Alanine Aminotransferase in Rice, Wheat, and Barley. PMID:33584777
Fine Mapping of a Locus Underlying the Ectopic Blade-Like Outgrowths on Leaf and Screening Its Candidate Genes in Rapeseed (Brassica napus L.). PMID:33584757
Comparative Chloroplast Genomics of Corydalis Species (Papaveraceae): Evolutionary Perspectives on Their Unusual Large Scale Rearrangements. PMID:33584746
One-step generation of a targeted knock-in calf using the CRISPR-Cas9 system in bovine zygotes. PMID:33581720
Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions. PMID:33581682
High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq. PMID:33581077
Transcriptional response of Candida albicans to Pseudomonas aeruginosa in a polymicrobial biofilm. PMID:33580263
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms. PMID:33579957
Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling. PMID:33579927
PRMT5 inhibition disrupts splicing and stemness in glioblastoma. PMID:33579912
Transcriptional profiling of fission yeast RNA polymerase II CTD mutants. PMID:33579781
MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations. PMID:33579278
Generation of Chloroplast Molecular Markers to Differentiate Sophora toromiro and Its Hybrids as a First Approach to Its Reintroduction in Rapa Nui (Easter Island). PMID:33578941
Transcriptome Response of Liver and Muscle in Heat-Stressed Laying Hens. PMID:33578825
circTulp4 functions in Alzheimer's disease pathogenesis by regulating its parental gene, Tulp4. PMID:33578037
Duration of SARS-CoV-2 positive in quarantine room environments: A perspective analysis. PMID:33578005
Proteogenomic and metabolomic characterization of human glioblastoma. PMID:33577785
TCP transcription factors suppress cotyledon trichomes by impeding a cell differentiation-regulating complex. PMID:33576799
Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel. PMID:33576176
Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases. PMID:33576154
Improved computational analysis of ribosome dynamics from 5'P degradome data using fivepseq. PMID:33575643
A random forest-based framework for genotyping and accuracy assessment of copy number variations. PMID:33575619
CasCollect: targeted assembly of CRISPR-associated operons from high-throughput sequencing data. PMID:33575613
MinYS: mine your symbiont by targeted genome assembly in symbiotic communities. PMID:33575599
Identification of gene fusion events in Mycobacterium tuberculosis that encode chimeric proteins. PMID:33575588
Critical length in long-read resequencing. PMID:33575574
Targeted exome sequencing for the identification of common mutational signatures and potential driver mutations for brain metastases and prognosis. PMID:33574918
A complex resistance locus in Solanum americanum recognizes a conserved Phytophthora effector. PMID:33574576
Comparative analysis of the transcriptomes of two rice subspecies during domestication. PMID:33574456
S-conLSH: alignment-free gapped mapping of noisy long reads. PMID:33573603
Multi-scale comparative transcriptome analysis reveals key genes and metabolic reprogramming processes associated with oil palm fruit abscission. PMID:33573592
Bioactivity Screening and Gene-Trait Matching across Marine Sponge-Associated Bacteria. PMID:33573261
Comparative Transcriptomic Analysis of Gene Expression Inheritance Patterns Associated with Cabbage Head Heterosis. PMID:33572601
Hybrid seed incompatibility in Capsella is connected to chromatin condensation defects in the endosperm. PMID:33571184
A High-Quality Reference Genome for a Parasitic Bivalve with Doubly Uniparental Inheritance (Bivalvia: Unionida). PMID:33570560
Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease. PMID:33569077
Electric Blue: Molecular Evolution of Three-Finger Toxins in the Long-Glanded Coral Snake Species Calliophis bivirgatus. PMID:33567660
The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers. PMID:33567280
Pathways of calcium regulation, electron transport, and mitochondrial protein translation are molecular signatures of susceptibility to recurrent exertional rhabdomyolysis in Thoroughbred racehorses. PMID:33566847
High-depth resequencing of 312 accessions reveals the local adaptation of foxtail millet. PMID:33566123
Emerging carbapenem-resistant Klebsiella pneumoniae sequence type 16 causing multiple outbreaks in a tertiary hospital in southern Vietnam. PMID:33565955
The branched-chain amino acid aminotransferase TaBCAT1 modulates amino acid metabolism and positively regulates wheat rust susceptibility. PMID:33565586
Is the Dinoflagellate Amoebophrya Really Missing an mtDNA? PMID:33565578
Engineering of primary metabolic pathways for titer improvement of milbemycins in Streptomyces bingchenggensis. PMID:33564920
Donor-derived Cell-free DNA: Advancing a Novel Assay to New Heights in Renal Transplantation. PMID:33564715
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources. PMID:33564056
Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank. PMID:33563995
Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase. PMID:33563994
A genome-wide association study for gut metagenome in Chinese adults illuminates complex diseases. PMID:33563976
Dynamic sex chromosome expression in Drosophila male germ cells. PMID:33563972
Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. PMID:33563832
Plasticity of the Influenza Virus H5 HA Protein. PMID:33563825
Transcriptomic, Protein-DNA Interaction, and Metabolomic Studies of VosA, VelB, and WetA in Aspergillus nidulans Asexual Spores. PMID:33563821
RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs. PMID:33563338
Identification of novel genes involved in neutral lipid storage by quantitative trait loci analysis of Saccharomyces cerevisiae. PMID:33563210
Impact of concurrency on the performance of a whole exome sequencing pipeline. PMID:33563206
Comparative Transcriptomics of Lowland Rice Varieties Uncovers Novel Candidate Genes for Adaptive Iron Excess Tolerance. PMID:33561287
De novo genome assembly of the tobacco hornworm moth (Manduca sexta). PMID:33561252
Genome analysis of Salmonella enterica serovar Typhimurium bacteriophage L, indicator for StySA (StyLT2III) restriction-modification system action. PMID:33561243
Whole-genome sequencing from the New Zealand Saccharomyces cerevisiae population reveals the genomic impacts of novel microbial range expansion. PMID:33561237
A high-quality de novo genome assembly of one swamp eel (Monopterus albus) strain with PacBio and Hi-C sequencing data. PMID:33561235
De novo assembly of a chromosome-scale reference genome for the northern flicker Colaptes auratus. PMID:33561233
A high-quality genome assembly and annotation of the gray mangrove, Avicennia marina. PMID:33561229
Fast and inexpensive whole-genome sequencing library preparation from intact yeast cells. PMID:33561223
Chromosomal assembly of the nuclear genome of the endosymbiont-bearing trypanosomatid Angomonas deanei. PMID:33561222
Comparative transcriptome analyses of the Drosophila pupal eye. PMID:33561221
Carbon fixation and rhodopsin systems in microbial mats from hypersaline lakes Brava and Tebenquiche, Salar de Atacama, Chile. PMID:33561170
Functional Diversification, Redundancy, and Epistasis among Paralogs of the Drosophila melanogaster Obp50a-d Gene Cluster. PMID:33560417
Intronic enhancer region governs transcript-specific Bdnf expression in rodent neurons. PMID:33560226
A first, naturally occurring substitution at the second pyrethroid receptor of voltage-gated sodium channel of Aedes aegypti. PMID:33559956
Contribution of horizontal gene transfer to the functionality of microbial biofilm on a macroalgae. PMID:33558686
Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials. PMID:33558569
Ancient DNA and multimethod dating confirm the late arrival of anatomically modern humans in southern China. PMID:33558418
Conserved IFN Signature between Adult and Pediatric Eosinophilic Esophagitis. PMID:33558373
DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining. PMID:33558311
Investigation of ancestral alleles in the Bovinae subfamily. PMID:33557747
TEfinder: A Bioinformatics Pipeline for Detecting New Transposable Element Insertion Events in Next-Generation Sequencing Data. PMID:33557410
Identifying Wild Versus Cultivated Gene-Alleles Conferring Seed Coat Color and Days to Flowering in Soybean. PMID:33557103
Unraveling the chaotic genomic landscape of primary and metastatic canine appendicular osteosarcoma with current sequencing technologies and bioinformatic approaches. PMID:33556121
A Naturally Heteroplasmic Clam Provides Clues about the Effects of Genetic Bottleneck on Paternal mtDNA. PMID:33555290
Transcription activation depends on the length of the RNA polymerase II C-terminal domain. PMID:33555055
The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID. PMID:33554121
Iron-Deficiency Anemia Results in Transcriptional and Metabolic Remodeling in the Heart Toward a Glycolytic Phenotype. PMID:33553263
High-Resolution Mapping of Transcription Initiation in the Asexual Stages of Toxoplasma gondii. PMID:33553008
Enteric Phageome Alterations in Patients With Type 2 Diabetes. PMID:33552999
Evolutionary Rescue of an Environmental Pseudomonas otitidis in Response to Anthropogenic Perturbation. PMID:33552002
A 44-kb deleted-type copy number variation is associated with decreasing complement component activity and calf mortality in Japanese Black cattle. PMID:33549039
Subgenome evolution in allotetraploid plants. PMID:33547826
Practical prediction model of the clinical response to programmed death-ligand 1 inhibitors in advanced gastric cancer. PMID:33547412
Components of a Neanderthal gut microbiome recovered from fecal sediments from El Salt. PMID:33547403
NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy. PMID:33547395
Genetics of nodulation in Aeschynomene evenia uncovers mechanisms of the rhizobium-legume symbiosis. PMID:33547303
Ph2 encodes the mismatch repair protein MSH7-3D that inhibits wheat homoeologous recombination. PMID:33547285
Reduced proinsecticide activation by cytochrome P450 confers coumaphos resistance in the major bee parasite Varroa destructor. PMID:33547243
Neural divergence and hybrid disruption between ecologically isolated Heliconius butterflies. PMID:33547240
Fixation of allelic gene expression landscapes and expression bias pattern shape the transcriptome of the clonal Amazon molly. PMID:33547183
Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. PMID:33545059
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine. PMID:33544838
Diverging patterns of introgression from Schistosoma bovis across S. haematobium African lineages. PMID:33544762
Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. PMID:33544077
Mating system evolution and genetic structure of diploid sexual populations of Cyrtomium falcatum in Japan. PMID:33542454
Somatic deficiency causes reproductive parasitism in a fungus. PMID:33542245
Whole-genome sequencing data of Kazakh individuals. PMID:33541395
ViR: a tool to solve intrasample variability in the prediction of viral integration sites using whole genome sequencing data. PMID:33541262
Dynamics of a Dual SARS-CoV-2 Lineage Co-Infection on a Prolonged Viral Shedding COVID-19 Case: Insights into Clinical Severity and Disease Duration. PMID:33540596
The piggyBac-derived protein 5 (PGBD5) transposes both the closely and the distantly related piggyBac-like elements Tcr-pble and Ifp2. PMID:33539889
Enhancers predominantly regulate gene expression during differentiation via transcription initiation. PMID:33539786
Multithreaded variant calling in elPrep 5. PMID:33539352
The complete mitochondrial genome of Rhinolophus affinis himalayanus. PMID:33537429
SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing. PMID:33537092
Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival. PMID:33536423
Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway. PMID:33535033
Benchmarking the performance of Pool-seq SNP callers using simulated and real sequencing data. PMID:33534960
Mycoplasma agassizii, an opportunistic pathogen of tortoises, shows very little genetic variation across the Mojave and Sonoran Deserts. PMID:33534823
The Genomes of Two Billfishes Provide Insights into the Evolution of Endothermy in Teleosts. PMID:33533895
Mitochondrial DNA Content Is Linked to Cardiovascular Disease Patient Phenotypes. PMID:33533264
The RNA polymerase II subunit RPB-9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription. PMID:33533030
Haploflow: Strain-resolved de novo assembly of viral genomes. PMID:33532769
Protocol for assaying chromatin accessibility using ATAC-seq in plants. PMID:33532736
Genomic evidence of prevalent hybridization throughout the evolutionary history of the fig-wasp pollination mutualism. PMID:33531484
A Novel Group of Promiscuous Podophages Infecting Diverse Gammaproteobacteria from River Communities Exhibits Dynamic Intergenus Host Adaptation. PMID:33531404
RUNX3 Transcript Variants Have Distinct Roles in Ovarian Carcinoma and Differently Influence Platinum Sensitivity and Angiogenesis. PMID:33530588
Systematic analyses of the MIR172 family members of Arabidopsis define their distinct roles in regulation of APETALA2 during floral transition. PMID:33529186
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts. PMID:33529148
Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae. PMID:33528505
Subcutaneous and intramuscular fat transcriptomes show large differences in network organization and associations with adipose traits in pigs. PMID:33527326
A quantitative genomics map of rice provides genetic insights and guides breeding. PMID:33526925
Microbial production and consumption of hydrocarbons in the global ocean. PMID:33526885
Plant virus evolution under strong drought conditions results in a transition from parasitism to mutualism. PMID:33526695
Epidemic Territorial Spread of IncP-2-Type VIM-2 Carbapenemase-Encoding Megaplasmids in Nosocomial Pseudomonas aeruginosa Populations. PMID:33526490
Mining Grapevine Downy Mildew Susceptibility Genes: A Resource for Genomics-Based Breeding and Tailored Gene Editing. PMID:33525704
MicroRNA Profiles in Monocyte-Derived Macrophages Generated by Interleukin-27 and Human Serum: Identification of a Novel HIV-Inhibiting and Autophagy-Inducing MicroRNA. PMID:33525571
Integrating quantitative proteomics with accurate genome profiling of transcription factors by greenCUT&RUN. PMID:33524153
Human population dynamics and Yersinia pestis in ancient northeast Asia. PMID:33523963
Genetic ancestry changes in Stone to Bronze Age transition in the East European plain. PMID:33523926
EGR1 is a gatekeeper of inflammatory enhancers in human macrophages. PMID:33523892
IsomiR_Window: a system for analyzing small-RNA-seq data in an integrative and user-friendly manner. PMID:33522913
In-host population dynamics of Mycobacterium tuberculosis complex during active disease. PMID:33522489
A new Cannabis genome assembly associates elevated cannabidiol (CBD) with hemp introgressed into marijuana. PMID:33521943
Transcriptional profiling reveals conserved and species-specific plant defense responses during the interaction of Physcomitrium patens with Botrytis cinerea. PMID:33521880
Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity. PMID:33521749
The complete chloroplast genome of Campanula takesimana Nakai from Dokdo Island in Korea (Campanulaceae). PMID:33521286
Complete mitochondrial genome of the gate-keeper ant Colobopsis nipponica (Wheeler, W.M., 1928) (Formicidae: Hymenoptera). PMID:33521277
The complete mitochondrial genome of Aphis gossypii Glover, 1877 (Hemiptera: Aphididae) isolated from Leonurus japonicus in Korea. PMID:33521268
Analysis of Long Non-Coding RNA in Cryptosporidium parvum Reveals Significant Stage-Specific Antisense Transcription. PMID:33520737
Widespread genetic connectivity of feral pigeons across the Northeastern megacity. PMID:33519962
Urbanization is associated with modifications in DNA methylation in a small passerine bird. PMID:33519958
A Density Peak-Based Method to Detect Copy Number Variations From Next-Generation Sequencing Data. PMID:33519925
Hybridization History and Repetitive Element Content in the Genome of a Homoploid Hybrid, Yucca gloriosa (Asparagaceae). PMID:33519836
Variable Release of Lipoteichoic Acid From Staphylococcus aureus Bloodstream Isolates Relates to Distinct Clinical Phenotypes, Strain Background, and Antibiotic Exposure. PMID:33519759
Physiological Tradeoffs of Immune Response Differs by Infection Type in Pieris napi. PMID:33519499
Identifying Signatures of Selection Related to Comb Development. PMID:33519281
Spontaneous Emergence of Azithromycin Resistance in Independent Lineages of Salmonella Typhi in Northern India. PMID:33515460
Revealing nascent RNA processing dynamics with nano-COP. PMID:33514943
Colonization and genetic diversification processes of Leishmania infantum in the Americas. PMID:33514858
Transcriptome analysis reveals the long intergenic noncoding RNAs contributed to skeletal muscle differences between Yorkshire and Tibetan pig. PMID:33514792
De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands. PMID:33514701
A novel canis lupus familiaris reference genome improves variant resolution for use in breed-specific GWAS. PMID:33514656
Genomic variation in the American pika: signatures of geographic isolation and implications for conservation. PMID:33514306
Gene Expression Responses to Sequential Nutrient Deficiency Stresses in Soybean. PMID:33513952
Evolutionary Dynamics of the Pericentromeric Heterochromatin in Drosophila virilis and Related Species. PMID:33513919
Integrating LCM-Based Spatio-Temporal Transcriptomics Uncovers Conceptus and Endometrial Luminal Epithelium Communication that Coordinates the Conceptus Attachment in Pigs. PMID:33513863
The Genetic Architecture of Variation in the Sexually Selected Sword Ornament and Its Evolution in Hybrid Populations. PMID:33513352
Rapid Spread of Mutant Alleles in Worldwide SARS-CoV-2 Strains Revealed by Genome-Wide Single Nucleotide Polymorphism and Variation Analysis. PMID:33512495
ChiRA: an integrated framework for chimeric read analysis from RNA-RNA interactome and RNA structurome data. PMID:33511995
FASTQuick: rapid and comprehensive quality assessment of raw sequence reads. PMID:33511994
Repression of a large number of genes requires interplay between homologous recombination and HIRA. PMID:33511417
A benchmark and an algorithm for detecting germline transposon insertions and measuring de novo transposon insertion frequencies. PMID:33511407
Accessible chromatin regions and their functional interrelations with gene transcription and epigenetic modifications in sorghum genome. PMID:33511349
Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota. PMID:33511258
Inferring historical survivals of climate relicts: the effects of climate changes, geography, and population-specific factors on herbaceous hydrangeas. PMID:33510468
Genome-wide comparative analyses reveal selection signatures underlying adaptation and production in Tibetan and Poll Dorset sheep. PMID:33510350
Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation. PMID:33510161
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems. PMID:33509999
Draft Genome Sequences of Dysgonomonas sp. Strains BGC7 and HGC4, Isolated from the Hindgut of a Lower Termite. PMID:33509995
Genome Sequencing of a Novel Coronavirus SARS-CoV-2 Isolate from Iraq. PMID:33509990
Complete Genome Sequences of 12 Quinolone-Resistant Escherichia coli Strains Containing qnrS1 Based on Hybrid Assemblies. PMID:33509985
[Pregnancy-preserving and maternal-fetal management in a patient with rare large cell neuroendocrine carcinoma of the uterine cervix]. PMID:33509747
PeakMatcher facilitates updated Aedes aegypti embryonic cis-regulatory element map. PMID:33509290
The seasonal changes of the gut microbiome of the population living in traditional lifestyles are represented by characteristic species-level and functional-level SNP enrichment patterns. PMID:33509082
Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data. PMID:33509077
Mitochondrial genome diversity on the Central Siberian Plateau with particular reference to the prehistory of northernmost Eurasia. PMID:33507977
Dysglycemia is associated with Mycobacterium tuberculosis lineages in tuberculosis patients of North Lima-Peru. PMID:33507930
Serial genomic analysis of endometrium supports the existence of histologically indistinct endometrial cancer precursors. PMID:33506979
The rise and fall of the ancient northern pike master sex-determining gene. PMID:33506762
A microbial gene catalog of anaerobic digestion from full-scale biogas plants. PMID:33506264
Genomic diversity of Escherichia coli from healthy children in rural Gambia. PMID:33505796
Population structure of Cydia pomonella granulovirus isolates revealed by quantitative analysis of genetic variation. PMID:33505705
Whole-Exome Sequencing Uncovers Novel Causative Variants and Additional Findings in Three Patients Affected by Glycogen Storage Disease Type VI and Fanconi-Bickel Syndrome. PMID:33505429
Dysregulated H3K27 Acetylation Is Implicated in Fatty Liver Hemorrhagic Syndrome in Chickens. PMID:33505421
CopR, a Global Regulator of Transcription to Maintain Copper Homeostasis in Pyrococcus furiosus. PMID:33505379
Genomic mechanisms of climate adaptation in polyploid bioenergy switchgrass. PMID:33505029
METTL3 regulates heterochromatin in mouse embryonic stem cells. PMID:33505026
Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution. PMID:33504799
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate. PMID:33504790
A circadian clock regulates efflux by the blood-brain barrier in mice and human cells. PMID:33504784
CAGE-seq reveals that HIV-1 latent infection does not trigger unique cellular responses in a Jurkat T cell model. PMID:33504604
Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. PMID:33503434
Sexual and asexual development: two distinct programs producing the same tunicate. PMID:33503429
One is not enough: On the effects of reference genome for the mapping and subsequent analyses of short-reads. PMID:33503026
Identification and sequencing of 59 highly polymorphic microhaplotypes for analysis of DNA mixtures. PMID:33502549
Genomics Reveals the Origins of Historical Specimens. PMID:33502509
A Long-Term Conserved Satellite DNA That Remains Unexpanded in Several Genomes of Characiformes Fish Is Actively Transcribed. PMID:33502491
Pervasive Mitonuclear Coadaptation Underlies Fast Development in Interpopulation Hybrids of a Marine Crustacean. PMID:33502469
Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases. PMID:33502304
Colonization with Staphylococcus aureus and Klebsiella pneumoniae causes infections in a Vietnamese intensive care unit. PMID:33502303
Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rats. PMID:33502259
Transcriptionally active enhancers in human cancer cells. PMID:33502116
Whole-Genome Sequence Data Suggest Environmental Adaptation of Ethiopian Sheep Populations. PMID:33501931
Interferon-regulated genetic programs and JAK/STAT pathway activate the intronic promoter of the short ACE2 isoform in renal proximal tubules. PMID:33501441
Sharing genetic variants with the NGS pipeline is essential for effective genomic data sharing and reproducibility in health information exchange. PMID:33500538
The Compact Macronuclear Genome of the Ciliate Halteria grandinella: A Transcriptome-Like Genome with 23,000 Nanochromosomes. PMID:33500338
Metagenomic analysis suggests broad metabolic potential in extracellular symbionts of the bivalve Thyasira cf. gouldi. PMID:33499960
Occurrence and expression of genes encoding methyl-compound production in rumen bacteria. PMID:33499937
Population genomics reveal rapid genetic differentiation in a recently invasive population of Rattus norvegicus. PMID:33499890
Ancient mitochondrial genomes from Chinese cave hyenas provide insights into the evolutionary history of the genus Crocuta. PMID:33499784
Ancient DNA from the Asiatic Wild Dog (Cuon alpinus) from Europe. PMID:33499169
Genomic Adaption and Mutational Patterns in a HaCaT Subline Resistant to Alkylating Agents and Ionizing Radiation. PMID:33498964
Citrus Tristeza Virus Genotype Detection Using High-Throughput Sequencing. PMID:33498597
A Continuous Statistical Phasing Framework for the Analysis of Forensic Mitochondrial DNA Mixtures. PMID:33498312
Nucleosome landscape reflects phenotypic differences in Trypanosoma cruzi life forms. PMID:33497423
Dbx2 regulation in limbs suggests interTAD sharing of enhancers. PMID:33497014
In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA. PMID:33495639
Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms. PMID:33495598
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis. PMID:33494095
Natural variations of TFIIAγ gene and LOB1 promoter contribute to citrus canker disease resistance in Atalantia buxifolia. PMID:33493197
Whole-genome sequence diversity and association analysis of 198 soybean accessions in mini-core collections. PMID:33492369
The complete mitochondrial genome of Myzus persicae (Sulzer, 1776; Hemiptera: Aphididae) isolated in Korea. PMID:33490586
The complete chloroplast genome of Pterospermum kingtungense, a Critically Endangered species. PMID:33490567
Complete chloroplast genome sequence of Rosa roxburghii and its phylogenetic analysis. PMID:33490491
Genotype and phenotype correlation in a cohort of Chinese congenital hypothyroidism patients with DUOX2 mutations. PMID:33490161
Genome-Wide Histone Modifications and CTCF Enrichment Predict Gene Expression in Sheep Macrophages. PMID:33488675
The hard clam genome reveals massive expansion and diversification of inhibitors of apoptosis in Bivalvia. PMID:33487168
A global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing. PMID:33485316
Chemoreceptor Diversity in Apoid Wasps and Its Reduction during the Evolution of the Pollen-Collecting Lifestyle of Bees (Hymenoptera: Apoidea). PMID:33484563
Identifying the true number of specimens of the extinct blue antelope (Hippotragus leucophaeus). PMID:33483538
Triclosan Tolerance Is Driven by a Conserved Mechanism in Diverse Pseudomonas Species. PMID:33483311
Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer. PMID:33482911
The genetics and physiology of seed dormancy, a crucial trait in common bean domestication. PMID:33482732
Transcription Factors Drive Opposite Relationships between Gene Age and Tissue Specificity in Male and Female Drosophila Gonads. PMID:33481021
An integrated approach to determine the abundance, mutation rate and phylogeny of the SARS-CoV-2 genome. PMID:33479725
Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression. PMID:33479542
Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons. PMID:33479483
Metagenomic analysis of the cow, sheep, reindeer and red deer rumen. PMID:33479378
White pupae phenotype of tephritids is caused by parallel mutations of a MFS transporter. PMID:33479218
Multiple freeze-thaw cycles lead to a loss of consistency in poly(A)-enriched RNA sequencing. PMID:33478392
Identification and Mapping of Tomato Genome Loci Controlling Tolerance and Resistance to Tomato Brown Rugose Fruit Virus. PMID:33478073
Whole-Genome DNA Methylation Analysis in Hydrogen Peroxide Overproducing Transgenic Tobacco Resistant to Biotic and Abiotic Stresses. PMID:33477999
Steroidal Regulation of Oviductal microRNAs Is Associated with microRNA-Processing in Beef Cows. PMID:33477993
Structural Mapping of Mutations in Spike, RdRp and Orf3a Genes of SARS-CoV-2 in Influenza Like Illness (ILI) Patients. PMID:33477951
Systematical Engineering of Synthetic Yeast for Enhanced Production of Lycopene. PMID:33477926
Intra-Host Diversity of SARS-Cov-2 Should Not Be Neglected: Case of the State of Victoria, Australia. PMID:33477885
Analyzing Low-Level mtDNA Heteroplasmy-Pitfalls and Challenges from Bench to Benchmarking. PMID:33477827
Dissecting the Polygenic Basis of Cold Adaptation Using Genome-Wide Association of Traits and Environmental Data in Douglas-fir. PMID:33477542
IFNβ1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment. PMID:33476079
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun. PMID:33475496
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome. PMID:33475257
The complete chloroplast genome of Tetradoxa omeiensis (Adoxaceae) provides insights into the phylogenetic relationship of Adoxaceae. PMID:33474447
The complete chloroplast genome of Antiaris toxicaria, a medicinal and extremely toxic species. PMID:33474432
Characterization of the complete chloroplast genome of Lonicera macranthoides. PMID:33474395
The complete chloroplast genome of Cycas Szechuanensis, an extremely endangered species. PMID:33474385
Characterization of the complete chloroplast genome of Musella lasiocarpa. PMID:33474300
Mitochondrial genomes of the headstanders Megaleporinus muyscorum (Steindachner 1900) and Megaleporinus obtusidens (Valenciennes 1837), (Characiformes, Anostomidae). PMID:33474267
Mitochondrial genomes of the South American electric knifefishes Eigenmannia humboldtii (Steindachner 1878), Eigenmannia limbata (Schreiner and Miranda Ribeiro 1903), Sternopygus aequilabiatus (Humboldt 1805) and Sternopygus macrurus (Bloch and Schneider 1801), (Gymnotiformes, Sternopygidae). PMID:33474246
Species identification and mitochondrial genomes of ancient fish bones from the Riverine Kachemak tradition of the Kenai Peninsula, Alaska. PMID:33474186
The full mitochondrial genomes of Mangalica pig breeds and their possible origin. PMID:33473962
Complete mitochondrial genome of Saiga tatarica (Ruminantia; Pecora; Bovidae) isolate Wuwei in China. PMID:33473945
Complete mitochondrial genome of near threatened butter Catfish Ompok bimaculatus (Siluriformes: Siluridae). PMID:33473811
The complete mitochondrial genome of the Thomas's horseshoe bat (Rhinolophus thomasi) using next-generation sequencing and Sanger sequencing. PMID:33473693
The complete mitochondrial genome of the dusky-footed woodrat(Neotoma fuscipes) (Rodentia, Cricetidae). PMID:33473606
Complete mitochondrial genome of the Sakhalin nine-spined stickleback Pungitius tymensis (Gasterosteiformes, Gasterosteidae). PMID:33473414
Complete mitochondrial genome of the nine-spined stickleback Pungitius pungitius (Gasterosteiformes, Gasterosteidae). PMID:33473413
Complete mitochondrial genome of the Ukrainian nine-spined stickleback Pungitius platygaster (Gasterosteiformes, Gasterosteidae). PMID:33473411
Complete mitochondrial genome of the Greek nine-spined stickleback Pungitius hellenicus (Gasterosteiformes, Gasterosteidae). PMID:33473410
Genomic analysis of GBS data reveals genes associated with facial pigmentation in Xinyang blue-shelled layers. PMID:33473373
Tracking break-induced replication shows that it stalls at roadblocks. PMID:33473214
Reovirus RNA recombination is sequence directed and generates internally deleted defective genome segments during passage. PMID:33472930
Association analysis of repetitive elements and R-loop formation across species. PMID:33472695
Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii. PMID:33472617
Systematic comparison of high-throughput single-cell RNA-seq methods for immune cell profiling. PMID:33472597
Transcriptomic analysis of s-methoprene resistance in the lesser grain borer, Rhyzopertha dominica, and evaluation of piperonyl butoxide as a resistance breaker. PMID:33472593
Target-capture full-length double-strand cDNA sequencing for alternative splicing analysis. PMID:33472537
VELCRO-IP RNA-seq reveals ribosome expansion segment function in translation genome-wide. PMID:33472078
Transcription levels of a noncoding RNA orchestrate opposing regulatory and cell fate outcomes in yeast. PMID:33472063
Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets. PMID:33472060
In silico comparative genomics of SARS-CoV-2 to determine the source and diversity of the pathogen in Bangladesh. PMID:33471859
A novel deletion in FLOWERING LOCUS T modulates flowering time in winter oilseed rape. PMID:33471161
REST promotes ETS1-dependent vascular growth in medulloblastoma. PMID:33469989
SARS-CoV-2 Genomic Variation in Space and Time in Hospitalized Patients in Philadelphia. PMID:33468702
At Least Seven Distinct Rotavirus Genotype Constellations in Bats with Evidence of Reassortment and Zoonotic Transmissions. PMID:33468689
De Novo Cobalamin Biosynthesis, Transport, and Assimilation and Cobalamin-Mediated Regulation of Methionine Biosynthesis in Mycobacterium smegmatis. PMID:33468593
Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. PMID:33468551
Prediction and analysis of metagenomic operons via MetaRon: a pipeline for prediction of Metagenome and whole-genome opeRons. PMID:33468056
Extensive hybridization reveals multiple coloration genes underlying a complex plumage phenotype. PMID:33468000
An 8.22 Mb Assembly and Annotation of the Alpaca (Vicugna pacos) Y Chromosome. PMID:33467186
Real-Time Culture-Independent Microbial Profiling Onboard the International Space Station Using Nanopore Sequencing. PMID:33467183
Metagenome Analysis of a Hydrocarbon-Degrading Bacterial Consortium Reveals the Specific Roles of BTEX Biodegraders. PMID:33466668
Sequencing Red Fox Y Chromosome Fragments to Develop Phylogenetically Informative SNP Markers and Glimpse Male-Specific Trans-Pacific Phylogeography. PMID:33466657
Transportome-wide engineering of Saccharomyces cerevisiae. PMID:33465478
The coronavirus proofreading exoribonuclease mediates extensive viral recombination. PMID:33465137
A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant. PMID:33465109
A novel terpene synthase controls differences in anti-aphrodisiac pheromone production between closely related Heliconius butterflies. PMID:33465061
Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations. PMID:33464204
Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion. PMID:33463551
Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial. PMID:33463067
Predicting sample success for large-scale ancient DNA studies on marine mammals. PMID:33463014
NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex. PMID:33462516
inStrain profiles population microdiversity from metagenomic data and sensitively detects shared microbial strains. PMID:33462508
The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer. PMID:33462444
The impact of genetic diversity on gene essentiality within the Escherichia coli species. PMID:33462433
Phytoplankton consortia as a blueprint for mutually beneficial eukaryote-bacteria ecosystems based on the biocoenosis of Botryococcus consortia. PMID:33462312
Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis. PMID:33462242
DNA methylome signatures of prenatal exposure to synthetic glucocorticoids in hippocampus and peripheral whole blood of female guinea pigs in early life. PMID:33462183
Freshwater monitoring by nanopore sequencing. PMID:33461660
Expression quantitative trait loci in sheep liver and muscle contribute to variations in meat traits. PMID:33461502
MSIsensor-ct: microsatellite instability detection using cfDNA sequencing data. PMID:33461213
Regulatory roles of Escherichia coli 5' UTR and ORF-internal RNAs detected by 3' end mapping. PMID:33460557
The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif. PMID:33460454
Next-generation sequencing yields complete mitochondrial genome assembly of peaceful betta fish, Betta imbellis (Teleostei: Osphronemidae). PMID:33458245
The complete mitochondrial genome of new species candidate of Rosa rugosa (Rosaceae). PMID:33458196
The complete mitochondrial genome of Wiesnerella denudata (Mitt.) Steph. (Wiesnerellaceae, Marchantiophyta): large number of intraspecific variations on mitochondrial genomes of W. denudata. PMID:33458166
The complete chloroplast genome of Wiesnerella denudata (Mitt.) Steph. (Wiesnerellaceae, Marchantiophyta). PMID:33458082
Complete mitochondrial genome of Mahachai betta, Betta mahachaiensis (Teleostei: Osphronemidae). PMID:33458058
The second complete mitochondrial genome of Alphitobius diaperinus Panzer, 1797 (Coleoptera: Tenebrionidae): investigation of intraspecific variations on mitochondrial genome. PMID:33458023
The complete chloroplast genome of Scapania ampliata Steph., 1897 (Scapaniaceae, Jungermanniales). PMID:33457990
The complete mitochondrial genome of Aphis gossypii Glover, 1877 (Hemiptera: Aphididae) isolated from Plantago asiatica in Korea. PMID:33457986
The complete mitochondrial genome of Cervus canadensis (Erxleben, 1777), as a model species of Chronic Wasting Disease (CWD). PMID:33457884
The first complete mitogenome of Cervus canadensis nannodes (Merriam, 1905). PMID:33457766
Risk prediction and marker selection in nonsynonymous single nucleotide polymorphisms using whole genome sequencing data. PMID:33456716
Lipin 1 deficiency causes adult-onset myasthenia with motor neuron dysfunction in humans and neuromuscular junction defects in zebrafish. PMID:33456573
Unidirectional movement of small RNAs from shoots to roots in interspecific heterografts. PMID:33452489
Glycine max NNL1 restricts symbiotic compatibility with widely distributed bradyrhizobia via root hair infection. PMID:33452487
Newly discovered Asgard archaea Hermodarchaeota potentially degrade alkanes and aromatics via alkyl/benzyl-succinate synthase and benzoyl-CoA pathway. PMID:33452484
Bodo saltans (Kinetoplastida) is dependent on a novel Paracaedibacter-like endosymbiont that possesses multiple putative toxin-antitoxin systems. PMID:33452479
EBF1 drives hallmark B cell gene expression by enabling the interaction of PAX5 with the MLL H3K4 methyltransferase complex. PMID:33452395
Sequencing of the Arabidopsis NOR2 reveals its distinct organization and tissue-specific rRNA ribosomal variants. PMID:33452254
Radiation-induced toxicity in rectal epithelial stem cell contributes to acute radiation injury in rectum. PMID:33451351
Parasite Presence Induces Gene Expression Changes in an Ant Host Related to Immunity and Longevity. PMID:33451085
Contribution of Mitochondrial DNA Heteroplasmy to the Congenital Cardiac and Palatal Phenotypic Variability in Maternally Transmitted 22q11.2 Deletion Syndrome. PMID:33450921
The C-terminal Domain of piggyBac Transposase Is Not Required for DNA Transposition. PMID:33450253
Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. PMID:33450205
Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells. PMID:33450185
The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes. PMID:33450001
Rad18 mediates specific mutational signatures and shapes the genomic landscape of carcinogen-induced tumors in vivo. PMID:33447826
Genetic determinants of Pseudomonas aeruginosa fitness during biofilm growth. PMID:33447809
Whole-exome sequencing identifies susceptibility genes and pathways for idiopathic pulmonary fibrosis in the Chinese population. PMID:33446833
An in vivo screen of noncoding loci reveals that Daedalus is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis. PMID:33446502
Reduced RNA turnover as a driver of cellular senescence. PMID:33446491
SPIN reveals genome-wide landscape of nuclear compartmentalization. PMID:33446254
High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts. PMID:33446241
A toolkit for studying Varroa genomics and transcriptomics: preservation, extraction, and sequencing library preparation. PMID:33446105
Genetic variation for tolerance to the downy mildew pathogen Peronospora variabilis in genetic resources of quinoa (Chenopodium quinoa). PMID:33446098
Genotype-by-Sequencing Analysis of Mutations and Recombination in Pepper Progeny of Gamma-Irradiated Gametophytes. PMID:33445585
Whole Genome Sequencing Reveals the Effects of Recent Artificial Selection on Litter Size of Bamei Mutton Sheep. PMID:33445473
CLK-2/TEL2 is a conserved component of the nonsense-mediated mRNA decay pathway. PMID:33444416
Genomic Steppe ancestry in skeletons from the Neolithic Single Grave Culture in Denmark. PMID:33444387
Genome sequence analysis provides insights on genomic variation and late blight resistance genes in potato somatic hybrid (parents and progeny). PMID:33442830
Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian cells. PMID:33442052
Transcriptome-wide high-throughput mapping of protein-RNA occupancy profiles using POP-seq. PMID:33441968
Mitochondrial haplogroup J associated with higher risk of obesity in the Qatari population. PMID:33441698
Genomic signatures of the evolution of defence against its natural enemies in the poisonous and medicinal plant Datura stramonium (Solanaceae). PMID:33441607
Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life. PMID:33441584
Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection. PMID:33441574
TNF-α Regulates Human Plasmacytoid Dendritic Cells by Suppressing IFN-α Production and Enhancing T Cell Activation. PMID:33441439
Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease. PMID:33441415
Randomized Controlled Trial of Oral Vancomycin Treatment in Clostridioides difficile-Colonized Patients. PMID:33441409
The variant call format provides efficient and robust storage of GWAS summary statistics. PMID:33441155
The Acquisition of Colistin Resistance Is Associated to the Amplification of a Large Chromosomal Region in Klebsiella pneumoniae kp52145. PMID:33440735
Co-transcriptional splicing regulates 3' end cleavage during mammalian erythropoiesis. PMID:33440169
Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures. PMID:33439897
Quantitative analysis of the splice variants expressed by the major hepatitis B virus genotypes. PMID:33439114
A Reference Genome Assembly of Simmental Cattle, Bos taurus taurus. PMID:33438035
Markers for genetic change. PMID:33437884
Tracing species replacement in Iberian marbled newts. PMID:33437438
Phylogeny and biogeography of the Japanese rhinoceros beetle, Trypoxylus dichotomus (Coleoptera: Scarabaeidae) based on SNP markers. PMID:33437420
Gene expression and functional abnormalities in XX/Sry Leydig cells. PMID:33436964
Multi-level remodelling of chromatin underlying activation of human T cells. PMID:33436846
Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts. PMID:33436758
Human whole genome sequencing in South Africa. PMID:33436733
Quantitative trait loci and transcriptome signatures associated with avian heritable resistance to Campylobacter. PMID:33436657
H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots. PMID:33436613
SCISSOR: a framework for identifying structural changes in RNA transcripts. PMID:33436599
Dinoroseobacter shibae Outer Membrane Vesicles Are Enriched for the Chromosome Dimer Resolution Site dif. PMID:33436507
Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop. PMID:33436428
Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers. PMID:33435622
The Cxxc1 subunit of the Trithorax complex directs epigenetic licensing of CD4+ T cell differentiation. PMID:33433611
First Complete Genome of the Thermophilic Polyhydroxyalkanoates-Producing Bacterium Schlegelella thermodepolymerans DSM 15344. PMID:33432323
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. PMID:33432195
Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes. PMID:33432154
Short prolactin isoforms are expressed in photoreceptors of canine retinas undergoing retinal degeneration. PMID:33432105
Discovery of SNPs and InDels in papaya genotypes and its potential for marker assisted selection of fruit quality traits. PMID:33431939
Two novel venom proteins underlie divergent parasitic strategies between a generalist and a specialist parasite. PMID:33431897
Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference. PMID:33431880
BET inhibition disrupts transcription but retains enhancer-promoter contact. PMID:33431820
Ultraviolet radiation drives mutations in a subset of mucosal melanomas. PMID:33431815
Measurable genomic changes in Mycobacterium avium subsp. hominissuis after long-term adaptation in Acanthamoeba lenticulata and reduced persistence in macrophages. PMID:33431432
Global histone protein surface accessibility in yeast indicates a uniformly loosely packed genome with canonical nucleosomes. PMID:33430969
Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care. PMID:33430949
Resequencing of global Tartary buckwheat accessions reveals multiple domestication events and key loci associated with agronomic traits. PMID:33430931
Transcriptomic Profiling of Equine and Viral Genes in Peripheral Blood Mononuclear Cells in Horses during Equine Herpesvirus 1 Infection. PMID:33430330
Escalation in the host-pathogen arms race: A host resistance response corresponds to a heightened bacterial virulence response. PMID:33428681
Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes from a dataset of 3,552 Japanese whole genomes (3.5KJPNv2). PMID:33428613
Selfing is the safest sex for Caenorhabditis tropicalis. PMID:33427200
The complete mitochondrial genome of the millipede Epanerchodus koreanus Verhoeff, 1937 collected in limestone cave of Korea (Polydesmidae: Polydesmida). PMID:33426298
The complete mitochondrial genome of Ricania shantungensis (Hemiptera: Ricaniidae) in Korea. PMID:33426286
The complete mitochondrial genome of Nylanderia flavipes (Smith, 1874) (Hymenoptera: Formicidae). PMID:33426274
Genetic Variation, GWAS and Accuracy of Prediction for Host Resistance to Sparicotyle chrysophrii in Farmed Gilthead Sea Bream (Sparus aurata). PMID:33424925
Genomic Analyses Reveal Adaptation to Hot Arid and Harsh Environments in Native Chickens of China. PMID:33424922
Dinoflagellate Host Chloroplasts and Mitochondria Remain Functional During Amoebophrya Infection. PMID:33424803
Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirus. PMID:33423067
Induced defense response in red mango fruit against Colletotrichum gloeosporioides. PMID:33423039
TCF7L2 silencing results in altered gene expression patterns accompanied by local genomic reorganization. PMID:33422939
Unexpectedly Low Natriuretic Peptide Levels in Patients With Heart Failure. PMID:33422435
Re-purposing software for functional characterization of the microbiome. PMID:33422152
Environmental RNAi pathways in the two-spotted spider mite. PMID:33421998
First genome sequencing of SARS-CoV-2 recovered from an infected cat and its owner in Latin America. PMID:33421326
Genome-wide variation in DNA methylation linked to developmental stage and chromosomal suppression of recombination in white-throated sparrows. PMID:33421223
The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors. PMID:33420489
Comprehensive characterisation of intronic mis-splicing mutations in human cancers. PMID:33420369
Functional Common and Rare ERBB2 Germline Variants Cooperate in Familial and Sporadic Cancer Susceptibility. PMID:33419763
Ratatosk: hybrid error correction of long reads enables accurate variant calling and assembly. PMID:33419473
Characterization of metabolic responses, genetic variations, and microsatellite instability in ammonia-stressed CHO cells grown in fed-batch cultures. PMID:33419422
Tight association of genome rearrangements with gene expression in conifer plastomes. PMID:33419387
Multi-Omics Approach Reveals miR-SNPs Affecting Muscle Fatty Acids Profile in Nelore Cattle. PMID:33419037
Different Gene Networks Are Disturbed by Zika Virus Infection in A Mouse Microcephaly Model. PMID:33418086
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma. PMID:33417831
The genome of walking catfish Clarias magur (Hamilton, 1822) unveils the genetic basis that may have facilitated the development of environmental and terrestrial adaptation systems in air-breathing catfishes. PMID:33416875
BamSnap: a lightweight viewer for sequencing reads in BAM files. PMID:33416869
A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes. PMID:33416493
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. PMID:33414553
Genomic Sequences and Analysis of Five SARS-CoV-2 Variants Obtained from Patients in Lambayeque, Peru. PMID:33414350
Mutation Profile of SARS-CoV-2 Genome Sequences Originating from Eight Israeli Patient Isolates. PMID:33414330
Genome Sequences of Two GH Clade SARS-CoV-2 Strains Isolated from Patients with COVID-19 in South Korea. PMID:33414329
Complete Genome Sequences of Three Listeria monocytogenes Bacteriophage Propagation Strains. PMID:33414304
Complete Genome Sequence of a Serotype 7 Listeria monocytogenes Strain, FSL R9-0915. PMID:33414303
Complete Genome Sequences of Four Atrazine-Degrading Bacterial Strains, Pseudomonas sp. Strain ADPe, Arthrobacter sp. Strain TES, Variovorax sp. Strain 38R, and Chelatobacter sp. Strain SR38. PMID:33414292
Transcriptomic time-series analysis of cold- and heat-shock response in psychrotrophic lactic acid bacteria. PMID:33413101
Nutrient-imbalanced conditions shift the interplay between zooplankton and gut microbiota. PMID:33413098
A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies. PMID:33412588
Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy. PMID:33411788
Microbial Species that Initially Colonize the Human Gut at Birth or in Early Childhood Can Stay in Human Body for Lifetime. PMID:33410935
PM4NGS, a project management framework for next-generation sequencing data analysis. PMID:33410471
Chromosome-level reference genome of the European wasp spider Argiope bruennichi: a resource for studies on range expansion and evolutionary adaptation. PMID:33410470
Single enzyme RT-PCR of full-length ribosomal RNA. PMID:33409375
Novel NGS pipeline for virus discovery from a wide spectrum of hosts and sample types. PMID:33408878
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation. PMID:33408774
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice. PMID:33408413
St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem. PMID:33408242
The Majority of Typhoid Toxin-Positive Salmonella Serovars Encode ArtB, an Alternate Binding Subunit. PMID:33408236
Genomic Epidemiology and Evolution of Escherichia coli in Wild Animals in Mexico. PMID:33408222
Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood. PMID:33407823
Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences. PMID:33407744
Targeted amplicon sequencing + next-generation sequencing-based bulked segregant analysis identified genetic loci associated with preharvest sprouting tolerance in common buckwheat (Fagopyrum esculentum). PMID:33407135
Physical mapping and InDel marker development for the restorer gene Rf2 in cytoplasmic male sterile CMS-D8 cotton. PMID:33407111
Genome-wide association analysis reveals genetic variations and candidate genes associated with salt tolerance related traits in Gossypium hirsutum. PMID:33407102
ATAC-Seq identifies regions of open chromatin in the bronchial lymph nodes of dairy calves experimentally challenged with bovine respiratory syncytial virus. PMID:33407093
Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression. PMID:33406418
A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks. PMID:33406239
Gene-specific mutagenesis enables rapid continuous evolution of enzymes in vivo. PMID:33406230
Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts. PMID:33406151
Patterns of relatedness and genetic diversity inferred from whole genome sequencing of archival blood fluke miracidia (Schistosoma japonicum). PMID:33406094
Single-nucleotide polymorphisms responsible for pseudo-albinism and hypermelanosis in Japanese flounder (Paralichthys olivaceus) and reveal two genes related to malpigmentation. PMID:33405062
The UVSSA complex alleviates MYC-driven transcription stress. PMID:33404608
Identification and initial characterization of POLIII-driven transcripts by msRNA-sequencing. PMID:33404286
A chromatin-associated splicing isoform of OIP5-AS1 acts in cis to regulate the OIP5 oncogene. PMID:33404283
Tool recommender system in Galaxy using deep learning. PMID:33404053
Signature changes in the expressions of protein-coding genes, lncRNAs, and repeat elements in early and late cellular senescence. PMID:33402863
Putative second hit rare genetic variants in families with seemingly GBA-associated Parkinson's disease. PMID:33402667
Crosstalk between codon optimality and cis-regulatory elements dictates mRNA stability. PMID:33402205
Equivalent DNA methylation variation between monozygotic co-twins and unrelated individuals reveals universal epigenetic inter-individual dissimilarity. PMID:33402197
The landscape of lncRNAs in Cydia pomonella provides insights into their signatures and potential roles in transcriptional regulation. PMID:33402093
Temperature modulates immune gene expression in mosquitoes during arbovirus infection. PMID:33401993
Hyperosmotic stress alters the RNA polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression. PMID:33400923
European context of the diversity and phylogenetic position of SARS-CoV-2 sequences from Polish COVID-19 patients. PMID:33400131
Accurate, scalable cohort variant calls using DeepVariant and GLnexus. PMID:33399819
Paternal age affects offspring via an epigenetic mechanism involving REST/NRSF. PMID:33399271
Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection. PMID:33398179
Improved metagenome binning and assembly using deep variational autoencoders. PMID:33398153
Rate volatility and asymmetric segregation diversify mutation burden in cells with mutator alleles. PMID:33398111
Temperature modulates stress response in mainstream anammox reactors. PMID:33398049
Genomic alterations caused by HPV integration in a cohort of Chinese endocervical adenocarcinomas. PMID:33398034
Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes. PMID:33397987
The patterns of deleterious mutations during the domestication of soybean. PMID:33397978
ZNF143 mediates CTCF-bound promoter-enhancer loops required for murine hematopoietic stem and progenitor cell function. PMID:33397967
Rapid parallel adaptation despite gene flow in silent crickets. PMID:33397914
Harnessing CRISPR-Cas9 for Genome Editing in Streptococcus pneumoniae D39V. PMID:33397704
Targeted Mutagenesis of the Female-Suppressor SyGI Gene in Tetraploid Kiwifruit by CRISPR/CAS9. PMID:33396671
CRISPR/Cas9 Induced Somatic Recombination at the CRTISO Locus in Tomato. PMID:33396568
Characterization of bacteriophage T7-Ah reveals its lytic activity against a subset of both mesophilic and psychrophilic Aeromonas salmonicida strains. PMID:33394168
Epigenome-wide association study (EWAS) for potential transgenerational disease epigenetic biomarkers in sperm following ancestral exposure to the pesticide methoxychlor. PMID:33391823
FastD: Fast detection of insecticide target-site mutations and overexpressed detoxification genes in insect populations from RNA-Seq data. PMID:33391720
Evolutionary history of endangered and relict tree species Dipteronia sinensis in response to geological and climatic events in the Qinling Mountains and adjacent areas. PMID:33391701
Whole-exome Sequencing of Prostate Cancer in Sardinian Identify Recurrent UDP-glucuronosyltransferase Amplifications. PMID:33391440
Specific MiRNAs in naïve T cells associated with Hepatitis C Virus-induced Hepatocellular Carcinoma. PMID:33391397
Mutation Frequency in Main Susceptibility Genes Among Patients With Head and Neck Paragangliomas. PMID:33391357
Genetic Mapping of Climbing and Mimicry: Two Behavioral Traits Degraded During Silkworm Domestication. PMID:33391338
So Closely Related and Yet So Different: Strong Contrasts Between the Evolutionary Histories of Species of the Cardamine pratensis Polyploid Complex in Central Europe. PMID:33391302
Genome-to-phenome research in rats: progress and perspectives. PMID:33390838
Minimal prezygotic isolation between ecologically divergent sibling species. PMID:33390615
A combined BSA-Seq and linkage mapping approach identifies genomic regions associated with Phytophthora root and crown rot resistance in squash. PMID:33388885
RNA-Seq used to identify ipsdienone reductase (IDONER): A novel monoterpene carbon-carbon double bond reductase central to Ips confusus pheromone production. PMID:33388375
Dynamics of severe acute respiratory syndrome coronavirus 2 genome variants in the feces during convalescence. PMID:33388272
De novo ZIC2 frameshift variant associated with frontonasal dysplasia in a Limousin calf. PMID:33388042
Variation in Pleiotropic Hub Gene Expression Is Associated with Interspecific Differences in Head Shape and Eye Size in Drosophila. PMID:33386848
Demographic History and Genomic Response to Environmental Changes in a Rapid Radiation of Wild Rats. PMID:33386846
QTL controlling fiber quality traits under salt stress in upland cotton (Gossypium hirsutum L.). PMID:33386428
Genetic Diversity, Inbreeding Level, and Genetic Load in Endangered Snub-Nosed Monkeys (Rhinopithecus). PMID:33384722
Genome and transcriptome of Papaver somniferum Chinese landrace CHM indicates that massive genome expansion contributes to high benzylisoquinoline alkaloid biosynthesis. PMID:33384435
Insight into the bZIP Gene Family in Solanum tuberosum: Genome and Transcriptome Analysis to Understand the Roles of Gene Diversification in Spatiotemporal Gene Expression and Function. PMID:33383823
Soft Selective Sweep on Chemosensory Genes Correlates with Ancestral Preference for Toxic Noni in a Specialist Drosophila Population. PMID:33383708
The cancer microbiome atlas: a pan-cancer comparative analysis to distinguish tissue-resident microbiota from contaminants. PMID:33382980
Whole-genome sequence analysis and comparisons between drug-resistance mutations and minimum inhibitory concentrations of Mycobacterium tuberculosis isolates causing M/XDR-TB. PMID:33382836
A Targeted Gene Panel for Circulating Tumor DNA Sequencing in Neuroblastoma. PMID:33381456
Chloroplast Electron Chain, ROS Production, and Redox Homeostasis Are Modulated by COS-OGA Elicitation in Tomato (Solanum lycopersicum) Leaves. PMID:33381134
Botrytis cinerea Transcriptome during the Infection Process of the Bryophyte Physcomitrium patens and Angiosperms. PMID:33379257
NGS-PrimerPlex: High-throughput primer design for multiplex polymerase chain reactions. PMID:33378360
Multi-Approach Analysis Reveals Local Adaptation in a Widespread Forest Tree of Reunion Island. PMID:33377945
Circulating tumor cell characterization of lung cancer brain metastases in the cerebrospinal fluid through single-cell transcriptome analysis. PMID:33377642
Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons. PMID:33377122
Protocol for High-Throughput Analysis of Sister-Chromatids Contacts. PMID:33377096
Genome-wide Interrogation of Protein-DNA Interactions in Mammalian Cells Using ChIPmentation. PMID:33377081
TARGET-Seq: A Protocol for High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing. PMID:33377019
meCLICK-Seq, a Substrate-Hijacking and RNA Degradation Strategy for the Study of RNA Methylation. PMID:33376781
Characterization of the genomic sequence data around common cutworm resistance genes in soybean (Glycine max) using short- and long-read sequencing methods. PMID:33376760
Identification of m6A residues at single-nucleotide resolution using eCLIP and an accessible custom analysis pipeline. PMID:33376190
Genomic Insight into Pediococcus acidilactici HN9, a Potential Probiotic Strain Isolated from the Traditional Thai-Style Fermented Beef Nhang. PMID:33375492
On genetic diversity in caraway: Genotyping of a large germplasm collection. PMID:33373410
Gamete binning: chromosome-level and haplotype-resolved genome assembly enabled by high-throughput single-cell sequencing of gamete genomes. PMID:33372615
intePareto: an R package for integrative analyses of RNA-Seq and ChIP-Seq data. PMID:33372591
Wheat heat tolerance is impaired by heightened deletions in the distal end of 4AL chromosomal arm. PMID:33372381
3D landscape of Hepatitis B virus interactions with human chromatins. PMID:33372176
LDscaff: LD-based scaffolding of de novo genome assemblies. PMID:33371875
Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment. PMID:33371412
Increased virulence of Puccinia coronata f. sp.avenae populations through allele frequency changes at multiple putative Avr loci. PMID:33370783
The latency-associated transcript locus of herpes simplex virus 1 is a virulence determinant in human skin. PMID:33370402
Molecular signatures of sexual communication in the phlebotomine sand flies. PMID:33370303
A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover. PMID:33370288
The PfAP2-G2 transcription factor is a critical regulator of gametocyte maturation. PMID:33368818
GeneBreaker: Variant simulation to improve the diagnosis of Mendelian rare genetic diseases. PMID:33368787
Chromatin structure restricts origin utilization when quiescent cells re-enter the cell cycle. PMID:33367871
HAPHPIPE: Haplotype Reconstruction and Phylodynamics for Deep Sequencing of Intrahost Viral Populations. PMID:33367849
Determinants of adenine-mutagenesis in diversity-generating retroelements. PMID:33367793
Legionella antimicrobial sensitivity testing: comparison of microbroth dilution with BCYE and LASARUS solid media. PMID:33367732
Demographic Processes Linked to Genetic Diversity and Positive Selection across a Species' Range. PMID:33367266
Variation Patterns of NLR Clusters in Arabidopsis thaliana Genomes. PMID:33367252
Highly Pathogenic Avian Influenza H5N8 in Poland in 2019-2020. PMID:33367134
The complete mitochondrial genome of Ricania speculum (Walker, 1851) (Hemiptera: Ricaniidae): investigation of intraspecific variations on mitochondrial genome. PMID:33367111
The complete plastome of Nannoglottis ravida, an extremely endangered species in the Qinghai-Tibet Plateau. PMID:33367078
The complete chloroplast genome of Douinia plicata (Lindb.) Konstant. & Vilnet (Scapaniaceae, Jungermanniales). PMID:33367065
Complete chloroplast genome sequence of an alpine rhubarb Rheum likiangense. PMID:33367058
Complete mitochondrial genome sequence of Afla-Guard®, commercially available non-toxigenic Aspergillus flavus. PMID:33367022
Complete mitochondrial genome sequence of Aspergillus flavus SRRC1009: insight of intraspecific variations on A. flavus mitochondrial genomes. PMID:33367020
The complete mitochondrial genome of Alphitobius diaperinus Panzer, 1797 (Coleoptera: Tenebrionidae). PMID:33367012
The complete chloroplast genome of Agrimonia pilosa Ledeb. isolated in Korea (Rosaceae): investigation of intraspecific variations on its chloroplast genomes. PMID:33367001
The complete mitochondrial genome of Riccia fluitans L. (Ricciaceae, Marchantiophyta): investigation of intraspecific variations on mitochondrial genomes of R. fluitans. PMID:33366919
The complete mitochondrial genome of Batrachuperus sp. 2 (Caudata: Hynobiidae). PMID:33366878
The complete mitochondrial genome of an enigmatic predaceous springtail Metisotoma macnamarai from northeast China. PMID:33366623
The complete mitochondrial genome of Aphaenogaster famelica (Smith, 1874) (Hymenoptera: Formicidae). PMID:33366617
The complete mitochondrial genome of Rotunda rotundapex (Miyata & Kishida, 1990) (Lepidoptera: Bombycidae). PMID:33366554
The complete mitochondrial genome of Ochetellus glaber (Mayr, 1862) (Hymenoptera:Formicidae). PMID:33366461
The complete mitochondrial genome of the fall armyworm, Spodoptera frugiperda Smith, 1797 (Lepidoptera; Noctuidae), firstly collected in Korea. PMID:33366251
The complete chloroplast genome of Camellia vietnamensis, an economic shrub producing edible seed oil. PMID:33366166
The complete chloroplast genome of a new candidate cultivar, Sang Jae, of Abeliophyllum distichum Nakai (Oleaceae): initial step of A. distichum intraspecies variations atlas. PMID:33366157
The complete chloroplast genome of a new candidate cultivar, Dae Ryun, of Abeliophyllum distichum Nakai (Oleaceae). PMID:33366156
Complete mitochondrial genome sequence of lettuce pathogenic fungus, Fusarium oxysporum f. sp. lactucae 09-002. PMID:33366027
The complete chloroplast genome of Aconitum coreanum (H. Lév.) Rapaics (Ranunculaceae). PMID:33366014
The complete chloroplast genome sequence of Viburnum erosum (Adoxaceae). PMID:33365955
Complete mitochondrial genome sequence of lettuce pathogenic fungus, Fusarium oxysporum f. sp. lactucae 16-086. PMID:33365930
The complete mitochondrial genome of Ceutorhynchus obstrictus (Marsham, 1802) (Coleoptera: Curculionidae). PMID:33365869
The complete mitochondrial genome of Paracolopha morrisoni (Baker, 1919) (Hemiptera: Aphididae). PMID:33365845
The complete mitochondrial genome of Aphis gossypii Glover, 1877 (Hemiptera: Aphididae) collected in Korean peninsula. PMID:33365831
The complete chloroplast genome of agarwood producing species, Aquilaria sinensis (Lour.) Gilg: a species on IUCN red list. PMID:33365825
The complete chloroplast genome of Leucobryum juniperoideum (brid.) C. Müll. (Leucobryaceae, Bryophyta). PMID:33365811
The complete chloroplast genome sequence of Goodyera schlechtendaliana in Korea (Orchidaceae). PMID:33365686
The complete chloroplast genome of tulip tree, Liriodendron tulifipera L. (Magnoliaceae): investigation of intra-species chloroplast variations. PMID:33365610
The complete chloroplast and mitochondrial genomes of Hyunsasi tree, Populus alba x Populus glandulosa (Salicaceae). PMID:33365609
The complete chloroplast genome of coffee tree, Coffea arabica L. 'Blue Mountain' (Rubiaceae). PMID:33365575
The complete chloroplast genome of candidate new species from Rosa rugosa in Korea (Rosaceae). PMID:33365574
The complete chloroplast genome of Korean Pyrus ussuriensis Maxim. (Rosaceae): providing genetic background of two types of P. ussuriensis. PMID:33365570
Complete mitochondrial genome sequence of a xerophilic fungus, Aspergillus pseudoglaucus. PMID:33365569
The complete chloroplast genome of Potentilla Freyniana Bornm. (Rosaceae). PMID:33365568
The complete chloroplast genome of Korean endemic species, Cirsium rhinoceros (H.Lév. & vaniot) Nakai (Asteraceae). PMID:33365539
The complete mitochondrial genome of Neocaridina heteropoda koreana Kubo, 1938 (Decapoda: Atyidae). PMID:33365530
The complete chloroplast genome of Prince Ginseng, Pseudostellaria heterophylla (Miq.) Pax (Caryophyllaceae). PMID:33365497
The complete mitochondrial genome of Exorista japonica (Townsend, 1909) (Diptera:Tachinidae). PMID:33365494
The complete mitochondrial genome of Laodelphax striatellus (Fallén, 1826) (Hemiptera: Delphacidae) collected in a southern part of Korean peninsula. PMID:33365493
The complete chloroplast genome of coffee tree, Coffea arabica L. 'Typica' (Rubiaceae). PMID:33365492
The complete mitochondrial genome of Laodelphax striatellus (Fallén, 1826) (Hemiptera: Delphacidae) collected in a mid-Western part of Korean peninsula. PMID:33365487
The complete chloroplast genome of Fissidens nobilis Griff. (Fissidentaceae, Bryophyta). PMID:33365485
The complete chloroplast genome of Gentaina urnula (Gentianaceae). PMID:33365448
The complete chloroplast genome sequence of rose-gold pussy willow, Salix gracilistyla Miq. (Salicaceae). PMID:33365434
Distinctive Cellular and Metabolic Reprogramming in Porcine Lung Mononuclear Phagocytes Infected With Type 1 PRRSV Strains. PMID:33365028
Physiological Effects of Water Flow Induced Swimming Exercise in Seabream Sparus aurata. PMID:33364981
Epigenetic Variation Analysis Leads to Biomarker Discovery in Gastric Adenocarcinoma. PMID:33363566
Genetic and Clinical Profiles of Pheochromocytoma and Paraganglioma: A Single Center Study. PMID:33362715
Novel CRISPR-based sequence specific enrichment methods for target loci and single base mutations. PMID:33362267
Polymorphisms in mitochondrial ribosomal protein S5 (MRPS5) are associated with leprosy risk in Chinese. PMID:33362202
A genetic history of the pre-contact Caribbean. PMID:33361817
DEFECTIVE ENDOSPERM-D1 (Dee-D1) is crucial for endosperm development in hexaploid wheat. PMID:33361776
Traditional Human Populations and Nonhuman Primates Show Parallel Gut Microbiome Adaptations to Analogous Ecological Conditions. PMID:33361321
In Vitro Selection Implicates ROP1 as a Resistance Gene for an Experimental Therapeutic Benzoquinone Acyl Hydrazone in Toxoplasma gondii. PMID:33361291
Identification of a Chromosomal Integrated DNA Fragment Containing the rmpA2 and iucABCDiutA Virulence Genes in Klebsiella pneumoniae. PMID:33361128
SARS-CoV-2 RNA monitoring in wastewater as a potential early warning system for COVID-19 transmission in the community: A temporal case study. PMID:33360129
Discovery of cellular substrates of human RNA-decapping enzyme DCP2 using a stapled bicyclic peptide inhibitor. PMID:33357462
CLIP and Massively Parallel Functional Analysis of CELF6 Reveal a Role in Destabilizing Synaptic Gene mRNAs through Interaction with 3' UTR Elements. PMID:33357440
RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions. PMID:33357438
CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci. PMID:33357429
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1. PMID:33357424
Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest. PMID:33357381
Tissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency. PMID:33356838
Phase 1 study of belinostat (PXD-101) and bortezomib (Velcade, PS-341) in patients with relapsed or refractory acute leukemia and myelodysplastic syndrome. PMID:33356689
A cis-regulatory change underlying the motor neuron-specific loss of Ebf expression in immotile tunicate larvae. PMID:33355999
Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development. PMID:33355311
DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution. PMID:33355294
Recalibration of mapping quality scores in Illumina short-read alignments improves SNP detection results in low-coverage sequencing data. PMID:33354434
Genetic diversity and population structure of eddoe taro in China using genome-wide SNP markers. PMID:33354429
In vivo diversification of target genomic sites using processive base deaminase fusions blocked by dCas9. PMID:33353963
Bi-Allelic Pathogenic Variations in MERTK Including Deletions Are Associated with an Early Onset Progressive Form of Retinitis Pigmentosa. PMID:33353011
Evidence for Divergent Selection on Immune Genes between the African Malaria Vectors, Anopheles coluzzii and A. gambiae. PMID:33352887
Rare and de novo coding variants in chromodomain genes in Chiari I malformation. PMID:33352116
Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis. PMID:33352111
Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency. PMID:33352108
The complexity of co-limitation: nutrigenomics reveal non-additive interactions of calcium and phosphorus on gene expression in Daphnia pulex. PMID:33352081
Population studies of the wild tomato species Solanum chilense reveal geographically structured major gene-mediated pathogen resistance. PMID:33352079
Phylogenomics of white-eyes, a 'great speciator', reveals Indonesian archipelago as the center of lineage diversity. PMID:33350381
A multicenter study benchmarking single-cell RNA sequencing technologies using reference samples. PMID:33349700
Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa. PMID:33349664
ARPIR: automatic RNA-Seq pipelines with interactive report. PMID:33349239
Nanopore RNA Sequencing Revealed Long Non-Coding and LTR Retrotransposon-Related RNAs Expressed at Early Stages of Triticale SEED Development. PMID:33348863
Conserved Imprinted Genes between Intra-Subspecies and Inter-Subspecies Are Involved in Energy Metabolism and Seed Development in Rice. PMID:33348666
Genomic surveillance of Neisseria meningitidis serogroup B invasive strains: Diversity of vaccine antigen types, Brazil, 2016-2018. PMID:33347452
Telomeric TART elements target the piRNA machinery in Drosophila. PMID:33347429
Evaluation of Homology-Independent CRISPR-Cas9 Off-Target Assessment Methods. PMID:33346710
Global Analysis of Gene Expression Profiles Provides Novel Insights into the Development and Evolution of the Large Crustacean Eriocheir sinensis. PMID:33346084
Deficiency of Vgll2 Gene Alters the Gene Expression Profiling of Skeletal Muscle Subjected to Mechanical Overload. PMID:33344964
DNA Damage Induces Dynamic Associations of BRD4/P-TEFb With Chromatin and Modulates Gene Transcription in a BRD4-Dependent and -Independent Manner. PMID:33344510
Genomic and Phenotypic Divergence in Wild Barley Driven by Microgeographic Adaptation. PMID:33344112
SSRgenotyper: A simple sequence repeat genotyping application for whole-genome resequencing and reduced representational sequencing projects. PMID:33344093
Comparative genomic analysis of the principal Cryptosporidium species that infect humans. PMID:33344091
Pervasive prophage recombination occurs during evolution of spore-forming Bacilli. PMID:33343000
Evaluation of Ion Torrent next-generation sequencing for thalassemia diagnosis. PMID:33342339
Simulation of African and non-African low and high coverage whole genome sequence data to assess variant calling approaches. PMID:33341897
Integrator is recruited to promoter-proximally paused RNA Pol II to generate Caenorhabditis elegans piRNA precursors. PMID:33340372
Male Linked Genomic Region Determines Sex in Dioecious Amaranthus palmeri. PMID:33340320
A region of the sex chromosome associated with population differences in diapause induction contains highly divergent alleles at clock genes. PMID:33340097
Evaluation of mutation rates, mosaicism and off target mutations when injecting Cas9 mRNA or protein for genome editing of bovine embryos. PMID:33339870
Genomic signatures of recombination in a natural population of the bdelloid rotifer Adineta vaga. PMID:33339818
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. PMID:33339817
Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome. PMID:33339352
A Revised Model of Anatomically Modern Human Expansions Out of Africa through a Machine Learning Approximate Bayesian Computation Approach. PMID:33339234
Phenotypic Characterization of Intellectual Disability Caused by MBOAT7 Mutation in Two Consanguineous Pakistani Families. PMID:33335874
A Distributed Whole Genome Sequencing Benchmark Study. PMID:33335541
The Neuromodulator-Encoding sadA Gene Is Widely Distributed in the Human Skin Microbiome. PMID:33335515
siRNA biogenesis and advances in topically applied dsRNA for controlling virus infections in tomato plants. PMID:33335295
Cerina: systematic circRNA functional annotation based on integrative analysis of ceRNA interactions. PMID:33335165
Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy. PMID:33335088
Elongin A associates with actively transcribed genes and modulates enhancer RNA levels with limited impact on transcription elongation rate in vivo. PMID:33334895
Thermal stress accelerates Arabidopsis thaliana mutation rate. PMID:33334733
FAN-C: a feature-rich framework for the analysis and visualisation of chromosome conformation capture data. PMID:33334380
Evolution of MicroRNA Biogenesis Genes in the Sterlet (Acipenser ruthenus) and Other Polyploid Vertebrates. PMID:33334059
RNA-Mediated Feedback Control of Transcriptional Condensates. PMID:33333019
Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor. PMID:33332735
Regionally diverse astrocyte subtypes and their heterogeneous response to EAE. PMID:33332631
The role of gene dosage in budding yeast centrosome scaling and spontaneous diploidization. PMID:33332348
Read trimming has minimal effect on bacterial SNP-calling accuracy. PMID:33332257
Whole-Genome Sequencing of Procyonids Reveals Distinct Demographic Histories in Kinkajou (Potos flavus) and Northern Raccoon (Procyon lotor). PMID:33331895
The First Draft Genome of a Cold-Water Coral Trachythela sp. (Alcyonacea: Stolonifera: Clavulariidae). PMID:33331875
Integrative characterization of the near-minimal bacterium Mesoplasma florum. PMID:33331123
Development of SNP-Based Genomic Tools for the Canadian Bison Industry: Parentage Verification and Subspecies Composition. PMID:33329724
RKDOSCNV: A Local Kernel Density-Based Approach to the Detection of Copy Number Variations by Using Next-Generation Sequencing Data. PMID:33329705
Draft Genome of the European Mouflon (Ovis orientalis musimon). PMID:33329689
Comparative Transcriptome Analyses of Longissimus thoracis Between Pig Breeds Differing in Muscle Characteristics. PMID:33329687
Analysis of Indian SARS-CoV-2 Genomes Reveals Prevalence of D614G Mutation in Spike Protein Predicting an Increase in Interaction With TMPRSS2 and Virus Infectivity. PMID:33329480
Splicing Endonuclease Is an Important Player in rRNA and tRNA Maturation in Archaea. PMID:33329479
DNA-Stable Isotope Probing Shotgun Metagenomics Reveals the Resilience of Active Microbial Communities to Biochar Amendment in Oxisol Soil. PMID:33329461
Metagenomic Association Analysis of Gut Symbiont Limosilactobacillus reuteri Without Host-Specific Genome Isolation. PMID:33329454
An ArcA-Modulated Small RNA in Pathogenic Escherichia coli K1. PMID:33329434
Hepatic Transcriptome Analysis Revealing the Molecular Pathogenesis of Type 2 Diabetes Mellitus in Zucker Diabetic Fatty Rats. PMID:33329383
RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease. PMID:33329316
Anti-tumour immunity induces aberrant peptide presentation in melanoma. PMID:33328638
Creation of bladder assembloids mimicking tissue regeneration and cancer. PMID:33328632
Measuring DNA mechanics on the genome scale. PMID:33328628
Clonal relationship and directionality of progression of synchronous endometrial and ovarian carcinomas in patients with DNA mismatch repair-deficiency associated syndromes. PMID:33328602
Brassicaceae transcriptomes reveal convergent evolution of super-accumulation of sinigrin. PMID:33328568
A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge. PMID:33328475
Melon short internode (CmSi) encodes an ERECTA-like receptor kinase regulating stem elongation through auxin signaling. PMID:33328451
High-quality de novo assembly of the Eucommia ulmoides haploid genome provides new insights into evolution and rubber biosynthesis. PMID:33328448
The mutation of ent-kaurene synthase, a key enzyme involved in gibberellin biosynthesis, confers a non-heading phenotype to Chinese cabbage (Brassica rapa L. ssp. pekinensis). PMID:33328441
The de novo genome assembly of Tapiscia sinensis and the transcriptomic and developmental bases of androdioecy. PMID:33328438
The apple DNA-binding one zinc-finger protein MdDof54 promotes drought resistance. PMID:33328433
Morphoagronomic characterization and whole-genome resequencing of eight highly diverse wild and weedy S. pimpinellifolium and S. lycopersicum var. cerasiforme accessions used for the first interspecific tomato MAGIC population. PMID:33328432
Fine mapping and identification of candidate genes for the peach powdery mildew resistance gene Vr3. PMID:33328431
Type I Interferon acts as a major barrier to the establishment of infectious bursal disease virus (IBDV) persistent infections. PMID:33328313
Genomic and phenotypic characterisation of invasive neonatal and colonising group B Streptococcus isolates from Slovenia, 2001-2018. PMID:33327946
Epigenome-wide association study for atrazine induced transgenerational DNA methylation and histone retention sperm epigenetic biomarkers for disease. PMID:33326428
Candidate Genetic Modifiers for RPGR Retinal Degeneration. PMID:33326016
Helixer: Cross-species gene annotation of large eukaryotic genomes using deep learning. PMID:33325516
aCLImatise: Automated generation of tool definitions for bioinformatics workflows. PMID:33325479
Plasmodium falciparum DHFR and DHPS Mutations Are Associated With HIV-1 Co-Infection and a Novel DHPS Mutation I504T Is Identified in Western Kenya. PMID:33324580
The virome from a collection of endomycorrhizal fungi reveals new viral taxa with unprecedented genome organization. PMID:33324490
A Retrotransposon Insertion in GhMML3_D12 Is Likely Responsible for the Lintless Locus li3 of Tetraploid Cotton. PMID:33324436
The Bactericidal Fatty Acid Mimetic 2CCA-1 Selectively Targets Pneumococcal Extracellular Polyunsaturated Fatty Acid Metabolism. PMID:33323510
Functional and genetic markers of niche partitioning among enigmatic members of the human oral microbiome. PMID:33323122
Toll-Like Receptor 7 Is Required for Lacrimal Gland Autoimmunity and Type 1 Diabetes Development in Male Nonobese Diabetic Mice. PMID:33322152
The ubiquitin ligase RFWD3 is required for translesion DNA synthesis. PMID:33321094
Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells. PMID:33321074
Protein quality control and regulated proteolysis in the genome-reduced organism Mycoplasma pneumoniae. PMID:33320415
In cis TP53 and RAD51C pathogenic variants may predispose to sebaceous gland carcinomas. PMID:33319852
Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis. PMID:33319550
Longitudinal characterization of HIV-1 pol-gene in treatment-naïve men-who-have-sex-with-men from acute to chronic infection stages. PMID:33319116
WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation. PMID:33318687
FXR mediates T cell-intrinsic responses to reduced feeding during infection. PMID:33318189
Convergent network effects along the axis of gene expression during prostate cancer progression. PMID:33317623
The Future of Livestock Management: A Review of Real-Time Portable Sequencing Applied to Livestock. PMID:33317066
Multiple Introductions Followed by Ongoing Community Spread of SARS-CoV-2 at One of the Largest Metropolitan Areas of Northeast Brazil. PMID:33316947
Identification of Novel CDH23 Variants Causing Moderate to Profound Progressive Nonsyndromic Hearing Loss. PMID:33316915
Selective amplification of hypermethylated DNA from diverse tumor types via MSRE-PCR. PMID:33315971
HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation. PMID:33315856
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner. PMID:33315488
Cardiac endothelial cells maintain open chromatin and expression of cardiomyocyte myofibrillar genes. PMID:33315013
Direct RNA sequencing dataset of SMG1 KO mutant Physcomitrella (Physcomitrium patens). PMID:33313367
Adaptive evolution at mRNA editing sites in soft-bodied cephalopods. PMID:33312772
Transcriptomic signatures and repurposing drugs for COVID-19 patients: findings of bioinformatics analyses. PMID:33312453
A Near-Chromosome Level Genome Assembly of Anopheles stephensi. PMID:33312190
Functional Gene Expression in Shark Bay Hypersaline Microbial Mats: Adaptive Responses. PMID:33312167
First Record of the Complete Mitochondrial Genome of a Saprotrophic and Opportunistic Human Pathogenic Fungus, Scopulariopsis brevicaulis. PMID:33312021
Local Variation in Recombination Rates of the Honey Bee (Apis mellifera) Genome among Samples from Six Disparate Populations. PMID:33311731
Nasopharyngeal carcinoma MHC region deep sequencing identifies HLA and novel non-HLA TRIM31 and TRIM39 loci. PMID:33311639
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis. PMID:33311468
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system. PMID:33310703
Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae. PMID:33306676
Weighted Gene Co-Expression Network Coupled with a Critical-Time-Point Analysis during Pathogenesis for Predicting the Molecular Mechanism Underlying Blast Resistance in Rice. PMID:33306159
Convergent Rewiring of the Virulence Regulatory Network Promotes Adaptation of Ralstonia solanacearum on Resistant Tomato. PMID:33306125
Jekyll or Hyde? The genome (and more) of Nesidiocoris tenuis, a zoophytophagous predatory bug that is both a biological control agent and a pest. PMID:33305885
The comparative genomic landscape of adaptive radiation in crater lake cichlid fishes. PMID:33305470
RNA sequencing data from osteochondroprogenitor populations in synovial joints of mice during murine model of rheumatoid arthritis. PMID:33304967
Protein Arginine Methyltransferase PRMT5 Regulates Fatty Acid Metabolism and Lipid Droplet Biogenesis in White Adipose Tissues. PMID:33304767
Enabling evolutionary studies at multiple scales in Apocynaceae through Hyb-Seq. PMID:33304663
A test for meiotic drive in hybrids between Australian and Timor zebra finches. PMID:33304552
Dissecting the binding mechanisms of transcription factors to DNA using a statistical thermodynamics framework. PMID:33304457
SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing. PMID:33304377
Gene Networks Underlying the Resistance of Bifidobacterium longum to Inflammatory Factors. PMID:33304352
Effect of Sulfate on Carbon Monoxide Conversion by a Thermophilic Syngas-Fermenting Culture Dominated by a Desulfofundulus Species. PMID:33304333
A Novel Homozygous Intronic Variant in TNNT2 Associates With Feline Cardiomyopathy. PMID:33304277
A biomolecular anthropological investigation of William Adams, the first SAMURAI from England. PMID:33303940
Gene expression profiling in neuronal cells identifies a different type of transcriptome modulated by NF-Y. PMID:33303918
Cell-cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness. PMID:33303824
Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency. PMID:33303747
A flexible computational pipeline for research analyses of unsolved clinical exome cases. PMID:33303739
Retrospective Analysis of the Relationship between Two Anthrax Outbreaks in Kazakhstan Based on Genomic Data. PMID:33303664
Complete Genome Sequence of an Australian Strain of the Lichen-Forming Fungus Endocarpon pusillum (Hedwig). PMID:33303659
Identification of Arctic Food Fish Species for Anthropogenic Contaminant Testing Using Geography and Genetics. PMID:33302601
Comparative Genomics of Xanthomonas citri pv. citri A* Pathotype Reveals Three Distinct Clades with Varying Plasmid Distribution. PMID:33302542
Genomic Analysis of Natural Rough Brucella melitensis Rev.1 Vaccine Strains: Identification and Characterization of Mutations in Key Genes Associated with Bacterial LPS Biosynthesis and Virulence. PMID:33302421
Sequencing facility and DNA source associated patterns of virus-mappable reads in whole-genome sequencing data. PMID:33301893
High-Throughput Genotyping Technologies in Plant Taxonomy. PMID:33301093
Origin of a Giant Sex Chromosome. PMID:33300980
H1 histones control the epigenetic landscape by local chromatin compaction. PMID:33299182
Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing. PMID:33298453
A Klebsiella pneumoniae ST307 outbreak clone from Germany demonstrates features of extensive drug resistance, hypermucoviscosity, and enhanced iron acquisition. PMID:33298160
Genomic and Transcriptomic Survey Provides New Insight into the Organization and Transposition Activity of Highly Expressed LTR Retrotransposons of Sunflower (Helianthus annuus L.). PMID:33297579
Proteome size reduction in Apicomplexans is linked with loss of DNA repair and host redundant pathways. PMID:33296723
Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria. PMID:33296702
The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State. PMID:33296649
Msuite: A High-Performance and Versatile DNA Methylation Data-Analysis Toolkit. PMID:33294868
The ecogenomics of dsDNA bacteriophages in feces of stabled and feral horses. PMID:33294140
Enzymatic biosynthesis of B-complex vitamins is supplied by diverse microbiota in the Rhodnius prolixus anterior midgut following Trypanosoma cruzi infection. PMID:33294135
Population genomic data in spider mites point to a role for local adaptation in shaping range shifts. PMID:33294025
Selective sweep analysis reveals extensive parallel selection traits between large white and Duroc pigs. PMID:33294024
Host plants and Wolbachia shape the population genetics of sympatric herbivore populations. PMID:33294020
Genetic architecture, demographic history, and genomic differentiation of Populus davidiana revealed by whole-genome resequencing. PMID:33294010
GRAS-Di system facilitates high-density genetic map construction and QTL identification in recombinant inbred lines of the wheat progenitor Aegilops tauschii. PMID:33293651
The vascular targeted citrus FLOWERING LOCUS T3 gene promotes non-inductive early flowering in transgenic Carrizo rootstocks and grafted juvenile scions. PMID:33293614
A validated lineage-derived somatic truth data set enables benchmarking in cancer genome analysis. PMID:33293579
SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome. PMID:33293552
Donkey genomes provide new insights into domestication and selection for coat color. PMID:33293529
A Mutation Upstream of the rplN-rpsD Ribosomal Operon Downregulates Bordetella pertussis Virulence Factor Production without Compromising Bacterial Survival within Human Macrophages. PMID:33293402
Characterisation of mobile genetic elements in Mycoplasma hominis with the description of ICEHo-II, a variant mycoplasma integrative and conjugative element. PMID:33292499
STARRPeaker: uniform processing and accurate identification of STARR-seq active regions. PMID:33292397
Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development. PMID:33292279
A systems biology framework integrating GWAS and RNA-seq to shed light on the molecular basis of sperm quality in swine. PMID:33292187
The Specific Carbohydrate Diet and Diet Modification as Induction Therapy for Pediatric Crohn's Disease: A Randomized Diet Controlled Trial. PMID:33291229
MINERVA: A Facile Strategy for SARS-CoV-2 Whole-Genome Deep Sequencing of Clinical Samples. PMID:33290743
Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids. PMID:33290741
Genome-wide integration site detection using Cas9 enriched amplification-free long-range sequencing. PMID:33290561
CoolMPS: evaluation of antibody labeling based massively parallel non-coding RNA sequencing. PMID:33290507
PEA15 loss of function and defective cerebral development in the domestic cat. PMID:33290415
Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α. PMID:33289482
Tools for experimental and computational analyses of off-target editing by programmable nucleases. PMID:33288953
Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads. PMID:33288906
Quantifying the influence of mutation detection on tumour subclonal reconstruction. PMID:33288765
Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression. PMID:33287884
Distinct mutation profiles between primary bladder cancer and circulating tumor cells warrant the use of circulating tumors cells as cellular resource for mutation follow-up. PMID:33287735
Linkage mapping and QTL analysis of flowering time using ddRAD sequencing with genotype error correction in Brassica napus. PMID:33287721
Genomic targets for high-resolution inference of kinship, ancestry and disease susceptibility in orang-utans (genus: Pongo). PMID:33287706
Dynamics of Whole-Genome Contacts of Nucleoli in Drosophila Cells Suggests a Role for rDNA Genes in Global Epigenetic Regulation. PMID:33287227
Transcriptomic Leaf Profiling Reveals Differential Responses of the Two Most Traded Coffee Species to Elevated [CO2]. PMID:33287164
Taking the next-gen step: Comprehensive antimicrobial resistance detection from Burkholderia pseudomallei. PMID:33285499
Using GRO-Seq to Measure Circadian Transcription and Discover Circadian Enhancers. PMID:33284441
iGenomics: Comprehensive DNA sequence analysis on your Smartphone. PMID:33284326
Recent advances in Cannabis sativa genomics research. PMID:33283274
Effect of EGLN1 Genetic Polymorphisms on Hemoglobin Concentration in Andean Highlanders. PMID:33282944
Accurate Prediction of a Quantitative Trait Using the Genes Controlling the Trait for Gene-Based Breeding in Cotton. PMID:33281846
The Signatures of Natural Selection and Molecular Evolution in Fusarium graminearum Virus 1. PMID:33281800
Exploring the Influence of Signal Molecules on Marine Biofilms Development. PMID:33281767
Meiotic Cells Counteract Programmed Retrotransposon Activation via RNA-Binding Translational Repressor Assemblies. PMID:33278343
RepeatProfiler: A pipeline for visualization and comparative analysis of repetitive DNA profiles. PMID:33277787
Whole genome sequence analysis of rice genotypes with contrasting response to salinity stress. PMID:33277598
Evolution of the potassium channel gene Kcnj13 underlies colour pattern diversification in Danio fish. PMID:33277491
Genetic Basis of Tiller Dynamics of Rice Revealed by Genome-Wide Association Studies. PMID:33276582
The Needle in the Haystack-Searching for Genetic and Epigenetic Differences in Monozygotic Twins Discordant for Tetralogy of Fallot. PMID:33276527
Mutation in histone deacetylase HDA-3 leads to shortened locomotor healthspan in Caenorhabditis elegans. PMID:33276344
Genomic epidemiology of nontoxigenic Corynebacterium diphtheriae from King County, Washington State, USA between July 2018 and May 2019. PMID:33275088
Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci. PMID:33274714
Evolution of Pseudomonas aeruginosa toward higher fitness under standard laboratory conditions. PMID:33273720
CCDC66 frameshift variant associated with a new form of early-onset progressive retinal atrophy in Portuguese Water Dogs. PMID:33273526
mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition. PMID:33273014
Genome Sequence of Vibrio nigripulchritudo Strain TUMSAT-TG-2018, Isolated from Diseased Pacific White Shrimp, Litopenaeus vannamei. PMID:33273004
Identification of novel alternative splicing biomarkers for breast cancer with LC/MS/MS and RNA-Seq. PMID:33272210
Soybean Thrips (Thysanoptera: Thripidae) Harbor Highly Diverse Populations of Arthropod, Fungal and Plant Viruses. PMID:33271916
Developmental remodelling of non-CG methylation at satellite DNA repeats. PMID:33271598
Structural modularity of the XIST ribonucleoprotein complex. PMID:33268787
Genetic Ancestry Contributes to Somatic Mutations in Lung Cancers from Admixed Latin American Populations. PMID:33268447
SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery. PMID:33268350
Moose genomes reveal past glacial demography and the origin of modern lineages. PMID:33267779
Transcriptomic profiles of non-embryogenic and embryogenic callus cells in a highly regenerative upland cotton line (Gossypium hirsutum L.). PMID:33267776
Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands. PMID:33267773
Genome-Wide Analysis of Nubian Ibex Reveals Candidate Positively Selected Genes That Contribute to Its Adaptation to the Desert Environment. PMID:33266380
Evaluation of Single-Molecule Sequencing Technologies for Structural Variant Detection in Two Swedish Human Genomes. PMID:33266238
The ADAR Family in Amphioxus: RNA Editing and Conserved Orthologous Site Predictions. PMID:33265998
A shotgun metagenomic investigation of the microbiota of udder cleft dermatitis in comparison to healthy skin in dairy cows. PMID:33264351
The Legacy of Recurrent Introgression during the Radiation of Hares. PMID:33263746
Dissecting the DNA binding landscape and gene regulatory network of p63 and p53. PMID:33263276
Deep whole-genome sequencing of multiple proband tissues and parental blood reveals the complex genetic etiology of congenital diaphragmatic hernias. PMID:33263113
Classification of Grain Amaranths Using Chromosome-Level Genome Assembly of Ramdana, A. hypochondriacus. PMID:33262776
Metagenomic analysis reveals a dynamic microbiome with diversified adaptive functions to utilize high lignocellulosic forages in the cattle rumen. PMID:33262428
Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity. PMID:33262343
Tet1 Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain. PMID:33262245
Amplification-free long-read sequencing reveals unforeseen CRISPR-Cas9 off-target activity. PMID:33261648
Intricate genetic variation networks control the adventitious root growth angle in apple. PMID:33261554
Finding a suitable library size to call variants in RNA-Seq. PMID:33261552
A Customizable Analysis Flow in Integrative Multi-Omics. PMID:33260881
Dichloromethane Degradation Pathway from Unsequenced Hyphomicrobium sp. MC8b Rapidly Explored by Pan-Proteomics. PMID:33260855
Impact of AHR Ligand TCDD on Human Embryonic Stem Cells and Early Differentiation. PMID:33260776
The Genomic Impact of Selection for Virulence against Resistance in the Potato Cyst Nematode, Globodera pallida. PMID:33260722
Evidence for the Dissemination to Humans of Methicillin-Resistant Staphylococcus aureus ST398 through the Pork Production Chain: A Study in a Portuguese Slaughterhouse. PMID:33260448
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis. PMID:33259802
Dissecting seed pigmentation-associated genomic loci and genes by employing dual approaches of reference-based and k-mer-based GWAS with 438 Glycine accessions. PMID:33259564
Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster. PMID:33257809
Specific capture and whole-genome phylogeography of Dolphin morbillivirus. PMID:33257791
Linkage analysis identifies an isolated strabismus locus at 14q12 overlapping with FOXG1 syndrome region. PMID:33257509
Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2. PMID:33256807
Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines. PMID:33256787
Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets. PMID:33256612
Whole genome sequencing identified a 16 kilobase deletion on ECA13 associated with distichiasis in Friesian horses. PMID:33256610
Deep sampling and pooled amplicon sequencing reveals hidden genic variation in heterogeneous rye accessions. PMID:33256606
Dissecting the Genetic Basis of Lateral and Central Spikelet Development and Grain Traits in Intermedium-Spike Barley (Hordeum vulgare Convar. Intermedium). PMID:33256118
Evolution of Homeologous Gene Expression in Polyploid Wheat. PMID:33255795
Transcriptional Remodeling Patterns in Murine Dendritic Cells Infected with Paracoccidioides brasiliensis: More Is Not Necessarily Better. PMID:33255176
Bracon brevicornis Genome Showcases the Potential of Linked-Read Sequencing in Identifying a Putative Complementary Sex Determiner Gene. PMID:33255162
Genomic analysis reveals an exogenous viral symbiont with dual functionality in parasitoid wasps and their hosts. PMID:33253317
Population genomic evidence that human and animal infections in Africa come from the same populations of Dracunculus medinensis. PMID:33253172
Systematic clustering algorithm for chromatin accessibility data and its application to hematopoietic cells. PMID:33253153
Bedrock radioactivity influences the rate and spectrum of mutation. PMID:33252037
Drought activates MYB41 orthologs and induces suberization of grapevine fine roots. PMID:33251473
Multi-Omics Analysis of the Effect of cAMP on Actinorhodin Production in Streptomyces coelicolor. PMID:33251203
The G-protein Coupled Receptor GPR8 Regulates Secondary Metabolism in Trichoderma reesei. PMID:33251193
The Draft Genome of Red Lechwe, Kobus leche leche. PMID:33250921
Early Cytokine Induction Upon Pseudomonas aeruginosa Infection in Murine Precision Cut Lung Slices Depends on Sensing of Bacterial Viability. PMID:33250899
Genetic and Functional Diversity of Pseudomonas aeruginosa in Patients With Chronic Obstructive Pulmonary Disease. PMID:33250886
Genome plasticity in Paramecium bursaria revealed by population genomics. PMID:33250052
Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer. PMID:33248470
The Evolutionary Dynamics of Genetic Incompatibilities Introduced by Duplicated Genes in Arabidopsis thaliana. PMID:33247726
Tirant Stealthily Invaded Natural Drosophila melanogaster Populations during the Last Century. PMID:33247725
A New Catalog of Structural Variants in 1,301 A. thaliana Lines from Africa, Eurasia, and North America Reveals a Signature of Balancing Selection at Defense Response Genes. PMID:33247723
Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H. PMID:33247206
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence. PMID:33247104
SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication. PMID:33247099
I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells. PMID:33246929
IRF-1 expressed in the inner cell mass of the porcine early blastocyst enhances the pluripotency of induced pluripotent stem cells. PMID:33246502
Identification and population genetic analyses of copy number variations in six domestic goat breeds and Bezoar ibexes using next-generation sequencing. PMID:33246410
Metabolic RNA labeling for probing RNA dynamics in bacteria. PMID:33245763
Allele-specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers. PMID:33245585
De Novo Genome Assembly of the Japanese Wheat Cultivar Norin 61 Highlights Functional Variation in Flowering Time and Fusarium-Resistant Genes in East Asian Genotypes. PMID:33244607
An improved de novo assembling and polishing of Solea senegalensis transcriptome shed light on retinoic acid signalling in larvae. PMID:33244091
Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing. PMID:33243990
Characteristics of viral specimens collected from asymptomatic and fatal cases of COVID-19. PMID:33243941
Molecular portrait of squamous cell carcinoma of the bovine horn evaluated by high-throughput targeted exome sequencing: a preliminary report. PMID:33243240
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development. PMID:33242395
Footprinting SHAPE-eCLIP Reveals Transcriptome-wide Hydrogen Bonds at RNA-Protein Interfaces. PMID:33242392
High-quality genome assembly of Metaphire vulgaris. PMID:33240640
Genomic characterization and phylogenetic analysis of Salmonella enterica serovar Javiana. PMID:33240617
Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients. PMID:33240314
Putative Epigenetic Biomarkers of Stress in Red Blood Cells of Chickens Reared Across Different Biomes. PMID:33240310
Metagenomic Characterization of the Microbiome and Resistome of Retail Ground Beef Products. PMID:33240224
A map of cis-regulatory elements and 3D genome structures in zebrafish. PMID:33239788
A haplotype-led approach to increase the precision of wheat breeding. PMID:33239669
The Human Adenovirus Type 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs. PMID:33239457
Plasma microRNA signature in presymptomatic and symptomatic subjects with C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis. PMID:33239440
Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules. PMID:33239396
A Bioinformatic Pipeline for Improved Genome Analysis and Clustering of Isolates during Outbreaks of Legionnaires' Disease. PMID:33239371
Use of Oxford Nanopore MinION to generate full-length sequences of the Blastocystis small subunit (SSU) rRNA gene. PMID:33239096
GWAS Based on RNA-Seq SNPs and High-Throughput Phenotyping Combined with Climatic Data Highlights the Reservoir of Valuable Genetic Diversity in Regional Tomato Landraces. PMID:33238469
A Two-Step Process of Effector Programming Governs CD4+ T Cell Fate Determination Induced by Antigenic Activation in the Steady State. PMID:33238127
Siberian sturgeon multi-tissue reference transcriptome database. PMID:33238003
HP1γ regulates H3K36 methylation and pluripotency in embryonic stem cells. PMID:33237287
High Resolution analysis of Transmission Dynamics of Sars-Cov-2 in Two Major Hospital Outbreaks in South Africa Leveraging Intrahost Diversity. PMID:33236025
High resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies. PMID:33236010
Genetic mapping and candidate gene analysis for melon resistance to Phytophthora capsici. PMID:33235270
Daily transcriptomes of the copepod Calanus finmarchicus during the summer solstice at high Arctic latitudes. PMID:33235200
Method comparison of targeted influenza A virus typing and whole-genome sequencing from respiratory specimens of companion animals. PMID:33234046
Currently Applied Molecular Assays for Identifying ESR1 Mutations in Patients with Advanced Breast Cancer. PMID:33233830
New Transcriptome-Based SNP Markers for Noug (Guizotia abyssinica) and Their Conversion to KASP Markers for Population Genetics Analyses. PMID:33233626
QTL Mapping for Resistance to Cankers Induced by Pseudomonas syringae pv. actinidiae (Psa) in a Tetraploid Actinidia chinensis Kiwifruit Population. PMID:33233616
Physiological Changes in Barley mlo-11 Powdery Mildew Resistance Conditioned by Tandem Repeat Copy Number. PMID:33233522
Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage. PMID:33232656
Population demographic history and population structure for Pakistani Nili-Ravi breeding bulls based on SNP genotyping to identify genomic regions associated with male effects for milk yield and body weight. PMID:33232358
Semiochemical responsive olfactory sensory neurons are sexually dimorphic and plastic. PMID:33231170
RepeatFS: a file system providing reproducibility through provenance and automation. PMID:33230554
DNA Methyltransferase 3A Is Involved in the Sustained Effects of Chronic Stress on Synaptic Functions and Behaviors. PMID:33230530
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing. PMID:33230297
Marine Dadabacteria exhibit genome streamlining and phototrophy-driven niche partitioning. PMID:33230264
Limits to the cellular control of sequestered cryptophyte prey in the marine ciliate Mesodinium rubrum. PMID:33230263
Turnip mosaic virus in oilseed rape activates networks of sRNA-mediated interactions between viral and host genomes. PMID:33230160
ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine. PMID:33230096
Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2. PMID:33229462
Variation under domestication in animal models: the case of the Mexican axolotl. PMID:33228551
Integrative analysis of structural variations using short-reads and linked-reads yields highly specific and sensitive predictions. PMID:33226985
Origins and Long-Term Patterns of Copy-Number Variation in Rhesus Macaques. PMID:33226085
A machine learning framework to determine geolocations from metagenomic profiling. PMID:33225966
Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences. PMID:33225957
Next generation sequencing of RB1gene for the molecular diagnosis of ethnic minority with retinoblastoma in Yunnan. PMID:33225895
Phenotypic and Genomic Analysis of Clostridium beijerinckii NRRL B-598 Mutants With Increased Butanol Tolerance. PMID:33224939
Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation. PMID:33223527
Mycoplasma bovis Infections in Free-Ranging Pronghorn, Wyoming, USA. PMID:33219651
The strength and form of natural selection on transcript abundance in the wild. PMID:33219570
Variable Spontaneous Mutation and Loss of Heterozygosity among Heterozygous Genomes in Yeast. PMID:33219379
Fairy circles in Namibia are assembled from genetically distinct grasses. PMID:33219348
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers. PMID:33219226
Dominant subtype switch in avian influenza viruses during 2016-2019 in China. PMID:33219213
Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients. PMID:33219095
The origin and evolution of a distinct mechanism of transcription initiation in yeasts. PMID:33219055
Dynamic and reversible DNA methylation changes induced by genome separation and merger of polyploid wheat. PMID:33218336
F-box protein CFK1 interacts with and degrades de novo DNA methyltransferase in Arabidopsis. PMID:33216996
Novel small RNAs expressed by Bartonella bacilliformis under multiple conditions reveal potential mechanisms for persistence in the sand fly vector and human host. PMID:33216745
Comparative Genomics of Strictly Vertically Transmitted, Feminizing Microsporidia Endosymbionts of Amphipod Crustaceans. PMID:33216144
Localized effect of treated wastewater effluent on the resistome of an urban watershed. PMID:33215210
Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae. PMID:33214631
Genomic determinants for initiation and length of natural antisense transcripts in Entamoeba histolytica. PMID:33214622
LOXL2 promotes aggrecan and gender-specific anabolic differences to TMJ cartilage. PMID:33214607
High-Quality Sequencing, Assembly, and Annotation of the Streptomyces griseofuscus DSM 40191 Genome. PMID:33214305
Draft Genome Sequences of Four Bacterial Species as Part of an Experiential Microbiology Project at SUNY Geneseo. PMID:33214303
Draft Whole-Genome Sequence of the Alkane-Synthesizing Polar Cyanobacterium Pseudanabaena biceps Strain O-153. PMID:33214296
Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus. PMID:33213505
A genome-wide scan study identifies a single nucleotide substitution in MC1R gene associated with white coat colour in fallow deer (Dama dama). PMID:33213385
Contrasting genetic variation and positive selection followed the divergence of NBS-encoding genes in Asian and European pears. PMID:33213380
Genomic and Transcriptomic Analysis for Identification of Genes and Interlinked Pathways Mediating Artemisinin Resistance in Leishmania donovani. PMID:33213096
Genomic Analysis Revealed a Convergent Evolution of LINE-1 in Coat Color: A Case Study in Water Buffaloes (Bubalus bubalis). PMID:33212507
The Early Evolution of Oral Poliovirus Vaccine Is Shaped by Strong Positive Selection and Tight Transmission Bottlenecks. PMID:33212020
Safety and Efficacy of CR6261 in an Influenza A H1N1 Healthy Human Challenge Model. PMID:33211860
Characterising the epidemic spread of influenza A/H3N2 within a city through phylogenetics. PMID:33211775
Gene expression responses to Zika virus infection in peripheral blood mononuclear cells from pregnant and non-pregnant women. PMID:33211409
Stochastic Gain and Loss of Novel Transcribed Open Reading Frames in the Human Lineage. PMID:33210146
Reconstructing the Invasion Route of the P-Element in Drosophila melanogaster Using Extant Population Samples. PMID:33210145
Search for Viral Infections in Cerebrospinal Fluid From Patients With Autoimmune Encephalitis. PMID:33209955
RNA nucleation by MSL2 induces selective X chromosome compartmentalization. PMID:33208948
Defining HPV-specific B cell responses in patients with head and neck cancer. PMID:33208941
Anaerobic bacterial degradation of protein and lipid macromolecules in subarctic marine sediment. PMID:33208892
Machine learning approaches reveal genomic regions associated with sugarcane brown rust resistance. PMID:33208862
Genome-enabled discovery of anthraquinone biosynthesis in Senna tora. PMID:33208749
Optimizing performance of GATK workflows using Apache Arrow In-Memory data framework. PMID:33208101
Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells. PMID:33207246
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation. PMID:33207202
BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils. PMID:33207187
Variation in intrinsic resistance of pea aphids to parasitoid wasps: A transcriptomic basis. PMID:33206703
Genomic analysis of trimethoprim-resistant extraintestinal pathogenic Escherichia coli and recurrent urinary tract infections. PMID:33206038
The transcriptome dynamics of single cells during the cell cycle. PMID:33205894
Unifying package managers, workflow engines, and containers: Computational reproducibility with BioNix. PMID:33205815
Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates. PMID:33205751
Transgenic goats producing an improved version of cetuximab in milk. PMID:33205005
Using RNA Sequencing and Spike-in RNAs to Measure Intracellular Abundance of lncRNAs and mRNAs. PMID:33204768
Somatic mutational landscapes of adherens junctions and their functional consequences in cutaneous melanoma development. PMID:33204327
Genomic selection for heterobothriosis resistance concurrent with body size in the tiger pufferfish, Takifugu rubripes. PMID:33203997
XPC deficiency increases risk of hematologic malignancies through mutator phenotype and characteristic mutational signature. PMID:33203900
Transcriptome and genome sequencing elucidates the molecular basis for the high yield and good quality of the hybrid rice variety Chuanyou6203. PMID:33203889
Highly accurate long-read HiFi sequencing data for five complex genomes. PMID:33203859
SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients. PMID:33203694
Genetic Adaptation of Coxsackievirus B1 during Persistent Infection in Pancreatic Cells. PMID:33203081
Identification and Characterization of Hypothalamic Alternative Splicing Events and Variants in Ovine Fecundity-Related Genes. PMID:33203033
Genomic Diversity and Evolution of Quasispecies in Newcastle Disease Virus Infections. PMID:33202558
RNF213 gene mutation in circulating tumor DNA detected by targeted next-generation sequencing in the assisted discrimination of early-stage lung cancer from pulmonary nodules. PMID:33200540
Marfan syndrome: whole-exome sequencing reveals de novo mutations, second gene and genotype-phenotype correlations in the Chinese population. PMID:33200202
A Distinct Phylogenetic Cluster of Indian Severe Acute Respiratory Syndrome Coronavirus 2 Isolates. PMID:33200080
Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis. PMID:33199862
Transcriptome-based design of antisense inhibitors potentiates carbapenem efficacy in CRE Escherichia coli. PMID:33199638
Regulatory Elements Inserted into AAVs Confer Preferential Activity in Cortical Interneurons. PMID:33199411
Evaluation of the efficiency of genomic versus pedigree predictions for growth and wood quality traits in Scots pine. PMID:33198692
A comprehensive analysis of cotton VQ gene superfamily reveals their potential and extensive roles in regulating cotton abiotic stress. PMID:33198654
iCLIP analysis of RNA substrates of the archaeal exosome. PMID:33198623
Soybean Viromes in the Republic of Korea Revealed by RT-PCR and Next-Generation Sequencing. PMID:33198273
Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification. PMID:33196781
Unbiased Subgenome Evolution in Allotetraploid Species of Ephedra and Its Implications for the Evolution of Large Genomes in Gymnosperms. PMID:33196777
Combining artificial intelligence: deep learning with Hi-C data to predict the functional effects of non-coding variants. PMID:33196774
Long-read RNA sequencing of human and animal filarial parasites improves gene models and discovers operons. PMID:33196647
Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia. PMID:33196013
Field-Adapted Full Genome Sequencing of Peste-Des-Petits-Ruminants Virus Using Nanopore Sequencing. PMID:33195515
Virome Sequencing of the Human Intestinal Mucosal-Luminal Interface. PMID:33194818
Molecular Profiling Reveals Common and Specific Development Processes in Different Types of Gynecologic Cancers. PMID:33194730
The Bacteria Genome Pipeline (BAGEP): an automated, scalable workflow for bacteria genomes with Snakemake. PMID:33194387
Biases in genome reconstruction from metagenomic data. PMID:33194386
Broadening the Applicability of a Custom Multi-Platform Panel of Microhaplotypes: Bio-Geographical Ancestry Inference and Expanded Reference Data. PMID:33193704
Global Analysis of Transcription Start Sites in the New Ovine Reference Genome (Oar rambouillet v1.0). PMID:33193703
Transcriptome Analyses of β-Thalassemia -28(A>G) Mutation Using Isogenic Cell Models Generated by CRISPR/Cas9 and Asymmetric Single-Stranded Oligodeoxynucleotides (assODNs). PMID:33193694
A Family Affected by a Life-Threatening Erythrocyte Defect Caused by Pyruvate Kinase Deficiency With Normal Iron Status: A Case Report. PMID:33193643
Pronounced Plastic and Evolutionary Responses to Unpredictable Thermal Fluctuations in Drosophila simulans. PMID:33193631
Exome Sequencing of Native Populations From the Amazon Reveals Patterns on the Peopling of South America. PMID:33193622
Next Generation Sequencing and Bioinformatics Analysis of Family Genetic Inheritance. PMID:33193618
NRG1, PIP4K2A, and HTR2C as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder. PMID:33193575
Insights Into the Albinism Mechanism for Two Distinct Color Morphs of Northern Snakehead, Channa argus Through Histological and Transcriptome Analyses. PMID:33193565
Analysis of QTL DM4.1 for Downy Mildew Resistance in Cucumber Reveals Multiple subQTL: A Novel RLK as Candidate Gene for the Most Important subQTL. PMID:33193500
Genome-Wide Analysis of the Malaria Parasite Plasmodium falciparum Isolates From Togo Reveals Selective Signals in Immune Selection-Related Antigen Genes. PMID:33193320
Brd/BET Proteins Influence the Genome-Wide Localization of the Kaposi's Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Major Latency Proteins. PMID:33193257
A Shiga Toxin-Encoding Prophage Recombination Event Confounds the Phylogenetic Relationship Between Two Isolates of Escherichia coli O157:H7 From the Same Patient. PMID:33193248
Analysis Shiga Toxin-Encoding Bacteriophage in a Rare Strain of Shiga Toxin-Producing Escherichia coli O157:H7 stx2a/stx2c. PMID:33193199
Simultaneous quantification of mRNA and protein in single cells reveals post-transcriptional effects of genetic variation. PMID:33191917
Increased processing of SINE B2 ncRNAs unveils a novel type of transcriptome deregulation in amyloid beta neuropathology. PMID:33191914
Germline variants of DNA repair genes in early onset mantle cell lymphoma. PMID:33191405
A Trypanosoma cruzi zinc finger protein that is implicated in the control of epimastigote-specific gene expression and metacyclogenesis. PMID:33190649
Transductomics: sequencing-based detection and analysis of transduced DNA in pure cultures and microbial communities. PMID:33190645
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology. PMID:33190043
Remodeling of the m6A landscape in the heart reveals few conserved post-transcriptional events underlying cardiomyocyte hypertrophy. PMID:33188779
Enrichment and physiological characterization of a novel comammox Nitrospira indicates ammonium inhibition of complete nitrification. PMID:33188298
ATAC-seq with unique molecular identifiers improves quantification and footprinting. PMID:33188264
Synergistic biodegradation of aromatic-aliphatic copolyester plastic by a marine microbial consortium. PMID:33188179
A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits. PMID:33188033
Dedifferentiation and neuronal repression define familial Alzheimer's disease. PMID:33188013
Insertion variants missing in the human reference genome are widespread among human populations. PMID:33187521
Positive selection alone is sufficient for whole genome differentiation at the early stage of speciation process in the fall armyworm. PMID:33187468
Colony-Level Effects of Amygdalin on Honeybees and Their Microbes. PMID:33187240
The Medical Triazole Voriconazole Can Select for Tandem Repeat Variations in Azole-Resistant Aspergillus Fumigatus Harboring TR34/L98H Via Asexual Reproduction. PMID:33187077
Data Sanitization to Reduce Private Information Leakage from Functional Genomics. PMID:33186529
Assessing the Ability of Developmentally Precocious Estrogen Signaling to Recapitulate Ovarian Transcriptomes and Follicle Dynamics in Alligators from a Contaminated Lake. PMID:33186072
Systematic comparison and assessment of RNA-seq procedures for gene expression quantitative analysis. PMID:33184454
Adaptation by copy number variation increases insecticide resistance in the fall armyworm. PMID:33184418
Fungal-bacterial interaction selects for quorum sensing mutants with increased production of natural antifungal compounds. PMID:33184402
Human transcription factors responsive to initial reprogramming predominantly undergo legitimate reprogramming during fibroblast conversion to iPSCs. PMID:33184372
Shotgun sequencing of the vaginal microbiome reveals both a species and functional potential signature of preterm birth. PMID:33184260
A human cell atlas of fetal chromatin accessibility. PMID:33184180
Complete Genome Sequence of a Canadian Klebsiella michiganensis Strain, Obtained Using Oxford Nanopore Technologies Sequencing. PMID:33184156
Deeply Sequenced Infectious Clones of Key Cassava Begomovirus Isolates from Cameroon. PMID:33184153
Global Picture of Genetic Relatedness and the Evolution of Humankind. PMID:33182715
CitrusKB: a comprehensive knowledge base for transcriptome and interactome of Citrus spp. infected by Xanthomonas citri subsp. citri at different infection stages. PMID:33181825
Ten simple rules for writing a paper about scientific software. PMID:33180774
Long inverted repeats around the chromosome replication terminus in the model strain Bacillus thuringiensis serovar israelensis BGSC 4Q7. PMID:33180015
Genome-scale target capture of mitochondrial and nuclear environmental DNA from water samples. PMID:33179423
Development of a highly efficient 50K single nucleotide polymorphism genotyping array for the large and complex genome of Norway spruce (Picea abies L. Karst) by whole genome resequencing and its transferability to other spruce species. PMID:33179386
Galaxy CLIP-Explorer: a web server for CLIP-Seq data analysis. PMID:33179042
The Effect of Atopic Dermatitis and Diet on the Skin Transcriptome in Staffordshire Bull Terriers. PMID:33178726
Transcription Terminator-Mediated Enhancement in Transgene Expression in Maize: Preponderance of the AUGAAU Motif Overlapping With Poly(A) Signals. PMID:33178242
Molecular Epidemiology of Acinetobacter calcoaceticus-Acinetobacter baumannii Complex Isolated From Children at the Hospital Infantil de México Federico Gómez. PMID:33178158
A comparative genomics multitool for scientific discovery and conservation. PMID:33177664
A paternally inherited 1.4 kb deletion of the 11p15.5 imprinting center 2 is associated with a mild familial Silver-Russell syndrome phenotype. PMID:33177595
The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice. PMID:33177522
OsChz1 acts as a histone chaperone in modulating chromatin organization and genome function in rice. PMID:33177521
Unexpected Discovery and Expression of Amphibian Class II Endogenous Retroviruses. PMID:33177199
A new method for long-read sequencing of animal mitochondrial genomes: application to the identification of equine mitochondrial DNA variants. PMID:33176683
Decoding myofibroblast origins in human kidney fibrosis. PMID:33176333
ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. PMID:33176148
Rapid and Scalable Profiling of Nascent RNA with fastGRO. PMID:33176136
A highly differentiated region of wheat chromosome 7AL encodes a Pm1a immune receptor that recognizes its corresponding AvrPm1a effector from Blumeria graminis. PMID:33176001
HRIBO: high-throughput analysis of bacterial ribosome profiling data. PMID:33175953
RNA-seq analysis identifies cytoskeletal structural genes and pathways for meat quality in beef. PMID:33175867
Identification and Quantification of Small RNAs. PMID:33175381
Identification of a novel missense c.386G > A variant in a boy with the POMGNT1-related muscular dystrophy-dystroglycanopathy. PMID:33175337
Genome sequence of Hydrangea macrophylla and its application in analysis of the double flower phenotype. PMID:33175097
Genomic characterization of five commonly used endometrial cancer cell lines. PMID:33174010
Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of Aspergillus fumigatus. PMID:33173866
The translational landscape of SARS-CoV-2 and infected cells. PMID:33173862
Conservation genomics and pollination biology of an endangered, edaphic-endemic, octoploid herb: El Dorado bedstraw (Galium californicum subsp. sierrae; Rubiaceae). PMID:33173616
Identification of Zinc-Dependent Mechanisms Used by Group B Streptococcus To Overcome Calprotectin-Mediated Stress. PMID:33173000
Seasonal and diel patterns of abundance and activity of viruses in the Red Sea. PMID:33172994
Genome-Scale Mapping Reveals Complex Regulatory Activities of RpoN in Yersinia pseudotuberculosis. PMID:33172972
Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis. PMID:33172933
Genomic profile of MYCN non-amplified neuroblastoma and potential for immunotherapeutic strategies in neuroblastoma. PMID:33172452
Search for New Allergens in Lolium perenne Pollen Growing under Different Air Pollution Conditions by Comparative Transcriptome Study. PMID:33172209
A Novel Anphevirus in Aedes albopictus Mosquitoes Is Distributed Worldwide and Interacts with the Host RNA Interference Pathway. PMID:33172032
Environmental DNA Metabarcoding as a Means of Estimating Species Diversity in an Urban Aquatic Ecosystem. PMID:33171859
Contrasted histories of organelle and nuclear genomes underlying physiological diversification in a grass species. PMID:33171085
Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations. PMID:33170902
A functional variant on 20q13.33 related to glioma risk alters enhancer activity and modulates expression of multiple genes. PMID:33169458
A genomic catalog of Earth's microbiomes. PMID:33169036
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm. PMID:33168940
Identification of candidate genetic variants and altered protein expression in neural stem and mature neural cells support altered microtubule function to be an essential component in bipolar disorder. PMID:33168801
Oncogenic allelic interaction in Xiphophorus highlights hybrid incompatibility. PMID:33168740
Comparative assessments of indel annotations in healthy and cancer genomes with next-generation sequencing data. PMID:33167946
Assessment of Imputation from Low-Pass Sequencing to Predict Merit of Beef Steers. PMID:33167493
Genomic Characterization of Salmonella Minnesota Clonal Lineages Associated with Poultry Production in Brazil. PMID:33167341
LegumeIP V3: from models to crops-an integrative gene discovery platform for translational genomics in legumes. PMID:33166388
Identifying genetic variants associated with ritodrine-induced pulmonary edema. PMID:33166306
Investigating hospital Mycobacterium chelonae infection using whole genome sequencing and hybrid assembly. PMID:33166284
A frog with three sex chromosomes that co-mingle together in nature: Xenopus tropicalis has a degenerate W and a Y that evolved from a Z chromosome. PMID:33166278
Arioc: High-concurrency short-read alignment on multiple GPUs. PMID:33166275
Integrative genomic phylogeography reveals signs of mitonuclear incompatibility in a natural hybrid goby population. PMID:33165944
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes. PMID:33164753
IS26-mediated amplification of blaOXA-1 and blaCTX-M-15 with concurrent outer membrane porin disruption associated with de novo carbapenem resistance in a recurrent bacteraemia cohort. PMID:33164081
Approaching RNA-seq for Cell Line Identification. PMID:33163581
Technical Validation of a Hepatitis C Virus Whole Genome Sequencing Assay for Detection of Genotype and Antiviral Resistance in the Clinical Pathway. PMID:33162957
Genomic analysis of circular RNAs in heart. PMID:33160353
Genetic analyses of lodging resistance and yield provide insights into post-Green-Revolution breeding in rice. PMID:33159401
A Recessively Inherited Risk Locus on Chromosome 13q22-31 Conferring Susceptibility to Schizophrenia. PMID:33159203
Epigenetic and Transcriptional Control of the Epidermal Growth Factor Receptor Regulates the Tumor Immune Microenvironment in Pancreatic Cancer. PMID:33158848
High-quality bacterial genomes of a partial-nitritation/anammox system by an iterative hybrid assembly method. PMID:33158461
Aging Induces Profound Changes in sncRNA in Rat Sperm and These Changes Are Modified by Perinatal Exposure to Environmental Flame Retardant. PMID:33158036
Increased chromosomal instability characterizes metastatic renal cell carcinoma. PMID:33157517
Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation. PMID:33157031
Arrayed CRISPRi and quantitative imaging describe the morphotypic landscape of essential mycobacterial genes. PMID:33155979
YODA Kinase Controls a Novel Immune Pathway of Tomato Conferring Enhanced Disease Resistance to the Bacterium Pseudomonas syringae. PMID:33154763
Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data. PMID:33154511
Prediction of mitochondrial genome-wide variation through sequencing of mitochondrion-enriched extracts. PMID:33154458
Early medieval genetic data from Ural region evaluated in the light of archaeological evidence of ancient Hungarians. PMID:33154399
Transcriptomic response of Gordonia sp. strain NB4-1Y when provided with 6:2 fluorotelomer sulfonamidoalkyl betaine or 6:2 fluorotelomer sulfonate as sole sulfur source. PMID:33150552
Evolution from adherent to suspension: systems biology of HEK293 cell line development. PMID:33149219
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons. PMID:33149216
Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo. PMID:33149210
Epigenome-wide association study for pesticide (Permethrin and DEET) induced DNA methylation epimutation biomarkers for specific transgenerational disease. PMID:33148267
Towards a better understanding of the low recall of insertion variants with short-read based variant callers. PMID:33148192
Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene. PMID:33148170
First Phylogenetic Analysis of Malian SARS-CoV-2 Sequences Provides Molecular Insights into the Genomic Diversity of the Sahel Region. PMID:33147840
Patterns of RNA Editing in Newcastle Disease Virus Infections. PMID:33147786
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection. PMID:33147444
Bacterial genome editing by coupling Cre-lox and CRISPR-Cas9 systems. PMID:33147260
Identification and Characterization of Base-Substitution Mutations in the Macronuclear Genome of the Ciliate Tetrahymena thermophila. PMID:33146387
Genomic Architecture of Rapid Parallel Adaptation to Fresh Water in a Wild Fish. PMID:33146383
Selective Sweeps in a Nutshell: The Genomic Footprint of Rapid Insecticide Resistance Evolution in the Almond Agroecosystem. PMID:33146372
Feral populations of Brassica oleracea along Atlantic coasts in western Europe. PMID:33145003
Genome structure and content of the rice root-knot nematode (Meloidogyne graminicola). PMID:33144944
Genetic adaptation of Tibetan poplar (Populus szechuanica var. tibetica) to high altitudes on the Qinghai-Tibetan Plateau. PMID:33144942
Transformation of nonencapsulated Streptococcus pneumoniae during systemic infection. PMID:33144660
The transition from primary colorectal cancer to isolated peritoneal malignancy is associated with an increased tumour mutational burden. PMID:33144643
Tissue-specific patterns of regulatory changes underlying gene expression differences among Ficedula flycatchers and their naturally occurring F1 hybrids. PMID:33144405
High-Density Linkage Maps Based on Genotyping-by-Sequencing (GBS) Confirm a Chromosome-Level Genome Assembly and Reveal Variation in Recombination Rate for the Pacific Oyster Crassostrea gigas. PMID:33144392
Geothermal Gases Shape the Microbial Community of the Volcanic Soil of Pantelleria, Italy. PMID:33144309
Intra-host non-synonymous diversity at a neutralizing antibody epitope of SARS-CoV-2 spike protein N-terminal domain. PMID:33144203
A Novel Mutation of the NARROW LEAF 1 Gene Adversely Affects Plant Architecture in Rice (Oryza sativa L.). PMID:33143090
Genotypic and Phenotypic Changes in Candida albicans as a Result of Cold Plasma Treatment. PMID:33143065
Whole-Transcriptome Sequencing-Based Analysis of DAZL and Its Interacting Genes during Germ Cells Specification and Zygotic Genome Activation in Chickens. PMID:33142918
Utilizing PacBio Iso-Seq for Novel Transcript and Gene Discovery of Abiotic Stress Responses in Oryza sativa L. PMID:33142722
Transcriptome analysis of turkey (Meleagris gallopavo) reproductive tract revealed key pathways regulating spermatogenesis and post-testicular sperm maturation. PMID:33142529
Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2. PMID:33142113
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs. PMID:33141865
Plant invasion impacts on fungal community structure and function depend on soil warming and nitrogen enrichment. PMID:33141324
The caffeoyl-CoA O-methyltransferase gene SNP replacement in Russet Burbank potato variety enhances late blight resistance through cell wall reinforcement. PMID:33141312
Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse. PMID:33140451
Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity. PMID:33139957
Phased diploid genome assemblies and pan-genomes provide insights into the genetic history of apple domestication. PMID:33139952
Symbiosis, virulence and natural-product biosynthesis in entomopathogenic bacteria are regulated by a small RNA. PMID:33139881
Single-cell RNA profiling links ncRNAs to spatiotemporal gene expression during C. elegans embryogenesis. PMID:33139759
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males. PMID:33139741
Two centuries of monarch butterfly collections reveal contrasting effects of range expansion and migration loss on wing traits. PMID:33139548
Evolution of Colistin Resistance in the Klebsiella pneumoniae Complex Follows Multiple Evolutionary Trajectories with Variable Effects on Fitness and Virulence Characteristics. PMID:33139278
NGS-based expanded carrier screening for genetic disorders in North Indian population reveals unexpected results - a pilot study. PMID:33138774
Expanding the Geographic Characterisation of Epstein-Barr Virus Variation through Gene-Based Approaches. PMID:33138327
NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program. PMID:33138022
crAssphage genomes identified in fecal samples of an adult and infants with evidence of positive genomic selective pressure within tail protein genes. PMID:33137401
Plant-ImputeDB: an integrated multiple plant reference panel database for genotype imputation. PMID:33137192
Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2. PMID:33137177
Opposing functions of Fng1 and the Rpd3 HDAC complex in H4 acetylation in Fusarium graminearum. PMID:33137093
A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation. PMID:33135541
Diagnosing mild traumatic brain injury using saliva RNA compared to cognitive and balance testing. PMID:33135344
STAMP: a multiplex sequencing method for simultaneous evaluation of mitochondrial DNA heteroplasmies and content. PMID:33134911
TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro. PMID:33134768
Genomic Epidemiology of Salmonella Infantis in Ecuador: From Poultry Farms to Human Infections. PMID:33134346
A Recently Formed Triploid Cardamine insueta Inherits Leaf Vivipary and Submergence Tolerance Traits of Parents. PMID:33133153
Intra-Strain Genetic Variation of Platyfish (Xiphophorus maculatus) Strains Determines Tumorigenic Trajectory. PMID:33133148
Warming Climate Is Reducing the Diversity of Dominant Microbes in the Largest High Arctic Lake. PMID:33133035
Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. PMID:33128895
Single-cell analysis of AIMP2 splice variants informs on drug sensitivity and prognosis in hematologic cancer. PMID:33128014
Genomic surveillance of COVID-19 cases in Beijing. PMID:33127911
A Founder Effect Led Early SARS-CoV-2 Transmission in Spain. PMID:33127745
Uncovering the genomic potential of the Amazon River microbiome to degrade rainforest organic matter. PMID:33126925
Illuminating the dark side of the human transcriptome with long read transcript sequencing. PMID:33126848
Sources of variation of DNA methylation in rainbow trout: combined effects of temperature and genetic background. PMID:33126823
Amino Acid k-mer Feature Extraction for Quantitative Antimicrobial Resistance (AMR) Prediction by Machine Learning and Model Interpretation for Biological Insights. PMID:33126516
Sequence Transpositions Restore Genes on the Highly Degenerated W Chromosomes of Songbirds. PMID:33126459
Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition. PMID:33125893
Genomes of Pleistocene Siberian Wolves Uncover Multiple Extinct Wolf Lineages. PMID:33125870
Circulating mitochondrial genes detect acute cardiac allograft rejection: Role of the mitochondrial calcium uniporter complex. PMID:33125788
Geographically structured genomic diversity of non-human primate-infecting Treponema pallidum subsp. pertenue. PMID:33125317
ATACdb: a comprehensive human chromatin accessibility database. PMID:33125076
HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages. PMID:33123128
An extreme-phenotype genome-wide association study identifies candidate cannabinoid pathway genes in Cannabis. PMID:33122674
Complete and Circularized Genome Assemblies of the Kroppenstedtia eburnea Genus Type Strain and the Kroppenstedtia pulmonis Species Type Strain with MiSeq and MinION Sequence Data. PMID:33122418
Fitness effects for Ace insecticide resistance mutations are determined by ambient temperature. PMID:33121485
Ecological Structuring of Temperate Bacteriophages in the Inflammatory Bowel Disease-Affected Gut. PMID:33121006
HeRA: an atlas of enhancer RNAs across human tissues. PMID:33119754
The sockeye salmon genome, transcriptome, and analyses identifying population defining regions of the genome. PMID:33119641
DNA methylation in canine brains is related to domestication and dog-breed formation. PMID:33119634
Capture-based enrichment of Theileria parva DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional intra-specific genetic diversity. PMID:33119590
Antimicrobial Prodrug Activation by the Staphylococcal Glyoxalase GloB. PMID:33118347
Desert truffle genomes reveal their reproductive modes and new insights into plant-fungal interaction and ectendomycorrhizal lifestyle. PMID:33118170
PHF20 Promotes Glioblastoma Cell Malignancies Through a WISP1/BGN-Dependent Pathway. PMID:33117706
Integrated Analysis of Transcriptome and Secretome From Umbilical Cord Mesenchymal Stromal Cells Reveal New Mechanisms for the Modulation of Inflammation and Immune Activation. PMID:33117373
Contrasting signatures of genomic divergence during sympatric speciation. PMID:33116308
RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis. PMID:33116296
High-depth African genomes inform human migration and health. PMID:33116287
Genetic Determinants of Resistance to Extended-Spectrum Cephalosporin and Fluoroquinolone in Escherichia coli Isolated from Diseased Pigs in the United States. PMID:33115839
CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniae. PMID:33113377
Integrator-Dependent and Allosteric/Intrinsic Mechanisms Ensure Efficient Termination of snRNA Transcription. PMID:33113359
Widespread Transcriptional Readthrough Caused by Nab2 Depletion Leads to Chimeric Transcripts with Retained Introns. PMID:33113357
Pairwise Stimulations of Pathogen-Sensing Pathways Predict Immune Responses to Multi-adjuvant Combinations. PMID:33113356
Search for viral agents in cerebrospinal fluid in patients with multiple sclerosis using real-time PCR and metagenomics. PMID:33112911
Population genomics reveals the expansion of highly inbred Plasmodium vivax lineages in the main malaria hotspot of Brazil. PMID:33112884
Recurrent evolution of high virulence in isolated populations of a DNA virus. PMID:33112738
Asymmetric chromosome segregation and cell division in DNA damage-induced bacterial filaments. PMID:33112716
LncRBase V.2: an updated resource for multispecies lncRNAs and ClinicLSNP hosting genetic variants in lncRNAs for cancer patients. PMID:33112702
Preparation and Analysis of GLOE-Seq Libraries for Genome-Wide Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions. PMID:33111111
Tissue-Specific In Vivo Biotin Chromatin Immunoprecipitation with Sequencing in Zebrafish and Chicken. PMID:33111104
Generation of Sequencing Libraries for Structural Analysis of Bacterial 5' UTRs. PMID:33111092
Experimental adaptation of dengue virus 1 to Aedes albopictus mosquitoes by in vivo selection. PMID:33110109
A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice. PMID:33110103
Identification of potential causal variants for premature ovarian failure by whole exome sequencing. PMID:33109206
Genetic analyses of a large cohort of infertile patients with globozoospermia, DPY19L2 still the main actor, GGN confirmed as a guest player. PMID:33108537
Genetic loci underlying quantitative resistance to necrotrophic pathogens Sclerotinia and Diaporthe (Phomopsis), and correlated resistance to both pathogens. PMID:33106896
Quantifying acquisition and transmission of Enterococcus faecium using genomic surveillance. PMID:33106672
Single-cell patterning and axis characterization in the murine and human definitive endoderm. PMID:33106598
A genomic and historical synthesis of plague in 18th century Eurasia. PMID:33106412
Best practices for variant calling in clinical sequencing. PMID:33106175
Mandibulofacial Dysostosis Attributed to a Recessive Mutation of CYP26C1 in Hereford Cattle. PMID:33105751
Seasonal Regime Shift in the Viral Communities of a Permafrost Thaw Lake. PMID:33105728
REDIportal: millions of novel A-to-I RNA editing events from thousands of RNAseq experiments. PMID:33104797
Effector prediction and characterization in the oomycete pathogen Bremia lactucae reveal host-recognized WY domain proteins that lack the canonical RXLR motif. PMID:33104763
A mutation in C. neoformans mitochondrial NADH dehydrogenase results in increased virulence in mice. PMID:33103620
The whole genome sequence data analyses of a Mycobacterium tuberculosis strain SBH321 isolated in Sabah, Malaysia, belongs to Ural family of Lineage 4. PMID:33102655
Integrated Transcriptome and Histone Modification Analysis Reveals NDV Infection Under Heat Stress Affects Bursa Development and Proliferation in Susceptible Chicken Line. PMID:33101389
Improved Human Age Prediction by Using Gene Expression Profiles From Multiple Tissues. PMID:33101366
Haplotype Block Analysis Reveals Candidate Genes and QTLs for Meat Quality and Disease Resistance in Chinese Jiangquhai Pig Breed. PMID:33101353
Spike-Stalk Injection Method Causes Extensive Phenotypic and Genotypic Variations for Rice Germplasm. PMID:33101344
Comparative Evolutionary Patterns of Burkholderia cenocepacia and B. multivorans During Chronic Co-infection of a Cystic Fibrosis Patient Lung. PMID:33101250
Temperature Restriction in Entomopathogenic Bacteria. PMID:33101227
Pronghorn population genomics show connectivity in the core of their range. PMID:33100929
μDamID: A Microfluidic Approach for Joint Imaging and Sequencing of Protein-DNA Interactions in Single Cells. PMID:33099405
Calculating the most likely intron splicing orders in S. pombe, fruit fly, Arabidopsis thaliana, and humans. PMID:33099301
Genomic and Transcriptomic Analyses of Bioluminescence Genes in the Enope Squid Watasenia scintillans. PMID:33098466
Comparing rates of introgression in parasitic feather lice with differing dispersal capabilities. PMID:33097824
Single molecule, near full-length genome sequencing of dengue virus. PMID:33097792
Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells. PMID:33097661
Assessing the Genomic Variability of Gardnerella vaginalis through Comparative Genomic Analyses: Evolutionary and Ecological Implications. PMID:33097505
Noninvasive prenatal paternity determination using microhaplotypes: a pilot study. PMID:33097049
QTL mapping for soybean (Glycine max L.) leaf chlorophyll-content traits in a genotyped RIL population by using RAD-seq based high-density linkage map. PMID:33096992
A small secreted protein from Zymoseptoria tritici interacts with a wheat E3 ubiquitin ligase to promote disease. PMID:33095257
Widespread Recombination Suppression Facilitates Plant Sex Chromosome Evolution. PMID:33095227
Genome streamlining in a minute herbivore that manipulates its host plant. PMID:33095158
Powassan Virus Neuropathology and Genomic Diversity in Patients With Fatal Encephalitis. PMID:33094116
Identification of Signatures of Selection by Whole-Genome Resequencing of a Chinese Native Pig. PMID:33093844
Higher genome mutation rates of Beijing lineage of Mycobacterium tuberculosis during human infection. PMID:33093577
Genetic control of tracheid properties in Norway spruce wood. PMID:33093525
The influence of anthropogenic habitat fragmentation on the genetic structure and diversity of the malaria vector Anopheles cruzii (Diptera: Culicidae). PMID:33093465
Slow Growth and Increased Spontaneous Mutation Frequency in Respiratory Deficient afo1 - Yeast Suppressed by a Dominant Mutation in ATP3. PMID:33093184
Sequencing identifies multiple early introductions of SARS-CoV-2 to the New York City region. PMID:33093069
Draft Whole-Genome Sequence of the Anthracene-Degrading Strain Mycolicibacterium frederiksbergense LB501T, Isolated from a Polycyclic Aromatic Hydrocarbon-Contaminated Soil. PMID:33093053
Coding-Complete Genome Sequences of 23 SARS-CoV-2 Samples from the Philippines. PMID:33093050
Metagenomic Insight into Environmentally Challenged Methane-Fed Microbial Communities. PMID:33092280
Cell-Cycle-Dependent ERK Signaling Dynamics Direct Fate Specification in the Mammalian Preimplantation Embryo. PMID:33091369
RNA sequencing of whole blood in dogs with primary immune-mediated hemolytic anemia (IMHA) reveals novel insights into disease pathogenesis. PMID:33091028
A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism. PMID:33090996
Adaptation, ancestral variation and gene flow in a 'Sky Island' Drosophila species. PMID:33089581
Conflicting phylogenetic signals in plastomes of the tribe Laureae (Lauraceae). PMID:33088627
Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency. PMID:33087935
Reference exome data for a Northern Brazilian population. PMID:33087711
Liquid drop of DNA libraries reveals total genome information. PMID:33087570
Down-regulation of Beclin1 promotes direct cardiac reprogramming. PMID:33087505
Mycobacteria excise DNA damage in 12- or 13-nucleotide-long oligomers by prokaryotic-type dual incisions and performs transcription-coupled repair. PMID:33087442
Electronic DNA Analysis of CSF Cell-free Tumor DNA to Quantify Multi-gene Molecular Response in Pediatric High-grade Glioma. PMID:33087334
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma. PMID:33086062
A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans. PMID:33086057
A Cautionary Note on the Use of Genotype Callers in Phylogenomics. PMID:33084875
A whole-genome worldwide molecular epidemiology approach for contagious caprine pleuropneumonia. PMID:33083610
Mitochondrial genomes of twelve species of hyperdiverse Trigonopterus weevils. PMID:33083123
Genomic testing in 1019 individuals from 349 Pakistani families results in high diagnostic yield and clinical utility. PMID:33083013
The genome of Chinese flowering cherry (Cerasus serrulata) provides new insights into Cerasus species. PMID:33082971
Genomic analysis reveals the genetic diversity, population structure, evolutionary history and relationships of Chinese pepper. PMID:33082965
Porcine circovirus 2 (PCV2) population study in experimentally infected pigs developing PCV2-systemic disease or a subclinical infection. PMID:33082419
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity. PMID:33082293
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases. PMID:33082228
Incipient sympatric speciation in wild barley caused by geological-edaphic divergence. PMID:33082129
SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics. PMID:33081815
Comparative Study of Pine Reference Genomes Reveals Transposable Element Interconnected Gene Networks. PMID:33081418
Use of Targeted Amplicon Sequencing in Peanut to Generate Allele Information on Allotetraploid Sub-Genomes. PMID:33080972
Comparative genomics reveals the in planta-secreted Verticillium dahliae Av2 effector protein recognized in tomato plants that carry the V2 resistance locus. PMID:33078534
Regulation of single-cell genome organization into TADs and chromatin nanodomains. PMID:33077913
Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients. PMID:33077847
Pearl millet genomic vulnerability to climate change in West Africa highlights the need for regional collaboration. PMID:33077747
Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA. PMID:33077732
Ancient genomes reveal tropical bovid species in the Tibetan Plateau contributed to the prevalence of hunting game until the late Neolithic. PMID:33077602
SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity. PMID:33075803
Selection and hybridization shaped the rapid spread of African honey bee ancestry in the Americas. PMID:33075065
Functional genomics reveals the toxin-antitoxin repertoire and AbiE activity in Serratia. PMID:33074086
Genome sequencing data for wild and cultivated bananas, plantains and abacá. PMID:33072825
The Endometrial Transcription Landscape of MRKH Syndrome. PMID:33072755
Cultivation of Clear Cell Renal Cell Carcinoma Patient-Derived Organoids in an Air-Liquid Interface System as a Tool for Studying Individualized Therapy. PMID:33072556
Association of genetic and climatic variability in giant sequoia, Sequoiadendron giganteum, reveals signatures of local adaptation along moisture-related gradients. PMID:33072284
Species complex diversification by host plant use in an herbivorous insect: The source of Puerto Rican cactus mealybug pest and implications for biological control. PMID:33072273
Genetic evaluation of migratory fish: Implications for conservation and stocking programs. PMID:33072261
Whole-genome sequencing of Tarim red deer (Cervus elaphus yarkandensis) reveals demographic history and adaptations to an arid-desert environment. PMID:33072165
Mutagenesis of Puccinia graminis f. sp. tritici and Selection of Gain-of-Virulence Mutants. PMID:33072145
Analysis of DNA variants in miRNAs and miRNA 3'UTR binding sites in female infertility patients. PMID:33070169
Sperm histone H3 lysine 4 trimethylation is altered in a genetic mouse model of transgenerational epigenetic inheritance. PMID:33068438
Population genomics in two cave-obligate invertebrates confirms extremely limited dispersal between caves. PMID:33067497
Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ. PMID:33067475
Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity. PMID:33067454
Large scale genome reconstructions illuminate Wolbachia evolution. PMID:33067437
Molecular Epidemiology of Escherichia coli Producing CTX-M and pAmpC β-Lactamases from Dairy Farms Identifies a Dominant Plasmid Encoding CTX-M-32 but No Evidence for Transmission to Humans in the Same Geographical Region. PMID:33067197
CTEN Induces Tumour Cell Invasion and Survival and Is Prognostic in Radiotherapy-Treated Head and Neck Cancer. PMID:33066224
Biological effects of inhaled hydraulic fracturing sand dust. V. Pulmonary inflammatory, cytotoxic and oxidant effects. PMID:33065154
Genomic Adaptations and Evolutionary History of the Extinct Scimitar-Toothed Cat, Homotherium latidens. PMID:33065008
Three Phases of Ancient Migration Shaped the Ancestry of Human Populations in Vanuatu. PMID:33065004
Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function. PMID:33064774
The NS1 protein of the parvovirus MVM Aids in the localization of the viral genome to cellular sites of DNA damage. PMID:33064772
Evaluation of 16S rRNA Hypervariable Regions for Bioweapon Species Detection by Massively Parallel Sequencing. PMID:33061983
Transcriptome analysis of alternative splicing in the pathogen life cycle in human foreskin fibroblasts infected with Trypanosoma cruzi. PMID:33060827
Rapid genomic characterization of SARS-CoV-2 viruses from clinical specimens using nanopore sequencing. PMID:33060796
Identification of epigenetic variation associated with synchronous pod maturity in mungbean (Vigna radiata L.). PMID:33060755
MIR2111-5 locus and shoot-accumulated mature miR2111 systemically enhance nodulation depending on HAR1 in Lotus japonicus. PMID:33060582
Draft Genome Sequences of Three Fusarium oxysporum f. sp. niveum Isolates Used in Designing Markers for Race Differentiation. PMID:33060278
Active retrotransposons help maintain pericentromeric heterochromatin required for faithful cell division. PMID:33060173
Accuracy and reproducibility of somatic point mutation calling in clinical-type targeted sequencing data. PMID:33059707
Non-invasive detection of biliary tract cancer by low-coverage whole genome sequencing from plasma cell-free DNA: A prospective cohort study. PMID:33059123
Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers. PMID:33057152
Petal abscission in fragrant roses is associated with large scale differential regulation of the abscission zone transcriptome. PMID:33057097
The structural variation landscape in 492 Atlantic salmon genomes. PMID:33056985
Comparative Genomics Analyses of Lifestyle Transitions at the Origin of an Invasive Fungal Pathogen in the Genus Cryphonectria. PMID:33055257
Assessing Nanopore Sequencing for Clinical Diagnostics: a Comparison of Next-Generation Sequencing (NGS) Methods for Mycobacterium tuberculosis. PMID:33055186
Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes. PMID:33054850
smORFunction: a tool for predicting functions of small open reading frames and microproteins. PMID:33054771
Metallophosphoesterase 1, a novel candidate gene in hepatocellular carcinoma malignancy and recurrence. PMID:33054568
Ongoing Coevolution of Wolbachia and a Widespread Invasive Ant, Anoplolepis gracilipes. PMID:33053771
Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies. PMID:33053333
Extrachromosomal DNA amplicons in antimalarial-resistant Plasmodium falciparum. PMID:33053232
Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots. PMID:33052904
Regulation of microRNA-221, -222, -21 and -27 in articular cartilage subjected to abnormal compressive forces. PMID:33052608
DNA and RNA editing without sequence limitation using the flap endonuclease 1 guided by hairpin DNA probes. PMID:33051689
dbGuide: a database of functionally validated guide RNAs for genome editing in human and mouse cells. PMID:33051688
The genotype-dependent phenotypic landscape of quinoa in salt tolerance and key growth traits. PMID:33051662
Manually curated and harmonised transcriptomics datasets of psoriasis and atopic dermatitis patients. PMID:33051456
Changes in Alternative Splicing in Response to Domestication and Polyploidization in Wheat. PMID:33051269
iMOKA: k-mer based software to analyze large collections of sequencing data. PMID:33050927
Identification of Candidate Genes Involved in Fruit Ripening and Crispness Retention Through Transcriptome Analyses of a 'Honeycrisp' Population. PMID:33050481
Genomic Diversity and Hotspot Mutations in 30,983 SARS-CoV-2 Genomes: Moving Toward a Universal Vaccine for the "Confined Virus"? PMID:33050463
H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2. PMID:33049227
Tumor genotype, location, and malignant potential shape the immunogenicity of primary untreated gastrointestinal stromal tumors. PMID:33048845
A powerful long metabarcoding method for the determination of complex diets from faecal analysis of the European pond turtle (Emys orbicularis, L. 1758). PMID:33047508
H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. PMID:33046905
DeepC: predicting 3D genome folding using megabase-scale transfer learning. PMID:33046896
Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans. PMID:33046887
The first reported case of the rare mitochondrial haplotype H4a1 in ancient Egypt. PMID:33046824
A de novo frameshift mutation in ZEB2 causes polledness, abnormal skull shape, small body stature and subfertility in Fleckvieh cattle. PMID:33046754
Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium. PMID:33046696
COMPOSITUM 1 contributes to the architectural simplification of barley inflorescence via meristem identity signals. PMID:33046693
TERMINAL FLOWER 1-FD complex target genes and competition with FLOWERING LOCUS T. PMID:33046692
Characterization of the TyrR Regulon in the Rhizobacterium Enterobacter ludwigii UW5 Reveals Overlap with the CpxR Envelope Stress Response. PMID:33046562
Epigenomic landscape of enhancer elements during Hydra head organizer formation. PMID:33046126
MethHaplo: combining allele-specific DNA methylation and SNPs for haplotype region identification. PMID:33045983
Micro RNA Targets in HIV Latency: Insights into Novel Layers of Latency Control. PMID:33045840
Analysis of a phase-variable restriction modification system of the human gut symbiont Bacteroides fragilis. PMID:33045731
Detection of genomic G-quadruplexes in living cells using a small artificial protein. PMID:33045726
Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication. PMID:33045725
Transcriptome analysis revealed misregulated gene expression in blastoderms of interspecific chicken and Japanese quail F1 hybrids. PMID:33044996
Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes. PMID:33044985
Experimental study of hypoxia-induced changes in gene expression in an Asian pika, Ochotona dauurica. PMID:33044983
Evolution of multiple postzygotic barriers between species of the Mimulus tilingii complex. PMID:33044006
Characterization and mitigation of fragmentation enzyme-induced dual stranded artifacts. PMID:33043294
GeTallele: A Method for Analysis of DNA and RNA Allele Frequency Distributions. PMID:33042959
Transcriptomic and Phenotypic Analysis of a spoIIE Mutant in Clostridium beijerinckii. PMID:33042064
VapC21 Toxin Contributes to Drug-Tolerance and Interacts With Non-cognate VapB32 Antitoxin in Mycobacterium tuberculosis. PMID:33042034
Transgenerational disease specific epigenetic sperm biomarkers after ancestral exposure to dioxin. PMID:33039529
A compromised specific humoral immune response against the SARS-CoV-2 receptor-binding domain is related to viral persistence and periodic shedding in the gastrointestinal tract. PMID:33037400
Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity. PMID:33037328
The reductive glycine pathway allows autotrophic growth of Desulfovibrio desulfuricans. PMID:33037220
An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility. PMID:33037201
Genome wide analysis reveals genetic divergence between Goldsinny wrasse populations. PMID:33036553
Characterization of Emerging Swine Viral Diseases through Oxford Nanopore Sequencing Using Senecavirus A as a Model. PMID:33036361
Genome-Wide Development and Validation of Cost-Effective KASP Marker Assays for Genetic Dissection of Heat Stress Tolerance in Maize. PMID:33036291
Two Homologues of the Global Regulator Csr/Rsm Redundantly Control Phaseolotoxin Biosynthesis and Virulence in the Plant Pathogen Pseudomonas amygdali pv. phaseolicola 1448A. PMID:33036191
Clinical and molecular characteristics of carbapenem non-susceptible Escherichia coli: A nationwide survey from Oman. PMID:33036018
TRiCoLOR: tandem repeat profiling using whole-genome long-read sequencing data. PMID:33034633
Interactive Web-Based Resource for Annotation of Genetic Variants Causing Hereditary Angioedema (HADA): Database Development, Implementation, and Validation. PMID:33034563
Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing. PMID:33033274
Origin and adaptation to high altitude of Tibetan semi-wild wheat. PMID:33033250
High conservation combined with high plasticity: genomics and evolution of Borrelia bavariensis. PMID:33032522
OsSYL2AA , an allele identified by gene-based association, increases style length in rice (Oryza sativa L.). PMID:33031564
Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy. PMID:33028849
Framework for quality assessment of whole genome cancer sequences. PMID:33028839
Phylogenetic and Evolutionary Analysis Reveals the Recent Dominance of Ciprofloxacin-Resistant Shigella sonnei and Local Persistence of S. flexneri Clones in India. PMID:33028681
Fine mapping of a candidate gene for cool-temperature-induced albinism in ornamental kale. PMID:33028227
A comparative analysis of chromatin accessibility in cattle, pig, and mouse tissues. PMID:33028202
A General Model to Explain Repeated Turnovers of Sex Determination in the Salicaceae. PMID:33027519
Analysis of Genomic Characteristics and Transmission Routes of Patients With Confirmed SARS-CoV-2 in Southern California During the Early Stage of the US COVID-19 Pandemic. PMID:33026453
LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma. PMID:33026191
The reuse of public datasets in the life sciences: potential risks and rewards. PMID:33024631
A high-quality chromosome-level genome assembly reveals genetics for important traits in eggplant. PMID:33024567
The Evolutionary Success of the Marine Bacterium SAR11 Analyzed through a Metagenomic Perspective. PMID:33024052
Decoding the Architecture of the Varicella-Zoster Virus Transcriptome. PMID:33024035
A genome assembly and the somatic genetic and epigenetic mutation rate in a wild long-lived perennial Populus trichocarpa. PMID:33023654
A Novel RNA Virus, Macrobrachium rosenbergii Golda Virus (MrGV), Linked to Mass Mortalities of the Larval Giant Freshwater Prawn in Bangladesh. PMID:33023199
Mesenchyme-specific loss of Dot1L histone methyltransferase leads to skeletal dysplasia phenotype in mice. PMID:33022452
Divergence and Remarkable Diversity of the Y Chromosome in Guppies. PMID:33022040
Development on Citrus medica infected with 'Candidatus Liberibacter asiaticus' has sex-specific and -nonspecific impacts on adult Diaphorina citri and its endosymbionts. PMID:33022020
Mitochondrial genomes of stick insects (Phasmatodea) and phylogenetic considerations. PMID:33021991
Genomic instability in an interspecific hybrid of the genus Saccharomyces: a matter of adaptability. PMID:33021926
The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas. PMID:33021035
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble. PMID:33020654
Genome mapping of a LYST mutation in corn snakes indicates that vertebrate chromatophore vesicles are lysosome-related organelles. PMID:33020272
An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation. PMID:33020206
Target Enrichment Enables the Discovery of lncRNAs with Somatic Mutations or Altered Expression in Paraffin-Embedded Colorectal Cancer Samples. PMID:33019720
Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson's disease patients. PMID:33017301
Treatment with Commonly Used Antiretroviral Drugs Induces a Type I/III Interferon Signature in the Gut in the Absence of HIV Infection. PMID:33015651
Host Porphobilinogen Deaminase Deficiency Confers Malaria Resistance in Plasmodium chabaudi but Not in Plasmodium berghei or Plasmodium falciparum During Intraerythrocytic Growth. PMID:33014890
Tn Antigen Expression Contributes to an Immune Suppressive Microenvironment and Drives Tumor Growth in Colorectal Cancer. PMID:33014816
Mutation accumulation and horizontal gene transfer in Escherichia coli colonizing the gut of old mice. PMID:33014261
Structural Variations Affecting Genes and Transposable Elements of Chromosome 3B in Wheats. PMID:33014014
ddRAD Sequencing-Based Identification of Genomic Boundaries and Permeability in Quercus ilex and Q. suber Hybrids. PMID:33013984
Genetic Diversity, Pedigree Relationships, and A Haplotype-Based DNA Fingerprinting System of Red Bayberry Cultivars. PMID:33013982
Validation of a Combined Transcriptome and T Cell Receptor Alpha/Beta (TRA/TRB) Repertoire Assay at the Single Cell Level for Paucicellular Samples. PMID:33013853
Complete Genome Sequencing and Transcriptome Analysis of Nitrogen Metabolism of Succinivibrio dextrinosolvens Strain Z6 Isolated From Dairy Cow Rumen. PMID:33013723
Evolutionary history of Mycobacterium leprae in the Pacific Islands. PMID:33012236
Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico. PMID:33012233
Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus. PMID:33012227
Investigating the demographic history of Japan using ancient oral microbiota. PMID:33012223
Biased Gene Retention in the Face of Introgression Obscures Species Relationships. PMID:33011798
A genetic screen for suppressors of hyper-repression of the fission yeast PHO regulon by Pol2 CTD mutation T4A implicates inositol 1-pyrophosphates as agonists of precocious lncRNA transcription termination. PMID:33010152
Chromosome-level genome assembly of Paralithodes platypus provides insights into evolution and adaptation of king crabs. PMID:33010101
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology. PMID:33009951
The Cassandra retrotransposon landscape in sugar beet (Beta vulgaris) and related Amaranthaceae: recombination and re-shuffling lead to a high structural variability. PMID:33009553
TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control. PMID:33009411
An extended KASP-SNP resource for molecular breeding in Chinese cabbage(Brassica rapa L. ssp. pekinensis). PMID:33007009
The O-GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stress. PMID:33006972
RNA-seq with RNase H-based ribosomal RNA depletion specifically designed for C. elegans. PMID:33005886
Caenorhabditis elegans dauers vary recovery in response to bacteria from natural habitat. PMID:33005351
Large inverted repeats identified by intra-specific comparison of mitochondrial genomes provide insights into the evolution of Agrocybe aegerita. PMID:33005305
Migration dynamics of an important rice pest: The brown planthopper (Nilaparvata lugens) across Asia-Insights from population genomics. PMID:33005233
Historic and modern genomes unveil a domestic introgression gradient in a wild red junglefowl population. PMID:33005225
Whole-exome sequencing reveals a long-term decline in effective population size of red spruce (Picea rubens). PMID:33005218
The Genetic Architecture of Post-Zygotic Reproductive Isolation Between Anopheles coluzzii and An. quadriannulatus. PMID:33005168
Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of blaTEM-1B. PMID:33004811
Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae. PMID:33004800
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation. PMID:33004791
Allelic Variation of MYB10 Is the Major Force Controlling Natural Variation in Skin and Flesh Color in Strawberry (Fragaria spp.) Fruit. PMID:33004617
Complete Genome Sequence of Bdellovibrio sp. Strain KM01, a Predatory Bacterium Isolated from Soil. PMID:33004449
SequelTools: a suite of tools for working with PacBio Sequel raw sequence data. PMID:33004007
Combinatorial Action of Temporally Segregated Transcription Factors. PMID:33002421
Large-scale variation in single nucleotide polymorphism density within the laboratory axolotl (Ambystoma mexicanum). PMID:33001517
Repeat expansions confer WRN dependence in microsatellite-unstable cancers. PMID:32999459
Next-generation sequencing in the diagnosis of viral encephalitis: sensitivity and clinical limitations. PMID:32999423
Direct interactions with commensal streptococci modify intercellular communication behaviors of Streptococcus mutans. PMID:32999420
Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid Cells. PMID:32999023
Genetic Control of Neonatal Immune Tolerance to an Exogenous Retrovirus. PMID:32999021
Confirmed effects of candidate variants for milk production, udder health, and udder morphology in dairy cattle. PMID:32998688
Swimming under elevated hydrostatic pressure increases glycolytic activity in gas gland cells of the European eel. PMID:32997701
Whole exome sequencing identifies rare coding variants in novel human-mouse ortholog genes in African individuals diagnosed with non-syndromic hearing impairment. PMID:32996353
Genome-wide dissection of hybridization for fiber quality- and yield-related traits in upland cotton. PMID:32996179
The application of deep learning for the classification of correct and incorrect SNP genotypes from whole-genome DNA sequencing pipelines. PMID:32996082
Fixed single-cell RNA sequencing for understanding virus infection and host response. PMID:32995793
Rapid detection of inter-clade recombination in SARS-CoV-2 with Bolotie. PMID:32995774
ReScan, a Multiplex Diagnostic Pipeline, Pans Human Sera for SARS-CoV-2 Antigens. PMID:32995758
Highly multiplexed, fast and accurate nanopore sequencing for verification of synthetic DNA constructs and sequence libraries. PMID:32995546
Harnessing endogenous repair mechanisms for targeted gene knock-in of bovine embryos. PMID:32994506
CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration. PMID:32994325
Stability of the Virome in Lab- and Field-Collected Aedes albopictus Mosquitoes across Different Developmental Stages and Possible Core Viruses in the Publicly Available Virome Data of Aedes Mosquitoes. PMID:32994288
In vitro resynthesis of lichenization reveals the genetic background of symbiosis-specific fungal-algal interaction in Usnea hakonensis. PMID:32993496
Role of SARS-CoV-2 in Altering the RNA-Binding Protein and miRNA-Directed Post-Transcriptional Regulatory Networks in Humans. PMID:32993015
Proteomics Reveals Distinct Changes Associated with Increased Gamma Radiation Resistance in the Black Yeast Exophiala dermatitidis. PMID:32992890
Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling. PMID:32992037
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. PMID:32991842
Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder. PMID:32991838
High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection. PMID:32991830
Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice. PMID:32990597
The mosaic genome of indigenous African cattle as a unique genetic resource for African pastoralism. PMID:32989325
Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism. PMID:32989157
CsrA Supports both Environmental Persistence and Host-Associated Growth of Acinetobacter baumannii. PMID:32989034
Evolutionary Dynamics of Transposable Elements Following a Shared Polyploidization Event in the Tribe Andropogoneae. PMID:32988994
Functional signatures of evolutionarily young CTCF binding sites. PMID:32988407
Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain. PMID:32986839
The Genetic Architecture of Emerging Fungicide Resistance in Populations of a Global Wheat Pathogen. PMID:32986802
Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection. PMID:32986782
A comparative study of single nucleotide variant detection performance using three massively parallel sequencing methods. PMID:32986766
Genomic characterization of a diazotrophic microbiota associated with maize aerial root mucilage. PMID:32986754
A nonsense variant in Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5) is associated with equine familial isolated hypoparathyroidism in Thoroughbred foals. PMID:32986719
Viral gene drive in herpesviruses. PMID:32985507
Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma. PMID:32985499
High quality genome of Erigeron breviscapus provides a reference for herbal plants in Asteraceae. PMID:32985109
Urine as a high-quality source of host genomic DNA from wild populations. PMID:32985084
A chromosome-scale reference genome of trifoliate orange (Poncirus trifoliata) provides insights into disease resistance, cold tolerance and genome evolution in Citrus. PMID:32985030
INCIDENTAL PULMONARY METASTASES REVEALING SUBCENTIMETER PAPILLARY THYROID CARCINOMA. PMID:32984537
Impact of Sustained Transforming Growth Factor-β Receptor Inhibition on Chromatin Accessibility and Gene Expression in Cultured Human Endometrial MSC. PMID:32984350
Phylogeographical Analysis Reveals the Historic Origin, Emergence, and Evolutionary Dynamics of Methicillin-Resistant Staphylococcus aureus ST228. PMID:32983046
Elucidating the Influence of Chromosomal Architecture on Transcriptional Regulation in Prokaryotes - Observing Strong Local Effects of Nucleoid Structure on Gene Regulation. PMID:32983020
T Cell Responses to Neural Autoantigens Are Similar in Alzheimer's Disease Patients and Age-Matched Healthy Controls. PMID:32982670
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes. PMID:32979312
Comparative analysis of chloroplast genomes in Vasconcellea pubescens A.DC. and Carica papaya L. PMID:32978465
Evolutionary dynamics of Tomato spotted wilt virus within and between alternate plant hosts and thrips. PMID:32978446
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor. PMID:32978388
Molecular correlates of cisplatin-based chemotherapy response in muscle invasive bladder cancer by integrated multi-omics analysis. PMID:32978382
GADD34 is a modulator of autophagy during starvation. PMID:32978159
UTX/KDM6A suppresses AP-1 and a gliogenesis program during neural differentiation of human pluripotent stem cells. PMID:32977832
Tracing key genes associated with the Pinctada margaritifera albino phenotype from juvenile to cultured pearl harvest stages using multiple whole transcriptome sequencing. PMID:32977773
Identification of QTLs Controlling α-Glucosidase Inhibitory Activity in Pepper (Capsicum annuum L.) Leaf and Fruit Using Genotyping-by-Sequencing Analysis. PMID:32977701
Transcriptome Sequencing Revealed an Inhibitory Mechanism of Aspergillus flavus Asexual Development and Aflatoxin Metabolism by Soy-Fermenting Non-Aflatoxigenic Aspergillus. PMID:32977505
Sex-Specific Selection Drives the Evolution of Alternative Splicing in Birds. PMID:32977339
Tobacco Smoke Exposure Exacerbated Crystalline Silica-Induced Lung Toxicity in Rats. PMID:32976597
Comprehensive Analyses of the Complete Mitochondrial Genome of Figulus binodulus (Coleoptera: Lucanidae). PMID:32976575
Genomic analysis of cardiac surgery-associated Mycobacterium chimaera infections in Italy. PMID:32976495
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism. PMID:32975579
Nuclear and mitochondrial genome sequencing of North-African Leishmania infantum isolates from cured and relapsed visceral leishmaniasis patients reveals variations correlating with geography and phenotype. PMID:32975503
Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada. PMID:32974576
Characterization of Highly Mucus-Adherent Non-GMO Derivatives of Lacticaseibacillus rhamnosus GG. PMID:32974330
High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis. PMID:32973882
Genomic Characteristics and Selection Signatures in Indigenous Chongming White Goat (Capra hircus). PMID:32973871
Changes in H3K27ac at Gene Regulatory Regions in Porcine Alveolar Macrophages Following LPS or PolyIC Exposure. PMID:32973863
Different Families of Retrotransposons and DNA Transposons Are Actively Transcribed and May Have Transposed Recently in Physcomitrium (Physcomitrella) patens. PMID:32973835
Analysis of Metabolites and Gene Expression Changes Relative to Apricot (Prunus armeniaca L.) Fruit Quality During Development and Ripening. PMID:32973833
Mapping a Partial Andromonoecy Locus in Citrullus lanatus Using BSA-Seq and GWAS Approaches. PMID:32973825
Nanopore MinION Sequencing Reveals Possible Transfer of bla KPC-2 Plasmid Across Bacterial Species in Two Healthcare Facilities. PMID:32973725
Genome-Wide Network of lncRNA-mRNA During Ovine Oocyte Development From Germinal Vesicle to Metaphase II in vitro. PMID:32973554
NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy. PMID:32973342
Burn resuscitation strategy influences the gut microbiota-liver axis in swine. PMID:32973266
Transposon expression in the Drosophila brain is driven by neighboring genes and diversifies the neural transcriptome. PMID:32973040
Identification and Characterization of Breakpoints and Mutations on Drosophila melanogaster Balancer Chromosomes. PMID:32972999
Whole-Genome Sequence of SARS-CoV-2 Isolate Siena-1/2020. PMID:32972948
Genome Sequence of Oenococcus oeni OE37, an Autochthonous Strain Isolated from an Italian White Wine. PMID:32972928
GraphAligner: rapid and versatile sequence-to-graph alignment. PMID:32972461
Immunohistochemistry and Mutation Analysis of SDHx Genes in Carotid Paragangliomas. PMID:32971818
Deciphering the SSR incidences across viral members of Coronaviridae family. PMID:32971122
Paralogs and off-target sequences improve phylogenetic resolution in a densely-sampled study of the breadfruit genus (Artocarpus, Moraceae). PMID:32970819
Existence and possible roles of independent non-CpG methylation in the mammalian brain. PMID:32970817
MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly. PMID:32969791
Genomic signatures of convergent adaptation to Alpine environments in three Brassicaceae species. PMID:32969558
Initiation of a conserved trophectoderm program in human, cow and mouse embryos. PMID:32968278
Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniae. PMID:32968015
Integrated Analysis of Gene Expression, SNP, InDel, and CNV Identifies Candidate Avirulence Genes in Australian Isolates of the Wheat Leaf Rust Pathogen Puccinia triticina. PMID:32967372
ATAC-Seq Identifies Chromatin Landscapes Linked to the Regulation of Oxidative Stress in the Human Fungal Pathogen Candida albicans. PMID:32967096
Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication. PMID:32966791
Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome. PMID:32966779
Chromosome-Scale Genome Assemblies of Aphids Reveal Extensively Rearranged Autosomes and Long-Term Conservation of the X Chromosome. PMID:32966576
Germline and somatic albinism variants in amelanotic/hypomelanotic melanoma: Increased carriage of TYR and OCA2 variants. PMID:32966289
Construction of a chromosome-scale long-read reference genome assembly for potato. PMID:32964225
The Complete Chloroplast Genome of Arabidopsis thaliana Isolated in Korea (Brassicaceae): An Investigation of Intraspecific Variations of the Chloroplast Genome of Korean A. thaliana. PMID:32964010
Resequencing of 1,143 indica rice accessions reveals important genetic variations and different heterosis patterns. PMID:32963241
CRISpy-Pop: A Web Tool for Designing CRISPR/Cas9-Driven Genetic Modifications in Diverse Populations. PMID:32963084
Intergenerational Pathogen-Induced Diapause in Caenorhabditis elegans Is Modulated by mir-243. PMID:32963007
Theoretical characterisation of strand cross-correlation in ChIP-seq. PMID:32962634
Differential Gene Expression with an Emphasis on Floral Organ Size Differences in Natural and Synthetic Polyploids of Nicotiana tabacum (Solanaceae). PMID:32961813
NCBP3 positively impacts mRNA biogenesis. PMID:32960271
The methylation landscape and its role in domestication and gene regulation in the chicken. PMID:32958860
Telomere dysfunction activates YAP1 to drive tissue inflammation. PMID:32958778
Visual mate preference evolution during butterfly speciation is linked to neural processing genes. PMID:32958765
Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication. PMID:32958756
Ecological divergence and hybridization of Neotropical Leishmania parasites. PMID:32958676
PacBio genome sequencing reveals new insights into the genomic organisation of the multi-copy ToxB gene of the wheat fungal pathogen Pyrenophora tritici-repentis. PMID:32957933
SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol. PMID:32957927
Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide in Cryptococcus neoformans. PMID:32956370
Comparative transcriptome analysis uncovers different heat stress responses in heat-resistant and heat-sensitive jujube cultivars. PMID:32956359
Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments. PMID:32956035
Long-term expansion with germline potential of human primordial germ cell-like cells in vitro. PMID:32954504
UMI-Gen: A UMI-based read simulator for variant calling evaluation in paired-end sequencing NGS libraries. PMID:32952940
Haplotype threading: accurate polyploid phasing from long reads. PMID:32951599
A novel negevirus isolated from Aedes vexans mosquitoes in Finland. PMID:32951134
Identification of novel fusion transcripts in meningioma. PMID:32949309
Mutation profiling in eight cases of vagal paragangliomas. PMID:32948195
Limitations of Detecting Genetic Variants from the RNA Sequencing Data in Tissue and Fine-Needle Aspiration Samples. PMID:32948110
Long-read only assembly of Drechmeria coniospora genomes reveals widespread chromosome plasticity and illustrates the limitations of current nanopore methods. PMID:32947622
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development. PMID:32946788
Generalizability of "GWAS Hits" in Clinical Populations: Lessons from Childhood Cancer Survivors. PMID:32946765
Genomic analyses of diverse wild and cultivated accessions provide insights into the evolutionary history of jujube. PMID:32946650
Disentangling primer interactions improves SARS-CoV-2 genome sequencing by multiplex tiling PCR. PMID:32946527
Expanded genome-wide comparisons give novel insights into population structure and genetic heterogeneity of Leishmania tropica complex. PMID:32946436
Developmental stage-specific A-to-I editing pattern in the postnatal pineal gland of pigs (Sus scrofa). PMID:32944232
Chikungunya virus infections in Finnish travellers 2009-2019. PMID:32944165
A novel WD40-repeat protein involved in formation of epidermal bladder cells in the halophyte quinoa. PMID:32943738
Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation. PMID:32943640
Removing reference bias and improving indel calling in ancient DNA data analysis by mapping to a sequence variation graph. PMID:32943086
A de novo synonymous variant in EFTUD2 disrupts normal splicing and causes mandibulofacial dysostosis with microcephaly: case report. PMID:32943010
Meiotic recombination in the offspring of Microbotryum hybrids and its impact on pathogenicity. PMID:32942986
Changes in Nuclear Shape and Gene Expression in Response to Simulated Microgravity Are LINC Complex-Dependent. PMID:32942630
Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications. PMID:32941995
The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae. PMID:32941642
Different Sources of Allelic Variation Drove Repeated Color Pattern Divergence in Cichlid Fishes. PMID:32941629
The qBED track: a novel genome browser visualization for point processes. PMID:32941613
Studies of rice Hd1 haplotypes worldwide reveal adaptation of flowering time to different environments. PMID:32941524
In silico tools for accurate HLA and KIR inference from clinical sequencing data empower immunogenetics on individual-patient and population scales. PMID:32940337
Scanning window analysis of non-coding regions within normal-tumor whole-genome sequence samples. PMID:32940334
Systematic analysis of bypass suppression of essential genes. PMID:32939983
Whole-Genome Sequencing of Inbred Mouse Strains Selected for High and Low Open-Field Activity. PMID:32939625
Metagenome datasets from women with polycystic ovary syndrome from Irkutsk, Eastern Siberia, Russia. PMID:32939371
Microbial dark matter filling the niche in hypersaline microbial mats. PMID:32938503
Genome resequencing data for Iranian local dogs and wolves. PMID:32938490
Multi-model seascape genomics identifies distinct environmental drivers of selection among sympatric marine species. PMID:32938400
Transcriptome profiling at osmotic and ionic phases of salt stress response in bread wheat uncovers trait-specific candidate genes. PMID:32938380
Long-read sequencing and de novo genome assembly of marine medaka (Oryzias melastigma). PMID:32938378
Discovery of a Novel Induced Polymorphism in SD1 Gene Governing Semi-Dwarfism in Rice and Development of a Functional Marker for Marker-Assisted Selection. PMID:32937792
A Survey of Rare Epigenetic Variation in 23,116 Human Genomes Identifies Disease-Relevant Epivariations and CGG Expansions. PMID:32937144
PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway. PMID:32937136
Adipocyte Reprogramming by the Transcriptional Coregulator GPS2 Impacts Beta Cell Insulin Secretion. PMID:32937117
Identifying the causes and consequences of assembly gaps using a multiplatform genome assembly of a bird-of-paradise. PMID:32937018
Discovering functional sequences with RELICS, an analysis method for CRISPR screens. PMID:32936799
Experimental evolution reveals nitrate tolerance mechanisms in Desulfovibrio vulgaris. PMID:32934357
Genomic profiling of bacterial and fungal communities and their predictive functionality during pulque fermentation by whole-genome shotgun sequencing. PMID:32934253
Entamoeba and Giardia parasites implicated as hosts of CRESS viruses. PMID:32934242
CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells. PMID:32934219
Sterol regulatory element-binding protein Sre1 regulates carotenogenesis in the red yeast Xanthophyllomyces dendrorhous. PMID:32933952
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. PMID:32933554
Molecular basis of a new ovine model for human 3M syndrome-2. PMID:32933480
Unraveling the Genetic Basis for the Rapid Diversification of Male Genitalia between Drosophila Species. PMID:32931587
The Genomic Basis of Rapid Adaptation to Antibiotic Combination Therapy in Pseudomonas aeruginosa. PMID:32931584
The immunity of Meiwa kumquat against Xanthomonas citri is associated with a known susceptibility gene induced by a transcription activator-like effector. PMID:32931525
Bridging the membrane lipid divide: bacteria of the FCB group superphylum have the potential to synthesize archaeal ether lipids. PMID:32929208
The mutational landscape of histiocytic sarcoma associated with lymphoid malignancy. PMID:32929178
Evolved Differences in cis and trans Regulation Between the Maternal and Zygotic mRNA Complements in the Drosophila Embryo. PMID:32928902
De novo mutations of SCN1A are responsible for arthrogryposis broadening the SCN1A-related phenotypes. PMID:32928894
The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA. PMID:32926445
Managing a Large-Scale Multiomics Project: A Team Science Case Study in Proteogenomics. PMID:32926368
Statistical and Bioinformatics Analysis of Data from Bulk and Single-Cell RNA Sequencing Experiments. PMID:32926366
Dioecy Is Associated with High Genetic Diversity and Adaptation Rates in the Plant Genus Silene. PMID:32926156
DNA polymerase α interacts with H3-H4 and facilitates the transfer of parental histones to lagging strands. PMID:32923642
Are Antisense Proteins in Prokaryotes Functional? PMID:32923454
Unraveling the Spiraling Radiation: A Phylogenomic Analysis of Neotropical Costus L. PMID:32922414
Diversity analysis of 80,000 wheat accessions reveals consequences and opportunities of selection footprints. PMID:32917907
Hyperacetylated chromatin domains mark cell type-specific genes and suggest distinct modes of enhancer function. PMID:32917861
Genome-wide detection of signatures of selection in indicine and Brazilian locally adapted taurine cattle breeds using whole-genome re-sequencing data. PMID:32917133
TIP_finder: An HPC Software to Detect Transposable Element Insertion Polymorphisms in Large Genomic Datasets. PMID:32917036
Incubation with a Complex Orange Essential Oil Leads to Evolved Mutants with Increased Resistance and Tolerance. PMID:32916977
Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle. PMID:32916091
A novel algorithm comprehensively characterizes human RH genes using whole-genome sequencing data. PMID:32915977
Association between brown eye colour in rs12913832:GG individuals and SNPs in TYR, TYRP1, and SLC24A4. PMID:32915910
APOL1 polymorphism modulates sphingolipid profile of human podocytes. PMID:32915357
Large domains of heterochromatin direct the formation of short mitotic chromosome loops. PMID:32915140
Multiplex Gene Profiling of Cell-Free DNA in Patients With Metastatic Melanoma for Monitoring Disease. PMID:32913981
Single-cell transcriptomic atlas of primate cardiopulmonary aging. PMID:32913304
Direct identification of a mutation in OsSh1 causing non-shattering in a rice (Oryza sativa L.) mutant cultivar using whole-genome resequencing. PMID:32913300
Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. PMID:32913280
A mutation in the intron splice acceptor site of a GA3ox gene confers dwarf architecture in watermelon (Citrullus lanatus L.). PMID:32913219
Chromonomer: A Tool Set for Repairing and Enhancing Assembled Genomes Through Integration of Genetic Maps and Conserved Synteny. PMID:32912931
Using genomic resources for linkage analysis in Peromyscus with an application for characterizing Dominant Spot. PMID:32912160
A comparison of BeadChip and WGS genotyping outputs using partial validation by sanger sequencing. PMID:32912136
Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells. PMID:32911681
The MIR137 VNTR rs58335419 Is Associated With Cognitive Impairment in Schizophrenia and Altered Cortical Morphology. PMID:32910167
Comparison of genomic diversity and structure of sable antelope (Hippotragus niger) in zoos, conservation centers, and private ranches in North America. PMID:32908610
Seascape genomics as a new tool to empower coral reef conservation strategies: An example on north-western Pacific Acropora digitifera. PMID:32908595
Fine-scale seascape genomics of an exploited marine species, the common cockle Cerastoderma edule, using a multimodelling approach. PMID:32908590
Epigenetic gene silencing by heterochromatin primes fungal resistance. PMID:32908306
IonCRAM: a reference-based compression tool for ion torrent sequence files. PMID:32907531
Cytogenetically visible inversions are formed by multiple molecular mechanisms. PMID:32906200
Epigenome-wide association study for transgenerational disease sperm epimutation biomarkers following ancestral exposure to jet fuel hydrocarbons. PMID:32905848
Modulating Isoprenoid Biosynthesis Increases Lipooligosaccharides and Restores Acinetobacter baumannii Resistance to Host and Antibiotic Stress. PMID:32905776
INO80C Remodeler Maintains Genomic Stability by Preventing Promiscuous Transcription at Replication Origins. PMID:32905765
iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy. PMID:32905764
Transcriptome dataset from bark and latex tissues of three Hevea brasiliensis clones. PMID:32904357
Combining a New Exome Capture Panel With an Effective varBScore Algorithm Accelerates BSA-Based Gene Cloning in Wheat. PMID:32903549
Homogeneity among glyphosate-resistant Amaranthus palmeri in geographically distant locations. PMID:32903277
Diagnostic yield and clinical utility of whole exome sequencing using an automated variant prioritization system, EVIDENCE. PMID:32901917
RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk. PMID:32901120
Fonio millet genome unlocks African orphan crop diversity for agriculture in a changing climate. PMID:32901040
FastClone is a probabilistic tool for deconvoluting tumor heterogeneity in bulk-sequencing samples. PMID:32901013
p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo. PMID:32900967
Network Rewiring: Physiological Consequences of Reciprocally Exchanging the Physical Locations and Growth-Phase-Dependent Expression Patterns of the Salmonella fis and dps Genes. PMID:32900812
Repetitive Elements Contribute to the Diversity and Evolution of Centromeres in the Fungal Genus Verticillium. PMID:32900804
Aneuploidy-induced proteotoxic stress can be effectively tolerated without dosage compensation, genetic mutations, or stress responses. PMID:32900371
The Transcriptomic Landscape of Cupriavidus metallidurans CH34 Acutely Exposed to Copper. PMID:32899882
Newly Emerged Serotype 1c of Shigella flexneri: Multiple Origins and Changing Drug Resistance Landscape. PMID:32899396
Ecological Load and Balancing Selection in Circumboreal Barnacles. PMID:32898261
Myxosporea (Myxozoa, Cnidaria) Lack DNA Cytosine Methylation. PMID:32898240
Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication. PMID:32897188
Genomic epidemiology of emerging ESBL-producing Salmonella Kentucky bla CTX-M-14b in Europe. PMID:32896234
RnhP is a plasmid-borne RNase HI that contributes to genome maintenance in the ancestral strain Bacillus subtilis NCIB 3610. PMID:32896031
Microbial interactions in the mosquito gut determine Serratia colonization and blood-feeding propensity. PMID:32895494
lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation. PMID:32895492
Population sequencing enhances understanding of tea plant evolution. PMID:32895382
Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network. PMID:32894225
Variation around the dominant viral genome sequence contributes to viral load and outcome in patients with Ebola virus disease. PMID:32894206
The wild grape genome sequence provides insights into the transition from dioecy to hermaphroditism during grape domestication. PMID:32892750
Impact of DNA extraction on whole genome sequencing analysis for characterization and relatedness of Shiga toxin-producing Escherichia coli isolates. PMID:32887913
Resolution of polycistronic RNA by SL2 trans-splicing is a widely conserved nematode trait. PMID:32887788
Mutant and Recombinant Phages Selected from In Vitro Coevolution Conditions Overcome Phage-Resistant Listeria monocytogenes. PMID:32887717
CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade. PMID:32887696
Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms. PMID:32887688
Long-read sequencing for non-small-cell lung cancer genomes. PMID:32887687
Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing. PMID:32887686
Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank. PMID:32887585
Identification of a Novel Variant in EARS2 Associated with a Severe Clinical Phenotype Expands the Clinical Spectrum of LTBL. PMID:32887222
Introduction of Mycobacterium ulcerans disease in the Bankim Health District of Cameroon follows damming of the Mapé River. PMID:32886658
Systematic screening of CTCF binding partners identifies that BHLHE40 regulates CTCF genome-wide distribution and long-range chromatin interactions. PMID:32885250
EXFI: Exon and splice graph prediction without a reference genome. PMID:32884664
CRISPR-Cas9 enrichment and long read sequencing for fine mapping in plants. PMID:32884578
Dissecting the epigenomic dynamics of human fetal germ cell development at single-cell resolution. PMID:32884136
Yersinia pestis strains from Latvia show depletion of the pla virulence gene at the end of the second plague pandemic. PMID:32884081
Towards personalized induction therapy for esophageal adenocarcinoma: organoids derived from endoscopic biopsy recapitulate the pre-treatment tumor. PMID:32884042
Genome diversity of Chinese indigenous chicken and the selective signatures in Chinese gamecock chicken. PMID:32883984
Genome-Wide Identification of Transcription Start Sites in Two Alphaproteobacteria, Rhodobacter sphaeroides 2.4.1 and Novosphingobium aromaticivorans DSM 12444. PMID:32883797
Complete Genome Sequence of Nitrogen-Fixing Paenibacillus sp. Strain URB8-2, Isolated from the Rhizosphere of Wild Grass. PMID:32883790
The Nubeam reference-free approach to analyze metagenomic sequencing reads. PMID:32883749
Deep Convergence, Shared Ancestry, and Evolutionary Novelty in the Genetic Architecture of Heliconius Mimicry. PMID:32883703
1200 high-quality metagenome-assembled genomes from the rumen of African cattle and their relevance in the context of sub-optimal feeding. PMID:32883364
Systematic analysis reveals cis and trans determinants affecting C-to-U RNA editing in Arabidopsis thaliana. PMID:32883207
Nucleotide diversity of functionally different groups of immune response genes in Old World camels based on newly annotated and reference-guided assemblies. PMID:32883205
Analysis of Whole Genome Resequencing Datasets from a Worldwide Sample of Sheep Breeds to Identify Potential Causal Mutations Influencing Milk Composition Traits. PMID:32882861
Characterizing allele- and haplotype-specific copy numbers in single cells with CHISEL. PMID:32879467
Twentieth-century emergence of antimicrobial resistant human- and bovine-associated Salmonella enterica serotype Typhimurium lineages in New York State. PMID:32879348
Sex-biased patterns shaped the genetic history of Roma. PMID:32879340
Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis. PMID:32879318
Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations. PMID:32879310
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components. PMID:32878980
Pooled analysis of radiation hybrids identifies loci for growth and drug action in mammalian cells. PMID:32878976
Digging into the Genomic Past of Swiss Honey Bees by Whole-Genome Sequencing Museum Specimens. PMID:32877519
Genomic insight into the developmental history of southern highbush blueberry populations. PMID:32873965
Analysis of muntjac deer genome and chromatin architecture reveals rapid karyotype evolution. PMID:32873878
Currently favored sampling practices for tumor sequencing can produce optimal results in the clinical setting. PMID:32873813
AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications. PMID:32873787
A Novel Mycovirus Evokes Transcriptional Rewiring in the Fungus Malassezia and Stimulates Beta Interferon Production in Macrophages. PMID:32873760
Dynamic PB2-E627K substitution of influenza H7N9 virus indicates the in vivo genetic tuning and rapid host adaptation. PMID:32873642
High precision Neisseria gonorrhoeae variant and antimicrobial resistance calling from metagenomic Nanopore sequencing. PMID:32873606
RNA G-quadruplex structures exist and function in vivo in plants. PMID:32873317
Mapping QTL Associated with Resistance to Avian Oncogenic Marek's Disease Virus (MDV) Reveals Major Candidate Genes and Variants. PMID:32872585
A Model for the Production of Regulatory Grade Viral Hemorrhagic Fever Exposure Stocks: From Field Surveillance to Advanced Characterization of SFTSV. PMID:32872451
Structure and Sequence of the Sex Determining Locus in Two Wild Populations of Nile Tilapia. PMID:32872430
A Functional ClpXP Protease is Required for Induction of the Accessory Toxin Genes, tst, sed, and sec. PMID:32872362
OGRE: Overlap Graph-based metagenomic Read clustEring. PMID:32871010
Embryo-Like Features in Developing Bacillus subtilis Biofilms. PMID:32871001
Intra-species differences in population size shape life history and genome evolution. PMID:32869739
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis. PMID:32869021
Alteration of genome folding via contact domain boundary insertion. PMID:32868908
Seasonal plasticity and diel stability of H3K27me3 in natural fluctuating environments. PMID:32868888
Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site. PMID:32868871
Meta-analysis of GWAS in canola blackleg (Leptosphaeria maculans) disease traits demonstrates increased power from imputed whole-genome sequence. PMID:32868838
Exploring the genetic basis of fatty liver development in geese. PMID:32868783
Supergene evolution via stepwise duplications and neofunctionalization of a floral-organ identity gene. PMID:32868445
Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients. PMID:32868333
Dalbavancin exposure in vitro selects for dalbavancin-non-susceptible and vancomycin-intermediate strains of methicillin-resistant Staphylococcus aureus. PMID:32866650
Comprehensive evolution and molecular characteristics of a large number of SARS-CoV-2 genomes reveal its epidemic trends. PMID:32866640
An integrative proteogenomics approach reveals peptides encoded by annotated lincRNA in the mouse kidney inner medulla. PMID:32866085
Somatic mutations in colorectal cancer are associated with the epigenetic modifications. PMID:32865336
In silico identification of pseudo-exon activation events in personal genome and transcriptome data. PMID:32865117
Evaluation of computational methods for human microbiome analysis using simulated data. PMID:32864214
Multi-omics analysis to examine microbiota, host gene expression and metabolites in the intestine of black tiger shrimp (Penaeus monodon) with different growth performance. PMID:32864208
Impact of investigational microbiota therapeutic RBX2660 on the gut microbiome and resistome revealed by a placebo-controlled clinical trial. PMID:32862830
Circular ANRIL isoforms switch from repressors to activators of p15/CDKN2B expression during RAF1 oncogene-induced senescence. PMID:32862732
A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis. PMID:32859762
Genome-Wide Detection of Selection Signatures in Duroc Revealed Candidate Genes Relating to Growth and Meat Quality. PMID:32859686
Low pathogenic avian influenza virus isolates with different levels of defective genome segments vary in pathogenicity and transmission efficiency. PMID:32859269
Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference. PMID:32859263
Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies Analysis. PMID:32858978
Comparative Transcriptome Analysis of Pine Trees Treated with Resistance-Inducing Substances against the Nematode Bursaphelenchus xylophilus. PMID:32858932
Multivalent Proteins Rapidly and Reversibly Phase-Separate upon Osmotic Cell Volume Change. PMID:32857953
The conserved ribonuclease aCPSF1 triggers genome-wide transcription termination of Archaea via a 3'-end cleavage mode. PMID:32857850
Whole genome sequencing analysis of high confidence variants of B-cell lymphoma in Canis familiaris. PMID:32857815
Systemic Mesenchymal Stem Cell Treatment Mitigates Structural and Functional Retinal Ganglion Cell Degeneration in a Mouse Model of Multiple Sclerosis. PMID:32855863
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma. PMID:32855532
Complete Genome Sequence of "Candidatus Phytoplasma asteris" RP166, a Plant Pathogen Associated with Rapeseed Phyllody Disease in Poland. PMID:32855252
Two Metagenome-Assembled Genome Sequences of Magnetotactic Bacteria in the Order Magnetococcales. PMID:32855242
Complete Genome Assemblies of the Rare Salmonella enterica Serovar Adjame Using Nanopore and Illumina Sequence Reads. PMID:32855241
Exploring the Regulatory Potential of Long Non-Coding RNA in Feed Efficiency of Indicine Cattle. PMID:32854445
Improved Reference Genome Uncovers Novel Sex-Linked Regions in the Guppy (Poecilia reticulata). PMID:32853348
Classification of Takifugu rubripes, T. chinensis and T. pseudommus by genotyping-by-sequencing. PMID:32853203
Insights into Ammonia Adaptation and Methanogenic Precursor Oxidation by Genome-Centric Analysis. PMID:32852203
A broad mutational target explains a fast rate of phenotypic evolution. PMID:32851977
Altered 3D chromatin structure permits inversional recombination at the IgH locus. PMID:32851160
regSNPs-ASB: A Computational Framework for Identifying Allele-Specific Transcription Factor Binding From ATAC-seq Data. PMID:32850739
Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer. PMID:32850431
DINTD: Detection and Inference of Tandem Duplications From Short Sequencing Reads. PMID:32849857
SlGID1a Is a Putative Candidate Gene for qtph1.1, a Major-Effect Quantitative Trait Locus Controlling Tomato Plant Height. PMID:32849843
Stable SNP Allele Associations With High Grain Zinc Content in Polished Rice (Oryza sativa L.) Identified Based on ddRAD Sequencing. PMID:32849786
Short and Long-Read Sequencing Survey of the Dynamic Transcriptomes of African Swine Fever Virus and the Host Cells. PMID:32849785
Genetic Diversity and Selection Signatures Within Diannan Small-Ear Pigs Revealed by Next-Generation Sequencing. PMID:32849777
A Temporal Diversity Analysis of Brazilian Begomoviruses in Tomato Reveals a Decrease in Species Richness between 2003 and 2016. PMID:32849745
Population Genomics Reveals Demographic History and Genomic Differentiation of Populus davidiana and Populus tremula. PMID:32849683
New Plasmodium vivax Genomes From the China-Myanmar Border. PMID:32849480
Comparative Analysis of Clinical and Environmental Strains of Exophiala spinifera by Long-Reads Sequencing and RNAseq Reveal Adaptive Strategies. PMID:32849462
Exposure of the Opportunistic Marine Pathogen Photobacterium damselae subsp. damselae to Human Body Temperature Is a Stressful Condition That Shapes the Transcriptome, Viability, Cell Morphology, and Virulence. PMID:32849395
Genomic Surveillance of Ceftriaxone-Resistant Escherichia coli in Western New York Suggests the Extended-Spectrum β-Lactamase bla CTX-M-27 Is Emerging on Distinct Plasmids in ST38. PMID:32849376
Defining the Helicobacter pylori Disease-Specific Antigenic Repertoire. PMID:32849324
Defining Culture Conditions for the Hidden Nitrite-Oxidizing Bacterium Nitrolancea. PMID:32849321
POPOVICH, encoding a C2H2 zinc-finger transcription factor, plays a central role in the development of a key innovation, floral nectar spurs, in Aquilegia. PMID:32848061
Repair of an Attenuated Low-Passage Murine Cytomegalovirus Bacterial Artificial Chromosome Identifies a Novel Spliced Gene Essential for Salivary Gland Tropism. PMID:32847854
Improved reference genome of the arboviral vector Aedes albopictus. PMID:32847630
Genome-wide capture sequencing to detect hepatitis C virus at the end of antiviral therapy. PMID:32847527
Metastatic Burden Defines Clinically and Biologically Distinct Subgroups of Stage 4 High-Risk Neuroblastoma. PMID:32847064
Viral Metagenomic Analysis of Aedes albopictus Mosquitos from Southern Switzerland. PMID:32846980
Thermus thermophilus Argonaute Functions in the Completion of DNA Replication. PMID:32846159
Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning. PMID:32846133
Demographic history shaped geographical patterns of deleterious mutation load in a broadly distributed Pacific Salmon. PMID:32845885
First record of a tandem-repeat region within the mitochondrial genome of Clonorchis sinensis using a long-read sequencing approach. PMID:32845881
The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription. PMID:32845241
Clusters of polymorphic transmembrane genes control resistance to schistosomes in snail vectors. PMID:32845238
The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen. PMID:32843722
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations. PMID:32843717
910 metagenome-assembled genomes from the phytobiomes of three urban-farmed leafy Asian greens. PMID:32843634
A Chromosome-Scale Genome Assembly for the Fusarium oxysporum Strain Fo5176 To Establish a Model Arabidopsis-Fungal Pathosystem. PMID:32843521
MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity. PMID:32842611
Horizontal transmission and recombination maintain forever young bacterial symbiont genomes. PMID:32841233
Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys. PMID:32841214
Bifidobacterium adolescentis as a key member of the human gut microbiota in the production of GABA. PMID:32839473
Whole-genome sequencing and gene network modules predict gemcitabine/carboplatin-induced myelosuppression in non-small cell lung cancer patients. PMID:32839457
The Emergence of H7N7 Highly Pathogenic Avian Influenza Virus from Low Pathogenicity Avian Influenza Virus Using an in ovo Embryo Culture Model. PMID:32839404
Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors. PMID:32839274
HPC-REDItools: a novel HPC-aware tool for improved large scale RNA-editing analysis. PMID:32838738
Comparing a new method for mapping nucleosomes in simian virus 40 chromatin to standard procedures. PMID:32838633
The Dynamics, Causes, and Impacts of Mammalian Evolutionary Rates Revealed by the Analyses of Capybara Draft Genome Sequences. PMID:32835375
Draft Genomes of Amaranthus tuberculatus, Amaranthus hybridus, and Amaranthus palmeri. PMID:32835372
High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms. PMID:32833988
ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression. PMID:32832616
ChIA-PIPE: A fully automated pipeline for comprehensive ChIA-PET data analysis and visualization. PMID:32832596
Population structure and genetic diversity of watermelon (Citrullus lanatus) based on SNP of chloroplast genome. PMID:32832334
There is no magic bullet: the importance of testing reference gene stability in RT-qPCR experiments across multiple closely related species. PMID:32832268
Long-read individual-molecule sequencing reveals CRISPR-induced genetic heterogeneity in human ESCs. PMID:32831134
Using short read sequencing to characterise balanced reciprocal translocations in pigs. PMID:32831014
Towards standardization guidelines for in silico approaches in personalized medicine. PMID:32827396
Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals. PMID:32825847
Comparison of Poly-A+ Selection and rRNA Depletion in Detection of lncRNA in Two Equine Tissues Using RNA-seq. PMID:32825772
Metabolic Responses of Carotenoid and Cordycepin Biosynthetic Pathways in Cordyceps militaris under Light-Programming Exposure through Genome-Wide Transcriptional Analysis. PMID:32825642
Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells. PMID:32825120
Host-Pathogen Interactions between Xanthomonas fragariae and Its Host Fragaria × ananassa Investigated with a Dual RNA-Seq Analysis. PMID:32824783
Development of High-Density Genetic Linkage Maps and Identification of Loci for Chestnut Gall Wasp Resistance in Castanea spp. PMID:32824716
Do Metabolomics and Taxonomic Barcode Markers Tell the Same Story about the Evolution of Saccharomyces sensu stricto Complex in Fermentative Environments? PMID:32824262
A-to-I RNA editing in bacteria increases pathogenicity and tolerance to oxidative stress. PMID:32822429
Spectrum of clinical features and genetic variants in mevalonate kinase (MVK) gene of South Indian families suffering from Hyperimmunoglobulin D Syndrome. PMID:32822427
Genome-Wide Mapping of DNA Methylation 5mC by Methylated DNA Immunoprecipitation (MeDIP)-Sequencing. PMID:32822040
Robust partitioning of microRNA targets from downstream regulatory changes. PMID:32821933
Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo. PMID:32821827
The diet of otters (Lutra lutra) on the Agri river system, one of the most important presence sites in Italy: a molecular approach. PMID:32821542
Genome-wide Cas9 binding specificity in Saccharomyces cerevisiae. PMID:32821531
Genome sequencing and population genomics modeling provide insights into the local adaptation of weeping forsythia. PMID:32821413
Streptomyces harenosi sp. nov., a home for a gifted strain isolated from Indonesian sand dune soil. PMID:32821037
Elucidation of resistance signaling and identification of powdery mildew resistant mapping loci (ClaPMR2) during watermelon-Podosphaera xanthii interaction using RNA-Seq and whole-genome resequencing approach. PMID:32820191
Distinct kinesin motors drive two types of maize neocentromeres. PMID:32820038
Phf21b imprints the spatiotemporal epigenetic switch essential for neural stem cell differentiation. PMID:32820037
CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression. PMID:32820034
DNA polymerase stalling at structured DNA constrains the expansion of short tandem repeats. PMID:32819438
Ovine congenital progressive muscular dystrophy (OCPMD) is a model of TNNT1 congenital myopathy. PMID:32819427
Using spatial genetics to quantify mosquito dispersal for control programs. PMID:32819378
Comparative genomic analysis of Flavobacteriaceae: insights into carbohydrate metabolism, gliding motility and secondary metabolite biosynthesis. PMID:32819293
SARS-CoV-2 exhibits intra-host genomic plasticity and low-frequency polymorphic quasispecies. PMID:32818852
Using whole-genome sequencing data to derive the homologous recombination deficiency scores. PMID:32818150
Transcriptome profiling of raspberry (Rubus idaeus Var. Amira) in response to infection by tomato ringspot virus (ToRSV). PMID:32817888
Transcriptomic dataset of wild type and phoP mutant Pectobacterium versatile. PMID:32817874
Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines. PMID:32817744
Molecular causes of an evolutionary shift along the parasitism-mutualism continuum in a bacterial symbiont. PMID:32817434
Maize ANT1 modulates vascular development, chloroplast development, photosynthesis, and plant growth. PMID:32817425
Molecular Characterization of Influenza C Viruses from Outbreaks in Hong Kong SAR, China. PMID:32817211
Draft Genome Sequence of Thermanaeromonas sp. Strain C210, Isolated in the Presence of Carbon Monoxide. PMID:32817147
Alternative Splicing During the Chlamydomonas reinhardtii Cell Cycle. PMID:32817123
RNA-Bloom enables reference-free and reference-guided sequence assembly for single-cell transcriptomes. PMID:32817073
Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite. PMID:32816370
A hybrid pipeline for reconstruction and analysis of viral genomes at multi-organ level. PMID:32815536
Optimizing bacteriophage engineering through an accelerated evolution platform. PMID:32814789
Dead cells release a 'necrosignal' that activates antibiotic survival pathways in bacterial swarms. PMID:32814767
Divergence, gene flow, and the origin of leapfrog geographic distributions: The history of colour pattern variation in Phyllobates poison-dart frogs. PMID:32814358
Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data across 27 Tissue Types. PMID:32814038
Species-Specific Evolution of Ebola Virus during Replication in Human and Bat Cells. PMID:32814037
Marked mitochondrial genetic variation in individuals and populations of the carcinogenic liver fluke Clonorchis sinensis. PMID:32813714
FASTQINS and ANUBIS: two bioinformatic tools to explore facts and artifacts in transposon sequencing and essentiality studies. PMID:32813015
Precision design of stable genetic circuits carried in highly-insulated E. coli genomic landing pads. PMID:32812710
Fine mapping of a leaf flattening gene Bralcm through BSR-Seq in Chinese cabbage (Brassica rapa L. ssp. pekinensis). PMID:32811880
The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes. PMID:32811853
A specific combination of dual index adaptors decreases the sensitivity of amplicon sequencing with the Illumina platform. PMID:32810209
Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems. PMID:32810208
Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation. PMID:32810179
3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors. PMID:32810173
A haplotype-resolved, de novo genome assembly for the wood tiger moth (Arctia plantaginis) through trio binning. PMID:32808665
Permissive epigenomes endow reprogramming competence to transcriptional regulators. PMID:32807969
Plasmid-based complementation of large deletions in Phaeodactylum tricornutum biosynthetic genes generated by Cas9 editing. PMID:32807825
Characterization of integrated prophages within diverse species of clinical nontuberculous mycobacteria. PMID:32807206
Dynamic nanopore long-read sequencing analysis of HIV-1 splicing events during the early steps of infection. PMID:32807178
Insights into Mobile Genetic Elements of the Biocide-Degrading Bacterium Pseudomonas nitroreducens HBP-1. PMID:32806781
Gene expression profiles during postnatal development of the liver and pancreas in giant pandas. PMID:32805731
CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea. PMID:32804988
Systematic identification of functional SNPs interrupting 3'UTR polyadenylation signals. PMID:32804959
A comparison of humans and baboons suggests germline mutation rates do not track cell divisions. PMID:32804933
Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation. PMID:32804079
Differential DNA methylation analysis across the promoter regions using methylated DNA immunoprecipitation sequencing profiling of porcine loin muscle. PMID:32801562
Implications of Foraging and Interspecies Interactions of Birds for Carriage of Escherichia coli Strains Resistant to Critically Important Antimicrobials. PMID:32801178
HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads. PMID:32801147
Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing. PMID:32799528
Circadian regulation of chemotherapy-induced peripheral neuropathic pain and the underlying transcriptomic landscape. PMID:32796949
DNA methylation is reconfigured at the onset of reproduction in rice shoot apical meristem. PMID:32796936
Tomato Brown Rugose Fruit Virus Contributes to Enhanced Pepino Mosaic Virus Titers in Tomato Plants. PMID:32796777
Alterations of Rice (Oryza sativa L.) DNA Methylation Patterns Associated with Gene Expression in Response to Rice Black Streaked Dwarf Virus. PMID:32796598
Development of an NGS-Based Workflow for Improved Monitoring of Circulating Plasmids in Support of Risk Assessment of Antimicrobial Resistance Gene Dissemination. PMID:32796589
FATTY ACID DESATURASE5 Is Required to Induce Autoimmune Responses in Gigantic Chloroplast Mutants of Arabidopsis. PMID:32796124
Chromosome-Scale Assembly of the Bread Wheat Genome Reveals Thousands of Additional Gene Copies. PMID:32796007
Identification of the First Oomycete Mating-type Locus Sequence in the Grapevine Downy Mildew Pathogen, Plasmopara viticola. PMID:32795448
ACValidator: A novel assembly-based approach for in silico verification of circular RNAs. PMID:32793805
DNA Methyltransferase 1 (DNMT1) Function Is Implicated in the Age-Related Loss of Cortical Interneurons. PMID:32793592
Cysteine and Methionine Biosynthetic Enzymes Have Distinct Effects on Seed Nutritional Quality and on Molecular Phenotypes Associated With Accumulation of a Methionine-Rich Seed Storage Protein in Rice. PMID:32793268
QTL Mapping and Marker Development for Tolerance to Sulfur Phytotoxicity in Melon (Cucumis melo). PMID:32793259
Genomic Characteristics and Potential Metabolic Adaptations of Hadal Trench Roseobacter and Alteromonas Bacteria Based on Single-Cell Genomics Analyses. PMID:32793171
Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population. PMID:32792643
Comparative genomics of muskmelon reveals a potential role for retrotransposons in the modification of gene expression. PMID:32792560
De Novo Assembly of the Northern Cardinal (Cardinalis cardinalis) Genome Reveals Candidate Regulatory Regions for Sexually Dichromatic Red Plumage Coloration. PMID:32792344
SIGAR: Inferring Features of Genome Architecture and DNA Rearrangements by Split-Read Mapping. PMID:32790832
Exon sequencing mutation detection algorithm based on PCR matching. PMID:32790736
Mutations in m6A consensus motifs are suppressed in the m6A modified genes in human cancer cells. PMID:32790688
Unravelling the changes during induced vitellogenesis in female European eel through RNA-Seq: What happens to the liver? PMID:32790680
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. PMID:32790644
A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping. PMID:32789024
Italian weedy rice-A case of de-domestication? PMID:32788993
Lousy grouse: Comparing evolutionary patterns in Alaska galliform lice to understand host evolution and host-parasite interactions. PMID:32788987
Whole-genome resequencing reveals the pleistocene temporal dynamics of Branchiostoma belcheri and Branchiostoma floridae populations. PMID:32788973
Developmental changes in the accessible chromatin, transcriptome and Ascl1-binding correlate with the loss in Müller Glial regenerative potential. PMID:32788677
Patterns of DNA variation between the autosomes, the X chromosome and the Y chromosome in Bos taurus genome. PMID:32788585
Phenotypic and molecular marker analysis uncovers the genetic diversity of the grass Stenotaphrum secundatum. PMID:32787786
Population analysis of the Korean native duck using whole-genome sequencing data. PMID:32787779
Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells. PMID:32786181
Downy Mildew effector HaRxL21 interacts with the transcriptional repressor TOPLESS to promote pathogen susceptibility. PMID:32785253
Genetic Diversity and Genetic Structure of the Wild Tsushima Leopard Cat from Genome-Wide Analysis. PMID:32784782
Modeling the Diversity of Epithelial Ovarian Cancer through Ten Novel Well Characterized Cell Lines Covering Multiple Subtypes of the Disease. PMID:32784519
Genomic Analysis of Localized High-Risk Prostate Cancer Circulating Tumor Cells at the Single-Cell Level. PMID:32784507
Strain-Level Metagenomic Data Analysis of Enriched In Vitro and In Silico Spiked Food Samples: Paving the Way towards a Culture-Free Foodborne Outbreak Investigation Using STEC as a Case Study. PMID:32784459
Complex Variant Discovery Using Discordant Cluster Normalization. PMID:32783649
Gene expression analysis of primary gingival cancer by whole exome sequencing in thirteen Chinese patients. PMID:32782722
Next generation sequencing-based analysis of mitochondrial DNA characteristics in plasma extracellular vesicles of patients with hepatocellular carcinoma. PMID:32782600
Overexpression of miR-669m inhibits erythroblast differentiation. PMID:32782283
A new plasmid carrying mphA causes prevalence of azithromycin resistance in enterotoxigenic Escherichia coli serogroup O6. PMID:32782021
Upregulation of the MYB2 Transcription Factor Is Associated with Increased Accumulation of Anthocyanin in the Leaves of Dendrobium bigibbum. PMID:32781758
Repression of the B cell identity factor Pax5 is not required for plasma cell development. PMID:32780801
Identification of transcription factors controlling floral morphology in wild Petunia species with contrasting pollination syndromes. PMID:32780443
Functional characterization of a PROTAC directed against BRAF mutant V600E. PMID:32778845
N6-Methyladenosine co-transcriptionally directs the demethylation of histone H3K9me2. PMID:32778823
Transcriptome sequencing supports a conservation of macrophage polarization in fish. PMID:32778701
Mucosal delivery of ESX-1-expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes. PMID:32778586
Enhancer evolutionary co-option through shared chromatin accessibility input. PMID:32778581
LongAGE: defining breakpoints of genomic structural variants through optimal and memory efficient alignments of long reads. PMID:32777815
JNK pathway restricts DENV2, ZIKV and CHIKV infection by activating complement and apoptosis in mosquito salivary glands. PMID:32776975
A novel composition of two heterozygous GFM1 mutations in a Chinese child with epilepsy and mental retardation. PMID:32776492
Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning. PMID:32774784
Introgression Leads to Genomic Divergence and Responsible for Important Traits in Upland Cotton. PMID:32774337
Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants. PMID:32773032
Clinical impact of a cancer genomic profiling test using an in-house comprehensive targeted sequencing system. PMID:32772458
Exome sequencing links CEP120 mutation to maternally derived aneuploid conception risk. PMID:32772081
The Potential Role of Preoperative Pain, Catastrophizing, and Differential Gene Expression on Pain Outcomes after Pediatric Spinal Fusion. PMID:32771349
SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells. PMID:32770939
Genomic Evidence for Sensorial Adaptations to a Nocturnal Predatory Lifestyle in Owls. PMID:32770228
The first evidence for Late Pleistocene dogs in Italy. PMID:32770100
Genomic and enzymatic evidence of acetogenesis by anaerobic methanotrophic archaea. PMID:32770005
Whole genome analysis reveals aneuploidies in early pregnancy loss in the horse. PMID:32769994
Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites. PMID:32769985
Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates. PMID:32769975
Merging Metagenomics and Spatial Epidemiology To Understand the Distribution of Antimicrobial Resistance Genes from Enterobacteriaceae in Wild Owls. PMID:32769191
A Rosaceae Family-Level Approach To Identify Loci Influencing Soluble Solids Content in Blackberry for DNA-Informed Breeding. PMID:32769135
Integrative analyses of single-cell transcriptome and regulome using MAESTRO. PMID:32767996
Predictive features of gene expression variation reveal mechanistic link with differential expression. PMID:32767663
Ribbon: intuitive visualization for complex genomic variation. PMID:32766814
Pseudohyphal differentiation in Komagataella phaffii: investigating the FLO gene family. PMID:32766781
Cell-Free DNA in Blood Reveals Significant Cell, Tissue and Organ Specific injury and Predicts COVID-19 Severity. PMID:32766608
Korean Genome Project: 1094 Korean personal genomes with clinical information. PMID:32766443
A Genomewide Scan for Genetic Structure and Demographic History of Two Closely Related Species, Rhododendron dauricum and R. mucronulatum (Rhododendron, Ericaceae). PMID:32765570
Phylogenomic Relationships and Evolution of Polyploid Salix Species Revealed by RAD Sequencing Data. PMID:32765560
Combined Transcriptome Sequencing of Mycoplasma hyopneumoniae and Infected Pig Lung Tissue Reveals Up-Regulation of Bacterial F1-Like ATPase and Down-Regulation of the P102 Cilium Adhesin in vivo. PMID:32765473
Comparative assessment of genetic diversity matrices and clustering methods in white Guinea yam (Dioscorea rotundata) based on morphological and molecular markers. PMID:32764649
Comprehensive Analyses of SARS-CoV-2 Transmission in a Public Health Virology Laboratory. PMID:32764372
Identification of a Metagenome-Assembled Genome of an Uncultured Methyloceanibacter sp. Strain Acquired from an Activated Sludge System Used for Landfill Leachate Treatment. PMID:32763946
Genome Sequences of Six SARS-CoV-2 Strains Isolated in Morocco, Obtained Using Oxford Nanopore MinION Technology. PMID:32763945
Whole-Genome Sequence of an Orf Virus Isolate Derived from a Cell Culture Infected with Contagious Ecthyma Vaccine. PMID:32763944
Terabase Metagenome Sequencing of Grassland Soil Microbiomes. PMID:32763940
Draft Genome Sequence of a Multicountry Outbreak-Related Listeria monocytogenes Sequence Type 1247 Strain, VLTRLM2013. PMID:32763938
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. PMID:32762776
Rapid evolutionary changes in gene expression in response to climate fluctuations. PMID:32761923
Well-balanced immune response and protective efficacy induced by a single dose of live attenuated tetravalent dengue vaccine (KD-382) in monkeys. PMID:32760828
ddRAD-seq derived genome-wide SNPs, high density linkage map and QTLs for fruit quality traits in strawberry (Fragaria x ananassa). PMID:32760641
Evaluating the effect of reference genome divergence on the analysis of empirical RADseq datasets. PMID:32760550
Evidence of capacitation in the parasitoid wasp, Nasonia vitripennis, and its potential role in sex allocation. PMID:32760522
The Isolation and Genome Sequencing of Five Novel Bacteriophages From the Rumen Active Against Butyrivibrio fibrisolvens. PMID:32760371
Determination of novel CYP2D6 haplotype using the targeted sequencing followed by the long-read sequencing and the functional characterization in the Japanese population. PMID:32759992
Ribo-Pop: simple, cost-effective, and widely applicable ribosomal RNA depletion. PMID:32759389
Diploid genome architecture revealed by multi-omic data of hybrid mice. PMID:32759226
HDA6-dependent histone deacetylation regulates mRNA polyadenylation in Arabidopsis. PMID:32759225
A comprehensive DNA panel next generation sequencing approach supporting diagnostics and therapy prediction in neurooncology. PMID:32758285
Analyses of key genes involved in Arctic adaptation in polar bears suggest selection on both standing variation and de novo mutations played an important role. PMID:32758141
Seqminer2: an efficient tool to query and retrieve genotypes for statistical genetics analyses from biobank scale sequence dataset. PMID:32756942
Targeted bisulfite sequencing for biomarker discovery. PMID:32755621
The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress. PMID:32755596
Comparison Between Core Set Selection Methods Using Different Illumina Marker Platforms: A Case Study of Assessment of Diversity in Wheat. PMID:32754184
Contribution of Viral Genomic Diversity to Oyster Susceptibility in the Pacific Oyster Mortality Syndrome. PMID:32754139
Species Boundaries and Molecular Markers for the Classification of 16SrI Phytoplasmas Inferred by Genome Analysis. PMID:32754131
Sequential Whole Exome Sequencing Reveals Somatic Mutations Associated with Platinum Response in NSCLC. PMID:32753889
Contribution to the ecology of the Italian hare (Lepus corsicanus). PMID:32753640
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas. PMID:32753598
Escherichia coli Has a Unique Transcriptional Program in Long-Term Stationary Phase Allowing Identification of Genes Important for Survival. PMID:32753505
Bactopia: a Flexible Pipeline for Complete Analysis of Bacterial Genomes. PMID:32753501
The whale shark genome reveals how genomic and physiological properties scale with body size. PMID:32753383
Investigation of Macrolide Resistance Genotypes in Mycoplasma bovis Isolates from Canadian Feedlot Cattle. PMID:32751555
Population Genetic Analysis of Ten Geographically Isolated Tibetan Pig Populations. PMID:32751240
Fine-needle aspiration as an alternative to core needle biopsy for tumour molecular profiling in precision oncology: prospective comparative study of next-generation sequencing in cancer patients included in the SHIVA02 trial. PMID:32750212
Development and validation of a universal blood donor genotyping platform: a multinational prospective study. PMID:32750130
Whole-genome de novo assemblies reveal extensive structural variations and dynamic organelle-to-nucleus DNA transfers in African and Asian rice. PMID:32748498
Alignment and quantification of ChIP-exo crosslinking patterns reveal the spatial organization of protein-DNA complexes. PMID:32747934
Single-cell atlas of colonic CD8+ T cells in ulcerative colitis. PMID:32747828
Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade-specific epigenome and transcriptome landscapes. PMID:32747824
Whole-exome sequencing and genome-wide evolutionary analyses identify novel candidate genes associated with infrared perception in pit vipers. PMID:32747674
Ancient genomes in South Patagonia reveal population movements associated with technological shifts and geography. PMID:32747648
Temporal encoding of bacterial identity and traits in growth dynamics. PMID:32747578
Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution. PMID:32747416
Novel imaging and clinical phenotypes of CONDSIAS disorder caused by a homozygous frameshift variant of ADPRHL2: a case report. PMID:32746785
Identification of SNPs and InDels associated with berry size in table grapes integrating genetic and transcriptomic approaches. PMID:32746778
High relatedness of invasive multi-drug resistant non-typhoidal Salmonella genotypes among patients and asymptomatic carriers in endemic informal settlements in Kenya. PMID:32745137
Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period. PMID:32745129
Genomic and transcriptomic evidence for descent from Plasmodium and loss of blood schizogony in Hepatocystis parasites from naturally infected red colobus monkeys. PMID:32745123
Population genomics identifies a distinct Plasmodium vivax population on the China-Myanmar border of Southeast Asia. PMID:32745103
Machine learning-based classification and diagnosis of clinical cardiomyopathies. PMID:32744882
A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation. PMID:32744504
NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency. PMID:32744500
Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression. PMID:32743548
Control of translation during the unfolded protein response in maize seedlings: Life without PERKs. PMID:32743235
A cost-effective barcode system for maize genetic discrimination based on bi-allelic InDel markers. PMID:32742299
Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors. PMID:32738923
Long-read sequencing reveals widespread intragenic structural variants in a recent allopolyploid crop plant. PMID:32737959
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration. PMID:32737416
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis. PMID:32737409
Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. PMID:32737294
Mapping the Efficacy and Mode of Action of Ethylzingerone [4-(3-Ethoxy-4-Hydroxyphenyl) Butan-2-One] as an Active Agent against Burkholderia Bacteria. PMID:32737133
The thick aleurone1 Gene Encodes a NOT1 Subunit of the CCR4-NOT Complex and Regulates Cell Patterning in Endosperm. PMID:32737073
Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors. PMID:32735851
Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2. PMID:32735849
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. PMID:32735845
Highly Efficient Knockout of a Squid Pigmentation Gene. PMID:32735817
Regional sequence expansion or collapse in heterozygous genome assemblies. PMID:32735589
Development and validation of Houston Methodist Variant Viewer version 3: updates to our application for interpretation of next-generation sequencing data. PMID:32734171
Single Nucleotide Polymorphism Charting of P. patens Reveals Accumulation of Somatic Mutations During in vitro Culture on the Scale of Natural Variation by Selfing. PMID:32733496
Low Abundance of Methanotrophs in Sediments of Shallow Boreal Coastal Zones With High Water Methane Concentrations. PMID:32733420
Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method. PMID:32732980
Genomic epidemiology of Mycobacterium tuberculosis in Santa Catarina, Southern Brazil. PMID:32732910
Extensive Recombination Suppression and Epistatic Selection Causes Chromosome-Wide Differentiation of a Selfish Sex Chromosome in Drosophila pseudoobscura. PMID:32732371
MYC2-Activated TRICHOME BIREFRINGENCE-LIKE37 Acetylates Cell Walls and Enhances Herbivore Resistance. PMID:32732351
Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of Dictyostelium discoideum. PMID:32732307
Cross-species analysis of enhancer logic using deep learning. PMID:32732264
Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model. PMID:32731855
Identifying the key regulators that promote cell-cycle activity in the hearts of early neonatal pigs after myocardial injury. PMID:32730272
5-Formylcytosine landscapes of human preimplantation embryos at single-cell resolution. PMID:32730243
Incomplete removal of ribosomal RNA can affect chromatin RNA-seq data analysis. PMID:32729748
Generation of a Hutchinson-Gilford progeria syndrome monkey model by base editing. PMID:32729022
Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors. PMID:32728700
Occupancy maps of 208 chromatin-associated proteins in one human cell type. PMID:32728244
Spatiotemporal DNA methylome dynamics of the developing mouse fetus. PMID:32728242
Mechanisms of stretch-mediated skin expansion at single-cell resolution. PMID:32728211
Gradual polyploid genome evolution revealed by pan-genomic analysis of Brachypodium hybridum and its diploid progenitors. PMID:32728126
Detecting sample swaps in diverse NGS data types using linkage disequilibrium. PMID:32728101
Transcriptional activity and strain-specific history of mouse pseudogenes. PMID:32728065
Phylogenomic Analyses of Non-Dikarya Fungi Supports Horizontal Gene Transfer Driving Diversification of Secondary Metabolism in the Amphibian Gastrointestinal Symbiont, Basidiobolus. PMID:32727924
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas. PMID:32727536
Completion of draft bacterial genomes by long-read sequencing of synthetic genomic pools. PMID:32727443
Distinct Molecular Landscape of Epstein-Barr Virus Associated Pulmonary Lymphoepithelioma-Like Carcinoma Revealed by Genomic Sequencing. PMID:32726920
FANCY: fast estimation of privacy risk in functional genomics data. PMID:32726397
Transcriptome analysis of contrasting resistance to herbivory by Empoasca fabae in two shrub willow species and their hybrid progeny. PMID:32726362
Interplay of RFX transcription factors 1, 2 and 3 in motile ciliogenesis. PMID:32725242
X-Linked Signature of Reproductive Isolation in Humans is Mirrored in a Howler Monkey Hybrid Zone. PMID:32725191
Genome-Wide Identification and Analysis of Variants in Domestic and Wild Bactrian Camels Using Whole-Genome Sequencing Data. PMID:32724789
A robust method for the rapid detection of microsatellite instability in colorectal cancer. PMID:32724444
Increased frequency of ESR1 mutation in metastatic breast cancer by dosing selective estrogen receptor modulator followed by aromatase inhibitor. PMID:32724363
Spatial and morphological reorganization of endosymbiosis during metamorphosis accommodates adult metabolic requirements in a weevil. PMID:32723830
A 1.7-Mb chromosomal inversion downstream of a PpOFP1 gene is responsible for flat fruit shape in peach. PMID:32722872
Mitochondrial DNA Damage and Brain Aging in Human Immunodeficiency Virus. PMID:32722761
Genomic Landscape of Mutational Biases in the Pacific Oyster Crassostrea gigas. PMID:32722758
A Transposon Story: From TE Content to TE Dynamic Invasion of Drosophila Genomes Using the Single-Molecule Sequencing Technology from Oxford Nanopore. PMID:32722451
Parental Selenium Nutrition Affects the One-Carbon Metabolism and the Hepatic DNA Methylation Pattern of Rainbow Trout (Oncorhynchus mykiss) in the Progeny. PMID:32722369
Identification of Long-Distance Transmissible mRNA between Scion and Rootstock in Cucurbit Seedling Heterografts. PMID:32722102
Sequencing and Analysis of the Sex Determination Region of Populus trichocarpa. PMID:32722098
Isolation and phylogenetic analysis of SARS-CoV-2 variants collected in Russia during the COVID-19 outbreak. PMID:32721529
Multiple novel non-canonically transcribed sub-genomic mRNAs produced by avian coronavirus infectious bronchitis virus. PMID:32720890
Scalability and cost-effectiveness analysis of whole genome-wide association studies on Google Cloud Platform and Amazon Web Services. PMID:32719837
First Genome Sequences of Two Multidrug-Resistant Candida haemulonii var. vulnera Isolates From Pediatric Patients With Candidemia. PMID:32719671
The transcription factor BCL-6 controls early development of innate-like T cells. PMID:32719520
A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples. PMID:32719001
Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues. PMID:32718348
Bovine breed-specific augmented reference graphs facilitate accurate sequence read mapping and unbiased variant discovery. PMID:32718320
The evolution and functional divergence of the histone H2B family in plants. PMID:32716939
Multiplex melanoma families are enriched for polygenic risk. PMID:32716505
Comparative genomics of rice false smut fungi Ustilaginoidea virens Uv-Gvt strain from India reveals genetic diversity and phylogenetic divergence. PMID:32714737
Chromosome Level Genome Assembly of Andrographis paniculata. PMID:32714378
Analysis of quantitative trait loci for fertility restoration in seven F2 populations derived from sorghum F1 hybrids bred in Japan. PMID:32714061
Single-base deletion in GmCHR5 increases the genistein-to-daidzein ratio in soybean seed. PMID:32714048
Differences in local population history at the finest level: the case of the Estonian population. PMID:32712624
Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype. PMID:32712105
Correlation of drug resistance with single nucleotide variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of M. tuberculosis. PMID:32711461
The wheat pathogen Zymoseptoria tritici senses and responds to different wavelengths of light. PMID:32711450
Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1high memory phenotype CD4 T cells. PMID:32709717
Improved Reference Genome for Cyclotella cryptica CCMP332, a Model for Cell Wall Morphogenesis, Salinity Adaptation, and Lipid Production in Diatoms (Bacillariophyta). PMID:32709619
Integrated Analysis of Tissue-Specific Promoter Methylation and Gene Expression Profile in Complex Diseases. PMID:32709145
In vitro Edwardsiella piscicida CK108 Transcriptome Profiles with Subinhibitory Concentrations of Phenol and Formalin Reveal New Insights into Bacterial Pathogenesis Mechanisms. PMID:32709101
Profiling of Mitochondrial DNA Heteroplasmy in a Prospective Oral Squamous Cell Carcinoma Study. PMID:32708892
Target-Genes Reveal Species and Genotypic Specificity of Anthocyanin Pigmentation in Citrus and Related Genera. PMID:32708660
High-Quality Resolution of the Outbreak-Related Zika Virus Genome and Discovery of New Viruses Using Ion Torrent-Based Metatranscriptomics. PMID:32708079
High-Throughput Sequencing of Gastric Cancer Patients: Unravelling Genetic Predispositions Towards an Early-Onset Subtype. PMID:32708070
Insights from Population Genomics to Enhance and Sustain Biological Control of Insect Pests. PMID:32708047
Cell-Type Specificity of Genomic Imprinting in Cerebral Cortex. PMID:32707083
Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. PMID:32707082
Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma. PMID:32707078
Beneficial effects of IL-4 and IL-6 on rat neonatal target cardiac cells. PMID:32704142
Application of next generation sequencing (NGS) for descriptive analysis of 30 genomes of Leishmania infantum isolates in Middle-North Brazil. PMID:32704096
Trajectory analysis quantifies transcriptional plasticity during macrophage polarization. PMID:32703960
Evolution and epidemic spread of SARS-CoV-2 in Brazil. PMID:32703910
Draft Genome Sequences of Three Fusarium circinatum Isolates Used To Inoculate a Pedigreed Population of Pinus elliottii Seedlings. PMID:32703836
Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas. PMID:32703790
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies. PMID:32703768
Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer. PMID:32703318
SimuSCoP: reliably simulate Illumina sequencing data based on position and context dependent profiles. PMID:32703148
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100-Reactive CD4+ T-Regulatory Cells. PMID:32703007
Mating system is correlated with immunogenetic diversity in sympatric species of Peromyscine mice. PMID:32701975
ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming. PMID:32701507
Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos. PMID:32701060
Transposase-assisted tagmentation of RNA/DNA hybrid duplexes. PMID:32701057
Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution. PMID:32699356
A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response. PMID:32699191
M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer. PMID:32699181
A Race against Time: Reduced Azithromycin Susceptibility in Salmonella enterica Serovar Typhi in Pakistan. PMID:32699118
Epigenetic Suppression of Transgenic T-cell Receptor Expression via Gamma-Retroviral Vector Methylation in Adoptive Cell Transfer Therapy. PMID:32699033
Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility. PMID:32699019
Population Genomic Analyses of the Sea Urchin Echinometra sp. EZ across an Extreme Environmental Gradient. PMID:32697837
ASNEO: Identification of personalized alternative splicing based neoantigens with RNA-seq. PMID:32697765
Y-Chromosome Variation in Southern African Khoe-San Populations Based on Whole-Genome Sequences. PMID:32697300
A homozygote variant in the tRNA splicing endonuclease subunit 54 causes pontocerebellar hypoplasia in a consanguineous Iranian family. PMID:32697043
Identification and Analysis of p53-Regulated Enhancers in Hepatic Carcinoma. PMID:32695760
The Clinical and Molecular Characterization of Gastric Cancer Patients in Qinghai-Tibetan Plateau. PMID:32695679
Mobilization of Antibiotic Resistance: Are Current Approaches for Colocalizing Resistomes and Mobilomes Useful? PMID:32695079
Wild-Type MIC Distribution for Re-evaluating the Critical Concentration of Anti-TB Drugs and Pharmacodynamics Among Tuberculosis Patients From South India. PMID:32695072
Identification of Hypoxia-Specific Biomarkers in Salmonids Using RNA-Sequencing and Validation Using High-Throughput qPCR. PMID:32694198
Reference genome and transcriptome informed by the sex chromosome complement of the sample increase ability to detect sex differences in gene expression from RNA-Seq data. PMID:32693839
A unified catalog of 204,938 reference genomes from the human gut microbiome. PMID:32690973
Iron is not everything: unexpected complex metabolic responses between iron-cycling microorganisms. PMID:32690937
Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level. PMID:32690901
Genetic Diversity and Population Structure of Races of Fusarium oxysporum Causing Cotton Wilt. PMID:32690585
Comparative population genomic analysis uncovers novel genomic footprints and genes associated with small body size in Chinese pony. PMID:32689947
Genomics of sex allocation in the parasitoid wasp Nasonia vitripennis. PMID:32689940
Genomic diversity revealed by whole-genome sequencing in three Danish commercial pig breeds. PMID:32687196
Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs. PMID:32687060
S-phase-independent silencing establishment in Saccharomyces cerevisiae. PMID:32687055
Comprehensive investigation of RNF213 nonsynonymous variants associated with intracranial artery stenosis. PMID:32686731
Relative genomic impacts of translocation history, hatchery practices, and farm selection in Pacific oyster Crassostrea gigas throughout the Northern Hemisphere. PMID:32684965
Demographic history and genomics of local adaptation in blue tit populations. PMID:32684952
Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality. PMID:32681306
Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins. PMID:32681087
A comparison of proteomic, genomic, and osteological methods of archaeological sex estimation. PMID:32681049
Cross-species oncogenic signatures of breast cancer in canine mammary tumors. PMID:32680987
BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining. PMID:32680986
TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity. PMID:32680955
Long-Term Reciprocal Gene Flow in Wild and Domestic Geese Reveals Complex Domestication History. PMID:32680852
Integrating RNA-Seq with GWAS reveals novel insights into the molecular mechanism underpinning ketosis in cattle. PMID:32680461
Precise annotation of tick mitochondrial genomes reveals multiple copy number variation of short tandem repeats and one transposon-like element. PMID:32680454
The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer. PMID:32679899
Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer. PMID:32679108
QTL mapping and candidate gene analysis of cadmium accumulation in polished rice by genome-wide association study. PMID:32678216
Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach. PMID:32678143
Differential loss of effector genes in three recently expanded pandemic clonal lineages of the rice blast fungus. PMID:32677941
Genome-wide characterization of copy number variations in the host genome in genetic resistance to Marek's disease using next generation sequencing. PMID:32677890
Role of SARS-CoV-2 in altering the RNA binding protein and miRNA directed post-transcriptional regulatory networks in humans. PMID:32676599
Integrated analysis of optical mapping and whole-genome sequencing reveals intratumoral genetic heterogeneity in metastatic lung squamous cell carcinoma. PMID:32676329
Complete Genome Sequence of the Blochmannia Endosymbiont of Camponotus nipponensis. PMID:32675189
Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis. PMID:32674599
Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion. PMID:32673568
Nuclear role for human Argonaute-1 as an estrogen-dependent transcription coactivator. PMID:32673398
Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions. PMID:32673314
The origin of domestication genes in goats. PMID:32671210
RALF1-FERONIA complex affects splicing dynamics to modulate stress responses and growth in plants. PMID:32671204
A Novel PCNT Frame Shift Variant (c.7511delA) Causing Osteodysplastic Primordial Dwarfism of Majewski Type 2 (MOPD II). PMID:32671003
Natural Selection on Exonic SNPs Shapes Allelic Expression Imbalance (AEI) Adaptability in Lung Cancer Progression. PMID:32670357
BSA-Seq Discovery and Functional Analysis of Candidate Hessian Fly (Mayetiola destructor) Avirulence Genes. PMID:32670342
The Loss of the Inverted Repeat in the Putranjivoid Clade of Malpighiales. PMID:32670335
Evolutionary History of the Marchantia polymorpha Complex. PMID:32670318
MicroGMT: A Mutation Tracker for SARS-CoV-2 and Other Microbial Genome Sequences. PMID:32670259
Metabolomic Analysis of Aspergillus niger Isolated From the International Space Station Reveals Enhanced Production Levels of the Antioxidant Pyranonigrin A. PMID:32670208
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. PMID:32669714
New group of transmembrane proteins associated with desiccation tolerance in the anhydrobiotic midge Polypedilum vanderplanki. PMID:32669703
A first genetic linage map construction and QTL mapping for growth traits in Larimichthys polyactis. PMID:32669609
Phylogenetic Characterization Reveals Prevalent Shigella flexneri ST100 Clone in Beijing, China, 2005 to 2018. PMID:32669464
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. PMID:32668255
Impact of processing method on donated human breast milk microRNA content. PMID:32667939
Accuracy of short tandem repeats genotyping tools in whole exome sequencing data. PMID:32665844
Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration. PMID:32665240
Somalier: rapid relatedness estimation for cancer and germline studies using efficient genome sketches. PMID:32664994
Assessing Genome-Wide Diversity in European Hantaviruses through Sequence Capture from Natural Host Samples. PMID:32664593
The gut microbiome stability is altered by probiotic ingestion and improved by the continuous supplementation of galactooligosaccharide. PMID:32663059
Alternative Activation of Macrophages Is Accompanied by Chromatin Remodeling Associated with Lineage-Dependent DNA Shape Features Flanking PU.1 Motifs. PMID:32661179
Genetic polymorphism of Plasmodium falciparum circumsporozoite protein on Bioko Island, Equatorial Guinea and global comparative analysis. PMID:32660484
Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results. PMID:32660107
Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions. PMID:32659913
The Theory and Applications of Measuring Broad-Range and Chromosome-Wide Recombination Rate from Allele Frequency Decay around a Selected Locus. PMID:32658965
A non-canonical RNAi pathway controls virulence and genome stability in Mucorales. PMID:32658892
Insights into the evolution of symbiosis gene copy number and distribution from a chromosome-scale Lotus japonicus Gifu genome sequence. PMID:32658273
Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. PMID:32657756
Genetic profile of non-small cell lung cancer (NSCLC): A hospital-based survey in Jinhua. PMID:32657049
Novel Genetic Variations in Acute Myeloid Leukemia in Pakistani Population. PMID:32655615
Fine Mapping to Identify the Functional Genetic Locus for Red Coloration in Pyropia yezoensis Thallus. PMID:32655600
Sympatric speciation in mountain roses (Metrosideros) on an oceanic island. PMID:32654651
The role of copy-number variation in the reinforcement of sexual isolation between the two European subspecies of the house mouse. PMID:32654648
Genomic Analysis of the Only Blind Cichlid Reveals Extensive Inactivation in Eye and Pigment Formation Genes. PMID:32653909
Contributions of cis- and trans-Regulatory Evolution to Transcriptomic Divergence across Populations in the Drosophila mojavensis Larval Brain. PMID:32653899
Genomic analyses reveal the genetic basis of early maturity and identification of loci and candidate genes in upland cotton (Gossypium hirsutum L.). PMID:32652678
New insights into Arabidopsis transcriptome complexity revealed by direct sequencing of native RNAs. PMID:32652016
Biological rhythms in the deep-sea hydrothermal mussel Bathymodiolus azoricus. PMID:32651383
A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing. PMID:32651371
Normal Patterns of Histone H3K27 Methylation Require the Histone Variant H2A.Z in Neurospora crassa. PMID:32651262
Candidate genes for monitoring hydrogen peroxide resistance in the salmon louse, Lepeophtheirus salmonis. PMID:32650825
Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes. PMID:32650820
The extremely halotolerant black yeast Hortaea werneckii - a model for intraspecific hybridization in clonal fungi. PMID:32647617
A multigene phylogeny toward a new phylogenetic classification of Leotiomycetes. PMID:32647610
Evaluation of molecular subtypes and clonal selection during establishment of patient-derived tumor xenografts from gastric adenocarcinoma. PMID:32647357
The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain. PMID:32647123
Aberrantly expressed HORMAD1 disrupts nuclear localization of MCM8-MCM9 complex and compromises DNA mismatch repair in cancer cells. PMID:32647118
The earliest domestic cat on the Silk Road. PMID:32647113
Long-Read cDNA Sequencing Enables a "Gene-Like" Transcript Annotation of Transposable Elements. PMID:32647069
Characterization and Fine Mapping of a Yellow-Virescent Gene Regulating Chlorophyll Biosynthesis and Early Stage Chloroplast Development in Brassica napus. PMID:32646913
Genome-wide studies reveal the essential and opposite roles of ARID1A in controlling human cardiogenesis and neurogenesis from pluripotent stem cells. PMID:32646524
Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening. PMID:32645954
Evolution of Mutation Rate in Astronomically Large Phytoplankton Populations. PMID:32645145
The Lyme disease bacterium, Borrelia burgdorferi, stimulates an inflammatory response in human choroid plexus epithelial cells. PMID:32645014
Impact of insertion sequences on convergent evolution of Shigella species. PMID:32644999
Population genetics of wild Macaca fascicularis with low-coverage shotgun sequencing of museum specimens. PMID:32643146
Genome assembly of Chiococca alba uncovers key enzymes involved in the biosynthesis of unusual terpenoids. PMID:32642754
Near-chromosome level genome assembly of the fruit pest Drosophila suzukii using long-read sequencing. PMID:32641717
Staphylococcus Agr virulence is critical for epidermal colonization and associates with atopic dermatitis development. PMID:32641488
Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism. PMID:32641298
Degradation of key photosynthetic genes in the critically endangered semi-aquatic flowering plant Saniculiphyllum guangxiense (Saxifragaceae). PMID:32640989
A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function. PMID:32640256
Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene. PMID:32639993
The endosymbiont Wolbachia rebounds following antibiotic treatment. PMID:32639986
Advantages of an easy-to-use DNA extraction method for minimal-destructive analysis of collection specimens. PMID:32639972
Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission. PMID:32637955
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. PMID:32637944
Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer. PMID:32637350
A chromosome-scale reference genome of Aquilegia oxysepala var. kansuensis. PMID:32637141
Single-cell ATAC sequencing analysis: From data preprocessing to hypothesis generation. PMID:32637041
IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms. PMID:32636395
Discovery and population genomics of structural variation in a songbird genus. PMID:32636372
Low Oxygen Stress During Early Development Influences Regulation of Hypoxia-Response Genes in Farmed Atlantic Salmon (Salmo salar). PMID:32636218
Precipitation and vegetation shape patterns of genomic and craniometric variation in the central African rodent Praomys misonnei. PMID:32635865
Two New Putative Plant Viruses from Wood Metagenomics Analysis of an Esca Diseased Vineyard. PMID:32635154
A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program. PMID:32634384
Using urine to diagnose large-scale mtDNA deletions in adult patients. PMID:32634300
Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death. PMID:32634279
Genomic basis of homoploid hybrid speciation within chestnut trees. PMID:32632155
Pre-clinical study of induced pluripotent stem cell-derived dopaminergic progenitor cells for Parkinson's disease. PMID:32632153
Transcriptome Analyses of Candida albicans Biofilms, Exposed to Arachidonic Acid and Fluconazole, Indicates Potential Drug Targets. PMID:32631950
Cell type- and stage-specific expression of Otx2 is regulated by multiple transcription factors and cis-regulatory modules in the retina. PMID:32631829
Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing. PMID:32631448
Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experience. PMID:32631434
Mapping regulatory variants controlling gene expression in drought response and tolerance in maize. PMID:32631406
Genome-wide association analysis of canine T zone lymphoma identifies link to hypothyroidism and a shared association with mast-cell tumors. PMID:32631225
DUGMO: tool for the detection of unknown genetically modified organisms with high-throughput sequencing data for pure bacterial samples. PMID:32631215
IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network. PMID:32630447
An Economic Dilemma Between Molecular Weapon Systems May Explain an Arachno-atypical Venom in Wasp Spiders (Argiope bruennichi). PMID:32630016
Developmental origins of transgenerational sperm histone retention following ancestral exposures. PMID:32628935
Pyrrocidine, a molecular off switch for fumonisin biosynthesis. PMID:32628727
GSMN-ML- a genome scale metabolic network reconstruction of the obligate human pathogen Mycobacterium leprae. PMID:32628669
Technical Note on the quality of DNA sequencing for the molecular characterisation of genetically modified plants. PMID:32625981
Miocene Diversification in the Savannahs Precedes Tetraploid Rainforest Radiation in the African Tree Genus Afzelia (Detarioideae, Fabaceae). PMID:32625223
Degradative Capacity of Two Strains of Rhodonia placenta: From Phenotype to Genotype. PMID:32625194
An Unusual Salmonella Enteritidis Strain Carrying a Modified Virulence Plasmid Lacking the prot6e Gene Represents a Geographically Widely Distributed Lineage. PMID:32625191
Source Tracking Based on Core Genome SNV and CRISPR Typing of Salmonella enterica Serovar Heidelberg Isolates Involved in Foodborne Outbreaks in Québec, 2012. PMID:32625190
Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex. PMID:32620897
Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM. PMID:32620816
Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gene expression. PMID:32620123
Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. PMID:32619550
Genetic structure and insecticide resistance characteristics of fall armyworm populations invading China. PMID:32619331
Anti-inflammatory functions of the glucocorticoid receptor require DNA binding. PMID:32619221
Identification and characterisation of endogenous Avian Leukosis Virus subgroup E (ALVE) insertions in chicken whole genome sequencing data. PMID:32617122
Selective whole genome amplification of Plasmodium malariae DNA from clinical samples reveals insights into population structure. PMID:32616738
A novel pathogenic missense ADAMTS17 variant that impairs secretion causes Weill-Marchesani Syndrome with variably dysmorphic hand features. PMID:32616716
Genome Sequencing of a Severe Acute Respiratory Syndrome Coronavirus 2 Isolate Obtained from a South African Patient with Coronavirus Disease 2019. PMID:32616644
Genomic analysis of the domestication and post-Spanish conquest evolution of the llama and alpaca. PMID:32616020
Pleiotropic effects of RsmA and RsmE proteins in Pseudomonas fluorescens 2P24. PMID:32615927
Genomic characterization of the most barotolerant Listeria monocytogenes RO15 strain compared to reference strains used to evaluate food high pressure processing. PMID:32615922
Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity. PMID:32615027
Genomic analyses of multidrug-resistant Salmonella Indiana, Typhimurium, and Enteritidis isolates using MinION and MiSeq sequencing technologies. PMID:32614888
High genetic similarity between non-typhoidal Salmonella isolated from paired blood and stool samples of children in the Democratic Republic of the Congo. PMID:32614856
Transcriptomic Analysis of Human Mesenchymal Stem Cell Therapy in Incontinent Rat Injured Urethra. PMID:32614683
Poly(A) binding KPAF4/5 complex stabilizes kinetoplast mRNAs in Trypanosoma brucei. PMID:32614436
URMAP, an ultra-fast read mapper. PMID:32612885
The mitogenome portrait of Umbria in Central Italy as depicted by contemporary inhabitants and pre-Roman remains. PMID:32612271
Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion. PMID:32612238
Structure-seq2 probing of RNA structure upon amino acid starvation reveals both known and novel RNA switches in Bacillus subtilis. PMID:32611709
Comparison of Multiple Displacement Amplification (MDA) and Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) in Limited DNA Sequencing Based on Tube and Droplet. PMID:32610698
Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits. PMID:32610139
Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. PMID:32610040
Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment. PMID:32609822
Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae. PMID:32609810
Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication. PMID:32609721
"A cleaner break": Genetic divergence between geographic groups and sympatric phenotypes revealed in ballan wrasse (Labrus bergylta). PMID:32607218
Prior evolution in stochastic versus constant temperatures affects RNA virus evolvability at a thermal extreme. PMID:32607165
Genome-wide screening of microsatellites in golden snub-nosed monkey (Rhinopithecus roxellana), for the development of a standardized genetic marker system. PMID:32606319
Secondary Metabolism in the Gill Microbiota of Shipworms (Teredinidae) as Revealed by Comparison of Metagenomes and Nearly Complete Symbiont Genomes. PMID:32606027
The Genome Sequence of the Jean-Talon Strain, an Archeological Beer Yeast from Québec, Reveals Traces of Adaptation to Specific Brewing Conditions. PMID:32605927
MutantHuntWGS: A Pipeline for Identifying Saccharomyces cerevisiae Mutations. PMID:32605926
Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples. PMID:32605661
Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data. PMID:32605651
Genome assembly of the basket willow, Salix viminalis, reveals earliest stages of sex chromosome expansion. PMID:32605573
A structural UGDH variant associated with standard Munchkin cats. PMID:32605545
Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes. PMID:32605315
Ross River Virus Provokes Differentially Expressed MicroRNA and RNA Interference Responses in Aedes aegypti Mosquitoes. PMID:32605094
Discovery of Two Novel Negeviruses in a Dungfly Collected from the Arctic. PMID:32604989
Genetic Study in Korean Pediatric Patients with Steroid-Resistant Nephrotic Syndrome or Focal Segmental Glomerulosclerosis. PMID:32604935
Evaluation of the VISAGE Basic Tool for Appearance and Ancestry Prediction Using PowerSeq Chemistry on the MiSeq FGx System. PMID:32604780
Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs. PMID:32604718
Ancestral mitogenome capture of the Southeast Asian banded linsang. PMID:32603327
High mutation burden of circulating cell-free DNA in early-stage breast cancer patients is associated with a poor relapse-free survival. PMID:32602248
An inducible genome editing system for plants. PMID:32601420
Declining genetic diversity of European honeybees along the twentieth century. PMID:32601293
cnd-1/NeuroD1 Functions with the Homeobox Gene ceh-5/Vax2 and Hox Gene ceh-13/labial To Specify Aspects of RME and DD Neuron Fate in Caenorhabditis elegans. PMID:32601060
A novel stop-gain mutation in DPYS gene causing Dihidropyrimidinase deficiency, a case report. PMID:32600357
Structural variation of the malaria-associated human glycophorin A-B-E region. PMID:32600246
Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress. PMID:32599707
Gaussian mixture model-based unsupervised nucleotide modification number detection using nanopore-sequencing readouts. PMID:32597959
Bumblebee Workers Show Differences in Allele-Specific DNA Methylation and Allele-Specific Expression. PMID:32597949
OncotRF: an online resource for exploration of tRNA-derived fragments in human cancers. PMID:32597311
Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples. PMID:32597303
Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2. PMID:32596474
Fibrocyte accumulation in the lungs of cystic fibrosis patients. PMID:32593509
CONY: A Bayesian procedure for detecting copy number variations from sequencing read depths. PMID:32591545
Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms. PMID:32591390
A genome-wide survey of copy number variations reveals an asymmetric evolution of duplicated genes in rice. PMID:32591023
Whole-genome sequencing of European autochthonous and commercial pig breeds allows the detection of signatures of selection for adaptation of genetic resources to different breeding and production systems. PMID:32591011
Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes. PMID:32589964
An Activity-Mediated Transition in Transcription in Early Postnatal Neurons. PMID:32589877
The transcription factor Leu3 shows differential binding behavior in response to changing leucine availability. PMID:32589214
Characterization of Genetic and Allelic Diversity Amongst Cultivated and Wild Lentil Accessions for Germplasm Enhancement. PMID:32587602
Changes Introduced in the Open Reading Frame of Bovine Viral Diarrhea Virus During Serial Infection of Pregnant Swine. PMID:32587582
Quantitative trait loci and genes associated with salmonid alphavirus load in Atlantic salmon: implications for pancreas disease resistance and tolerance. PMID:32587341
CRISPR-Cas9 generated Pompe knock-in murine model exhibits early-onset hypertrophic cardiomyopathy and skeletal muscle weakness. PMID:32587263
Arctic-adapted dogs emerged at the Pleistocene-Holocene transition. PMID:32587022
Conservation and Divergence in Duplicated Fiber Coexpression Networks Accompanying Domestication of the Polyploid Gossypium hirsutum L. PMID:32586849
De Novo Genome Assemblies for Three North American Bumble Bee Species: Bombus bifarius, Bombus vancouverensis, and Bombus vosnesenskii. PMID:32586847
Interspecific analysis of diurnal gene regulation in panicoid grasses identifies known and novel regulatory motifs. PMID:32586356
Nascent Transcript Folding Plays a Major Role in Determining RNA Polymerase Elongation Rates. PMID:32585128
Relation between sex hormones and leucocyte telomere length in men with idiopathic pulmonary fibrosis. PMID:32583532
Negative dominance and dominance-by-dominance epistatic effects reduce grain-yield heterosis in wide crosses in wheat. PMID:32582844
Metabolic Engineering Strategies in Diatoms Reveal Unique Phenotypes and Genetic Configurations With Implications for Algal Genetics and Synthetic Biology. PMID:32582656
Tracing Back the Evolutionary Route of Enteroinvasive Escherichia coli (EIEC) and Shigella Through the Example of the Highly Pathogenic O96:H19 EIEC Clone. PMID:32582565
Corrigendum: Novel Meiotic miRNAs and Indications for a Role of PhasiRNAs in Meiosis. PMID:32582234
Robust Virome Profiling and Whole Genome Reconstruction of Viruses and Viroids Enabled by Use of Available mRNA and sRNA-Seq Datasets in Grapevine (Vitis vinifera L.). PMID:32582126
Pervasive lesion segregation shapes cancer genome evolution. PMID:32581361
Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development. PMID:32581223
cfNOMe - A single assay for comprehensive epigenetic analyses of cell-free DNA. PMID:32580754
Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis. PMID:32580699
Werewolf, There Wolf: Variants in Hairless Associated with Hypotrichia and Roaning in the Lykoi Cat Breed. PMID:32580512
Genetic Variants and Phenotypic Characteristics of Salmonella Typhimurium-Resistant Mutants after Exposure to Carvacrol. PMID:32580471
Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum. PMID:32580470
Transcriptome Analysis of Wounding in the Model Grass Lolium temulentum. PMID:32580425
Genome-Wide Identification of Discriminative Genetic Variations in Beef and Dairy Cattle via an Information-Theoretic Approach. PMID:32580275
Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss. PMID:32580135
Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation. PMID:32579954
The mutREAD method detects mutational signatures from low quantities of cancer DNA. PMID:32576827
Genome-Wide Increased Copy Number is Associated with Emergence of Dominant Clones of the Irish Potato Famine Pathogen Phytophthora infestans. PMID:32576669
A genomic view of trophic and metabolic diversity in clade-specific Lamellodysidea sponge microbiomes. PMID:32576248
Platelet-Released Growth Factors and Platelet-Rich Fibrin Induce Expression of Factors Involved in Extracellular Matrix Organization in Human Keratinocytes. PMID:32575800
A Genome-Wide Association Study Identifying Genetic Variants Associated with Growth, Carcass and Meat Quality Traits in Rabbits. PMID:32575740
A secreted LysM effector protects fungal hyphae through chitin-dependent homodimer polymerization. PMID:32574207
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. PMID:32572266
Regulation of Bacterial Cell Cycle Progression by Redundant Phosphatases. PMID:32571969
Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model. PMID:32571478
Whole genome characterization of autochthonous Bos taurus brachyceros and introduced Bos indicus indicus cattle breeds in Cameroon regarding their adaptive phenotypic traits and pathogen resistance. PMID:32571206
The role of introgression and ecotypic parallelism in delineating intraspecific conservation units. PMID:32567754
Expression profiling of microRNAs and isomiRs in conventional central chondrosarcoma. PMID:32566253
Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection. PMID:32566226
Germline mutations in MEN1 are associated with the tumorigenesis of pituitary adenoma associated with meningioma. PMID:32565981
Exploiting collateral sensitivity controls growth of mixed culture of sensitive and resistant cells and decreases selection for resistant cells in a cell line model. PMID:32565737
Analysis of structural variants in four African cichlids highlights an association with developmental and immune related genes. PMID:32564776
Genomic profiling of late-onset basal cell carcinomas from two brothers with nevoid basal cell carcinoma syndrome. PMID:32564428
Evaluation of CNV detection tools for NGS panel data in genetic diagnostics. PMID:32561899
Genomic signatures of domestication in Old World camels. PMID:32561887
A clinically and genomically annotated nerve sheath tumor biospecimen repository. PMID:32561749
Diauxie and co-utilization of carbon sources can coexist during bacterial growth in nutritionally complex environments. PMID:32561713
A chromosome-level assembly of the cat flea genome uncovers rampant gene duplication and genome size plasticity. PMID:32560686
Importance of Defluviitalea raffinosedens for Hydrolytic Biomass Degradation in Co-Culture with Hungateiclostridium thermocellum. PMID:32560349
Mutation of YL Results in a Yellow Leaf with Chloroplast RNA Editing Defect in Soybean. PMID:32560081
Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions. PMID:32559457
Resequencing of 297 melon accessions reveals the genomic history of improvement and loci related to fruit traits in melon. PMID:32559013
Evaluation of methods for detecting human reads in microbial sequencing datasets. PMID:32558637
Phenomics-based GWAS analysis reveals the genetic architecture for drought resistance in cotton. PMID:32558152
Mitochondrial protein biogenesis in the synapse is supported by local translation. PMID:32558077
Transcriptomes from German shepherd dogs reveal differences in immune activity between atopic dermatitis affected and control skin. PMID:32556497
IncC conjugative plasmids and SXT/R391 elements repair double-strand breaks caused by CRISPR-Cas during conjugation. PMID:32556263
Phylogenomics indicates the "living fossil" Isoetes diversified in the Cenozoic. PMID:32555586
A dynastic elite in monumental Neolithic society. PMID:32555485
Highly efficient synchronization of sheep skin fibroblasts at G2/M phase and isolation of sheep Y chromosomes by flow cytometric sorting. PMID:32555328
Genomic deregulation of PRMT5 supports growth and stress tolerance in chronic lymphocytic leukemia. PMID:32555249
Measles virus and rinderpest virus divergence dated to the sixth century BCE. PMID:32554594
Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato. PMID:32553272
Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons. PMID:32553182
Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development. PMID:32553173
Analysis of transcript-deleterious variants in Mendelian disorders: implications for RNA-based diagnostics. PMID:32552793
Actin-related protein Arp4 regulates euchromatic gene expression and development through H2A.Z deposition in blood-stage Plasmodium falciparum. PMID:32552779
Host plant genetic control of associated fungal and insect species in a Populus hybrid cross. PMID:32551087
Parallel flowering time clines in native and introduced ragweed populations are likely due to adaptation. PMID:32551046
Are shed hair genomes the most effective noninvasive resource for estimating relationships in the wild? PMID:32551045
fs(1)A13041 is a 5' UTR deletion of the essential gene small ovary in Drosophila. PMID:32550484
Two Cases of Vancomycin-Resistant Enterococcus faecium Bacteremia With Development of Daptomycin-Resistant Phenotype and its Detection Using Oxford Nanopore Sequencing. PMID:32550237
Revisiting the Taxonomic Synonyms and Populations of Saccharomyces cerevisiae-Phylogeny, Phenotypes, Ecology and Domestication. PMID:32549402
Extraction and Detection of Avian Influenza Virus From Wetland Sediment Using Enrichment-Based Targeted Resequencing. PMID:32548133
Whole exome sequencing identifies compound heterozygous variants of CR2 gene in monozygotic twin patients with common variable immunodeficiency. PMID:32547748
DeconPeaker, a Deconvolution Model to Identify Cell Types Based on Chromatin Accessibility in ATAC-Seq Data of Mixture Samples. PMID:32547592
Genotyping of Salmon Gill Poxvirus Reveals One Main Predominant Lineage in Europe, Featuring Fjord- and Fish Farm-Specific Sub-Lineages. PMID:32547516
Microevolution and Gain or Loss of Mobile Genetic Elements of Outbreak-Related Listeria monocytogenes in Food Processing Environments Identified by Whole Genome Sequencing Analysis. PMID:32547499
Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer. PMID:32546718
Association between bacterial homoplastic variants and radiological pathology in tuberculosis. PMID:32546574
Taro Genome Assembly and Linkage Map Reveal QTLs for Resistance to Taro Leaf Blight. PMID:32546503
Genomics of Clinal Local Adaptation in Pinus sylvestris Under Continuous Environmental and Spatial Genetic Setting. PMID:32546502
Environmental and Genetic Contributions to Imperfect wMel-Like Wolbachia Transmission and Frequency Variation. PMID:32546497
Catalogue of stage-specific transcripts in Ixodes ricinus and their potential functions during the tick life-cycle. PMID:32546252
3D genome architecture coordinates trans and cis regulation of differentially expressed ear and tassel genes in maize. PMID:32546248
Genome re-sequencing and reannotation of the Escherichia coli ER2566 strain and transcriptome sequencing under overexpression conditions. PMID:32546194
Lethal Outcome of Leptospirosis in Southern Russia: Characterization of Leptospira Interrogans Isolated from a Deсeased Teenager. PMID:32545855
Pleiotropic Functions of FoxN1: Regulating Different Target Genes during Embryogenesis and Nymph Molting in the Brown Planthopper. PMID:32545786
Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice. PMID:32544245
qDRIP: a method to quantitatively assess RNA-DNA hybrid formation genome-wide. PMID:32544226
Alterations in the Ocular Surface Microbiome in Traumatic Corneal Ulcer Patients. PMID:32543662
Genomic evidence for gene flow between monarchs with divergent migratory phenotypes and flight performance. PMID:32542770
Abundant expression of maternal siRNAs is a conserved feature of seed development. PMID:32541052
Analysis of oral microbiome from fossil human remains revealed the significant differences in virulence factors of modern and ancient Tannerella forsythia. PMID:32539695
Shifting evolutionary sands: transcriptome characterization of the Aptostichus atomarius species complex. PMID:32539685
Genomic Signatures of Local Adaptation in Clam Shrimp (Eulimnadia texana) from Natural Vernal Pools. PMID:32539143
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability. PMID:32533923
Mutations in virus-derived small RNAs. PMID:32533016
Increasing incidence of group B streptococcus neonatal infections in the Netherlands is associated with clonal expansion of CC17 and CC23. PMID:32533007
A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways. PMID:32532995
Ahr-Foxp3-RORγt axis controls gut homing of CD4+ T cells by regulating GPR15. PMID:32532834
Closing Human Reference Genome Gaps: Identifying and Characterizing Gap-Closing Sequences. PMID:32532800
Development and Validation of an Open Access SNP Array for Nile Tilapia (Oreochromis niloticus). PMID:32532799
Deconvolution of bulk blood eQTL effects into immune cell subpopulations. PMID:32532224
Genomic variation between PRSV resistant transgenic SunUp and its progenitor cultivar Sunset. PMID:32532215
Quantitative Trait Locus Mapping of Clubroot Resistance and Plasmodiophora brassicae Pathotype Banglim-Specific Marker Development in Brassica rapa. PMID:32532118
Vast Differences in Strain-Level Diversity in the Gut Microbiota of Two Closely Related Honey Bee Species. PMID:32531278
Xist Repeats A and B Account for Two Distinct Phases of X Inactivation Establishment. PMID:32531209
Minimum error correction-based haplotype assembly: Considerations for long read data. PMID:32530974
Genome-wide analysis of expression quantitative trait loci (eQTLs) reveals the regulatory architecture of gene expression variation in the storage roots of sweet potato. PMID:32528702
Comparative population genomics dissects the genetic basis of seven domestication traits in jujube. PMID:32528701
Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd (Momordica spp.). PMID:32528697
Identification of a Pathogenic TGFBR2 Variant in a Patient With Loeys-Dietz Syndrome. PMID:32528524
Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer. PMID:32527287
Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion. PMID:32527007
Bacsnp: Using Single Nucleotide Polymorphism (SNP) Specificities and Frequencies to Identify Genotype Composition in Baculoviruses. PMID:32526997
Novel Brown Coat Color (Cocoa) in French Bulldogs Results from a Nonsense Variant in HPS3. PMID:32526956
Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons. PMID:32526163
Ancient genome-wide DNA from France highlights the complexity of interactions between Mesolithic hunter-gatherers and Neolithic farmers. PMID:32523989
Honey Bee Suppresses the Parasitic Mite Vitellogenin by Antimicrobial Peptide. PMID:32523577
Faecal DNA to the rescue: Shotgun sequencing of non-invasive samples reveals two subspecies of Southeast Asian primates to be Critically Endangered species. PMID:32523128
Whole-genome sequencing provides new insights into genetic mechanisms of tropical adaptation in Nellore (Bos primigenius indicus). PMID:32523018
Whole genome sequence analysis reveals genetic structure and X-chromosome haplotype structure in indigenous Chinese pigs. PMID:32523001
Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats. PMID:32522985
Properties of structural variants and short tandem repeats associated with gene expression and complex traits. PMID:32522982
Notch-Mediated Generation of Monocyte-Derived Langerhans Cells: Phenotype and Function. PMID:32522485
Whole-genome sequencing of Chinese centenarians reveals important genetic variants in aging WGS of centenarian for genetic analysis of aging. PMID:32522283
Microtubule nucleation promoters Mto1 and Mto2 regulate cytokinesis in fission yeast. PMID:32520628
Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource. PMID:32519082
Shotgun sequencing of honey DNA can describe honey bee derived environmental signatures and the honey bee hologenome complexity. PMID:32518251
The genetic basis of sex determination in grapes. PMID:32518223
Alteromonas Myovirus V22 Represents a New Genus of Marine Bacteriophages Requiring a Tail Fiber Chaperone for Host Recognition. PMID:32518192
Draft genome sequence of antimicrobial producing Paenibacillus alvei strain MP1 reveals putative novel antimicrobials. PMID:32517793
Transcriptome-Based Analysis of Tomato Genotypes Resistant to Bacterial Spot (Xanthomonas perforans) Race T4. PMID:32517212
Identification of Regulatory SNPs Associated with Vicine and Convicine Content of Vicia faba Based on Genotyping by Sequencing Data Using Deep Learning. PMID:32516876
Folding Keratin Gene Clusters during Skin Regional Specification. PMID:32516596
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress. PMID:32516567
Copy Number Variation Detection Using Total Variation. PMID:32515750
Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs. PMID:32515737
The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer. PMID:32515734
Application of Whole-Genome Sequences and Machine Learning in Source Attribution of Salmonella Typhimurium. PMID:32515055
Determinants of genetic variation across eco-evolutionary scales in pinnipeds. PMID:32514167
CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response. PMID:32514124
Coexistence of genetically different Rhizophagus irregularis isolates induces genes involved in a putative fungal mating response. PMID:32514118
Changes in the transcriptome, ploidy, and optimal light intensity of a cryptomonad upon integration into a kleptoplastic dinoflagellate. PMID:32514116
Whole genome resequencing of four Italian sweet pepper landraces provides insights on sequence variation in genes of agronomic value. PMID:32514106
Novel XIAP mutation causing enhanced spontaneous apoptosis and disturbed NOD2 signalling in a patient with atypical adult-onset Crohn's disease. PMID:32514016
NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis. PMID:32513971
Chromosomal toxin-antitoxin systems in Pseudomonas putida are rather selfish than beneficial. PMID:32513960
Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor. PMID:32513869
Estimation of the Genome-Wide Mutation Rate and Spectrum in the Archaeal Species Haloferax volcanii. PMID:32513815
Complete plastome sequencing resolves taxonomic relationships among species of Calligonum L. (Polygonaceae) in China. PMID:32513105
Cancer of Unknown Primary (CUP): genetic evidence for a novel nosological entity? A case report. PMID:32511869
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium. PMID:32511382
Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions. PMID:32511352
Dynamic chromatin accessibility profiling reveals changes in host genome organization in response to baculovirus infection. PMID:32511266
A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay. PMID:32510323
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers. PMID:32510157
Genomic consequences of dietary diversification and parallel evolution due to nectarivory in leaf-nosed bats. PMID:32510151
Insights on early mutational events in SARS-CoV-2 virus reveal founder effects across geographical regions. PMID:32509472
Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections. PMID:32508793
Characterization of CYP26B1-Selective Inhibitor, DX314, as a Potential Therapeutic for Keratinization Disorders. PMID:32505549
Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing. PMID:32504042
Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica. PMID:32503977
Prefoldin-like Bud27 influences the transcription of ribosomal components and ribosome biogenesis in Saccharomyces cerevisiae. PMID:32503921
METHYLTRANSFERASE1 and Ripening Modulate Vivipary during Tomato Fruit Development. PMID:32503901
Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons. PMID:32503625
SnpHub: an easy-to-set-up web server framework for exploring large-scale genomic variation data in the post-genomic era with applications in wheat. PMID:32501478
Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress. PMID:32500975
Whole Genome and Transcriptome Sequencing of Two Multi-Drug Resistant Mycobacterium tuberculosis Strains to Facilitate Illustrating Their Virulence in vivo. PMID:32500039
MFCNV: A New Method to Detect Copy Number Variations From Next-Generation Sequencing Data. PMID:32499814
poly(UG)-tailed RNAs in genome protection and epigenetic inheritance. PMID:32499657
RIC-seq for global in situ profiling of RNA-RNA spatial interactions. PMID:32499643
ASCL1-regulated DARPP-32 and t-DARPP stimulate small cell lung cancer growth and neuroendocrine tumour cell proliferation. PMID:32499571
Whole-genome resequencing of wild and domestic sheep identifies genes associated with morphological and agronomic traits. PMID:32499537
Whole-Genome Sequences of Salmonella Isolates from an Ecological Wastewater Treatment System. PMID:32499355
Quantitative and Qualitative Perturbations of CD8+ MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals. PMID:32499216
High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down. PMID:32497496
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status. PMID:32497495
Potent, specific MEPicides for treatment of zoonotic staphylococci. PMID:32497104
An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons. PMID:32497040
Assessing the genomic relatedness and evolutionary rates of persistent verotoxigenic Escherichia coli serotypes within a closed beef herd in Canada. PMID:32496181
Phytoplankton pangenome reveals extensive prokaryotic horizontal gene transfer of diverse functions. PMID:32494685
Metagenomic growth rate inferences of strains in situ. PMID:32494636
Analysis of cell-associated DENV RNA by oligo(dT) primed 5' capture scRNAseq. PMID:32493997
The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice. PMID:32493987
The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis. PMID:32493925
Fusions involving BCOR and CREBBP are rare events in infiltrating glioma. PMID:32493417
LAMPS: an analysis pipeline for sequence-specific ligation-mediated amplification reads. PMID:32493406
A tissue level atlas of the healthy human virome. PMID:32493363
Regional Transmission and Reassortment of 2.3.4.4b Highly Pathogenic Avian Influenza (HPAI) Viruses in Bulgarian Poultry 2017/18. PMID:32492965
Functional Divergence of the Arabidopsis Florigen-Interacting bZIP Transcription Factors FD and FDP. PMID:32492426
Functional and Genomic Variation between Human-Derived Isolates of Lachnospiraceae Reveals Inter- and Intra-Species Diversity. PMID:32492369
Benchmark of software tools for prokaryotic chromosomal interaction domain identification. PMID:32492116
Study of Caspase 8 mutation in oral cancer and adjacent precancer tissues and implication in progression. PMID:32492030
One fly-one genome: chromosome-scale genome assembly of a single outbred Drosophila melanogaster. PMID:32491177
GFF Utilities: GffRead and GffCompare. PMID:32489650
All-in-one sequencing: an improved library preparation method for cost-effective and high-throughput next-generation sequencing. PMID:32489396
Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition. PMID:32488085
Supernumerary B chromosomes of Aegilops speltoides undergo precise elimination in roots early in embryo development. PMID:32488019
DAMEfinder: a method to detect differential allele-specific methylation. PMID:32487212
Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae. PMID:32487207
The Location of the Pseudoautosomal Boundary in Silene latifolia. PMID:32486434
A Novel Inducible Prophage from Burkholderia Vietnamiensis G4 is Widely Distributed across the Species and Has Lytic Activity against Pathogenic Burkholderia. PMID:32486377
Association of Common Genetic Variants in the CPSF7 and SDHAF2 Genes with Canine Idiopathic Pulmonary Fibrosis in the West Highland White Terrier. PMID:32486318
Lanthanide-Dependent Methanol and Formaldehyde Oxidation in Methylobacterium aquaticum Strain 22A. PMID:32486139
Mitogenomes Reveal Multiple Colonization of Mountains by Rattus in Sundaland. PMID:32485737
Structural and functional changes of gut microbiota in ovariectomized rats and their correlations with altered bone mass. PMID:32484785
Parallel reductive genome evolution in Desulfovibrio ectosymbionts independently acquired by Trichonympha protists in the termite gut. PMID:32483307
Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines. PMID:32483195
GLIS2 promotes colorectal cancer through repressing enhancer activation. PMID:32483180
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming. PMID:32483112
Genetic Mapping in Autohexaploid Sweet Potato with Low-Coverage NGS-Based Genotyping Data. PMID:32482727
CSI NGS Portal: An Online Platform for Automated NGS Data Analysis and Sharing. PMID:32481589
Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients. PMID:32479746
Regulatory sharing between estrogen receptor α bound enhancers. PMID:32479598
The origin of SARS-CoV-2 in Istanbul: Sequencing findings from the epicenter of the pandemic in Turkey. PMID:32478289
Long-Term Dynamics Among Wolbachia Strains During Thermal Adaptation of Their Drosophila melanogaster Hosts. PMID:32477411
Wheat Encodes Small, Secreted Proteins That Contribute to Resistance to Septoria Tritici Blotch. PMID:32477410
Genomic and Phenotypic Heterogeneity of Clinical Isolates of the Human Pathogens Aspergillus fumigatus, Aspergillus lentulus, and Aspergillus fumigatiaffinis. PMID:32477406
The Evolution of an Invasive Plant, Sorghum halepense L. ('Johnsongrass'). PMID:32477397
Identification of Selective Sweeps in the Domesticated Table and Wine Grape (Vitis vinifera L.). PMID:32477387
Identification of a Rare PSEN1 Mutation (Thr119Ile) in Late-Onset Alzheimer's Disease With Early Presentation of Behavioral Disturbance. PMID:32477171
A quantitative trait locus on chromosome 2 was identified that accounts for a substantial proportion of phenotypic variance of the yellow plumage color in chicken. PMID:32475423
Clonal lineage from normal endometrium to ovarian clear cell carcinoma through ovarian endometriosis. PMID:32473611
Evolution and structure of clinically relevant gene fusions in multiple myeloma. PMID:32471990
Searching for a Bacteriophage Lysin to Treat Corynebacterium bovis in Immunocompromised Mice. PMID:32471521
Functional insights from the GC-poor genomes of two aphid parasitoids, Aphidius ervi and Lysiphlebus fabarum. PMID:32471448
Characterization and Analysis of the Mitochondrial Genome of Common Bean (Phaseolus vulgaris) by Comparative Genomic Approaches. PMID:32471098
Hi-C Identifies Complex Genomic Rearrangements and TAD-Shuffling in Developmental Diseases. PMID:32470376
H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect. PMID:32470364
Fcirc: A comprehensive pipeline for the exploration of fusion linear and circular RNAs. PMID:32470133
Uneven Missing Data Skew Phylogenomic Relationships within the Lories and Lorikeets. PMID:32470111
Sevoflurane depletes macrophages from the melanoma microenvironment. PMID:32470095
Association of microtubules and axonal RNA transferred from myelinating Schwann cells in rat sciatic nerve. PMID:32469980
A transcriptome-based approach to identify functional modules within and across primary human immune cells. PMID:32469933
Global changes in nitration levels and DNA binding profile of Trypanosoma cruzi histones induced by incubation with host extracellular matrix. PMID:32469928
Spatial inter-centromeric interactions facilitated the emergence of evolutionary new centromeres. PMID:32469306
Transcriptome-Wide Comparisons and Virulence Gene Polymorphisms of Host-Associated Genotypes of the Cnidarian Parasite Ceratonova shasta in Salmonids. PMID:32467979
Dental Calculus as a Tool to Study the Evolution of the Mammalian Oral Microbiome. PMID:32467975
De Novo Genome Assembly of Limpet Bathyacmaea lactea (Gastropoda: Pectinodontidae): The First Reference Genome of a Deep-Sea Gastropod Endemic to Cold Seeps. PMID:32467969
Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification. PMID:32467243
NIPT Technique Based on the Use of Long Chimeric DNA Reads. PMID:32466452
Mask, a component of the Hippo pathway, is required for Drosophila eye morphogenesis. PMID:32464117
Exome-wide association study reveals largely distinct gene sets underlying specific resistance to dengue virus types 1 and 3 in Aedes aegypti. PMID:32463828
mmannot: How to improve small-RNA annotation? PMID:32463818
PolyA-miner: accurate assessment of differential alternative poly-adenylation from 3'Seq data using vector projections and non-negative matrix factorization. PMID:32463457
fRNAkenseq: a fully powered-by-CyVerse cloud integrated RNA-sequencing analysis tool. PMID:32461821
The stepwise assembly of the neonatal virome is modulated by breastfeeding. PMID:32461640
Integrative analysis of reference epigenomes in 20 rice varieties. PMID:32461553
Synergistic CRISPRa-Regulated Chondrogenic Extracellular Matrix Deposition Without Exogenous Growth Factors. PMID:32460686
CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia. PMID:32460032
A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging. PMID:32460027
Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut microbiome. PMID:32459982
Epigenetic inheritance of circadian period in clonal cells. PMID:32459177
Investigation of Plasma cell-free cancer genome chromosomal instability as a tool for targeted minimally invasive biomarkers for primary liver cancer diagnoses. PMID:32458568
The Genomic Characteristics of ALK Fusion Positive Tumors in Chinese NSCLC Patients. PMID:32457845
Analysis of the Mouse Y Chromosome by Single-Molecule Sequencing With Y Chromosome Enrichment. PMID:32457799
Integrative Omics Analysis Reveals a Limited Transcriptional Shock After Yeast Interspecies Hybridization. PMID:32457798
The Mitochondrial Genome of the Phytopathogenic Fungus Bipolaris sorokiniana and the Utility of Mitochondrial Genome to Infer Phylogeny of Dothideomycetes. PMID:32457727
Elizabethkingia anophelis: Physiologic and Transcriptomic Responses to Iron Stress. PMID:32457715
NHJ-1 Is Required for Canonical Nonhomologous End Joining in Caenorhabditis elegans. PMID:32457132
Transcriptome profiling of porcine testis tissue reveals genes related to sperm hyperactive motility. PMID:32456687
ARTDeco: automatic readthrough transcription detection. PMID:32456667
Superior haplotypes for haplotype-based breeding for drought tolerance in pigeonpea (Cajanus cajan L.). PMID:32455481
Pangenome Graphs. PMID:32453966
Candidate gene expression and coding sequence variants in Warmblood horses with myofibrillar myopathy. PMID:32453872
QTL-seq identifies BnaFT.A02 and BnaFLC.A02 as candidates for variation in vernalization requirement and response in winter oilseed rape (Brassica napus). PMID:32452611
A molecular filter for the cnidarian stinging response. PMID:32452384
Convergent molecular evolution among ash species resistant to the emerald ash borer. PMID:32451426
Recent introgression between Taiga Bean Goose and Tundra Bean Goose results in a largely homogeneous landscape of genetic differentiation. PMID:32451423
Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest. PMID:32451414
The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes. PMID:32451402
Personalized and graph genomes reveal missing signal in epigenomic data. PMID:32450900
Mosquito-borne viruses, insect-specific flaviviruses (family Flaviviridae, genus Flavivirus), Banna virus (family Reoviridae, genus Seadornavirus), Bogor virus (unassigned member of family Permutotetraviridae), and alphamesoniviruses 2 and 3 (family Mesoniviridae, genus Alphamesonivirus) isolated from Indonesian mosquitoes. PMID:32448813
PACVr: plastome assembly coverage visualization in R. PMID:32448146
Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion. PMID:32447260
Research Techniques Made Simple: Whole-Transcriptome Sequencing by RNA-Seq for Diagnosis of Monogenic Disorders. PMID:32446329
Opposing Functions of BRD4 Isoforms in Breast Cancer. PMID:32446320
Transcriptional activation during cell reprogramming correlates with the formation of 3D open chromatin hubs. PMID:32444798
Germline Mutation in MUS81 Resulting in Impaired Protein Stability is Associated with Familial Breast and Thyroid Cancer. PMID:32443704
Distinct Mechanisms of Resistance to a CENP-E Inhibitor Emerge in Near-Haploid and Diploid Cancer Cells. PMID:32442423
Metagenome Assembly and Metagenome-Assembled Genome Sequences from a Historical Oil Field Located in Wietze, Germany. PMID:32439669
UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide. PMID:32439635
The microbiome as a biosensor: functional profiles elucidate hidden stress in hosts. PMID:32438915
A Reference Genome of Bursaphelenchus mucronatus Provides New Resources for Revealing Its Displacement by Pinewood Nematode. PMID:32438771
Examining Short-Term Responses to a Long-Term Problem: RNA-Seq Analyses of Iron Deficiency Chlorosis Tolerant Soybean. PMID:32438745
SCOPE: A Normalization and Copy-Number Estimation Method for Single-Cell DNA Sequencing. PMID:32437686
Fine-Scale Position Effects Shape the Distribution of Inversion Breakpoints in Drosophila melanogaster. PMID:32437518
iWhale: a computational pipeline based on Docker and SCons for detection and annotation of somatic variants in cancer WES data. PMID:32436933
Viral infection impacts transposable element transcript amounts in Drosophila. PMID:32434916
Gapless assembly of maize chromosomes using long-read technologies. PMID:32434565
Impacts of local population history and ecology on the evolution of a globally dispersed pathogen. PMID:32434538
Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer. PMID:32434218
Viral and host factors related to the clinical outcome of COVID-19. PMID:32434211
Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing. PMID:32433965
Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons. PMID:32433963
Pig-specific RNA editing during early embryo development revealed by genome-wide comparisons. PMID:32433824
Chromosomal-Level Genome Assembly of the Sea Urchin Lytechinus variegatus Substantially Improves Functional Genomic Analyses. PMID:32433766
MinION Sequencing of colorectal cancer tumour microbiomes-A comparison with amplicon-based and RNA-Sequencing. PMID:32433701
Initial Upper Palaeolithic Homo sapiens from Bacho Kiro Cave, Bulgaria. PMID:32433609
Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with Lynch syndrome like metastatic colorectal cancer. PMID:32432717
Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity. PMID:32432546
High-quality chromosome-scale assembly of the walnut (Juglans regia L.) reference genome. PMID:32432329
Metagenomic Diagnosis for a Culture-Negative Sample From a Patient With Severe Pneumonia by Nanopore and Next-Generation Sequencing. PMID:32432051
Fine-scale barriers to connectivity across a fragmented South-East Asian landscape in six songbird species. PMID:32431750
A comparison of pedigree, genetic and genomic estimates of relatedness for informing pairing decisions in two critically endangered birds: Implications for conservation breeding programmes worldwide. PMID:32431748
Retrograde Induction of phyB Orchestrates Ethylene-Auxin Hierarchy to Regulate Growth. PMID:32430463
Epigenetic Regulation of Alternative mRNA Splicing in Dilated Cardiomyopathy. PMID:32429430
SinoDuplex: An Improved Duplex Sequencing Approach to Detect Low-frequency Variants in Plasma cfDNA Samples. PMID:32428603
Genome Assembly of the Ragweed Leaf Beetle: A Step Forward to Better Predict Rapid Evolution of a Weed Biocontrol Agent to Environmental Novelties. PMID:32428241
Phylogenetic analysis of the Y-chromosome haplogroup C2b-F1067, a dominant paternal lineage in Eastern Eurasia. PMID:32427951
HOX13-dependent chromatin accessibility underlies the transition towards the digit development program. PMID:32427842
ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin. PMID:32427330
Guppy Y Chromosome Integrity Maintained by Incomplete Recombination Suppression. PMID:32426836
Identification of nodulation-related genes in Medicago truncatula using genome-wide association studies and co-expression networks. PMID:32426691
Defined lifestyle and germline factors predispose Asian populations to gastric cancer. PMID:32426482
Accurate Inference of Tumor Purity and Absolute Copy Numbers From High-Throughput Sequencing Data. PMID:32425990
Review: Understanding Rare Genetic Diseases in Low Resource Regions Like Jammu and Kashmir - India. PMID:32425985
Isolation of a Male-Specific Molecular Marker and Development of a Genetic Sex Identification Technique in Spotted Knifejaw (Oplegnathus punctatus). PMID:32424478
Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases. PMID:32424352
The genome of Mekong tiger perch (Datnioides undecimradiatus) provides insights into the phylogenetic position of Lobotiformes and biological conservation. PMID:32424221
Polymorphic centromere locations in the pathogenic yeast Candida parapsilosis. PMID:32424070
RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function. PMID:32423473
Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse. PMID:32423436
Identification of Upstream Transcriptional Regulators of Ischemic Cardiomyopathy Using Cardiac RNA-Seq Meta-Analysis. PMID:32423033
Uterine infection alters the transcriptome of the bovine reproductive tract three months later. PMID:32422601
Comprehensive Characterization of the Mutational Landscape in Localized Anal Squamous Cell Carcinoma. PMID:32422573
The G123 rice mutant, carrying a mutation in SE13, presents alterations in the expression patterns of photosynthetic and major flowering regulatory genes. PMID:32421736
Identification and Analysis of Estrogen Receptor α Promoting Tamoxifen Resistance-Related lncRNAs. PMID:32420379
Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. PMID:32416067
Design principles of a minimal auxin response system. PMID:32415296
Homoplastic single nucleotide polymorphisms contributed to phenotypic diversity in Mycobacterium tuberculosis. PMID:32415151
Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours. PMID:32415113
The F-Box-Like Protein FBL17 Is a Regulator of DNA-Damage Response and Colocalizes with RETINOBLASTOMA RELATED1 at DNA Lesion Sites. PMID:32414898
A Multimodal Genotoxic Anticancer Drug Characterized by Pharmacogenetic Analysis in Caenorhabditis elegans. PMID:32414869
Biased Gene Conversion Constrains Adaptation in Arabidopsis thaliana. PMID:32414868
Linking Virus Discovery to Immune Responses Visualized during Zebrafish Infections. PMID:32413307
Design and Experimental Evaluation of a Minimal, Innocuous Watermarking Strategy to Distinguish Near-Identical DNA and RNA Sequences. PMID:32413257
High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda. PMID:32413052
Whole exome sequencing in patients with Williams-Beuren syndrome followed by disease modeling in mice points to four novel pathways that may modify stenosis risk. PMID:32412588
Integrative analysis of DNA methylation and gene expression profiles identified potential breast cancer-specific diagnostic markers. PMID:32412047
Tracking echovirus eleven outbreaks in Guangdong, China: a metatranscriptomic, phylogenetic, and epidemiological study. PMID:32411392
Chromosome-Scale Assembly of Winter Oilseed Rape Brassica napus. PMID:32411167
Hepatic Transcriptome Analysis Identifies Divergent Pathogen-Specific Targeting-Strategies to Modulate the Innate Immune System in Response to Intramammary Infection. PMID:32411137
Investigation of a Salmonellosis Outbreak Caused by Multidrug Resistant Salmonella Typhimurium in China. PMID:32411120
Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells. PMID:32410854
Genome-wide variations analysis of sorghum cultivar Hongyingzi for brewing Moutai liquor. PMID:32410666
Whole-Genome Sequences of Three Plant Growth-Promoting Rhizobacteria Isolated from Solanum tuberosum L. Rhizosphere in Tanzania. PMID:32409546
Phased Diploid Genome Sequence for the Fast-Growing Microalga Picochlorum celeri. PMID:32409528
Convergent Loss of an EDS1/PAD4 Signaling Pathway in Several Plant Lineages Reveals Coevolved Components of Plant Immunity and Drought Response. PMID:32409319
Emerging Roles for 3' UTRs in Neurons. PMID:32408514
MCH Neurons Regulate Permeability of the Median Eminence Barrier. PMID:32407670
Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients. PMID:32407669
Dynamics of the Stool Virome in Very Early-Onset Inflammatory Bowel Disease. PMID:32406906
YAP1/TAZ drives ependymoma-like tumour formation in mice. PMID:32404936
Extreme Viral Partitioning in a Marine-Derived High Arctic Lake. PMID:32404515
Genomic studies on Strongyloides stercoralis in northern and western Thailand. PMID:32404172
Investigating Human Mitochondrial Genomes in Single Cells. PMID:32403285
KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs. PMID:32402252
Drosophila histone locus body assembly and function involves multiple interactions. PMID:32401666
Mitochondrial DNA alterations may influence the cisplatin responsiveness of oral squamous cell carcinoma. PMID:32398775
Detection of low-frequency resistance-mediating SNPs in next-generation sequencing data of Mycobacterium tuberculosis complex strains with binoSNP. PMID:32398743
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. PMID:32396847
Extreme genomic volatility characterizes the evolution of the immunoglobulin heavy chain locus in cyprinodontiform fishes. PMID:32396805
Oligocene divergence of frogmouth birds (Podargidae) across Wallace's Line. PMID:32396783
A de novo chromosome-level genome assembly of Coregonus sp. "Balchen": One representative of the Swiss Alpine whitefish radiation. PMID:32395896
SUMOylated PRC1 controls histone H3.3 deposition and genome integrity of embryonic heterochromatin. PMID:32395866
A bioinformatic pipeline to analyze ChIP-exo datasets. PMID:32395628
Pervasive and non-random recombination in near full-length HIV genomes from Uganda. PMID:32395255
Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin. PMID:32393884
Somatic genetic drift and multilevel selection in a clonal seagrass. PMID:32393866
ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms. PMID:32393825
Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis. PMID:32393644
Repeat RNAs associate with replication forks and post-replicative DNA. PMID:32393525
The seasonal development dynamics of the yak hair cycle transcriptome. PMID:32393236
Comparative Analysis of Root Transcriptome Reveals Candidate Genes and Expression Divergence of Homoeologous Genes in Response to Water Stress in Wheat. PMID:32392904
Oviz-Bio: a web-based platform for interactive cancer genomics data visualization. PMID:32392343
Depletion of Ric-8B leads to reduced mTORC2 activity. PMID:32392211
Polyploidy breaks speciation barriers in Australian burrowing frogs Neobatrachus. PMID:32392206
Genetic Variability of 3'-Proximal Region of Genomes of Orf Viruses Isolated From Sheep and Wild Japanese Serows (Capricornis crispus) in Japan. PMID:32391386
Identifying Candida albicans Gene Networks Involved in Pathogenicity. PMID:32391057
Lachancea fermentati Strains Isolated From Kombucha: Fundamental Insights, and Practical Application in Low Alcohol Beer Brewing. PMID:32390994
Carbon monoxide-dependent transcriptional changes in a thermophilic, carbon monoxide-utilizing, hydrogen-evolving bacterium Calderihabitans maritimus KKC1 revealed by transcriptomic analysis. PMID:32388815
Unblending of Transcriptional Condensates in Human Repeat Expansion Disease. PMID:32386547
A Paleogenomic Reconstruction of the Deep Population History of the Andes. PMID:32386546
Budding yeast complete DNA synthesis after chromosome segregation begins. PMID:32385287
Effect of sequence depth and length in long-read assembly of the maize inbred NC358. PMID:32385271
Chromosome-level assembly of the horseshoe crab genome provides insights into its genome evolution. PMID:32385269
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. PMID:32385263
Improving the Chromosome-Level Genome Assembly of the Siamese Fighting Fish (Betta splendens) in a University Master's Course. PMID:32385046
The loss of photosynthesis pathway and genomic locations of the lost plastid genes in a holoparasitic plant Aeginetia indica. PMID:32384868
APC Mutation Marks an Aggressive Subtype of BRAF Mutant Colorectal Cancers. PMID:32384699
Identification and Annotation of Potential Function of Regulatory Antisense Long Non-Coding RNAs Related to Feed Efficiency in Bos taurus Bulls. PMID:32384694
Comprehensive analysis of mutations of renal cell carcinoma in an autosomal dominant polycystic kidney disease patient. PMID:32384474
Split & mix assembly of DNA libraries for ultrahigh throughput on-bead screening of functional proteins. PMID:32383757
A novel variant of the IFITM5 gene within the 5'-UTR causes neonatal transverse clavicular fracture: Expanding the genetic spectrum. PMID:32383316
Tracking Neoantigens by Personalized Circulating Tumor DNA Sequencing during Checkpoint Blockade Immunotherapy in Non-Small Cell Lung Cancer. PMID:32382482
Discovery of alternative polyadenylation dynamics from single cell types. PMID:32382395
Transcriptional down-regulation of metabolic genes by Gdown1 ablation induces quiescent cell re-entry into the cell cycle. PMID:32381628
Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line. PMID:32380717
A Modular Metagenomics Pipeline Allowing for the Inclusion of Prior Knowledge Using the Example of Anaerobic Digestion. PMID:32380653
intansv: an R package for integrative analysis of structural variations. PMID:32377445
Genetic diversity, population structure, and relationships of apricot (Prunus) based on restriction site-associated DNA sequencing. PMID:32377359
The transcription factor GLI1 cooperates with the chromatin remodeler SMARCA2 to regulate chromatin accessibility at distal DNA regulatory elements. PMID:32376693
Kaposi's Sarcoma-Associated Herpesvirus Fine-Tunes the Temporal Expression of Late Genes by Manipulating a Host RNA Quality Control Pathway. PMID:32376621
Host gill attachment causes blood-feeding by the salmon louse (Lepeophtheirus salmonis) chalimus larvae and alters parasite development and transcriptome. PMID:32375890
The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis. PMID:32375885
Genomic evidence for a hybrid origin of the yeast opportunistic pathogen Candida albicans. PMID:32375762
Identification of functional mutations associated with environmental variance of litter size in rabbits. PMID:32375645
Mycobacterium bovis: From Genotyping to Genome Sequencing. PMID:32375210
Elicitation with Bacillus QV15 reveals a pivotal role of F3H on flavonoid metabolism improving adaptation to biotic stress in blackberry. PMID:32374762
Transcriptome of the parasitic flatworm Schistosoma mansoni during intra-mammalian development. PMID:32374726
The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair. PMID:32374261
Genotypic and Phenotypic Characterization of Fecal Staphylococcus epidermidis Isolates Suggests Plasticity to Adapt to Different Human Body Sites. PMID:32373098
Assessing Population Diversity of Brettanomyces Yeast Species and Identification of Strains for Brewing Applications. PMID:32373090
Development of a new macrophage-specific TRAP mouse (MacTRAP) and definition of the renal macrophage translational signature. PMID:32372032
Genome sequence analysis of multidrug-resistant Mycobacterium tuberculosis from Malaysia. PMID:32371951
Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming. PMID:32371941
Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues. PMID:32371927
Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. PMID:32371905
Genomic differentiation and intercontinental population structure of mosquito vectors Culex pipiens pipiens and Culex pipiens molestus. PMID:32371903
Early Assessment of Molecular Progression and Response by Whole-genome Circulating Tumor DNA in Advanced Solid Tumors. PMID:32371589
Isolation and Characterization of the Novel Phage JD032 and Global Transcriptomic Response during JD032 Infection of Clostridioides difficile Ribotype 078. PMID:32371470
Epidermal growth factor receptor-dependent DNA repair promotes murine and human hematopoietic regeneration. PMID:32369572
Prediction of miRNA targets by learning from interaction sequences. PMID:32369518
Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma. PMID:32369491
Genome-wide assessment of population structure and genetic diversity of Chinese Lou onion using specific length amplified fragment (SLAF) sequencing. PMID:32369481
MaRe: Processing Big Data with application containers on Apache Spark. PMID:32369166
Controlling gene activation by enhancers through a drug-inducible topological insulator. PMID:32369019
Non-invasive prediction of fetal growth restriction by whole-genome promoter profiling of maternal plasma DNA: a nested case-control study. PMID:32364311
Mutations in MC4R facilitate the angiogenic activity in patients with orbital venous malformation. PMID:32363922
Needlestack: an ultra-sensitive variant caller for multi-sample next generation sequencing data. PMID:32363341
Next Generation Sequencing Assay for Detection of Circulating HPV DNA (cHPV-DNA) in Patients Undergoing Radical (Chemo)Radiotherapy in Anal Squamous Cell Carcinoma (ASCC). PMID:32363162
Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines. PMID:32362655
Genomic Epidemiology of SARS-CoV-2 in Guangdong Province, China. PMID:32359424
Selection following Gene Duplication Shapes Recent Genome Evolution in the Pea Aphid Acyrthosiphon pisum. PMID:32359152
Pervasive Phenotypic Impact of a Large Nonrecombining Introgressed Region in Yeast. PMID:32359150
Understanding the Early Evolutionary Stages of a Tandem Drosophilamelanogaster-Specific Gene Family: A Structural and Functional Population Study. PMID:32359138
Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone. PMID:32358570
Mutational signatures are jointly shaped by DNA damage and repair. PMID:32358516
The Set1 N-terminal domain and Swd2 interact with RNA polymerase II CTD to recruit COMPASS. PMID:32358498
Recent hybrids recapitulate ancient hybrid outcomes. PMID:32358487
YM155-Adapted Cancer Cell Lines Reveal Drug-Induced Heterogeneity and Enable the Identification of Biomarker Candidates for the Acquired Resistance Setting. PMID:32357518
Mutagenic Effect of Three Ion Beams on Rice and Identification of Heritable Mutations by Whole Genome Sequencing. PMID:32357388
Genotyping by multiplexed sequencing (GMS): A customizable platform for genomic selection. PMID:32357171
Genetic basis for virulence differences of various Cryptosporidium parvum carcinogenic isolates. PMID:32355272
Replication analysis of variants associated with multiple sclerosis risk. PMID:32355262
Complete Genome Sequence of Helicobacter pylori Strain ATCC 43504, a Type Strain That Can Infect Gerbils. PMID:32354967
Germline variant in REXO2 is a novel candidate gene in familial pheochromocytoma. PMID:32354376
Identification of triple-negative breast cancer cell lines classified under the same molecular subtype using different molecular characterization techniques: Implications for translational research. PMID:32353087
Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice. PMID:32352380
Extensive Inter-Cyst DNA Methylation Variation in Autosomal Dominant Polycystic Kidney Disease Revealed by Genome Scale Sequencing. PMID:32351541
Genomic Investigation of the Strawberry Pathogen Phytophthora fragariae Indicates Pathogenicity Is Associated With Transcriptional Variation in Three Key Races. PMID:32351458
Development of co-dominant markers linked to a hemizygous region that is related to the self-compatibility locus (S) in buckwheat (Fagopyrum esculentum). PMID:32351310
Simultaneous quantification of protein-DNA interactions and transcriptomes in single cells with scDam&T-seq. PMID:32350457
Reference exome data for Australian Aboriginal populations to support health-based research. PMID:32350262
LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. PMID:32350257
Synthetic hybrids of six yeast species. PMID:32350251
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle. PMID:32350247
Under-the-Radar Dengue Virus Infections in Natural Populations of Aedes aegypti Mosquitoes. PMID:32350095
Genome-wide analysis on the maize genome reveals weak selection on synonymous mutations. PMID:32349669
Combined neurodevelopmental exposure to deltamethrin and corticosterone is associated with Nr3c1 hypermethylation in the midbrain of male mice. PMID:32348866
Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection. PMID:32348760
Adaptive Introgression across Semipermeable Species Boundaries between Local Helicoverpa zea and Invasive Helicoverpa armigera Moths. PMID:32348505
Resistance-Conferring Mutations on Whole-Genome Sequencing of Fluoroquinolone-resistant and -Susceptible Mycobacterium tuberculosis Isolates: A Proposed Threshold for Identifying Resistance. PMID:32348473
VSeq-Toolkit: Comprehensive Computational Analysis of Viral Vectors in Gene Therapy. PMID:32346552
Genomic Epidemiology of an Outbreak of Klebsiella pneumoniae ST471 Producing Extended-Spectrum β-Lactamases in a Neonatal Intensive Care Unit. PMID:32346299
Targeted conservation genetics of the endangered chimpanzee. PMID:32346130
Extracellular electron transfer-dependent anaerobic oxidation of ammonium by anammox bacteria. PMID:32345973
Improved bacterial RNA-seq by Cas9-based depletion of ribosomal RNA reads. PMID:32345633
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues. PMID:32345368
Varlociraptor: enhancing sensitivity and controlling false discovery rate in somatic indel discovery. PMID:32345333
Mimicry diversification in Papilio dardanus via a genomic inversion in the regulatory region of engrailed-invected. PMID:32345166
Methodological differences can affect sequencing depth with a possible impact on the accuracy of genetic diagnosis. PMID:32343762
"Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence. PMID:32343693
Genome-wide selection and genetic improvement during modern maize breeding. PMID:32341525
Allelic polymorphism shapes community function in evolving Pseudomonas aeruginosa populations. PMID:32341475
Identification of an unauthorized genetically modified bacteria in food enzyme through whole-genome sequencing. PMID:32341433
Dynamics of Global Gene Expression and Regulatory Elements in Growing Brachypodium Root System. PMID:32341392
Putting the microbiota to work: Epigenetic effects of early life antibiotic treatment are associated with immune-related pathways and reduced epithelial necrosis following Salmonella Typhimurium challenge in vitro. PMID:32339193
Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus. PMID:32338592
rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments. PMID:32338139
Kinome multigenic panel identified novel druggable EPHB4-V871I somatic variant in high-risk neuroblastoma. PMID:32336043
GATA2 and Progesterone Receptor Interaction in Endometrial Stromal Cells Undergoing Decidualization. PMID:32335672
Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. PMID:32333827
Mapping the spreading routes of lymphatic metastases in human colorectal cancer. PMID:32332722
Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis. PMID:32330456
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor. PMID:32330454
Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. PMID:32329713
Metagenomic analysis of the human microbiome reveals the association between the abundance of gut bile salt hydrolases and host health. PMID:32329665
A detailed characteristics of bias associated with long runs of homozygosity identification based on medium density SNP microarrays. PMID:32328205
Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production. PMID:32327653
Sex chromosome evolution in parasitic nematodes of humans. PMID:32327641
Long-term isolation of European steppe outposts boosts the biome's conservation value. PMID:32327640
Complete Genome Sequences of Two Cutibacterium acnes Strains Isolated from an Orthopedic Surgical Site. PMID:32327511
Population Connectivity and Genetic Assessment of Exploited and Natural Populations of Pearl Oysters within a French Polynesian Atoll Lagoon. PMID:32326599
Genomic diversity of the human pathogen Paracoccidioides across the South American continent. PMID:32325168
Genome diversity and evolutionary characteristics of clinical isolates of Bordetella pertussis circulating in Iran. PMID:32322373
Mapping co-ancestry connections between the genome of a Medieval individual and modern Europeans. PMID:32321996
Development of new genetic resources for faba bean (Vicia faba L.) breeding through the discovery of gene-based SNP markers and the construction of a high-density consensus map. PMID:32321933
Consistent RNA sequencing contamination in GTEx and other data sets. PMID:32321923
BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks. PMID:32321568
Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism. PMID:32320661
Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities. PMID:32320644
Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq. PMID:32320643
Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation. PMID:32319885
Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance. PMID:32319721
Effect for Human Genomic Variation During the BMP4-Induced Conversion From Pluripotent Stem Cells to Trophoblast. PMID:32318089
Suppressor mutations in Mecp2-null mice implicate the DNA damage response in Rett syndrome pathology. PMID:32317254
Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma. PMID:32317009
Orthohantavirus Isolated in Reservoir Host Cells Displays Minimal Genetic Changes and Retains Wild-Type Infection Properties. PMID:32316667
De Novo Transcriptome Assembly and Annotation of Liver and Brain Tissues of Common Brushtail Possums (Trichosurus vulpecula) in New Zealand: Transcriptome Diversity after Decades of Population Control. PMID:32316496
Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing. PMID:32316399
Enabling large-scale genome editing at repetitive elements by reducing DNA nicking. PMID:32315033
Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP. PMID:32314924
A "One-Health" approach for diagnosis and molecular characterization of SARS-CoV-2 in Italy. PMID:32313828
Canadian polar bear population structure using genome-wide markers. PMID:32313629
Identification of Gastrointestinal Microbiota in Hawaiian Green Turtles (Chelonia mydas). PMID:32313421
First comprehensive TSC1/TSC2 mutational analysis in Mexican patients with Tuberous Sclerosis Complex reveals numerous novel pathogenic variants. PMID:32313033
Dual functionality of the amyloid protein TasA in Bacillus physiology and fitness on the phylloplane. PMID:32313019
Heat stress-induced transposon activation correlates with 3D chromatin organization rearrangement in Arabidopsis. PMID:32312999
Complete characterization of the human immune cell transcriptome using accurate full-length cDNA sequencing. PMID:32312742
The evolutionary history and genomics of European blackcap migration. PMID:32312383
scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data. PMID:32312293
Transcriptome analysis of responses in Brachypodium distachyon overexpressing the BdbZIP26 transcription factor. PMID:32312226
Genomic analysis of natural intra-specific hybrids among Ethiopian isolates of Leishmania donovani. PMID:32310945
Discovery of novel hepatocyte eQTLs in African Americans. PMID:32310939
prewas: data pre-processing for more informative bacterial GWAS. PMID:32310745
Loss of function mutations in CCDC32 cause a congenital syndrome characterized by craniofacial, cardiac and neurodevelopmental anomalies. PMID:32307552
DolphinNext: a distributed data processing platform for high throughput genomics. PMID:32306927
Corded Ware cultural complexity uncovered using genomic and isotopic analysis from south-eastern Poland. PMID:32303690
The circadian clock shapes the Arabidopsis transcriptome by regulating alternative splicing and alternative polyadenylation. PMID:32303634
Arabidopsis retrotransposon virus-like particles and their regulation by epigenetically activated small RNA. PMID:32303559
Leveraging mouse chromatin data for heritability enrichment informs common disease architecture and reveals cortical layer contributions to schizophrenia. PMID:32303558
Novel Genus of Phages Infecting Streptococcus thermophilus: Genomic and Morphological Characterization. PMID:32303549
PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding. PMID:32302532
High Complexity and Degree of Genetic Variation in Brettanomyces bruxellensis Population. PMID:32302403
A Whole-Genome Scan for Association with Invasion Success in the Fruit Fly Drosophila suzukii Using Contrasts of Allele Frequencies Corrected for Population Structure. PMID:32302396
Gene Function Rather than Reproductive Mode Drives the Evolution of RNA Helicases in Sexual and Apomictic Boechera. PMID:32302391
Identification of a novel archaea virus, detected in hydrocarbon polluted Hungarian and Canadian samples. PMID:32302368
Draft Genome Assembly for the Tibetan Black Bear (Ursus thibetanus thibetanus). PMID:32300354
Full genome sequencing of archived wild type and vaccine rinderpest virus isolates prior to their destruction. PMID:32300201
Whole genome sequencing for mutation discovery in a single case of lysosomal storage disease (MPS type 1) in the dog. PMID:32300136
Complete Genome Sequence of Halomonas meridiana Strain Slthf1, Isolated from a Deep-Sea Thermal Vent. PMID:32299885
Combined QTL mapping and RNA-Seq profiling reveals candidate genes associated with cadmium tolerance in barley. PMID:32298285
Transcriptome-guided parsimonious flux analysis improves predictions with metabolic networks in complex environments. PMID:32298268
Comparative Metagenome-Assembled Genome Analysis of "Candidatus Lachnocurva vaginae", Formerly Known as Bacterial Vaginosis-Associated Bacterium-1 (BVAB1). PMID:32296647
JunB Controls Intestinal Effector Programs in Regulatory T Cells. PMID:32296416
Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia. PMID:32296054
Species Identification and Antibiotic Resistance Prediction by Analysis of Whole-Genome Sequence Data by Use of ARESdb: an Analysis of Isolates from the Unyvero Lower Respiratory Tract Infection Trial. PMID:32295890
20-Hydroxyecdysone Primes Innate Immune Responses That Limit Bacterial and Malarial Parasite Survival in Anopheles gambiae. PMID:32295874
Phylogenomic Insights into Diversity and Evolution of Nonpathogenic Xanthomonas Strains Associated with Citrus. PMID:32295869
Comparative Transcriptomics Reveals Distinct Gene Expressions of a Model Ciliated Protozoa Feeding on Bacteria-Free Medium, Digestible, and Digestion-Resistant Bacteria. PMID:32295093
A WIZ/Cohesin/CTCF Complex Anchors DNA Loops to Define Gene Expression and Cell Identity. PMID:32294452
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity. PMID:32294406
A framework for gene mapping in wheat demonstrated using the Yr7 yellow rust resistance gene. PMID:32294096
Characterization of the chromatin accessibility in an Alzheimer's disease (AD) mouse model. PMID:32293531
Wide crossing diversify mitogenomes of rice. PMID:32293284
Transcriptomic diversity in seedling roots of European flint maize in response to cold. PMID:32293268
Molecular effects of dADD1 misexpression in chromatin organization and transcription. PMID:32293240
Identification of male heterogametic sex-determining regions on the Atlantic herring Clupea harengus genome. PMID:32293027
A negative storage model for precise but compact storage of genetic variation data. PMID:32293013
A Comparison of Co-expression Networks in Silk Gland Reveals the Causes of Silk Yield Increase During Silkworm Domestication. PMID:32292415
Genome-Wide Association Study and Fine Mapping Reveals Candidate Genes for Birth Weight of Yorkshire and Landrace Pigs. PMID:32292414
A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli. PMID:32291345
Transcriptional Patterning of the Ventricular Cardiac Conduction System. PMID:32290757
First Whole Genome Sequence of Anaplasma platys, an Obligate Intracellular Rickettsial Pathogen of Dogs. PMID:32290349
Epigenetic Requirements for Triggering Heterochromatinization and Piwi-Interacting RNA Production from Transgenes in the Drosophila Germline. PMID:32290057
The Aphid X Chromosome Is a Dangerous Place for Functionally Important Genes: Diverse Evolution of Hemipteran Genomes Based on Chromosome-Level Assemblies. PMID:32289166
Persistence of Brucella abortus lineages revealed by genomic characterization and phylodynamic analysis. PMID:32287327
The plant mobile domain proteins MAIN and MAIL1 interact with the phosphatase PP7L to regulate gene expression and silence transposable elements in Arabidopsis thaliana. PMID:32287271
Simultaneous measurement of biochemical phenotypes and gene expression in single cells. PMID:32286626
Characterization of viruses in a tapeworm: phylogenetic position, vertical transmission, and transmission to the parasitized host. PMID:32286546
An epigenetic map of malaria parasite development from host to vector. PMID:32286373
CdbA is a DNA-binding protein and c-di-GMP receptor important for nucleoid organization and segregation in Myxococcus xanthus. PMID:32286293
Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos. PMID:32286279
Transposable elements contribute to cell and species-specific chromatin looping and gene regulation in mammalian genomes. PMID:32286261
RLP/K enrichment sequencing; a novel method to identify receptor-like protein (RLP) and receptor-like kinase (RLK) genes. PMID:32285454
Sci-fate characterizes the dynamics of gene expression in single cells. PMID:32284584
Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis. PMID:32284543
Mapping of Adaptive Traits Enabled by a High-Density Linkage Map for Lake Trout. PMID:32284313
Expansion and Conservation of Biosynthetic Gene Clusters in Pathogenic Pyrenophora spp. PMID:32283749
Application of Adaptive Evolution to Improve the Stability of Bacteriophages during Storage. PMID:32283683
Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3' processing and transcription termination that functions via its effects on CTD phosphatase Ssu72. PMID:32282918
Conserved nuclear hormone receptors controlling a novel plastic trait target fast-evolving genes expressed in a single cell. PMID:32282814
Division of Labor between PCNA Loaders in DNA Replication and Sister Chromatid Cohesion Establishment. PMID:32277910
First Genome Sequence of the Gunnison's Prairie Dog (Cynomys gunnisoni), a Keystone Species and Player in the Transmission of Sylvatic Plague. PMID:32277812
Portable nanopore analytics: are we there yet? PMID:32277811
Species specific gene expression dynamics during harmful algal blooms. PMID:32277155
Tumour grade significantly correlates with total dysfunction of tumour tissue-infiltrating lymphocytes in renal cell carcinoma. PMID:32277125
Development of IFN-Stimulated Gene Expression from Embryogenesis through Adulthood, with and without Constitutive MDA5 Pathway Activation. PMID:32277054
Genome-Wide Changes in Genetic Diversity in a Population of Myotis lucifugus Affected by White-Nose Syndrome. PMID:32276959
Assembly and Analysis of the Complete Mitochondrial Genome of Capsella bursa-pastoris. PMID:32276324
Whole-Genome Promoter Profiling of Plasma DNA Exhibits Diagnostic Value for Placenta-Origin Pregnancy Complications. PMID:32274292
Ligneous Periodontitis in a Patient with Type 1 Plasminogen Deficiency: A Case Report and Review of the Literature. PMID:32274221
Transposable elements in individual genotypes of Drosophila simulans. PMID:32273997
Genomic Signatures of Selection Associated With Litter Size Trait in Jining Gray Goat. PMID:32273886
Computing Skin Cutaneous Melanoma Outcome From the HLA-Alleles and Clinical Characteristics. PMID:32273881
Comprehensive Transcriptome Analysis Reveals Insights into Phylogeny and Positively Selected Genes of Sillago Species. PMID:32272562
Molecular epidemiology of Salmonella Infantis in Europe: insights into the success of the bacterial host and its parasitic pESI-like megaplasmid. PMID:32271142
Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants. PMID:32269765
DNA punch cards for storing data on native DNA sequences via enzymatic nicking. PMID:32269230
Diversity of Secondary Metabolism in Aspergillus nidulans Clinical Isolates. PMID:32269157
TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4+ T Cells to Treg. PMID:32268093
Innate Immunity in the C. elegans Intestine Is Programmed by a Neuronal Regulator of AWC Olfactory Neuron Development. PMID:32268082
H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles. PMID:32266374
Impact of ex vivo Sample Handling on DNA Methylation Profiles in Human Cord Blood and Neonatal Dried Blood Spots. PMID:32265984
Comparison of SNP Calling Pipelines and NGS Platforms to Predict the Genomic Regions Harboring Candidate Genes for Nodulation in Cultivated Peanut. PMID:32265983
A Major QTL Located in Chromosome 8 of Cucurbita moschata Is Responsible for Resistance to Tomato Leaf Curl New Delhi Virus. PMID:32265946
A Novel pH-Regulated, Unusual 603 bp Overlapping Protein Coding Gene pop Is Encoded Antisense to ompA in Escherichia coli O157:H7 (EHEC). PMID:32265854
SMRT sequencing of the Oryza rufipogon genome reveals the genomic basis of rice adaptation. PMID:32265482
Adaptive Evolution of Geobacter sulfurreducens in Coculture with Pseudomonas aeruginosa. PMID:32265334
Tracking the Dairy Microbiota from Farm Bulk Tank to Skimmed Milk Powder. PMID:32265313
AthCNV: A Map of DNA Copy Number Variations in the Arabidopsis Genome. PMID:32265262
Using multiple reference genomes to identify and resolve annotation inconsistencies. PMID:32264824
Cohesin Causes Replicative DNA Damage by Trapping DNA Topological Stress. PMID:32259483
Genetic architecture of a key reproductive isolation trait differs between sympatric and non-sympatric sister species of Lake Victoria cichlids. PMID:32259470
Probabilistic model based on circular statistics for quantifying coverage depth dynamics originating from DNA replication. PMID:32257635
The chromosome-scale assembly of the willow genome provides insight into Salicaceae genome evolution. PMID:32257231
Genome-Wide Characterization of Alternative Splicing Events and Their Responses to Cold Stress in Tilapia. PMID:32256528
Performance of Mapping Approaches for Whole-Genome Bisulfite Sequencing Data in Crop Plants. PMID:32256504
Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy. PMID:32256442
Robinow Syndrome and Brachydactyly: An Interplay of High-Throughput Sequencing and Deep Phenotyping in a Kindred. PMID:32256301
Characterization of DNA methylation variations during fruit development and ripening of Vitis vinifera (cv. 'Fujiminori'). PMID:32255927
Novel frameshift mutations of ANKUB1, GLI3, and TAS2R3 associated with polysyndactyly in a Chinese family. PMID:32253825
Phase I Trial of Trametinib with Neoadjuvant Chemoradiation in Patients with Locally Advanced Rectal Cancer. PMID:32253228
Small and mighty: adaptation of superphylum Patescibacteria to groundwater environment drives their genome simplicity. PMID:32252814
Impact of phages on soil bacterial communities and nitrogen availability under different assembly scenarios. PMID:32252805
Complete genome sequence and annotation of the laboratory reference strain Shigella flexneri serotype 5a M90T and genome-wide transcriptional start site determination. PMID:32252626
Comparison of Read Mapping and Variant Calling Tools for the Analysis of Plant NGS Data. PMID:32252268
Large scale screening for benzimidazole resistance mutations in Nematodirus battus, using both pyrosequence genotyping and deep amplicon sequencing, indicates the early emergence of resistance on UK sheep farms. PMID:32251964
Inference of past demography, dormancy and self-fertilization rates from whole genome sequence data. PMID:32251472
Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ. PMID:32251394
Systematic alteration of ATAC-seq for profiling open chromatin in cryopreserved nuclei preparations from livestock tissues. PMID:32251359
Draft genomes of two Atlantic bay scallop subspecies Argopecten irradians irradians and A. i. concentricus. PMID:32251283
The honeybee (Apis mellifera) developmental state shapes the genetic composition of the deformed wing virus-A quasispecies during serial transmission. PMID:32249797
Accuracy of whole-genome sequence imputation using hybrid peeling in large pedigreed livestock populations. PMID:32248811
Characterizing pancreatic β-cell heterogeneity in the streptozotocin model by single-cell transcriptomic analysis. PMID:32247924
Genomic Analysis of Circulating Tumor Cells at the Single-Cell Level. PMID:32247862
Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS. PMID:32246942
High-density genetic variation maps reveal the correlation between asymmetric interspecific introgressions and improvement of agronomic traits in Upland and Pima cotton varieties developed in Xinjiang, China. PMID:32246786
Challenges and opportunities for strain verification by whole-genome sequencing. PMID:32245992
The Litsea genome and the evolution of the laurel family. PMID:32245969
A novel virtual barcode strategy for accurate panel-wide variant calling in circulating tumor DNA. PMID:32245364
Quantitative Trait Loci (QTLs) Associated with Microspore Culture in Raphanus sativus L. (Radish). PMID:32245207
Bulked Segregant Analysis Coupled with Whole-Genome Sequencing (BSA-Seq) Mapping Identifies a Novel pi21 Haplotype Conferring Basal Resistance to Rice Blast Disease. PMID:32245192
Cytoplasm Types Affect DNA Methylation among Different Cytoplasmic Male Sterility Lines and Their Maintainer Line in Soybean (Glycine max L.). PMID:32245080
Dissecting the Genetic Architecture of Aphanomyces Root Rot Resistance in Lentil by QTL Mapping and Genome-Wide Association Study. PMID:32244875
Dynamic Expression of Long Non-Coding RNAs Throughout Parasite Sexual and Neural Maturation in Schistosoma japonicum. PMID:32244675
Insights into the Synthesis, Secretion and Curing of Barnacle Cyprid Adhesive via Transcriptomic and Proteomic Analyses of the Cement Gland. PMID:32244485
Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection. PMID:32244344
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer. PMID:32243837
Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle. PMID:32242610
Genome resequencing reveals demographic history and genetic architecture of seed salinity tolerance in Populus euphratica. PMID:32242238
H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells. PMID:32242051
Complete Chromosomal Sequences of Two Borrelia miyamotoi Samples Obtained from Ixodes ricinus Eggs in Czechia. PMID:32241866
Two Synthetic 18-Way Outcrossed Populations of Diploid Budding Yeast with Utility for Complex Trait Dissection. PMID:32241804
Structure and function of the Arctic and Antarctic marine microbiota as revealed by metagenomics. PMID:32241287
ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection. PMID:32241270
Cell-type diversity and regionalized gene expression in the planarian intestine. PMID:32240093
Resolving mechanisms of immune-mediated disease in primary CD4 T cells. PMID:32239644
Genome-Wide Analysis of MicroRNA-related Single Nucleotide Polymorphisms (SNPs) in Mouse Genome. PMID:32238847
Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response. PMID:32238587
Molecular Drivers of Lymphocyte Organization in Vertebrate Mucosal Surfaces: Revisiting the TNF Superfamily Hypothesis. PMID:32238457
Analysis of the biodegradative and adaptive potential of the novel polychlorinated biphenyl degrader Rhodococcus sp. WAY2 revealed by its complete genome sequence. PMID:32238227
Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation. PMID:32238181
Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C. PMID:32236524
Multi-omics Visualization Platform: An extensible Galaxy plug-in for multi-omics data visualization and exploration. PMID:32236523
Genome and Transcriptome Sequencing of casper and roy Zebrafish Mutants Provides Novel Genetic Clues for Iridophore Loss. PMID:32235607
Whole-genome sequencing resolves a polyclonal outbreak by extended-spectrum beta-lactam and carbapenem-resistant Klebsiella pneumoniae in a Portuguese tertiary-care hospital. PMID:32234124
Bayesian reconstruction of Mycobacterium tuberculosis transmission networks in a high incidence area over two decades in Malawi reveals associated risk factors and genomic variants. PMID:32234123
Thousands of missing variants in the UK Biobank are recoverable by genome realignment. PMID:32232836
Accumulation of Deleterious Mutations in Landlocked Threespine Stickleback Populations. PMID:32232440
Detection of Circulating Tumor DNA in Patients With Uterine Leiomyomas. PMID:32232185
A Systematic Bioinformatics Workflow With Meta-Analytics Identified Potential Pathogenic Factors of Alzheimer's Disease. PMID:32231518
The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization. PMID:32231327
Stepwise selection on homeologous PRR genes controlling flowering and maturity during soybean domestication. PMID:32231277
Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression. PMID:32231273
Genetic and genomic analysis for cocoon yield traits in silkworm. PMID:32231221
A Whole Genome Re-Sequencing Based GWA Analysis Reveals Candidate Genes Associated with Ivermectin Resistance in Haemonchus contortus. PMID:32231078
A Sample-to-Report Solution for Taxonomic Identification of Cultured Bacteria in the Clinical Setting Based on Nanopore Sequencing. PMID:32229603
iMarmot: an integrative platform for comparative and functional genomics of marmots. PMID:32228437
Whole genome resequencing reveals an association of ABCC4 variants with preaxial polydactyly in pigs. PMID:32228435
Characterising the mechanisms underlying genetic resistance to amoebic gill disease in Atlantic salmon using RNA sequencing. PMID:32228433
Comparative analysis of genome-wide DNA methylation in Neurospora. PMID:32228351
An Annotated Chromosome-Level Reference Genome of the Red-Eared Slider Turtle (Trachemys scripta elegans). PMID:32227195
Transcriptome changes during the initiation and progression of Duchenne muscular dystrophy in Caenorhabditis elegans. PMID:32227114
PAIVS: prediction of avian influenza virus subtype. PMID:32224838
Validity of patient-derived xenograft mouse models for lung cancer based on exome sequencing data. PMID:32224836
Analysis of mitochondrial m1A/G RNA modification reveals links to nuclear genetic variants and associated disease processes. PMID:32221480
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking. PMID:32221288
Whole Genome Sequences of 23 Species from the Drosophila montium Species Group (Diptera: Drosophilidae): A Resource for Testing Evolutionary Hypotheses. PMID:32220952
Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing. PMID:32220304
Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation. PMID:32220301
Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro-myelinating genes. PMID:32219848
Divergence-Based Introgression Polarization. PMID:32219392
Homoeologous gene expression and co-expression network analyses and evolutionary inference in allopolyploids. PMID:32219306
Exploring the Consistency of the Quality Scores with Machine Learning for Next-Generation Sequencing Experiments. PMID:32219145
Alternative splicing and thermosensitive expression of Dmrt1 during urogenital development in the painted turtle, Chrysemys picta. PMID:32219017
Swimming exercise enhances brain plasticity in fish. PMID:32218982
Milk microbial composition of Brazilian dairy cows entering the dry period and genomic comparison between Staphylococcus aureus strains susceptible to the bacteriophage vB_SauM-UFV_DC4. PMID:32218514
Transcription polymerase-catalyzed emergence of novel RNA replicons. PMID:32217750
Comparison of NGS panel and Sanger sequencing for genotyping CAG repeats in the AR gene. PMID:32216057
Elevating seed oil content in a polyploid crop by induced mutations in SEED FATTY ACID REDUCER genes. PMID:32216029
Genomic variations in EBNA3C of EBV associate with posttransplant lymphoproliferative disorder. PMID:32213705
Two Lineages of KLRA with Contrasting Transcription Patterns Have Been Conserved at a Single Locus during Ruminant Speciation. PMID:32213565
Comparative Transcriptomic Analyses of Developing Melanocortin Neurons Reveal New Regulators for the Anorexigenic Neuron Identity. PMID:32213554
Quantification, Dynamic Visualization, and Validation of Bias in ATAC-Seq Data with ataqv. PMID:32213349
Diverse genetic mechanisms underlie worldwide convergent rice feralization. PMID:32213201
Myriocin-induced adaptive laboratory evolution of an industrial strain of Saccharomyces cerevisiae reveals its potential to remodel lipid composition and heat tolerance. PMID:32212314
The Quaternary evolutionary history of Bristol rock cress (Arabis scabra, Brassicaceae), a Mediterranean element with an outpost in the north-western Atlantic region. PMID:32211750
Detection of H3N8 influenza A virus with multiple mammalian-adaptive mutations in a rescued Grey seal (Halichoerus grypus) pup. PMID:32211197
An African origin for Mycobacterium bovis. PMID:32211193
MultiplexSSR: A pipeline for developing multiplex SSR-PCR assays from resequencing data. PMID:32211176
Restoration-mediated secondary contact leads to introgression of alewife ecotypes separated by a colonial-era dam. PMID:32211058
No Evidence of Persistence or Inheritance of Mitochondrial DNA Copy Number in Holocaust Survivors and Their Descendants. PMID:32211017
Rhizosphere assisted biodegradation of benzo(a)pyrene by cadmium resistant plant-probiotic Serratia marcescens S2I7, and its genomic traits. PMID:32210346
QTL-seq for identification of loci associated with resistance to Phytophthora crown rot in squash. PMID:32210312
Landscape of Mitochondria Genome and Clinical Outcomes in Stage 1 Lung Adenocarcinoma. PMID:32210009
Tailoring a Global Iron Regulon to a Uropathogen. PMID:32209682
Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress. PMID:32209474
Global genome diversity of the Leishmania donovani complex. PMID:32209228
Can we use it? On the utility of de novo and reference-based assembly of Nanopore data for plant plastome sequencing. PMID:32208422
Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence. PMID:32208170
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome. PMID:32207811
A molecular network regulating the proinflammatory phenotype of human memory T lymphocytes. PMID:32205878
Arabidopsis DNA Replication Initiates in Intergenic, AT-Rich Open Chromatin. PMID:32205451
Abnormal expression of GABAA receptor subunits and hypomotility upon loss of gabra1 in zebrafish. PMID:32205311
Evolutionary genetics of canine respiratory coronavirus and recent introduction into Swedish dogs. PMID:32205264
Multi-omics Analysis of Primary Cell Culture Models Reveals Genetic and Epigenetic Basis of Intratumoral Phenotypic Diversity. PMID:32205176
Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma. PMID:32203465
Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes. PMID:32203388
The complex genetic architecture of male mate choice evolution between Drosophila species. PMID:32203250
Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary. PMID:32203090
Spatially regulated editing of genetic information within a neuron. PMID:32201888
Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1. PMID:32200634
The genomic landscape of 8-oxodG reveals enrichment at specific inherently fragile promoters. PMID:32198884
A putative AGAMOUS ortholog is a candidate for the gene determining ease of dehulling in Tartary buckwheat (Fagopyrum tataricum). PMID:32198546
Dissecting the role of PfAP2-G in malaria gametocytogenesis. PMID:32198457
Benchmarking the MinION: Evaluating long reads for microbial profiling. PMID:32198413
OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. PMID:32198407
Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes. PMID:32198348
Identification and Characterization of the First Virulent Phages, Including a Novel Jumbo Virus, Infecting Ochrobactrum spp. PMID:32197547
Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak. PMID:32197085
Rampant Misexpression in a Mimulus (Monkeyflower) Introgression Line Caused by Hybrid Sterility, Not Regulatory Divergence. PMID:32196085
Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid. PMID:32196081
Quaternary climate changes as speciation drivers in the Amazon floodplains. PMID:32195336
Multiple Small RNAs Interact to Co-regulate Ethanol Tolerance in Zymomonas mobilis. PMID:32195236
B Cells as Prognostic Biomarker After Surgery for Colorectal Liver Metastases. PMID:32195184
FHIR Genomics: enabling standardization for precision medicine use cases. PMID:32194985
Demographic Inference of Divergence and Gene Exchange Between Castanopsis fabri and Castanopsis lamontii. PMID:32194597
Opossum Cathelicidins Exhibit Antimicrobial Activity Against a Broad Spectrum of Pathogens Including West Nile Virus. PMID:32194564
Genetic landscape of autism spectrum disorder in Vietnamese children. PMID:32193494
Co-abundance analysis reveals hidden players associated with high methane yield phenotype in sheep rumen microbiome. PMID:32193482
Cis-regulatory analysis of Onecut1 expression in fate-restricted retinal progenitor cells. PMID:32192535
VALOR2: characterization of large-scale structural variants using linked-reads. PMID:32192518
Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension. PMID:32192357
Foreign DNA detection by high-throughput sequencing to regulate genome-edited agricultural products. PMID:32188926
Exome sequencing identifies novel mutation signatures of UV radiation and trichostatin A in primary human keratinocytes. PMID:32188867
Stable species boundaries despite ten million years of hybridization in tropical eels. PMID:32188850
An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2. PMID:32188783
Global Regulation of the Histone Mark H3K36me2 Underlies Epithelial Plasticity and Metastatic Progression. PMID:32188706
Accurate and complete genomes from metagenomes. PMID:32188701
A Turkey-origin H9N2 Avian Influenza Virus Shows Low Pathogenicity but Different Within-Host Diversity in Experimentally Infected Turkeys, Quail and Ducks. PMID:32188100
Epigenetic engineering of yeast reveals dynamic molecular adaptation to methylation stress and genetic modulators of specific DNMT3 family members. PMID:32187373
Transcriptional regulation of genes bearing intronic heterochromatin in the rice genome. PMID:32187179
Cooperation and Cheating through a Secreted Aminopeptidase in the Pseudomonas aeruginosa RpoS Response. PMID:32184248
Dynamics of genetic variation in transcription factors and its implications for the evolution of regulatory networks in Bacteria. PMID:32182360
YBEY is an essential biogenesis factor for mitochondrial ribosomes. PMID:32182356
Kin28 depletion increases association of TFIID subunits Taf1 and Taf4 with promoters in Saccharomyces cerevisiae. PMID:32182349
Matching Reads to Many Genomes with the r-Index. PMID:32181686
Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells. PMID:32181346
Whole Genome Scan and Selection Signatures for Climate Adaption in Yanbian Cattle. PMID:32180793
Mendelian Randomization Identifies CpG Methylation Sites With Mediation Effects for Genetic Influences on BMD in Peripheral Blood Monocytes. PMID:32180791
Parallel evolution of dominant pistil-side self-incompatibility suppressors in Arabidopsis. PMID:32179752
Gut microbiome diversity detected by high-coverage 16S and shotgun sequencing of paired stool and colon sample. PMID:32179734
Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions. PMID:32179580
A deletion in Eml1 leads to bilateral subcortical heterotopia in the tish rat. PMID:32179177
Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing. PMID:32176719
The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis. PMID:32176689
Origin, genomic diversity and microevolution of the Clostridium difficile B1/NAP1/RT027/ST01 strain in Costa Rica, Chile, Honduras and Mexico. PMID:32176604
Complex Evolutionary History of the Y Chromosome in Flies of the Drosophila obscura Species Group. PMID:32176296
Fine-mapping and transcriptome analysis of a candidate gene controlling plant height in Brassica napus L. PMID:32175009
Complete Genome Insights into Lactococcus petauri CF11 Isolated from a Healthy Human Gut Using Second- and Third-Generation Sequencing. PMID:32174973
STRsearch: a new pipeline for targeted profiling of short tandem repeats in massively parallel sequencing data. PMID:32172688
Ultraplexing: increasing the efficiency of long-read sequencing for hybrid assembly with k-mer-based multiplexing. PMID:32171299
Tracy: basecalling, alignment, assembly and deconvolution of sanger chromatogram trace files. PMID:32171249
Production of multiple bacteriocins, including the novel bacteriocin gassericin M, by Lactobacillus gasseri LM19, a strain isolated from human milk. PMID:32170384
Anthoceros genomes illuminate the origin of land plants and the unique biology of hornworts. PMID:32170292
Integrated multi-omics framework of the plant response to jasmonic acid. PMID:32170290
A megaplasmid family driving dissemination of multidrug resistance in Pseudomonas. PMID:32170080
YTHDF2 destabilizes m6A-modified neural-specific RNAs to restrain differentiation in induced pluripotent stem cells. PMID:32169943
Temperature and Nutrient Levels Correspond with Lineage-Specific Microdiversification in the Ubiquitous and Abundant Freshwater Genus Limnohabitans. PMID:32169939
Association Between Lifelong Premature Ejaculation and Polymorphism of Tryptophan Hydroxylase 2 Gene in the Han Population. PMID:32169437
NR2F2 Orphan Nuclear Receptor is Involved in Estrogen Receptor Alpha-Mediated Transcriptional Regulation in Luminal A Breast Cancer Cells. PMID:32168782
Comparative genomic analysis of inbred rat strains reveals the existence of ancestral polymorphisms. PMID:32166433
Mild drought in the vegetative stage induces phenotypic, gene expression, and DNA methylation plasticity in Arabidopsis but no transgenerational effects. PMID:32166321
Ancient mtDNA from the extinct Indian cheetah supports unexpectedly deep divergence from African cheetahs. PMID:32165662
Impact of the gut microbiota on the m6A epitranscriptome of mouse cecum and liver. PMID:32165618
Draft genomes of female and male turbot Scophthalmus maximus. PMID:32165614
Pathogen Genetic Control of Transcriptome Variation in the Arabidopsis thaliana - Botrytis cinerea Pathosystem. PMID:32165442
Targeted Exome Sequencing Provided Comprehensive Genetic Diagnosis of Congenital Anomalies of the Kidney and Urinary Tract. PMID:32164334
Mapping of the chicken cleft primary palate mutation on chromosome 11 and sequencing of the 4.9 Mb linked region. PMID:32162363
Fine-Scale Population Genetic Structure and Parapatric Cryptic Species of Kuruma Shrimp (Marsupenaeus japonicus), Along the Northwestern Pacific Coast of China. PMID:32161618
Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells. PMID:32161592
Pseudohyphal Growth of the Emerging Pathogen Candida auris Is Triggered by Genotoxic Stress through the S Phase Checkpoint. PMID:32161147
The Arabidopsis SAFEGUARD1 suppresses singlet oxygen-induced stress responses by protecting grana margins. PMID:32161131
Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors. PMID:32161105
An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement. PMID:32160709
Pan-Cancer Analysis Reveals the Diverse Landscape of Novel Sense and Antisense Fusion Transcripts. PMID:32160708
The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1. PMID:32160533
Fibroblast-specific genome-scale modelling predicts an imbalance in amino acid metabolism in Refsum disease. PMID:32160399
Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin. PMID:32157249
Humans Are Selectively Exposed to Pneumocystis jirovecii. PMID:32156824
Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress. PMID:32156729
Genomic loci susceptible to systematic sequencing bias in clinical whole genomes. PMID:32156711
Sex-specific impact of inbreeding on pathogen load in the striped dolphin. PMID:32156218
Population Genomic Analysis of Two Endemic Schizothoracins Reveals Their Genetic Differences and Underlying Selection Associated with Altitude and Temperature. PMID:32156058
Mapping-by-Sequencing via MutMap Identifies a Mutation in ZmCLE7 Underlying Fasciation in a Newly Developed EMS Mutant Population in an Elite Tropical Maize Inbred. PMID:32155750
Two MYB Proteins in a Self-Organizing Activator-Inhibitor System Produce Spotted Pigmentation Patterns. PMID:32155414
HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer. PMID:32154941
Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells. PMID:32154791
Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages. PMID:32154616
SECNVs: A Simulator of Copy Number Variants and Whole-Exome Sequences From Reference Genomes. PMID:32153642
A Guide to Carrying Out a Phylogenomic Target Sequence Capture Project. PMID:32153629
Full Transcriptomic Response of Pseudomonas aeruginosa to an Inulin-Derived Fructooligosaccharide. PMID:32153524
Combining short and long read sequencing to characterize antimicrobial resistance genes on plasmids applied to an unauthorized genetically modified Bacillus. PMID:32152350
A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons. PMID:32152282
A progesterone biosensor derived from microbial screening. PMID:32152281
The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity. PMID:32152212
Translational efficiency across healthy and tumor tissues is proliferation-related. PMID:32149479
Comprehensive phenotyping and transcriptome profiling to study nanotoxicity in C. elegans. PMID:32149031
A-to-I RNA Editing Uncovers Hidden Signals of Adaptive Genome Evolution in Animals. PMID:32145015
Transposon age and non-CG methylation. PMID:32144266
Reciprocal monoallelic expression of ASAR lncRNA genes controls replication timing of human chromosome 6. PMID:32144193
Rif1 Functions in a Tissue-Specific Manner To Control Replication Timing Through Its PP1-Binding Motif. PMID:32144132
Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex. PMID:32143680
Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain. PMID:32143622
CNV Radar: an improved method for somatic copy number alteration characterization in oncology. PMID:32143562
MiR&moRe2: A Bioinformatics Tool to Characterize microRNAs and microRNA-Offset RNAs from Small RNA-Seq Data. PMID:32143373
Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids. PMID:32142678
Regulation of the RNAPII Pool Is Integral to the DNA Damage Response. PMID:32142654
Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua. PMID:32142631
RNA-guided retargeting of Sleeping Beauty transposition in human cells. PMID:32142408
Mycoparasitism illuminated by genome and transcriptome sequencing of Coniothyrium minitans, an important biocontrol fungus of the plant pathogen Sclerotinia sclerotiorum. PMID:32141811
Successful field performance in warm and dry environments of soybean expressing the sunflower transcription factor HB4. PMID:32140724
Transcriptomic data of Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S treated with novobiocin. PMID:32140513
Discovery of the Genomic Region and Candidate Genes of the Scarlet Red Flesh Color (Yscr ) Locus in Watermelon (Citrullus Lanatus L.). PMID:32140168
53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice. PMID:32139898
Genome-wide transcriptome and physiological analyses provide new insights into peanut drought response mechanisms. PMID:32139708
Draft Genome Sequence of an Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolate, 3485_MTB, from Nur-Sultan, Kazakhstan. PMID:32139580
Complete Genome Sequence of Streptococcus ratti JH145. PMID:32139573
Evaluation of Seven Different RNA-Seq Alignment Tools Based on Experimental Data from the Model Plant Arabidopsis thaliana. PMID:32138290
Pathogen to commensal? Longitudinal within-host population dynamics, evolution, and adaptation during a chronic >16-year Burkholderia pseudomallei infection. PMID:32134991
ASA3P: An automatic and scalable pipeline for the assembly, annotation and higher-level analysis of closely related bacterial isolates. PMID:32134915
Genome Architecture Facilitates Phenotypic Plasticity in the Honeybee (Apis mellifera). PMID:32134461
Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis. PMID:32134383
Enhancer occlusion transcripts regulate the activity of human enhancer domains via transcriptional interference: a computational perspective. PMID:32133533
Treatment of an aggressive orthotopic murine glioblastoma model with combination checkpoint blockade and a multivalent neoantigen vaccine. PMID:32133512
KRGDB: the large-scale variant database of 1722 Koreans based on whole genome sequencing. PMID:32133509
Genomic evidence for two phylogenetic species and long-term population bottlenecks in red pandas. PMID:32133395
PromA Plasmids Are Instrumental in the Dissemination of Linuron Catabolic Genes Between Different Genera. PMID:32132980
Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy. PMID:32132540
Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9. PMID:32132530
Bottleneck Size-Dependent Changes in the Genetic Diversity and Specific Growth Rate of a Rotavirus A Strain. PMID:32132235
Nanopore Sequencing Reveals Novel Targets for Detection and Surveillance of Human and Avian Influenza A Viruses. PMID:32132187
Mutagenesis of a Quintuple Mutant Impaired in Environmental Responses Reveals Roles for CHROMATIN REMODELING4 in the Arabidopsis Floral Transition. PMID:32132131
Alcohol Causes Lasting Differential Transcription in Drosophila Mushroom Body Neurons. PMID:32132098
Genome-wide analysis reveals molecular convergence underlying domestication in 7 bird and mammals. PMID:32131728
Insight into unique somitogenesis of yak (Bos grunniens) with one additional thoracic vertebra. PMID:32131721
Whole genome resequencing of the Iranian native dogs and wolves to unravel variome during dog domestication. PMID:32131720
Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development. PMID:32130906
Comparative and population genomics approaches reveal the basis of adaptation to deserts in a small rodent. PMID:32130752
Linezolid resistance in Enterococcus faecium and Enterococcus faecalis from hospitalized patients in Ireland: high prevalence of the MDR genes optrA and poxtA in isolates with diverse genetic backgrounds. PMID:32129849
Identification of rare variants in novel candidate genes in pulmonary atresia patients by next generation sequencing. PMID:32128068
Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance. PMID:32127614
Phylogenomics of Rhodocyclales and its distribution in wastewater treatment systems. PMID:32127605
Four European Salmonella Typhimurium datasets collected to develop WGS-based source attribution methods. PMID:32127544
The mTOR pathway is necessary for survival of mice with short telomeres. PMID:32127537
NanoVar: accurate characterization of patients' genomic structural variants using low-depth nanopore sequencing. PMID:32127024
Integrative analysis of the genomic and transcriptomic landscape of double-refractory multiple myeloma. PMID:32126144
IRF4 instructs effector Treg differentiation and immune suppression in human cancer. PMID:32125291
Parentage and relatedness reconstruction in Pinus sylvestris using genotyping-by-sequencing. PMID:32123330
The Gossypium longicalyx Genome as a Resource for Cotton Breeding and Evolution. PMID:32122962
Genetic diversity among cultivated beets (Beta vulgaris) assessed via population-based whole genome sequences. PMID:32122300
Identification of Two Novel Peanut Genotypes Resistant to Aflatoxin Production and Their SNP Markers Associated with Resistance. PMID:32121605
Genetic Identification and Transcriptome Analysis of Lintless and Fuzzless Traits in Gossypium arboreum L. PMID:32121400
Phylogeography and the Evolutionary History of Sunflower (Helianthus annuus L.): Wild Diversity and the Dynamics of Domestication. PMID:32121324
Alternatively Constructed Estrogen Receptor Alpha-Driven Super-Enhancers Result in Similar Gene Expression in Breast and Endometrial Cell Lines. PMID:32120995
Characterization of A Homozygous Deletion of Steroid Hormone Biosynthesis Genes in Horse Chromosome 29 as A Risk Factor for Disorders of Sex Development and Reproduction. PMID:32120906
The Segment Matters: Probable Reassortment of Tilapia Lake Virus (TiLV) Complicates Phylogenetic Analysis and Inference of Geographical Origin of New Isolate from Bangladesh. PMID:32120863
Trends in Helicobacter pylori resistance to clarithromycin: from phenotypic to genomic approaches. PMID:32118532
Genetic Variation Related to High Elevation Adaptation Revealed by Common Garden Experiments in Pinus yunnanensis. PMID:32117429
Alveolar Macrophage Chromatin Is Modified to Orchestrate Host Response to Mycobacterium bovis Infection. PMID:32117424
Suitability of Single-Nucleotide Polymorphism Arrays Versus Genotyping-By-Sequencing for Genebank Genomics in Wheat. PMID:32117381
Exploring Rain as Source of Biological Control Agents for Fire Blight on Apple. PMID:32117187
Enterococcus faecalis Adapts to Antimicrobial Conjugated Oligoelectrolytes by Lipid Rearrangement and Differential Expression of Membrane Stress Response Genes. PMID:32117172
A novel NGS library preparation method to characterize native termini of fragmented DNA. PMID:32112100
The genetics of situs inversus without primary ciliary dyskinesia. PMID:32111882
Chromosome-Level Assembly of the Caenorhabditis remanei Genome Reveals Conserved Patterns of Nematode Genome Organization. PMID:32111628
Bacteria from the Genus Arcobacter Are Abundant in Effluent from Wastewater Treatment Plants. PMID:32111585
Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors. PMID:32111235
Association between gene polymorphisms of voltage-dependent Ca2+ channels and hypertension in the Dai people of China: a case-control study. PMID:32111194
Effects of sample age on data quality from targeted sequencing of museum specimens: what are we capturing in time? PMID:32111157
Integrated Mobile Element Scanning (ME-Scan) method for identifying multiple types of polymorphic mobile element insertions. PMID:32110248
Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. PMID:32109204
Genomic divergence reveals unique populations among Indian Yaks. PMID:32108137
Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis. PMID:32107493
Genetic Profile and Functional Proteomics of Anal Squamous Cell Carcinoma: Proposal for a Molecular Classification. PMID:32107283
Accurate Sex Identification of Ancient Elephant and Other Animal Remains Using Low-Coverage DNA Shotgun Sequencing Data. PMID:32107273
Clinical Implications of Circulating Tumor DNA from Ascites and Serial Plasma in Ovarian Cancer. PMID:32106643
Streptococcus pneumoniae Nasopharyngeal Carriage among PCV-10-Vaccinated HIV-1-Infected Children with Maintained Serological Memory in Ethiopia. PMID:32106620
Molecular Mechanisms Underpinning Aggregation in Acidiphilium sp. C61 Isolated from Iron-Rich Pelagic Aggregates. PMID:32106516
Stress Reshapes the Physiological Response of Halophile Fungi to Salinity. PMID:32106416
Population structure and antimicrobial resistance patterns of Salmonella Typhi isolates in urban Dhaka, Bangladesh from 2004 to 2016. PMID:32106221
Quantitative comparison of within-sample heterogeneity scores for DNA methylation data. PMID:32103242
Two conserved epigenetic regulators prevent healthy ageing. PMID:32103178
High-Throughput CRISPR/Cas9 Mutagenesis Streamlines Trait Gene Identification in Maize. PMID:32102844
The Ligon lintless -2 Short Fiber Mutation Is Located within a Terminal Deletion of Chromosome 18 in Cotton. PMID:32102829
Allosteric inhibition of CRISPR-Cas9 by bacteriophage-derived peptides. PMID:32102684
Concordance of SNP- and allele-based typing workflows in the context of a large-scale international Salmonella Enteritidis outbreak investigation. PMID:32101514
Comparison of Shiga toxin-encoding bacteriophages in highly pathogenic strains of Shiga toxin-producing Escherichia coli O157:H7 in the UK. PMID:32100710
Detection of live attenuated influenza vaccine virus and evidence of reassortment in the U.S. swine population. PMID:32100644
Shared genetic susceptibilities for irritable bowel syndrome and depressive disorder in Chinese patients uncovered by pooled whole-exome sequencing. PMID:32099673
Whole genome sequencing of Herpes Simplex Virus 1 directly from human cerebrospinal fluid reveals selective constraints in neurotropic viruses. PMID:32099667
A Rare Glimpse into the Past of the Anthrax Pathogen Bacillus anthracis. PMID:32098212
Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity. PMID:32097448
Human RAP1 specifically protects telomeres of senescent cells from DNA damage. PMID:32096305
Genetic and evolution analysis of extrafloral nectary in cotton. PMID:32096298
Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery. PMID:32095820
Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes. PMID:32095818
Phylogenomic analysis of 589 metagenome-assembled genomes encompassing all major prokaryotic lineages from the gut of higher termites. PMID:32095380
The spread of steppe and Iranian-related ancestry in the islands of the western Mediterranean. PMID:32094539
Comparison of Mendeliome exome capture kits for use in clinical diagnostics. PMID:32094380
Deconvoluting Wavelengths Leading to Fluorescent Light Induced Inflammation and Cellular Stress in Zebrafish (Danio rerio). PMID:32094353
The sequence and de novo assembly of the wild yak genome. PMID:32094352
RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions. PMID:32094342
Integration, abundance, and transmission of mutations and transgenes in a series of CRISPR/Cas9 soybean lines. PMID:32093670
Adaptation to Photooxidative Stress: Common and Special Strategies of the Alphaproteobacteria Rhodobacter sphaeroides and Rhodobacter capsulatus. PMID:32093084
Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors. PMID:32092934
Testis transcriptome profiling identified genes involved in spermatogenic arrest of cattleyak. PMID:32092127
A spontaneous complex structural variant in rcan-1 increases exploratory behavior and laboratory fitness of Caenorhabditis elegans. PMID:32092052
Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer. PMID:32091413
Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Beijing Clades, Ukraine, 2015. PMID:32091369
Mycobacterium tuberculosis Beijing Lineage and Risk for Tuberculosis in Child Household Contacts, Peru. PMID:32091363
Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension. PMID:32090860
Whole-Genome Resequencing of Twenty Branchiostoma belcheri Individuals Provides a Brand-New Variant Dataset for Branchiostoma. PMID:32090082
An office building outbreak: the changing epidemiology of tuberculosis in Shenzhen, China. PMID:32089146
FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation. PMID:32086523
Identification of Suppressors of top-2 Embryonic Lethality in Caenorhabditis elegans. PMID:32086248
Can rumen bacteria communicate to each other? PMID:32085816
Deconvolution of RNA-Seq Analysis of Hyperbaric Oxygen-Treated Mice Lungs Reveals Mesenchymal Cell Subtype Changes. PMID:32085618
CRISPR/Cas9-Mediated Mutagenesis of RCO in Cardamine hirsuta. PMID:32085527
Mitochondrial DNA Repair in an Arabidopsis thaliana Uracil N-Glycosylase Mutant. PMID:32085412
Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated With Monogenic Variants, Identified by Whole-Exome Sequencing in 1000 Children at a Single Center. PMID:32084423
Functional Heterogeneity within the Developing Zebrafish Epicardium. PMID:32084358
Comparative genomic analysis of Proteus spp. isolated from tree shrews indicated unexpectedly high genetic diversity. PMID:32084183
Evolution of Ty1 copy number control in yeast by horizontal transfer and recombination. PMID:32084126
Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes. PMID:32084124
Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival. PMID:32083805
Can-Seq: a PCR and DNA sequencing strategy for identifying new alleles of known and candidate genes. PMID:32082406
Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches. PMID:32082376
A Resequencing-Based Ultradense Genetic Map of Hericium erinaceus for Anchoring Genome Sequences and Identifying Genetic Loci Associated With Monokaryon Growth. PMID:32082271
Current Affairs of Microbial Genome-Wide Association Studies: Approaches, Bottlenecks and Analytical Pitfalls. PMID:32082269
Local rewiring of genome-nuclear lamina interactions by transcription. PMID:32080885
Decimated little brown bats show potential for adaptive change. PMID:32080246
Chromosome-level assemblies of multiple Arabidopsis genomes reveal hotspots of rearrangements with altered evolutionary dynamics. PMID:32080174
The cryptic unstable transcripts are associated with developmentally regulated gene expression in blood-stage Plasmodium falciparum. PMID:32079470
Misregulation of ELK1, AP1, and E12 Transcription Factor Networks Is Associated with Melanoma Progression. PMID:32079144
Isolation of PCV3 from Perinatal and Reproductive Cases of PCV3-Associated Disease and In Vivo Characterization of PCV3 Replication in CD/CD Growing Pigs. PMID:32079070
Comparison of sequencing methods and data processing pipelines for whole genome sequencing and minority single nucleotide variant (mSNV) analysis during an influenza A/H5N8 outbreak. PMID:32078666
Transcriptome-based target-enrichment baits for stony corals (Cnidaria: Anthozoa: Scleractinia). PMID:32077619
A yeast-based complementation assay elucidates the functional impact of 200 missense variants in human PSAT1. PMID:32077105
Decoding a highly mixed Kazakh genome. PMID:32076829
Knockdown of GmVQ58 encoding a VQ motif-containing protein enhances soybean resistance to the common cutworm (Spodoptera litura Fabricius). PMID:32076725
RAPTURE (RAD capture) panel facilitates analyses characterizing sea lamprey reproductive ecology and movement dynamics. PMID:32076528
Functional Characterization of a Missense Variant of MLH1 Identified in Lynch Syndrome Pedigree. PMID:32076465
The R-Loop Atlas of Arabidopsis Development and Responses to Environmental Stimuli. PMID:32075864
Construction and characterization of a knock-down RNA interference line of OsNRPD1 in rice (Oryza sativa ssp japonica cv Nipponbare). PMID:32075556
Transposable elements have contributed human regulatory regions that are activated upon bacterial infection. PMID:32075553
Comparative Analysis of Structural Variations Due to Genome Shuffling of Bacillus Subtilis VS15 for Improved Cellulase Production. PMID:32075107
Genetic Dissection of Germinability under Low Temperature by Building a Resequencing Linkage Map in japonica Rice. PMID:32074988
A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia. PMID:32074275
Gene expression profile suggesting immunological dysregulation in two Brazilian Bloom's syndrome cases. PMID:32073752
Resequencing 93 accessions of coffee unveils independent and parallel selection during Coffea species divergence. PMID:32072392
Whole genomic sequencing and sex-dependent abundance estimation of Cardinium sp., a common and hyperabundant bacterial endosymbiont of the American house dust mite, Dermatophagoides farinae. PMID:32072355
Early detection of lysosomal diseases by screening of cases of idiopathic splenomegaly and/or thrombocytopenia with a next-generation sequencing gene panel. PMID:32071839
Unexpectedly high genetic diversity in a rare and endangered seabird in the Hawaiian Archipelago. PMID:32071808
Variant phasing and haplotypic expression from long-read sequencing in maize. PMID:32071408
RNA cargos in extracellular vesicles derived from blood serum in pancreas associated conditions. PMID:32071328
A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions. PMID:32071317
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. PMID:32071302
Plant Virus Genome Is Shaped by Specific Dinucleotide Restrictions That Influence Viral Infection. PMID:32071264
Dairy Products and Dairy-Processing Environments as a Reservoir of Antibiotic Resistance and Quorum-Quenching Determinants as Revealed through Functional Metagenomics. PMID:32071160
Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients. PMID:32071060
Genome-wide identification of the context-dependent sRNA expression in Mycobacterium tuberculosis. PMID:32070281
Thyroid Deficiency Before Birth Alters the Adipose Transcriptome to Promote Overgrowth of White Adipose Tissue and Impair Thermogenic Capacity. PMID:32070265
From astrocytoma to glioblastoma: a clonal evolution study. PMID:32069381
The persimmon genome reveals clues to the evolution of a lineage-specific sex determination system in plants. PMID:32069274
Novel de Novo Genome of Cynopterus brachyotis Reveals Evolutionarily Abrupt Shifts in Gene Family Composition across Fruit Bats. PMID:32068833
EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. PMID:32066955
Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese population. PMID:32066856
Targeted exome sequencing identifies five novel loci at genome-wide significance for modulating antidepressant response in patients with major depressive disorder. PMID:32066657
The pan-cancer landscape of prognostic germline variants in 10,582 patients. PMID:32066500
Identification of genome-wide single-nucleotide polymorphisms among geographically diverse radish accessions. PMID:32065621
Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver. PMID:32064334
Transcriptome analysis of rat dorsal hippocampal CA1 after an early life seizure induced by kainic acid. PMID:32062370
Evolutionary Analysis of the Bacillus subtilis Genome Reveals New Genes Involved in Sporulation. PMID:32061128
Double-stranded DNA virioplankton dynamics and reproductive strategies in the oligotrophic open ocean water column. PMID:32060418
A willow sex chromosome reveals convergent evolution of complex palindromic repeats. PMID:32059685
Epigenetic loss of heterozygosity of Apc and an inflammation-associated mutational signature detected in Lrig1+/--driven murine colonic adenomas. PMID:32059662
Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity. PMID:32057297
Evolutionary analysis of the most polymorphic gene family in falciparum malaria. PMID:32055709
Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe. PMID:32055708
Complicated paroxysmal kinesigenic dyskinesia associated with SACS mutations. PMID:32055599
Field cricket genome reveals the footprint of recent, abrupt adaptation in the wild. PMID:32055408
Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines. PMID:32055257
Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice. PMID:32054990
Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal. PMID:32054988
Sweet potato viromes in eight different geographical regions in Korea and two different cultivars. PMID:32054944
MicroRNAs regulate innate immunity against uropathogenic and commensal-like Escherichia coli infections in the surrogate insect model Galleria mellonella. PMID:32054914
Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation. PMID:32054864
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity. PMID:32054838
Excess of singleton loss-of-function variants in Parkinson's disease contributes to genetic risk. PMID:32054687
Assessment of a multiplex PCR and Nanopore-based method for dengue virus sequencing in Indonesia. PMID:32054488
Molecular bases for drought tolerance in common vetch: designing new molecular breeding tools. PMID:32054459
Spatiotemporal Differentiation of Alpine Butterfly Parnassius glacialis (Papilionidae: Parnassiinae) in China: Evidence from Mitochondrial DNA and Nuclear Single Nucleotide Polymorphisms. PMID:32053967
Context-Dependent Gene Regulation by Homeodomain Transcription Factor Complexes Revealed by Shape-Readout Deficient Proteins. PMID:32053778
A molecular barcode to inform the geographical origin and transmission dynamics of Plasmodium vivax malaria. PMID:32053607
GC bias affects genomic and metagenomic reconstructions, underrepresenting GC-poor organisms. PMID:32052832
DNA copy-number measurement of genome replication dynamics by high-throughput sequencing: the sort-seq, sync-seq and MFA-seq family. PMID:32051615
MAFG-driven astrocytes promote CNS inflammation. PMID:32051591
Loss of p53 drives neuron reprogramming in head and neck cancer. PMID:32051587
ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis. PMID:32051414
Variant antigen diversity in Trypanosoma vivax is not driven by recombination. PMID:32051413
Notch controls urothelial integrity in the mouse bladder. PMID:32051338
Assembly of hundreds of novel bacterial genomes from the chicken caecum. PMID:32051016
The wild species genome ancestry of domestic chickens. PMID:32050971
Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis. PMID:32050897
The signature of pharmaceutical sensitivity based on ctDNA mutation in eleven cancers. PMID:32050795
Metagenome SNP calling via read-colored de Bruijn graphs. PMID:32049324
Mammalian RNA Decay Pathways Are Highly Specialized and Widely Linked to Translation. PMID:32048998
Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning-enabled molecular diagnostics. PMID:32048461
Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome. PMID:32047912
Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks. PMID:32047271
A novel next generation sequencing approach to improve sarcoma diagnosis. PMID:32047232
QTL-Seq and Sequence Assembly Rapidly Mapped the Gene BrMYBL2.1 for the Purple Trait in Brassica rapa. PMID:32047197
Genome Dynamics of Vibrio cholerae Isolates Linked to Seasonal Outbreaks of Cholera in Dhaka, Bangladesh. PMID:32047137
ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells. PMID:32046982
A 19-isolate reference-quality global pangenome for the fungal wheat pathogen Zymoseptoria tritici. PMID:32046716
Compacta: a fast contig clustering tool for de novo assembled transcriptomes. PMID:32046653
Comparative population genomics reveals genetic divergence and selection in lotus, Nelumbo nucifera. PMID:32046648
Analysis of molecular mechanism for acceleration of polyembryony using gene functional annotation pipeline in Copidosoma floridanum. PMID:32046635
Combining genomics and epidemiology to track mumps virus transmission in the United States. PMID:32045407
LUMI-PCR: an Illumina platform ligation-mediated PCR protocol for integration site cloning, provides molecular quantitation of integration sites. PMID:32042315
Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma. PMID:32042196
Rapid inference of antibiotic resistance and susceptibility by genomic neighbour typing. PMID:32042129
QTL mapping of yield component traits on bin map generated from resequencing a RIL population of foxtail millet (Setaria italica). PMID:32041544
A genome-wide scan study identifies a single nucleotide substitution in the tyrosinase gene associated with white coat colour in a red deer (Cervus elaphus) population. PMID:32041521
Identification of RNA 3´ ends and termination sites in Haloferax volcanii. PMID:32041469
Molecular-Assisted Distinctness and Uniformity Testing Using SLAF-Sequencing Approach in Soybean. PMID:32041312
Whole genome sequencing unveils genetic heterogeneity in optic nerve hypoplasia. PMID:32040484
In silico prediction and expression profile analysis of small non-coding RNAs in Herbaspirillum seropedicae SmR1. PMID:32039705
High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia. PMID:32039702
SeqBreed: a python tool to evaluate genomic prediction in complex scenarios. PMID:32039696
Assaying Chromatin Accessibility Using ATAC-Seq in Invertebrate Chordate Embryos. PMID:32039199
Genetic Diversities and Differentially Selected Regions Between Shandong Indigenous Pig Breeds and Western Pig Breeds. PMID:32038711
Genomics Evolutionary History and Diagnostics of the Alternaria alternata Species Group Including Apple and Asian Pear Pathotypes. PMID:32038562
Cancer transcriptomic profiling from rapidly enriched circulating tumor cells. PMID:32037533
Characterization of basal and estrogen-regulated antisense transcription in breast cancer cells: Role in regulating sense transcription. PMID:32035111
Multiplexed clonality verification of cell lines for protein biologic production. PMID:32034880
Post-mortem Plasma Cell-Free DNA Sequencing: Proof-of-Concept Study for the "Liquid Autopsy". PMID:32034265
An efficient RNA-seq-based segregation analysis identifies the sex chromosomes of Cannabis sativa. PMID:32033943
Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes. PMID:32033836
Combinatorial Discriminant Analysis Applied to RNAseq Data Reveals a Set of 10 Transcripts as Signatures of Exposure of Cattle to Mycobacterium avium subsp. paratuberculosis. PMID:32033399
Chromosome and Genome Divergence between the Cryptic Eurasian Malaria Vector-Species Anopheles messeae and Anopheles daciae. PMID:32033356
Integrated Genome-Wide Analysis of an Isogenic Pair of Pseudomonas aeruginosa Clinical Isolates with Differential Antimicrobial Resistance to Ceftolozane/Tazobactam, Ceftazidime/Avibactam, and Piperacillin/Tazobactam. PMID:32033143
Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons. PMID:32032531
Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18. PMID:32031521
Functional Architecture of Deleterious Genetic Variants in the Genome of a Wrangel Island Mammoth. PMID:32031213
Genomic signatures and candidate genes of lint yield and fibre quality improvement in Upland cotton in Xinjiang. PMID:32030869
Germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors. PMID:32029870
Integrative genomic study of Chinese clear cell renal cell carcinoma reveals features associated with thrombus. PMID:32029730
Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia. PMID:32029721
Five Complete Genome Sequences Spanning the Dutch Streptococcus suis Serotype 2 and Serotype 9 Populations. PMID:32029569
Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures. PMID:32029221
Purifying selection of long dsRNA is the first line of defense against false activation of innate immunity. PMID:32028986
Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation. PMID:32027643
Genomic diversity affects the accuracy of bacterial single-nucleotide polymorphism-calling pipelines. PMID:32025702
CitGVD: a comprehensive database of citrus genomic variations. PMID:32025315
A native chromatin immunoprecipitation (ChIP) protocol for studying histone modifications in strawberry fruits. PMID:32025237
Genomic basis for RNA alterations in cancer. PMID:32025019
Butler enables rapid cloud-based analysis of thousands of human genomes. PMID:32024987
Inferring structural variant cancer cell fraction. PMID:32024845
Direct full-length RNA sequencing reveals unexpected transcriptome complexity during Caenorhabditis elegans development. PMID:32024662
The full-length transcriptome of C. elegans using direct RNA sequencing. PMID:32024661
The First Non-LRV RNA Virus in Leishmania. PMID:32024293
Mutation Analysis of Colorectal and Gastric Carcinomas Originating from Adenomas: Insights into Genomic Evolution Associated with Malignant Progression. PMID:32023847
A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability. PMID:32023457
An Ancient Baboon Genome Demonstrates Long-Term Population Continuity in Southern Africa. PMID:32022848
Exon Coverage Variations Between Cancer Tissues and Adjacent Non-Cancerous Tissues are Prognostic Factors in Gastric Cancer. PMID:32021255
Trait associations in the pangenome of pigeon pea (Cajanus cajan). PMID:32020732
Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom. PMID:32020195
Phylogenomic Perspective on a Unique Mycobacterium bovis Clade Dominating Bovine Tuberculosis Infections among Cattle and Buffalos in Northern Brazil. PMID:32019968
A chromosome-scale reference genome for Giardia intestinalis WB. PMID:32019935
Abundance and diversity of resistomes differ between healthy human oral cavities and gut. PMID:32019923
Multiple Loci Control Eyespot Number Variation on the Hindwings of Bicyclus anynana Butterflies. PMID:32019848
AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting. PMID:32019565
Diversity and Host Interactions Among Virulent and Temperate Baltic Sea Flavobacterium Phages. PMID:32019073
Structure-Mediated RNA Decay by UPF1 and G3BP1. PMID:32017897
Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors. PMID:32017710
Evaluating the genome and resistome of extensively drug-resistant Klebsiella pneumoniae using native DNA and RNA Nanopore sequencing. PMID:32016399
REXTAL: Regional Extension of Assemblies Using Linked-Reads. PMID:32016171
An optimized chemical-genetic method for cell-specific metabolic labeling of RNA. PMID:32015544
A new coronavirus associated with human respiratory disease in China. PMID:32015508
The microbiota programs DNA methylation to control intestinal homeostasis and inflammation. PMID:32015497
Standardized phylogenetic and molecular evolutionary analysis applied to species across the microbial tree of life. PMID:32015354
Concentration-Dependent Recruitment of Mammalian Odorant Receptors. PMID:32015097
Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation. PMID:32014431
Previously undetected super-spreading of Mycobacterium tuberculosis revealed by deep sequencing. PMID:32014110
From reads to insight: a hitchhiker's guide to ATAC-seq data analysis. PMID:32014034
Rapid, Paralog-Sensitive CNV Analysis of 2457 Human Genomes Using QuicK-mer2. PMID:32013076
Temporal dynamics of migration-linked genetic variation are driven by streamflows and riverscape permeability. PMID:32012393
Genome-wide analysis of HOXC4 and HOXC6 regulated genes and binding sites in prostate cancer cells. PMID:32012197
Parallel and nonparallel genomic responses contribute to herbicide resistance in Ipomoea purpurea, a common agricultural weed. PMID:32012153
A combined RNA-seq and whole genome sequencing approach for identification of non-coding pathogenic variants in single families. PMID:32011687
Gene copy number is associated with phytochemistry in Cannabis sativa. PMID:32010439
Draft Genome of the Asian Buffalo Leech Hirudinaria manillensis. PMID:32010187
Resequencing 200 Flax Cultivated Accessions Identifies Candidate Genes Related to Seed Size and Weight and Reveals Signatures of Artificial Selection. PMID:32010166
Investigation of Genetic Relationships Between Hanseniaspora Species Found in Grape Musts Revealed Interspecific Hybrids With Dynamic Genome Structures. PMID:32010076
PostSV: A Post-Processing Approach for Filtering Structural Variations. PMID:32009779
Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription. PMID:32006464
Trypanosomatid parasite dynamically changes the transcriptome during infection and modifies honey bee physiology. PMID:32005933
The Role of pkc-3 and Genetic Suppressors in Caenorhabditis elegans Epithelial Cell Junction Formation. PMID:32005655
Genome-wide association study reveals that different pathways contribute to grain quality variation in sorghum (Sorghum bicolor). PMID:32005168
Host-Specific Evolutionary and Transmission Dynamics Shape the Functional Diversification of Staphylococcus epidermidis in Human Skin. PMID:32004459
Chromatin Organization in Early Land Plants Reveals an Ancestral Association between H3K27me3, Transposons, and Constitutive Heterochromatin. PMID:32004456
A cis-carotene derived apocarotenoid regulates etioplast and chloroplast development. PMID:32003746
The characterization of mobile colistin resistance (mcr) genes among 33 000 Salmonella enterica genomes from routine public health surveillance in England. PMID:32003708
Identification of RELN variant p.(Ser2486Gly) in an Iranian family with ankylosing spondylitis; the first association of RELN and AS. PMID:32001840
Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models. PMID:32001719
Plasmid-mediated metronidazole resistance in Clostridioides difficile. PMID:32001686
Deep Sequencing of Urine Specimens Detects Two BK Polyomavirus Genotypes in a Hematopoietic Stem Cell Transplant Recipient. PMID:32001567
MakeHub: Fully Automated Generation of UCSC Genome Browser Assembly Hubs. PMID:32001327
Identification of eQTLs and sQTLs associated with meat quality in beef. PMID:32000679
Transcriptomic analysis of dead end knockout testis reveals germ cell and gonadal somatic factors in Atlantic salmon. PMID:32000659
ATAC-Me Captures Prolonged DNA Methylation of Dynamic Chromatin Accessibility Loci during Cell Fate Transitions. PMID:31999955
Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation. PMID:31998842
Triangular correlation (TrC) between cancer aggressiveness, cell uptake capability, and cell deformability. PMID:31998832
Flow Sorting Enrichment and Nanopore Sequencing of Chromosome 1 From a Chinese Individual. PMID:31998370
Tackling Rapid Radiations With Targeted Sequencing. PMID:31998342
Applying a New REFINE Approach in Zymomonas mobilis Identifies Novel sRNAs That Confer Improved Stress Tolerance Phenotypes. PMID:31998271
Genomic Characterization of a Novel Gut Symbiont From the Hadal Snailfish. PMID:31998265
Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal. PMID:31996844
A single unidirectional piRNA cluster similar to the flamenco locus is the major source of EVE-derived transcription and small RNAs in Aedes aegypti mosquitoes. PMID:31996404
Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients. PMID:31996208
Quasimetagenomic source tracking of Listeria monocytogenes from naturally contaminated ice cream. PMID:31996135
Genomic patterns in the widespread Eurasian lynx shaped by Late Quaternary climatic fluctuations and anthropogenic impacts. PMID:31995648
Exome sequencing of bulked segregants identified a novel TaMKK3-A allele linked to the wheat ERA8 ABA-hypersensitive germination phenotype. PMID:31993676
Population genomics supports clonal reproduction and multiple independent gains and losses of parasitic abilities in the most devastating nematode pest. PMID:31993088
Assessing connectivity despite high diversity in island populations of a malaria mosquito. PMID:31993086
Northern European Salmo trutta (L.) populations are genetically divergent across geographical regions and environmental gradients. PMID:31993085
A population genomics appraisal suggests independent dispersals for bitter and sweet manioc in Brazilian Amazonia. PMID:31993081
Genomic analyses reveal selection footprints in rice landraces grown under on-farm conservation conditions during a short-term period of domestication. PMID:31993077
Resolving the genetic paradox of invasions: Preadapted genomes and postintroduction hybridization of bigheaded carps in the Mississippi River Basin. PMID:31993075
QuantTB - a method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data. PMID:31992201
The complete chloroplast genome of greater duckweed (Spirodela polyrhiza 7498) using PacBio long reads: insights into the chloroplast evolution and transcription regulation. PMID:31992185
Diverse biological processes coordinate the transcriptional response to nutritional changes in a Drosophila melanogaster multiparent population. PMID:31992183
Treatment of a Mouse Model of ALS by In Vivo Base Editing. PMID:31991108
Potential prognostic impact of EBV RNA-seq reads in gastric cancer: a reanalysis of The Cancer Genome Atlas cohort. PMID:31991047
Multiplex gene transfer by genetic transformation between isolated S. pneumoniae cells confined in microfluidic droplets. PMID:31990351
STATR: A simple analysis pipeline of Ribo-Seq in bacteria. PMID:31989542
Association between blooming time and climatic adaptation in Prunus mume. PMID:31988729
Population genomic structure of the gelatinous zooplankton species Mnemiopsis leidyi in its nonindigenous range in the North Sea. PMID:31988713
An RNA polymerase ribozyme that synthesizes its own ancestor. PMID:31988127
Introgression of chromosomal segments conferring early heading date from wheat diploid progenitor, Aegilops tauschii Coss., into Japanese elite wheat cultivars. PMID:31986184
Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia. PMID:31985806
Multiplex exome sequencing reveals genome-wide frequency and distribution of mutations in the 'Micro-Tom' Targeting Induced Local Lesions in Genomes (TILLING) mutant library. PMID:31983876
Tumour suppressive long non-coding RNA AFDN-DT inhibits gastric cancer invasion via transcriptional regulation. PMID:31981317
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA. PMID:31980822
Combined use of gap-PCR and next-generation sequencing improves thalassaemia carrier screening among premarital adults in China. PMID:31980563
CUBIC: an atlas of genetic architecture promises directed maize improvement. PMID:31980033
Osteogenesis imperfecta in a male holstein calf associated with a possible oligogenic origin. PMID:31980012
The Ficus erecta genome aids Ceratocystis canker resistance breeding in common fig (F. carica). PMID:31978270
Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation. PMID:31978041
Identification of sex-linked markers in the sexually cryptic coco de mer: are males and females produced in equal proportions? PMID:31976055
Population Genomics of the House Mouse and the Brown Rat. PMID:31975178
Uncovering tissue-specific binding features from differential deep learning. PMID:31974574
p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis. PMID:31973890
Hypermutation as an Evolutionary Mechanism for Achromobacter xylosoxidans in Cystic Fibrosis Lung Infection. PMID:31973169
Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys. PMID:31971979
Genome-wide analysis reveals a switch in the translational program upon oocyte meiotic resumption. PMID:31970406
Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles. PMID:31969990
Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats. PMID:31969898
Genetic insights into the social organisation of the Avar period elite in the 7th century AD Carpathian Basin. PMID:31969576
Persistent Infection of Simian Foamy Virus Derived from the Japanese Macaque Leads to the High-Level Expression of microRNA that Resembles the miR-1 microRNA Precursor Family. PMID:31969530
Paenibacillus odorifer, the Predominant Paenibacillus Species Isolated from Milk in the United States, Demonstrates Genetic and Phenotypic Conservation of Psychrotolerance but Clade-Associated Differences in Nitrogen Metabolic Pathways. PMID:31969477
Chromosome-Level Assembly of Drosophila bifasciata Reveals Important Karyotypic Transition of the X Chromosome. PMID:31969429
Improved Genome Assembly and Annotation of the Soybean Aphid (Aphis glycines Matsumura). PMID:31969427
Nitrate and Ammonium Affect the Overall Maize Response to Nitrogen Availability by Triggering Specific and Common Transcriptional Signatures in Roots. PMID:31968691
Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens. PMID:31968257
Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells. PMID:31968256
Genome Sequence of Fusarium oxysporum f. sp. matthiolae, a Brassicaceae Pathogen. PMID:31967942
The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani. PMID:31967783
Four high-quality draft genome assemblies of the marine heterotrophic nanoflagellate Cafeteria roenbergensis. PMID:31964893
A chromosome-level reference genome of the hornbeam, Carpinus fangiana. PMID:31964866
A Similar Genetic Architecture Underlies the Convergent Evolution of the Selfing Syndrome in Capsella. PMID:31964802
A Complex Interplay between Nitric Oxide, Quorum Sensing, and the Unique Secondary Metabolite Tundrenone Constitutes the Hypoxia Response in Methylobacter. PMID:31964770
The Tempo and Mode of Angiosperm Mitochondrial Genome Divergence Inferred from Intraspecific Variation in Arabidopsis thaliana. PMID:31964685
5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease. PMID:31964422
Genome-Wide Association Study of Body Weight Traits in Chinese Fine-Wool Sheep. PMID:31963922
Inter- Versus Intra-Host Sequence Diversity of pH1N1 and Associated Clinical Outcomes. PMID:31963512
Analysis of the lineage of Phytophthora infestans isolates using mating type assay, traditional markers, and next generation sequencing technologies. PMID:31961875
Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. PMID:31961865
Oropouche virus cases identified in Ecuador using an optimised qRT-PCR informed by metagenomic sequencing. PMID:31961856
The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter. PMID:31961855
Evolution of Transcriptional Repressors Impacts Caenorhabditis Vulval Development. PMID:31960924
Evaluation of 3D Chromatin Interactions Using Hi-C. PMID:31960372
Candidate genes and gene markers for the resistance to porcine pleuropneumonia. PMID:31960078
Commensal Escherichia coli are a reservoir for the transfer of XDR plasmids into epidemic fluoroquinolone-resistant Shigella sonnei. PMID:31959970
Evolution of a supergene that regulates a trans-species social polymorphism. PMID:31959939
Characterizing the microbiomes of Antarctic sponges: a functional metagenomic approach. PMID:31959785
Characterization of key bacterial species in the Daphnia magna microbiota using shotgun metagenomics. PMID:31959775
Whole exome sequencing identified ATP6V1C2 as a novel candidate gene for recessive distal renal tubular acidosis. PMID:31959358
Auxotrophic mutations of Trichophyton rubrum created by in vitro synthesized Cas9 ribonucleoprotein. PMID:31959181
Comparison of multiple algorithms to reliably detect structural variants in pears. PMID:31959124
The complete mitochondrial genome of Taxus cuspidata (Taxaceae): eight protein-coding genes have transferred to the nuclear genome. PMID:31959109
Demography and Natural Selection Have Shaped Genetic Variation in the Widely Distributed Conifer Norway Spruce (Picea abies). PMID:31958121
Comparative genomics confirms a rare melioidosis human-to-human transmission event and reveals incorrect phylogenomic reconstruction due to polyclonality. PMID:31958055
The somatic mutation landscape of Chinese Colorectal Cancer. PMID:31956350
Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase. PMID:31955845
Stepwise evolution and convergent recombination underlie the global dissemination of carbapenemase-producing Escherichia coli. PMID:31955713
UNAGI: an automated pipeline for nanopore full-length cDNA sequencing uncovers novel transcripts and isoforms in yeast. PMID:31955296
Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients. PMID:31953506
Variation among S-locus haplotypes and among stylar RNases in almond. PMID:31953457
A transcriptome-wide antitermination mechanism sustaining identity of embryonic stem cells. PMID:31953406
High-Quality Genome Assembly and Annotation of the Big-Eye Mandarin Fish (Siniperca knerii). PMID:31953307
Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia. PMID:31951644
Widespread activation of developmental gene expression characterized by PRC1-dependent chromatin looping. PMID:31950077
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer. PMID:31949157
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer. PMID:31949146
Meta-Analysis of Dilated Cardiomyopathy Using Cardiac RNA-Seq Transcriptomic Datasets. PMID:31948008
HIV-1 Unique Recombinant Forms Identified in Slovenia and Their Characterization by Near Full-Length Genome Sequencing. PMID:31947872
Whole Genome Sequencing of Spontaneously Occurring Rat Natural Killer Large Granular Lymphocyte Leukemia Identifies JAK1 Somatic Activating Mutation. PMID:31947841
Bioinformatics and Computational Tools for Next-Generation Sequencing Analysis in Clinical Genetics. PMID:31947757
Deep Sequencing Analysis Reveals Distinctive Non-Coding RNAs When Comparing Tumor Multidrug-Resistant Cells and Extracellular Vesicles with Drug-Sensitive Counterparts. PMID:31947507
Current genetic landscape in common variable immune deficiency. PMID:31942606
Acquisition, transmission and strain diversity of human gut-colonizing crAss-like phages. PMID:31941900
Evasion of a Human Cytomegalovirus Entry Inhibitor with Potent Cysteine Reactivity Is Concomitant with the Utilization of a Heparan Sulfate Proteoglycan-Independent Route of Entry. PMID:31941787
Experimental DNA Demethylation Associates with Changes in Growth and Gene Expression of Oak Tree Seedlings. PMID:31941723
Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. PMID:31940721
p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells. PMID:31940490
Neuroinflammation-Associated Aspecific Manipulation of Mouse Predator Fear by Toxoplasma gondii. PMID:31940479
Biogeographic study of human gut-associated crAssphage suggests impacts from industrialization and recent expansion. PMID:31940321
High-Throughput Single Nucleotide Polymorphism (SNP) Discovery and Validation Through Whole-Genome Resequencing in Nile Tilapia (Oreochromis niloticus). PMID:31938972
Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level. PMID:31937828
Challenges in reporting pathogenic/potentially pathogenic variants in 94 cancer predisposing genes - in pediatric patients screened with NGS panels. PMID:31937788
Network Analysis of the Papaya Orchard Virome from Two Agroecological Regions of Chiapas, Mexico. PMID:31937673
Tissue-specific changes in the RNA structurome mediate salinity response in Arabidopsis. PMID:31937672
Intraspecific diversification of the crop wild relative Brassica cretica Lam. using demographic model selection. PMID:31937246
Placental effects on the maternal brain revealed by disrupted placental gene expression in mouse hybrids. PMID:31937228
Mitochondrial DNA Variation and Selfish Propagation Following Experimental Bottlenecking in Two Distantly Related Caenorhabditis briggsae Isolates. PMID:31936803
A Genome-Wide Association Study Identifies Quantitative Trait Loci Affecting Hematological Traits in Camelus bactrianus. PMID:31936121
Transcriptome Analysis Reveals Potential Regulatory Genes Related to Heat Tolerance in Holstein Dairy Cattle. PMID:31936116
Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer. PMID:31935636
Lola regulates Drosophila adult midgut homeostasis via non-canonical hippo signaling. PMID:31934851
Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease. PMID:31934626
sv-callers: a highly portable parallel workflow for structural variant detection in whole-genome sequence data. PMID:31934500
Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype. PMID:31934344
Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection. PMID:31932810
Transcript specific regulation of expression influences susceptibility to multiple sclerosis. PMID:31932686
Reciprocal cybrids reveal how organellar genomes affect plant phenotypes. PMID:31932677
LAX28 is required for the stable assembly of the inner dynein arm f complex, and the tether and tether head complex in Leishmania flagella. PMID:31932510
Unraveling the Hierarchy of cis and trans Factors That Determine the DNA Binding by Peroxisome Proliferator-Activated Receptor γ. PMID:31932484
Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification. PMID:31931956
Gene regulatory response to hyposalinity in the brown seaweed Fucus vesiculosus. PMID:31931708
Development and characterization of an EMS-mutagenized wheat population and identification of salt-tolerant wheat lines. PMID:31931695
Immunomodulatory function of the cystic fibrosis modifier gene BPIFA1. PMID:31931521
Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor. PMID:31930715
Genome ancestry mosaics reveal multiple and cryptic contributors to cultivated banana. PMID:31930580
FilTar: using RNA-Seq data to improve microRNA target prediction accuracy in animals. PMID:31930382
RiboFlow, RiboR and RiboPy: an ecosystem for analyzing ribosome profiling data at read length resolution. PMID:31930375
Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory disease. PMID:31929561
Genomic profiling of multiple breast cancer reveals inter-lesional heterogeneity. PMID:31929516
Identification of Candidate Growth-Related SNPs and Genes Using GWAS in Brown-Marbled Grouper (Epinephelus fuscoguttatus). PMID:31927644
Germline mutation of TSC1 or TSC2 gene in Chinese patients with bilateral renal angiomyolipomas and mutation spectrum of Chinese TSC patients. PMID:31927531
Fine mapping of the male fertility restoration gene CaRf032 in Capsicum annuum L. PMID:31925462
SCDC: bulk gene expression deconvolution by multiple single-cell RNA sequencing references. PMID:31925417
Whole-genome sequencing of 128 camels across Asia reveals origin and migration of domestic Bactrian camels. PMID:31925316
Cytosine base editor 4 but not adenine base editor generates off-target mutations in mouse embryos. PMID:31925293
Plant metabolism of nematode pheromones mediates plant-nematode interactions. PMID:31924834
Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing. PMID:31924754
Vanillin Production in Pseudomonas: Whole-Genome Sequencing of Pseudomonas sp. Strain 9.1 and Reannotation of Pseudomonas putida CalA as a Vanillin Reductase. PMID:31924622
Clinical, cytogenetic and molecular genetic characterization of a tandem fusion translocation in a male Holstein cattle with congenital hypospadias and a ventricular septal defect. PMID:31923267
Brief communication: Long-term absence of Langerhans cells alters the gene expression profile of keratinocytes and dendritic epidermal T cells. PMID:31923202
Mutations on ent-kaurene oxidase 1 encoding gene attenuate its enzyme activity of catalyzing the reaction from ent-kaurene to ent-kaurenoic acid and lead to delayed germination in rice. PMID:31923187
ABEMUS: platform-specific and data-informed detection of somatic SNVs in cfDNA. PMID:31922552
Large-scale and significant expression from pseudogenes in Sodalis glossinidius - a facultative bacterial endosymbiont. PMID:31922467
The genetic mechanism of selfishness and altruism in parent-offspring coadaptation. PMID:31922000
Machine learning applied to whole-blood RNA-sequencing data uncovers distinct subsets of patients with systemic lupus erythematosus. PMID:31921420
TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling. PMID:31921404
Transcriptome Profiling Predicts New Genes to Promote Maize Callus Formation and Transformation. PMID:31921272
The Landscape of Copia and Gypsy Retrotransposon During Maize Domestication and Improvement. PMID:31921227
Rainbow Trout IgM+ B Cells Preferentially Respond to Thymus-Independent Antigens but Are Activated by CD40L. PMID:31921163
Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo. PMID:31921150
Detailed Evaluation of Data Analysis Tools for Subtyping of Bacterial Isolates Based on Whole Genome Sequencing: Neisseria meningitidis as a Proof of Concept. PMID:31921072
IS26-Mediated Transfer of bla NDM-1 as the Main Route of Resistance Transmission During a Polyclonal, Multispecies Outbreak in a German Hospital. PMID:31921015
Dispersal of Mycobacterium tuberculosis Driven by Historical European Trade in the South Pacific. PMID:31921003
Identification and fine mapping of qSB.A09, a major QTL that controls shoot branching in Brassica rapa ssp. chinensis Makino. PMID:31919538
A susceptibility biomarker identification strategy based on significantly differentially expressed ceRNA triplets for ischemic cardiomyopathy. PMID:31919492
Complete Genome Sequences of 13 Bacillus subtilis Soil Isolates for Studying Secondary Metabolite Diversity. PMID:31919181
Complete Genome Sequences, Derived by Next-Generation Sequencing, of JC Polyomavirus Strains Isolated from Vietnamese Renal Transplant Recipients. PMID:31919176
Metagenome Sequences from the Environment of Diseased Otter Clams, Lutraria rhynchaena, from a Farm in Vietnam. PMID:31919158
Genomic Sequencing To Identify Potential Causative Mutation(s) of Neurospora crassa col-4. PMID:31919156
Transcriptome-Wide Patterns of the Genetic and Expression Variations in Two Sympatric Schizothoracine Fishes in a Tibetan Plateau Glacier Lake. PMID:31917411
High-resolution expression profiling of selected gene sets during plant immune activation. PMID:31916350
Using TTchem-seq for profiling nascent transcription and measuring transcript elongation. PMID:31915390
TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. PMID:31915377
Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types. PMID:31915147
Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data. PMID:31915011
Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. PMID:31914399
The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections. PMID:31914379
Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome. PMID:31914175
Dynamic and regulated TAF gene expression during mouse embryonic germ cell development. PMID:31914128
Characteristics of induced mutations in offspring derived from irradiated mouse spermatogonia and mature oocytes. PMID:31913321
5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus. PMID:31913284
The Mouse Gut Microbial Biobank expands the coverage of cultured bacteria. PMID:31911589
Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains. PMID:31911579
Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy. PMID:31911545
Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance. PMID:31910889
Chromatin interactome mapping at 139 independent breast cancer risk signals. PMID:31910858
Anti-masculinization induced by aromatase inhibitors in adult female zebrafish. PMID:31910818
Network analysis of human muscle adaptation to aging and contraction. PMID:31910159
The genetic basis of aneuploidy tolerance in wild yeast. PMID:31909711
Dataset for transcriptome analysis of abscisic acid degrading bacterium Novosphingobium sp. P6W. PMID:31909107
Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. PMID:31908356
The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins. PMID:31907489
Accurate detection of mosaic variants in sequencing data without matched controls. PMID:31907404
Genetic analysis of pleomorphic and florid lobular carcinoma in situ variants: frequent ERBB2/ERBB3 alterations and clonal relationship to classic lobular carcinoma in situ and invasive lobular carcinoma. PMID:31907376
Tumoral and immune heterogeneity in an anti-PD-1-responsive glioblastoma: a case study. PMID:31907277
Characterizing the ribosomal tandem repeat and its utility as a DNA barcode in lichen-forming fungi. PMID:31906844
Consensify: A Method for Generating Pseudohaploid Genome Sequences from Palaeogenomic Datasets with Reduced Error Rates. PMID:31906474
Molecular Mapping and Candidate Gene Analysis for GA3 Responsive Short Internode in Watermelon (Citrullus lanatus). PMID:31906246
Heritability of interpack aggression in a wild pedigreed population of North American grey wolves. PMID:31905256
CIRCexplorer3: A CLEAR Pipeline for Direct Comparison of Circular and Linear RNA Expression. PMID:31904419
Characterization of a Y-specific duplication/insertion of the anti-Mullerian hormone type II receptor gene based on a chromosome-scale genome assembly of yellow perch, Perca flavescens. PMID:31903688
Fidelity of translation initiation is required for coordinated respiratory complex assembly. PMID:31903419
Molecular characterization and distribution of the voltage-gated sodium channel, Para, in the brain of the grasshopper and vinegar fly. PMID:31902005
Exploitation of the Cooperative Behaviors of Anti-CRISPR Phages. PMID:31901522
Su(var)2-10 and the SUMO Pathway Link piRNA-Guided Target Recognition to Chromatin Silencing. PMID:31901446
Contribution of introns to the species diversity associated with the apicomplexan parasite, Neospora caninum. PMID:31901106
Construction of a High-Density Genetic Linkage Map and QTL Mapping for Growth-Related Traits in Takifugu bimaculatus. PMID:31900733
Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans. PMID:31900453
Novel genomic resources for shelled pteropods: a draft genome and target capture probes for Limacina bulimoides, tested for cross-species relevance. PMID:31900119
Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies. PMID:31898513
Construction of High-Density Genetic Map and Mapping of Sex-Related Loci in the Yellow Catfish (Pelteobagrus fulvidraco). PMID:31897745
Organohalide-respiring Desulfoluna species isolated from marine environments. PMID:31896791
TCTEX1D1 is a genetic modifier of disease progression in Duchenne muscular dystrophy. PMID:31896777
Complete Genome Sequence of Campylobacter armoricus CA639, Which Carries Two Plasmids, Compiled Using Oxford Nanopore and Illumina Sequencing Technologies. PMID:31896644
Insights into the Gene Expression Profiles of Active and Restricted Red/Green-HIV+ Human Astrocytes: Implications for Shock or Lock Therapies in the Brain. PMID:31896591
Analysis of unmapped regions associated with long deletions in Korean whole genome sequences based on short read data. PMID:31896240
Genome and population sequencing of a chromosome-level genome assembly of the Chinese tapertail anchovy (Coilia nasus) provides novel insights into migratory adaptation. PMID:31895412
Aegilops umbellulata introgression carrying leaf rust and stripe rust resistance genes Lr76 and Yr70 located to 9.47-Mb region on 5DS telomeric end through a combination of chromosome sorting and sequencing. PMID:31894365
Structural genome analysis in cultivated potato taxa. PMID:31893289
Optimizing genomic selection for blight resistance in American chestnut backcross populations: A trade-off with American chestnut ancestry implies resistance is polygenic. PMID:31892942
Long walk to genomics: History and current approaches to genome sequencing and assembly. PMID:31890139
Duplication and parallel evolution of the pancreatic ribonuclease gene (RNASE1) in folivorous non-colobine primates, the howler monkeys (Alouatta spp.). PMID:31889139
Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia. PMID:31889055
Impact of Early Antiretroviral Therapy Initiation on HIV-Specific CD4 and CD8 T Cell Function in Perinatally Infected Children. PMID:31889024
Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis. PMID:31888773
mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity. PMID:31888698
Construction of a high-density genetic map and QTL mapping of leaf traits and plant growth in an interspecific F1 population of Catalpa bungei × Catalpa duclouxii Dode. PMID:31888555
SMaSH: Sample matching using SNPs in humans. PMID:31888490
An ancestry informative marker panel design for individual ancestry estimation of Hispanic population using whole exome sequencing data. PMID:31888480
Genome sequencing of Mycobacterium pinnipedii strains: genetic characterization and evidence of superinfection in a South American sea lion (Otaria flavescens). PMID:31888476
Cloud accelerated alignment and assembly of full-length single-cell RNA-seq data using Falco. PMID:31888474
Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue transcriptomic approach. PMID:31888468
Genetic variation drives seasonal onset of hibernation in the 13-lined ground squirrel. PMID:31886416
The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae. PMID:31885205
Multi-species annotation of transcriptome and chromatin structure in domesticated animals. PMID:31884969
PRC1 Catalytic Activity Is Central to Polycomb System Function. PMID:31883950
Patterns of Hybrid Seed Inviability in the Mimulus guttatus sp. Complex Reveal a Potential Role of Parental Conflict in Reproductive Isolation. PMID:31883810
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. PMID:31883794
Near-Random Distribution of Chromosome-Derived Circular DNA in the Condensed Genome of Pigeons and the Larger, More Repeat-Rich Human Genome. PMID:31882998
High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls. PMID:31882973
Fetal androgen exposure is a determinant of adult male metabolic health. PMID:31882954
Genome-Wide SNP discovery and genomic characterization in avocado (Persea americana Mill.). PMID:31882769
The host generalist phytopathogenic fungus Sclerotinia sclerotiorum differentially expresses multiple metabolic enzymes on two different plant hosts. PMID:31882688
Cost-effective detection of genome-wide signatures for 2,4-D herbicide resistance adaptation in red clover. PMID:31882573
A rapid and label-free platform for virus capture and identification from clinical samples. PMID:31882450
Oscillatory cAMP signaling rapidly alters H3K4 methylation. PMID:31882444
Synaptonemal Complex-Deficient Drosophila melanogaster Females Exhibit Rare DSB Repair Events, Recurrent Copy-Number Variation, and an Increased Rate of de Novo Transposable Element Movement. PMID:31882405
Mating-Type-Specific Ribosomal Proteins Control Aspects of Sexual Reproduction in Cryptococcus neoformans. PMID:31882399
LEMON: a method to construct the local strains at horizontal gene transfer sites in gut metagenomics. PMID:31881904
Gencore: an efficient tool to generate consensus reads for error suppressing and duplicate removing of NGS data. PMID:31881822
Investigating unexplained genetic variation and its expression in the arbuscular mycorrhizal fungus Rhizophagus irregularis: A comparison of whole genome and RAD sequencing data. PMID:31881076
Scalable and cost-effective ribonuclease-based rRNA depletion for transcriptomics. PMID:31879761
Benchmarking protocols for the metagenomic analysis of stream biofilm viromes. PMID:31879573
PaCBAM: fast and scalable processing of whole exome and targeted sequencing data. PMID:31878881
Archaic mitochondrial DNA inserts in modern day nuclear genomes. PMID:31878873
Molecular Signature of Subtypes of Non-Small-Cell Lung Cancer by Large-Scale Transcriptional Profiling: Identification of Key Modules and Genes by Weighted Gene Co-Expression Network Analysis (WGCNA). PMID:31877723
Study of congenital Morgagnian cataracts in Holstein calves. PMID:31877171
Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue Disease. PMID:31875555
Targeting of the Dosage-Compensated Male X-Chromosome during Early Drosophila Development. PMID:31875538
Biomarker potential of repetitive-element transcriptome in lung cancer. PMID:31875158
The somatic mutation landscape of the human body. PMID:31874648
Comparison of somatic variant detection algorithms using Ion Torrent targeted deep sequencing data. PMID:31874647
Antimicrobial resistance genetic factor identification from whole-genome sequence data using deep feature selection. PMID:31874612
Integrative transcriptome analysis discloses the molecular basis of a heterogeneous fungal phytopathogen complex, Rhizoctonia solani AG-1 subgroups. PMID:31873088
Rice Stress-Resistant SNP Database. PMID:31872320
Widespread roles for piRNAs and WAGO-class siRNAs in shaping the germline transcriptome of Caenorhabditis elegans. PMID:31872227
Divergent selection and drift shape the genomes of two avian sister species spanning a saline-freshwater ecotone. PMID:31871659
Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing. PMID:31870437
Root system traits impact early fire blight susceptibility in apple (Malus × domestica). PMID:31870310
A novel de novo dominant mutation of NOTCH1 gene in an Iranian family with non-syndromic congenital heart disease. PMID:31867804
Genome-wide discovery of SNPs in candidate genes related to production and fertility traits in Sahiwal cattle. PMID:31867700
Domesticating Vigna Stipulacea: A Potential Legume Crop With Broad Resistance to Biotic Stresses. PMID:31867036
Genomic Features of Rickettsia heilongjiangensis Revealed by Intraspecies Comparison and Detailed Comparison With Rickettsia japonica. PMID:31866968
Comparison of the transcriptomes of two tardigrades with different hatching coordination. PMID:31864287
Characterization of cancer omics and drug perturbations in panels of lung cancer cells. PMID:31863083
De novo Assembly of the Brugia malayi Genome Using Long Reads from a Single MinION Flowcell. PMID:31863009
Computational discovery of hidden breaks in 28S ribosomal RNAs across eukaryotes and consequences for RNA Integrity Numbers. PMID:31863008
Small Molecules Produced by Commensal Staphylococcus epidermidis Disrupt Formation of Biofilms by Staphylococcus aureus. PMID:31862721
A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism. PMID:31862442
Combinatorial action of NF-Y and TALE at embryonic enhancers defines distinct gene expression programs during zygotic genome activation in zebrafish. PMID:31862379
PIRCh-seq: functional classification of non-coding RNAs associated with distinct histone modifications. PMID:31862000
Intraspecific Diversity in the Cold Stress Response of Transposable Elements in the Diatom Leptocylindrus aporus. PMID:31861932
Comparative Analysis and Expression Patterns of the PLP_deC Genes in Dendrobium officinale. PMID:31861760
Functionally Annotating Regulatory Elements in the Equine Genome Using Histone Mark ChIP-Seq. PMID:31861495
Comparative Pangenomics of the Mammalian Gut Commensal Bifidobacterium longum. PMID:31861401
Homburgvirus LP-018 Has a Unique Ability to Infect Phage-Resistant Listeria monocytogenes. PMID:31861087
Comparative genomic analysis identifies X-factor (haemin)-independent Haemophilus haemolyticus: a formal re-classification of 'Haemophilus intermedius'. PMID:31860436
Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and -independent regulatory pathways. PMID:31859607
De Novo Assembly of a High-Quality Reference Genome for the Horned Lark (Eremophila alpestris). PMID:31857331
Paragraph: a graph-based structural variant genotyper for short-read sequence data. PMID:31856913
Nickel-induced transcriptional changes persist post exposure through epigenetic reprogramming. PMID:31856895
Fast read alignment with incorporation of known genomic variants. PMID:31856811
Variation in plastid genomes in the gynodioecious species Silene vulgaris. PMID:31856730
Targeted sequencing of the LRRTM gene family in suicide attempters with bipolar disorder. PMID:31854516
A Germline Mutation in the C2 Domain of PLCγ2 Associated with Gain-of-Function Expands the Phenotype for PLCG2-Related Diseases. PMID:31853824
Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology. PMID:31853540
Sensitivity and specificity of metatranscriptomics as an arbovirus surveillance tool. PMID:31852942
Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues. PMID:31852848
Ebola Virus Produces Discrete Small Noncoding RNAs Independently of the Host MicroRNA Pathway Which Lack RNA Interference Activity in Bat and Human Cells. PMID:31852785
Optimizing DNA Extraction Methods for Nanopore Sequencing of Neisseria gonorrhoeae Directly from Urine Samples. PMID:31852766
SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα. PMID:31851938
Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids. PMID:31851934
Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics. PMID:31851607
Rational genomic optimization of DNA detection for human papillomavirus type 16 in head and neck squamous cell carcinoma. PMID:31850594
Detection of a Frameshift Deletion in the SPTBN4 Gene Leads to Prevention of Severe Myopathy and Postnatal Mortality in Pigs. PMID:31850074
Increased Adaptive Variation Despite Reduced Overall Genetic Diversity in a Rapidly Adapting Invader. PMID:31850072
Thermal Manipulation During Embryogenesis Impacts H3K4me3 and H3K27me3 Histone Marks in Chicken Hypothalamus. PMID:31850067
Whole Genome Resequencing Reveals Selection Signatures Associated With Important Traits in Ethiopian Indigenous Goat Populations. PMID:31850061
Pervasive Inter-Individual Variation in Allele-Specific Expression in Monozygotic Twins. PMID:31850058
Sucrose Starvation Induces Microautophagy in Plant Root Cells. PMID:31850051
Expression QTL (eQTLs) Analyses Reveal Candidate Genes Associated With Fruit Flesh Softening Rate in Peach [Prunus persica (L.) Batsch]. PMID:31850046
Genome-Wide Comparisons of Mutations Induced by Carbon-Ion Beam and Gamma-Rays Irradiation in Rice via Resequencing Multiple Mutants. PMID:31850019
Neoantigen Fitness Model Predicts Lower Immune Recognition of Cutaneous Squamous Cell Carcinomas Than Actinic Keratoses. PMID:31849976
Whole Genome Re-sequencing Reveals Natural Variation and Adaptive Evolution of Phytophthora sojae. PMID:31849921
Small RNA ArcZ Regulates Oxidative Stress Response Genes and Regulons in Erwinia amylovora. PMID:31849909
TRITEX: chromosome-scale sequence assembly of Triticeae genomes with open-source tools. PMID:31849336
Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type. PMID:31849330
Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis. PMID:31848386
A transposable element insertion is associated with an alternative life history strategy. PMID:31848330
Global Screening of Genomic and Transcriptomic Factors Associated with Phenotype Differences between Multidrug-Resistant and -Susceptible Candida haemulonii Strains. PMID:31848301
Host-Microbe Interactions in the Chemosynthetic Riftia pachyptila Symbiosis. PMID:31848270
Towards standardisation: comparison of five whole genome sequencing (WGS) analysis pipelines for detection of epidemiologically linked tuberculosis cases. PMID:31847944
FIREVAT: finding reliable variants without artifacts in human cancer samples using etiologically relevant mutational signatures. PMID:31847917
The Peptide Venom Composition of the Fierce Stinging Ant Tetraponera aethiops (Formicidae: Pseudomyrmecinae). PMID:31847368
Conjunctive Analyses of BSA-Seq and BSR-Seq to Reveal the Molecular Pathway of Leafy Head Formation in Chinese Cabbage. PMID:31847231
Next Generation Sequencing in Newborn Screening in the United Kingdom National Health Service. PMID:31844782
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells. PMID:31844323
Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans. PMID:31844068
SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies. PMID:31842948
Transcriptome-wide association study identifies putative elicitors/suppressor of Puccinia graminis f. sp. tritici that modulate barley rpg4-mediated stem rust resistance. PMID:31842749
Recovering rearranged cancer chromosomes from karyotype graphs. PMID:31842730
Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking. PMID:31841597
Hybridization promotes asexual reproduction in Caenorhabditis nematodes. PMID:31841515
Selection signatures in goats reveal copy number variants underlying breed-defining coat color phenotypes. PMID:31841508
Whole genome sequencing and novel candidate genes for CAKUT and altered nephrogenesis in the HSRA rat. PMID:31841396
Genetic susceptibility to severe childhood asthma and rhinovirus-C maintained by balancing selection in humans for 150 000 years. PMID:31841129
The torpedo effect in Bacillus subtilis: RNase J1 resolves stalled transcription complexes. PMID:31840842
Ecogenomics of the SAR11 clade. PMID:31840364
High intrinsic hydrolytic activity of cyanobacterial RNA polymerase compensates for the absence of transcription proofreading factors. PMID:31840183
Genomic architecture of parallel ecological divergence: Beyond a single environmental contrast. PMID:31840052
Bioinformatics Workflows With NoSQL Database in Cloud Computing. PMID:31839702
Splicing Kinetics and Coordination Revealed by Direct Nascent RNA Sequencing through Nanopores. PMID:31839405
The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions. PMID:31837996
Retrospective Validation of a Metagenomic Sequencing Protocol for Combined Detection of RNA and DNA Viruses Using Respiratory Samples from Pediatric Patients. PMID:31837435
SGID: a comprehensive and interactive database of the silkworm. PMID:31836898
Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients. PMID:31836714
Molecular determinants of nephron vascular specialization in the kidney. PMID:31836710
hsa-miR-9-3p and hsa-miR-9-5p as Post-Transcriptional Modulators of DNA Topoisomerase IIα in Human Leukemia K562 Cells with Acquired Resistance to Etoposide. PMID:31836624
Heterogeneous alteration of the ERBB3-MYC axis associated with MEK inhibitor resistance in a KRAS-mutated low-grade serous ovarian cancer patient. PMID:31836588
Methicillin-Resistant Staphylococcus aureus Strains in Swiss Pigs and Their Relation to Isolates from Farmers and Veterinarians. PMID:31836575
Proteo-Transcriptomic Characterization of the Venom from the Endoparasitoid Wasp Pimpla turionellae with Aspects on Its Biology and Evolution. PMID:31835557
Charting the Complexity of the Marine Microbiome through Single-Cell Genomics. PMID:31835036
An Annotated Draft Genome of the Mountain Hare (Lepus timidus). PMID:31834364
Platform-integrated mRNA isoform quantification. PMID:31834359
Parental origin of the allotetraploid tobacco Nicotiana benthamiana. PMID:31833111
Whole-genome resequencing analysis of 20 Micro-pigs. PMID:31833050
The genome of Chenopodium pallidicaule: An emerging Andean super grain. PMID:31832282
Multiple freshwater invasions of the tapertail anchovy (Clupeiformes: Engraulidae) of the Yangtze River. PMID:31832154
Reverse Phenotyping after Whole-Exome Sequencing in Steroid-Resistant Nephrotic Syndrome. PMID:31831576
DeepSV: accurate calling of genomic deletions from high-throughput sequencing data using deep convolutional neural network. PMID:31830921
Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads. PMID:31830908
A developmental landscape of 3D-cultured human pre-gastrulation embryos. PMID:31830756
Male-specific association of the 2p25 region with suicide attempt in bipolar disorder. PMID:31830721
Functional Genomics of a Symbiotic Community: Shared Traits in the Olive Fruit Fly Gut Microbiota. PMID:31830246
Straightjacket/α2δ3 deregulation is associated with cardiac conduction defects in myotonic dystrophy type 1. PMID:31829940
In Vitro Susceptibility and Florfenicol Resistance in Citrobacter Isolates and Whole-Genome Analysis of Multidrug-Resistant Citrobacter freundii. PMID:31828082
Effects of marker type and filtering criteria on Q ST-F ST comparisons. PMID:31827824
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. PMID:31827283
HBO1 is required for the maintenance of leukaemia stem cells. PMID:31827282
Tempo and mode of allopatric divergence in the weakly electric fish Sternopygus dariensis in the Isthmus of Panama. PMID:31827183
Diversity of P1 phage-like elements in multidrug resistant Escherichia coli. PMID:31827120
Genome-Wide Association Mapping and Gene Expression Analyses Reveal Genetic Mechanisms of Disease Resistance Variations in Cynoglossus semilaevis. PMID:31824570
Biological Network Approach for the Identification of Regulatory Long Non-Coding RNAs Associated With Metabolic Efficiency in Cattle. PMID:31824560
Analyses of Plastome Sequences Improve Phylogenetic Resolution and Provide New Insight Into the Evolutionary History of Asian Sonerileae/Dissochaeteae. PMID:31824528
miR824/AGAMOUS-LIKE16 Module Integrates Recurring Environmental Heat Stress Changes to Fine-Tune Poststress Development. PMID:31824525
High-Density Genetic Map Construction and QTL Mapping of Leaf and Needling Traits in Ziziphus jujuba Mill. PMID:31824522
Shedding Light on Specificity: Population Genomic Structure of a Symbiosis Between a Coral Reef Fish and Luminous Bacterium. PMID:31824455
The mitochondrial transcriptome of the anglerfish Lophius piscatorius. PMID:31823814
Targeted deep-intronic sequencing in a cohort of unexplained cases of suspected Lynch syndrome. PMID:31822864
Characterization of novel genetic alterations in salivary gland secretory carcinoma. PMID:31822803
Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease. PMID:31822667
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia. PMID:31821784
A High-Quality Reference Genome Assembly of the Saltwater Crocodile, Crocodylus porosus, Reveals Patterns of Selection in Crocodylidae. PMID:31821505
Evolutionary Dynamics of Structural Variation at a Key Locus for Color Pattern Diversification in Cichlid Fishes. PMID:31821504
Discovery of genomic variations by whole-genome resequencing of the North American Araucana chicken. PMID:31821332
Identification of soybean drought-tolerant genotypes and loci correlated with agronomic traits contributes new candidate genes for breeding. PMID:31820285
Novel mutations in c2orf71 causing an early onset form of cone-rod dystrophy: A molecular diagnosis after 20 years of clinical follow-up. PMID:31819343
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. PMID:31819276
The functional landscape of the human phosphoproteome. PMID:31819260
A comprehensive resource for retrieving, visualizing, and integrating functional genomics data. PMID:31818883
Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells. PMID:31818882
Differential gene expression among three sex types reveals a MALE STERILITY 1 (CpMS1) for sex differentiation in papaya. PMID:31818257
Grapevine Phyllosphere Community Analysis in Response to Elicitor Application against Powdery Mildew. PMID:31817902
Rapid, Unbiased PRRSV Strain Detection Using MinION Direct RNA Sequencing and Bioinformatics Tools. PMID:31817886
Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model. PMID:31815961
BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening. PMID:31815044
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A. PMID:31814998
A point mutation resulting in a 13 bp deletion in the coding sequence of Cldf leads to a GA-deficient dwarf phenotype in watermelon. PMID:31814985
A Novel de novo KIF1A Mutation in a Patient with Autism, Hyperactivity, Epilepsy, Sensory Disturbance, and Spastic Paraplegia. PMID:31813911
In silico prediction of high-resolution Hi-C interaction matrices. PMID:31811132
Identification of African-Specific Admixture between Modern and Archaic Humans. PMID:31809748
Recapitulation-like developmental transitions of chromatin accessibility in vertebrates. PMID:31807314
De Novo Genome Assembly of Populus simonii Further Supports That Populus simonii and Populus trichocarpa Belong to Different Sections. PMID:31806765
Single-nucleus chromatin accessibility reveals intratumoral epigenetic heterogeneity in IDH1 mutant gliomas. PMID:31806013
Integrating long noncoding RNAs and mRNAs expression profiles of response to Plasmodiophora brassicae infection in Pakchoi (Brassica campestris ssp. chinensis Makino). PMID:31805057
Whole genome sequencing of Entamoeba nuttalli reveals mammalian host-related molecular signatures and a novel octapeptide-repeat surface protein. PMID:31805050
popSTR2 enables clinical and population-scale genotyping of microsatellites. PMID:31804671
Comparative analysis of corrected tiger genome provides clues to its neuronal evolution. PMID:31804567
Common genetic variants associated with Parkinson's disease display widespread signature of epigenetic plasticity. PMID:31804560
The Local South American Chicken Populations Are a Melting-Pot of Genomic Diversity. PMID:31803242
Genome Wide Association Study and Genomic Selection of Amino Acid Concentrations in Soybean Seeds. PMID:31803203
Monitoring Aspergillus flavus Genotypes in a Multi-Genotype Aflatoxin Biocontrol Product With Quantitative Pyrosequencing. PMID:31803149
Systematic evaluation of differential splicing tools for RNA-seq studies. PMID:31802105
Light-driven anaerobic microbial oxidation of manganese. PMID:31802001
The molecular landscape of ETMR at diagnosis and relapse. PMID:31802000
Key role for CTCF in establishing chromatin structure in human embryos. PMID:31801998
Influenza B Viruses Exhibit Lower Within-Host Diversity than Influenza A Viruses in Human Hosts. PMID:31801858
Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris). PMID:31801527
Genome-wide analysis of the H3K27me3 epigenome and transcriptome in Brassica rapa. PMID:31800038
Mapping RNA-capsid interactions and RNA secondary structure within virus particles using next-generation sequencing. PMID:31799606
Identification of novel genetic variants predisposing to familial oral squamous cell carcinomas. PMID:31798960
Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss. PMID:31798899
A Single Nucleotide Deletion in an ABC Transporter Gene Leads to a Dwarf Phenotype in Watermelon. PMID:31798601
Genotyping-by-Sequencing of Gossypium hirsutum Races and Cultivars Uncovers Novel Patterns of Genetic Relationships and Domestication Footprints. PMID:31798299
Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys. PMID:31797925
Antibiotic-induced microbiome perturbations are associated with significant alterations to colonic mucosal immunity in rhesus macaques. PMID:31797911
Integrating a genome-wide association study with transcriptomic analysis to detect genes controlling grain drying rate in maize (Zea may, L.). PMID:31797010
Differences in MHC-B diversity and KIR epitopes in two populations of wild chimpanzees. PMID:31797008
Population genomics of two congeneric Palaearctic shorebirds reveals differential impacts of Quaternary climate oscillations across habitats types. PMID:31796810
Epigenomic dysregulation-mediated alterations of key biological pathways and tumor immune evasion are hallmarks of gingivo-buccal oral cancer. PMID:31796082
Weighted gene co-expression network analysis unveils gene networks associated with the Fusarium head blight resistance in tetraploid wheat. PMID:31795948
Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma. PMID:31795494
Contribution of a Novel B3GLCT Variant to Peters Plus Syndrome Discovered by a Combination of Next-Generation Sequencing and Automated Text Mining. PMID:31795264
Simultaneous Monitoring of Mutation and Chimerism Using Next-Generation Sequencing in Myelodysplastic Syndrome. PMID:31795155
Parallel Bud Mutation Sequencing Reveals that Fruit Sugar and Acid Metabolism Potentially Influence Stress in Malus. PMID:31795097
Widespread subcortical grey matter degeneration in primary lateral sclerosis: a multimodal imaging study with genetic profiling. PMID:31795059
Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle. PMID:31794382
Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability. PMID:31794024
Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages. PMID:31792380
Muropeptides Stimulate Growth Resumption from Stationary Phase in Escherichia coli. PMID:31792329
Dark-Induced Senescence Causes Localized Changes in DNA Methylation. PMID:31792150
Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures. PMID:31791392
Autosomal-dominant hypotrichosis with woolly hair: Novel gene locus on chromosome 4q35.1-q35.2. PMID:31790498
Effects of Common and Rare Chromosome 4 GABAergic Gene Variation on Alcohol Use and Antisocial Behavior. PMID:31790348
Seed comparative genomics in three coffee species identify desiccation tolerance mechanisms in intermediate seeds. PMID:31790120
Applying a Linear Amplification Strategy to Recombinase Polymerase Amplification for Uniform DNA Library Amplification. PMID:31788628
Identification of novel genes associated with litter size of indigenous sheep population in Xinjiang, China using specific-locus amplified fragment sequencing technology. PMID:31788357
Predicting the success of an invader: Niche shift versus niche conservatism. PMID:31788205
High-throughput long paired-end sequencing of a Fosmid library by PacBio. PMID:31788019
Enrichment of Marinobacter sp. and Halophilic Homoacetogens at the Biocathode of Microbial Electrosynthesis System Inoculated With Red Sea Brine Pool. PMID:31787955
Intestinal microbiota domination under extreme selective pressures characterized by metagenomic read cloud sequencing and assembly. PMID:31787070
HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. PMID:31786140
A Novel Field-Deployable Method for Sequencing and Analyses of Henipavirus Genomes From Complex Samples on the MinION Platform. PMID:31784761
Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia. PMID:31784538
Programmed DNA elimination of germline development genes in songbirds. PMID:31784533
Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β. PMID:31784499
MeCP2 Represses the Rate of Transcriptional Initiation of Highly Methylated Long Genes. PMID:31784358
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria. PMID:31784259
Comparative genomics of Mycoplasma pneumoniae isolated from children with pneumonia: South Korea, 2010-2016. PMID:31783732
Assembly of the 373k gene space of the polyploid sugarcane genome reveals reservoirs of functional diversity in the world's leading biomass crop. PMID:31782791
Exome association analysis sheds light onto leaf rust (Puccinia triticina) resistance genes currently used in wheat breeding (Triticum aestivum L.). PMID:31782598
Dynamic Changes of DNA Methylation and Transcriptome Expression in Porcine Ovaries during Aging. PMID:31781648
A Missense Mutation in OPA1 Causes Dominant Optic Atrophy in a Chinese Family. PMID:31781369
A Cohesin Subunit Variant Identified from a Peripheral Sclerocornea Pedigree. PMID:31781308
Transcriptome and Volatilome Analysis During Growth of Brochothrix thermosphacta in Food: Role of Food Substrate and Strain Specificity for the Expression of Spoilage Functions. PMID:31781057
Rare Variants in 48 Genes Account for 42% of Cases of Epilepsy With or Without Neurodevelopmental Delay in 246 Pediatric Patients. PMID:31780880
Characterization of genetic subclonal evolution in pancreatic cancer mouse models. PMID:31780749
The mitochondrial genomes of palaeopteran insects and insights into the early insect relationships. PMID:31780743
Germline and somatic mutations of homologous recombination-associated genes in Japanese ovarian cancer patients. PMID:31780705
Highly divergent lineage of narrow-headed vole from the Late Pleistocene Europe. PMID:31780683
547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates. PMID:31779658
Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites. PMID:31777939
Unraveling cis and trans regulatory evolution during cotton domestication. PMID:31776348
GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs. PMID:31776332
Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex. PMID:31776259
Draft Genome Sequence of the Birch Tree Fungal Pathogen Taphrina betulina UCD315. PMID:31776224
Targeted exon sequencing in deceased schizophrenia patients in Denmark. PMID:31773318
From command-line bioinformatics to bioGUI. PMID:31772845
Sequencing and analyses on chloroplast genomes of Tetrataenium candicans and two allies give new insights on structural variants, DNA barcoding and phylogeny in Apiaceae subfamily Apioideae. PMID:31772837
Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles. PMID:31772251
Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network. PMID:31772231
Evolution and Global Transmission of a Multidrug-Resistant, Community-Associated Methicillin-Resistant Staphylococcus aureus Lineage from the Indian Subcontinent. PMID:31772058
Immune receptor repertoires in pediatric and adult acute myeloid leukemia. PMID:31771646
Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores. PMID:31771638
Identification of a Major QTL (qRRs-10.1) That Confers Resistance to Ralstonia solanacearum in Pepper (Capsicum annuum) Using SLAF-BSA and QTL Mapping. PMID:31771239
Assessment of human diploid genome assembly with 10x Linked-Reads data. PMID:31769805
Stalled developmental programs at the root of pediatric brain tumors. PMID:31768071
Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis. PMID:31768029
Sex-dependent dominance maintains migration supergene in rainbow trout. PMID:31768021
Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age. PMID:31767861
JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. PMID:31767855
A chromosome-level genome assembly of the Chinese tupelo Nyssa sinensis. PMID:31767848
Demographic reconstruction from ancient DNA supports rapid extinction of the great auk. PMID:31767056
Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host. PMID:31767028
Comparative Analysis of the YABBY Gene Family of Bienertia sinuspersici, a Single-Cell C4 Plant. PMID:31766767
Genome-Wide Correlation of 36 Agronomic Traits in the 287 Pepper (Capsicum) Accessions Obtained from the SLAF-seq-Based GWAS. PMID:31766117
Clip for studying protein-RNA interactions that regulate virus replication. PMID:31765715
Genome-wide histone modification profiling of inner cell mass and trophectoderm of bovine blastocysts by RAT-ChIP. PMID:31765427
STK-12 acts as a transcriptional brake to control the expression of cellulase-encoding genes in Neurospora crassa. PMID:31765390
Applications and analysis of targeted genomic sequencing in cancer studies. PMID:31762958
An RNA-Binding Protein Secreted by a Bacterial Pathogen Modulates RIG-I Signaling. PMID:31761719
Gcn5-Mediated Histone Acetylation Governs Nucleosome Dynamics in Spermiogenesis. PMID:31761669
Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. PMID:31761532
Mutual alteration of NOD2-associated Blau syndrome and IFNγR1 deficiency. PMID:31760574
TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation. PMID:31759822
Analysis of mRNA processing at whole transcriptome level, transcriptomic profile and genome sequence refinement of Trypanosoma cruzi. PMID:31758058
An epigenetic screening determines BET proteins as targets to suppress self-renewal and tumorigenicity in canine mammary cancer cells. PMID:31758045
Oral microbiome diversity in chimpanzees from Gombe National Park. PMID:31758037
Challenges and Approaches to Genotyping Repetitive DNA. PMID:31757929
A Plasmid-Encoded Putative Glycosyltransferase Is Involved in Hop Tolerance and Beer Spoilage in Lactobacillus brevis. PMID:31757821
Natural Variation in a Dendritic Scaffold Protein Remodels Experience-Dependent Plasticity by Altering Neuropeptide Expression. PMID:31757604
Genomic insights from the first chromosome-scale assemblies of oat (Avena spp.) diploid species. PMID:31757219
Exploratory analysis of transposable elements expression in the C. elegans early embryo. PMID:31757208
STRAIN: an R package for multi-locus sequence typing from whole genome sequencing data. PMID:31757201
Identification and quantitation of clinically relevant microbes in patient samples: Comparison of three k-mer based classifiers for speed, accuracy, and sensitivity. PMID:31756192
Coauthor Country Affiliations in International Collaborative Research Funded by the US National Institutes of Health, 2009 to 2017. PMID:31755947
Evolution of Aspergillus oryzae before and after domestication inferred by large-scale comparative genomic analysis. PMID:31755931
Function-driven single-cell genomics uncovers cellulose-degrading bacteria from the rare biosphere. PMID:31754206
EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation. PMID:31752933
Sequencing of animal viruses: quality data assurance for NGS bioinformatics. PMID:31752912
Multiplex nucleotide editing by high-fidelity Cas9 variants with improved efficiency in rice. PMID:31752697
Are personalities genetically determined? Inferences from subsocial spiders. PMID:31752670
Pre-Harvest Survival and Post-Harvest Chlorine Tolerance of Enterohemorrhagic Escherichia coli on Lettuce. PMID:31752303
Exposure to Dimethyl Selenide (DMSe)-Derived Secondary Organic Aerosol Alters Transcriptomic Profiles in Human Airway Epithelial Cells. PMID:31751125
Human chromosome-specific aneuploidy is influenced by DNA-dependent centromeric features. PMID:31750958
Genomic Analysis of Posterior Fossa Meningioma Demonstrates Frequent AKT1 E17K Mutations in Foramen Magnum Meningiomas. PMID:31750041
Campylobacter jejuni isolated from poultry meat in Brazil: in silico analysis and genomic features of two strains with different phenotypes of antimicrobial susceptibility. PMID:31749118
Evolution of small RNA expression following hybridization and allopolyploidization: insights from Spartina species (Poaceae, Chloridoideae). PMID:31748889
Longitudinal molecular trajectories of diffuse glioma in adults. PMID:31748746
Characterization of antibiotic resistance genes in the species of the rumen microbiota. PMID:31748524
Exome resequencing and GWAS for growth, ecophysiology, and chemical and metabolomic composition of wood of Populus trichocarpa. PMID:31747881
Discovery of actionable genetic alterations with targeted panel sequencing in children with relapsed or refractory solid tumors. PMID:31747416
Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices. PMID:31746740
Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease. PMID:31746734
Dynamic response of RNA editing to temperature in grape by RNA deep sequencing. PMID:31745671
A novel single-base mutation in CaBRI1 confers dwarf phenotype and brassinosteroid accumulation in pepper. PMID:31745640
A heterodimer of evolved designer-recombinases precisely excises a human genomic DNA locus. PMID:31745551
The C. elegans 3' UTRome v2 resource for studying mRNA cleavage and polyadenylation, 3'-UTR biology, and miRNA targeting. PMID:31744903
Analysis of Population Structure and Differentially Selected Regions in Guangxi Native Breeds by Restriction Site Associated with DNA Sequencing. PMID:31744899
Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data. PMID:31744515
In-depth serum virome analysis in patients with acute liver failure with indeterminate etiology. PMID:31741097
Genomic basis of European ash tree resistance to ash dieback fungus. PMID:31740845
The mutational footprints of cancer therapies. PMID:31740835
A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis. PMID:31740783
Widespread long-range cis-regulatory elements in the maize genome. PMID:31740773
CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines. PMID:31739488
High-throughput genotyping of a full voltage-gated sodium channel gene via genomic DNA using target capture sequencing and analytical pipeline MoNaS to discover novel insecticide resistance mutations. PMID:31738756
Genomic analyses provide insights into breed-of-origin effects from purebreds on three-way crossbred pigs. PMID:31737448
Genome-Wide Analysis of Genetic Diversity in Plasmodium falciparum Isolates From China-Myanmar Border. PMID:31737048
Identifying Temporally Regulated Root Nodulation Biomarkers Using Time Series Gene Co-Expression Network Analysis. PMID:31737022
Peptides Derived of Kunitz-Type Serine Protease Inhibitor as Potential Vaccine Against Experimental Schistosomiasis. PMID:31736947
Changes in the Carbon Metabolism of Escherichia coli During the Evolution of Doxycycline Resistance. PMID:31736928
Single-Cell RNA Sequencing of Plant-Associated Bacterial Communities. PMID:31736899
ParameciumDB 2019: integrating genomic data across the genus for functional and evolutionary biology. PMID:31733062
Xenbase: deep integration of GEO & SRA RNA-seq and ChIP-seq data in a model organism database. PMID:31733057
Anaerobic Degradation of Syringic Acid by an Adapted Strain of Rhodopseudomonas palustris. PMID:31732577
Cell-free transcription in Xenopus egg extract. PMID:31732562
Genome-Wide Identification and Characterization of FBA Gene Family in Polyploid Crop Brassica napus. PMID:31731804
Identification of SERPINE1 as a Regulator of Glioblastoma Cell Dispersal with Transcriptome Profiling. PMID:31731490
Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing. PMID:31730858
Ion torrent high throughput mitochondrial genome sequencing (HTMGS). PMID:31730669
WGS based study of the population structure of Salmonella enterica serovar Infantis. PMID:31730461
Identification of Bna.IAA7.C05 as allelic gene for dwarf mutant generated from tissue culture in oilseed rape. PMID:31729952
Maize transposable elements contribute to long non-coding RNAs that are regulatory hubs for abiotic stress response. PMID:31729949
Exogenous ERα Expression in the Mammary Epithelium Decreases Over Time and Does Not Contribute to p53-Deficient Mammary Tumor Formation in Mice. PMID:31729597
RBV: Read balance validator, a tool for prioritising copy number variations in germline conditions. PMID:31729446
The indica nitrate reductase gene OsNR2 allele enhances rice yield potential and nitrogen use efficiency. PMID:31729387
Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice. PMID:31729367
SyntDB: defining orthologues of human long noncoding RNAs across primates. PMID:31728519
Linkage mapping of quantitative trait loci for fiber yield and its related traits in the population derived from cultivated ramie and wild B. nivea var. tenacissima. PMID:31728008
Sperm DNA Methylation Epimutation Biomarkers for Male Infertility and FSH Therapeutic Responsiveness. PMID:31727924
The wax gourd genomes offer insights into the genetic diversity and ancestral cucurbit karyotype. PMID:31727887
Complete Genome Sequences of Two Listeria Phages of the Genus Pecentumvirus. PMID:31727716
Whole Genome Analysis of a Single Scottish Deerhound Dog Family Provides Independent Corroboration That a SGK3 Coding Variant Leads to Hairlessness. PMID:31727632
Evaluating nanopore sequencing data processing pipelines for structural variation identification. PMID:31727126
Clinical and whole-exome sequencing findings in two siblings from Hani ethnic minority with congenital glycosylation disorders. PMID:31727010
Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections. PMID:31725813
A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B-cell Acute Lymphoblastic Leukemia. PMID:31723839
Regional epigenetic variation in asexual snail populations among urban and rural lakes. PMID:31723440
Native internally calibrated chromatin immunoprecipitation for quantitative studies of histone post-translational modifications. PMID:31723301
Comprehensive genome and transcriptome analyses reveal genetic relationship, selection signature, and transcriptome landscape of small-sized Korean native Jeju horse. PMID:31723199
Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis. PMID:31723039
Genome-Wide Mutagenesis of Hepatitis C Virus Reveals Ability of Genome To Overcome Detrimental Mutations. PMID:31723027
Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment. PMID:31722692
High throughput genotyping of structural variations in a complex plant genome using an original Affymetrix® axiom® array. PMID:31722668
MEGARes 2.0: a database for classification of antimicrobial drug, biocide and metal resistance determinants in metagenomic sequence data. PMID:31722416
A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2. PMID:31722198
Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson's Disease. PMID:31722195
Mitogenomic diversity in Sacred Ibis Mummies sheds light on early Egyptian practices. PMID:31721774
Whole exome sequencing identifies a novel SCN1A mutation in genetic (idiopathic) generalized epilepsy and juvenile myoclonic epilepsy subtypes. PMID:31720899
Y-chromosome haplogroups from Hun, Avar and conquering Hungarian period nomadic people of the Carpathian Basin. PMID:31719606
Mitochondrial somatic mutations and the lack of viral genomic variation in recurrent respiratory papillomatosis. PMID:31719597
Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis. PMID:31719182
A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands. PMID:31719178
Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain. PMID:31719113
Analysis of five deep-sequenced trio-genomes of the Peninsular Malaysia Orang Asli and North Borneo populations. PMID:31718558
Intergenomic gene transfer in diploid and allopolyploid Gossypium. PMID:31718541
Genome draft of the Arabidopsis relative Pachycladon cheesemanii reveals novel strategies to tolerate New Zealand's high ultraviolet B radiation environment. PMID:31718535
A Novel Software and Method for the Efficient Development of Polymorphic SSR Loci Based on Transcriptome Data. PMID:31717904
Viruses in the Invasive Hornet Vespa velutina. PMID:31717432
Transgenerational Response to Nitrogen Deprivation in Arabidopsis thaliana. PMID:31717351
The pulmonary virome, bacteriological and histopathological findings in bovine respiratory disease from western Canada. PMID:31715071
Combination of mass spectrometry and DNA sequencing for detection of antibiotic resistance in diagnostic laboratories. PMID:31713118
Reliable variant calling during runtime of Illumina sequencing. PMID:31712740
Phylogenetic surveillance of travel-related Zika virus infections through whole-genome sequencing methods. PMID:31712570
Virtual methylome dissection facilitated by single-cell analyses. PMID:31711526
Transcriptome analysis identifies genes related to the waxy coating on blueberry fruit in two northern-adapted rabbiteye breeding populations. PMID:31711416
Optimizing Phylogenomics with Rapidly Evolving Long Exons: Comparison with Anchored Hybrid Enrichment and Ultraconserved Elements. PMID:31710677
Landscape of Loci and Candidate Genes for Muscle Fatty Acid Composition in Pigs Revealed by Multiple Population Association Analysis. PMID:31708975
Identification of Single Nucleotide Polymorphism in Red Clover (Trifolium pratense L.) Using Targeted Genomic Amplicon Sequencing and RNA-seq. PMID:31708937
Mycoplasma Chromosomal Transfer: A Distributive, Conjugative Process Creating an Infinite Variety of Mosaic Genomes. PMID:31708906
Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration. PMID:31708418
Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet. PMID:31706703
Independent Origin of XY and ZW Sex Determination Mechanisms in Mosquitofish Sister Species. PMID:31704715
Extracellular vesicle cross-talk between pulmonary artery smooth muscle cells and endothelium during excessive TGF-β signalling: implications for PAH vascular remodelling. PMID:31703702
Effects of parental genetic divergence on gene expression patterns in interspecific hybrids of Camellia. PMID:31703692
VARUS: sampling complementary RNA reads from the sequence read archive. PMID:31703556
Heteroplasmy in the complete chicken mitochondrial genome. PMID:31703075
Selective culture enrichment and sequencing of feces to enhance detection of antimicrobial resistance genes in third-generation cephalosporin resistant Enterobacteriaceae. PMID:31703058
Phylogenomics Identifies an Ancestral Burst of Gene Duplications Predating the Diversification of Aphidomorpha. PMID:31702774
Transcriptional dissection of differentially expressed long non-coding RNAs and messenger RNAs reveals the potential molecular mechanism after kidney transplantation. PMID:31700894
Transcriptome sequencing assisted discovery and computational analysis of novel SNPs associated with flowering in Raphanus sativus in-bred lines for marker-assisted backcross breeding. PMID:31700647
Gene characterization and molecular pathway analysis of reverse thermosensitive genic male sterility in eggplant (Solanum melongena L.). PMID:31700645
Defining the impact of exoribonucleases in the shift between exponential and stationary phases. PMID:31700028
TIP60/KAT5 is required for neuronal viability in hippocampal CA1. PMID:31700011
Emergence of the Ug99 lineage of the wheat stem rust pathogen through somatic hybridisation. PMID:31699975
CRUP: a comprehensive framework to predict condition-specific regulatory units. PMID:31699133
The neurogenomic transition from territory establishment to parenting in a territorial female songbird. PMID:31699031
Analysis of pooled genome sequences from Djallonke and Sahelian sheep of Ghana reveals co-localisation of regions of reduced heterozygosity with candidate genes for disease resistance and adaptation to a tropical environment. PMID:31699027
Molecular characterization of carbapenem-resistant Klebsiella pneumoniae isolates with focus on antimicrobial resistance. PMID:31699025
Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion. PMID:31697816
What does mitogenomics tell us about the evolutionary history of the Drosophila buzzatii cluster (repleta group)? PMID:31697700
Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data. PMID:31697689
Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice. PMID:31697676
Follicular T helper cells shape the HCV-specific CD4+ T cell repertoire after virus elimination. PMID:31697649
Plasmodium vivax Malaria Viewed through the Lens of an Eradicated European Strain. PMID:31697387
A beginner's guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing. PMID:31697321
Free circular introns with an unusual branchpoint in neuronal projections. PMID:31697236
Genomic Epidemiology of Major Extraintestinal Pathogenic Escherichia coli Lineages Causing Urinary Tract Infections in Young Women Across Canada. PMID:31696141
Staphylococcus aureus Small Colony Variants (SCVs): News From a Chronic Prosthetic Joint Infection. PMID:31696062
Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis. PMID:31695033
From cytogenetics to cytogenomics: whole-genome sequencing as a first-line test comprehensively captures the diverse spectrum of disease-causing genetic variation underlying intellectual disability. PMID:31694722
rDNA Clusters Make Contact with Genes that Are Involved in Differentiation and Cancer and Change Contacts after Heat Shock Treatment. PMID:31694324
Non-Specific Lipid Transfer Proteins in Triticum kiharae Dorof. et Migush.: Identification, Characterization and Expression Profiling in Response to Pathogens and Resistance Inducers. PMID:31694319
Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. PMID:31693904
Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15. PMID:31693891
Influenza classification from short reads with VAPOR facilitates robust mapping pipelines and zoonotic strain detection for routine surveillance applications. PMID:31693070
A diagnostic ceiling for exome sequencing in cerebellar ataxia and related neurological disorders. PMID:31692161
Alternative splicing of a barley gene results in an excess-tillering and semi-dwarf mutant. PMID:31690990
Three Quantitative Trait Loci Explain More than 60% of Variation for Chill Coma Recovery Time in a Natural Population of Drosophila ananassae. PMID:31690597
Mash Screen: high-throughput sequence containment estimation for genome discovery. PMID:31690338
Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose. PMID:31690329
The mutational landscape of quinolone resistance in Escherichia coli. PMID:31689338
Genome-wide SNP analyses reveal population structure of Portunus pelagicus along Vietnam coastline. PMID:31689298
The Effect of Population Bottleneck Size and Selective Regime on Genetic Diversity and Evolvability in Bacteria. PMID:31688900
A High-Quality Assembly of the Nine-Spined Stickleback (Pungitius pungitius) Genome. PMID:31687752
Whole-genome sequencing of ocular Chlamydia trachomatis isolates from Gadarif State, Sudan. PMID:31685017
Genetic regulation of gene expression and splicing during a 10-year period of human aging. PMID:31684996
Clinical, genetic, and molecular characterization of hyperphosphatasia with mental retardation: a case report and literature review. PMID:31684969
gRNA validation for wheat genome editing with the CRISPR-Cas9 system. PMID:31684940
Assembly, annotation, and comparison of Macrophomina phaseolina isolates from strawberry and other hosts. PMID:31684862
Modulation of flagellar rotation in surface-attached bacteria: A pathway for rapid surface-sensing after flagellar attachment. PMID:31682637
Chromosomal-level reference genome of Chinese peacock butterfly (Papilio bianor) based on third-generation DNA sequencing and Hi-C analysis. PMID:31682256
Use of whole-genome sequencing to identify clusters of Shigella flexneri associated with sexual transmission in men who have sex with men in England: a validation study using linked behavioural data. PMID:31682221
Development of a Genomic Resource and Identification of Nucleotide Diversity of Yellow Perch by RAD Sequencing. PMID:31681426
Mip6 binds directly to the Mex67 UBA domain to maintain low levels of Msn2/4 stress-dependent mRNAs. PMID:31680439
R-Loops Promote Antisense Transcription across the Mammalian Genome. PMID:31679819
Consequences of past climate change and recent human persecution on mitogenomic diversity in the arctic fox. PMID:31679495
Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism. PMID:31677974
Genetic mapping of green curd gene Gr in cauliflower. PMID:31676958
The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes. PMID:31676868
TM3'seq: A Tagmentation-Mediated 3' Sequencing Approach for Improving Scalability of RNAseq Experiments. PMID:31676507
Local Adaptation of Bacterial Symbionts within a Geographic Mosaic of Antibiotic Coevolution. PMID:31676475
Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation during DNA Replication. PMID:31675501
Sharing interoperable workflow provenance: A review of best practices and their practical application in CWLProv. PMID:31675414
Investigation of the genes associated with a male sterility mutant (msm) in Chinese cabbage (Brassica campestris ssp. pekinensis) using RNA-Seq. PMID:31673754
Whole mitochondrial genome sequencing highlights mitochondrial impact in gastric cancer. PMID:31673122
Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population. PMID:31673068
The Personal Genome Project-UK, an open access resource of human multi-omics data. PMID:31672996
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development. PMID:31672993
Draft Genome Sequences of Two Isolates of the Yeast Kazachstania servazzii Recovered from Soil in Ireland. PMID:31672753
Draft Genome Sequence of a Red Basidiomycete Yeast, Symmetrospora coprosmae Strain UCD350, Isolated from Soil in Ireland. PMID:31672752
Complete Genome Sequence of the Nosocomial Pathogen Acinetobacter nosocomialis Strain M2. PMID:31672736
Computational Analysis Concerning the Impact of DNA Accessibility on CRISPR-Cas9 Cleavage Efficiency. PMID:31672284
Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads. PMID:31672156
Metagenomic Analysis of Virioplankton from the Pelagic Zone of Lake Baikal. PMID:31671744
The Many Faces of Gene Regulation in Cancer: A Computational Oncogenomics Outlook. PMID:31671657
The dual benefit of a dominant mutation in Arabidopsis IRON DEFICIENCY TOLERANT1 for iron biofortification and heavy metal phytoremediation. PMID:31671241
Evaluation of protocols for rRNA depletion-based RNA sequencing of nanogram inputs of mammalian total RNA. PMID:31671154
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. PMID:31668803
The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities. PMID:31667520
Genome replication dynamics of a bacteriophage and its satellite reveal strategies for parasitism and viral restriction. PMID:31667508
PVCTools: parallel variation calling tools. PMID:31667383
MOWChIP-seq for low-input and multiplexed profiling of genome-wide histone modifications. PMID:31666743
Massive gene amplification on a recently formed Drosophila Y chromosome. PMID:31666742
Human gut bacteria contain acquired interbacterial defence systems. PMID:31666699
Detection and identification of transgenic events by next generation sequencing combined with enrichment technologies. PMID:31666537
Hash-Based Core Genome Multilocus Sequence Typing for Clostridium difficile. PMID:31666367
Metagenomic Nanopore Sequencing of Influenza Virus Direct from Clinical Respiratory Samples. PMID:31666364
Complete nontuberculous mycobacteria whole genomes using an optimized DNA extraction protocol for long-read sequencing. PMID:31666009
Identification of CFTR variants in Latino patients with cystic fibrosis from the Dominican Republic and Puerto Rico. PMID:31665830
ReMap 2020: a database of regulatory regions from an integrative analysis of Human and Arabidopsis DNA-binding sequencing experiments. PMID:31665499
Assembly and annotation of the mitochondrial minicircle genome of a differentiation-competent strain of Trypanosoma brucei. PMID:31665448
The Mitochondrial Genome of Eleusine indica and Characterization of Gene Content within Poaceae. PMID:31665327
Intratumoral immunoglobulin isotypes predict survival in lung adenocarcinoma subtypes. PMID:31665076
Characterization of genome-wide variations induced by gamma-ray radiation in barley using RNA-Seq. PMID:31664908
Strong selection pressures maintain divergence on genomic islands in Atlantic cod (Gadus morhua L.) populations. PMID:31664896
RACS: rapid analysis of ChIP-Seq data for contig based genomes. PMID:31664892
Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3. PMID:31664039
Genetic polymorphisms in collagen-related genes are associated with pelvic organ prolapse. PMID:31663982
Functional analysis of RPS27 mutations and expression in melanoma. PMID:31663663
An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma. PMID:31662475
An intragenic duplication of TRPS1 leading to abnormal transcripts and causing trichorhinophalangeal syndrome type I. PMID:31662300
Virus evolution in Wolbachia-infected Drosophila. PMID:31662085
Sorghum MSD3 Encodes an ω-3 Fatty Acid Desaturase that Increases Grain Number by Reducing Jasmonic Acid Levels. PMID:31661847
RaGOO: fast and accurate reference-guided scaffolding of draft genomes. PMID:31661016
Genome landscapes of rectal cancer before and after preoperative chemoradiotherapy. PMID:31660073
A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers. PMID:31659164
Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen Pseudomonas aeruginosa. PMID:31658946
Virus Adaptation and Selection Following Challenge of Animals Vaccinated against Classical Swine Fever Virus. PMID:31658773
Dysregulation of Placental Functions and Immune Pathways in Complete Hydatidiform Moles. PMID:31658584
Measurable residual disease monitoring for patients with acute myeloid leukemia following hematopoietic cell transplantation using error corrected hybrid capture next generation sequencing. PMID:31658273
The quorum sensing transcription factor AphA directly regulates natural competence in Vibrio cholerae. PMID:31658256
Single-nucleotide polymorphism markers within MVA and MEP pathways among Hevea brasiliensis clones through transcriptomic analysis. PMID:31656726
Dynamic gene expression changes in response to micronutrient, macronutrient, and multiple stress exposures in soybean. PMID:31655948
Environmental transcriptomes of invasive dreissena, a model species in ecotoxicology and invasion biology. PMID:31653851
Cell type-specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells. PMID:31653691
The Fate of Deleterious Variants in a Barley Genomic Prediction Population. PMID:31653677
Environmental Conditions May Shape the Patterns of Genomic Variations in Leishmania panamensis. PMID:31652919
Paralog buffering contributes to the variable essentiality of genes in cancer cell lines. PMID:31652272
Uncovering and characterizing splice variants associated with survival in lung cancer patients. PMID:31652257
The Amount of RNA Editing Sites in Liverwort Organellar Genes Is Correlated with GC Content and Nuclear PPR Protein Diversity. PMID:31651960
Whole genome analysis of Black Bengal goat from Savar Goat Farm, Bangladesh. PMID:31651366
Comment on 'Single nucleus sequencing reveals evidence of inter-nucleus recombination in arbuscular mycorrhizal fungi'. PMID:31650958
Deep Small RNA Sequencing of BRAF V600E Mutated Papillary Thyroid Carcinoma With Lymph Node Metastasis. PMID:31649724
Novel Informatic Tools to Support Functional Annotation of the Durum Wheat Genome. PMID:31649706
Whole-Genome Resequencing of Seven Eggplant (Solanum melongena) and One Wild Relative (S. incanum) Accessions Provides New Insights and Breeding Tools for Eggplant Enhancement. PMID:31649694
Sleep Deprivation Alters the Pituitary Stress Transcriptome in Male and Female Mice. PMID:31649619
Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis. PMID:31649238
RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-sequencing. PMID:31649132
AP2/ERF Transcription Factors Integrate Age and Wound Signals for Root Regeneration. PMID:31649122
Molecular profiling of stem cell-like female germ line cells in Drosophila delineates networks important for stemness and differentiation. PMID:31649115
Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets. PMID:31648313
The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus. PMID:31647415
Rare variants contribute disproportionately to quantitative trait variation in yeast. PMID:31647408
Whole-genome resequencing of Cucurbita pepo morphotypes to discover genomic variants associated with morphology and horticulturally valuable traits. PMID:31645952
Metabolic regulation of gene expression by histone lactylation. PMID:31645732
Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination. PMID:31644912
Cutaneous Immune Cell-Microbiota Interactions Are Controlled by Epidermal JunB/AP-1. PMID:31644908
Show me your secret(ed) weapons: a multifaceted approach reveals a wide arsenal of type III-secreted effectors in the cucurbit pathogenic bacterium Acidovorax citrulli and novel effectors in the Acidovorax genus. PMID:31643123
SilkDB 3.0: visualizing and exploring multiple levels of data for silkworm. PMID:31642484
Genomic Basis of Convergent Island Phenotypes in Boa Constrictors. PMID:31642474
Genomic analysis reveals rich genetic variation and potential targets of selection during domestication of castor bean from perennial woody tree to annual semi-woody crop. PMID:31641699
Exploring a Pool-seq-only approach for gaining population genomic insights in nonmodel species. PMID:31641485
The draft genome of Actinia tenebrosa reveals insights into toxin evolution. PMID:31641475
Extensive genetic differentiation between recently evolved sympatric Arctic charr morphs. PMID:31641448
eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA. PMID:31641155
Chromosome-level genome assembly of golden pompano (Trachinotus ovatus) in the family Carangidae. PMID:31641137
The global diversity of Haemonchus contortus is shaped by human intervention and climate. PMID:31641125
The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. PMID:31640799
Impact of a single round of mass drug administration with azithromycin on active trachoma and ocular Chlamydia trachomatis prevalence and circulating strains in The Gambia and Senegal. PMID:31640755
NARD: whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants. PMID:31640730
Altered lentiviral infection dynamics follow genetic rescue of the Florida panther. PMID:31640509
Molecular Characterization of Leishmania RNA virus 2 in Leishmania major from Uzbekistan. PMID:31640177
Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo. PMID:31639368
Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off. PMID:31638576
Transposition of a non-autonomous DNA transposon in the gene coding for a bHLH transcription factor results in a white bulb color of onions (Allium cepa L.). PMID:31637460
Additional Evidence for DDB2 T338M as a Genetic Risk Factor for Ocular Squamous Cell Carcinoma in Horses. PMID:31637255
Compensatory trans-regulatory alleles minimizing variation in TDH3 expression are common within Saccharomyces cerevisiae. PMID:31636938
A transcriptional response of Clostridium beijerinckii NRRL B-598 to a butanol shock. PMID:31636702
Denoising of Aligned Genomic Data. PMID:31636330
Comparative Study of Gut Microbiota in Wild and Captive Giant Pandas (Ailuropoda melanoleuca). PMID:31635158
A Genome-Centric Approach Reveals a Novel Glycosyltransferase from the GA A07 Strain of Bacillus thuringiensis Responsible for Catalyzing 15-O-Glycosylation of Ganoderic Acid A. PMID:31635144
Cis-regulatory basis of sister cell type divergence in the vertebrate retina. PMID:31633482
Spinocerebellar Ataxia type 29 in a family of Māori descent. PMID:31632679
Associations between genomic ancestry, genome size and capitula morphology in the invasive meadow knapweed hybrid complex (Centaurea × moncktonii) in eastern North America. PMID:31632628
Evaluating Population Genetic Structure and Demographic History of Quercus spinosa (Fagaceae) Based on Specific Length Amplified Fragment Sequencing. PMID:31632447
Transcriptome Analysis Reveals That Alfalfa Promotes Rumen Development Through Enhanced Metabolic Processes and Calcium Transduction in Hu Lambs. PMID:31632445
An Early mtUPR: Redistribution of the Nuclear Transcription Factor Rox1 to Mitochondria Protects against Intramitochondrial Proteotoxic Aggregates. PMID:31630969
The Dynamic Chromatin Architecture of the Regenerating Liver. PMID:31629814
CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples. PMID:31628304
Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. PMID:31626773
Local adaptation drives the diversification of effectors in the fungal wheat pathogen Parastagonospora nodorum in the United States. PMID:31626626
An EMS-induced mutation in a tetratricopeptide repeat-like superfamily protein gene (Ghir_A12G008870) on chromosome A12 is responsible for the liy short fiber phenotype in cotton. PMID:31624873
Mutations in sorghum SBEIIb and SSIIa affect alkali spreading value, starch composition, thermal properties and flour viscosity. PMID:31624872
MBKbase for rice: an integrated omics knowledgebase for molecular breeding in rice. PMID:31624841
Historical museum collections clarify the evolutionary history of cryptic species radiation in the world's largest amphibians. PMID:31624538
Extremophilic nitrite-oxidizing Chloroflexi from Yellowstone hot springs. PMID:31624340
The vernalisation regulator FLOWERING LOCUS C is differentially expressed in biennial and annual Brassica napus. PMID:31624282
Genome Sequence of an Unknown Subtype of Hepatitis C Virus Genotype 6: Another Piece for the Taxonomic Puzzle. PMID:31624172
Complete Genome Sequence of a Virulent African Swine Fever Virus from a Domestic Pig in Ukraine. PMID:31624164
Draft Genome Sequences of 12 Monophasic Salmonella enterica subsp. enterica Serotype Typhimurium 1,4,[5],12:i:- Strains Isolated from Wild Griffon Vultures in Eastern Spain. PMID:31624159
Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. PMID:31624127
Global Transcriptional Response of Three Highly Acid-Tolerant Field Strains of Listeria monocytogenes to HCl Stress. PMID:31623206
Factors Affecting Targeted Sequencing of 353 Nuclear Genes From Herbarium Specimens Spanning the Diversity of Angiosperms. PMID:31620145
Nucleotide resolution profiling of m7G tRNA modification by TRAC-Seq. PMID:31619810
Methylation content sensitive enzyme ddRAD (MCSeEd): a reference-free, whole genome profiling system to address cytosine/adenine methylation changes. PMID:31619715
A genome-wide assessment of the ancestral neural crest gene regulatory network. PMID:31619682
Identification of Key Genes for the Precise Classification between Solenopsis invicta and S. geminata Facilitating the Quarantine Process. PMID:31618982
Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes. PMID:31618917
Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51. PMID:31618627
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells. PMID:31616795
The feedback between selection and demography shapes genomic diversity during coevolution. PMID:31616788
New Recurrent Structural Aberrations in the Genome of Chronic Lymphocytic Leukemia Based on Exome-Sequencing Data. PMID:31616467
Hidden Rice Diversity in the Guianas. PMID:31616452
Genome-wide association mapping of date palm fruit traits. PMID:31615981
Combination of Proteogenomics with Peptide De Novo Sequencing Identifies New Genes and Hidden Posttranscriptional Modifications. PMID:31615963
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion. PMID:31615920
Construction of genetic linkage map and identification of a novel major locus for resistance to pine wood nematode in Japanese black pine (Pinus thunbergii). PMID:31615405
dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA. PMID:31615058
Transcriptome-Based SNP Discovery and Validation in the Hybrid Zone of the Neotropical Annual Fish Genus Austrolebias. PMID:31614537
17β-Estradiol Activates HSF1 via MAPK Signaling in ERα-Positive Breast Cancer Cells. PMID:31614463
Helicobacter pylori Stress-Response: Definition of the HrcA Regulon. PMID:31614448
The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. PMID:31612858
Rare human mitochondrial HV lineages spread from the Near East and Caucasus during post-LGM and Neolithic expansions. PMID:31611588
Capturing the Resistome: a Targeted Capture Method To Reveal Antibiotic Resistance Determinants in Metagenomes. PMID:31611361
A Highly Contiguous Reference Genome for Northern Bobwhite (Colinus virginianus). PMID:31611345
Parsing the synonymous mutations in the maize genome: isoaccepting mutations are more advantageous in regions with codon co-occurrence bias. PMID:31610786
Ethylene-responsive factor 4 is associated with the desirable rind hardness trait conferring cracking resistance in fresh fruits of watermelon. PMID:31610078
Supporting evidence for a human reservoir of invasive non-Typhoidal Salmonella from household samples in Burkina Faso. PMID:31609964
Transcriptome dynamics of the Myxococcus xanthus multicellular developmental program. PMID:31609203
Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures. PMID:31608115
Elimination of Reference Mapping Bias Reveals Robust Immune Related Allele-Specific Expression in Crossbred Sheep. PMID:31608110
Evaluation of the Performance of AmpliSeq and SureSelect Exome Sequencing Libraries for Ion Proton. PMID:31608108
Genomic Characterization of the Periwinkle Leaf Yellowing (PLY) Phytoplasmas in Taiwan. PMID:31608032
Integrative Analysis of miRNA and mRNA Expression Profiles Associated With Human Atrial Aging. PMID:31607954
The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. PMID:31607563
The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations. PMID:31607556
The piRNA Response to Retroviral Invasion of the Koala Genome. PMID:31607510
Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice. PMID:31606247
Genomic analysis of the four ecologically distinct cactus host populations of Drosophila mojavensis. PMID:31606030
The allotetraploid origin and asymmetrical genome evolution of the common carp Cyprinus carpio. PMID:31604932
Longshot enables accurate variant calling in diploid genomes from single-molecule long read sequencing. PMID:31604920
The de Novo Reference Genome and Transcriptome Assemblies of the Wild Tomato Species Solanum chilense Highlights Birth and Death of NLR Genes Between Tomato Species. PMID:31604826
Lanthanide-Dependent Methylotrophs of the Family Beijerinckiaceae: Physiological and Genomic Insights. PMID:31604774
Evolutionary flexibility in flooding response circuitry in angiosperms. PMID:31604238
A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs. PMID:31603892
Global analysis of protein synthesis in Flavobacterium johnsoniae reveals the use of Kozak-like sequences in diverse bacteria. PMID:31602466
Detection of spacer precursors formed in vivo during primed CRISPR adaptation. PMID:31601800
Complete Genome Sequences and Transmission Electron Micrographs of Listeria Phages of the Genus Homburgvirus. PMID:31601662
Eleven High-Quality Reference Genome Sequences and 360 Draft Assemblies of Shiga Toxin-Producing Escherichia coli Isolates from Human, Food, Animal, and Environmental Sources in Canada. PMID:31601655
Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling. PMID:31601616
Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers. PMID:31601552
Re-evaluation of a Tn5::gacA mutant of Pseudomonas syringae pv. tomato DC3000 uncovers roles for uvrC and anmK in promoting virulence. PMID:31600319
Evidence of Neutral Evolution of Mitochondrial DNA in Human Hepatocellular Carcinoma. PMID:31599941
Evaluating Chromatin Accessibility Differences Across Multiple Primate Species Using a Joint Modeling Approach. PMID:31599933
CTCF confers local nucleosome resiliency after DNA replication and during mitosis. PMID:31599722
Malignant ascites-derived organoid (MADO) cultures for gastric cancer in vitro modelling and drug screening. PMID:31598791
Inherited Chromosomally Integrated Human Herpesvirus 6 Demonstrates Tissue-Specific RNA Expression In Vivo That Correlates with an Increased Antibody Immune Response. PMID:31597766
Fertility of Pedicellate Spikelets in Sorghum Is Controlled by a Jasmonic Acid Regulatory Module. PMID:31597271
The U1 spliceosomal RNA is recurrently mutated in multiple cancers. PMID:31597163
Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships. PMID:31597106
Whole genome resequencing of watermelons to identify single nucleotide polymorphisms related to flesh color and lycopene content. PMID:31596903
miRWoods: Enhanced precursor detection and stacked random forests for the sensitive detection of microRNAs. PMID:31596843
Mapping of Multiple Complementary Sex Determination Loci in a Parasitoid Wasp. PMID:31596478
Human virome in nasopharynx and tracheal secretion samples. PMID:31596309
Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer. PMID:31594934
Variation in genome content and predatory phenotypes between Bdellovibrio sp. NC01 isolated from soil and B. bacteriovorus type strain HD100. PMID:31592759
The Grass Carp Genomic Visualization Database (GCGVD): an informational platform for genome biology of grass carp. PMID:31592084
Improved characterisation of MRSA transmission using within-host bacterial sequence diversity. PMID:31591959
Genome-wide germline correlates of the epigenetic landscape of prostate cancer. PMID:31591588
Ikaros prevents autoimmunity by controlling anergy and Toll-like receptor signaling in B cells. PMID:31591571
High GILT Expression and an Active and Intact MHC Class II Antigen Presentation Pathway Are Associated with Improved Survival in Melanoma. PMID:31591149
Sequence-based epidemiology of an OXA-48 plasmid during a hospital outbreak. PMID:31591122
Reduced Virulence of an Introduced Forest Pathogen over 50 Years. PMID:31590374
Continued Adaptation of C4 Photosynthesis After an Initial Burst of Changes in the Andropogoneae Grasses. PMID:31589325
ReQTL: identifying correlations between expressed SNVs and gene expression using RNA-sequencing data. PMID:31589315
Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State. PMID:31588023
Single cell ecogenomics reveals mating types of individual cells and ssDNA viral infections in the smallest photosynthetic eukaryotes. PMID:31587637
Characterization of a Saccharum spontaneum with a basic chromosome number of x = 10 provides new insights on genome evolution in genus Saccharum. PMID:31587087
Ribosome assembly defects subvert initiation Factor3 mediated scrutiny of bona fide start signal. PMID:31586395
Chromatin Assembly Factor 1 (CAF-1) facilitates the establishment of facultative heterochromatin during pluripotency exit. PMID:31586391
Genetic modification of primary human B cells to model high-grade lymphoma. PMID:31586074
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease. PMID:31586071
A new PacBio genome sequence of an Australian Pyrenophora tritici-repentis race 1 isolate. PMID:31585535
Diagnostic Utility of Next-Generation Sequencing for Disorders of Somatic Mosaicism: A Five-Year Cumulative Cohort. PMID:31585106
Genomic Decoding of Neuronal Depolarization by Stimulus-Specific NPAS4 Heterodimers. PMID:31585079
Meltos: multi-sample tumor phylogeny reconstruction for structural variants. PMID:31584621
SCSsim: an integrated tool for simulating single-cell genome sequencing data. PMID:31584615
Unique and assay specific features of NOMe-, ATAC- and DNase I-seq data. PMID:31584093
Coordinated removal of repressive epigenetic modifications during induced reversal of cell identity. PMID:31583744
Functional annotation of mulberry (Morus spp.) transcriptome, differential expression of genes related to growth and identification of putative genic SSRs, SNPs and InDels. PMID:31583573
Selection of miRNA reference genes for plant defence studies in rice (Oryza sativa). PMID:31583464
Divergent evolutionary trajectories following speciation in two ectoparasitic honey bee mites. PMID:31583288
Draft genome sequence of fastidious pathogen Ceratobasidium theobromae, which causes vascular-streak dieback in Theobroma cacao. PMID:31583107
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming. PMID:31582858
Coastal Ocean Metagenomes and Curated Metagenome-Assembled Genomes from Marsh Landing, Sapelo Island (Georgia, USA). PMID:31582460
Whole-Genome Sequencing of a Mycobacterium orygis Strain Isolated from Cattle in Chennai, India. PMID:31582446
Complete Genome Sequence of Multidrug-Resistant Salmonella enterica Serovar I 4,[5],12:i:- 2015 U.S. Pork Outbreak Isolate USDA15WA-1. PMID:31582436
Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling. PMID:31582430
Unraveling the Heterogeneous Mutational Signature of Spontaneously Developing Tumors in MLH1-/- Mice. PMID:31581674
Integrating GWAS and Gene Expression Analysis Identifies Candidate Genes for Root Morphology Traits in Maize at the Seedling Stage. PMID:31581635
Additional Layer of Regulation via Convergent Gene Orientation in Yeasts. PMID:31580446
Dissecting the Effects of Selection and Mutation on Genetic Diversity in Three Wood White (Leptidea) Butterfly Species. PMID:31580421
T-lex3: an accurate tool to genotype and estimate population frequencies of transposable elements using the latest short-read whole genome sequencing data. PMID:31580402
Molecular evolution of the meiotic recombination pathway in mammals. PMID:31579931
Oncogenic Rag GTPase signaling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR. PMID:31579886
A draft genome and transcriptome of common milkweed (Asclepias syriaca) as resources for evolutionary, ecological, and molecular studies in milkweeds and Apocynaceae. PMID:31579586
The sugarcane mitochondrial genome: assembly, phylogenetics and transcriptomics. PMID:31579570
Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors. PMID:31578350
Reviving rare chicken breeds using genetically engineered sterility in surrogate host birds. PMID:31575742
Pedigree-based estimation of human mobile element retrotransposition rates. PMID:31575651
Genome Assemblies of Two Rare Opportunistic Yeast Pathogens: Diutina rugosa (syn. Candida rugosa) and Trichomonascus ciferrii (syn. Candida ciferrii). PMID:31575637
Draft genome sequence of Solanum aethiopicum provides insights into disease resistance, drought tolerance, and the evolution of the genome. PMID:31574156
Putative Mitochondrial Sex Determination in the Bivalvia: Insights From a Hybrid Transcriptome Assembly in Freshwater Mussels. PMID:31572447
Weighted Gene Co-Expression Analyses Point to Long Non-Coding RNA Hub Genes at Different Schistosoma mansoni Life-Cycle Stages. PMID:31572441
Functional Characterization of a Global Virulence Regulator Hfq and Identification of Hfq-Dependent sRNAs in the Plant Pathogen Pantoea ananatis. PMID:31572315
Distinct patterns of natural selection determine sub-population structure in the fire blight pathogen, Erwinia amylovora. PMID:31570749
Multiple modes of convergent adaptation in the spread of glyphosate-resistant Amaranthus tuberculatus. PMID:31570613
Knockout of juvenile hormone receptor, Methoprene-tolerant, induces black larval phenotype in the yellow fever mosquito, Aedes aegypti. PMID:31570611
Contemporary evolution of maize landraces and their wild relatives influenced by gene flow with modern maize varieties. PMID:31570572
Sufficiency analysis of estrogen responsive enhancers using synthetic activators. PMID:31570515
Bacterial IAA-Delivery into Medicago Root Nodules Triggers a Balanced Stimulation of C and N Metabolism Leading to a Biomass Increase. PMID:31569530
Telescope: Characterization of the retrotranscriptome by accurate estimation of transposable element expression. PMID:31568525
Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation. PMID:31568516
Identifying Crohn's disease signal from variome analysis. PMID:31564248
Identification of a polymorphism within the Rosa multiflora muRdr1A gene linked to resistance to multiple races of Diplocarpon rosae W. in tetraploid garden roses (Rosa × hybrida). PMID:31563968
FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis. PMID:31562313
Association Mapping Between Candidate Gene SNP and Production and Oil Quality Traits in Interspecific Oil Palm Hybrids. PMID:31561627
Genome-Wide Analysis of Allele-Specific Expression Patterns in Seventeen Tissues of Korean Cattle (Hanwoo). PMID:31561539
Discovery of Novel Sequences in 1,000 Swedish Genomes. PMID:31560401
RNAseq analysis reveals drought-responsive molecular pathways with candidate genes and putative molecular markers in root tissue of wheat. PMID:31558740
Genome-wide association study overcomes the genome complexity in autohexaploid chrysanthemum and tags SNP markers onto the flower color genes. PMID:31558738
Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast. PMID:31558720
Genome Sequence of Lactobacillus fermentum 47-7, a Good In Vitro Probiotic Strain Isolated from a Healthy Thai Infant. PMID:31558638
Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary. PMID:31558581
Corytophanids Replaced the Pleurodont XY System with a New Pair of XY Chromosomes. PMID:31557287
Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions. PMID:31556488
Paralog dependency indirectly affects the robustness of human cells. PMID:31556487
Role of bulge epidermal stem cells and TSLP signaling in psoriasis. PMID:31556482
A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus. PMID:31554834
BORDER proteins protect expression of neighboring genes by promoting 3' Pol II pausing in plants. PMID:31554790
Genome Improvement and Genetic Map Construction for Aethionema arabicum, the First Divergent Branch in the Brassicaceae Family. PMID:31554715
Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation. PMID:31554518
Ketamine Increases Proliferation of Human iPSC-Derived Neuronal Progenitor Cells via Insulin-Like Growth Factor 2 and Independent of the NMDA Receptor. PMID:31554266
Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. PMID:31553912
Genomic analyses reveal an absence of contemporary introgressive admixture between fin whales and blue whales, despite known hybrids. PMID:31553763
Host transcriptome and microbiome interaction modulates physiology of full-sibs broilers with divergent feed conversion ratio. PMID:31552140
Machine Learning Classifiers for Endometriosis Using Transcriptomics and Methylomics Data. PMID:31552087
Pleurotus eryngii Genomes Reveal Evolution and Adaptation to the Gobi Desert Environment. PMID:31551962
Population Genomics of an Obligately Halophilic Basidiomycete Wallemia ichthyophaga. PMID:31551960
Revealing the Virulence Potential of Clinical and Environmental Aspergillus fumigatus Isolates Using Whole-Genome Sequencing. PMID:31551947
Soil Metatranscriptomes Under Long-Term Experimental Warming and Drying: Fungi Allocate Resources to Cell Metabolic Maintenance Rather Than Decay. PMID:31551941
Single-cell transcriptomic profiling of the aging mouse brain. PMID:31551601
A perturbed gene network containing PI3K-AKT, RAS-ERK and WNT-β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity. PMID:31551593
Olfactory receptor gene abundance in invasive breast carcinoma. PMID:31551495
Reference gene and small RNA data from multiple tissues of Davidia involucrata Baill. PMID:31551451
CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder. PMID:31551426
Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma. PMID:31551362
The Parauncinula polyspora Draft Genome Provides Insights into Patterns of Gene Erosion and Genome Expansion in Powdery Mildew Fungi. PMID:31551331
Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation. PMID:31549960
In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma. PMID:31548728
Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases. PMID:31548716
Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA. PMID:31548705
Regional epigenetic differentiation of the Z Chromosome between sexes in a female heterogametic system. PMID:31548356
Environmentally induced plasticity of programmed DNA elimination boosts somatic variability in Paramecium tetraurelia. PMID:31548355
Worldwide relationships in the fern genus Pteridium (bracken) based on nuclear genome markers. PMID:31545874
Variant analysis pipeline for accurate detection of genomic variants from transcriptome sequencing data. PMID:31545812
Next-generation forward genetic screens: using simulated data to improve the design of mapping-by-sequencing experiments in Arabidopsis. PMID:31544937
Phage Predation Shapes the Population Structure of Shiga-Toxigenic Escherichia coli O157:H7 in the UK: An Evolutionary Perspective. PMID:31543896
Genetic Diversity Linked to Haplotype Variation in the World Core Collection of Trifolium subterraneum for Boron Toxicity Tolerance Provides Valuable Markers for Pasture Breeding. PMID:31543883
Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons. PMID:31543366
Genomic epidemiology of Iranian Bordetella pertussis: 50 years after the implementation of whole cell vaccine. PMID:31543006
ImmGen report: sexual dimorphism in the immune system transcriptome. PMID:31541153
Genetic lines respond uniquely within the chicken thymic transcriptome to acute heat stress and low dose lipopolysaccharide. PMID:31541148
Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross. PMID:31541097
Genome-wide recombination map construction from single individuals using linked-read sequencing. PMID:31541091
Linked-read sequencing of gametes allows efficient genome-wide analysis of meiotic recombination. PMID:31541084
TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. PMID:31541082
Escherichia coli Clonobiome: Assessing the Strain Diversity in Feces and Urine by Deep Amplicon Sequencing. PMID:31540992
Phased Diploid Genome Assemblies for Three Strains of Candida albicans from Oak Trees. PMID:31540974
A Transcriptome Analysis Identifies Biological Pathways and Candidate Genes for Feed Efficiency in DLY Pigs. PMID:31540540
Bulked segregant analysis RNA-seq (BSR-Seq) validated a stem resistance locus in Aegilops umbellulata, a wild relative of wheat. PMID:31539379
Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans. PMID:31538139
Segregation and potential functional impact of a rare stop-gain PABPC4L variant in familial atypical Parkinsonism. PMID:31537871
Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. PMID:31537794
An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation. PMID:31537784
NGS analysis in Marfan syndrome spectrum: Combination of rare and common genetic variants to improve genotype-phenotype correlation analysis. PMID:31536524
Whole genome sequencing data and analysis of a rifampicin-resistant Mycobacterium tuberculosis strain SBH162 from Sabah, Malaysia. PMID:31534995
Little evidence of adaptation potential to ocean acidification in sea urchins living in "Future Ocean" conditions at a CO2 vent. PMID:31534709
Last exit before the brink: Conservation genomics of the Cambodian population of the critically endangered southern river terrapin. PMID:31534671
ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation. PMID:31534165
Rapid Detection of Genetic Engineering, Structural Variation, and Antimicrobial Resistance Markers in Bacterial Biothreat Pathogens by Nanopore Sequencing. PMID:31534162
Admixture between old lineages facilitated contemporary ecological speciation in Lake Constance stickleback. PMID:31534121
Transcriptional alterations in glioma result primarily from DNA methylation-independent mechanisms. PMID:31533980
Widespread cis-regulatory convergence between the extinct Tasmanian tiger and gray wolf. PMID:31533979
Identification and characterization of NF1 and non-NF1 congenital pseudarthrosis of the tibia based on germline NF1 variants: genetic and clinical analysis of 75 patients. PMID:31533797
Distinct impact of antibiotics on the gut microbiome and resistome: a longitudinal multicenter cohort study. PMID:31533707
Haplotype-resolved genomes of geminivirus-resistant and geminivirus-susceptible African cassava cultivars. PMID:31533702
Α de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous female calf with generalized hypohidrotic ectodermal dysplasia. PMID:31533624
Allele-Specific Expression of CD4+ T Cells in Response to Marek's Disease Virus Infection. PMID:31533276
Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells. PMID:31533047
Polymer Modeling Predicts Chromosome Reorganization in Senescence. PMID:31533042
Inverted translational control of eukaryotic gene expression by ribosome collisions. PMID:31532761
FOXA2 controls the cis-regulatory networks of pancreatic cancer cells in a differentiation grade-specific manner. PMID:31531882
Hibernation induces widespread transcriptional remodeling in metabolic tissues of the grizzly bear. PMID:31531397
Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit. PMID:31531339
A chromosome-level genome assembly of Cydia pomonella provides insights into chemical ecology and insecticide resistance. PMID:31530873
Fluctuating fortunes: genomes and habitat reconstructions reveal global climate-mediated changes in bats' genetic diversity. PMID:31530139
The Genome of the Endangered Dryas Monkey Provides New Insights into the Evolutionary History of the Vervets. PMID:31529046
Genetics of Adaptation of the Ascomycetous Fungus Podospora anserina to Submerged Cultivation. PMID:31529025
Epigenetic transgenerational inheritance of testis pathology and Sertoli cell epimutations: generational origins of male infertility. PMID:31528361
Bat influenza viruses transmit among bats but are poorly adapted to non-bat species. PMID:31527796
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma. PMID:31527657
An Ultra High-Density Arabidopsis thaliana Crossover Map That Refines the Influences of Structural Variation and Epigenetic Features. PMID:31527048
Antimicrobial susceptibility and molecular characterisation using whole-genome sequencing of Clostridioides difficile collected in 82 hospitals in Japan between 2014 and 2016. PMID:31527041
Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients. PMID:31526447
DNA Methylome and Transcriptome Alterations in High Glucose-Induced Diabetic Nephropathy Cellular Model and Identification of Novel Targets for Treatment by Tanshinone IIA. PMID:31525975
Dosage regulation, and variation in gene expression and copy number of human Y chromosome ampliconic genes. PMID:31525193
Ploidy- and Purity-Adjusted Allele-Specific DNA Analysis Using CLONETv2. PMID:31524989
Dynamic turnover of centromeres drives karyotype evolution in Drosophila. PMID:31524597
SLC1A3 contributes to L-asparaginase resistance in solid tumors. PMID:31523835
Genome-resolved insights into a novel Spiroplasma symbiont of the Wheat Stem Sawfly (Cephus cinctus). PMID:31523509
A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells. PMID:31522989
RNA Interactions Are Essential for CTCF-Mediated Genome Organization. PMID:31522988
Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. PMID:31522987
UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. PMID:31522890
Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms. PMID:31521200
Population-wide copy number variation calling using variant call format files from 6,898 individuals. PMID:31520489
A small gene sequencing panel realises a high diagnostic rate in patients with congenital nystagmus following basic phenotyping. PMID:31519934
Lhcx proteins provide photoprotection via thermal dissipation of absorbed light in the diatom Phaeodactylum tricornutum. PMID:31519883
Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes. PMID:31519879
Comparison and Characterization of Mutations Induced by Gamma-Ray and Carbon-Ion Irradiation in Rice (Oryza sativa L.) Using Whole-Genome Resequencing. PMID:31519747
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability. PMID:31519522
Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation. PMID:31519520
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma. PMID:31519498
The Draft Genome of Kochia scoparia and the Mechanism of Glyphosate Resistance via Transposon-Mediated EPSPS Tandem Gene Duplication. PMID:31518388
Exploratory analysis of covariation of microbiota-derived vitamin K and cognition in older adults. PMID:31518386
Detection of de novo genetic variants in Mayer-Rokitansky-Küster-Hauser syndrome by whole genome sequencing. PMID:31517310
The chloroplast and mitochondrial C-to-U RNA editing in Arabidopsis thaliana shows signals of adaptation. PMID:31517178
The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation. PMID:31516833
Combining morphological and genomic evidence to resolve species diversity and study speciation processes of the Pallenopsis patagonica (Pycnogonida) species complex. PMID:31516540
Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes. PMID:31515279
A Deep-Sequencing Workflow for the Fast and Efficient Generation of High-Quality African Swine Fever Virus Whole-Genome Sequences. PMID:31514438
Transcriptome divergence during leaf development in two contrasting switchgrass (Panicum virgatum L.) cultivars. PMID:31513611
Informal genomic surveillance of regional distribution of Salmonella Typhi genotypes and antimicrobial resistance via returning travellers. PMID:31513580
Integrating transcriptomic network reconstruction and eQTL analyses reveals mechanistic connections between genomic architecture and Brassica rapa development. PMID:31513571
Disappearance of Icelandic Walruses Coincided with Norse Settlement. PMID:31513267
Genome-wide analysis and functional prediction of the estrogen-regulated transcriptional response in the mouse uterus†. PMID:31511857
Core set construction and association analysis of Pinus massoniana from Guangdong province in southern China using SLAF-seq. PMID:31511632
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes. PMID:31511524
Spontaneous whole-genome duplication restores fertility in interspecific hybrids. PMID:31511504
Genomic Variation among Strains of Crithidia bombi and C. expoeki. PMID:31511368
Large scale microbiome profiling in the cloud. PMID:31510682
Predicting gene expression in the human malaria parasite Plasmodium falciparum using histone modification, nucleosome positioning, and 3D localization features. PMID:31509524
Shifts in the Human Gut Microbiota Structure Caused by Quadruple Helicobacter pylori Eradication Therapy. PMID:31507546
Heteroplasmy concordance between mitochondrial DNA and RNA. PMID:31506522
Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade. PMID:31506389
Programmed Chromosome Deletion in the Ciliate Oxytricha trifallax. PMID:31506317
Age-related DNA hydroxymethylation is enriched for gene expression and immune system processes in human peripheral blood. PMID:31506003
μLAS technology for DNA isolation coupled to Cas9-assisted targeting for sequencing and assembly of a 30 kb region in plant genome. PMID:31505675
Polymorphism Data Assist Estimation of the Nonsynonymous over Synonymous Fixation Rate Ratio ω for Closely Related Species. PMID:31504782
Programmed genome rearrangements in Oxytricha produce transcriptionally active extrachromosomal circular DNA. PMID:31504770
Enrichment of ovine gonadotropes via adenovirus gene targeting enhances assessment of transcriptional changes in response to estradiol-17 beta†. PMID:31504222
Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API. PMID:31504201
Whole-Genome Sequencing of Yeast Cells. PMID:31503417
Analysis of genome-wide SNPs based on 2b-RAD sequencing of pooled samples reveals signature of selection in different populations of Haemonchus contortus. PMID:31502575
Detection of Microsatellite Instability Biomarkers via Next-Generation Sequencing. PMID:31502149
Assessment of kinship detection using RNA-seq data. PMID:31501877
Adaptive Radiation of the Flukes of the Family Fasciolidae Inferred from Genome-Wide Comparisons of Key Species. PMID:31501870
Cell-type-specific analysis of alternative polyadenylation using single-cell transcriptomics data. PMID:31501864
Spodoptera frugiperda transcriptional response to infestation by Steinernema carpocapsae. PMID:31501491
Benchmarking variant identification tools for plant diversity discovery. PMID:31500583
Construction of a high-resolution genetic map and identification of quantitative trait loci for salt tolerance in jute (Corchous spp.). PMID:31500566
BINDER: computationally inferring a gene regulatory network for Mycobacterium abscessus. PMID:31500560
Monitoring the interplay between transposable element families and DNA methylation in maize. PMID:31498837
Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes. PMID:31498079
Characterizing microsatellite polymorphisms using assembly-based and mapping-based tools. PMID:31496881
X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation. PMID:31495695
Sperm competitive advantage of a rare mitochondrial haplogroup linked to differential expression of mitochondrial oxidative phosphorylation genes. PMID:31495025
High-quality Schistosoma haematobium genome achieved by single-molecule and long-range sequencing. PMID:31494670
Genomic evidence of neo-sex chromosomes in the eastern yellow robin. PMID:31494668
Similarities and differences in patterns of germline mutation between mice and humans. PMID:31492841
Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells. PMID:31492838
Degeneration of Injured Axons and Dendrites Requires Restraint of a Protective JNK Signaling Pathway by the Transmembrane Protein Raw. PMID:31492772
CRISPR-Cas System of a Prevalent Human Gut Bacterium Reveals Hyper-targeting against Phages in a Human Virome Catalog. PMID:31492655
The Draft Genome of the Endangered Sichuan Partridge (Arborophila rufipectus) with Evolutionary Implications. PMID:31491910
Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome. PMID:31491386
PIF transcription factors link a neighbor threat cue to accelerated reproduction in Arabidopsis. PMID:31488833
Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex. PMID:31488832
Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas. PMID:31488818
Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan. PMID:31488564
Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds. PMID:31488056
Altered gating of Kv1.4 in the nucleus accumbens suppresses motivation for reward. PMID:31487241
A comprehensive biomedical variant catalogue based on whole genome sequences of 582 dogs and eight wolves. PMID:31486122
The metabolic network model of primed/naive human embryonic stem cells underlines the importance of oxidation-reduction potential and tryptophan metabolism in primed pluripotency. PMID:31485322
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape. PMID:31485078
Identification of stably expressed housekeeping miRNAs in endothelial cells and macrophages in an inflammatory setting. PMID:31484960
Combination treatment with n-3 polyunsaturated fatty acids and ursodeoxycholic acid dissolves cholesterol gallstones in mice. PMID:31484954
Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations. PMID:31484939
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis. PMID:31484767
Host and geography together drive early adaptive radiation of Hawaiian planthoppers. PMID:31484218
Pinpointing the Genomic Localizations of Chromatin-Associated Proteins: The Yesterday, Today, and Tomorrow of ChIP-seq. PMID:31483109
Sentieon DNASeq Variant Calling Workflow Demonstrates Strong Computational Performance and Accuracy. PMID:31481971
Novel 5-Nitrofuran-Activating Reductase in Escherichia coli. PMID:31481448
Population genomics reveals possible genetic evidence for parallel evolution of Sebastiscus marmoratus in the northwestern Pacific Ocean. PMID:31480992
Twenty-Five Years of Propagation in Suspension Cell Culture Results in Substantial Alterations of the Arabidopsis Thaliana Genome. PMID:31480756
No excessive mutations in transcription activator-like effector nuclease-mediated α-1,3-galactosyltransferase knockout Yucatan miniature pigs. PMID:31480150
Genomic analysis reveals selection signatures of the Wannan Black pig during domestication and breeding. PMID:31480149
Single-amino acid variants reveal evolutionary processes that shape the biogeography of a global SAR11 subclade. PMID:31478833
Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma. PMID:31477832
CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation. PMID:31477705
Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy. PMID:31477698
Contrasting patterns of longitudinal population dynamics and antimicrobial resistance mechanisms in two priority bacterial pathogens over 7 years in a single center. PMID:31477167
Effect of CFIm68 knockdown on RNA polymerase II transcription. PMID:31477156
Mitochondrial genomic variation drives differential nuclear gene expression in discrete regions of Drosophila gene and protein interaction networks. PMID:31477008
Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo. PMID:31475747
Phylogenetic analysis of clinical strains of Helicobacter pylori isolated from patients with gastric diseases in Tibet. PMID:31475190
Prenatal Diagnosis of Fetuses With Increased Nuchal Translucency by Genome Sequencing Analysis. PMID:31475041
A Comparative Genome-Wide Analysis of the R2R3-MYB Gene Family Among Four Gossypium Species and Their Sequence Variation and Association With Fiber Quality Traits in an Interspecific G. hirsutum × G. barbadense Population. PMID:31475040
Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy. PMID:31474368
Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids. PMID:31472697
Sex-specific changes in the aphid DNA methylation landscape. PMID:31472081
Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments. PMID:31471491
Horizontal Gene Transfer and Acquired Antibiotic Resistance in Salmonella enterica Serovar Heidelberg following In Vitro Incubation in Broiler Ceca. PMID:31471306
Exploring Listeria monocytogenes Transcriptomes in Correlation with Divergence of Lineages and Virulence as Measured in Galleria mellonella. PMID:31471303
Lettuce Chlorosis Virus Disease: A New Threat to Cannabis Production. PMID:31470681
Genome-wide expression quantitative trait locus analysis in a recombinant inbred line population for trait dissection in peanut. PMID:31469515
The rhg1-a (Rhg1 low-copy) nematode resistance source harbors a copia-family retrotransposon within the Rhg1-encoded α-SNAP gene. PMID:31468029
Nonallelic homologous recombination events responsible for copy number variation within an RNA silencing locus. PMID:31468028
Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken. PMID:31467356
A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination. PMID:31467277
An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion. PMID:31467088
Metagenomic Analysis of Virus Diversity and Relative Abundance in a Eutrophic Freshwater Harbour. PMID:31466255
C3: Consensus Cancer Driver Gene Caller. PMID:31465854
Sequence-based mapping identifies a candidate transcription repressor underlying awn suppression at the B1 locus in wheat. PMID:31465541
Evaluation of the contribution of germline variants in BRCA1 and BRCA2 to uveal and cutaneous melanoma. PMID:31464824
Raptor genomes reveal evolutionary signatures of predatory and nocturnal lifestyles. PMID:31464627
A novel LAMP2 p.G93R mutation associated with mild Danon disease presenting with familial hypertrophic cardiomyopathy. PMID:31464081
Signatures of adaptive divergence among populations of an avian species of conservation concern. PMID:31462921
Range-wide population genomics of the Mexican fruit fly: Toward development of pathway analysis tools. PMID:31462920
Artificial selection causes significant linkage disequilibrium among multiple unlinked genes in Australian wheat. PMID:31462918
A highly mutagenised barley (cv. Golden Promise) TILLING population coupled with strategies for screening-by-sequencing. PMID:31462905
Bcl11b prevents catastrophic autoimmunity by controlling multiple aspects of a regulatory T cell gene expression program. PMID:31457081
Genomic Analyses Reveal Evidence of Independent Evolution, Demographic History, and Extreme Environment Adaptation of Tibetan Plateau Agaricus bisporus. PMID:31456761
Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms. PMID:31456751
The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation. PMID:31456285
Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia. PMID:31455887
Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage. PMID:31455884
Deformed wing virus type A, a major honey bee pathogen, is vectored by the mite Varroa destructor in a non-propagative manner. PMID:31455863
A Deep Learning Approach for Detecting Copy Number Variation in Next-Generation Sequencing Data. PMID:31455677
Extensive Thioautotrophic Gill Endosymbiont Diversity within a Single Ctena orbiculata (Bivalvia: Lucinidae) Population and Implications for Defining Host-Symbiont Specificity and Species Recognition. PMID:31455638
Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent. PMID:31455230
Genetic affinities of an eradicated European Plasmodium falciparum strain. PMID:31454309
Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nuts. PMID:31453381
Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. PMID:31452935
Comparing Ease of Programming in C++, Go, and Java for Implementing a Next-Generation Sequencing Tool. PMID:31452597
Transcriptome analysis to understand the effects of the toxoflavin and tropolone produced by phytopathogenic Burkholderia on Escherichia coli. PMID:31452043
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics. PMID:31451693
Mutant Huntingtin Affects Diabetes and Alzheimer's Markers in Human and Cell Models of Huntington's Disease. PMID:31450785
Scanning of Genetic Variants and Genetic Mapping of Phenotypic Traits in Gilthead Sea Bream Through ddRAD Sequencing. PMID:31447879
Fishing in the Soup - Pathogen Detection in Food Safety Using Metabarcoding and Metagenomic Sequencing. PMID:31447815
Niche differentiation among annually recurrent coastal Marine Group II Euryarchaeota. PMID:31447484
Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. PMID:31445886
Gene co-expression network analysis reveals pathways associated with graft healing by asymmetric profiling in tomato. PMID:31445524
HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus. PMID:31444406
Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening. PMID:31444346
DNA Testing Reveals the Putative Identity of JB55, a 19th Century Vampire Buried in Griswold, Connecticut. PMID:31443502
Cyprinid herpesvirus 3 Evolves In Vitro through an Assemblage of Haplotypes that Alternatively Become Dominant or Under-Represented. PMID:31443175
A novel compound heterozygous KCNJ1 gene mutation presenting as late-onset Bartter syndrome: Case report. PMID:31441846
Tracking Carbapenem-Producing Klebsiella pneumoniae Outbreak in an Intensive Care Unit by Whole Genome Sequencing. PMID:31440476
Efficient Mining of Variants From Trios for Ventricular Septal Defect Association Study. PMID:31440271
Single Primer Enrichment Technology (SPET) for High-Throughput Genotyping in Tomato and Eggplant Germplasm. PMID:31440267
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma-A Proof of Antigen Discovery Feasibility in Three Patients. PMID:31440238
Molecular Evolution of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa Strains From Patients and Hospital Environment in a Prolonged Outbreak. PMID:31440214
Efficient and specific oligo-based depletion of rRNA. PMID:31439880
The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis. PMID:31439835
PARP Inhibition Suppresses GR-MYCN-CDK5-RB1-E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer. PMID:31439587
Evaluating responses to temperature during pre-metamorphosis and carry-over effects at post-metamorphosis in the wood tiger moth (Arctia plantaginis). PMID:31438813
Depletion of the Transcriptional Coactivator Amplified in Breast Cancer 1 (AIB1) Uncovers Functionally Distinct Subpopulations in Triple-Negative Breast Cancer. PMID:31437536
Next generation long-culm rice with superior lodging resistance and high grain yield, Monster Rice 1. PMID:31437205
Complex interplay of evolutionary forces shaping population genomic structure of invasive Aedes albopictus in southern Europe. PMID:31437154
Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation. PMID:31437150
A de novo evolved gene in the house mouse regulates female pregnancy cycles. PMID:31436535
Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes. PMID:31436530
Sex-specific transcriptomic responses to changes in the nutritional environment. PMID:31436529
Conservation genomic analysis reveals ancient introgression and declining levels of genetic diversity in Madagascar's hibernating dwarf lemurs. PMID:31435007
Wilm's tumor 1 promotes memory flexibility. PMID:31434897
Identification and Characterization of New Variants in FOXRED1 Gene Expands the Clinical Spectrum Associated with Mitochondrial Complex I Deficiency. PMID:31434271
Chromatin Remodeling in Response to BRCA2-Crisis. PMID:31433991
miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival. PMID:31433990
Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons. PMID:31433982
Comparison of single-nucleotide variants identified by Illumina and Oxford Nanopore technologies in the context of a potential outbreak of Shiga toxin-producing Escherichia coli. PMID:31433830
Cranial deformation and genetic diversity in three adolescent male individuals from the Great Migration Period from Osijek, eastern Croatia. PMID:31433816
Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1. PMID:31433295
Toward on-site food authentication using nanopore sequencing. PMID:31432019
Identification of Recurrent Activating HER2 Mutations in Primary Canine Pulmonary Adenocarcinoma. PMID:31431454
Multi-Omics Characterization of the Spontaneous Mesenchymal-Epithelial Transition in the PMC42 Breast Cancer Cell Lines. PMID:31430931
The draft genome sequence of the spider Dysdera silvatica (Araneae, Dysderidae): A valuable resource for functional and evolutionary genomic studies in chelicerates. PMID:31430368
Osteogenesis imperfecta in Brazilian patients. PMID:31429852
De novo profiling of RNA viruses in Anopheles malaria vector mosquitoes from forest ecological zones in Senegal and Cambodia. PMID:31429704
TDNAscan: A Software to Identify Complete and Truncated T-DNA Insertions. PMID:31428129
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. PMID:31427770
Developmental plasticity of epithelial stem cells in tooth and taste bud renewal. PMID:31427537
Genome-Wide Transcription Factor Binding in Leaves from C3 and C4 Grasses. PMID:31427470
Utilization of Tissue Ploidy Level Variation in de Novo Transcriptome Assembly of Pinus sylvestris. PMID:31427456
A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing. PMID:31427386
Validating the AMRFinder Tool and Resistance Gene Database by Using Antimicrobial Resistance Genotype-Phenotype Correlations in a Collection of Isolates. PMID:31427293
TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2. PMID:31426913
Genes Controlled by DNA Methylation Are Involved in Wilms Tumor Progression. PMID:31426508
Contemporary Demographic Reconstruction Methods Are Robust to Genome Assembly Quality: A Case Study in Tasmanian Devils. PMID:31424552
Comparative Genomic Characterization of the Multimammate Mouse Mastomys coucha. PMID:31424545
Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells. PMID:31422913
Distinct Molecular Trajectories Converge to Induce Naive Pluripotency. PMID:31422912
Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7. PMID:31422906
Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs. PMID:31422875
Application of a high-resolution genetic map for chromosome-scale genome assembly and fine QTLs mapping of seed size and weight traits in castor bean. PMID:31420567
High-Level Abundances of Methanobacteriales and Syntrophobacterales May Help To Prevent Corrosion of Metal Sheet Piles. PMID:31420342
Single-base methylome profiling of the giant kelp Saccharina japonica reveals significant differences in DNA methylation to microalgae and plants. PMID:31419316
Epigenetic silencing of a multifunctional plant stress regulator. PMID:31418686
DNA Analysis by Restriction Enzyme (DARE) enables concurrent genomic and epigenomic characterization of single cells. PMID:31418018
Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models. PMID:31418010
Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens. PMID:31417509
Inhibition of DOT1L and PRMT5 promote synergistic anti-tumor activity in a human MLL leukemia model induced by CRISPR/Cas9. PMID:31417187
An automated pipeline for the screening of diverse monoterpene synthase libraries. PMID:31417136
Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression. PMID:31415754
Genetic and clinical predictors of CD4 lymphocyte recovery during suppressive antiretroviral therapy: Whole exome sequencing and antiretroviral therapy response phenotypes. PMID:31415590
Decreased metabolism and increased tolerance to extreme environments in Staphylococcus warneri during long-term spaceflight. PMID:31414557
Signatures of differential selection in chloroplast genome between japonica and indica. PMID:31414311
Genome-wide analysis sheds light on the high-altitude adaptation of the buff-throated partridge (Tetraophasis szechenyii). PMID:31414227
A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing. PMID:31413257
Geochemical and Metagenomic Characterization of Jinata Onsen, a Proterozoic-Analog Hot Spring, Reveals Novel Microbial Diversity including Iron-Tolerant Phototrophs and Thermophilic Lithotrophs. PMID:31413226
Dominant Negative MA-CA Fusion Protein Is Incorporated into HIV-1 Cores and Inhibits Nuclear Entry of Viral Preintegration Complexes. PMID:31413124
Extreme-QTL mapping of monepantel resistance in Haemonchus contortus. PMID:31412938
The first genetic map for yellow lupin enables genetic dissection of adaptation traits in an orphan grain legume crop. PMID:31412771
Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti. PMID:31412040
Kettin, the large actin-binding protein with multiple immunoglobulin domains, is essential for sarcomeric actin assembly and larval development in Caenorhabditis elegans. PMID:31411810
A genetic selection reveals functional metastable structures embedded in a toxin-encoding mRNA. PMID:31411564
Viral composition and context in metagenomes from biofilm and suspended growth municipal wastewater treatment plants. PMID:31410982
Chromatin loops associated with active genes and heterochromatin shape rice genome architecture for transcriptional regulation. PMID:31409785
Evolution of the RNA N 6-Methyladenosine Methylome Mediated by Genomic Duplication. PMID:31409695
Aggregation of Nontuberculous Mycobacteria Is Regulated by Carbon-Nitrogen Balance. PMID:31409683
A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus. PMID:31409681
Application of mini-MLST and whole genome sequencing in low diversity hospital extended-spectrum beta-lactamase producing Klebsiella pneumoniae population. PMID:31408497
Insertional oncogenesis by HPV70 revealed by multiple genomic analyses in a clinically HPV-negative cervical cancer. PMID:31407403
Complete genome and plasmid sequence of a novel Bacillus sp. BD59S, a parasporal protein synthesizing bacterium. PMID:31406640
Unravelling the genes forming the wing pattern supergene in the polymorphic butterfly Heliconius numata. PMID:31406559
Worldwide human mitochondrial haplogroup distribution from urban sewage. PMID:31406241
The BACH1-HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration. PMID:31405954
MARPLE, a point-of-care, strain-level disease diagnostics and surveillance tool for complex fungal pathogens. PMID:31405370
Generation of Virus- and dsRNA-Derived siRNAs with Species-Dependent Length in Insects. PMID:31405199
ShapeShifter: a novel approach for identifying and quantifying stable lariat intronic species in RNAseq data. PMID:31404415
P Granules Protect RNA Interference Genes from Silencing by piRNAs. PMID:31402283
Gene Fusions Derived by Transcriptional Readthrough are Driven by Segmental Duplication in Human. PMID:31400206
The population genetics of crypsis in vertebrates: recent insights from mice, hares, and lizards. PMID:31399719
Genomic analyses reveal three independent introductions of the invasive brown rat (Rattus norvegicus) to the Faroe Islands. PMID:31399718
Expanding C-T base editing toolkit with diversified cytidine deaminases. PMID:31399578
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer. PMID:31399573
The pause-initiation limit restricts transcription activation in human cells. PMID:31399571
Exploring the Phylogeography of Ancient Platycladus orientalis in China by Specific-Locus Amplified Fragment Sequencing. PMID:31398898
CAG Repeat Not Polyglutamine Length Determines Timing of Huntington's Disease Onset. PMID:31398342
Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks. PMID:31398340
Remodeling of the Caenorhabditis elegans non-coding RNA transcriptome by heat shock. PMID:31396626
Nested retrotransposition in the East Asian mouse genome causes the classical nonagouti mutation. PMID:31396563
The revised complete mitogenome sequence of the tree frog Polypedatesmegacephalus (Anura, Rhacophoridae) by next-generation sequencing and phylogenetic analysis. PMID:31396450
Increase in DNA Damage by MYCN Knockdown Through Regulating Nucleosome Organization and Chromatin State in Neuroblastoma. PMID:31396265
Identification of a Dominant Chlorosis Phenotype Through a Forward Screen of the Triticum turgidum cv. Kronos TILLING Population. PMID:31396255
Horizontally transmitted symbiont populations in deep-sea mussels are genetically isolated. PMID:31395952
Elucidating Drought Stress Tolerance in European Oaks Through Cross-Species Transcriptomics. PMID:31395652
Evolution of Attenuation and Risk of Reversal in Peste des Petits Ruminants Vaccine Strain Nigeria 75/1. PMID:31394790
Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells. PMID:31393266
Burkholderia multivorans Exhibits Antibiotic Collateral Sensitivity. PMID:31393205
Analyzing whole genome bisulfite sequencing data from highly divergent genotypes. PMID:31392989
Simultaneous precise editing of multiple genes in human cells. PMID:31392986
AGO-unbound cytosolic pool of mature miRNAs in plant cells reveals a novel regulatory step at AGO1 loading. PMID:31392979
CROSSMAPPER: estimating cross-mapping rates and optimizing experimental design in multi-species sequencing studies. PMID:31392323
The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4. PMID:31392315
Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot. PMID:31392031
Population Genomics Analysis Revealed Origin and High-altitude Adaptation of Tibetan Pigs. PMID:31391504
ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion. PMID:31391455
Long Non-Coding RNA Expression Levels Modulate Cell-Type-Specific Splicing Patterns by Altering Their Interaction Landscape with RNA-Binding Proteins. PMID:31390792
Constructing a Reference Genome in a Single Lab: The Possibility to Use Oxford Nanopore Technology. PMID:31390788
A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation. PMID:31390566
An improved genome assembly of the fluke Schistosoma japonicum. PMID:31390359
Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism. PMID:31389636
Genomics of rapid ecological divergence and parallel adaptation in four tidal marsh sparrows. PMID:31388443
Elucidating Syntrophic Butyrate-Degrading Populations in Anaerobic Digesters Using Stable-Isotope-Informed Genome-Resolved Metagenomics. PMID:31387934
The Oral Mouse Microbiome Promotes Tumorigenesis in Oral Squamous Cell Carcinoma. PMID:31387932
Transcriptomic differences noted in Glaesserella parasuis between growth in broth and on agar. PMID:31386681
Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts. PMID:31385397
Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development. PMID:31384004
A simple, reproducible and cost-effective procedure to analyse gut phageome: from phage isolation to bioinformatic approach. PMID:31383878
Integrated genomic epidemiology and phenotypic profiling of Clostridium difficile across intra-hospital and community populations in Colombia. PMID:31383872
Transcriptome Analysis of Young Ovaries Reveals Candidate Genes Involved in Gamete Formation in Lantana camara. PMID:31382394
Methyl-CpG-binding domain 9 (MBD9) is required for H2A.Z incorporation into chromatin at a subset of H2A.Z-enriched regions in the Arabidopsis genome. PMID:31381567
Signals of positive selection in mitochondrial protein-coding genes of woolly mammoth: Adaptation to extreme environments? PMID:31380018
Whole-Genome Resequencing Reveals Loci Associated With Thoracic Vertebrae Number in Sheep. PMID:31379930
Depletion of Hemoglobin Transcripts and Long-Read Sequencing Improves the Transcriptome Annotation of the Polar Bear (Ursus maritimus). PMID:31379921
Ammonia Oxidation by the Arctic Terrestrial Thaumarchaeote Candidatus Nitrosocosmicus arcticus Is Stimulated by Increasing Temperatures. PMID:31379764
SeQuiLa-cov: A fast and scalable library for depth of coverage calculations. PMID:31378808
Compendium of 4,941 rumen metagenome-assembled genomes for rumen microbiome biology and enzyme discovery. PMID:31375809
Functional genetic variants can mediate their regulatory effects through alteration of transcription factor binding. PMID:31375681
Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2. PMID:31375664
Independent Evolution with the Gene Flux Originating from Multiple Xanthomonas Species Explains Genomic Heterogeneity in Xanthomonas perforans. PMID:31375496
Typing of mecD Islands in Genetically Diverse Methicillin-Resistant Macrococcus caseolyticus Strains from Cattle. PMID:31375493
Effects of Methanol on Carotenoids as Well as Biomass and Fatty Acid Biosynthesis in Schizochytrium limacinum B4D1. PMID:31375482
Identification of single nucleotide variants using position-specific error estimation in deep sequencing data. PMID:31375105
circMeta: a unified computational framework for genomic feature annotation and differential expression analysis of circular RNAs. PMID:31373611
Malaria.tools-comparative genomic and transcriptomic database for Plasmodium species. PMID:31372645
A Receptor Tyrosine Kinase Plays Separate Roles in Sensory Integration and Associative Learning in C. elegans. PMID:31371455
Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells. PMID:31371436
Genetic Mapping of Prince Rupprecht's Larch (Larix principis-rupprechtii Mayr) by Specific-Locus Amplified Fragment Sequencing. PMID:31370324
SNV discovery and functional candidate gene identification for milk composition based on whole genome resequencing of Holstein bulls with extremely high and low breeding values. PMID:31369641
Nuclear RNA export factor variant initiates piRNA-guided co-transcriptional silencing. PMID:31368590
Frankia-Enriched Metagenomes from the Earliest Diverging Symbiotic Frankia Cluster: They Come in Teams. PMID:31368478
Uncovering missed indels by leveraging unmapped reads. PMID:31366961
Sequencing of Chinese castor lines reveals genetic signatures of selection and yield-associated loci. PMID:31366935
A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes. PMID:31366910
Transposition favors the generation of large effect mutations that may facilitate rapid adaption. PMID:31366887
Translocation of Dense Granule Effectors across the Parasitophorous Vacuole Membrane in Toxoplasma-Infected Cells Requires the Activity of ROP17, a Rhoptry Protein Kinase. PMID:31366709
HUPAN: a pan-genome analysis pipeline for human genomes. PMID:31366358
Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network. PMID:31366319
Early Colorectal Cancers Provide New Evidence for a Lynch Syndrome-to-CMMRD Phenotypic Continuum. PMID:31366136
Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo. PMID:31365523
Comparison of the sequencing bias of currently available library preparation kits for Illumina sequencing of bacterial genomes and metagenomes. PMID:31364694
KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity. PMID:31363749
Genetic basis of functional variability in adhesion G protein-coupled receptors. PMID:31363148
Histone acetylation recruits the SWR1 complex to regulate active DNA demethylation in Arabidopsis. PMID:31363048
Dissecting the Gene Expression, Localization, Membrane Topology, and Function of the Plasmodium falciparum STEVOR Protein Family. PMID:31363031
Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy. PMID:31363023
Estrogen-independent molecular actions of mutant estrogen receptor 1 in endometrial cancer. PMID:31362937
Whole-genome comparison between reference sequences and oyster Vibrio vulnificus C-genotype strains. PMID:31361763
AluMine: alignment-free method for the discovery of polymorphic Alu element insertions. PMID:31360240
An evaluation of sequencing coverage and genotyping strategies to assess neutral and adaptive diversity. PMID:31359622
Genome-wide identification and expression analysis of Hsp70, Hsp90, and Hsp100 heat shock protein genes in barley under stress conditions and reproductive development. PMID:31359217
The impact of antimicrobials on gonococcal evolution. PMID:31358980
Assessment of genetic variant burden in epilepsy-associated brain lesions. PMID:31358956
Extensive post-transcriptional buffering of gene expression in the response to severe oxidative stress in baker's yeast. PMID:31358845
High prevalence of the MLH1 V384D germline mutation in patients with HER2-positive luminal B breast cancer. PMID:31358837
Lack of long-term acclimation in Antarctic encrusting species suggests vulnerability to warming. PMID:31358752
Timing Is Everything: Impact of Naturally Occurring Staphylococcus aureus AgrC Cytoplasmic Domain Adaptive Mutations on Autoinduction. PMID:31358609
Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma. PMID:31358475
Long noncoding RNA CCDC144NL-AS1 knockdown induces naïve-like state conversion of human pluripotent stem cells. PMID:31358062
Challenges in funding and developing genomic software: roots and remedies. PMID:31358028
An unusual case of bovine anthrax in the canton of Jura, Switzerland in 2017. PMID:31357988
Epimutations are associated with CHROMOMETHYLASE 3-induced de novo DNA methylation. PMID:31356150
Variability in Genomic and Virulent Properties of Porphyromonas gingivalis Strains Isolated From Healthy and Severe Chronic Periodontitis Individuals. PMID:31355151
Extreme Diversity of Mycoviruses Present in Isolates of Rhizoctonia solani AG2-2 LP From Zoysia japonica From Brazil. PMID:31355150
Metagenomic analysis of bacterial endophyte community structure and functions in Panax ginseng at different ages. PMID:31355109
An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development. PMID:31354981
Differentiations in Gene Content and Expression Response to Virulence Induction Between Two Agrobacterium Strains. PMID:31354658
A genome-wide screen identifies IRF2 as a key regulator of caspase-4 in human cells. PMID:31353801
FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue. PMID:31352405
MALVA: Genotyping by Mapping-free ALlele Detection of Known VAriants. PMID:31352182
Differentially methylated regions in bipolar disorder and suicide. PMID:31350827
An 'eFP-Seq Browser' for visualizing and exploring RNA sequencing data. PMID:31350781
Evidence for selection events during domestication by extensive mitochondrial genome analysis between japonica and indica in cultivated rice. PMID:31350452
Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis. PMID:31350386
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations. PMID:31350336
The genome of the live-bearing fish Heterandria formosa implicates a role of conserved vertebrate genes in the evolution of placental fish. PMID:31349784
SiNPle: Fast and Sensitive Variant Calling for Deep Sequencing Data. PMID:31349684
Human Artificial Chromosomes that Bypass Centromeric DNA. PMID:31348889
The presence and impact of reference bias on population genomic studies of prehistoric human populations. PMID:31348818
FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science. PMID:31346170
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma. PMID:31346162
Whole-Genome Sequencing and Annotation of Clostridium tyrobutyricum Strain Cirm BIA 2237, Isolated from Silage. PMID:31346011
Centromere-Proximal Meiotic Crossovers in Drosophila melanogaster Are Suppressed by Both Highly Repetitive Heterochromatin and Proximity to the Centromere. PMID:31345993
Magic-BLAST, an accurate RNA-seq aligner for long and short reads. PMID:31345161
Eye in a Disk: eyeIntegration Human Pan-Eye and Body Transcriptome Database Version 1.0. PMID:31343654
Genetic diversity of the Sichuan snub-nosed monkey (Rhinopithecus roxellana) in Shennongjia National Park, China using RAD-seq analyses. PMID:31342301
Comparative Genomics Analysis in Grass Species Reveals Two Distinct Evolutionary Strategies Adopted by R Genes. PMID:31341223
Identification of city specific important bacterial signature for the MetaSUB CAMDA challenge microbiome data. PMID:31340852
Quantitative assessment of LASSO probe assembly and long-read multiplexed cloning. PMID:31340783
Rapid metagenomics analysis of EMS vehicles for monitoring pathogen load using nanopore DNA sequencing. PMID:31339905
Genetic polymorphisms and transcription profiles associated with intracranial aneurysm: a key role for NOTCH3. PMID:31339861
Comparative genomic analyses of two segregating mutants reveal seven genes likely involved in resistance to Fusarium equiseti in soybean via whole genome re-sequencing. PMID:31338526
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II. PMID:31337748
Isolation of Open Chromatin Identifies Regulators of Systemic Acquired Resistance. PMID:31337712
Chromatin Interaction Analysis with Updated ChIA-PET Tool (V3). PMID:31336684
Molecular Characterisation of a Supergene Conditioning Super-High Vitamin C in Kiwifruit Hybrids. PMID:31336644
Genome-wide discovery of the daily transcriptome, DNA regulatory elements and transcription factor occupancy in the monarch butterfly brain. PMID:31335862
Phased genome sequence of an interspecific hybrid flowering cherry, 'Somei-Yoshino' (Cerasus × yedoensis). PMID:31334758
sRNA Profiling Combined With Gene Function Analysis Reveals a Lack of Evidence for Cross-Kingdom RNAi in the Wheat - Zymoseptoria tritici Pathosystem. PMID:31333714
Pan-Genomic and Polymorphic Driven Prediction of Antibiotic Resistance in Elizabethkingia. PMID:31333599
Identification of Clinical Infections of Leishmania Imported into Australia: Revising Speciation with Polymerase Chain Reaction-RFLP of the Kinetoplast Maxicircle. PMID:31333156
Genome-Wide Association Study of Growth and Body-Shape-Related Traits in Large Yellow Croaker (Larimichthys crocea) Using ddRAD Sequencing. PMID:31332575
Transcriptome sequencing, molecular markers, and transcription factor discovery of Platanus acerifolia in the presence of Corythucha ciliata. PMID:31332220
Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages. PMID:31332179
Revealing the pathogenic changes of PAH based on multiomics characteristics. PMID:31331330
Genome survey and high-resolution backcross genetic linkage map construction of the ridgetail white prawn Exopalaemon carinicauda applications to QTL mapping of growth traits. PMID:31331278
A high density SLAF-seq SNP genetic map and QTL for seed size, oil and protein content in upland cotton. PMID:31331266
Polynucleotide phosphorylase promotes the stability and function of Hfq-binding sRNAs by degrading target mRNA-derived fragments. PMID:31329973
Evolutionary Dynamics of Sex Chromosomes of Paleognathous Birds. PMID:31329234
DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade. PMID:31327741
TRANSPORTER OF IBA1 Links Auxin and Cytokinin to Influence Root Architecture. PMID:31327740
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. PMID:31327655
Gut Colonization Preceding Mucosal Barrier Injury Bloodstream Infection in Pediatric Hematopoietic Stem Cell Transplantation Recipients. PMID:31326608
The clinical and radiological profile of primary lateral sclerosis: a population-based study. PMID:31325016
Identification and characterization of a fast-neutron-induced mutant with elevated seed protein content in soybean. PMID:31324928
Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients. PMID:31324819
De novo phased assembly of the Vitis riparia grape genome. PMID:31324816
Genomic and Seasonal Variations among Aquatic Phages Infecting the Baltic Sea Gammaproteobacterium Rheinheimera sp. Strain BAL341. PMID:31324626
Gene expression profile of human T cells following a single stimulation of peripheral blood mononuclear cells with anti-CD3 antibodies. PMID:31324145
Genome and transcriptome characterization of the glycoengineered Nicotiana benthamiana line ΔXT/FT. PMID:31324144
Computational Processing and Quality Control of Hi-C, Capture Hi-C and Capture-C Data. PMID:31323892
Expanding the repertoire of conservative site-specific recombination in Clostridioides difficile. PMID:31323290
Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages. PMID:31323189
Novel protective and risk loci in hip dysplasia in German Shepherds. PMID:31323019
The distribution of fitness effects among synonymous mutations in a gene under directional selection. PMID:31322500
Identification of a novel mutation site in maturity‑onset diabetes of the young in a Chinese family by whole‑exome sequencing. PMID:31322178
Spatiotemporal Gene Coexpression and Regulation in Mouse Cardiomyocytes of Early Cardiac Morphogenesis. PMID:31322043
Whole-exome sequencing of familial esophageal squamous cell carcinoma identified rare pathogenic variants in new predisposition genes. PMID:31321674
CWL-Airflow: a lightweight pipeline manager supporting Common Workflow Language. PMID:31321430
Data describing the effects of depletion of Myoparr, myogenin, Ddx17, and hnRNPK in differentiating C2C12 cells. PMID:31321265
Genome-Wide Identification of Putative MicroRNAs in Cassava (Manihot esculenta Crantz) and Their Functional Landscape in Cellular Regulation. PMID:31321230
Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets. PMID:31320640
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. PMID:31320637
The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes. PMID:31320616
Genetic control of male production in Daphnia pulex. PMID:31320584
Phylogenomic Analyses Clarify True Species within the Butterfly Genus Speyeria despite Evidence of a Recent Adaptive Radiation. PMID:31319462
Whole-exome sequencing and immunohistochemistry findings in von Hippel-Lindau disease. PMID:31317677
Next-generation sequencing-based bulked segregant analysis for QTL mapping in the heterozygous species Brassica rapa. PMID:31317235
Comparative Transcriptome Analysis Reveals Molecular Basis Underlying Fast Growth of the Selectively Bred Pacific Oyster, Crassostrea gigas. PMID:31316550
Sequence Dynamics of Pre-mRNA G-Quadruplexes in Plants. PMID:31316532
Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing. PMID:31316107
The genome assembly of asparagus bean, Vigna unguiculata ssp. sesquipedialis. PMID:31316072
Whole-Genome Sequencing Reveals a Prolonged and Persistent Intrahospital Transmission of Corynebacterium striatum, an Emerging Multidrug-Resistant Pathogen. PMID:31315959
Minimal Effects of Proto-Y Chromosomes on House Fly Gene Expression in Spite of Evidence that Selection Maintains Stable Polygenic Sex Determination. PMID:31315889
The draft genome of a wild barley genotype reveals its enrichment in genes related to biotic and abiotic stresses compared to cultivated barley. PMID:31314154
Ultraconserved element (UCE) probe set design: Base genome and initial design parameters critical for optimization. PMID:31312430
Natural Killer Cell Receptor Genes in Camels: Another Mammalian Model. PMID:31312212
Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation. PMID:31311937
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. PMID:31311926
Centromere Satellite Repeats Have Undergone Rapid Changes in Polyploid Wheat Subgenomes. PMID:31311836
A multivariate Poisson-log normal mixture model for clustering transcriptome sequencing data. PMID:31311497
Convergent evolution of cytochrome P450s underlies independent origins of keto-carotenoid pigmentation in animals. PMID:31311468
Rare variant in LAMA2 gene causing congenital muscular dystrophy in a Sudanese family. A case report. PMID:31309178
Musa balbisiana genome reveals subgenome evolution and functional divergence. PMID:31308504
Identification and validation of SNP markers linked to seed toxicity in Jatropha curcas L. PMID:31308439
REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output. PMID:31308426
A herpesvirus transactivator and cellular POU proteins extensively regulate DNA binding of the host Notch signaling protein RBP-Jκ to the virus genome. PMID:31308175
A pollution gradient contributes to the taxonomic, functional, and resistome diversity of microbial communities in marine sediments. PMID:31307536
Recurrent miscalling of missense variation from short-read genome sequence data. PMID:31307400
De novo genome assembly of the endangered Acer yangbiense, a plant species with extremely small populations endemic to Yunnan Province, China. PMID:31307060
Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma. PMID:31306413
Visualization and analysis of RNA-Seq assembly graphs. PMID:31305886
Draft genome sequence data of Bifidobacterium longum strain VKPM Ac-1636, a prospective probiotic isolated from human gut. PMID:31304205
Engineering Forward Genetics into Cultured Cancer Cells for Chemical Target Identification. PMID:31303577
Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. PMID:31303423
A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. PMID:31303374
CCMG practice guideline: laboratory guidelines for next-generation sequencing. PMID:31300550
Global Analysis of Furfural-Induced Genomic Instability Using a Yeast Model. PMID:31300396
Genome-wide mapping and profiling of γH2AX binding hotspots in response to different replication stress inducers. PMID:31299901
Alternative polyadenylation produces multiple 3' untranslated regions of odorant receptor mRNAs in mouse olfactory sensory neurons. PMID:31299892
Functional interplay between Mediator and RNA polymerase II in Rad2/XPG loading to the chromatin. PMID:31299084
ChIP-exo analysis highlights Fkh1 and Fkh2 transcription factors as hubs that integrate multi-scale networks in budding yeast. PMID:31299083
SSBP1 mutations in dominant optic atrophy with variable retinal degeneration. PMID:31298765
Genome Resequencing Reveals Congenital Causes of Embryo and Nestling Death in Crested Ibis (Nipponia nippon). PMID:31298688
Comprehensive mismatch repair gene panel identifies variants in patients with Lynch-like syndrome. PMID:31297992
Pioneer and repressive functions of p63 during zebrafish embryonic ectoderm specification. PMID:31296872
Retention of paternal DNA methylome in the developing zebrafish germline. PMID:31296860
Genomic Insight into Three Marine Micromonospora sp. Strains from the Gulf of California. PMID:31296693
GWAS for Meat and Carcass Traits Using Imputed Sequence Level Genotypes in Pooled F2-Designs in Pigs. PMID:31296617
CoMutPlotter: a web tool for visual summary of mutations in cancer cohorts. PMID:31296206
Divergent transcriptomic signatures in response to salinity exposure in two populations of an estuarine fish. PMID:31293632
Dissecting in silico Mutation Prediction of Variants in African Genomes: Challenges and Perspectives. PMID:31293624
Chromosomal Locations and Interactions of Four Loci Associated With Seed Coat Color in Watermelon. PMID:31293604
Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A. PMID:31293546
Genetic Diversity, Virulence, Race Profiling, and Comparative Genomic Analysis of the Fusarium oxysporum f. sp. conglutinans Strains Infecting Cabbages in China. PMID:31293534
GEAMP, a novel gastroesophageal junction carcinoma cell line derived from a malignant pleural effusion. PMID:31292541
Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the rDNA of Saccharomyces cerevisiae. PMID:31292210
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition. PMID:31291582
Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis. PMID:31291573
Identifying, understanding, and correcting technical artifacts on the sex chromosomes in next-generation sequencing data. PMID:31289836
Chromosomal-level assembly of the blood clam, Scapharca (Anadara) broughtonii, using long sequence reads and Hi-C. PMID:31289832
Epimutations in Developmental Genes Underlie the Onset of Domestication in Farmed European Sea Bass. PMID:31289822
Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex. PMID:31289266
Metabolic Model of the Phytophthora infestans-Tomato Interaction Reveals Metabolic Switches during Host Colonization. PMID:31289172
Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer. PMID:31287991
Managing genomic variant calling workflows with Swift/T. PMID:31287816
Comprehensive subspecies identification of 175 nontuberculous mycobacteria species based on 7547 genomic profiles. PMID:31287781
Classification of Mycobacterium tuberculosis DR, MDR,XDR Isolates and Identification of Signature MutationPattern of Drug Resistance. PMID:31285643
Global phylogeography and ancient evolution of the widespread human gut virus crAssphage. PMID:31285584
Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genetic exchange events between Malaysian Peninsular and Borneo subpopulations. PMID:31285495
Responses of tundra soil microbial communities to half a decade of experimental warming at two critical depths. PMID:31285347
Genomic Analysis Identifies Novel Pseudomonas aeruginosa Resistance Genes under Selection during Inhaled Aztreonam Therapy In Vivo. PMID:31285231
Improving Species Identification of Ancient Mammals Based on Next-Generation Sequencing Data. PMID:31284503
What drives phenotypic divergence among coral clonemates of Acropora palmata? PMID:31282031
High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells. PMID:31281593
Integration of metabolomics and expression of enolase-phosphatase 1 links to hepatocellular carcinoma progression. PMID:31281503
Complete Assembly of the Genome of an Acidovorax citrulli Strain Reveals a Naturally Occurring Plasmid in This Species. PMID:31281298
Continuous Culture Adaptation of Methylobacterium extorquens AM1 and TK 0001 to Very High Methanol Concentrations. PMID:31281294
Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stage. PMID:31279340
Comparative transcriptome analysis of cultivated and wild seeds of Salvia hispanica (chia). PMID:31278279
The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment. PMID:31278262
Clinically-relevant postzygotic mosaicism in parents and children with developmental disorders in trio exome sequencing data. PMID:31278258
Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling. PMID:31278255
Extensive intraspecific gene order and gene structural variations in upland cotton cultivars. PMID:31278252
HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding. PMID:31278053
The role of clonal communication and heterogeneity in breast cancer. PMID:31277602
Inositol pyrophosphates impact phosphate homeostasis via modulation of RNA 3' processing and transcription termination. PMID:31276588
Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging. PMID:31276581
A Genome-Wide Association Study of Non-Photochemical Quenching in response to local seasonal climates in Arabidopsis thaliana. PMID:31276082
Gauging genetic diversity of generalists: A test of genetic and ecological generalism with RNA virus experimental evolution. PMID:31275611
Genome-Wide Signatures of Selection in Colletotrichum kahawae Reveal Candidate Genes Potentially Involved in Pathogenicity and Aggressiveness. PMID:31275287
Opposite Expression Patterns of Spry3 and p75NTR in Cerebellar Vermis Suggest a Male-Specific Mechanism of Autism Pathogenesis. PMID:31275178
Molecular cloning of flavonoid biosynthetic genes and biochemical characterization of anthocyanin O-methyltransferase of Nemophila menziesii Hook. and Arn. PMID:31275032
QTL-seq reveals a major root-knot nematode resistance locus on chromosome 11 in rice (Oryza sativa L.). PMID:31274875
EPAS1 gain-of-function mutation contributes to high-altitude adaptation in Tibetan horses. PMID:31273382
Cas9-based enrichment and single-molecule sequencing for precise characterization of genomic duplications. PMID:31273287
Plug-and-Play Protein Modification Using Homology-Independent Universal Genome Engineering. PMID:31272828
Transcriptional reprogramming caused by the geminivirus Tomato yellow leaf curl virus in local or systemic infections in Nicotiana benthamiana. PMID:31272383
Transcriptome analysis of the fish pathogen Flavobacterium columnare in biofilm suggests calcium role in pathogenesis. PMID:31272369
Somatic mutations and cell identity linked by Genotyping of Transcriptomes. PMID:31270458
Chronic disturbance in the thalamus following cranial irradiation to the developing mouse brain. PMID:31270437
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines. PMID:31270247
Complete Genome Sequences of 10 Xanthomonas oryzae pv. oryzae Bacteriophages. PMID:31270189
Draft Genome Sequences of Eight Canadian Citrobacter braakii and Citrobacter freundii Strains. PMID:31270188
Landscape of Overlapping Gene Expression in the Equine Placenta. PMID:31269762
Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression. PMID:31269445
Characterization of genes and alleles involved in the control of flowering time in grapevine. PMID:31269026
A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription. PMID:31266943
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia. PMID:31266935
Roles for Stress Response and Cell Wall Biosynthesis Pathways in Caspofungin Tolerance in Cryptococcus neoformans. PMID:31266771
H3K4me2 functions as a repressive epigenetic mark in plants. PMID:31266517
BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity. PMID:31266503
SRAssembler: Selective Recursive local Assembly of homologous genomic regions. PMID:31266441
Recurrent DMD Deletions Highlight Specific Role of Dp71 Isoform in Soft-Tissue Sarcomas. PMID:31266185
Mapping of scaffold/matrix attachment regions in human genome: a data mining exercise. PMID:31265077
Residual β cell function and monogenic variants in long-duration type 1 diabetes patients. PMID:31264968
Massive postglacial gene flow between European white oaks uncovered genes underlying species barriers. PMID:31264219
Endangered island endemic plants have vulnerable genomes. PMID:31263788
Characterization of functional relationships of R-loops with gene transcription and epigenetic modifications in rice. PMID:31262943
Sequence-based GWAS, network and pathway analyses reveal genes co-associated with milk cheese-making properties and milk composition in Montbéliarde cows. PMID:31262251
MassComp, a lossless compressor for mass spectrometry data. PMID:31262247
N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer. PMID:31260412
The origin, diversification and adaptation of a major mangrove clade (Rhizophoreae) revealed by whole-genome sequencing. PMID:31258950
SynMyco transposon: engineering transposon vectors for efficient transformation of minimal genomes. PMID:31257417
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons. PMID:31257103
lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA. PMID:31256989
Identification of T-DNA Insertion Site and Flanking Sequence of a Genetically Modified Maize Event IE09S034 Using Next-Generation Sequencing Technology. PMID:31256331
Detection of mutational patterns in cell-free DNA of colorectal cancer by custom amplicon sequencing. PMID:31254442
A high-throughput BAC end analysis protocol (BAC-anchor) for profiling genome assembly and physical mapping. PMID:31254434
Multimapping confounds ribosome profiling analysis: A case-study of the Hsp90 molecular chaperone. PMID:31254414
Intracellular Zn2+ transients modulate global gene expression in dissociated rat hippocampal neurons. PMID:31253848
A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS). PMID:31253799
Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness. PMID:31253791
Unexpected host dependency of Antarctic Nanohaloarchaeota. PMID:31253704
Evolving neoantigen profiles in colorectal cancers with DNA repair defects. PMID:31253177
Effect of prematurity on genome wide methylation in the placenta. PMID:31253109
Odyssey: a semi-automated pipeline for phasing, imputation, and analysis of genome-wide genetic data. PMID:31253090
Polymorphic edge detection (PED): two efficient methods of polymorphism detection from next-generation sequencing data. PMID:31253084
Two Phages of the Genera Felixounavirus Subjected to 12 Hour Challenge on Salmonella Infantis Showed Distinct Genotypic and Phenotypic Changes. PMID:31252667
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. PMID:31251911
Ancient Hybridization and Adaptive Introgression of an Invadolysin Gene in Schistosome Parasites. PMID:31251352
Bioinformatic Methods and Bridging of Assay Results for Reliable Tumor Mutational Burden Assessment in Non-Small-Cell Lung Cancer. PMID:31250328
Effective identification of soybean candidate genes involved in resistance to soybean cyst nematode via direct whole genome re-sequencing of two segregating mutants. PMID:31250041
Genetic basis of species-specific genitalia reveals role in species diversification. PMID:31249868
De novo assembly of the goldfish (Carassius auratus) genome and the evolution of genes after whole-genome duplication. PMID:31249862
Whole exome sequencing of patients who resolved Crohn's disease and complex regional pain syndrome following treatment for paratuberculosis. PMID:31249631
The ENCODE Blacklist: Identification of Problematic Regions of the Genome. PMID:31249361
The Tomato Translational Landscape Revealed by Transcriptome Assembly and Ribosome Profiling. PMID:31248964
Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses. PMID:31248780
The Genome of the Steller Sea Lion (Eumetopias jubatus). PMID:31248052
Indel detection from Whole Genome Sequencing data and association with lipid metabolism in pigs. PMID:31246983
artMAP: A user-friendly tool for mapping ethyl methanesulfonate-induced mutations in Arabidopsis. PMID:31245783
Waterlogging affects plant morphology and the expression of key genes in tef (Eragrostis tef). PMID:31245721
Dark period transcriptomic and metabolic profiling of two diverse Eutrema salsugineum accessions. PMID:31245703
Evolution of Alternative Splicing in Eudicots. PMID:31244865
Mobilome of Brevibacterium aurantiacum Sheds Light on Its Genetic Diversity and Its Adaptation to Smear-Ripened Cheeses. PMID:31244798
Comparative Genomics of Wild Bee and Flower Isolated Lactobacillus Reveals Potential Adaptation to the Bee Host. PMID:31243442
Gene expression across mammalian organ development. PMID:31243369
Developmental dynamics of lncRNAs across mammalian organs and species. PMID:31243368
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation. PMID:31243293
Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia. PMID:31243274
Grapevine comparative early transcriptomic profiling suggests that Flavescence dorée phytoplasma represses plant responses induced by vector feeding in susceptible varieties. PMID:31242866
Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar. PMID:31242858
Tandem 13-Lipoxygenase Genes in a Cluster Confers Yellow-Green Leaf in Cucumber. PMID:31242619
Transcriptome characterization and differentially expressed genes under flooding and drought stress in the biomass grasses Phalaris arundinacea and Dactylis glomerata. PMID:31241131
CoGe LoadExp+: A web-based suite that integrates next-generation sequencing data analysis workflows and visualization. PMID:31240274
The poplar pangenome provides insights into the evolutionary history of the genus. PMID:31240253
Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors. PMID:31240244
3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome. PMID:31240104
An integrated prediction model of recurrence in endometrial endometrioid cancers. PMID:31239780
Genome-wide analysis of genetic variations between dominant and recessive NILs of glanded and glandless cottons. PMID:31239518
Genome-Wide Profiling of Polyadenylation Events in Maize Using High-Throughput Transcriptomic Sequences. PMID:31239292
DNA methylome and transcriptome alterations and cancer prevention by triterpenoid ursolic acid in UVB-induced skin tumor in mice. PMID:31237383
Circulating T cell-monocyte complexes are markers of immune perturbations. PMID:31237234
A PEX5 missense allele preferentially disrupts PTS1 cargo import into Arabidopsis peroxisomes. PMID:31236542
Comparing Pool-seq, Rapture, and GBS genotyping for inferring weak population structure: The American lobster (Homarus americanus) as a case study. PMID:31236247
The genetic basis of 3-hydroxypropanoate metabolism in Cupriavidus necator H16. PMID:31236137
Moving Just Enough Deep Sequencing Data to Get the Job Done. PMID:31236009
Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism. PMID:31235964
Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns. PMID:31235656
The Impact of TCR Signal Strength on Resident Memory T Cell Formation during Influenza Virus Infection. PMID:31235552
Evaluating 18s-rRNA LAMP and selective whole genome amplification (sWGA) assay in detecting asymptomatic Plasmodium falciparum infections in blood donors. PMID:31234871
Master regulator analysis of paragangliomas carrying SDHx, VHL, or MAML3 genetic alterations. PMID:31234811
Septo-optic dysplasia caused by a novel FLNA splice site mutation: a case report. PMID:31234783
Dissecting the Genetic Architecture of Seed Protein and Oil Content in Soybean from the Yangtze and Huaihe River Valleys Using Multi-Locus Genome-Wide Association Studies. PMID:31234445
Interrogation of Phenotypic Plasticity between Epithelial and Mesenchymal States in Breast Cancer. PMID:31234417
Developmental atlas of the RNA editome in Sus scrofa skeletal muscle. PMID:31231762
Genetic and Phenotypic Characterization of the Etiological Agent of Canine Orchiepididymitis Smooth Brucella sp. BCCN84.3. PMID:31231665
Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing. PMID:31231536
Beyond the Big Five: Investigating Myostatin Structure, Polymorphism and Expression in Camelus dromedarius. PMID:31231423
Genome Sequence Analysis Reveals Selection Signatures in Endangered Trypanotolerant West African Muturu Cattle. PMID:31231417
Assembly and Characterization of a Pathogen Strain Collection for Produce Safety Applications: Pre-growth Conditions Have a Larger Effect on Peroxyacetic Acid Tolerance Than Strain Diversity. PMID:31231329
Immediate Dosage Compensation Is Triggered by the Deletion of Y-Linked Genes in Silene latifolia. PMID:31231053
A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity. PMID:31231045
The Genomics of Arthrogryposis, a Complex Trait: Candidate Genes and Further Evidence for Oligogenic Inheritance. PMID:31230720
Atlas of Subcellular RNA Localization Revealed by APEX-Seq. PMID:31230715
Clinicopathological characteristics and molecular abnormalities of primary grade 2 neuroendocrine tumors of the cervix. PMID:31228945
Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea. PMID:31227770
A Rapid and Accurate MinION-Based Workflow for Tracking Species Biodiversity in the Field. PMID:31226847
Aspergillus flavus NRRL 35739, a Poor Biocontrol Agent, May Have Increased Relative Expression of Stress Response Genes. PMID:31226781
Deep sequencing of 2009 influenza A/H1N1 virus isolated from volunteer human challenge study participants and natural infections. PMID:31226666
Modeling RNA-Binding Protein Specificity In Vivo by Precisely Registering Protein-RNA Crosslink Sites. PMID:31226278
SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina. PMID:31226208
The nucleosome acidic patch directly interacts with subunits of the Paf1 and FACT complexes and controls chromatin architecture in vivo. PMID:31226204
Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1. PMID:31225797
An MLST approach to support tracking of plasmids carrying OXA-48-like carbapenemase. PMID:31225613
Detection of a novel locus involved in non-seed-shattering behaviour of Japonica rice cultivar, Oryzasativa 'Nipponbare'. PMID:31222437
Duphold: scalable, depth-based annotation and curation of high-confidence structural variant calls. PMID:31222198
High-Resolution Copy Number Patterns From Clinically Relevant FFPE Material. PMID:31222134
Description of strongly heat-inducible heat shock protein 70 transcripts from Baikal endemic amphipods. PMID:31222132
Effect of heritable symbionts on maternally-derived embryo transcripts. PMID:31222094
Whole genome resequencing data for three rockfish species of Sebastes. PMID:31222011
Hybridization between two high Arctic cetaceans confirmed by genomic analysis. PMID:31221994
RST1 Is a FREE1 Suppressor That Negatively Regulates Vacuolar Trafficking in Arabidopsis. PMID:31221737
Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3. PMID:31221665
Bone morphology is regulated modularly by global and regional genetic programs. PMID:31221640
DNMT3B shapes the mCA landscape and regulates mCG for promoter bivalency in human embryonic stem cells. PMID:31219573
Effects of somatic alterations at pathway level are more mechanism-explanatory and clinically applicable to quantity of liver metastases of colorectal cancer. PMID:31219228
PREFACE: In silico pipeline for accurate cell-free fetal DNA fraction prediction. PMID:31219182
piRNA-guided co-transcriptional silencing coopts nuclear export factors. PMID:31219034
An ultra-high-density genetic map provides insights into genome synteny, recombination landscape and taproot skin colour in radish (Raphanus sativus L.). PMID:31218798
GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice. PMID:31218575
First Estimation of the Spontaneous Mutation Rate in Diatoms. PMID:31218358
The Genomic Origins of Small Mitochondrial RNAs: Are They Transcribed by the Mitochondrial DNA or by Mitochondrial Pseudogenes within the Nucleus (NUMTs)? PMID:31218347
Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes. PMID:31217899
Noncoding deletions reveal a gene that is critical for intestinal function. PMID:31217582
Severe influenza pneumonitis in children with inherited TLR3 deficiency. PMID:31217193
ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells. PMID:31217031
Genome-wide Integrative Analysis of Zika-Virus-Infected Neuronal Stem Cells Reveals Roles for MicroRNAs in Cell Cycle and Stemness. PMID:31216479
Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells. PMID:31216472
Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells. PMID:31216471
Rational Reprogramming of Cellular States by Combinatorial Perturbation. PMID:31216470
Somatic mutation that affects transcription factor binding upstream of CD55 in the temporal cortex of a late-onset Alzheimer disease patient. PMID:31216356
p73 regulates epidermal wound healing and induced keratinocyte programming. PMID:31216312
Identification of two molecular subtypes in canine mast cell tumours through gene expression profiling. PMID:31216299
Interplay between small RNA pathways shapes chromatin landscapes in C. elegans. PMID:31216042
SMARTer single cell total RNA sequencing. PMID:31216024
Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2. PMID:31215866
Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans. PMID:31215115
Whole-Genome Analysis of Halomonas sp. Soap Lake #7 Reveals It Possesses Putative Mrp Antiporter Operon Groups 1 and 2. PMID:31214690
Simultaneous TE Analysis of 19 Heliconiine Butterflies Yields Novel Insights into Rapid TE-Based Genome Diversification and Multiple SINE Births and Deaths. PMID:31214686
Wavelet-Based Genomic Signal Processing for Centromere Identification and Hypothesis Generation. PMID:31214244
Effects of Host, Sample, and in vitro Culture on Genomic Diversity of Pathogenic Mycobacteria. PMID:31214242
Assessment of low-coverage nanopore long read sequencing for SNP genotyping in doubled haploid canola (Brassica napus L.). PMID:31213642
Genome-wide CRISPR screen identifies suppressors of endoplasmic reticulum stress-induced apoptosis. PMID:31213543
Forward Genetic Screen for Caenorhabditis elegans Mutants with a Shortened Locomotor Healthspan. PMID:31213517
The effects of the neonicotinoid imidacloprid on gene expression and DNA methylation in the buff-tailed bumblebee Bombus terrestris. PMID:31213186
SpinachBase: a central portal for spinach genomics. PMID:31211398
Data on the polymorphic sites in the chloroplast genomes of the sunflower alloplasmic CMS lines. PMID:31211212
Quantitative evidence for early metastatic seeding in colorectal cancer. PMID:31209394
Genome sequencing analysis identifies Epstein-Barr virus subtypes associated with high risk of nasopharyngeal carcinoma. PMID:31209392
Myc and Dnmt1 impede the pluripotent to totipotent state transition in embryonic stem cells. PMID:31209294
Analysis of whole Y-chromosome sequences reveals the Japanese population history in the Jomon period. PMID:31209235
Polar bear evolution is marked by rapid changes in gene copy number in response to dietary shift. PMID:31209046
Transcriptome-based molecular systematics: Rhodnius montenegrensis (Triatominae) and its position within the Rhodnius prolixus-Rhodnius robustus cryptic-species complex. PMID:31208458
Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression. PMID:31208332
Novel subpopulations in date palm (Phoenix dactylifera) identified by population-wide organellar genome sequencing. PMID:31208317
Analysis of allele-specific expression using RNA-seq of the Korean native pig and Landrace reciprocal cross. PMID:31208168
TOX is a critical regulator of tumour-specific T cell differentiation. PMID:31207604
Pathogenic and likely pathogenic variants in PALB2, CHEK2, and other known breast cancer susceptibility genes among 1054 BRCA-negative Hispanics with breast cancer. PMID:31206626
Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evolution. PMID:31206013
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. PMID:31204176
Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver. PMID:31204013
RINT1 Bi-allelic Variations Cause Infantile-Onset Recurrent Acute Liver Failure and Skeletal Abnormalities. PMID:31204009
Adaptive Evolution Patterns in the Pacific Oyster Crassostrea gigas. PMID:31203476
Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia). PMID:31203412
Global Quantitative Mapping of Enhancers in Rice by STARR-seq. PMID:31201999
Chromatin interaction maps reveal genetic regulation for quantitative traits in maize. PMID:31201335
Genomic signatures of heterokaryosis in the oomycete pathogen Bremia lactucae. PMID:31201315
High-coverage, long-read sequencing of Han Chinese trio reference samples. PMID:31201313
isqg: A Binary Framework for in Silico Quantitative Genetics. PMID:31201204
Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex. PMID:31201089
Characterization of genes required for both Rpg1 and rpg4-mediated wheat stem rust resistance in barley. PMID:31200635
Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock. PMID:31199242
mRNA expression data in breast cancers before and after consumption of walnut by women. PMID:31198831
Emergence of plasmid stability under non-selective conditions maintains antibiotic resistance. PMID:31197163
Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection. PMID:31197149
RNA-Seq analysis of soft rush (Juncus effusus): transcriptome sequencing, de novo assembly, annotation, and polymorphism identification. PMID:31195970
Evolution of asexual Daphnia pulex in Japan: variations and covariations of the digestive, morphological and life history traits. PMID:31195967
Profiling the genome-wide landscape of tandem repeat expansions. PMID:31194863
Fall armyworm (Spodoptera frugiperda Smith) feeding elicits differential defense responses in upland and lowland switchgrass. PMID:31194847
A key role for sex chromosomes in the regulation of parthenogenesis in the brown alga Ectocarpus. PMID:31194744
A Whole-genome Sequencing Analysis of Neisseria gonorrhoeae Isolates in China: An Observational Study. PMID:31193648
Evolutionary transcriptomics reveals the origins of olives and the genomic changes associated with their domestication. PMID:31192486
Phenotypic Overlap of Roberts and Baller-Gerold Syndromes in Two Patients With Craniosynostosis, Limb Reductions, and ESCO2 Mutations. PMID:31192177
A Quasi-Domesticate Relic Hybrid Population of Saccharomyces cerevisiae × S. paradoxus Adapted to Olive Brine. PMID:31191600
Co-Occurrence of Leber Congenital Amaurosis and Meckel Syndrome Type 1 in a Fetus: Is There a Lesson to Be Learned? PMID:31191208
Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. PMID:31189107
ZIC3 Controls the Transition from Naive to Primed Pluripotency. PMID:31189106
Whole genome SNPs discovery in Nero Siciliano pig. PMID:31188930
Bacterial Single Cell Whole Transcriptome Amplification in Microfluidic Platform Shows Putative Gene Expression Heterogeneity. PMID:31188565
Genome-wide polymorphisms from RNA sequencing assembly of leaf transcripts facilitate phylogenetic analysis and molecular marker development in wild einkorn wheat. PMID:31187273
Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease. PMID:31186947
Genomic and phenotypic consequences of two independent secondary contact zones between allopatric lineages of the anadromous ice goby Leucopsarion petersii. PMID:31186532
Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression. PMID:31186331
Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits. PMID:31186305
Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome. PMID:31186302
Machine-learning to stratify diabetic patients using novel cardiac biomarkers and integrative genomics. PMID:31185988
A genomic resource derived from the integration of genome sequences, expressed transcripts and genetic markers in ramie. PMID:31185891
GenPipes: an open-source framework for distributed and scalable genomic analyses. PMID:31185495
Putative novel cps loci in a large global collection of pneumococci. PMID:31184299
Historical contingency shapes adaptive radiation in Antarctic fishes. PMID:31182814
Orb-weaving spider Araneus ventricosus genome elucidates the spidroin gene catalogue. PMID:31182776
Genomic erosion and extensive horizontal gene transfer in gut-associated Acetobacteraceae. PMID:31182035
Novel de novo frameshift variant in the ASXL3 gene in a child with microcephaly and global developmental delay. PMID:31180560
Whole-Exome Sequencing Enables the Diagnosis of Variant-Type Xeroderma Pigmentosum. PMID:31178899
Diagnostic Yields of Trio-WES Accompanied by CNVseq for Rare Neurodevelopmental Disorders. PMID:31178897
A First Y-Chromosomal Haplotype Network to Investigate Male-Driven Population Dynamics in Domestic and Wild Bactrian Camels. PMID:31178891
The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes. PMID:31178404
3' Uridylation Confers miRNAs with Non-canonical Target Repertoires. PMID:31178353
Comprehensive Integration of Single-Cell Data. PMID:31178118
GRID-seq for comprehensive analysis of global RNA-chromatin interactions. PMID:31175345
An asymmetric allelic interaction drives allele transmission bias in interspecific rice hybrids. PMID:31175302
Adaptive Responses of Shewanella decolorationis to Toxic Organic Extracellular Electron Acceptor Azo Dyes in Anaerobic Respiration. PMID:31175185
Small, but surprisingly repetitive genomes: transposon expansion and not polyploidy has driven a doubling in genome size in a metazoan species complex. PMID:31174483
Genome-wide profiling of the alternative splicing provides insights into development in Plutella xylostella. PMID:31174467
Whole exome sequencing and methylation‑specific multiplex ligation‑dependent probe amplification applied to identify Angelman syndrome due to paternal uniparental disomy in two unrelated patients. PMID:31173236
Gene Family Evolution in the Pea Aphid Based on Chromosome-Level Genome Assembly. PMID:31173104
Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations. PMID:31173078
Population Genomic Signatures of Genetic Structure and Environmental Selection in the Catadromous Roughskin Sculpin Trachidermus fasciatus. PMID:31173074
Genome plasticity in Candida albicans is driven by long repeat sequences. PMID:31172944
QTL-seq identifies cooked grain elongation QTLs near soluble starch synthase and starch branching enzymes in rice (Oryza sativa L.). PMID:31171826
A machine-learning approach for accurate detection of copy number variants from exome sequencing. PMID:31171634
Complete Genome Sequence of Halomonas sulfidaeris Strain Esulfide1 Isolated from a Metal Sulfide Rock at a Depth of 2,200 Meters, Obtained Using Nanopore Sequencing. PMID:31171615
hg19KIndel: ethnicity normalized human reference genome. PMID:31170919
A comparative analysis of the transcriptome profiles of liver and muscle tissue in pigs divergent for feed efficiency. PMID:31170913
Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PMID:31170154
An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice. PMID:31169497
Combining next-generation sequencing and progeny testing for rapid identification of induced recessive and dominant mutations in maize M2 individuals. PMID:31169333
Effect of ethanol supplementation on the transcriptional landscape of bionanocellulose producer Komagataeibacter xylinus E25. PMID:31168651
Real-Time PCR Assay for Differentiation of Typhoidal and Nontyphoidal Salmonella. PMID:31167843
Single and Multi-trait GWAS Identify Genetic Factors Associated with Production Traits in Common Bean Under Abiotic Stress Environments. PMID:31167806
GRASP2: fast and memory-efficient gene-centric assembly and homolog search for metagenomic sequencing data. PMID:31167633
Genomic Evidence of Recombination in the Basidiomycete Wallemia mellicola. PMID:31167502
RNASeq Analysis of Aedes albopictus Mosquito Midguts after Chikungunya Virus Infection. PMID:31167461
Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability. PMID:31167142
Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation. PMID:31167141
Parthenogenesis in a captive Asian water dragon (Physignathus cocincinus) identified with novel microsatellites. PMID:31166974
Whole-genome sequencing based on formalin-fixed paraffin-embedded endomyocardial biopsies for genetic studies on outcomes after heart transplantation. PMID:31166960
Genome-wide association study identified novel candidate loci affecting wood formation in Norway spruce. PMID:31166032
SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis. PMID:31165730
Comparison Between Flat and Round Peaches, Genomic Evidences of Heterozygosity Events. PMID:31164893
An analysis of large structural variation in global Plasmodium falciparum isolates identifies a novel duplication of the chloroquine resistance associated gene. PMID:31164664
Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation. PMID:31164154
Copy number determination of the gene for the human pancreatic polypeptide receptor NPY4R using read depth analysis and droplet digital PCR. PMID:31164119
Deep expression analysis reveals distinct cold-response strategies in rubber tree (Hevea brasiliensis). PMID:31164105
The diversity, evolution and ecology of Salmonella in venomous snakes. PMID:31163033
Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community. PMID:31162049
Habitat preference modulates trans-oceanic dispersal in a terrestrial vertebrate. PMID:31161911
Mind the gap: resources required to receive, process and interpret research-returned whole genome data. PMID:31161416
Evidence for frequency-dependent selection maintaining polymorphism in the Batesian mimic Papilio polytes in multiple islands in the Ryukyus, Japan. PMID:31161014
Differential gene expression in relation to mating system in Peromyscine rodents. PMID:31161013
Sequence capture using AFLP-generated baits: A cost-effective method for high-throughput phylogenetic and phylogeographic analysis. PMID:31161009
Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew. PMID:31160924
Comparative Subsequence Sets Analysis (CoSSA) is a robust approach to identify haplotype specific SNPs; mapping and pedigree analysis of a potato wart disease resistance gene Sen3. PMID:31160919
Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. PMID:31160784
Gene Expression analysis associated with salt stress in a reciprocally crossed rice population. PMID:31160691
Genome-Wide DNA from Degraded Petrous Bones and the Assessment of Sex and Probable Geographic Origins of Forensic Cases. PMID:31160682
The LL-100 panel: 100 cell lines for blood cancer studies. PMID:31160637
Genomic characterization of a well-differentiated grade 3 pancreatic neuroendocrine tumor. PMID:31160355
Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei. PMID:31160283
NG-meta-profiler: fast processing of metagenomes using NGLess, a domain-specific language. PMID:31159881
Haplotype-aware diplotyping from noisy long reads. PMID:31159868
From reference genomes to population genomics: comparing three reference-aligned reduced-representation sequencing pipelines in two wildlife species. PMID:31159724
A comparison of three programming languages for a full-fledged next-generation sequencing tool. PMID:31159721
RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes. PMID:31158233
Computational Analysis of AmpSeq Data for Targeted, High-Throughput Genotyping of Amplicons. PMID:31156670
Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine. PMID:31156619
Predictability in the evolution of Orthopteran cardenolide insensitivity. PMID:31154978
Identification of quantitative trait loci associated with flowering time in perilla using genotyping-by-sequencing. PMID:31152338
Generic Repeat Finder: A High-Sensitivity Tool for Genome-Wide De Novo Repeat Detection. PMID:31152127
Identification of Loci Controlling the Dwarfism Trait in the White Sailfin Molly (Poecilia latipinna) Using Genome-Wide Association Studies Based on Genotyping-By-Sequencing. PMID:31151300
Multiple rare and common variants in APOB gene locus associated with oxidatively modified low-density lipoprotein levels. PMID:31150472
Relating Clans Ao and Aisin Gioro from northeast China by whole Y-chromosome sequencing. PMID:31148597
DNA methylation patterns in human iPSC-derived sensory neuronal differentiation. PMID:31148524
Analysis of the Chromosomal Localization of Yeast SMC Complexes by Chromatin Immunoprecipitation. PMID:31147914
Molecular Characterization of a Long-Term Survivor Double Metastatic Non-Small Cell Lung Cancer and Pancreatic Ductal Adenocarcinoma Treated with Gefitinib in Combination with Gemcitabine Plus Nab-Paclitaxel and mFOLFOX6 as First and Second Line Therapy. PMID:31146476
New steps in mucilage biosynthesis revealed by analysis of the transcriptome of the UDP-rhamnose/UDP-galactose transporter 2 mutant. PMID:31145803
Whole genome sequence of Vibrio cholerae directly from dried spotted filter paper. PMID:31145741
Population genomics of an outbreak of the potato late blight pathogen, Phytophthora infestans, reveals both clonality and high genotypic diversity. PMID:31145530
Deregulated expression of NKL homeobox genes in T-cell lymphomas. PMID:31143370
Comparative Analysis of Tools and Approaches for Source Tracking Listeria monocytogenes in a Food Facility Using Whole-Genome Sequence Data. PMID:31143162
Honey Bee Parasitic Mite Contains the Sensilla-Rich Sensory Organ on the Foreleg Tarsus Expressing Ionotropic Receptors With Conserved Functions. PMID:31143129
The association of germline variants with chronic lymphocytic leukemia outcome suggests the implication of novel genes and pathways in clinical evolution. PMID:31142279
DisV-HPV16, versatile and powerful software to detect HPV in RNA sequencing data. PMID:31142265
The Red Fox Y-Chromosome in Comparative Context. PMID:31142040
Evaluation of Sequencing Library Preparation Protocols for Viral Metagenomic Analysis from Pristine Aquifer Groundwaters. PMID:31141902
The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer. PMID:31141692
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration. PMID:31140325
Phylogenomic Approaches to DNA Barcoding of Herbal Medicines: Developing Clade-Specific Diagnostic Characters for Berberis. PMID:31139202
Improved TGIRT-seq methods for comprehensive transcriptome profiling with decreased adapter dimer formation and bias correction. PMID:31138886
RNA-seq analysis and fluorescence imaging of melon powdery mildew disease reveal an orchestrated reprogramming of host physiology. PMID:31138852
Interspecies conservation of organisation and function between nonhomologous regional centromeres. PMID:31138803
Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production. PMID:31138751
The PLATZ Transcription Factor GL6 Affects Grain Length and Number in Rice. PMID:31138620
Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles. PMID:31138172
mRNA profiling reveals significant transcriptional differences between a multipotent progenitor and its differentiated sister. PMID:31138122
Transcriptome Analysis of Gene Families Involved in Chemosensory Function in Spodoptera littoralis (Lepidoptera: Noctuidae). PMID:31138111
Social group signatures in hummingbird displays provide evidence of co-occurrence of vocal and visual learning. PMID:31138067
Conservation Genomics in the Sagebrush Sea: Population Divergence, Demographic History, and Local Adaptation in Sage-Grouse (Centrocercus spp.). PMID:31135036
Recent Secondary Contacts, Linked Selection, and Variable Recombination Rates Shape Genomic Diversity in the Model Species Anolis carolinensis. PMID:31134281
ExpansionHunter: a sequence-graph-based tool to analyze variation in short tandem repeat regions. PMID:31134279
Whole Genome Sequencing and Comparative Genomic Analysis Reveal Allelic Variations Unique to a Purple Colored Rice Landrace (Oryza sativa ssp. indica cv. Purpleputtu). PMID:31134103
Comparative Genomics Reveals the High Copy Number Variation of a Retro Transposon in Different Magnaporthe Isolates. PMID:31134015
Clinical utility of custom-designed NGS panel testing in pediatric tumors. PMID:31133068
A new reference genome for Sorghum bicolor reveals high levels of sequence similarity between sweet and grain genotypes: implications for the genetics of sugar metabolism. PMID:31133004
Rare variant phasing using paired tumor:normal sequence data. PMID:31132991
Attenuation of Bluetongue Virus (BTV) in an in ovo Model Is Related to the Changes of Viral Genetic Diversity of Cell-Culture Passaged BTV. PMID:31130699
Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. PMID:31130414
Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes. PMID:31130341
VCF-Server: A web-based visualization tool for high-throughput variant data mining and management. PMID:31127704
High efficiency error suppression for accurate detection of low-frequency variants. PMID:31127310
Microhomologies are prevalent at Cas9-induced larger deletions. PMID:31127293
Acute depletion of CTCF directly affects MYC regulation through loss of enhancer-promoter looping. PMID:31127282
A post-transcriptional respiratome regulon in trypanosomes. PMID:31127277
Molecular mechanisms of temperature acclimation and adaptation in marine diatoms. PMID:31127177
Y-chromosomal connection between Hungarians and geographically distant populations of the Ural Mountain region and West Siberia. PMID:31127140
Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification. PMID:31127120
Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel. PMID:31127048
Nutrient-sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock. PMID:31126958
Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data. PMID:31126321
Transcriptional analysis of renal dopamine-mediated Na+ homeostasis response to environmental salinity stress in Scatophagus argus. PMID:31126236
Cytogenetic and molecular diagnosis of Fanconi anemia revealed two hidden phenotypes: Disorder of sex development and cerebro-oculo-facio-skeletal syndrome. PMID:31124294
Ancient DNA from mastics solidifies connection between material culture and genetics of mesolithic hunter-gatherers in Scandinavia. PMID:31123709
Whole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins. PMID:31123420
The AvrPm3-Pm3 effector-NLR interactions control both race-specific resistance and host-specificity of cereal mildews on wheat. PMID:31123263
Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans. PMID:31123081
Exome-wide search and functional annotation of genes associated in patients with severe tick-borne encephalitis in a Russian population. PMID:31122248
Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species. PMID:31121116
Expression levels of inositol phosphorylceramide synthase modulate plant responses to biotic and abiotic stress in Arabidopsis thaliana. PMID:31120963
Use of near-isogenic lines to precisely map and validate a major QTL for grain weight on chromosome 4AL in bread wheat (Triticum aestivum L.). PMID:31119311
Uncultured Nitrospina-like species are major nitrite oxidizing bacteria in oxygen minimum zones. PMID:31118472
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks. PMID:31118277
Microfluidics-Based Enrichment and Whole-Genome Amplification Enable Strain-Level Resolution for Airway Metagenomics. PMID:31117025
Circuit diversification in a biofilm regulatory network. PMID:31116789
MetaQUBIC: a computational pipeline for gene-level functional profiling of metagenome and metatranscriptome. PMID:31116375
GATA4 screening in Iranian patients of various ethnicities affected with congenital heart disease: Co-occurrence of a novel de novo translocation (5;7) and a likely pathogenic heterozygous GATA4 mutation in a family with autosomal dominant congenital heart disease. PMID:31115957
De novo genome assembly of the cichlid fish Astatotilapia latifasciata reveals a higher level of genomic polymorphism and genes related to B chromosomes. PMID:31115663
FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences. PMID:31114866
Parallel Molecular Evolution in Pathways, Genes, and Sites in High-Elevation Hummingbirds Revealed by Comparative Transcriptomics. PMID:31114863
The Role of Chromatin Accessibility in cis-Regulatory Evolution. PMID:31114856
The Genomic Complexity of a Large Inversion in Great Tits. PMID:31114855
Transcriptional profiling of coaggregation interactions between Streptococcus gordonii and Veillonella parvula by Dual RNA-Seq. PMID:31113978
Metabolic Remodeling during Biofilm Development of Bacillus subtilis. PMID:31113899
Early Sex-Chromosome Evolution in the Diploid Dioecious Plant Mercurialis annua. PMID:31113811
Genetic diversity and population structure of Ethiopian Capsicum germplasms. PMID:31112575
Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts. PMID:31112549
Fifty Aureobasidium pullulans genomes reveal a recombining polyextremotolerant generalist. PMID:31112354
Klf4 Promotes Dentinogenesis and Odontoblastic Differentiation via Modulation of TGF-β Signaling Pathway and Interaction With Histone Acetylation. PMID:31112333
Identification of a de novo FOXP1 mutation and incidental discovery of inherited genetic variants contributing to a case of autism spectrum disorder and epilepsy. PMID:31111659
Characterization of introgression from the teosinte Zea mays ssp. mexicana to Mexican highland maize. PMID:31110920
Mutational Landscape of Spontaneous Base Substitutions and Small Indels in Experimental Caenorhabditis elegans Populations of Differing Size. PMID:31110155
Molecular characterization of Brucella species from Zimbabwe. PMID:31107864
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198. PMID:31107206
Shared genomic outliers across two divergent population clusters of a highly threatened seagrass. PMID:31106053
Whole-Genome Sequencing of the Opportunistic Yeast Pathogen Candida inconspicua Uncovers Its Hybrid Origin. PMID:31105748
Nutritional Heterogeneity Among Aspergillus fumigatus Strains Has Consequences for Virulence in a Strain- and Host-Dependent Manner. PMID:31105662
Genome analysis provides insight about pathogenesis of Indian strains of Rhizoctonia solani in rice. PMID:31102065
ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma. PMID:31101826
Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates. PMID:31100356
Ceftazidime-Avibactam in Combination With Fosfomycin: A Novel Therapeutic Strategy Against Multidrug-Resistant Pseudomonas aeruginosa. PMID:31099835
Use of whole genome sequencing in surveillance for antimicrobial-resistant Shigella sonnei infections acquired from domestic and international sources. PMID:31099740
Cram-JS: reference-based decompression in node and the browser. PMID:31099383
SETD2, GIGYF2, FGFR3, BCR, KMT2C, and TSC2 as candidate genes for differentiating multilocular cystic renal neoplasm of low malignant potential from clear cell renal cell carcinoma with cystic change. PMID:31098421
A missense mutation in MYO7A is associated with bilateral deafness and vestibular dysfunction in the Doberman pinscher breed. PMID:31097876
Draft genome of the big-headed turtle Platysternon megacephalum. PMID:31097710
Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers. PMID:31097695
Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth. PMID:31097545
Long-read sequencing reveals a 4.4 kb tandem repeat region in the mitogenome of Echinococcus granulosus (sensu stricto) genotype G1. PMID:31097022
NeoMutate: an ensemble machine learning framework for the prediction of somatic mutations in cancer. PMID:31096972
Molecular identification of late and terminal Pleistocene Equus ovodovi from northeastern China. PMID:31095634
Total synthesis of Escherichia coli with a recoded genome. PMID:31092918
Inferring the history of surname Ye based on Y chromosome high-resolution genotyping and sequencing data. PMID:31092888
A Non-Dicer RNase III and Four Other Novel Factors Required for RNAi-Mediated Transposon Suppression in the Human Pathogenic Yeast Cryptococcus neoformans. PMID:31092606
The Paf1 Complex Broadly Impacts the Transcriptome of Saccharomyces cerevisiae. PMID:31092540
Monitoring dynamic cytotoxic chemotherapy response in castration-resistant prostate cancer using plasma cell-free DNA (cfDNA). PMID:31092276
Accurate sequence variant genotyping in cattle using variation-aware genome graphs. PMID:31092189
Genetic diversity of avocado (Persea americana Mill.) germplasm using pooled sequencing. PMID:31092188
Acetate Promotes T Cell Effector Function during Glucose Restriction. PMID:31091446
Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype. PMID:31091232
Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania. PMID:31091230
Ultra-deep, long-read nanopore sequencing of mock microbial community standards. PMID:31089679
Multiple Lineages of Dengue Virus Serotype 2 Cosmopolitan Genotype Caused a Local Dengue Outbreak in Hangzhou, Zhejiang Province, China, in 2017. PMID:31089152
Restriction of Cellular Plasticity of Differentiated Cells Mediated by Chromatin Modifiers, Transcription Factors and Protein Kinases. PMID:31088904
Joint Estimates of Heterozygosity and Runs of Homozygosity for Modern and Ancient Samples. PMID:31088861
Identification of genetic association between cardiorespiratory fitness and the trainability genes in childhood acute lymphoblastic leukemia survivors. PMID:31088516
Transcriptome assembly for a colour-polymorphic grasshopper (Gomphocerus sibiricus) with a very large genome size. PMID:31088494
A high-density genetic map and QTL mapping of leaf traits and glucosinolates in Barbarea vulgaris. PMID:31088355
Characterization of phytohormone and transcriptome reprogramming profiles during maize early kernel development. PMID:31088353
Next-generation sequencing identified genomic region and diagnostic markers for resistance to bacterial wilt on chromosome B02 in peanut (Arachis hypogaea L.). PMID:31087470
Genetic architecture and sex-specific selection govern modular, male-biased evolution of doublesex. PMID:31086812
Molecular identification of the causal locus for the petaloid phenotype in Daucus carota. PMID:31086497
Islands of retroelements are major components of Drosophila centromeres. PMID:31086362
Antimicrobial activity and carbohydrate metabolism in the bacterial metagenome of the soil-living invertebrate Folsomia candida. PMID:31086216
GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions. PMID:31086182
A Mutagenic Screen Identifies a TonB-Dependent Receptor Required for the Lanthanide Metal Switch in the Type I Methanotroph "Methylotuvimicrobium buryatense" 5GB1C. PMID:31085692
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia. PMID:31085557
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. PMID:31085178
Impaired insulin signaling in the B10.D2-Hc0 H2d H2-T18c/oSnJ mouse model of complement factor 5 deficiency. PMID:31084499
Recent establishment of tick-borne encephalitis foci with distinct viral lineages in the Helsinki area, Finland. PMID:31084456
Genetic Variation for Seed Metabolite Levels in Brachypodium distachyon. PMID:31083584
Plant-necrotroph co-transcriptome networks illuminate a metabolic battlefield. PMID:31081752
Snf2 controls pulcherriminic acid biosynthesis and antifungal activity of the biocontrol yeast Metschnikowia pulcherrima. PMID:31081214
Pigment Nephropathy in a Patient With PYGM Gene Mutation. PMID:31080931
Genomic changes in the biological control agent Cryptolaemus montrouzieri associated with introduction. PMID:31080510
Deciphering the patterns of genetic admixture and diversity in southern European cattle using genome-wide SNPs. PMID:31080507
Patterns of cross-resistance and collateral sensitivity between clinical antibiotics and natural antimicrobials. PMID:31080502
Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers. PMID:31080136
Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity. PMID:31080084
The Arrival of Siberian Ancestry Connecting the Eastern Baltic to Uralic Speakers further East. PMID:31080083
Host Genome Variation is Associated with Neurocognitive Outcome in Survivors of Pediatric Medulloblastoma. PMID:31078964
Evolution of the gut microbiome following acute HIV-1 infection. PMID:31078141
The Legacy of Sexual Ancestors in Phenotypic Variability, Gene Expression, and Homoeolog Regulation of Asexual Hybrids and Polyploids. PMID:31077330
Fitness Landscape of the Fission Yeast Genome. PMID:31077324
Enhancement of cellulase production in Trichoderma reesei RUT-C30 by comparative genomic screening. PMID:31077201
Development of Three Sets of High-Throughput Genotyped Rice Chromosome Segment Substitution Lines and QTL Mapping for Eleven Traits. PMID:31076960
Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea. PMID:31076507
The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria. PMID:31076285
A Premature Stop Codon in RAF1 Is the Priority Candidate Causative Mutation of the Inherited Chicken Wingless-2 Developmental Syndrome. PMID:31075853
Genomic DNA methylation distinguishes subtypes of human focal cortical dysplasia. PMID:31074842
Endogenous APOBEC3B Overexpression Constitutively Generates DNA Substitutions and Deletions in Myeloma Cells. PMID:31073151
An atypical pulmonary fibrosis is associated with co-inheritance of mutations in the calcium binding protein genes S100A3 and S100A13. PMID:31073086
ALG-1 Influences Accurate mRNA Splicing Patterns in the Caenorhabditis elegans Intestine and Body Muscle Tissues by Modulating Splicing Factor Activities. PMID:31073019
Comparative transcriptome analysis of trout skin pigment cells. PMID:31072301
Redondoviridae, a Family of Small, Circular DNA Viruses of the Human Oro-Respiratory Tract Associated with Periodontitis and Critical Illness. PMID:31071295
Return to the Sea, Get Huge, Beat Cancer: An Analysis of Cetacean Genomes Including an Assembly for the Humpback Whale (Megaptera novaeangliae). PMID:31070747
The lysosomal disease caused by mutant VPS33A. PMID:31070736
Mutation dynamics of CpG dinucleotides during a recent event of vertebrate diversification. PMID:31070073
Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation. PMID:31069274
Fungal acetylome comparative analysis identifies an essential role of acetylation in human fungal pathogen virulence. PMID:31069264
Whole Exome Sequencing of Cell-Free DNA for Early Lung Cancer: A Pilot Study to Differentiate Benign From Malignant CT-Detected Pulmonary Lesions. PMID:31069172
P-TEFb Regulates Transcriptional Activation in Non-coding RNA Genes. PMID:31068966
Lasy-Seq: a high-throughput library preparation method for RNA-Seq and its application in the analysis of plant responses to fluctuating temperatures. PMID:31068632
Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval. PMID:31068470
Whole-Genome Single-Nucleotide Polymorphism (SNP) Analysis Applied Directly to Stool for Genotyping Shiga Toxin-Producing Escherichia coli: an Advanced Molecular Detection Method for Foodborne Disease Surveillance and Outbreak Tracking. PMID:31068414
Helicobacter pylori Mutations Detected by Next-Generation Sequencing in Formalin-Fixed, Paraffin-Embedded Gastric Biopsy Specimens Are Associated with Treatment Failure. PMID:31068413
Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group. PMID:31068148
Mitochondrial genome and transcriptome analysis of five alloplasmic male-sterile lines in Brassica juncea. PMID:31068124
Composite Analysis of the Virome and Bacteriome of HIV/HPV Co-Infected Women Reveals Proxies for Immunodeficiency. PMID:31067713
Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells. PMID:31067469
Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer. PMID:31067463
Chromatin Decondensation by FOXP2 Promotes Human Neuron Maturation and Expression of Neurodevelopmental Disease Genes. PMID:31067457
CPGAVAS2, an integrated plastome sequence annotator and analyzer. PMID:31066451
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk. PMID:31064983
Authentic Modeling of Human Respiratory Virus Infection in Human Pluripotent Stem Cell-Derived Lung Organoids. PMID:31064833
Human contamination in bacterial genomes has created thousands of spurious proteins. PMID:31064768
Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines. PMID:31061680
L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control. PMID:31061493
A highly flexible and repeatable genotyping method for aquaculture studies based on target amplicon sequencing using next-generation sequencing technology. PMID:31061473
Unraveling ancestry, kinship, and violence in a Late Neolithic mass grave. PMID:31061125
Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis. PMID:31061095
BacTag - a pipeline for fast and accurate gene and allele typing in bacterial sequencing data based on database preprocessing. PMID:31060512
Characterization of a non-sexual population of Strongyloides stercoralis with hybrid 18S rDNA haplotypes in Guangxi, Southern China. PMID:31059500
Genomic Characterization of External Morphology Traits in Kelpies Does Not Support Common Ancestry with the Australian Dingo. PMID:31058880
Germline Predisposition and Copy Number Alteration in Pre-stage Lung Adenocarcinomas Presenting as Ground-Glass Nodules. PMID:31058088
Noonan Syndrome in South Africa: Clinical and Molecular Profiles. PMID:31057598
Phenotypic Plasticity of Staphylococcus aureus in Liquid Medium Containing Vancomycin. PMID:31057516
DeviaTE: Assembly-free analysis and visualization of mobile genetic element composition. PMID:31056858
Analysis of Subtelomeric REXTAL Assemblies Using QUAST. PMID:31056507
Maintenance of CTCF- and Transcription Factor-Mediated Interactions from the Gametes to the Early Mouse Embryo. PMID:31056445
High-resolution, strand-specific R-loop mapping via S9.6-based DNA-RNA immunoprecipitation and high-throughput sequencing. PMID:31053798
Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis. PMID:31053723
Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways. PMID:31053165
A Secreted RNA Binding Protein Forms RNA-Stabilizing Granules in the Honeybee Royal Jelly. PMID:31051140
Human Cytomegalovirus Genomes Sequenced Directly From Clinical Material: Variation, Multiple-Strain Infection, Recombination, and Gene Loss. PMID:31050742
Multiple-Strain Infections of Human Cytomegalovirus With High Genomic Diversity Are Common in Breast Milk From Human Immunodeficiency Virus-Infected Women in Zambia. PMID:31050737
A novel high-density grapevine (Vitis vinifera L.) integrated linkage map using GBS in a half-diallel population. PMID:31049634
Calling Variants in the Clinic: Informed Variant Calling Decisions Based on Biological, Clinical, and Laboratory Variables. PMID:31049166
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation. PMID:31048683
Draft Genome Sequence from a Putative New Genus and Species in the Family Methanoregulaceae Isolated from the Anoxic Basin of Lake Untersee in East Antarctica. PMID:31048378
Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction. PMID:31047860
Development of a highly efficient Axiom™ 70 K SNP array for Pyrus and evaluation for high-density mapping and germplasm characterization. PMID:31046664
SeqTailor: a user-friendly webserver for the extraction of DNA or protein sequences from next-generation sequencing data. PMID:31045209
Further support linking the 22q11.2 microduplication to an increased risk of bladder exstrophy and highlighting LZTR1 as a candidate gene. PMID:31044557
Genetic diversity, population structure, and relationships in a collection of pepper (Capsicum spp.) landraces from the Spanish centre of diversity revealed by genotyping-by-sequencing (GBS). PMID:31044080
Goth migration induced changes in the matrilineal genetic structure of the central-east European population. PMID:31043639
A homeotic shift late in development drives mimetic color variation in a bumble bee. PMID:31043564
Chromosomal genome assembly of the ethanol production strain CBS 11270 indicates a highly dynamic genome structure in the yeast species Brettanomyces bruxellensis. PMID:31042716
Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding. PMID:31042285
A Chemical Genetic Method for Monitoring Genome-Wide Dynamics of O-GlcNAc Turnover on Chromatin-Associated Proteins. PMID:31041386
Loss-of-Function of a Tomato Receptor-Like Kinase Impairs Male Fertility and Induces Parthenocarpic Fruit Set. PMID:31040856
Differences in resource use lead to coexistence of seed-transmitted microbial populations. PMID:31040301
Characterization of the transcriptome of Haloferax volcanii, grown under four different conditions, with mixed RNA-Seq. PMID:31039177
Phenotypic sexual dimorphism is associated with genomic signatures of resolved sexual conflict. PMID:31038811
Altered Localization of Hybrid Incompatibility Proteins in Drosophila. PMID:31038678
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. PMID:31038454
A novel quantitative trait locus on chromosome A9 controlling oleic acid content in Brassica napus. PMID:31037811
Specific chromatin changes mark lateral organ founder cells in the Arabidopsis inflorescence meristem. PMID:31037302
The genetic history of admixture across inner Eurasia. PMID:31036896
Yeast expression of mammalian Onzin and fungal FCR1 suggests ancestral functions of PLAC8 proteins in mitochondrial metabolism and DNA repair. PMID:31036870
Ancient Mammalian and Plant DNA from Late Quaternary Stalagmite Layers at Solkota Cave, Georgia. PMID:31036834
TEFM regulates both transcription elongation and RNA processing in mitochondria. PMID:31036713
Defects in Efflux (oprM), β-Lactamase (ampC), and Lipopolysaccharide Transport (lptE) Genes Mediate Antibiotic Hypersusceptibility of Pseudomonas aeruginosa Strain Z61. PMID:31036686
Measuring sequencer size bias using REcount: a novel method for highly accurate Illumina sequencing-based quantification. PMID:31036053
Novel breeding approach for Japanese flounder using atmosphere and room temperature plasma mutagenesis tool. PMID:31035925
Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition. PMID:31035530
Nontuberculous Mycobacteria Persistence in a Cell Model Mimicking Alveolar Macrophages. PMID:31035520
Viral Chromosome Conformation Capture (V3C) Assays for Identifying Trans-interaction Sites between Lytic Viruses and the Cellular Genome. PMID:31032382
Targeted, High-Resolution RNA Sequencing of Non-coding Genomic Regions Associated With Neuropsychiatric Functions. PMID:31031799
An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation. PMID:31031115
Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities. PMID:31031003
Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression. PMID:31029541
DNAscan: personal computer compatible NGS analysis, annotation and visualisation. PMID:31029080
SciPipe: A workflow library for agile development of complex and dynamic bioinformatics pipelines. PMID:31029061
Cell-level somatic mutation detection from single-cell RNA sequencing. PMID:31028395
Whole exome sequencing reveals mutations in FAT1 tumor suppressor gene clinically impacting on peripheral T-cell lymphoma not otherwise specified. PMID:31028364
scMerge leverages factor analysis, stable expression, and pseudoreplication to merge multiple single-cell RNA-seq datasets. PMID:31028141
Instability of the Pseudoautosomal Boundary in House Mice. PMID:31028113
Agricultural Origins of a Highly Persistent Lineage of Vancomycin-Resistant Enterococcus faecalis in New Zealand. PMID:31028029
Genomic Diversity and Recombination among Xylella fastidiosa Subspecies. PMID:31028021
Adaptive Evolution within Gut Microbiomes of Healthy People. PMID:31028005
GPA: A Microbial Genetic Polymorphisms Assignments Tool in Metagenomic Analysis by Bayesian Estimation. PMID:31026578
Volatile 1-octen-3-ol increases patulin production by Penicillium expansum on a patulin-suppressing medium. PMID:31025195
Compromised global embryonic transcriptome associated with advanced maternal age. PMID:31025158
Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis. PMID:31024753
A High-Density Genetic Linkage Map and QTL Mapping for Sex in Black Tiger Shrimp (Penaeus monodon). PMID:31024632
Molecular Analysis of Evolution and Origins of Cultivated Hawthorn (Crataegus spp.) and Related Species in China. PMID:31024604
Taxonomic and Functional Characterization of the Microbial Community During Spontaneous in vitro Fermentation of Riesling Must. PMID:31024486
Family quarrels in seeds and rapid adaptive evolution in Arabidopsis. PMID:31023888
Breaking Free: The Genomics of Allopolyploidy-Facilitated Niche Expansion in White Clover. PMID:31023841
Complete Genome Sequence of Spiroplasma alleghenense PLHS-1T (ATCC 51752), a Bacterium Isolated from Scorpion Fly (Panorpa helena). PMID:31023800
Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells. PMID:31022887
Genome of 'Charleston Gray', the principal American watermelon cultivar, and genetic characterization of 1,365 accessions in the U.S. National Plant Germplasm System watermelon collection. PMID:31022325
Proteogenomic Annotation of Chinese Hamsters Reveals Extensive Novel Translation Events and Endogenous Retroviral Elements. PMID:31020842
Whole-Genome Annotation with BRAKER. PMID:31020555
Comparative Transcriptomic Profiling of Yersinia enterocolitica O:3 and O:8 Reveals Major Expression Differences of Fitness- and Virulence-Relevant Genes Indicating Ecological Separation. PMID:31020044
Chromosome-Level Assembly of the Chinese Seabass (Lateolabrax maculatus) Genome. PMID:31019525
Disruption in A-to-I Editing Levels Affects C. elegans Development More Than a Complete Lack of Editing. PMID:31018137
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. PMID:31018126
Genome streamlining via complete loss of introns has occurred multiple times in lichenized fungal mitochondria. PMID:31016002
Genomic, ecological, and morphological approaches to investigating species limits: A case study in modern taxonomy from Tropical Eastern Pacific surgeonfishes. PMID:31015983
Sequencing of human genomes with nanopore technology. PMID:31015479
Multiple myeloma immunoglobulin lambda translocations portend poor prognosis. PMID:31015454
Asgard archaea capable of anaerobic hydrocarbon cycling. PMID:31015394
Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis. PMID:31015328
Comprehensive characterization of T-DNA integration induced chromosomal rearrangement in a birch T-DNA mutant. PMID:31014254
Gene expression changes associated with the evolutionary loss of a metabolic trait: lack of lipogenesis in parasitoids. PMID:31014246
Identification of genomic regions associated with multi-silique trait in Brassica napus. PMID:31014236
Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities. PMID:31012313
Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling. PMID:31011859
Effects of long-term exercise on plasma adipokine levels and inflammation-related gene expression in subcutaneous adipose tissue in sedentary dysglycaemic, overweight men and sedentary normoglycaemic men of healthy weight. PMID:31011777
Assessment of Glyphosate Induced Epigenetic Transgenerational Inheritance of Pathologies and Sperm Epimutations: Generational Toxicology. PMID:31011160
Long-Term Conservation of Ohnologs Through Partial Tetrasomy Following Whole-Genome Duplication in Salmonidae. PMID:31010824
ChimeraMiner: An Improved Chimeric Read Detection Pipeline and Its Application in Single Cell Sequencing. PMID:31010074
The telomeric Cdc13-Stn1-Ten1 complex regulates RNA polymerase II transcription. PMID:31006804
Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs. PMID:31006620
BHap: a novel approach for bacterial haplotype reconstruction. PMID:31004480
DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage. PMID:31004132
CENTRORADIALIS Interacts with FLOWERING LOCUS T-Like Genes to Control Floret Development and Grain Number. PMID:31004004
Distribution and Phylogeny of Erythrocytic Necrosis Virus (ENV) in Salmon Suggests Marine Origin. PMID:31003511
Broad domains of histone 3 lysine 4 trimethylation are associated with transcriptional activation in CA1 neurons of the hippocampus during memory formation. PMID:31002880
Semen quality is affected by HLA class I alleles together with sexually transmitted diseases. PMID:31002754
Deep Genome Resequencing Reveals Artificial and Natural Selection for Visual Deterioration, Plateau Adaptability and High Prolificacy in Chinese Domestic Sheep. PMID:31001329
Laboratory Evolution of a Saccharomyces cerevisiae × S. eubayanus Hybrid Under Simulated Lager-Brewing Conditions. PMID:31001314
Overcoming Self-Incompatibility in Diploid Potato Using CRISPR-Cas9. PMID:31001300
Diurnal Temperature Variation and Plants Drive Latitudinal Patterns in Seasonal Dynamics of Soil Microbial Community. PMID:31001239
Alkylaminophenol Induces G1/S Phase Cell Cycle Arrest in Glioblastoma Cells Through p53 and Cyclin-Dependent Kinase Signaling Pathway. PMID:31001122
GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer. PMID:31000582
Whole Genome Sequencing and Re-sequencing of the Sable Antelope (Hippotragus niger): A Resource for Monitoring Diversity in ex Situ and in Situ Populations. PMID:31000506
GenHap: a novel computational method based on genetic algorithms for haplotype assembly. PMID:30999845
SQUAT: a Sequencing Quality Assessment Tool for data quality assessments of genome assemblies. PMID:30999844
From trash to treasure: detecting unexpected contamination in unmapped NGS data. PMID:30999839
A novel CRISPR/Cas9 associated technology for sequence-specific nucleic acid enrichment. PMID:30998719
R-ChIP for genome-wide mapping of R-loops by using catalytically inactive RNASEH1. PMID:30996261
The acute transcriptional response to resistance exercise: impact of age and contraction mode. PMID:30996129
Automated analysis of small RNA datasets with RAPID. PMID:30993044
Primed histone demethylation regulates shoot regenerative competency. PMID:30992430
Genome sequencing analysis of blood cells identifies germline haplotypes strongly associated with drug resistance in osteosarcoma patients. PMID:30991985
Genome-Wide SNP Discovery in Indigenous Cattle Breeds of South Africa. PMID:30988672
Evolution of buffering in a genetic circuit controlling plant stem cell proliferation. PMID:30988512
Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis. PMID:30988425
The horse Y chromosome as an informative marker for tracing sire lines. PMID:30988347
Adenine Methylation in Drosophila Is Associated with the Tissue-Specific Expression of Developmental and Regulatory Genes. PMID:30988038
Genetic Diversity of Salmonella Derby from the Poultry Sector in Europe. PMID:30987404
New Chondrosarcoma Cell Lines with Preserved Stem Cell Properties to Study the Genomic Drift During In Vitro/In Vivo Growth. PMID:30987403
Fluorescent Light Incites a Conserved Immune and Inflammatory Genetic Response within Vertebrate Organs (Danio Rerio, Oryzias Latipes and Mus Musculus). PMID:30987199
Transcriptomic Responses to Thermal Stress and Varied Phosphorus Conditions in Fugacium kawagutii. PMID:30987028
Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae. PMID:30986243
Genome-Wide Identification of Histone Modifications Involved in Placental Development in Pigs. PMID:30984246
Assessment of Autozygosity Derived From Runs of Homozygosity in Jinhua Pigs Disclosed by Sequencing Data. PMID:30984245
Quantitative Trait Loci for Freezing Tolerance in a Lowland x Upland Switchgrass Population. PMID:30984223
Genes Associated With Psychrotolerant Bacillus cereus Group Isolates. PMID:30984157
Expressional Profiling of Carpet Glia in the Developing Drosophila Eye Reveals Its Molecular Signature of Morphology Regulators. PMID:30983950
Integrated Transcriptomic and Proteomic Analysis of Primary Human Umbilical Vein Endothelial Cells. PMID:30983154
Inhibition of autotransporter biogenesis by small molecules. PMID:30983025
Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs. PMID:30982597
Analysis of the recombination landscape of hexaploid bread wheat reveals genes controlling recombination and gene conversion frequency. PMID:30982471
Variants in KIAA0825 underlie autosomal recessive postaxial polydactyly. PMID:30982135
Population Genetics of Paramecium Mitochondrial Genomes: Recombination, Mutation Spectrum, and Efficacy of Selection. PMID:30980669
Wetland Sediments Host Diverse Microbial Taxa Capable of Cycling Alcohols. PMID:30979841
Dietary walnut altered gene expressions related to tumor growth, survival, and metastasis in breast cancer patients: a pilot clinical trial. PMID:30979659
Beyond bulk: a review of single cell transcriptomics methodologies and applications. PMID:30978643
SNP and indel frequencies at transcription start sites and at canonical and alternative translation initiation sites in the human genome. PMID:30978217
Fine-mapping of angular leaf spot resistance gene Phg-2 in common bean and development of molecular breeding tools. PMID:30976830
Predictive models of eukaryotic transcriptional regulation reveals changes in transcription factor roles and promoter usage between metabolic conditions. PMID:30976803
Data on draft genome sequence of Bacillus sp. strain VKPM B-3276 isolated from Culex pipiens larvae. PMID:30976634
Pervasive admixture between eucalypt species has consequences for conservation and assisted migration. PMID:30976314
Patterns of genetic differentiation in Colorado potato beetle correlate with contemporary, not historic, potato land cover. PMID:30976311
Population genomic analyses reveal a highly differentiated and endangered genetic cluster of northern goshawks (Accipiter gentilis laingi) in Haida Gwaii. PMID:30976308
Genomic signatures of introgression between commercial and native bumblebees, Bombus terrestris, in western Iberian Peninsula-Implications for conservation and trade regulation. PMID:30976302
Y-chromosomal analysis of clan structure of Kalmyks, the only European Mongol people, and their relationship to Oirat-Mongols of Inner Asia. PMID:30976109
Large Enriched Fragment Targeted Sequencing (LEFT-SEQ) Applied to Capture of Wolbachia Genomes. PMID:30976027
"Candidatus Colwellia aromaticivorans" sp. nov., "Candidatus Halocyntiibacter alkanivorans" sp. nov., and "Candidatus Ulvibacter alkanivorans" sp. nov. Genome Sequences. PMID:30975799
Hypermorphic SERK1 Mutations Function via a SOBIR1 Pathway to Activate Floral Abscission Signaling. PMID:30975695
Zero-valent iron sand filtration reduces concentrations of virus-like particles and modifies virome community composition in reclaimed water used for agricultural irrigation. PMID:30975220
Whole genome sequencing reveals complexity in both HPV sequences present and HPV integrations in HPV-positive oropharyngeal squamous cell carcinomas. PMID:30975103
A splice donor variant in CCDC189 is associated with asthenospermia in Nordic Red dairy cattle. PMID:30975085
Genomic variants identified from whole-genome resequencing of indicine cattle breeds from Pakistan. PMID:30973947
Reconciling high-throughput gene essentiality data with metabolic network reconstructions. PMID:30973869
A high-density genetic map and molecular sex-typing assay for gerbils. PMID:30972478
A QTL for Number of Teats Shows Breed Specific Effects on Number of Vertebrae in Pigs: Bridging the Gap Between Molecular and Quantitative Genetics. PMID:30972109
Genome sequence analysis of the fairy ring-forming fungus Lepista sordida and gene candidates for interaction with plants. PMID:30971747
High quality reference genomes for toxigenic and non-toxigenic Vibrio cholerae serogroup O139. PMID:30971707
Impact of antibiotic treatment and host innate immune pressure on enterococcal adaptation in the human bloodstream. PMID:30971455
Comprehensive Identification of Fim-Mediated Inversions in Uropathogenic Escherichia coli with Structural Variation Detection Using Relative Entropy. PMID:30971446
Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies. PMID:30970016
Primary Coenzyme Q deficiency Due to Novel ADCK3 Variants, Studies in Fibroblasts and Review of Literature. PMID:30968303
Population Pharmacogenomics for Precision Public Health in Colombia. PMID:30967898
Systems Biology Reveals NR2F6 and TGFB1 as Key Regulators of Feed Efficiency in Beef Cattle. PMID:30967894
Novel potential causative genes in carotid paragangliomas. PMID:30967136
Exome-wide survey of the Siberian Caucasian population. PMID:30967127
GPU accelerated sequence alignment with traceback for GATK HaplotypeCaller. PMID:30967111
Long Non-Coding RNA Myoparr Regulates GDF5 Expression in Denervated Mouse Skeletal Muscle. PMID:30965639
Molecular evidence for recent divergence of X- and Y-linked gene pairs in Spinacia oleracea L. PMID:30964889
A western route of prehistoric human migration from Africa into the Iberian Peninsula. PMID:30963949
Spaceflight-induced alternative splicing during seedling development in Arabidopsis thaliana. PMID:30963109
Draft genome of the river water buffalo. PMID:30962899
In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens. PMID:30962622
Inheritance patterns of the transcriptome in hybrid chickens and their parents revealed by expression analysis. PMID:30962479
Compound heterozygous POMGNT1 mutations leading to muscular dystrophy-dystroglycanopathy type A3: a case report. PMID:30961548
gyrA and parC mutations in fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Kenya. PMID:30961546
The Primary Antisense Transcriptome of Halobacterium salinarum NRC-1. PMID:30959844
Small RNA responses of Culex mosquitoes and cell lines during acute and persistent virus infection. PMID:30959110
Recentrifuge: Robust comparative analysis and contamination removal for metagenomics. PMID:30958827
ATAC-seq Assay with Low Mitochondrial DNA Contamination from Primary Human CD4+ T Lymphocytes. PMID:30958473
Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA. PMID:30958261
Vertical differentiation in tropical forest butterflies: a novel mechanism generating insect diversity? PMID:30958212
Proteomic and transcriptomic experiments reveal an essential role of RNA degradosome complexes in shaping the transcriptome of Mycobacterium tuberculosis. PMID:30957850
Gross transcriptomic analysis of Pseudomonas putida for diagnosing environmental shifts. PMID:30957409
Gene Expression Pattern and Regulatory Network of α-Toxin Treatment in Bombyx mori. PMID:30956974
Specific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients. PMID:30956778
exceRpt: A Comprehensive Analytic Platform for Extracellular RNA Profiling. PMID:30956140
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. PMID:30955884
An unbiased in vitro screen for activating epidermal growth factor receptor mutations. PMID:30952700
Tissue-Specific Oncogenic Activity of KRASA146T. PMID:30952657
Design and characterization of an 87k SNP genotyping array for Arctic charr (Salvelinus alpinus). PMID:30951561
PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data. PMID:30951143
Genome sequencing for rightward hemispheric language dominance. PMID:30950222
Comparative population genomics identified genomic regions and candidate genes associated with fruit domestication traits in peach. PMID:30950186
Kluyveromyces marxianus developing ethanol tolerance during adaptive evolution with significant improvements of multiple pathways. PMID:30949239
Whole-Genome Resequencing Identifies KIT New Alleles That Affect Coat Color Phenotypes in Pigs. PMID:30949195
Wild Origins of Macadamia Domestication Identified Through Intraspecific Chloroplast Genome Sequencing. PMID:30949191
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis. PMID:30948729
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma. PMID:30948495
Genome-wide selection footprints and deleterious variations in young Asian allotetraploid rapeseed. PMID:30947395
In vivo recombination of Saccharomyces eubayanus maltose-transporter genes yields a chimeric transporter that enables maltotriose fermentation. PMID:30946741
A guinea fowl genome assembly provides new evidence on evolution following domestication and selection in galliformes. PMID:30945415
Precise therapeutic gene correction by a simple nuclease-induced double-stranded break. PMID:30944467
Phylogenetic Analysis of Mycobacterium tuberculosis Strains in Wales by Use of Core Genome Multilocus Sequence Typing To Analyze Whole-Genome Sequencing Data. PMID:30944195
Gene flow signature in the S-allele region of cultivated buckwheat. PMID:30943914
PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression. PMID:30943409
Identification of factors associated with duplicate rate in ChIP-seq data. PMID:30943272
Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World. PMID:30942856
Tumor mutation burden and recurrent tumors in hereditary lung cancer. PMID:30941903
Zinc Uptake and Storage During the Formation of the Cerebral Cortex in Mice. PMID:30941734
Whole genome sequencing analysis of horse populations inhabiting the Korean Peninsula and Przewalski's horse. PMID:30941726
Optimal translational fidelity is critical for Salmonella virulence and host interactions. PMID:30941426
Analysis of the Epigenome in Multiplex Pre-eclampsia Families Identifies SORD, DGKI, and ICA1 as Novel Candidate Risk Genes. PMID:30941163
Environmental interactions are regulated by temperature in Burkholderia seminalis TC3.4.2R3. PMID:30940839
A high-quality apple genome assembly reveals the association of a retrotransposon and red fruit colour. PMID:30940818
Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly. PMID:30940689
OMICfpp: a fuzzy approach for paired RNA-Seq counts. PMID:30940089
QTL fine-mapping of soybean (Glycine max L.) leaf type associated traits in two RILs populations. PMID:30940069
Population genomics identifies patterns of genetic diversity and selection in chicken. PMID:30940068
Stochastic processes drive rapid genomic divergence during experimental range expansions. PMID:30940062
Genome Sequencing of Polydrug-, Multidrug-, and Extensively Drug-Resistant Mycobacterium tuberculosis Strains from South India. PMID:30938706
Transcriptome Sequence of Antibiotic-Treated Pseudomonas aeruginosa. PMID:30938705
Sequencing a Juglans regia × J. microcarpa hybrid yields high-quality genome assemblies of parental species. PMID:30937174
Localized production of defence chemicals by intracellular symbionts of Haliclona sponges. PMID:30936484
beditor: A Computational Workflow for Designing Libraries of Guide RNAs for CRISPR-Mediated Base Editing. PMID:30936113
Pathway-based polygene risk for severe depression implicates drug metabolism in CONVERGE. PMID:30935430
Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy. PMID:30934880
Evolutionary expression differences of creatine synthesis-related genes: Implications for skeletal muscle metabolism in fish. PMID:30931999
Genomic, Transcriptomic, and Epigenomic Features Differentiate Genes That Are Relevant for Muscular Polyunsaturated Fatty Acids in the Common Carp. PMID:30930941
Programmable Base Editing of the Sheep Genome Revealed No Genome-Wide Off-Target Mutations. PMID:30930940
A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis. PMID:30929900
The anti-cancer drugs curaxins target spatial genome organization. PMID:30926878
The identification of differentially expressed genes between extremes of placental efficiency in maternal line gilts on day 95 of gestation. PMID:30925895
The genome of the giant Nomura's jellyfish sheds light on the early evolution of active predation. PMID:30925871
DNA methylation and functional characterization of the XIST gene during in vitro early embryo development in cattle. PMID:30925851
The Impact of Natural Selection on Short Insertion and Deletion Variation in the Great Tit Genome. PMID:30924871
Metabolic comparison of aerial and submerged mycelia formed in the liquid surface culture of Cordyceps militaris. PMID:30924317
Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow. PMID:30924299
Next-generation sequencing of HIV-1 single genome amplicons. PMID:30923677
Relative abundance and molecular evolution of Lake Sinai Virus (Sinaivirus) clades. PMID:30923646
Selene: a PyTorch-based deep learning library for sequence data. PMID:30923381
Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor. PMID:30923315
The Whole Genome Sequence and mRNA Transcriptome of the Tropical Cyclopoid Copepod Apocyclops royi. PMID:30923136
CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses. PMID:30923043
Progressive Pseudorheumatoid Dysplasia resolved by whole exome sequencing: a novel mutation in WISP3 and review of the literature. PMID:30922245
Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance. PMID:30922221
Copy number variation study in Japanese quail associated with stress related traits using whole genome re-sequencing data. PMID:30921419
The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing. PMID:30921322
rPinecone: Define sub-lineages of a clonal expansion via a phylogenetic tree. PMID:30920366
Lower Respiratory Tract Microbiome and Resistome of Bovine Respiratory Disease Mortalities. PMID:30918994
Setting boundaries for genome-wide heterochromatic DNA deletions through flanking inverted repeats in Tetrahymena thermophila. PMID:30918956
Genome-wide profiling of RNA editing sites in sheep. PMID:30918658
Genome-wide identification and characterization of long noncoding and circular RNAs in germline stem cells. PMID:30918261
Diagnosis of fusion genes using targeted RNA sequencing. PMID:30918253
A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy. PMID:30918111
Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans. PMID:30918042
Predicting enhancers in mammalian genomes using supervised hidden Markov models. PMID:30917778
Placenta Transcriptome Profiling in Intrauterine Growth Restriction (IUGR). PMID:30917529
Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse Model. PMID:30917328
Construction of a high-density interspecific (Lens culinaris x L. odemensis) genetic map based on functional markers for mapping morphological and agronomical traits, and QTLs affecting resistance to Ascochyta in lentil. PMID:30917174
Osmotic stress activates nif and fix genes and induces the Rhizobium tropici CIAT 899 Nod factor production via NodD2 by up-regulation of the nodA2 operon and the nodA3 gene. PMID:30917160
The molecular mechanism of dsRNA processing by a bacterial Dicer. PMID:30916338
Detection of Differentially Expressed Cleavage Site Intervals Within 3' Untranslated Regions Using CSI-UTR Reveals Regulated Interaction Motifs. PMID:30915105
Compound Heterozygous CHAT Gene Mutations of a Large Deletion and a Missense Variant in a Chinese Patient With Severe Congenital Myasthenic Syndrome With Episodic Apnea. PMID:30914958
Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma. PMID:30914738
Genomic Variants Among Threatened Acropora Corals. PMID:30914426
Evaluating next-generation sequencing (NGS) methods for routine monitoring of wild bees: Metabarcoding, mitogenomics or NGS barcoding. PMID:30912868
Evidence for Faster X Chromosome Evolution in Spiders. PMID:30912801
Introgression of the chromosomal region with the Pi-cd locus from Oryza meridionalis into O. sativa L. during rice domestication. PMID:30911779
RNA-sequencing in ophthalmology research: considerations for experimental design and analysis. PMID:30911735
Efficient Genomic Interval Queries Using Augmented Range Trees. PMID:30911095
Molecular evidence supports a genic capture resolution of the lek paradox. PMID:30911052
CREDO: Highly confident disease-relevant A-to-I RNA-editing discovery in breast cancer. PMID:30911020
Mapping Gene Markers for Apple Fruit Ring Rot Disease Resistance Using a Multi-omics Approach. PMID:30910819
let-7 coordinates the transition to adulthood through a single primary and four secondary targets. PMID:30910805
Brown rat demography reveals pre-commensal structure in eastern Asia before expansion into Southeast Asia. PMID:30910795
UTAP: User-friendly Transcriptome Analysis Pipeline. PMID:30909881
Sequencing and Phylogenetic Analysis of Chloroplast Genes in Freshwater Raphidophytes. PMID:30909525
A Deep-sequencing-assisted, Spontaneous Suppressor Screen in the Fission Yeast Schizosaccharomyces pombe. PMID:30907886
Codweb: Whole-genome sequencing uncovers extensive reticulations fueling adaptation among Atlantic, Arctic, and Pacific gadids. PMID:30906856
Genome-wide identification and expression analysis of the AAAP family in Medicago truncatula. PMID:30905050
Comparative Genomics Reveals the Genetic Mechanisms of Musk Secretion and Adaptive Immunity in Chinese Forest Musk Deer. PMID:30903183
ORE identifies extreme expression effects enriched for rare variants. PMID:30903145
Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism. PMID:30902980
Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway. PMID:30902546
Sunbeam: an extensible pipeline for analyzing metagenomic sequencing experiments. PMID:30902113
Pathogenic Gene Mutations or Variants Identified by Targeted Gene Sequencing in Adults With Hemophagocytic Lymphohistiocytosis. PMID:30899265
Comparative Genome and Transcriptome Study of the Gene Expression Difference Between Pathogenic and Environmental Strains of Prototheca zopfii. PMID:30899253
The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor. PMID:30899015
An Ultra-Dense Haploid Genetic Map for Evaluating the Highly Fragmented Genome Assembly of Norway Spruce (Picea abies). PMID:30898899
Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors. PMID:30898839
Genomic epidemiology of erythromycin-resistant Bordetella pertussis in China. PMID:30898080
Helicase/SUMO-targeted ubiquitin ligase Uls1 interacts with the Holliday junction resolvase Yen1. PMID:30897139
Hypomorphic mutation of the mouse Huntington's disease gene orthologue. PMID:30897080
Evolution and Diversification of Kiwifruit Mitogenomes through Extensive Whole-Genome Rearrangement and Mosaic Loss of Intergenic Sequences in a Highly Variable Region. PMID:30895302
Endometrial receptivity enhancement through induced injury and repair during ovarian stimulation: the Receptivity Enhancement by Follicular-phase Renewal after Endometrial ScratcHing (REFRESH) trial protocol. PMID:30895236
Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European National Reference Center: Neisseria meningitidis as a Proof-of-Concept. PMID:30894839
Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers. PMID:30894686
Differential gene expression in response to eCry3.1Ab ingestion in an unselected and eCry3.1Ab-selected western corn rootworm (Diabrotica virgifera virgifera LeConte) population. PMID:30894586
Insight into the genome and brackish water adaptation strategies of toxic and bloom-forming Baltic Sea Dolichospermum sp. UHCC 0315. PMID:30894564
Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer. PMID:30894541
Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes. PMID:30894540
Genome of Crucihimalaya himalaica, a close relative of Arabidopsis, shows ecological adaptation to high altitude. PMID:30894495
Antarctic Penguins as Reservoirs of Diversity for Avian Avulaviruses. PMID:30894472
Rapid cell division of Staphylococcus aureus during colonization of the human nose. PMID:30894139
Treg-Cell Control of a CXCL5-IL-17 Inflammatory Axis Promotes Hair-Follicle-Stem-Cell Differentiation During Skin-Barrier Repair. PMID:30893588
Mitogenomes illuminate the origin and migration patterns of the indigenous people of the Canary Islands. PMID:30893316
Drosophila p53 directs nonapoptotic programs in postmitotic tissue. PMID:30892991
Phenotypic and genetic diversity in aposematic Malagasy poison frogs (genus Mantella). PMID:30891212
Contrasting patterns of divergence at the regulatory and sequence level in European Daphnia galeata natural populations. PMID:30891195
Ultra-Sensitive CSF3R Deep Sequencing in Patients With Severe Congenital Neutropenia. PMID:30891028
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. PMID:30890717
Positive selection in Europeans and East-Asians at the ABCA12 gene. PMID:30890716
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans. PMID:30890702
A novel transcriptome-derived SNPs array for tench (Tinca tinca L.). PMID:30889192
An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease. PMID:30889179
Guy1, a Y-linked embryonic signal, regulates dosage compensation in Anopheles stephensi by increasing X gene expression. PMID:30888319
Gossypium barbadense and Gossypium hirsutum genomes provide insights into the origin and evolution of allotetraploid cotton. PMID:30886425
Low genetic variation is associated with low mutation rate in the giant duckweed. PMID:30886148
Genomic and Functional Analysis of Emerging Virulent and Multidrug-Resistant Escherichia coli Lineage Sequence Type 648. PMID:30885899
The Transcriptional Landscape of Marek's Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes. PMID:30884829
Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles. PMID:30882366
A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin. PMID:30881690
A Novel Heterozygous Mutation of the COL4A3 Gene Causes a Peculiar Phenotype without Hematuria and Renal Function Impairment in a Chinese Family. PMID:30881523
A k-mer grammar analysis to uncover maize regulatory architecture. PMID:30876396
Cellular Gene Expression during Hepatitis C Virus Replication as Revealed by Ribosome Profiling. PMID:30875926
DNA Methylation Patterns in the Round Goby Hypothalamus Support an On-The-Spot Decision Scenario for Territorial Behavior. PMID:30875862
Loss of function mutations in essential genes cause embryonic lethality in pigs. PMID:30875370
Systematic analysis of Type I-E Escherichia coli CRISPR-Cas PAM sequences ability to promote interference and primed adaptation. PMID:30875129
A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression. PMID:30874608
Respiratory viruses identified in western Canadian beef cattle by metagenomic sequencing and their association with bovine respiratory disease. PMID:30873724
Sequencing the Plastid Genome of Giant Ragweed (Ambrosia trifida, Asteraceae) From a Herbarium Specimen. PMID:30873197
Genomic analysis of the emergence of drug-resistant strains of Mycobacterium tuberculosis in the Middle East. PMID:30872748
'Genome skimming' with the MinION hand-held sequencer identifies CITES-listed shark species in India's exports market. PMID:30872700
Genome-wide Analysis of bZIP Transcription Factors in wheat and Functional Characterization of a TabZIP under Abiotic Stress. PMID:30872683
Analyses of 202 plastid genomes elucidate the phylogeny of Solanum section Petota. PMID:30872631
Functional divergence of thyrotropin beta-subunit paralogs gives new insights into salmon smoltification metamorphosis. PMID:30872608
A reference-grade wild soybean genome. PMID:30872580
Transcriptome profiling of Plasmodium vivax in Saimiri monkeys identifies potential ligands for invasion. PMID:30872477
A virome-wide clonal integration analysis platform for discovering cancer viral etiology. PMID:30872350
Performance evaluation of commercial library construction kits for PCR-based targeted sequencing using a unique molecular identifier. PMID:30871467
Similarities and differences between variants called with human reference genome HG19 or HG38. PMID:30871461
Genome-Wide Assessment of Avocado Germplasm Determined from Specific Length Amplified Fragment Sequencing and Transcriptomes: Population Structure, Genetic Diversity, Identification, and Application of Race-Specific Markers. PMID:30871275
Possible cross-feeding pathway of facultative methylotroph Methyloceanibacter caenitepidi Gela4 on methanotroph Methylocaldum marinum S8. PMID:30870453
Molecular characterization of Bathymodiolus mussels and gill symbionts associated with chemosynthetic habitats from the U.S. Atlantic margin. PMID:30870419
Identification of Hfq-binding RNAs in Caulobacter crescentus. PMID:30870072
Functional characterization of HSFs from wheat in response to heat and other abiotic stress conditions. PMID:30868385
Genome-wide profiling of Epstein-Barr virus integration by targeted sequencing in Epstein-Barr virus associated malignancies. PMID:30867819
Metatranscriptomic exploration of microbial functioning in clouds. PMID:30867542
Loss of the Polycomb group protein Rnf2 results in derepression of tbx-transcription factors and defects in embryonic and cardiac development. PMID:30867528
Featherweight long read alignment using partitioned reference indexes. PMID:30867495
Whole-genome resequencing of 472 Vitis accessions for grapevine diversity and demographic history analyses. PMID:30867414
Comparative Transcriptomic Analysis Provides Insight into the Domestication and Improvement of Pear (P. pyrifolia) Fruit. PMID:30867332
Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements. PMID:30867223
A multi-parent recombinant inbred line population of C. elegans allows identification of novel QTLs for complex life history traits. PMID:30866929
YPR2 is a regulator of light modulated carbon and secondary metabolism in Trichoderma reesei. PMID:30866811
Machine learning applied to transcriptomic data to identify genes associated with feed efficiency in pigs. PMID:30866799
Interspecific delimitation and relationships among four Ostrya species based on plastomes. PMID:30866795
Genetic diversity and host adaptation of avian H5N1 influenza viruses during human infection. PMID:30866780
Liquid Biopsies in Lung Cancer: Four Emerging Technologies and Potential Clinical Applications. PMID:30866571
Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing. PMID:30865901
Sex-Biased Gene Expression and Dosage Compensation on the Artemia franciscana Z-Chromosome. PMID:30865260
MitoZ: a toolkit for animal mitochondrial genome assembly, annotation and visualization. PMID:30864657
Early-onset triple-negative breast cancer in multiracial/ethnic populations: Distinct trends of prevalence of truncation mutations. PMID:30864286
Studies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway. PMID:30863400
Nasal Resistome Development in Infants With Cystic Fibrosis in the First Year of Life. PMID:30863369
Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila. PMID:30862957
Ectopic expression of Snord115 in choroid plexus interferes with editing but not splicing of 5-Ht2c receptor pre-mRNA in mice. PMID:30862860
Maternal Gastrointestinal Nematode Infection Up-regulates Expression of Genes Associated with Long-Term Potentiation in Perinatal Brains of Uninfected Developing Pups. PMID:30862816
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly. PMID:30862798
Mitotic Recombination and Rapid Genome Evolution in the Invasive Forest Pathogen Phytophthora ramorum. PMID:30862749
Highly Resolved Systems Biology to Dissect the Etioplast-to-Chloroplast Transition in Tobacco Leaves. PMID:30862726
Ancient Mitochondrial Genomes Reveal the Absence of Maternal Kinship in the Burials of Çatalhöyük People and Their Genetic Affinities. PMID:30862131
Parallel Speciation of Wild Rice Associated with Habitat Shifts. PMID:30861529
Differential Gene Expression Supports a Resource-Intensive, Defensive Role for Colony Production in the Bloom-Forming Haptophyte, Phaeocystis globosa. PMID:30860641
Relative Mutation Rates in Nucleomorph-Bearing Algae. PMID:30859201
Ploidy Determination in the Pathogenic Fungus Sporothrix spp. PMID:30858833
Rapid Sequencing of Multiple RNA Viruses in Their Native Form. PMID:30858830
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice. PMID:30858552
PKD1 Duplicated regions limit clinical Utility of Whole Exome Sequencing for Genetic Diagnosis of Autosomal Dominant Polycystic Kidney Disease. PMID:30858458
Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging. PMID:30858410
A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma. PMID:30858363
Genetics of Variable Disease Expression Conferred by Inverse Gene-For-Gene Interactions in the Wheat-Parastagonospora nodorum Pathosystem. PMID:30858234
A Prediction Model for Preoperative Risk Assessment in Endometrial Cancer Utilizing Clinical and Molecular Variables. PMID:30857319
Population Substructure Has Implications in Validating Next-Generation Cancer Genomics Studies with TCGA. PMID:30857229
Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment. PMID:30854478
Novel Compound Heterozygous Mutations in the TRAPPC9 Gene in Two Siblings With Autism and Intellectual Disability. PMID:30853973
Global Responses of Resistant and Susceptible Sorghum (Sorghum bicolor) to Sugarcane Aphid (Melanaphis sacchari). PMID:30853964
Prdm9 and Meiotic Cohesin Proteins Cooperatively Promote DNA Double-Strand Break Formation in Mammalian Spermatocytes. PMID:30853435
Genome sequence of Xanthomonas fuscans subsp. fuscans strain Xff49: a new isolate obtained from common beans in Southern Brazil. PMID:30850979
CBP and SRF co-regulate dendritic growth and synaptic maturation. PMID:30850733
Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage. PMID:30850636
Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype. PMID:30850595
Pleiotropic Effects of c-di-GMP Content in Pseudomonas syringae. PMID:30850427
Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake. PMID:30850347
Genetic Variation in Pan Species Is Shaped by Demographic History and Harbors Lineage-Specific Functions. PMID:30847478
Asymmetric introgression between fishes in the Red River basin of Texas is associated with variation in water quality. PMID:30847094
Recurrent hotspot SF3B1 mutations at codon 625 in vulvovaginal mucosal melanoma identified in a study of 27 Australian mucosal melanomas. PMID:30847022
Differential gene expression induced by Verteporfin in endometrial cancer cells. PMID:30846786
Cell cycle- and genomic distance-dependent dynamics of a discrete chromosomal region. PMID:30846483
Tracking dengue virus type 1 genetic diversity during lineage replacement in an hyperendemic area in Colombia. PMID:30845200
Development and Application of InDel Markers for Capsicum spp. Based on Whole-Genome Re-Sequencing. PMID:30842649
The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection. PMID:30842630
Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease. PMID:30842500
Genomic and metagenomic signatures of giant viruses are ubiquitous in water samples from sewage, inland lake, waste water treatment plant, and municipal water supply in Mumbai, India. PMID:30842490
Age-related gene and miRNA expression changes in airways of healthy individuals. PMID:30842487
Separation of breast cancer and organ microenvironment transcriptomes in metastases. PMID:30841919
Behavioral heterogeneity in quorum sensing can stabilize social cooperation in microbial populations. PMID:30841874
Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control. PMID:30840897
Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair. PMID:30840882
Sequence specific suppression of androgen receptor-DNA binding in vivo by a Py-Im polyamide. PMID:30838415
Kir2.2 p.Thr140Met: a genetic susceptibility to sporadic periodic paralysis. PMID:30838349
Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)-First Report of Clinical and Imaging Features from India, and a Novel SACS Gene Duplication. PMID:30838287
First Report of Kufor-Rakeb Syndrome (PARK 9) from India, and a Novel Nonsense Mutation in ATP13A2 Gene. PMID:30838237
Efficient Bioelectrochemical Conversion of Industrial Wastewater by Specific Strain Isolation and Community Adaptation. PMID:30838205
Making Sense of the Epigenome Using Data Integration Approaches. PMID:30837884
Phenotypic and transcriptomic characterization of canine myeloid-derived suppressor cells. PMID:30837603
CRISPR/CAS9 targeted CAPTURE of mammalian genomic regions for characterization by NGS. PMID:30837529
'Meiotic genes' are constitutively expressed in an asexual amoeba and are not necessarily involved in sexual reproduction. PMID:30836881
Epigenetic and transcriptional profiling of triple negative breast cancer. PMID:30835260
Transcriptome Sequencing and Analysis of Changes Associated with Insecticide Resistance in the Dengue Mosquito (Aedes aegypti) in Vietnam. PMID:30834881
Genome Resequencing of Laboratory Stocks of Burkholderia pseudomallei K96243. PMID:30834386
Identification of the Germline Mutation Profile in Esophageal Squamous Cell Carcinoma by Whole Exome Sequencing. PMID:30833958
hCLE/RTRAF-HSPC117-DDX1-FAM98B: A New Cap-Binding Complex That Activates mRNA Translation. PMID:30833903
Identification and genetic characterization of a novel Orthobunyavirus species by a straightforward high-throughput sequencing-based approach. PMID:30833612
Microbial abundance, activity and population genomic profiling with mOTUs2. PMID:30833550
Redefining the Small Regulatory RNA Transcriptome in Streptococcus pneumoniae Serotype 2 Strain D39. PMID:30833353
Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite Plasmodium falciparum. PMID:30833341
The neoepitope landscape of breast cancer: implications for immunotherapy. PMID:30832597
An insight into the sialotranscriptome and virome of Amazonian anophelines. PMID:30832587
Patterns of genomic differentiation between two Lake Victoria cichlid species, Haplochromis pyrrhocephalus and H. sp. 'macula'. PMID:30832572
Population Genomics and Structure of the Critically Endangered Mariana Crow (Corvus kubaryi). PMID:30832245
Transcriptome Analysis Reveals Key Cold-Stress-Responsive Genes in Winter Rapeseed (Brassica rapa L.). PMID:30832221
Insights into the Genomics of Clownfish Adaptive Radiation: Genetic Basis of the Mutualism with Sea Anemones. PMID:30830203
Time to Treatment Prediction in Chronic Lymphocytic Leukemia Based on New Transcriptional Patterns. PMID:30828568
A comprehensive assessment of inbreeding and laboratory adaptation in Aedes aegypti mosquitoes. PMID:30828375
Xist Deletional Analysis Reveals an Interdependency between Xist RNA and Polycomb Complexes for Spreading along the Inactive X. PMID:30827740
Expanding the Boundaries of RNA Sequencing as a Diagnostic Tool for Rare Mendelian Disease. PMID:30827497
Genetic mapping of powdery mildew resistance genes in soybean by high-throughput genome-wide sequencing. PMID:30826863
Expression Divergence as an Evolutionary Alternative Mechanism Adopted by Two Rice Subspecies Against Rice Blast Infection. PMID:30825020
Nanopore sequencing of long ribosomal DNA amplicons enables portable and simple biodiversity assessments with high phylogenetic resolution across broad taxonomic scale. PMID:30824940
High density linkage map construction and QTL mapping for runner production in allo-octoploid strawberry Fragaria × ananassa based on ddRAD-seq derived SNPs. PMID:30824841

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nucleic acid sequence
metasource: Fairsharing.org
version: FAIRsharing.org: SAM; Sequence Alignment Map; DOI: https://doi.org/10.25504/FAIRsharing.k97xzh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:12 p.m.

sequence alignment
metasource: Fairsharing.org
version: FAIRsharing.org: SAM; Sequence Alignment Map; DOI: https://doi.org/10.25504/FAIRsharing.k97xzh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:12 p.m.

region
metasource: Fairsharing.org
version: FAIRsharing.org: SAM; Sequence Alignment Map; DOI: https://doi.org/10.25504/FAIRsharing.k97xzh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:12 p.m.

nucleic acid sequence sequence alignment region

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Binary Alignment Map Format

CLUSTAL-W Alignment Format

Multiple Alignment Format

Chain Format for pairwise alignment

Axt Alignment Format

Stockholm Multiple Alignment Format

net alignment annotation Format

Multiple Alignment using Fast Fourier Transform

INSD sequence record XML

NCBI Trace Archives

HMMER Profile File Format

Gene Transfer Format

BLAST-like Alignment Tool Format

Genome Variation Format

BAliBASE

DDBJ Trace Archive

Sequence Read Archive

Pre-Clustering File Format

GenBank Sequence Format

Big Multiple Alignment Format