Development and application of a next-generation sequencing protocol and bioinformatics pipeline for the comprehensive analysis of the canine immunoglobulin repertoire.
PMID:35802654
Immunoglobulin Heavy Chain High-Throughput Sequencing in Pediatric B-Precursor Acute Lymphoblastic Leukemia: Is the Clonality of the Disease at Diagnosis Related to Its Prognosis?
PMID:35712632
A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice.
PMID:35679349
Vaccines and Immunoinformatics for Vaccine Design.
PMID:35594022
Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination.
PMID:35478188
Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22.
PMID:35464476
Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque.
PMID:35419009
Variations in antibody repertoires correlate with vaccine responses.
PMID:35361626
IMGT®Homo sapiens IG and TR Loci, Gene Order, CNV and Haplotypes: New Concepts as a Paradigm for Jawed Vertebrates Genome Assemblies.
PMID:35327572
Bacillus Calmette-Guérin Treatment Changes the Tumor Microenvironment of Non-Muscle-Invasive Bladder Cancer.
PMID:35311085
No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults.
PMID:35224466
Stage-Specific Non-Coding RNA Expression Patterns during In Vitro Human B Cell Differentiation into Antibody Secreting Plasma Cells.
PMID:35202088
Structural Basis for Unusual TCR CDR3β Usage Against an Immunodominant HIV-1 Gag Protein Peptide Restricted to an HLA-B*81:01 Molecule.
PMID:35173732
Follicular T cells optimize the germinal center response to SARS-CoV-2 protein vaccination in mice.
PMID:35139367
The contribution of uncharted RNA sequences to tumor identity in lung adenocarcinoma.
PMID:35118386
Structural Basis of Antibody Conformation and Stability Modulation by Framework Somatic Hypermutation.
PMID:35046963
Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome.
PMID:35022065
Pembrolizumab and decitabine for refractory or relapsed acute myeloid leukemia.
PMID:35017151
Development of a fully canine anti-canine CTLA4 monoclonal antibody for comparative translational research in dogs with spontaneous tumors.
PMID:34856888
The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
PMID:34852239
Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients.
PMID:34785098
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
PMID:34534459
Nanopore sequencing approach for immunoglobulin gene analysis in chronic lymphocytic leukemia.
PMID:34480068
Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics.
PMID:34447370
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers.
PMID:34437125
Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein.
PMID:34384783
Mechanisms of Immunotoxicity: Stressors and Evaluators.
PMID:34361007
The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self.
PMID:34292314
Acetate differentially regulates IgA reactivity to commensal bacteria.
PMID:34262176
Neutralizing Antibody Induction Associated with a Germline Immunoglobulin Gene Polymorphism in Neutralization-Resistant SIVsmE543-3 Infection.
PMID:34205728
A diverse collection of B cells responded to HIV infection in infant BG505.
PMID:34195680
Potent RBD-specific neutralizing rabbit monoclonal antibodies recognize emerging SARS-CoV-2 variants elicited by DNA prime-protein boost vaccination.
PMID:34120577
Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations.
PMID:34120151
Dynamic regulation of B cell complement signaling is integral to germinal center responses.
PMID:34031614
Human transitional and IgMlow mature naïve B cells preserve permissive B-cell receptors.
PMID:33988890
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
PMID:33948592
Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
PMID:33794145
CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells.
PMID:33761980
A single donor is sufficient to produce a highly functional in vitro antibody library.
PMID:33742103
In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19.
PMID:33716737
HLA class I-associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children.
PMID:33705359
Immunoregulatory and lipid presentation pathways are upregulated in human face transplant rejection.
PMID:33667197
TCR β chain-directed bispecific antibodies for the treatment of T cell cancers.
PMID:33649188
Evolution of thymopoietic microenvironments.
PMID:33622100
Immunoinformatics Approach for the Identification and Characterization of T Cell and B Cell Epitopes towards the Peptide-Based Vaccine against SARS-CoV-2.
PMID:33546870
A Potent anti-Simian Immunodeficiency Virus Neutralizing Antibody Induction Associated with a Germline Immunoglobulin Gene Polymorphism in Rhesus Macaques.
PMID:33441342
IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics.
PMID:33211804
Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome.
PMID:33200133
Gut-educated IgA plasma cells defend the meningeal venous sinuses.
PMID:33149302
Tunable dynamics of B cell selection in gut germinal centres.
PMID:33116306
Passive Immunization Delays Disease Outcome in Gilthead Sea Bream Infected With Enteromyxum leei (Myxozoa), Despite the Moderate Changes in IgM and IgT Repertoire.
PMID:33013935
Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses.
PMID:33010224
Immunoglobulins or Antibodies: IMGT® Bridging Genes, Structures and Functions.
PMID:32878258
Study of B Cell Repertoire in Patients With Anti-N-Methyl-D-Aspartate Receptor Encephalitis.
PMID:32849520
Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR.
PMID:32744131
Deciphering and predicting CD4+ T cell immunodominance of influenza virus hemagglutinin.
PMID:32644114
IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms.
PMID:32636395
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.
PMID:32540903
T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
PMID:32532817
Computational Model Reveals a Stochastic Mechanism behind Germinal Center Clonal Bursts.
PMID:32532145
BCR selection and affinity maturation in Peyer's patch germinal centres.
PMID:32499646
Massively parallel interrogation and mining of natively paired human TCRαβ repertoires.
PMID:32393905
Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design.
PMID:32379792
Automated analysis of immunosequencing datasets reveals novel immunoglobulin D genes across diverse species.
PMID:32339161
Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein.
PMID:32269069
Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures.
PMID:32264741
GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells.
PMID:32248243
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans.
PMID:32106283
Simultaneous Immunoglobulin A and G Glycopeptide Profiling for High-Throughput Applications.
PMID:32091889
Diversity and Function of Maternal HIV-1-Specific Antibodies at the Time of Vertical Transmission.
PMID:32075936
Molecular profiling of immunoglobulin heavy-chain gene rearrangements unveils new potential prognostic markers for multiple myeloma patients.
PMID:32029700
Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messenger RNA sequencing.
PMID:31964864
Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting.
PMID:31866068
Transitions of CDR-L3 Loop Canonical Cluster Conformations on the Micro-to-Millisecond Timescale.
PMID:31803187
IGHV mutational status of nodal marginal zone lymphoma by NGS reveals distinct pathogenic pathways with different prognostic implications.
PMID:31802229
Radiotherapy Eradicates Malignant T Cells and Is Associated with Improved Survival in Early-Stage Mycosis Fungoides.
PMID:31636100
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
PMID:31628339
VDJbase: an adaptive immune receptor genotype and haplotype database.
PMID:31602484
Unclassifiable Isolated Monoclonal Lymphocytosis: Comprehensive Description of a Retrospective Cohort.
PMID:31590326
Stabilization of soluble high-affinity T-cell receptor with de novo disulfide bonds.
PMID:31552676
David vs. Goliath: The Structure, Function, and Clinical Prospects of Antibody Fragments.
PMID:31544834
Peptides for Infectious Diseases: From Probe Design to Diagnostic Microarrays.
PMID:31544829
Preferential Identification of Agonistic OX40 Antibodies by Using Cell Lysate to Pan Natively Paired, Humanized Mouse-Derived Yeast Surface Display Libraries.
PMID:31544823
A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients.
PMID:31501610
Class-Switch Recombination Occurs Infrequently in Germinal Centers.
PMID:31375460
Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data.
PMID:31329576
Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan.
PMID:31315032
Alternative conformations of a major antigenic site on RSV F.
PMID:31306469
Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors.
PMID:31226930
Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
PMID:31126879
Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design.
PMID:31042706
Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.
PMID:31023536
Oligoclonal immunoglobulin repertoire in biliary remnants of biliary atresia.
PMID:30872727
miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.
PMID:30856173
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping.
PMID:30733445
A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus.
PMID:30590046
Deamidation and isomerization liability analysis of 131 clinical-stage antibodies.
PMID:30526254
An HIV-1 Broadly Neutralizing Antibody from a Clade C-Infected Pediatric Elite Neutralizer Potently Neutralizes the Contemporaneous and Autologous Evolving Viruses.
PMID:30429339
Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies.
PMID:30271892
Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method.
PMID:30252602
Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity.
PMID:30170813
Combined Influence of B-Cell Receptor Rearrangement and Somatic Hypermutation on B-Cell Class-Switch Fate in Health and in Chronic Lymphocytic Leukemia.
PMID:30147686
Exploring the pre-immune landscape of antigen-specific T cells.
PMID:30144804
Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites.
PMID:30135211
TCRmodel: high resolution modeling of T cell receptors from sequence.
PMID:29790966
B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
PMID:29765016
Unbiased quantification of immunoglobulin diversity at the DNA level with VDJ-seq.
PMID:29725123
AbDb: antibody structure database-a database of PDB-derived antibody structures.
PMID:29718130
RosettaAntibodyDesign (RAbD): A general framework for computational antibody design.
PMID:29702641
IRProfiler - a software toolbox for high throughput immune receptor profiling.
PMID:29669518
The Immune Landscape of Cancer.
PMID:29628290
Optimisation of ex vivo memory B cell expansion/differentiation for interrogation of rare peripheral memory B cell subset responses.
PMID:29588920
B-cell tumor development in Tet2-deficient mice.
PMID:29581109
Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding.
PMID:29568296
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.
PMID:29554084
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
PMID:29554083
c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont.
PMID:29414937
A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library.
PMID:29376776
On being the right size: antibody repertoire formation in the mouse and human.
PMID:29260260
Informatics for cancer immunotherapy.
PMID:29253114
Antibody-Based Protective Immunity against Helminth Infections: Antibody Phage Display Derived Antibodies against BmR1 Antigen.
PMID:29165352
In Silico Prediction Analysis of Idiotope-Driven T-B Cell Collaboration in Multiple Sclerosis.
PMID:29038659
Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing αβ T cell clones.
PMID:28945199
Comprehensive annotation and evolutionary insights into the canine (Canis lupus familiaris) antigen receptor loci.
PMID:28924718
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
PMID:28847005
Rare, high-affinity mouse anti-PD-1 antibodies that function in checkpoint blockade, discovered using microfluidics and molecular genomics.
PMID:28846506
Rare, high-affinity anti-pathogen antibodies from human repertoires, discovered using microfluidics and molecular genomics.
PMID:28846502
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.
PMID:28825697
The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability.
PMID:28795125
Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia.
PMID:28751718
Exposure to the Epstein-Barr Viral Antigen Latent Membrane Protein 1 Induces Myelin-Reactive Antibodies In Vivo.
PMID:28729867
Low-dose radiation accelerates aging of the T-cell receptor repertoire in CBA/Ca mice.
PMID:28667356
De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.
PMID:28648661
Quantifiable predictive features define epitope-specific T cell receptor repertoires.
PMID:28636592
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
PMID:28566371
Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age.
PMID:28546550
Research Techniques Made Simple: High-Throughput Sequencing of the T-Cell Receptor.
PMID:28532760
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
PMID:28467828
Clinicopathological features and outcome of chronic lymphocytic leukaemia in Chinese patients.
PMID:28424415
Dysregulated signaling, proliferation and apoptosis impact on the pathogenesis of TCRγδ+ T cell large granular lymphocyte leukemia.
PMID:28407008
Surveillance states.
PMID:28384134
Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
PMID:28358435
Structural reconstruction of protein ancestry.
PMID:28356519
Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens.
PMID:28329770
CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.
PMID:28300170
BRILIA: Integrated Tool for High-Throughput Annotation and Lineage Tree Assembly of B-Cell Repertoires.
PMID:28144239
Antigen Processing in the Endoplasmic Reticulum Is Monitored by Semi-Invariant αβ TCRs Specific for a Conserved Peptide-Qa-1b MHC Class Ib Ligand.
PMID:28108559
VH1 Family Immunoglobulin Repertoire Sequencing after Allogeneic Hematopoietic Stem Cell Transplantation.
PMID:28095438
High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities.
PMID:28077404
Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.
PMID:28076415
Shared HLA Class I and II Alleles and Clonally Restricted Public and Private Brain-Infiltrating αβ T Cells in a Cohort of Rasmussen Encephalitis Surgery Patients.
PMID:28066418
Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
PMID:28025250
Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.
PMID:28011932
RAG Recombinase as a Selective Pressure for Genome Evolution.
PMID:27979968
An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.
PMID:27841852
An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes.
PMID:27815444
Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.
PMID:27783711
Applicability of predictive toxicology methods for monoclonal antibody therapeutics: status Quo and scope.
PMID:27766364
Dynamic variation of CD5 surface expression levels within individual chronic lymphocytic leukemia clones.
PMID:27693386
Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq.
PMID:27668657
Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001.
PMID:27630232
Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin.
PMID:27604323
Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors.
PMID:27588903
Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
PMID:27560183
Genomic and expression analyses of Tursiops truncatus T cell receptor gamma (TRG) and alpha/delta (TRA/TRD) loci reveal a similar basic public γδ repertoire in dolphin and human.
PMID:27528257
A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.
PMID:27438765
Single-cell analysis of glandular T cell receptors in Sjögren's syndrome.
PMID:27358913
HIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant.
PMID:27345369
Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia.
PMID:27295298
Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations.
PMID:27224912
Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VL libraries from immunized animals.
PMID:27224530
Epstein-Barr virus nuclear protein EBNA3C directly induces expression of AID and somatic mutations in B cells.
PMID:27217538
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia.
PMID:27191993
NKG2D-NKG2D Ligand Interaction Inhibits the Outgrowth of Naturally Arising Low-Grade B Cell Lymphoma In Vivo.
PMID:27183590
Maximum-Entropy Models of Sequenced Immune Repertoires Predict Antigen-Antibody Affinity.
PMID:27074145
B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice.
PMID:27048211
Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting.
PMID:26998518
T cell fate and clonality inference from single-cell transcriptomes.
PMID:26950746
Isolation of Anti-Ricin Protective Antibodies Exhibiting High Affinity from Immunized Non-Human Primates.
PMID:26950154
Immunoglobulin gene rearrangements in Chinese and Italian patients with chronic lymphocytic leukemia.
PMID:26943037
Visualizing antibody affinity maturation in germinal centers.
PMID:26912368
Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis.
PMID:26858965
The Diversity and Molecular Evolution of B-Cell Receptors during Infection.
PMID:26802217
Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8(+) T cell receptor alpha repertoire following allogeneic transplantation.
PMID:26800118
Consistency of VDJ Rearrangement and Substitution Parameters Enables Accurate B Cell Receptor Sequence Annotation.
PMID:26751373
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
PMID:26700814
A method to confer Protein L binding ability to any antibody fragment.
PMID:26683650
Immune history profoundly affects broadly protective B cell responses to influenza.
PMID:26631631
Immunoinformatics and epitope prediction in the age of genomic medicine.
PMID:26589500
Estimate of within population incremental selection through branch imbalance in lineage trees.
PMID:26586802
The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo.
PMID:26523376
Crossreactive αβ T Cell Receptors Are the Predominant Targets of Thymocyte Negative Selection.
PMID:26522985
TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL.
PMID:26446955
Stability engineering of anti-EGFR scFv antibodies by rational design of a lambda-to-kappa swap of the VL framework using a structure-guided approach.
PMID:26337947
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.
PMID:26307665
Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma.
PMID:26228486
Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability.
PMID:26220042
Quantifying evolutionary constraints on B-cell affinity maturation.
PMID:26194758
Dynamics of immunoglobulin sequence diversity in HIV-1 infected individuals.
PMID:26194755
The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains.
PMID:26194750
Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease.
PMID:26160175
Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota.
PMID:26147688
State of the Human Proteome in 2014/2015 As Viewed through PeptideAtlas: Enhancing Accuracy and Coverage through the AtlasProphet.
PMID:26139527
HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.
PMID:26089355
Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis.
PMID:26077231
IgRepertoireConstructor: a novel algorithm for antibody repertoire construction and immunoproteogenomics analysis.
PMID:26072509
Longitudinal analysis of peripheral blood T cell receptor diversity in patients with systemic lupus erythematosus by next-generation sequencing.
PMID:26001779
Immunoglobulin VH gene diversity and somatic hypermutation during SIV infection of rhesus macaques.
PMID:25994147
Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects.
PMID:25985925
Improved genome inference in the MHC using a population reference graph.
PMID:25915597
Production of α2,6-sialylated IgG1 in CHO cells.
PMID:25875452
Reconstructing and mining the B cell repertoire with ImmunediveRsity.
PMID:25875140
Hypergravity exposure during gestation modifies the TCRβ repertoire of newborn mice.
PMID:25792033
Adaptive mutations alter antibody structure and dynamics during affinity maturation.
PMID:25756188
V genes in primates from whole genome sequencing data.
PMID:25721877
Recognition determinants of broadly neutralizing human antibodies against dengue viruses.
PMID:25581790
Peptide/MHC tetramer-based sorting of CD8⁺ T cells to a leukemia antigen yields clonotypes drawn nonspecifically from an underlying restricted repertoire.
PMID:25576336
Antibody-specific model of amino acid substitution for immunological inferences from alignments of antibody sequences.
PMID:25534034
Genomic analysis offers insights into the evolution of the bovine TRA/TRD locus.
PMID:25408163
PyIgClassify: a database of antibody CDR structural classifications.
PMID:25392411
Frequency Patterns of T-Cell Exposed Amino Acid Motifs in Immunoglobulin Heavy Chain Peptides Presented by MHCs.
PMID:25389426
Old questions, new tools: does next-generation sequencing hold the key to unraveling intestinal B-cell responses?
PMID:25389035
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia.
PMID:25388851
IMGT®, the international ImMunoGeneTics information system® 25 years on.
PMID:25378316
Discovery of invariant T cells by next-generation sequencing of the human TCR α-chain repertoire.
PMID:25339678
Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice.
PMID:25318652
Examining variable domain orientations in antigen receptors gives insight into TCR-like antibody design.
PMID:25233457
Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods.
PMID:25189176
AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.
PMID:25179679
The MEC1 and MEC2 lines represent two CLL subclones in different stages of progression towards prolymphocytic leukemia.
PMID:25162594
Elevated T cell receptor signaling identifies a thymic precursor to the TCRαβ(+)CD4(-)CD8β(-) intraepithelial lymphocyte lineage.
PMID:25131532
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.
PMID:25123191
Diversity in the preimmune immunoglobulin repertoire of SHR lines susceptible and resistant to end-organ injury.
PMID:25056448
Quantification of IgM molecular response by droplet digital PCR as a potential tool for the early diagnosis of sepsis.
PMID:25043844
Tissue-specific expressed antibody variable gene repertoires.
PMID:24956460
Improving the accuracy of the structure prediction of the third hypervariable loop of the heavy chains of antibodies.
PMID:24930144
Innate PLZF+CD4+ αβ T cells develop and expand in the absence of Itk.
PMID:24928994
Diversity of the murine antibody response targeting influenza A(H1N1pdm09) hemagglutinin.
PMID:24928044
Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cells.
PMID:24927543
Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies Against HIV-1.
PMID:24917864
Prognostic B-cell signatures using mRNA-seq in patients with subtype-specific breast and ovarian cancer.
PMID:24916698
Neuroblastoma killing properties of Vδ2 and Vδ2-negative γδT cells following expansion by artificial antigen-presenting cells.
PMID:24893631
Genomic V exons from whole genome shotgun data in reptiles.
PMID:24893587
Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection.
PMID:24821801
Cynomolgus and pigtail macaque IgG subclasses: characterization of IGHG genes and computational analysis of IgG/Fc receptor binding affinity.
PMID:24811270
Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing.
PMID:24809667
Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation.
PMID:24795717
Peptides from the variable region of specific antibodies are shared among lung cancer patients.
PMID:24787687
Clinical diagnosis and typing of systemic amyloidosis in subcutaneous fat aspirates by mass spectrometry-based proteomics.
PMID:24747948
Assessment of fully automated antibody homology modeling protocols in molecular operating environment.
PMID:24715627
Immunoglobulin and T Cell Receptor Genes: IMGT(®) and the Birth and Rise of Immunoinformatics.
PMID:24600447
Chimeric plantibody passively protects mice against aerosolized ricin challenge.
PMID:24574537
Genome-wide structural modelling of TCR-pMHC interactions.
PMID:24564684
Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors.
PMID:24555054
Multivariate Analysis Using High Definition Flow Cytometry Reveals Distinct T Cell Repertoires between the Fetal-Maternal Interface and the Peripheral Blood.
PMID:24550917
Multigene families of immunoglobulin domain-containing innate immune receptors in zebrafish: deciphering the differences.
PMID:24548770
Trials and Tribulations with VH Replacement.
PMID:24523721
Persistence and selection of an expanded B-cell clone in the setting of rituximab therapy for Sjögren's syndrome.
PMID:24517398
Genomic characteristics of the T cell receptor (TRB) locus in the rabbit (Oryctolagus cuniculus) revealed by comparative and phylogenetic analyses.
PMID:24500788
Polyreactive monoclonal autoantibodies in multiple sclerosis: functional selection from phage display library and characterization by deep sequencing analysis.
PMID:24455188
Dynamics of inter-heavy chain interactions in human immunoglobulin G (IgG) subclasses studied by kinetic Fab arm exchange.
PMID:24425871
Decreased mutation frequencies among immunoglobulin G variable region genes during viremic HIV-1 infection.
PMID:24409278
The past, present, and future of immune repertoire biology - the rise of next-generation repertoire analysis.
PMID:24348479
CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.
PMID:24312094
The human IgE repertoire.
PMID:24296690
SAbDab: the structural antibody database.
PMID:24214988
Impact of new sequencing technologies on studies of the human B cell repertoire.
PMID:24161653
Deep sequencing and Circos analyses of antibody libraries reveal antigen-driven selection of Ig VH genes during HIV-1 infection.
PMID:24158018
Structural basis for the antibody neutralization of herpes simplex virus.
PMID:24100313
Characterizing immunoglobulin repertoire from whole blood by a personal genome sequencer.
PMID:24058670
Cross-neutralization of four paramyxoviruses by a human monoclonal antibody.
PMID:23955151
Temporal dynamics of clonal evolution in chronic lymphocytic leukemia with stereotyped IGHV4-34/IGKV2-30 antigen receptors: longitudinal immunogenetic evidence.
PMID:23922244
Unifying model for molecular determinants of the preselection Vβ repertoire.
PMID:23918392
A novel rabbit monoclonal antibody platform to dissect the diverse repertoire of antibody epitopes for HIV-1 Env immunogen design.
PMID:23864612
Prediction of site-specific interactions in antibody-antigen complexes: the proABC method and server.
PMID:23803466
High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells.
PMID:23802841
Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations.
PMID:23742949
MAPs: a database of modular antibody parts for predicting tertiary structures and designing affinity matured antibodies.
PMID:23718826
A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells.
PMID:23708250
Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
PMID:23696737
The Missing Heritability in T1D and Potential New Targets for Prevention.
PMID:23691517
The important role of T cells and receptor expression in Sjögren's syndrome.
PMID:23679844
MH2c: Characterization of major histocompatibility α-helices - an information criterion approach.
PMID:23564964
Cloning of a hamster anti-mouse CD79B antibody sequences and identification of a new hamster immunoglobulin lambda constant IGLC gene region.
PMID:23558558
Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
PMID:23524883
Conformational epitope consisting of the V3 and V4 loops as a target for potent and broad neutralization of simian immunodeficiency viruses.
PMID:23468483
Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study.
PMID:23458999
IMGT/Collier-de-Perles: a two-dimensional visualization tool for amino acid domain sequences.
PMID:23432825
Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses.
PMID:23236279
Onset of immune senescence defined by unbiased pyrosequencing of human immunoglobulin mRNA repertoires.
PMID:23226220
In silico design, construction and cloning of Trastuzumab humanized monoclonal antibody: A possible biosimilar for Herceptin.
PMID:23210080
Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.
PMID:23184990
Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3.
PMID:23049948
Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface.
PMID:22996451
Chromatin conformation governs T-cell receptor Jβ gene segment usage.
PMID:22984176
Application of circular consensus sequencing and network analysis to characterize the bovine IgG repertoire.
PMID:22978666
Why must T cells be cross-reactive?
PMID:22918468
Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features.
PMID:22915760
Bispecific engineered antibody domains (nanoantibodies) that interact noncompetitively with an HIV-1 neutralizing epitope and FcRn.
PMID:22879932
Structural and comparative analysis of the T cell receptor gamma (TRG) locus in Oryctolagus cuniculus.
PMID:22772779
Immunoglobulin analysis tool: a novel tool for the analysis of human and mouse heavy and light chain transcripts.
PMID:22754554
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.
PMID:22745174
In vivo VL-targeted microbial superantigen induced global shifts in the B cell repertoire.
PMID:22696444
IMGT-ONTOLOGY 2012.
PMID:22654892
Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes.
PMID:22590602
Development of a humanized antibody with high therapeutic potential against dengue virus type 2.
PMID:22563515
Model IgG monoclonal autoantibody-anti-idiotype pair for dissecting the humoral immune response to oxidized low density lipoprotein.
PMID:22509912
T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection.
PMID:22491952
Distinct innate immunity pathways to activation and tolerance in subgroups of chronic lymphocytic leukemia with distinct immunoglobulin receptors.
PMID:22437326
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies.
PMID:22415752
The energetic basis underpinning T-cell receptor recognition of a super-bulged peptide bound to a major histocompatibility complex class I molecule.
PMID:22343629
Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4⁺ T-cell repertoire selection.
PMID:22314361
Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing.
PMID:22287713
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine.
PMID:22249449
Expressed antibody repertoires in human cord blood cells: 454 sequencing and IMGT/HighV-QUEST analysis of germline gene usage, junctional diversity, and somatic mutations.
PMID:22200891
Organization, complexity and allelic diversity of the porcine (Sus scrofa domestica) immunoglobulin lambda locus.
PMID:22186825
High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells.
PMID:22160929
Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells.
PMID:22160618
Evolution of the porcine (Sus scrofa domestica) immunoglobulin kappa locus through germline gene conversion.
PMID:22109540
The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse.
PMID:22075990
Cytomegalovirus-specific CD8+ T cells targeting different peptide/HLA combinations demonstrate varying T-cell receptor diversity.
PMID:22044339
Rep-Seq: uncovering the immunological repertoire through next-generation sequencing.
PMID:22043864
Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape.
PMID:22043016
Partial versus productive immunoglobulin heavy locus rearrangements in chronic lymphocytic leukemia: implications for B-cell receptor stereotypy.
PMID:21968789
Evolutionarily conserved features contribute to αβ T cell receptor specificity.
PMID:21962492
Torque teno virus 10 isolated by genome amplification techniques from a patient with concomitant chronic lymphocytic leukemia and polycythemia vera.
PMID:21953418
High-resolution description of antibody heavy-chain repertoires in humans.
PMID:21829618
Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells.
PMID:21789596
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
PMID:21788410
Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients.
PMID:21750087
Characterization and allelic polymorphisms of rhesus macaque (Macaca mulatta) IgG Fc receptor genes.
PMID:21327607
Specific binding of the pathogenic prion isoform: development and characterization of a humanized single-chain variable antibody fragment.
PMID:21283753
Insights into the innate immunity of the Mediterranean mussel Mytilus galloprovincialis.
PMID:21269501
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection.
PMID:21220454
Paired analysis of TCRα and TCRβ chains at the single-cell level in mice.
PMID:21135507
A new clustering of antibody CDR loop conformations.
PMID:21035459
Restricted V gene usage and VH/VL pairing of mouse humoral response against the N-terminal immunodominant epitope of the amyloid β peptide.
PMID:20970857
Clustering-based identification of clonally-related immunoglobulin gene sequence sets.
PMID:20875155
Regulation of the B cell receptor repertoire and self-reactivity by BAFF.
PMID:20817867
Immunoinformatics: an integrated scenario.
PMID:20722763
Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia.
PMID:20644084
Immune responses are characterized by specific shared immunoglobulin peptides that can be detected by proteomic techniques.
PMID:20615873
Copy number variation and association over T-cell receptor genes--influence of DNA source.
PMID:20582410
Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
PMID:20538861
Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements.
PMID:20495067
From IMGT-ONTOLOGY to IMGT/LIGMotif: the IMGT standardized approach for immunoglobulin and T cell receptor gene identification and description in large genomic sequences.
PMID:20433708
Personal genomes in progress: from the human genome project to the personal genome project.
PMID:20373666
Initial genomics of the human nucleolus.
PMID:20361057
Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice.
PMID:20220085
A novel paradigm for cell and molecule interaction ontology: from the CMM model to IMGT-ONTOLOGY.
PMID:20167082
Annotation and classification of the bovine T cell receptor delta genes.
PMID:20144200
Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin.
PMID:20110421
Analysis of cross-reactive and specific anti-carbohydrate antibodies against lipopolysaccharide from Chlamydophila psittaci.
PMID:20022906
IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T cell receptors, MHC, IgSF and MhcSF.
PMID:19900967
Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire.
PMID:19875695
AntigenDB: an immunoinformatics database of pathogen antigens.
PMID:19820110
Toward effective HIV vaccination: induction of binary epitope reactive antibodies with broad HIV neutralizing activity.
PMID:19726674
Narcolepsy is strongly associated with the T-cell receptor alpha locus.
PMID:19412176
Immunoinformatics: current trends and future directions.
PMID:19379830