Human Ageing Genomic Resources
Names
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Human Ageing Genomic Resources
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
HAGR
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
HAGR - Human Ageing Genomic Resources
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
Human Ageing Genomic Resources
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
HAGR
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
HAGR - Human Ageing Genomic Resources
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Other names: HAGR, HAGR - Human Ageing Genomic Resources
Names
More detailed information about this field from each metasource.
Human Ageing Genomic Resources
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
HAGR
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
HAGR - Human Ageing Genomic Resources
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools for the biology and genetics of ageing. HAGR features several databases with high-quality, manually-curated data: 1) GenAge, a database of genes associated with ageing in humans and model organisms; 2) AnAge, an extensive collection of longevity records and complementary traits for over 4,000 vertebrate species; and 3) GenDR, a database containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction.
Description
More detailed information about this field from each metasource.
The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools for the biology and genetics of ageing. HAGR features several databases with high-quality, manually-curated data: 1) GenAge, a database of genes associated with ageing in humans and model organisms; 2) AnAge, an extensive collection of longevity records and complementary traits for over 4,000 vertebrate species; and 3) GenDR, a database containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction.
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
The Human Ageing Genomic Resources (HAGR, http://genomics.senescence.info) is a freely available, online collection of research databases and tools for the biology and genetics of ageing. HAGR features now several databases with high-quality, manually-curated data: 1) GenAge, a database of genes associated with ageing in humans and model organisms; 2) AnAge, an extensive collection of longevity records and complementary traits for over 4,000 vertebrate species; and 3) GenDR, a newly incorporated database, containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction. Since its creation (1), major efforts have been undertaken to maintain the quality of data in HAGR, while further continuing to develop, improve and extend it. Altogether, we hope that through its improvements the current version of HAGR will continue to provide users with the most-comprehensive and accessible resources available today in the field of biogerontology.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools designed to help researchers study the genetics of human ageing using modern approaches such as functional genomics, network analyses, systems biology and evolutionary analyses.
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
Webpage:
http://genomics.senescence.info/Webpage
More detailed information about this field from each metasource.
http://genomics.senescence.info/
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
https://genomics.senescence.info/
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
Licence:
Name: HAGR Disclaimer, Credits and CopyrightLicence name
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HAGR Disclaimer, Credits and Copyright
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Public Domain
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
Licence URL
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http://genomics.senescence.info/legal.html
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
https://genomics.senescence.info/legal.html
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
Publications:
Publications
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The Human Ageing Genomic Resources: online databases and tools for biogerontologists
PMID: 18986374
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gks1155
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
The Human Ageing Genomic Resources: online databases and tools for biogerontologists
PMID: 18986374
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gks1155
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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The Human Ageing Genomic Resources: online databases and tools for biogerontologists
PubMed citations: 76.
76 articles citing: The Human Ageing Genomic Resources: online databases and tools for biogerontologists
Automated recognition and analysis of head thrashes behavior in C. elegans. PMID:35255825
Machine learning-based predictions of dietary restriction associations across ageing-related genes. PMID:34983372
A single-cell transcriptomic atlas of primate pancreatic islet aging. PMID:34691567
Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci. PMID:34227937
Computational tools for geroscience. PMID:33241167
Sex differences in age-to-maturation relate to sexual selection and adult sex ratios in birds. PMID:32055410
Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals. PMID:31730540
Telomere shortening rate predicts species life span. PMID:31285335
Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species. PMID:30978202
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence. PMID:30026603
Genomic Approach to Understand the Association of DNA Repair with Longevity and Healthy Aging Using Genomic Databases of Oldest-Old Population. PMID:29854078
ClueNet: Clustering a temporal network based on topological similarity rather than denseness. PMID:29738568
Human Ageing Genomic Resources: new and updated databases. PMID:29121237
Hypoxia tolerance, longevity and cancer-resistance in the mole rat Spalax - a liver transcriptomics approach. PMID:29084988
A review of supervised machine learning applied to ageing research. PMID:28265788
Exploratory bioinformatics investigation reveals importance of "junk" DNA in early embryo development. PMID:28231763
The post-genomic era of biological network alignment. PMID:28194172
Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan. PMID:27163160
The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan. PMID:26638078
Preadult life history variation determines adult transcriptome expression. PMID:26615085
Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma. PMID:26103567
Exploring the structure and function of temporal networks with dynamic graphlets. PMID:26072480
Mining the modular structure of protein interaction networks. PMID:25856434
Wing bone laminarity is not an adaptation for torsional resistance in bats. PMID:25780775
Deciphering life history transcriptomes in different environments. PMID:25442828
Exome sequencing of three cases of familial exceptional longevity. PMID:25116423
Genome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs. PMID:25096499
Comparative genetics of longevity and cancer: insights from long-lived rodents. PMID:24981598
Evolution of human longevity uncoupled from caloric restriction mechanisms. PMID:24400080
Mitochondrial inverted repeats strongly correlate with lifespan: mtDNA inversions and aging. PMID:24069185
Evolutionary Modeling of Genotype-Phenotype Associations, and Application to Primate Coding and Non-coding mtDNA Rate Variation. PMID:23926418
A decline in PABPN1 induces progressive muscle weakness in oculopharyngeal muscle dystrophy and in muscle aging. PMID:23793615
Systems biology in aging: linking the old and the young. PMID:23633915
Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges. PMID:23423909
Chapter 9: Analyses using disease ontologies. PMID:23300417
Discovery of molecular associations among aging, stem cells, and cancer based on gene expression profiling. PMID:23298462
Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing. PMID:23193293
Prediction of C. elegans longevity genes by human and worm longevity networks. PMID:23144747
Co-regulation of polar mRNA transport and lifespan in budding yeast Saccharomyces cerevisiae. PMID:23111244
Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases. PMID:23090008
GeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases. PMID:23039964
Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes. PMID:22912585
Concerted perturbation observed in a hub network in Alzheimer's disease. PMID:22815752
DEFOG: discrete enrichment of functionally organized genes. PMID:22706384
A method to find longevity-selected positions in the mammalian proteome. PMID:22701678
Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS). PMID:22445811
Codon usage bias as a function of generation time and life expectancy. PMID:22368389
A network-based approach on elucidating the multi-faceted nature of chronological aging in S. cerevisiae. PMID:22216232
Accelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevity. PMID:22205409
Molecular links between cellular senescence, longevity and age-related diseases - a systems biology perspective. PMID:22184282
Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes. PMID:22174010
Classifying DNA repair genes by kernel-based support vector machines. PMID:22125395
Aging-kb: a knowledge base for the study of the aging process. PMID:22100666
Genome-environment interactions that modulate aging: powerful targets for drug discovery. PMID:22090473
RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice. PMID:22073188
Gadd45 proteins: relevance to aging, longevity and age-related pathologies. PMID:21986581
FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1. PMID:21893079
Dominating biological networks. PMID:21887225
A genome-wide association study of aging. PMID:21782286
GiSAO.db: a database for ageing research. PMID:21609420
Postmyocardial infarct remodeling and heart failure: potential contributions from pro- and antiaging factors. PMID:21559227
Enabling enrichment analysis with the Human Disease Ontology. PMID:21550421
A role for Ras signaling in modulating mammalian aging by the GH/IGF1 axis. PMID:21512206
A genetic analysis of nitric oxide-mediated signaling during chronological aging in the yeast. PMID:21424154
An ontology-neutral framework for enrichment analysis. PMID:21347088
A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-related. PMID:21226956
Gerontome: a web-based database server for aging-related genes and analysis pipelines. PMID:21143804
Computational biology for ageing. PMID:21115530
Identification of evolutionarily conserved genetic regulators of cellular aging. PMID:20883526
Metabolic networks of longevity. PMID:20603007
Inferring the functions of longevity genes with modular subnetwork biomarkers of Caenorhabditis elegans aging. PMID:20128910
miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging. PMID:20089119
Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions. PMID:19900591
Network strategies to understand the aging process and help age-related drug design. PMID:19804610
Disease-aging network reveals significant roles of aging genes in connecting genetic diseases. PMID:19779549
The effect of osteoprotegerin gene modification on wear debris-induced osteolysis in a murine model of knee prosthesis failure. PMID:19665222 - http://dx.doi.org/10.1093/nar/gks1155
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aging
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
disease
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
model organism
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
phenotype
metasource: Fairsharing.org
version: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
human genes and diseases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
general human genetics databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
cancer
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
genetics
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
genomics
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
gerontology
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
human aging
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
protein-protein interactions
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
systems biology
metasource: re3data.org
version: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
Tags
More detailed information about this field from each metasource.
aging
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
disease
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
model organism
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
phenotype
metasource: Fairsharing.orgversion: FAIRsharing.org: HAGR; Human Ageing Genomic Resources; DOI: https://doi.org/10.25504/FAIRsharing.bw1e90; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
human genes and diseases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
general human genetics databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
cancer
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
genetics
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
genomics
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
gerontology
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
human aging
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
protein-protein interactions
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
systems biology
metasource: re3data.orgversion: re3data.org: HAGR; editing status 2021-11-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R34W81 last accessed: 2022-11-04
aging disease model organism phenotype human genes and diseases general human genetics cancer genetics genomics gerontology human aging protein-protein interactions systems biology
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