R3D643 last accessed: 2022-11-04

genecards
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

Other names: GeneCards, The Human Gene Database, genecards

This source may no longer be available. No known URL could be resolved successfully.

GeneCards is a searchable, integrated, database of human genes that provides concise genomic, transcriptomic, genetic, proteomic, functional and disease related information on all known and predicted human genes.

Webpage:

http://www.genecards.org/

Licence:

Name: GeneCards Privacy Policy
URL: http://www.lifemapsc.com/genecards-suite-privacy-policy/

Publications: (9)

Publications
More detailed information about this field from each metasource.

GeneCards Version 3: the human gene integrator
PMID: 20689021
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

GeneCards: integrating information about genes, proteins and diseases
PMID: 9097728
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support
PMID: 9789091
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

GeneCards 2002: towards a complete, object-oriented, human gene compendium
PMID: 12424129
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

http://dx.doi.org/10.1186/s12864-016-2722-2
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

http://dx.doi.org/10.1093/database/baw030
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

http://dx.doi.org/10.1002/cpbi.5
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

http://dx.doi.org/10.1089/omi.2015.0168
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

http://dx.doi.org/10.1093/database/bav006
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

GeneCards Version 3: the human gene integrator PubMed citations: 515.

515 articles citing: GeneCards Version 3: the human gene integrator

Multi-Level Biological Network Analysis and Drug Repurposing Based on Leukocyte Transcriptomics in Severe COVID-19: In Silico Systems Biology to Precision Medicine. PMID:35887528
Network Pharmacology-Based Strategy to Investigate the Mechanisms of Cibotium barometz in Treating Osteoarthritis. PMID:35873632
Mechanism of Action of Yin Nourishing and Heat Clearing Prescription in Treating Cough Variant Asthma Based on Network Pharmacology and Molecular Docking Verification. PMID:35866040
Toxoplasma infection in male mice alters dopamine-sensitive behaviors and host gene expression patterns associated with neuropsychiatric disease. PMID:35857765
Network Pharmacological Study on the Mechanism of Cynanchum paniculatum (Xuchangqing) in the Treatment of Bungarus multicinctus Bites. PMID:35837378
A Novel Ferroptosis-Related Gene Signature to Predict Prognosis of Esophageal Carcinoma. PMID:35813863
Network pharmacology and bioinformatics analysis identified essential genes of Jingulian in the treatment of rheumatoid arthritis and COVID-19. PMID:35813340
Identification of molecular mechanisms underlying the therapeutic effects of Xintong granule in coronary artery disease by a network pharmacology and molecular docking approach. PMID:35801781
Multiple Mechanisms of Shenqi Pill in Treating Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Molecular Docking. PMID:35795275
Network Pharmacology-Based Strategy to Investigate the Pharmacologic Mechanisms of Coptidis Rhizoma for the Treatment of Alzheimer's Disease. PMID:35795239
[Exploration of the therapeutic mechanism of Yiqi Jiedu recipe for treatment of primary liver cancer based on network pharmacology and molecular docking]. PMID:35790430
Pharmacological analysis of Empagliflozin: Acting through the CaMKII pathway in type 2 diabetes and acute cardiovascular events. PMID:35767566
Qishen Yiqi Dripping Pill Protects Diabetic Nephropathy by Inhibiting the PI3K-AKT Signaling Pathways in Rats. PMID:35754685
Network Pharmacology and Bioinformatics Approach Reveals the Multi-Target Pharmacological Mechanism of Fumaria indica in the Treatment of Liver Cancer. PMID:35745580
State of the Science for Kidney Disorders in Phelan-McDermid Syndrome: UPK3A, FBLN1, WNT7B, and CELSR1 as Candidate Genes. PMID:35741804
Identification of key apoptosis-related genes and immune infiltration in the pathogenesis of psoriasis. PMID:35729678
Integrating Network Pharmacology and Experimental Validation to Explore the Key Mechanism of Gubitong Recipe in the Treatment of Osteoarthritis. PMID:35720033
The tumor mutational landscape of BRCA2-deficient primary and metastatic prostate cancer. PMID:35715489
[Huangqi Sijunzi decoction for treating cancer-related fatigue in breast cancer patients: a randomized trial and network pharmacology study]. PMID:35673907
The Neuroprotective Effect of Shenmai Injection on Oxidative Stress Injury in PC12 Cells Based on Network Pharmacology. PMID:35668778
Precision environmental health monitoring by longitudinal exposome and multi-omics profiling. PMID:35667843
Study on Mechanism of Invigorating Qi and Promoting Blood Circulation in Treatment of Angiogenesis after Myocardial Infarction Using Network Pharmacology. PMID:35656461
Network Pharmacology Approach for Medicinal Plants: Review and Assessment. PMID:35631398
Immune-Related Protein Interaction Network in Severe COVID-19 Patients toward the Identification of Key Proteins and Drug Repurposing. PMID:35625619
Identification of Differential Genes of DNA Methylation Associated With Alzheimer's Disease Based on Integrated Bioinformatics and Its Diagnostic Significance. PMID:35615586
Yaobishu Regulates Inflammatory, Metabolic, Autophagic, and Apoptosis Pathways to Attenuate Lumbar Disc Herniation. PMID:35615578
In Silico Screening of Synthetic and Natural Compounds to Inhibit the Binding Capacity of Heavy Metal Compounds against EGFR Protein of Lung Cancer. PMID:35607306
Exploration of the System-Level Mechanisms of the Herbal Drug FDY003 for Pancreatic Cancer Treatment: A Network Pharmacological Investigation. PMID:35591866
The potential effects and mechanisms of hispidulin in the treatment of diabetic retinopathy based on network pharmacology. PMID:35590353
Exploring Molecular Mechanisms of Aloe barbadmsis Miller on Diphenoxylate-Induced Constipation in Mice. PMID:35571728
A Prognostic Model of Differentiated Thyroid Cancer Based on Up-Regulated Glycolysis-Related Genes. PMID:35528004
Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis. PMID:35523810
The clinical value of miRNA-21 in cervical cancer: A comprehensive investigation based on microarray datasets. PMID:35486636
Mechanism of Jujube (Ziziphus jujuba Mill.) Fruit in the Appetite Regulation Based on Network Pharmacology and Molecular Docking Method. PMID:35480085
Genetic susceptibility to patient-reported xerostomia among long-term oropharyngeal cancer survivors. PMID:35459784
Integrating Network Pharmacology and Molecular Docking Approaches to Decipher the Multi-Target Pharmacological Mechanism of Abrus precatorius L. Acting on Diabetes. PMID:35455411
Effects of Astragalus Polysaccharides on CD8+ Tissue-Resident Memory T Cells in Mice with Herpes Simplex. PMID:35388305
Da-Chai-Hu-Tang Protects From Acute Intrahepatic Cholestasis by Inhibiting Hepatic Inflammation and Bile Accumulation via Activation of PPARα. PMID:35370715
Elucidating the Synergistic Effect of Multiple Chinese Herbal Prescriptions in the Treatment of Post-stroke Neurological Damage. PMID:35355727
Protecting effect of emodin in experimental autoimmune encephalomyelitis mice by inhibiting microglia activation and inflammation via Myd88/PI3K/Akt/NF-κB signalling pathway. PMID:35287559
Prediction of the Active Components and Possible Targets of Xanthii Fructus Based on Network Pharmacology for Use in Chronic Rhinosinusitis. PMID:35287308
Identification of the potential mechanism of Radix pueraria in colon cancer based on network pharmacology. PMID:35260672
Inferring Retinal Degeneration-Related Genes Based on Xgboost. PMID:35223997
Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2. PMID:35179717
Protective Effects of the Wenfei Buqi Tongluo Formula on the Inflammation in Idiopathic Pulmonary Fibrosis through Inhibiting the TLR4/MyD88/NF-κB Pathway. PMID:35178456
Inferring Causation in Yeast Gene Association Networks With Kernel Logistic Regression. PMID:35173404
Network Pharmacology Analysis on the Mechanism of Huangqi Sijunzi Decoction in Treating Cancer-Related Fatigue. PMID:35154614
The mechanism of triptolide in the treatment of connective tissue disease-related interstitial lung disease based on network pharmacology and molecular docking. PMID:35132912
Proteomic landscape of SARS-CoV-2- and MERS-CoV-infected primary human renal epithelial cells. PMID:35110370
Elucidation of Potential Targets of San-Miao-San in the Treatment of Osteoarthritis Based on Network Pharmacology and Molecular Docking Analysis. PMID:35087596
Artificial Intelligence Analysis of Gene Expression Predicted the Overall Survival of Mantle Cell Lymphoma and a Large Pan-Cancer Series. PMID:35052318
Network-based prioritization of cancer biomarkers by phenotype-driven module detection and ranking. PMID:35024093
Comparative Gene Expression Analysis Reveals Similarities and Differences of Chronic Myeloid Leukemia Phases. PMID:35008420
Implication of proliferation gene biomarkers in pulmonary hypertension. PMID:34977488
Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 Infection. PMID:34975833
Mechanism of Elian granules in the treatment of precancerous lesions of gastric cancer in rats through the MAPK signalling pathway based on network pharmacology. PMID:34962453
In Vitro Study of Licorice on IL-1β-Induced Chondrocytes and In Silico Approach for Osteoarthritis. PMID:34959737
Integrated Metabolomics and Network Pharmacology to Establish the Action Mechanism of Qingrekasen Granule for Treating Nephrotic Syndrome. PMID:34938183
Revealing the Mechanism of Astragali Radix against Cancer-Related Fatigue by Network Pharmacology and Molecular Docking. PMID:34925533
Blood-Based Brain and Global Biomarker Changes after Combined Hypoxemia and Hemorrhagic Shock in a Rat Model of Penetrating Ballistic-Like Brain Injury. PMID:34901937
Computational Network Pharmacology-Based Strategy to Capture Key Functional Components and Decode the Mechanism of Chai-Hu-Shu-Gan-San in Treating Depression. PMID:34867413
The Pharmacological Mechanism of Guchangzhixie Capsule Against Experimental Colitis. PMID:34867387
Gene biomarker prediction in glioma by integrating scRNA-seq data and gene regulatory network. PMID:34863158
Insights into the SARS-CoV-2-Mediated Alteration in the Stress Granule Protein Regulatory Networks in Humans. PMID:34832615
In silico Methods for Identification of Potential Therapeutic Targets. PMID:34826045
A Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population. PMID:34815687
Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. PMID:34803695
Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets. PMID:34801852
Potential protective role of a NOD2 polymorphism in the susceptibility to multiple sclerosis is not associated with interferon therapy. PMID:34667597
Network Pharmacology-Based and Molecular Docking-Based Analysis of Suanzaoren Decoction for the Treatment of Parkinson's Disease with Sleep Disorder. PMID:34660782
Role of ferroptosis-related genes in Stanford type a aortic dissection and identification of key genes: new insights from bioinformatic analysis. PMID:34652258
The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis. PMID:34594156
Gene Expression Nebulas (GEN): a comprehensive data portal integrating transcriptomic profiles across multiple species at both bulk and single-cell levels. PMID:34591957
Evidence-based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease. PMID:34539848
Genomic variation in captive deer mouse (Peromyscus maniculatus) populations. PMID:34521341
Network pharmacology-based analysis in determining the mechanisms of Huoxin pill in protecting against myocardial infarction. PMID:34493157
A pan-cancer analysis of the prognostic and immunological role of β-actin (ACTB) in human cancers. PMID:34486492
Exploring the Biological Mechanism of Huang Yam in Treating Tumors and Preventing Antitumor Drug-Induced Cardiotoxicity Using Network Pharmacology and Molecular Docking Technology. PMID:34484411
Mechanism Prediction of Astragalus membranaceus against Cisplatin-Induced Kidney Damage by Network Pharmacology and Molecular Docking. PMID:34457031
Comparison and Analysis on the Existing Single-Herbal Strategies against Viral Myocarditis. PMID:34456633
Reveals of candidate active ingredients in Justicia and its anti-thrombotic action of mechanism based on network pharmacology approach and experimental validation. PMID:34433871
Identification of Potential Bioactive Ingredients and Mechanisms of the Guanxin Suhe Pill on Angina Pectoris by Integrating Network Pharmacology and Molecular Docking. PMID:34422068
Identification of COVID-19 and Dengue Host Factor Interaction Networks Based on Integrative Bioinformatics Analyses. PMID:34394108
Formononetin protects against ox-LDL-induced endothelial dysfunction by activating PPAR-γ signaling based on network pharmacology and experimental validation. PMID:34369277
A Novel Immune-Related lncRNA-Based Model for Survival Prediction in Clear Cell Renal Cell Carcinoma. PMID:34368371
A Novel Expression Signature from the Perspective of Mesenchymal-Epithelial Transition for Hepatocellular Carcinoma with Regard to Prognosis, Clinicopathological Features, Immune Cell Infiltration, Chemotherapeutic Efficacy, and Immunosuppressive Molecules. PMID:34367283
Role of Persistent Organic Pollutants in Breast Cancer Progression and Identification of Estrogen Receptor Alpha Inhibitors Using In-Silico Mining and Drug-Drug Interaction Network Approaches. PMID:34356536
Anti-Autophagy Mechanism of Zhi Gan Prescription Based on Network Pharmacology in Nonalcoholic Steatohepatitis Rats. PMID:34349657
Genome-wide CNV investigation suggests a role for cadherin, Wnt, and p53 pathways in primary open-angle glaucoma. PMID:34348663
Advances in the computational landscape for repurposed drugs against COVID-19. PMID:34339864
Bioinformatics Analysis: The Regulatory Network of hsa_circ_0007843 and hsa_circ_0007331 in Colon Cancer. PMID:34337040
The Potential Effect of Rhizoma coptidis on Polycystic Ovary Syndrome Based on Network Pharmacology and Molecular Docking. PMID:34306142
A Novel Computational Framework to Predict Disease-Related Copy Number Variations by Integrating Multiple Data Sources. PMID:34267783
Multi-target mechanism of Tripteryguim wilfordii Hook for treatment of ankylosing spondylitis based on network pharmacology and molecular docking. PMID:34259096
Angelica Dahurica Regulated the Polarization of Macrophages and Accelerated Wound Healing in Diabetes: A Network Pharmacology Study and In Vivo Experimental Validation. PMID:34234674
Bioinformatics integrated analysis to investigate candidate biomarkers and associated metabolites in osteosarcoma. PMID:34225733
Mechanism of protective effect of xuan-bai-cheng-qi decoction on LPS-induced acute lung injury based on an integrated network pharmacology and RNA-sequencing approach. PMID:34183011
Advancing clinical genomics and precision medicine with GVViZ: FAIR bioinformatics platform for variable gene-disease annotation, visualization, and expression analysis. PMID:34174938
UniBind: maps of high-confidence direct TF-DNA interactions across nine species. PMID:34174819
Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals. PMID:34155038
Network Pharmacology-Based Validation of the Efficacy of Huiyangjiuji Decoction in the Treatment of Experimental Colitis. PMID:34122086
Genome-wide DNA methylation analysis on C-reactive protein among Ghanaians suggests molecular links to the emerging risk of cardiovascular diseases. PMID:34117263
AnnotSV and knotAnnotSV: a web server for human structural variations annotations, ranking and analysis. PMID:34023905
Prognostic and clinicopathological insights of phosphodiesterase 9A gene as novel biomarker in human colorectal cancer. PMID:34016083
Comparative Analysis on Single- and Multiherb Strategies in Coronary Artery Atherosclerosis Therapy. PMID:34012683
Investigation of the Mechanism of Traditional Chinese Medicines in Angiogenesis through Network Pharmacology and Data Mining. PMID:34007289
Bioinformatics and system biology approaches to identify the diseasome and comorbidities complexities of SARS-CoV-2 infection with the digestive tract disorders. PMID:33993223
ETV4 and ETV5 drive synovial sarcoma through cell cycle and DUX4 embryonic pathway control. PMID:33983905
Pharmacological Mechanisms Underlying the Anti-asthmatic Effects of Modified Guomin Decoction Determined by Network Pharmacology and Molecular Docking. PMID:33968984
IBDDB: a manually curated and text-mining-enhanced database of genes involved in inflammatory bowel disease. PMID:33929018
CladeOScope: functional interactions through the prism of clade-wise co-evolution. PMID:33928243
GEE-TGDR: A Longitudinal Feature Selection Algorithm and Its Application to lncRNA Expression Profiles for Psoriasis Patients Treated with Immune Therapies. PMID:33928163
The Underlying Molecular Mechanisms Involved in Traditional Chinese Medicine Smilax china L. for the Treatment of Pelvic Inflammatory Disease. PMID:33927774
Computational and In Vitro Analysis of Plumbagin's Molecular Mechanism for the Treatment of Hepatocellular Carcinoma. PMID:33912033
Identification of the miRNA signature associated with survival in patients with ovarian cancer. PMID:33910165
Targeting the tumor stroma: integrative analysis reveal GATA2 and TORYAIP1 as novel prognostic targets in breast and ovarian cancer. PMID:33907495
DNA methylation as the link between migration and the major noncommunicable diseases: the RODAM study. PMID:33890479
An ensemble of the iCluster method to analyze longitudinal lncRNA expression data for psoriasis patients. PMID:33879268
The Use of Traditional Chinese Medicine in Relieving EGFR-TKI-Associated Diarrhea Based on Network Pharmacology and Data Mining. PMID:33868436
Chlorogenic Acid Inhibits Human Glioma U373 Cell Progression via Regulating the SRC/MAPKs Signal Pathway: Based on Network Pharmacology Analysis. PMID:33833498
Large Scale Molecular Studies of Pituitary Neuroendocrine Tumors: Novel Markers, Mechanisms and Translational Perspectives. PMID:33808624
DNA repair pathway activation features in follicular and papillary thyroid tumors, interrogated using 95 experimental RNA sequencing profiles. PMID:33748479
Synergistic Network Pharmacology for Traditional Chinese Medicine Liangxue Tongyu Formula in Acute Intracerebral Hemorrhagic Stroke. PMID:33727915
An Effective Hypoxia-Related Long Non-Coding RNAs Assessment Model for Prognosis of Clear Cell Renal Carcinoma. PMID:33692953
Mechanism of Modified Danggui Sini Decoction for Knee Osteoarthritis Based on Network Pharmacology and Molecular Docking. PMID:33628311
Uncovering the Anti-Lung-Cancer Mechanisms of the Herbal Drug FDY2004 by Network Pharmacology. PMID:33628308
A Network Pharmacology Study on the Molecular Mechanisms of FDY003 for Breast Cancer Treatment. PMID:33628298
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1. PMID:33628185
Gene expression barcode values reveal a potential link between Parkinson's disease and gastric cancer. PMID:33596182
A Network Pharmacology Approach to Estimate Potential Targets of the Active Ingredients of Epimedium for Alleviating Mild Cognitive Impairment and Treating Alzheimer's Disease. PMID:33574879
Understanding protein structural changes for oncogenic missense variants. PMID:33553733
Association of microbiota-derived propionic acid and Alzheimer's disease; bioinformatics analysis. PMID:33553012
Comparative Transcriptome Analysis During the Seven Developmental Stages of Channel Catfish (Ictalurus punctatus) and Tra Catfish (Pangasianodon hypophthalmus) Provides Novel Insights for Terrestrial Adaptation. PMID:33552125
An edge-based statistical analysis of long non-coding RNA expression profiles reveals a negative association between Parkinson's disease and colon cancer. PMID:33531021
A Study on the Therapeutic Efficacy of San Zi Yang Qin Decoction for Non-Alcoholic Fatty Liver Disease and the Underlying Mechanism Based on Network Pharmacology. PMID:33505505
SARS-CoV-2 and other human coronaviruses: Mapping of protease recognition sites, antigenic variation of spike protein and their grouping through molecular phylogenetics. PMID:33497837
Integrative computational approach identifies drug targets in CD4+ T-cell-mediated immune disorders. PMID:33483502
A Novel Strategy for Decoding and Validating the Combination Principles of Huanglian Jiedu Decoction From Multi-Scale Perspective. PMID:33424585
Clinical and Genetic Characteristics of Splicing Variant in CYP27A1 in an Iranian Family with Cerebrotendinous Xanthomatosis. PMID:33400472
An Investigation of the Molecular Mechanisms Underlying the Analgesic Effect of Jakyak-Gamcho Decoction: A Network Pharmacology Study. PMID:33343676
A Network Pharmacology Approach to Explore the Potential Mechanisms of Yifei Sanjie Formula in Treating Pulmonary Fibrosis. PMID:33335558
Identification of long non-coding RNA signatures for squamous cell carcinomas and adenocarcinomas. PMID:33318305
Mechanism of Action of Bu-Fei-Yi-Shen Formula in Treating Chronic Obstructive Pulmonary Disease Based on Network Pharmacology Analysis and Molecular Docking Validation. PMID:33313323
Exploring the Possible Mechanism and Drug Targets of Huang-Qi-Gui-Zhi-Wu-Wu Decoction for the Treatment of Chemotherapy-Induced Peripheral Neuropathy on Network Pharmacology. PMID:33299447
Study on Medication Rules of Traditional Chinese Medicine against Antineoplastic Drug-Induced Cardiotoxicity Based on Network Pharmacology and Data Mining. PMID:33281914
Informatics Inference of Exercise-Induced Modulation of Brain Pathways Based on Cerebrospinal Fluid Micro-RNAs in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. PMID:33274349
A Network Pharmacology-Based Strategy for Unveiling the Mechanisms of Tripterygium Wilfordii Hook F against Diabetic Kidney Disease. PMID:33274236
Deep whole-genome sequencing of multiple proband tissues and parental blood reveals the complex genetic etiology of congenital diaphragmatic hernias. PMID:33263113
HAHmiR.DB: a server platform for high-altitude human miRNA-gene coregulatory networks and associated regulatory circuits. PMID:33259604
Endocrine disrupting chemicals and COVID-19 relationships: A computational systems biology approach. PMID:33223326
Virtual screening and network pharmacology-based synergistic mechanism identification of multiple components contained in Guanxin V against coronary artery disease. PMID:33187508
Systematic Analysis of Protein-Protein and Gene-Environment Interactions to Decipher the Cognitive Mechanisms of Autism Spectrum Disorder. PMID:33165687
The transition from primary colorectal cancer to isolated peritoneal malignancy is associated with an increased tumour mutational burden. PMID:33144643
Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington's Disease Status Based on Omics Data. PMID:33049985
Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta. PMID:33046794
A Network Pharmacological Approach to Investigate the Mechanism of Action of Active Ingredients of Epimedii Herba and Their Potential Targets in Treatment of Alzheimer's Disease. PMID:32980851
Bio-activating ultrafine grain titanium: RNA sequencing reveals enhanced mechano-activation of osteoconduction on nanostructured substrates. PMID:32970688
Tobacco smoking induces metabolic reprogramming of renal cell carcinoma. PMID:32970633
A network pharmacology study on analgesic mechanism of Yuanhu-Baizhi herb pair. PMID:32948176
The Landscape of Micro-Inversions Provide Clues for Population Genetic Analysis of Humans. PMID:32929667
Variation in genes implicated in B-cell development and antibody production affects susceptibility to pemphigus. PMID:32926429
In-silico elucidation of Moringa oleifera phytochemicals against diabetes mellitus. PMID:32884411
Genomic Evidence for Sensorial Adaptations to a Nocturnal Predatory Lifestyle in Owls. PMID:32770228
Molecular Signatures and Networks of Cardiomyocyte Differentiation in Humans and Mice. PMID:32769060
A Novel Network Pharmacology Strategy to Decode Metabolic Biomarkers and Targets Interactions for Depression. PMID:32760300
Deep Transcriptomic Analysis Reveals the Dynamic Developmental Progression during Early Development of Channel Catfish (Ictalurus punctatus). PMID:32748829
(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A. PMID:32718059
Endocrine disrupting chemicals and COVID-19 relationships: a computational systems biology approach. PMID:32699854
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. PMID:32668255
Systems chemo-biology analysis of DNA damage response and cell cycle effects induced by coal exposure. PMID:32609278
Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs. PMID:32604718
Network Pharmacology-Based Identification of the Mechanisms of Shen-Qi Compound Formula in Treating Diabetes Mellitus. PMID:32595730
Mechanism of YuPingFeng in the Treatment of COPD Based on Network Pharmacology. PMID:32566658
Network Pharmacology and Experimental Evidence Reveal Dioscin Suppresses Proliferation, Invasion, and EMT via AKT/GSK3b/mTOR Signaling in Lung Adenocarcinoma. PMID:32546976
Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits. PMID:32542026
Detecting Prognosis Risk Biomarkers for Colon Cancer Through Multi-Omics-Based Prognostic Analysis and Target Regulation Simulation Modeling. PMID:32528533
An improved clear cell renal cell carcinoma stage prediction model based on gene sets. PMID:32513106
VIRdb: a comprehensive database for interactive analysis of genes/proteins involved in the pathogenesis of vitiligo. PMID:32509450
Human gene and disease associations for clinical-genomics and precision medicine research. PMID:32508008
Identification of genes and miRNA associated with idiopathic recurrent pregnancy loss: an exploratory data mining study. PMID:32487076
A transcriptome-based approach to identify functional modules within and across primary human immune cells. PMID:32469933
ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer. PMID:32454461
Uncovering the active compounds and effective mechanisms of the dried mature sarcocarp of Cornus officinalis Sieb. Et Zucc. For the treatment of Alzheimer's disease through a network pharmacology approach. PMID:32450873
Combinational approach of retrospective clinical evidence and transcriptomics highlight AMH superiority to FSH, as successful ICSI outcome predictor. PMID:32430730
High confidence copy number variants identified in Holstein dairy cattle from whole genome sequence and genotype array data. PMID:32415111
A Coupled Mathematical Model of the Intracellular Replication of Dengue Virus and the Host Cell Immune Response to Infection. PMID:32411105
MyoMiner: explore gene co-expression in normal and pathological muscle. PMID:32393257
Oviz-Bio: a web-based platform for interactive cancer genomics data visualization. PMID:32392343
Network Pharmacology Study of Heat-Clearing and Detoxifying Traditional Chinese Medicine for Alzheimer's Disease. PMID:32382304
RNA profiling identifies novel, photoperiod-history dependent markers associated with enhanced saltwater performance in juvenile Atlantic salmon. PMID:32267864
Systems Pharmacology-Based Strategy to Investigate Pharmacological Mechanisms of Radix Puerariae for Treatment of Hypertension. PMID:32265716
Feature selection based on differentially correlated gene pairs reveals the mechanism of IFN-β therapy for multiple sclerosis. PMID:32211244
Network-based computational approach to identify genetic links between cardiomyopathy and its risk factors. PMID:32196466
Selected neuropeptide genes show genetic differentiation between Africans and non-Africans. PMID:32171244
Network Pharmacology-Based Investigation of the System-Level Molecular Mechanisms of the Hematopoietic Activity of Samul-Tang, a Traditional Korean Herbal Formula. PMID:32104198
Network Pharmacology-Based Strategy to Investigate the Pharmacologic Mechanisms of Atractylodes macrocephala Koidz. for the Treatment of Chronic Gastritis. PMID:32063848
Exploring genetic targets of psoriasis using genome wide association studies (GWAS) for drug repurposing. PMID:31988837
MetaOmGraph: a workbench for interactive exploratory data analysis of large expression datasets. PMID:31956905
Identification of Monotonically Differentially Expressed Genes for IFN-β-Treated Multiple Sclerosis Patients. PMID:31915697
MOCHI enables discovery of heterogeneous interactome modules in 3D nucleome. PMID:31907193
Network Pharmacology Approach Reveals the Potential Immune Function Activation and Tumor Cell Apoptosis Promotion of Xia Qi Decoction in Lung Cancer. PMID:31905767
Multi-level transcriptome sequencing identifies COL1A1 as a candidate marker in human heart failure progression. PMID:31902369
PCA via joint graph Laplacian and sparse constraint: Identification of differentially expressed genes and sample clustering on gene expression data. PMID:31888433
DOCK5 regulates energy balance and hepatic insulin sensitivity by targeting mTORC1 signaling. PMID:31885214
MIRIA: a webserver for statistical, visual and meta-analysis of RNA editing data in mammals. PMID:31861975
Weighted gene expression profiles identify diagnostic and prognostic genes for lung adenocarcinoma and squamous cell carcinoma. PMID:31854219
Comparative Network Pharmacology Analysis of Classical TCM Prescriptions for Chronic Liver Disease. PMID:31824313
Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome. PMID:31796056
Biomarker identification of hepatocellular carcinoma using a methodical literature mining strategy. PMID:31725857
Differential regulatory network-based quantification and prioritization of key genes underlying cancer drug resistance based on time-course RNA-seq data. PMID:31682596
Network-based analysis of prostate cancer cell lines reveals novel marker gene candidates associated with radioresistance and patient relapse. PMID:31682594
Matching whole genomes to rare genetic disorders: Identification of potential causative variants using phenotype-weighted knowledge in the CAGI SickKids5 clinical genomes challenge. PMID:31680375
A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin. PMID:31660150
Debutant iOS app and gene-disease complexities in clinical genomics and precision medicine. PMID:31586224
Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease. PMID:31572720
Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line. PMID:31506438
Multi-view Subspace Clustering Analysis for Aggregating Multiple Heterogeneous Omics Data. PMID:31497031
Raptor genomes reveal evolutionary signatures of predatory and nocturnal lifestyles. PMID:31464627
Construction of subtype-specific prognostic gene signatures for early-stage non-small cell lung cancer using meta feature selection methods. PMID:31402939
Avian Binocularity and Adaptation to Nocturnal Environments: Genomic Insights from a Highly Derived Visual Phenotype. PMID:31386143
Bioactive Proteins in Channa striata Promote Wound Healing through Angiogenesis and Cell Proliferation. PMID:31362651
Analysis of gene expression in rheumatoid arthritis and related conditions offers insights into sex-bias, gene biotypes and co-expression patterns. PMID:31344123
Computational Biology Solutions to Identify Enhancers-target Gene Pairs. PMID:31316726
NBN Gene Analysis and it's Impact on Breast Cancer. PMID:31278556
In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR. PMID:31244651
Network-based prediction of polygenic disease genes involved in cell motility. PMID:31216978
Novel Acaricidal Drug Fluazuron Causes Immunotoxicity via Selective Depletion of Lymphocytes T CD8. PMID:31205477
Analysis of a Protein Network Related to Copy Number Variations in Autism Spectrum Disorder. PMID:31161481
BCR: a promiscuous fusion partner in hematopoietic disorders. PMID:31105873
SEanalysis: a web tool for super-enhancer associated regulatory analysis. PMID:31028388
Feature Selection for Longitudinal Data by Using Sign Averages to Summarize Gene Expression Values over Time. PMID:31016185
HumCFS: a database of fragile sites in human chromosomes. PMID:30999860
Identification of monotonically differentially expressed genes for non-small cell lung cancer. PMID:30971213
A Network-guided Association Mapping Approach from DNA Methylation to Disease. PMID:30944378
A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action of the Wei Pi Xiao Decoction for the Treatment of Gastric Precancerous Lesions. PMID:30854000
Biclustering analysis of transcriptome big data identifies condition-specific microRNA targets. PMID:30820547
Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs. PMID:30728774
Network Pharmacology Integrated Molecular Docking Reveals the Antiosteosarcoma Mechanism of Biochanin A. PMID:30723510
Generative modeling of multi-mapping reads with mHi-C advances analysis of Hi-C studies. PMID:30702424
HOPS-dependent endosomal fusion required for efficient cytosolic delivery of therapeutic peptides and small proteins. PMID:30610181
Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction. PMID:30608189
lncRNA-based study of epigenetic regulations in diabetic peripheral neuropathy. PMID:30607320
Co-differential Gene Selection and Clustering Based on Graph Regularized Multi-View NMF in Cancer Genomic Data. PMID:30487464
Genomes reveal marked differences in the adaptive evolution between orangutan species. PMID:30428903
piMGM: incorporating multi-source priors in mixed graphical models for learning disease networks. PMID:30423087
Association of Long-term Ambient Black Carbon Exposure and Oxidative Stress Allelic Variants With Intraocular Pressure in Older Men. PMID:30419128
The genetic prehistory of the Andean highlands 7000 years BP though European contact. PMID:30417096
Accelerated DNA methylation changes in middle-aged men define sexual dimorphism in human lifespans. PMID:30373676
SEdb: a comprehensive human super-enhancer database. PMID:30371817
CAGm: a repository of germline microsatellite variations in the 1000 genomes project. PMID:30329086
Network analysis of drug effect on triglyceride-associated DNA methylation. PMID:30275881
Proteomic analysis identifies highly expressed plasma membrane proteins for detection and therapeutic targeting of specific breast cancer subtypes. PMID:30250408
Identification of Biologically Essential Nodes via Determinative Power in Logical Models of Cellular Processes. PMID:30233390
Drug Repurposing of Metabolic Agents in Malignant Glioma. PMID:30223473
Parallel evolution and adaptation to environmental factors in a marine flatfish: Implications for fisheries and aquaculture management of the turbot (Scophthalmus maximus). PMID:30151043
Limited Evidence for Parallel Molecular Adaptations Associated with the Subterranean Niche in Mammals: A Comparative Study of Three Superorders. PMID:30137400
Synchronous birth is a dominant pattern in receptor-ligand evolution. PMID:30107779
Surgical and molecular characterization of primary and metastatic disease in a neuroendocrine tumor arising in a tailgut cyst. PMID:30087100
Using Multi-Scale Genetic, Neuroimaging and Clinical Data for Predicting Alzheimer's Disease and Reconstruction of Relevant Biological Mechanisms. PMID:30042519
Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective. PMID:30020984
Network-based association analysis to infer new disease-gene relationships using large-scale protein interactions. PMID:29949603
Platforms for Investigating LncRNA Functions. PMID:29945466
Genomewide association analyses of fitness traits in captive-reared Chinook salmon: Applications in evaluating conservation strategies. PMID:29928295
Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion. PMID:29890994
Predicting survival times for neuroblastoma patients using RNA-seq expression profiles. PMID:29848365
Network-Based Disease Module Discovery by a Novel Seed Connector Algorithm with Pathobiological Implications. PMID:29791871
In Silico Investigation of the Pharmacological Mechanisms of Beneficial Effects of Ginkgo biloba L. on Alzheimer's Disease. PMID:29747475
Genome-wide linkage analysis in Spanish melanoma-prone families identifies a new familial melanoma susceptibility locus at 11q. PMID:29706638
Massive mining of publicly available RNA-seq data from human and mouse. PMID:29636450
Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroups. PMID:29631562
Efficient pathway enrichment and network analysis of GWAS summary data using GSA-SNP2. PMID:29562348
Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer. PMID:29535384
A Novel Five-Node Feed-Forward Loop Unravels miRNA-Gene-TF Regulatory Relationships in Ischemic Stroke. PMID:29524052
A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission. PMID:29476864
MethCNA: a database for integrating genomic and epigenomic data in human cancer. PMID:29433427
miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila. PMID:29361610
Investigating the Mechanisms of Action of Depside Salt from Salvia miltiorrhiza Using Bioinformatic Analysis. PMID:29348768
Transcriptome profiling of peripheral blood immune cell populations in multiple sclerosis patients before and during treatment with a sphingosine-1-phosphate receptor modulator. PMID:29314605
Putative functional genes in idiopathic dilated cardiomyopathy. PMID:29311597
Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer. PMID:29295608
Obesity and obesogenic growth are both highly heritable and modified by diet in a nonhuman primate model, the African green monkey (Chlorocebus aethiops sabaeus). PMID:29211707
Comprehensive bioinformatics analysis of the characterization and determination underlying mechanisms of over-expression and co-expression of genes residing on 20q in colorectal cancer. PMID:29108255
Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding. PMID:29097687
A Systems Biology Approach Provides Deeper Insights into Differentially Expressed Genes in Taxane-Anthracycline Chemoresistant and Non-Resistant Breast Cancers. PMID:29072056
Lnc2Meth: a manually curated database of regulatory relationships between long non-coding RNAs and DNA methylation associated with human disease. PMID:29069510
Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score. PMID:28974751
Learning causal networks with latent variables from multivariate information in genomic data. PMID:28968390
Mutation-profile-based methods for understanding selection forces in cancer somatic mutations: a comparative analysis. PMID:28938601
Rational confederation of genes and diseases: NGS interpretation via GeneCards, MalaCards and VarElect. PMID:28830434
Cytokine Gene Polymorphisms Associated With Symptom Clusters in Oncology Patients Undergoing Radiation Therapy. PMID:28797847
Gene Expression Networks in the Murine Pulmonary Myocardium Provide Insight into the Pathobiology of Atrial Fibrillation. PMID:28720711
HDNetDB: A Molecular Interaction Database for Network-Oriented Investigations into Huntington's Disease. PMID:28701700
Differential co-expression analysis reveals a novel prognostic gene module in ovarian cancer. PMID:28694494
Genetic and epigenetic modifications in the pathogenesis of diabetic retinopathy: a molecular link to regulate gene expression. PMID:28691104
Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes. PMID:28606124
Network of microRNA, transcription factors, target genes and host genes in human mesothelioma. PMID:28587377
Biotinidase deficiency: Genotype-biochemical phenotype association in Brazilian patients. PMID:28498829
Editor's Highlight: Modifying Role of Endothelial Function Gene Variants on the Association of Long-Term PM2.5 Exposure With Blood DNA Methylation Age: The VA Normative Aging Study. PMID:28486674
Mining Exosomal Genes for Pancreatic Cancer Targets. PMID:28446531
Oncodomains: A protein domain-centric framework for analyzing rare variants in tumor samples. PMID:28426665
Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens. PMID:28415695
Connecting myelin-related and synaptic dysfunction in schizophrenia with SNP-rich gene expression hubs. PMID:28382934
Adaptation to infectious disease exposure in indigenous Southern African populations. PMID:28381615
Deconvolution of heterogeneous wound tissue samples into relative macrophage phenotype composition via models based on gene expression. PMID:28290581
Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. PMID:28150878
Both Maintenance and Avoidance of RNA-Binding Protein Interactions Constrain Coding Sequence Evolution. PMID:28138077
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures. PMID:28097054
Duplicates, redundancies and inconsistencies in the primary nucleotide databases: a descriptive study. PMID:28077566
Epigenetic sampling effects: nephrectomy modifies the clear cell renal cell cancer methylome. PMID:28074387
An analysis of disease-gene relationship from Medline abstracts by DigSee. PMID:28054646
Rare variant association test with multiple phenotypes. PMID:28039885
DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds. PMID:28032149
Comparing performance of non-tree-based and tree-based association mapping methods. PMID:27980669
Regulatory network of microRNAs and genes in testicular cancer. PMID:27900048
MalaCards: an amalgamated human disease compendium with diverse clinical and genetic annotation and structured search. PMID:27899610
Early pregnancy vitamin D status and risk of preeclampsia. PMID:27841759
Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved in Immunity and Neurogenesis in Simian Immunodeficiency Virus-Infected Macaques. PMID:27834864
Ten Simple Rules for Developing Public Biological Databases. PMID:27832061
Analysis of the interplay between methylation and expression reveals its potential role in cancer aetiology. PMID:27819121
Expression of myogenes in longissimus dorsi muscle during prenatal development in commercial and local Piau pigs. PMID:27801482
GenomeCRISPR - a database for high-throughput CRISPR/Cas9 screens. PMID:27789686
Methodology for single nucleotide polymorphism selection in promoter regions for clinical use. An example of its applicability. PMID:27766139
DenHunt - A Comprehensive Database of the Intricate Network of Dengue-Human Interactions. PMID:27618709
A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma. PMID:27563447
An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC). PMID:27556922
EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks. PMID:27556637
Family-based exome-wide assessment of maternal genetic effects on susceptibility to childhood B-cell acute lymphoblastic leukemia in hispanics. PMID:27529658
Genome-Wide Transcriptome and Binding Sites Analyses Identify Early FOX Expressions for Enhancing Cardiomyogenesis Efficiency of hESC Cultures. PMID:27501774
Characterization of BRCA1 and BRCA2 variants found in a Norwegian breast or ovarian cancer cohort. PMID:27495310
Prediction and Validation of Transcription Factors Modulating the Expression of Sestrin3 Gene Using an Integrated Computational and Experimental Approach. PMID:27466818
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins. PMID:27374120
VarElect: the phenotype-based variation prioritizer of the GeneCards Suite. PMID:27357693
Network analysis of microRNAs, transcription factors, target genes and host genes in human anaplastic astrocytoma. PMID:27347075
Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2. PMID:27337956
Network analysis of microRNAs, transcription factors, target genes and host genes in nasopharyngeal carcinoma. PMID:27313701
DREMECELS: A Curated Database for Base Excision and Mismatch Repair Mechanisms Associated Human Malignancies. PMID:27276067
Research Resources for Nuclear Receptor Signaling Pathways. PMID:27216565
Brucella melitensis and Mycobacterium tuberculosis depict overlapping gene expression patterns induced in infected THP-1 macrophages. PMID:27175205
PepPSy: a web server to prioritize gene products in experimental and biocuration workflows. PMID:27173522
Network and pathway analysis of microRNAs, transcription factors, target genes and host genes in human glioma. PMID:27123147
Significant Modules and Biological Processes between Active Components of Salvia miltiorrhiza Depside Salt and Aspirin. PMID:27069488
De novo deciphering three-dimensional chromatin interaction and topological domains by wavelet transformation of epigenetic profiles. PMID:27060148
Genic insights from integrated human proteomics in GeneCards. PMID:27048349
ITPI: Initial Transcription Process-Based Identification Method of Bioactive Components in Traditional Chinese Medicine Formula. PMID:27034696
Utilization of HPASubC for the Identification of Sinusoid-Specific Proteins in the Liver. PMID:27005832
CSCdb: a cancer stem cells portal for markers, related genes and functional information. PMID:26989154
GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data. PMID:26983021
The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development. PMID:26980699
A Human "eFP" Browser for Generating Gene Expression Anatograms. PMID:26954504
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. PMID:26871637
Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. PMID:26857140
Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans. PMID:26787651
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. PMID:26752265
Fine particles, genetic pathways, and markers of inflammation and endothelial dysfunction: Analysis on particulate species and sources. PMID:26732377
Construction and analysis of three networks of genes and microRNAs in adenocarcinoma. PMID:26722320
Effects of aging on circadian patterns of gene expression in the human prefrontal cortex. PMID:26699485
Systems Proteomics View of the Endogenous Human Claudin Protein Family. PMID:26680015
A computational method for drug repositioning using publicly available gene expression data. PMID:26679199
Taking Bioinformatics to Systems Medicine. PMID:26677177
microRNA and gene networks in human laryngeal cancer. PMID:26668624
Network analysis of microRNAs and genes in human osteosarcoma. PMID:26622516
Towards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond. PMID:26615025
Lynx: a knowledge base and an analytical workbench for integrative medicine. PMID:26590263
Mechanisms of Egg Yolk Formation and Implications on Early Life History of White Perch (Morone americana). PMID:26580971
SEA: a super-enhancer archive. PMID:26578594
PCOSKB: A KnowledgeBase on genes, diseases, ontology terms and biochemical pathways associated with PolyCystic Ovary Syndrome. PMID:26578565
GEneSTATION 1.0: a synthetic resource of diverse evolutionary and functional genomic data for studying the evolution of pregnancy-associated tissues and phenotypes. PMID:26567549
Graph-based unsupervised feature selection and multiview clustering for microarray data. PMID:26564977
Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment. PMID:26537877
Survey of Natural Language Processing Techniques in Bioinformatics. PMID:26525745
Bioinformatics Knowledge Map for Analysis of Beta-Catenin Function in Cancer. PMID:26509276
MicroRNA-derived network analysis of differentially methylated genes in schizophrenia, implicating GABA receptor B1 [GABBR1] and protein kinase B [AKT1]. PMID:26450699
dbSUPER: a database of super-enhancers in mouse and human genome. PMID:26438538
Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer. PMID:26427375
Integrative analysis of human protein, function and disease networks. PMID:26399914
Extracting tumor tissue immune status from expression profiles: correlating renal cancer prognosis with tumor-associated immunome. PMID:26384298
Positive selection of AS3MT to arsenic water in Andean populations. PMID:26366667
miRTarVis: an interactive visual analysis tool for microRNA-mRNA expression profile data. PMID:26361498
Identification of Aberrant Chromosomal Regions in Human Breast Cancer Using Gene Expression Data and Related Gene Information. PMID:26319982
Integrating Gene Regulatory Networks to identify cancer-specific genes. PMID:26306224
DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection. PMID:26292806
A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function. PMID:26231201
Common polygenic variation contributes to risk of migraine in the Norfolk Island population. PMID:26220684
An Enriched European Eel Transcriptome Sheds Light upon Host-Pathogen Interactions with Vibrio vulnificus. PMID:26207370
Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps. PMID:26192618
Phenolyzer: phenotype-based prioritization of candidate genes for human diseases. PMID:26192085
Identification of Ohnolog Genes Originating from Whole Genome Duplication in Early Vertebrates, Based on Synteny Comparison across Multiple Genomes. PMID:26181593
Enrichment of the Cancer Stem Phenotype in Sphere Cultures of Prostate Cancer Cell Lines Occurs through Activation of Developmental Pathways Mediated by the Transcriptional Regulator ΔNp63α. PMID:26110651
ABCG2 is a potential marker of tumor-initiating cells in breast cancer. PMID:26091795
Stress-induced DNA damage biomarkers: applications and limitations. PMID:26082923
Advances in long noncoding RNAs: identification, structure prediction and function annotation. PMID:26072035
PADPIN: protein-protein interaction networks of angiogenesis, arteriogenesis, and inflammation in peripheral arterial disease. PMID:26058837
The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain. PMID:26052355
ComiRNet: a web-based system for the analysis of miRNA-gene regulatory networks. PMID:26051695
Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting. PMID:26027894
ProteINSIDE to Easily Investigate Proteomics Data from Ruminants: Application to Mine Proteome of Adipose and Muscle Tissues in Bovine Foetuses. PMID:26000831
PALM-IST: Pathway Assembly from Literature Mining--an Information Search Tool. PMID:25989388
RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells. PMID:25858977
Conservation of pro-longevity genes among mammals. PMID:25804384
A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes. PMID:25793257
Population analysis of microsatellite genotypes reveals a signature associated with ovarian cancer. PMID:25779658
Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population. PMID:25772781
Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions. PMID:25755260
PathCards: multi-source consolidation of human biological pathways. PMID:25725062
BicPAM: Pattern-based biclustering for biomedical data analysis. PMID:25649207
An efficient and comprehensive strategy for genetic diagnostics of polycystic kidney disease. PMID:25646624
Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity. PMID:25587033
LinkRbrain: multi-scale data integrator of the brain. PMID:25528112
Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas. PMID:25521819
SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation. PMID:25484892
Computational strategies for a system-level understanding of metabolism. PMID:25427076
Human ALDH1B1 polymorphisms may affect the metabolism of acetaldehyde and all-trans retinaldehyde--in vitro studies and computational modeling. PMID:25413692
A pan-cancer modular regulatory network analysis to identify common and cancer-specific network components. PMID:25374456
Genenames.org: the HGNC resources in 2015. PMID:25361968
STRING v10: protein-protein interaction networks, integrated over the tree of life. PMID:25352553
MicroRNA and gene networks in human diffuse large B-cell lymphoma. PMID:25289101
Proteomic study reveals a functional network of cancer markers in the G1-Stage of the breast cancer cell cycle. PMID:25252636
Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress? PMID:25238782
Discovery and validation of new potential biomarkers for early detection of colon cancer. PMID:25215506
A quantitative transcriptome reference map of the normal human brain. PMID:25185649
Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. PMID:25173105
Making proteomics data accessible and reusable: current state of proteomics databases and repositories. PMID:25158685
Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites. PMID:25106527
WI-38 senescence is associated with global and site-specific hypomethylation. PMID:25063771
A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts. PMID:25063769
PubServer: literature searches by homology. PMID:24957597
Construction and analysis of regulatory genetic networks in cervical cancer based on involved microRNAs, target genes, transcription factors and host genes. PMID:24944708
Microsatellite genotyping reveals a signature in breast cancer exomes. PMID:24838940
Fetal alcohol syndrome, chemo-biology and OMICS: ethanol effects on vitamin metabolism during neurodevelopment as measured by systems biology analysis. PMID:24816220
OncoSearch: cancer gene search engine with literature evidence. PMID:24813447
SwissTargetPrediction: a web server for target prediction of bioactive small molecules. PMID:24792161
BioTCM-SE: a semantic search engine for the information retrieval of modern biology and traditional Chinese medicine. PMID:24772189
A novel genetic score approach using instruments to investigate interactions between pathways and environment: application to air pollution. PMID:24755831
Unraveling human protein interaction networks underlying co-occurrences of diseases and pathological conditions. PMID:24731539
Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension. PMID:24702692
Identification of odorant-receptor interactions by global mapping of the human odorome. PMID:24695519
Finding alternative expression quantitative trait loci by exploring sparse model space. PMID:24689773
Bovine exome sequence analysis and targeted SNP genotyping of recessive fertility defects BH1, HH2, and HH3 reveal a putative causative mutation in SMC2 for HH3. PMID:24667746
GeneSense: a new approach for human gene annotation integrated with protein-protein interaction networks. PMID:24667292
ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration. PMID:24618899
Cancer evolution is associated with pervasive positive selection on globally expressed genes. PMID:24603726
Integrating microRNA target predictions for the discovery of gene regulatory networks: a semi-supervised ensemble learning approach. PMID:24564296
Genomic characterization of three urinary bladder cancer cell lines: understanding genomic types of urinary bladder cancer. PMID:24459064
Whole genome sequence of a Turkish individual. PMID:24416366
Histone deacetylase inhibitors potentiate vesicular stomatitis virus oncolysis in prostate cancer cells by modulating NF-κB-dependent autophagy. PMID:24371063
RefPrimeCouch--a reference gene primer CouchApp. PMID:24368831
The Reactome pathway knowledgebase. PMID:24243840
UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks. PMID:24214987
Targeted deletion of the gene encoding the La autoantigen (Sjögren's syndrome antigen B) in B cells or the frontal brain causes extensive tissue loss. PMID:24190965
HypoxiaDB: a database of hypoxia-regulated proteins. PMID:24178989
Characterization of regulatory features of housekeeping and tissue-specific regulators within tissue regulatory networks. PMID:24172660
SIMAP--the database of all-against-all protein sequence similarities and annotations with new interfaces and increased coverage. PMID:24165881
Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs. PMID:24151501
microRNA and gene networks in human pancreatic cancer. PMID:24137477
Identification of 526 conserved metazoan genetic innovations exposes a new role for cofactor E-like in neuronal microtubule homeostasis. PMID:24098140
A computational approach to chemical etiologies of diabetes. PMID:24048418
The human urine metabolome. PMID:24023812
A literature search tool for intelligent extraction of disease-associated genes. PMID:23999671
PhenoTimer: software for the visual mapping of time-resolved phenotypic landscapes. PMID:23951317
Variants in exons and in transcription factors affect gene expression in trans. PMID:23844908
Integrating pathways of Parkinson's disease in a molecular interaction map. PMID:23832570
DigSee: Disease gene search engine with evidence sentences (version cancer). PMID:23761452
Comparison of modules of wild type and mutant Huntingtin and TP53 protein interaction networks: implications in biological processes and functions. PMID:23741403
The influence of 13-cis retinoic acid on human meibomian gland epithelial cells. PMID:23722388
Microarray analyses reveal novel targets of exercise-induced stress resistance in the dorsal raphe nucleus. PMID:23717271
Toxicological effects of the different substances in tobacco smoke on human embryonic development by a systems chemo-biology approach. PMID:23637898
Interferon-beta therapy in multiple sclerosis: the short-term and long-term effects on the patients' individual gene expression in peripheral blood. PMID:23636981
MalaCards: an integrated compendium for diseases and their annotation. PMID:23584832
Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts: implications for pathogenesis. PMID:23575763
Dynamic regulation of epigenomic landscapes during hematopoiesis. PMID:23510235
Canonical correlation analysis for RNA-seq co-expression networks. PMID:23460206
GABBR1 has a HERV-W LTR in its regulatory region--a possible implication for schizophrenia. PMID:23391219
Identification and comparative analysis of ncRNAs in human, mouse and zebrafish indicate a conserved role in regulation of genes expressed in brain. PMID:23284966
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17. PMID:23259914
Gene family matters: expanding the HGNC resource. PMID:23245209
The evolution of ultraconserved elements with different phylogenetic origins. PMID:23217155
The TissueNet database of human tissue protein-protein interactions. PMID:23193266
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. PMID:23177736
Genenames.org: the HGNC resources in 2013. PMID:23161694
Proteomic snapshot of breast cancer cell cycle: G1/S transition point. PMID:23152136
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis. PMID:23143109
The expanding role of MBD genes in autism: identification of a MECP2 duplication and novel alterations in MBD5, MBD6, and SETDB1. PMID:23055267
Positive-unlabeled learning for disease gene identification. PMID:22923290
Personal receptor repertoires: olfaction as a model. PMID:22908908
Screening of candidate genes for primary open angle glaucoma. PMID:22876139
Progression of mouse skin carcinogenesis is associated with increased ERα levels and is repressed by a dominant negative form of ERα. PMID:22870269
A natural language interface plug-in for cooperative query answering in biological databases. PMID:22759613
Empirical Bayes conditional independence graphs for regulatory network recovery. PMID:22685074
Relax with CouchDB--into the non-relational DBMS era of bioinformatics. PMID:22609849
Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity. PMID:22595969
Regulatory Snapshots: integrative mining of regulatory modules from expression time series and regulatory networks. PMID:22563474
Very small embryonic-like stem cells purified from umbilical cord blood lack stem cell characteristics. PMID:22509366
Pan-genomic analysis of bovine monocyte-derived macrophage gene expression in response to in vitro infection with Mycobacterium avium subspecies paratuberculosis. PMID:22455317
Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis. PMID:22384131
IntegromeDB: an integrated system and biological search engine. PMID:22260095
Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers. PMID:22253144
Global gene expression analysis of the interaction between cancer cells and osteoblasts to predict bone metastasis in breast cancer. PMID:22235336
Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes. PMID:22182502
In-silico human genomics with GeneCards. PMID:22155609
MOPED: Model Organism Protein Expression Database. PMID:22139914
Identification of dysfunctional modules and disease genes in congenital heart disease by a network-based approach. PMID:22136190
DNAtraffic--a new database for systems biology of DNA dynamics during the cell life. PMID:22110027
Databases and bioinformatics tools for the study of DNA repair. PMID:22091405
canSAR: an integrated cancer public translational research and drug discovery resource. PMID:22013161
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. PMID:21998308
Comparative analysis of neural transcriptomes and functional implication of unannotated intronic expression. PMID:21985610
The UCSC Genome Browser. PMID:21975940
PATRIC: the comprehensive bacterial bioinformatics resource with a focus on human pathogenic species. PMID:21896772
Cancer testis antigens in newly diagnosed and relapse multiple myeloma: prognostic markers and potential targets for immunotherapy. PMID:21791470
RASOnD-a comprehensive resource and search tool for RAS superfamily oncogenes from various species. PMID:21729256
Exploiting Statistical Methodologies and Controlled Vocabularies for Prioritized Functional Analysis of Genomic Experiments: the StRAnGER Web Application. PMID:21293737
DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. PMID:21059682
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. PMID:21045058
DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle. PMID:20942903
genenames.org: the HGNC resources in 2011. PMID:20929869
GeneCards: integrating information about genes, proteins and diseases PubMed citations: 226.

226 articles citing: GeneCards: integrating information about genes, proteins and diseases

Network Pharmacology and Molecular Docking on the Molecular Mechanism of Jiawei-Huang Lian-Gan Jiang Decoction in the Treatment of Colorectal Adenomas. PMID:35899228
A review on computational approaches that support the researches on traditional Chinese medicines (TCM) against COVID-19. PMID:35841663
Network Pharmacology Experiments Show That Emodin Can Exert a Protective Effect on MCAO Rats by Regulating Hif-1α/VEGF-A Signaling. PMID:35811865
Modeling Kaempferol as a Potential Pharmacological Agent for COVID-19/PF Co-Occurrence Based on Bioinformatics and System Pharmacological Tools. PMID:35754492
Development of a Machine Learning Model to Predict Non-Durable Response to Anti-TNF Therapy in Crohn's Disease Using Transcriptome Imputed from Genotypes. PMID:35743732
Network Pharmacology and In Vivo Experimental Validation to Uncover the Renoprotective Mechanisms of Fangji Huangqi Decoction on Nephrotic Syndrome. PMID:35722158
Exploring the Structural and Functional Effects of Nonsynonymous SNPs in the Human Serotonin Transporter Gene Through In Silico Approaches. PMID:35706533
Network pharmacology and molecular docking approach to elucidate the mechanisms of Liuwei Dihuang pill in diabetic osteoporosis. PMID:35701780
Mechanisms of Quercetin against atrial fibrillation explored by network pharmacology combined with molecular docking and experimental validation. PMID:35697725
Licoflavone A Suppresses Gastric Cancer Growth and Metastasis by Blocking the VEGFR-2 Signaling Pathway. PMID:35509849
Identification of HMOX1 as a Critical Ferroptosis-Related Gene in Atherosclerosis. PMID:35498043
Systematic Elaboration of the Pharmacological Targets and Potential Mechanisms of ZhiKe GanCao Decoction for Preventing and Delaying Intervertebral Disc Degeneration. PMID:35497916
Novel approach by natural language processing for COVID-19 knowledge discovery. PMID:35367669
Inspiration for COVID-19 Treatment: Network Analysis and Experimental Validation of Baicalin for Cytokine Storm. PMID:35350754
Understanding the activating mechanism of the immune system against COVID-19 by Traditional Indian Medicine: Network pharmacology approach. PMID:35305722
DBHR: a collection of databases relevant to human research. PMID:35251694
[Identification of traditional Chinese drugs containing active ingredients for treating myocardial infarction and analysis of their therapeutic mechanisms by network pharmacology and molecular docking]. PMID:35249866
An Integrated Pharmacology-Based Strategy to Investigate the Potential Mechanism of Xiebai San in Treating Pediatric Pneumonia. PMID:35237157
Herbal Formula Modified Bu-Shen-Huo-Xue Decoction Attenuates Intervertebral Disc Degeneration via Regulating Inflammation and Oxidative Stress. PMID:35154344
Network Pharmacology and Molecular Docking Analysis on Pharmacological Mechanisms of Astragalus membranaceus in the Treatment of Gastric Ulcer. PMID:35140802
Network pharmacology-based strategy to investigate the active ingredients and molecular mechanisms of Scutellaria Barbata D. Don against radiation pneumonitis. PMID:34964782
Mechanism of Elian granules in the treatment of precancerous lesions of gastric cancer in rats through the MAPK signalling pathway based on network pharmacology. PMID:34962453
The Pharmacological Mechanism of Guchangzhixie Capsule Against Experimental Colitis. PMID:34867387
The possible mechanism of Hippophae fructus oil applied in tympanic membrane repair identified based on network pharmacology and molecular docking. PMID:34859918
Identification of the Active Constituents and Significant Pathways of Shen-qi-Yi-zhu Decoction on Antigastric Cancer: A Network Pharmacology Research and Experimental Validation. PMID:34853601
Network Pharmacology Exploration Reveals Anti-Apoptosis as a Common Therapeutic Mechanism for Non-Alcoholic Fatty Liver Disease Treated with Blueberry Leaf Polyphenols. PMID:34836315
Pharmacological Mechanism of Danggui-Sini Formula for Intervertebral Disc Degeneration: A Network Pharmacology Study. PMID:34805401
Mechanistic insights into the renoprotective role of curcumin in cisplatin-induced acute kidney injury: network pharmacology analysis and experimental validation. PMID:34802380
Genome-wide association study of hospitalized COVID-19 patients in the United Arab Emirates. PMID:34775353
Narrative online guides for the interpretation of digital-pathology images and tissue-atlas data. PMID:34750536
Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling. PMID:34643103
Indigenous Ancestry and Admixture in the Uruguayan Population. PMID:34630523
[Exploring the therapeutic mechanism of quercetin for heart failure based on network pharmacology and molecular docking]. PMID:34549711
New Insights Into Mitochondrial Dysfunction at Disease Susceptibility Loci in the Development of Type 2 Diabetes. PMID:34456865
A propagation-based seed-centric local community detection for multilayer environment: The case study of colon adenocarcinoma. PMID:34370784
Network Pharmacology-Based Validation of the Efficacy of Huiyangjiuji Decoction in the Treatment of Experimental Colitis. PMID:34122086
Investigating the active compounds and mechanism of HuaShi XuanFei formula for prevention and treatment of COVID-19 based on network pharmacology and molecular docking analysis. PMID:34105049
Knowledge bases and software support for variant interpretation in precision oncology. PMID:33971666
A network pharmacology based approach for predicting active ingredients and potential mechanism of Lianhuaqingwen capsule in treating COVID-19. PMID:33746604
A comprehensive molecular characterization of the 8q22.2 region reveals the prognostic relevance of OSR2 mRNA in muscle invasive bladder cancer. PMID:33711044
rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis. PMID:33633225
Association of microbiota-derived propionic acid and Alzheimer's disease; bioinformatics analysis. PMID:33553012
Potential effect of Maxing Shigan decoction against coronavirus disease 2019 (COVID-19) revealed by network pharmacology and experimental verification. PMID:33513419
Exploring the treatment of COVID-19 with Yinqiao powder based on network pharmacology. PMID:33452734
Quercetin as a potential treatment for COVID-19-induced acute kidney injury: Based on network pharmacology and molecular docking study. PMID:33444408
Uncovering the mechanism of Ge-Gen-Qin-Lian decoction for treating ulcerative colitis based on network pharmacology and molecular docking verification. PMID:33409535
Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID-19. PMID:33140889
Genetic architecture and genomic selection of female reproduction traits in rainbow trout. PMID:32795250
Systems chemo-biology analysis of DNA damage response and cell cycle effects induced by coal exposure. PMID:32609278
Network Pharmacology-Based Identification of the Mechanisms of Shen-Qi Compound Formula in Treating Diabetes Mellitus. PMID:32595730
Epigenome-Wide Tobacco-Related Methylation Signature Identification and Their Multilevel Regulatory Network Inference for Lung Adenocarcinoma. PMID:32420331
Systems Pharmacology-Based Strategy to Investigate Pharmacological Mechanisms of Radix Puerariae for Treatment of Hypertension. PMID:32265716
Time course regulatory analysis based on paired expression and chromatin accessibility data. PMID:32188700
Identification of the Active Constituents and Significant Pathways of Cangfu Daotan Decoction for the Treatment of PCOS Based on Network Pharmacology. PMID:32148541
Multiple Pathways Involved in Palmitic Acid-Induced Toxicity: A System Biology Approach. PMID:32076395
Network Pharmacology-Based Strategy to Investigate the Pharmacologic Mechanisms of Atractylodes macrocephala Koidz. for the Treatment of Chronic Gastritis. PMID:32063848
How to Illuminate the Druggable Genome Using Pharos. PMID:31898878
DNA methylation directs microRNA biogenesis in mammalian cells. PMID:31827083
Multivariable regulation of gene expression plasticity in metazoans. PMID:31795914
Twenty Years of "Lipid World": A Fertile Partnership with David Deamer. PMID:31547028
Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress-related damage in the murine retina. PMID:31527661
GPT2 mutations in autosomal recessive developmental disability: extending the clinical phenotype and population prevalence estimates. PMID:31471722
Genome-Wide Association Study of Metabolic Syndrome Reveals Primary Genetic Variants at CETP Locus in Indians. PMID:31366177
VariED: the first integrated database of gene annotation and expression profiles for variants related to human diseases. PMID:31317185
GAIL: An interactive webserver for inference and dynamic visualization of gene-gene associations based on gene ontology guided mining of biomedical literature. PMID:31260503
Differences in the fast muscle methylome provide insight into sex-specific epigenetic regulation of growth in Nile tilapia during early stages of domestication. PMID:31131688
Transcriptome Analysis Reveals Novel Genes Associated with Cartilage Degeneration in Posttraumatic Osteoarthritis Progression. PMID:31104480
anamiR: integrated analysis of MicroRNA and gene expression profiling. PMID:31088348
Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name. PMID:31071451
Phenotypic subgrouping and multi-omics analyses reveal reduced diazepam-binding inhibitor (DBI) protein levels in autism spectrum disorder with severe language impairment. PMID:30921354
Effects of early social deprivation on epigenetic statuses and adaptive behavior of young children: A study based on a cohort of institutionalized infants and toddlers. PMID:30913238
Genome-wide association study of blood lipids in Indians confirms universality of established variants. PMID:30911093
A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action of the Wei Pi Xiao Decoction for the Treatment of Gastric Precancerous Lesions. PMID:30854000
POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33. PMID:30643196
Admixture Effects on Coevolved Metabolic Systems. PMID:30619461
Preoperative Metabolic Tumor Volume2.5 Associated with Early Systemic Metastasis in Resected Pancreatic Cancer: A Transcriptome-Wide Analysis. PMID:30602217
NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants. PMID:30528300
Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report. PMID:30467200
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances. PMID:30371672
The master regulator FUBP1: its emerging role in normal cell function and malignant development. PMID:30343319
The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells. PMID:30253781
Detecting long non-coding RNA biomarkers in prostate cancer liquid biopsies: Hype or hope? PMID:30159441
Exploring the Role of Fallopian Ciliated Cells in the Pathogenesis of High-Grade Serous Ovarian Cancer. PMID:30149579
Thyroid cancers of follicular origin in a genomic light: in-depth overview of common and unique molecular marker candidates. PMID:30089490
NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor. PMID:29895898
Understanding the seminal plasma proteome and its role in male fertility. PMID:29881623
MGOGP: a gene module-based heuristic algorithm for cancer-related gene prioritization. PMID:29871590
Genome-wide prediction of cis-regulatory regions using supervised deep learning methods. PMID:29855387
Transcription Factor Co-expression Networks of Adipose RNA-Seq Data Reveal Regulatory Mechanisms of Obesity. PMID:29755291
ENTPRISE-X: Predicting disease-associated frameshift and nonsense mutations. PMID:29723276
One for all and all for One: Improving replication of genetic studies through network diffusion. PMID:29684019
Rare variants in drug target genes contributing to complex diseases, phenome-wide. PMID:29545597
Double agents: genes with both oncogenic and tumor-suppressor functions. PMID:29540752
Protein complex finding and ranking: An application to Alzheimer's disease. PMID:29358552
Lessons from ten years of genome-wide association studies of asthma. PMID:29333270
Granatum: a graphical single-cell RNA-Seq analysis pipeline for genomics scientists. PMID:29202807
Identification of cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers. PMID:29126163
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. PMID:29083406
Epigenome alterations in aortic valve stenosis and its related left ventricular hypertrophy. PMID:29026447
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. PMID:28957414
miR-217-5p induces apoptosis by directly targeting PRKCI, BAG3, ITGAV and MAPK1 in colorectal cancer cells. PMID:28905214
A genome-wide association study identifies genomic loci associated with backfat thickness, carcass weight, and body weight in two commercial pig populations. PMID:28890999
Integrated Computational Analysis of Genes Associated with Human Hereditary Insensitivity to Pain. A Drug Repurposing Perspective. PMID:28848388
Genome-Scale Modeling of NADPH-Driven β-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma. PMID:28762750
Prognostic value of ion channel genes in Chinese patients with gliomas based on mRNA expression profiling. PMID:28752501
Next-generation sequencing of the human TRPV1 gene and the regulating co-players LTB4R and LTB4R2 based on a custom AmpliSeq™ panel. PMID:28658281
NaviSE: superenhancer navigator integrating epigenomics signal algebra. PMID:28587674
Radiation induced pulmonary fibrosis as a model of progressive fibrosis: Contributions of DNA damage, inflammatory response and cellular senescence genes. PMID:28534660
De Novo Coding Variants Are Strongly Associated with Tourette Disorder. PMID:28472652
Disease biomarker identification from gene network modules for metastasized breast cancer. PMID:28432361
Bioinformatics Analysis Reveals Genes Involved in the Pathogenesis of Ameloblastoma and Keratocystic Odontogenic Tumor. PMID:28357197
FocusHeuristics - expression-data-driven network optimization and disease gene prediction. PMID:28205611
Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases. PMID:27923045
A three ion channel genes-based signature predicts prognosis of primary glioblastoma patients and reveals a chemotherapy sensitive subtype. PMID:27713134
Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants. PMID:27690223
Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth. PMID:27664809
Complex Sources of Variation in Tissue Expression Data: Analysis of the GTEx Lung Transcriptome. PMID:27588449
Elucidating tissue specific genes using the Benford distribution. PMID:27506195
VarElect: the phenotype-based variation prioritizer of the GeneCards Suite. PMID:27357693
RASSF1A Site-Specific Methylation Hotspots in Cancer and Correlation with RASSF1C and MOAP-1. PMID:27294960
Purifying selection shapes the coincident SNP distribution of primate coding sequences. PMID:27255481
Analysis of the dynamic co-expression network of heart regeneration in the zebrafish. PMID:27241320
Building a glaucoma interaction network using a text mining approach. PMID:27152122
A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer. PMID:27067391
Bioinformatic exploration of MTA1-regulated gene networks in colon cancer. PMID:27052252
Multivariate models from RNA-Seq SNVs yield candidate molecular targets for biomarker discovery: SNV-DA. PMID:27029813
Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. PMID:27015805
DASPfind: new efficient method to predict drug-target interactions. PMID:26985240
GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data. PMID:26983021
ENTPRISE: An Algorithm for Predicting Human Disease-Associated Amino Acid Substitutions from Sequence Entropy and Predicted Protein Structures. PMID:26982818
Testing for association between RNA-Seq and high-dimensional data. PMID:26951498
Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing. PMID:26929214
LENS: web-based lens for enrichment and network studies of human proteins. PMID:26680011
Integrative enrichment analysis: a new computational method to detect dysregulated pathways in heterogeneous samples. PMID:26556243
Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. PMID:26487704
PUBLIC HEALTH AND EPIDEMIOLOGICAL DATABASES FOR THE ENHANCEMENT OF MEDICAL EDUCATION. PMID:26392847
Understanding the aristolochic acid toxicities in rat kidneys with regulatory networks. PMID:26243830
Identify asthma genes across three phases based on protein-protein interaction network. PMID:26243829
Connecting SNPs in Diabetes: A Spatial Analysis of Meta-GWAS Loci. PMID:26191039
Transcriptional Perturbations in Graft Rejection. PMID:26154388
Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. PMID:26064958
Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population. PMID:25880194
A comparative study of improvements Pre-filter methods bring on feature selection using microarray data. PMID:25825671
CCAAT/enhancer binding protein β in relation to ER stress, inflammation, and metabolic disturbances. PMID:25699273
Impulsivity and comorbid traits: a multi-step approach for finding putative responsible microRNAs in the amygdala. PMID:25561905
Casein kinase II inhibitor enhances production of infectious genotype 1a hepatitis C virus (H77S). PMID:25464014
The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease. PMID:25402615
Genetic variation in imprinted genes is associated with risk of late-onset Alzheimer's disease. PMID:25391383
Current advances in systems and integrative biology. PMID:25379142
Disease-targeted sequencing of ion channel genes identifies de novo mutations in patients with non-familial Brugada syndrome. PMID:25339316
Expression profiling of mitochondrial voltage-dependent anion channel-1 associated genes predicts recurrence-free survival in human carcinomas. PMID:25333947
Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging. PMID:25329999
Drosophila COP9 signalosome subunit 7 interacts with multiple genomic loci to regulate development. PMID:25106867
Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns. PMID:25006744
piRNAQuest: searching the piRNAome for silencers. PMID:24997126
Identification of novel elements of the Drosophila blisterome sheds light on potential pathological mechanisms of several human diseases. PMID:24968325
MOPED 2.5--an integrated multi-omics resource: multi-omics profiling expression database now includes transcriptomics data. PMID:24910945
Quantitative temporal viromics: an approach to investigate host-pathogen interaction. PMID:24906157
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM. PMID:24874098
Ovary transcriptome profiling via artificial intelligence reveals a transcriptomic fingerprint predicting egg quality in striped bass, Morone saxatilis. PMID:24820964
Fetal alcohol syndrome, chemo-biology and OMICS: ethanol effects on vitamin metabolism during neurodevelopment as measured by systems biology analysis. PMID:24816220
Connecting the dots: potential of data integration to identify regulatory SNPs in late-onset Alzheimer's disease GWAS findings. PMID:24743338
The application of network label propagation to rank biomarkers in genome-wide Alzheimer's data. PMID:24731236
Genes influenced by the non-muscle isoform of Myosin light chain kinase impact human cancer prognosis. PMID:24714365
Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia. PMID:24681604
Ion channel gene expression in lung adenocarcinoma: potential role in prognosis and diagnosis. PMID:24466154
Review of biological network data and its applications. PMID:24465231
A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. PMID:24430173
Systems biology approach to stage-wise characterization of epigenetic genes in lung adenocarcinoma. PMID:24369052
MOPED enables discoveries through consistently processed proteomics data. PMID:24350770
Wnt signaling and the control of human stem cell fate. PMID:24323281
Transcriptome analysis of Nautilus and pygmy squid developing eye provides insights in lens and eye evolution. PMID:24205087
Expression profiling of ion channel genes predicts clinical outcome in breast cancer. PMID:24053408
Proteome mapping of adult zebrafish marrow neutrophils reveals partial cross species conservation to human peripheral neutrophils. PMID:24019943
Evaluation of 41 candidate gene variants for obesity in the EPIC-Potsdam cohort by multi-locus stepwise regression. PMID:23874820
Toxicological effects of the different substances in tobacco smoke on human embryonic development by a systems chemo-biology approach. PMID:23637898
Chapter 15: disease gene prioritization. PMID:23633938
Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors. PMID:23618374
A powerful and efficient set test for genetic markers that handles confounders. PMID:23599503
GPR158, an orphan member of G protein-coupled receptor Family C: glucocorticoid-stimulated expression and novel nuclear role. PMID:23451275
SNPranker 2.0: a gene-centric data mining tool for diseases associated SNP prioritization in GWAS. PMID:23369106
Identifying protein interaction subnetworks by a bagging Markov random field-based method. PMID:23161673
miRNA regulons associated with synaptic function. PMID:23071543
Enhancing the prioritization of disease-causing genes through tissue specific protein interaction networks. PMID:23028288
Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells. PMID:22901239
De novo mutations in ATP1A3 cause alternating hemiplegia of childhood. PMID:22842232
WikiCell: a unified resource platform for human transcriptomics research. PMID:22702248
Germline melanocortin-1-receptor genotype is associated with severity of cutaneous phenotype in congenital melanocytic nevi: a role for MC1R in human fetal development. PMID:22572819
A custom rat and baboon hypertension gene array to compare experimental models. PMID:22228705
Gene network analyses point to the importance of human tissue kallikreins in melanoma progression. PMID:22032772
G-DOC: a systems medicine platform for personalized oncology. PMID:21969811
Identification of ATPAF1 as a novel candidate gene for asthma in children. PMID:21696813
Integrative computational biology for cancer research. PMID:21691773
RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology. PMID:21393386
A scalable approach for discovering conserved active subnetworks across species. PMID:21170309
Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS. PMID:21107268
Genotator: a disease-agnostic tool for genetic annotation of disease. PMID:21034472
Uncovering the human methyltransferasome. PMID:20930037
A maternal low protein diet has pronounced effects on mitochondrial gene expression in offspring liver and skeletal muscle; protective effect of taurine. PMID:20804614
GeneCards Version 3: the human gene integrator. PMID:20689021
GeneBrowser 2: an application to explore and identify common biological traits in a set of genes. PMID:20663121
Deciphering diseases and biological targets for environmental chemicals using toxicogenomics networks. PMID:20502671
GSA-SNP: a general approach for gene set analysis of polymorphisms. PMID:20501604
A Large-scale genetic association study of esophageal adenocarcinoma risk. PMID:20453000
Network Properties for Ranking Predicted miRNA Targets in Breast Cancer. PMID:20224638
Cellular phenotype transformation occurs during thoracic aortic aneurysm development. PMID:20219212
Associating genes and protein complexes with disease via network propagation. PMID:20090828
Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database. PMID:20044737
CanGeneBase (CGB)--a database on cancer related genes. PMID:19759863
Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family. PMID:19747394
Acute molecular response of mouse hindlimb muscles to chronic stimulation. PMID:19625612
FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions. PMID:19374773
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PMID:19300474
Discovery of DNA methylation markers in cervical cancer using relaxation ranking. PMID:19025626
IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels. PMID:18948278
A perspective for biomedical data integration: design of databases for flow cytometry. PMID:18275602
In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer. PMID:17453001
Computational approaches to phenotyping: high-throughput phenomics. PMID:17202287
Gene expression profile differences in left and right liver lobes from mid-gestation fetal baboons: a cautionary tale. PMID:16484296
BEGAIN: a novel imprinted gene that generates paternally expressed transcripts in a tissue- and promoter-specific manner in sheep. PMID:16261422
The path to enlightenment: making sense of genomic and proteomic information. PMID:15629052
DG-CST (Disease Gene Conserved Sequence Tags), a database of human-mouse conserved elements associated to disease genes. PMID:15608249
Differential-display PCR of peripheral blood for biomarker discovery in chronic fatigue syndrome. PMID:15490094
GeneLynx mouse: integrated portal to the mouse genome. PMID:12819149
Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE. PMID:12519968
A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. PMID:12482937
GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support PubMed citations: 158.

158 articles citing: GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support

Exploring the Mechanism of Hawthorn Leaves Against Coronary Heart Disease Using Network Pharmacology and Molecular Docking. PMID:35783840
Mechanistic insight of the potential of geraniol against Alzheimer's disease. PMID:35701806
Mechanisms of Gynostemma pentaphyllum against non-alcoholic fibre liver disease based on network pharmacology and molecular docking. PMID:35665440
Medication Rules in Herbal Medicine for Mild Cognitive Impairment: A Network Pharmacology and Data Mining Study. PMID:35646138
Integrated Network Pharmacology and Clinical Study to Reveal the Effects and Mechanisms of Bushen Huoxue Huatan Decoction on Polycystic Ovary Syndrome. PMID:35600955
Network Pharmacology-Based Approach Combined with Bioinformatic Analytics to Elucidate the Potential of Curcumol against Hepatocellular Carcinoma. PMID:35456457
Cell cycle arrest is an important mechanism of action of compound Kushen injection in the prevention of colorectal cancer. PMID:35288618
Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis. PMID:34949932
Anticancer Potential of Green Synthesized Silver Nanoparticles of the Soft Coral Cladiella pachyclados Supported by Network Pharmacology and In Silico Analyses. PMID:34834261
Single-cell normalization and association testing unifying CRISPR screen and gene co-expression analyses with Normalisr. PMID:34737291
Exploration of the anti-insomnia mechanism of Ganoderma by central-peripheral multi-level interaction network analysis. PMID:34715778
Identifying disease-gene associations using a convolutional neural network-based model by embedding a biological knowledge graph with entity descriptions. PMID:34653225
The gut microbiota instructs the hepatic endothelial cell transcriptome. PMID:34622147
Association of Pericardiac Adipose Tissue With Coronary Artery Disease. PMID:34552562
Network Pharmacology and Molecular Docking-Based Prediction of the Mechanism of Qianghuo Shengshi Decoction against Rheumatoid Arthritis. PMID:34527739
TMEA, a Polyphenol in Sanguisorba officinalis, Promotes Thrombocytopoiesis by Upregulating PI3K/Akt Signaling. PMID:34485295
Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation. PMID:34461807
Systems Pharmacology-Based Precision Therapy and Drug Combination Discovery for Breast Cancer. PMID:34298802
Therapeutic Targets and Mechanism of Xingpi Jieyu Decoction in Depression: A Network Pharmacology Study. PMID:34257681
DGLinker: flexible knowledge-graph prediction of disease-gene associations. PMID:34125897
Systematic elucidation of the mechanism of Jingyin granule in the treatment of Novel Coronavirus (COVID-19) Pneumonia via Network Pharmacology. PMID:33746581
The important herbal pair for the treatment of COVID-19 and its possible mechanisms. PMID:33658066
Computational identification of biomarker genes for lung cancer considering treatment and non-treatment studies. PMID:33272232
Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence. PMID:33154357
Potential Molecular Mechanisms of Plantain in the Treatment of Gout and Hyperuricemia Based on Network Pharmacology. PMID:33149752
Deciphering the Underlying Mechanism of Eucommiae Cortex against Osteoporotic Fracture by Network Pharmacology. PMID:32963568
Application of network pharmacology and molecular docking to elucidate the potential mechanism of Eucommia ulmoides-Radix Achyranthis Bidentatae against osteoarthritis. PMID:32874205
Genetic architecture and genomic selection of female reproduction traits in rainbow trout. PMID:32795250
Mechanisms of Spica Prunellae against thyroid-associated Ophthalmopathy based on network pharmacology and molecular docking. PMID:32689994
Deciphering the underlying mechanism of Xianlinggubao capsule against osteoporosis by network pharmacology. PMID:32620113
Gene expression profiles for low-dose exposure to diethyl phthalate in rodents and humans: a translational study with implications for breast carcinogenesis. PMID:32341500
Investigating the Multi-Target Pharmacological Mechanism of Hedyotis diffusa Willd Acting on Prostate Cancer: A Network Pharmacology Approach. PMID:31600936
A Personalised Dietary Approach-A Way Forward to Manage Nutrient Deficiency, Effects of the Western Diet, and Food Intolerances in Inflammatory Bowel Disease. PMID:31284450
A Network-guided Association Mapping Approach from DNA Methylation to Disease. PMID:30944378
Systematic Survey of the Role of IGF in the Link Between Diabetes and Cancer. PMID:30906876
Effectiveness of imaging genetics analysis to explain degree of depression in Parkinson's disease. PMID:30742647
Comparative transcriptomics identifies genes differentially expressed in the intestine of a new fast-growing strain of common carp with higher unsaturated fatty acid content in muscle. PMID:30395585
Characterization of kinase gene expression and splicing profile in prostate cancer with RNA-Seq data. PMID:30367578
The Xenopus animal cap transcriptome: building a mucociliary epithelium. PMID:30165493
Identification of protein complexes associated with myocardial infarction using a bioinformatics approach. PMID:30132549
BART: bioinformatics array research tool. PMID:30089462
PharmacoDB: an integrative database for mining in vitro anticancer drug screening studies. PMID:30053271
Assessing the functional association of intronic miRNAs with their host genes. PMID:29752351
Navigating the disease landscape: knowledge representations for contextualizing molecular signatures. PMID:29684165
Identification of juvenility-associated genes in the mouse hepatocytes and cardiomyocytes. PMID:29449671
Estimating the mutational load for cardiovascular diseases in Pakistani population. PMID:29420653
G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs? PMID:29298813
Targeted proteomics reveals promising biomarkers of disease activity and organ involvement in antineutrophil cytoplasmic antibody-associated vasculitis. PMID:28962592
Identification of an early transcriptomic signature of insulin resistance and related diseases in lymphomonocytes of healthy subjects. PMID:28777829
Prognostic value of ion channel genes in Chinese patients with gliomas based on mRNA expression profiling. PMID:28752501
Similarity in viral and host promoters couples viral reactivation with host cell migration. PMID:28462923
Gene ORGANizer: linking genes to the organs they affect. PMID:28444223
Comparative network stratification analysis for identifying functional interpretable network biomarkers. PMID:28361683
Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages. PMID:28331091
A scalable algorithm for structure identification of complex gene regulatory network from temporal expression data. PMID:28143596
KBG syndrome involving a single-nucleotide duplication in ANKRD11. PMID:27900361
SCN8A mutation in a child presenting with seizures and developmental delays. PMID:27900360
Gender-Specific Expression of Ubiquitin-Specific Peptidase 9 Modulates Tau Expression and Phosphorylation: Possible Implications for Tauopathies. PMID:27878758
A three ion channel genes-based signature predicts prognosis of primary glioblastoma patients and reveals a chemotherapy sensitive subtype. PMID:27713134
Genome-culture coevolution promotes rapid divergence of killer whale ecotypes. PMID:27243207
Validation of Single Nucleotide Polymorphisms Associated with Carcass Traits in a Commercial Hanwoo Population. PMID:26954199
Core level regulatory network of osteoblast as molecular mechanism for osteoporosis and treatment. PMID:26783964
PPIA rs6850: A > G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease. PMID:26702934
Exome sequencing reveals a high genetic heterogeneity on familial Hirschsprung disease. PMID:26559152
Integrative enrichment analysis: a new computational method to detect dysregulated pathways in heterogeneous samples. PMID:26556243
An Optimization-Driven Analysis Pipeline to Uncover Biomarkers and Signaling Paths: Cervix Cancer. PMID:26388997
Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes. PMID:26311884
SHIELD: an integrative gene expression database for inner ear research. PMID:26209310
Genetic Determinants of Metabolism and Benign Prostate Enlargement: Associations with Prostate Volume. PMID:26158673
Unravelling personalized dysfunctional gene network of complex diseases based on differential network model. PMID:26070628
Identification of CTLA2A, DEFB29, WFDC15B, SERPINA1F and MUP19 as Novel Tissue-Specific Secretory Factors in Mouse. PMID:25946105
Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer. PMID:25910082
Machine learning reveals sex-specific 17β-estradiol-responsive expression patterns in white perch (Morone americana) plasma proteins. PMID:25900664
A survey of imprinted gene expression in mouse trophoblast stem cells. PMID:25711832
More than hemoglobin - the unexpected diversity of globins in vertebrate red blood cells. PMID:25649247
HGV&TB: a comprehensive online resource on human genes and genetic variants associated with tuberculosis. PMID:25502817
Roles of intragenic and intergenic L1s in mouse and human. PMID:25409429
Text mining in cancer gene and pathway prioritization. PMID:25392685
iReport: a generalised Galaxy solution for integrated experimental reporting. PMID:25374662
Expression profiling of mitochondrial voltage-dependent anion channel-1 associated genes predicts recurrence-free survival in human carcinomas. PMID:25333947
Systematic identification of transcriptional and post-transcriptional regulations in human respiratory epithelial cells during influenza A virus infection. PMID:25281301
A meta-analysis of multiple matched copy number and transcriptomics data sets for inferring gene regulatory relationships. PMID:25148247
Clinic-genomic association mining for colorectal cancer using publicly available datasets. PMID:24987669
DNA methylation profiles in primary cutaneous melanomas are associated with clinically significant pathologic features. PMID:24986547
Genes influenced by the non-muscle isoform of Myosin light chain kinase impact human cancer prognosis. PMID:24714365
The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation. PMID:24578356
Ion channel gene expression in lung adenocarcinoma: potential role in prognosis and diagnosis. PMID:24466154
Chromosome positioning from activity-based segregation. PMID:24459132
Candidate genes involved in beneficial or adverse responses to commonly eaten brassica vegetables in a New Zealand Crohn's disease cohort. PMID:24352087
Expression profiling of ion channel genes predicts clinical outcome in breast cancer. PMID:24053408
Gentrepid V2.0: a web server for candidate disease gene prediction. PMID:23947436
Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients. PMID:23538338
Wiki-pi: a web-server of annotated human protein-protein interactions to aid in discovery of protein function. PMID:23209562
NOD2 Polymorphisms and Their Impact on Haematopoietic Stem Cell Transplant Outcome. PMID:23119165
Global probabilistic annotation of metabolic networks enables enzyme discovery. PMID:22960854
Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity. PMID:22829723
Using rule-based machine learning for candidate disease gene prioritization and sample classification of cancer gene expression data. PMID:22808075
Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers. PMID:22676183
Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel. PMID:22437668
Integrative analyses of conserved WNT clusters and their co-operative behaviour in human breast cancer. PMID:22355234
Genetic polymorphisms in fatty acid metabolism genes and colorectal cancer. PMID:22294764
Inferring gene-phenotype associations via global protein complex network propagation. PMID:21799737
Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival. PMID:21619627
Systems analysis of salivary gland development and disease. PMID:20890964
Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme. PMID:20822536
Tumor antigen analysis in neuroblastoma by serological interrogation of bioinformatic data. PMID:20718755
GeneCards Version 3: the human gene integrator. PMID:20689021
[Identification of candidate genes for lung adenocarcinoma using Toppgene]. PMID:20677550
Quantitative gene expression profiles in real time from expressed sequence tag databases. PMID:20635574
Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. PMID:20598109
A Large-scale genetic association study of esophageal adenocarcinoma risk. PMID:20453000
Module network inference from a cancer gene expression data set identifies microRNA regulated modules. PMID:20418949
Mutation@A Glance: an integrative web application for analysing mutations from human genetic diseases. PMID:20360267
HDAPD: a web tool for searching the disease-associated protein structures. PMID:20158919
GIFtS: annotation landscape analysis with GeneCards. PMID:19852797
Coexpression network based on natural variation in human gene expression reveals gene interactions and functions. PMID:19797678
Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? PMID:19710312
Genomic and Proteomic Biomarker Discovery in Neurological Disease. PMID:19578496
Gene Prospector: an evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseases. PMID:19063745
Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample. PMID:18704094
Trans-natural antisense transcripts including noncoding RNAs in 10 species: implications for expression regulation. PMID:18653530
Meta-analysis of nasopharyngeal carcinoma microarray data explores mechanism of EBV-regulated neoplastic transformation. PMID:18605998
Genetic susceptibility to occupational exposures. PMID:18487431
Extraction of semantic biomedical relations from text using conditional random fields. PMID:18433469
Protein databases on the internet. PMID:18265344
A molecular specificity code for the three mammalian KDEL receptors. PMID:18086916
DrugBank: a knowledgebase for drugs, drug actions and drug targets. PMID:18048412
X:Map: annotation and visualization of genome structure for Affymetrix exon array analysis. PMID:17932061
PubMeth: a cancer methylation database combining text-mining and expert annotation. PMID:17932060
IDR knowledge base for primary immunodeficiencies. PMID:17394641
Computational approaches to phenotyping: high-throughput phenomics. PMID:17202287
GeneTools--application for functional annotation and statistical hypothesis testing. PMID:17062145
NovelFam3000--uncharacterized human protein domains conserved across model organisms. PMID:16533400
Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery. PMID:16463010
DrugBank: a comprehensive resource for in silico drug discovery and exploration. PMID:16381955
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. PMID:15701730
Visualizing information across multidimensional post-genomic structured and textual databases. PMID:15598839
Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. PMID:15564486
TXTGate: profiling gene groups with text-based information. PMID:15186494
The CyberCell Database (CCDB): a comprehensive, self-updating, relational database to coordinate and facilitate in silico modeling of Escherichia coli. PMID:14681416
The German cDNA network: cDNAs, functional genomics and proteomics. PMID:14649292
DAVID: Database for Annotation, Visualization, and Integrated Discovery. PMID:12734009
The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003. PMID:12520024
Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE. PMID:12519968
ASAP: the Alternative Splicing Annotation Project. PMID:12519958
Associations between human disease genes and overlapping gene groups and multiple amino acid runs. PMID:12473749
Identification of genes involved in resistance to interferon-alpha in cutaneous T-cell lymphoma. PMID:12414529
An introduction to information retrieval: applications in genomics. PMID:12049181
FIMM, a database of functional molecular immunology: update 2002. PMID:11752300
Genew: the human gene nomenclature database. PMID:11752283
HUGE: a database for human large proteins identified in the Kazusa cDNA sequencing project. PMID:11752282
euGenes: a eukaryote genome information system. PMID:11752277
GeneLynx: a gene-centric portal to the human genome. PMID:11731507
Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5. PMID:11239002
Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. PMID:11230166
Atlas of Genetics and Cytogenetics in Oncology and Haematology, updated. PMID:11125120
Atlas of genetics and cytogenetics in oncology and haematology, an interactive database. PMID:10592271
FIMM, a database of functional molecular immunology. PMID:10592231
GeneCards 2002: towards a complete, object-oriented, human gene compendium PubMed citations: 71.

71 articles citing: GeneCards 2002: towards a complete, object-oriented, human gene compendium

Single-Cell Transcriptome Analysis Reveals Mesenchymal Stem Cells in Cavernous Hemangioma. PMID:35865633
Study on the Mechanism of Astragalus Polysaccharide in Treating Pulmonary Fibrosis Based on "Drug-Target-Pathway" Network. PMID:35370663
The mechanism of triptolide in the treatment of connective tissue disease-related interstitial lung disease based on network pharmacology and molecular docking. PMID:35132912
Kaempferol and Apigenin suppresses the stemness properties of TNBC cells by modulating Sirtuins. PMID:35129762
Prediction of the Mechanisms by Which Quercetin Enhances Cisplatin Action in Cervical Cancer: A Network Pharmacology Study and Experimental Validation. PMID:35070983
Network pharmacology-based strategy to investigate the active ingredients and molecular mechanisms of Scutellaria Barbata D. Don against radiation pneumonitis. PMID:34964782
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis. PMID:34603058
A small molecule compound berberine as an orally active therapeutic candidate against COVID-19 and SARS: A computational and mechanistic study. PMID:33749932
Determining crucial genes associated with COVID-19 based on COPD Findings✶,✶✶. PMID:33260035
Genetic parameters and associated genomic regions for global immunocompetence and other health-related traits in pigs. PMID:33116177
Genome-wide association study for feed efficiency in collective cage-raised rabbits under full and restricted feeding. PMID:32697387
DISNET: a framework for extracting phenotypic disease information from public sources. PMID:32110491
The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology. PMID:31412658
Protein Bioinformatics Databases and Resources. PMID:28150231
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat. PMID:27666082
Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers. PMID:27436900
Cognitive endophenotypes inform genome-wide expression profiling in schizophrenia. PMID:26710095
Decreased MicroRNA-26a expression causes cisplatin resistance in human non-small cell lung cancer. PMID:26492332
Unique ability of pandemic influenza to downregulate the genes involved in neuronal disorders. PMID:26246405
Integrated systems approach identifies risk regulatory pathways and key regulators in coronary artery disease. PMID:26208504
Complex-based analysis of dysregulated cellular processes in cancer. PMID:25521701
Text mining in cancer gene and pathway prioritization. PMID:25392685
Predicting targeted drug combinations based on Pareto optimal patterns of coexpression network connectivity. PMID:24944582
Unraveling human protein interaction networks underlying co-occurrences of diseases and pathological conditions. PMID:24731539
Chromosome positioning from activity-based segregation. PMID:24459132
Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort. PMID:23981286
PGMRA: a web server for (phenotype x genotype) many-to-many relation analysis in GWAS. PMID:23761451
MetaRanker 2.0: a web server for prioritization of genetic variation data. PMID:23703204
The network organization of cancer-associated protein complexes in human tissues. PMID:23567845
microRNA dysregulation in prostate cancer: network analysis reveals preferential regulation of highly connected nodes. PMID:22589088
The transcription factor encyclopedia. PMID:22458515
VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. PMID:22300766
In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer. PMID:21923952
Dominating biological networks. PMID:21887225
High-throughput mapping of the promoters of the mouse olfactory receptor genes reveals a new type of mammalian promoter and provides insight into olfactory receptor gene regulation. PMID:21705439
Cadmium induces transcription independently of intracellular calcium mobilization. PMID:21694771
Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study. PMID:21453500
Current trends and new challenges of databases and web applications for systems driven biological research. PMID:21423387
Differential expression of CHL1 gene during development of major human cancers. PMID:21408220
Glaucoma database. PMID:21383909
ChemProt: a disease chemical biology database. PMID:20935044
GeneCards Version 3: the human gene integrator. PMID:20689021
A Large-scale genetic association study of esophageal adenocarcinoma risk. PMID:20453000
DASMiner: discovering and integrating data from DAS sources. PMID:19919683
GIFtS: annotation landscape analysis with GeneCards. PMID:19852797
DDEC: Dragon database of genes implicated in esophageal cancer. PMID:19580656
The Human Gene Mutation Database: 2008 update. PMID:19348700
A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes. PMID:19104045
Prioritizing genes of potential relevance to diseases affected by sex hormones: an example of myasthenia gravis. PMID:18851734
PharmGKB: an integrated resource of pharmacogenomic data and knowledge. PMID:18819074
Database for exploration of functional context of genes implicated in ovarian cancer. PMID:18790805
Meta-analysis of nasopharyngeal carcinoma microarray data explores mechanism of EBV-regulated neoplastic transformation. PMID:18605998
Quantitative analysis on the characteristics of targets with FDA approved drugs. PMID:18167532
The Edinburgh human metabolic network reconstruction and its functional analysis. PMID:17882155
Global reconstruction of the human metabolic network based on genomic and bibliomic data. PMID:17267599
DiscoverySpace: an interactive data analysis application. PMID:17210078
Computational approaches to phenotyping: high-throughput phenomics. PMID:17202287
The Rat Genome Database, update 2007--easing the path from disease to data and back again. PMID:17151068
Challenges and strategies of the Genetics Home Reference. PMID:16888669
The comparative toxicogenomics database: a cross-species resource for building chemical-gene interaction networks. PMID:16675512
Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration. PMID:16426464
Automating genomic data mining via a sequence-based matrix format and associative rule set. PMID:16026599
A multistep bioinformatic approach detects putative regulatory elements in gene promoters. PMID:15904489
The path to enlightenment: making sense of genomic and proteomic information. PMID:15629052
HAGR: the Human Ageing Genomic Resources. PMID:15608256
TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies. PMID:15608156
Consensus clustering and functional interpretation of gene-expression data. PMID:15535870
Design of Genetics Home Reference: a new NLM consumer health resource. PMID:15298997
FREP: a database of functional repeats in mouse cDNAs. PMID:14681460
IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data. PMID:14681396
Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE. PMID:12519968
http://dx.doi.org/10.1186/s12864-016-2722-2

http://dx.doi.org/10.1093/database/baw030

http://dx.doi.org/10.1002/cpbi.5

http://dx.doi.org/10.1089/omi.2015.0168

http://dx.doi.org/10.1093/database/bav006

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genome
metasource: Fairsharing.org
version: FAIRsharing.org: GeneCards; GeneCards: human genes, protein and diseases; DOI: https://doi.org/10.25504/FAIRsharing.g7jbvn; Last edited: June 22, 2021, 11:59 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

human and other vertebrate genomes
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

human genome databases, maps and viewers
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

human genes and diseases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

general human genetics databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

bioinformatics
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

biological pathway
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

biology
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

cell
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

disease
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

genetics
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

genomics
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

medicine
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

protein
metasource: re3data.org
version: re3data.org: GeneCards; editing status 2019-01-15; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3D643 last accessed: 2022-11-04

human genetics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

molecular interactions, pathways and networks
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

function analysis
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

data integration and warehousing
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

rare diseases
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:57.636780

genome human and other vertebrate genomes human genome, maps and viewers human genes and diseases general human genetics bioinformatics biological pathway cell disease genetics genomics medicine protein human genetics molecular interactions, pathways and networks function analysis data integration and warehousing rare diseases

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Locus Reference Genomic sequences

Human Gene and Protein Database

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