miRandola: extracellular circulating RNAs database
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miRandola: extracellular circulating RNAs database
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
miRandola
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
miRandola: extracellular circulating RNAs database
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
miRandola
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
miRandola: extracellular circulating RNAs database
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
miRandola
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
The miRandola database is the first resource for extracellular circulating RNAs. The first version of the database has been published on Plos One in 2012. It mainly contains information on circulating microRNAs and other non-coding RNAs. It is manually curated and constantly updated by the authors (usually once a year). We have extracted data from PubMed papers and Exocarta (a database that collects data regarding exosomes). We report information on methods of RNA extraction and qualification, diseases, experimental description, expression data and the potential biomarker role. We are updating the database with other RNAs and the future direction is to have a portal for all the non invasive biomarkers such as cell free DNA and circulating tumor cells.
Description
More detailed information about this field from each metasource.
The miRandola database is the first resource for extracellular circulating RNAs. The first version of the database has been published on Plos One in 2012. It mainly contains information on circulating microRNAs and other non-coding RNAs. It is manually curated and constantly updated by the authors (usually once a year). We have extracted data from PubMed papers and Exocarta (a database that collects data regarding exosomes). We report information on methods of RNA extraction and qualification, diseases, experimental description, expression data and the potential biomarker role. We are updating the database with other RNAs and the future direction is to have a portal for all the non invasive biomarkers such as cell free DNA and circulating tumor cells.
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
miRandola (http://mirandola.iit.cnr.it/) is a database of extracellular non-coding RNAs (ncRNAs) that was initially published in 2012, foreseeing the relevance of ncRNAs as non-invasive biomarkers. An increasing amount of experimental evidence shows that ncRNAs are frequently dysregulated in diseases. Further, ncRNAs have been discovered in different extracellular forms, such as exosomes, which circulate in human body fluids. Thus, miRandola 2017 is an effort to update and collect the accumulating information on extracellular ncRNAs that is spread across scientific publications and different databases. Data are manually curated from 314 articles that describe miRNAs, long non-coding RNAs and circular RNAs. Fourteen organisms are now included in the database, and associations of ncRNAs with 25 drugs, 47 sample types and 197 diseases. miRandola also classifies extracellular RNAs based on their extracellular form: Argonaute2 protein, exosome, microvesicle, microparticle, membrane vesicle, high density lipoprotein and circulating. We also implemented a new web interface to improve the user experience.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://mirandola.iit.cnr.it/Webpage
More detailed information about this field from each metasource.
http://mirandola.iit.cnr.it/
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications:
Publications
More detailed information about this field from each metasource.
miRandola: extracellular circulating microRNAs database
PMID: 23094086
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs
PMID: 25077952
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkx854
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
miRandola: extracellular circulating microRNAs database
PMID: 23094086
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs
PMID: 25077952
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkx854
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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miRandola: extracellular circulating microRNAs database
PubMed citations: 79.
79 articles citing: miRandola: extracellular circulating microRNAs database
Exosome microRNAs in Metabolic Syndrome as Tools for the Early Monitoring of Diabetes and Possible Therapeutic Options. PMID:34959658
Age-Related Exosomal and Endogenous Expression Patterns of miR-1, miR-133a, miR-133b, and miR-206 in Skeletal Muscles. PMID:34867435
Designer Exosomes: Smart Nano-Communication Tools for Translational Medicine. PMID:34821724
Rapid changes of miRNAs-20, -30, -410, -515, -134, and -183 and telomerase with psychological activity: A one year study on the relaxation response and epistemological considerations. PMID:34522635
Emerging roles of exosomal miRNAs in diabetes mellitus. PMID:34185424
emiRIT: a text-mining-based resource for microRNA information. PMID:34048547
Exploring Noninvasive Biomarkers with the miRandola Database: A Tool for Translational Medicine. PMID:33835456
Nrp-1 Mediated Plasmatic Ago2 Binding miR-21a-3p Internalization: A Novel Mechanism for miR-21a-3p Accumulation in Renal Tubular Epithelial Cells during Sepsis. PMID:32923478
Circulating microRNA expression profiling in young obese Korean women. PMID:32765820
Exosomal miRNAs in hepatitis B virus related liver disease: a new hope for biomarker. PMID:32346400
The Current State of MicroRNAs as Restenosis Biomarkers. PMID:31998354
The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective. PMID:31709179
A cell-based assay for CD63-containing extracellular vesicles. PMID:31339911
Postprandial Circulating miRNAs in Response to a Dietary Fat Challenge. PMID:31200481
Let-7a inhibits proliferation and promotes apoptosis of human asthmatic airway smooth muscle cells. PMID:30988708
Therapy resistance mediated by exosomes. PMID:30925921
Extracellular Vesicles from Thyroid Carcinoma: The New Frontier of Liquid Biopsy. PMID:30841521
miRBaseConverter: an R/Bioconductor package for converting and retrieving miRNA name, accession, sequence and family information in different versions of miRBase. PMID:30598108
Tissue and exosomal miRNA editing in Non-Small Cell Lung Cancer. PMID:29976955
MicroRNA-410-5p exacerbates high-fat diet-induced cardiac remodeling in mice in an endocrine fashion. PMID:29884823
RNA Biomarkers: Frontier of Precision Medicine for Cancer. PMID:29657281
The decade of exosomal long RNA species: an emerging cancer antagonist. PMID:29558960
Functional Association between Regulatory RNAs and the Annexins. PMID:29462943
miRandola 2017: a curated knowledge base of non-invasive biomarkers. PMID:29036351
Circulating microRNAs and Bioinformatics Tools to Discover Novel Diagnostic Biomarkers of Pediatric Diseases. PMID:28925938
Circulating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort. PMID:28749975
KRAS and BRAF mutations in serum exosomes from patients with colorectal cancer in a Chinese population. PMID:28521461
Progressive changes in non-coding RNA profile in leucocytes with age. PMID:28448962
Computational Analysis of Specific MicroRNA Biomarkers for Noninvasive Early Cancer Detection. PMID:28357401
SpidermiR: An R/Bioconductor Package for Integrative Analysis with miRNA Data. PMID:28134831
The hunt for fatal myocardial infarction biomarkers: predictive circulating microRNAs. PMID:27867969
A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA). PMID:27824314
Specific miRNA Disease Biomarkers in Blood, Serum and Plasma: Challenges and Prospects. PMID:27378479
Web-based tools for microRNAs involved in human cancer. PMID:27284356
Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis. PMID:27259231
KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes. PMID:27117408
Prediction of Immunomodulatory potential of an RNA sequence for designing non-toxic siRNAs and RNA-based vaccine adjuvants. PMID:26861761
MicroRNAs as Biomarkers in Cancer. PMID:26835669
Analysis of Biobanked Serum from a Mycobacterium avium subsp paratuberculosis Bovine Infection Model Confirms the Remarkable Stability of Circulating miRNA Profiles and Defines a Bovine Serum miRNA Repertoire. PMID:26675426
Bioinformatic tools for microRNA dissection. PMID:26578605
Increased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic Retina. PMID:26466127
MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics. PMID:26311337
Extracellular microRNAs as Biomarkers in Human Disease. PMID:26306299
Mini but mighty: microRNAs in the pathobiology of periodontal disease. PMID:26252410
An Exploration of Molecular Correlates Relevant to Radiation Combined Skin-Burn Trauma. PMID:26247844
The Identification of Circulating MiRNA in Bovine Serum and Their Potential as Novel Biomarkers of Early Mycobacterium avium subsp paratuberculosis Infection. PMID:26218736
Small RNAs in metastatic and non-metastatic oral squamous cell carcinoma. PMID:26104160
Kinetic fingerprinting to identify and count single nucleic acids. PMID:26098451
Biological properties of extracellular vesicles and their physiological functions. PMID:25979354
A new method for discovering disease-specific MiRNA-target regulatory networks. PMID:25848944
Upregulation of gingival tissue miR-200b in obese periodontitis subjects. PMID:25630869
A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. PMID:25593199
Comprehensive reconstruction and visualization of non-coding regulatory networks in human. PMID:25540777
The oncogenic and prognostic potential of eight microRNAs identified by a synergetic regulatory network approach in lung cancer. PMID:25539849
The potential of microRNAs in personalized medicine against cancers. PMID:25243170
Binding sites of miR-1273 family on the mRNA of target genes. PMID:25243165
The blood-borne miRNA signature of lung cancer patients is independent of histology but influenced by metastases. PMID:25175044
Let-7a is differentially expressed in bronchial biopsies of patients with severe asthma. PMID:25130484
A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs. PMID:25077952
Novel insights into miRNA in lung and heart inflammatory diseases. PMID:24991086
Point-of-care diagnostic tools to detect circulating microRNAS as biomarkers of disease. PMID:24858962
Extracellular RNA mediates and marks cancer progression. PMID:24783980
Detection and quantification of extracellular microRNAs in murine biofluids. PMID:24629058
MicroRNA signature and function in retinal neovascularization. PMID:24600510
Assessment of RT-qPCR normalization strategies for accurate quantification of extracellular microRNAs in murine serum. PMID:24586621
Analysis of organ-enriched microRNAs in plasma as an approach to development of Universal Screening Test: feasibility study. PMID:24330742
Circulating microRNAs as mirrors of acute coronary syndromes: MiRacle or quagMire? PMID:24188699
Analysis of the microRNA transcriptome and expression of different isomiRs in human peripheral blood mononuclear cells. PMID:24073671
Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies. PMID:24058335
The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies. PMID:23964286
Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover. PMID:23945935
From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review). PMID:23939688
Intercellular communication by exosome-derived microRNAs in cancer. PMID:23839094
Extracellular circulating viral microRNAs: current knowledge and perspectives. PMID:23805153
Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. PMID:23709120
Identification of serum microRNA profiles in colon cancer. PMID:23558896
Extracellular communication via microRNA: lipid particles have a new message. PMID:23505318
Identification of sensitive serum microRNA biomarkers for radiation biodosimetry. PMID:23451251
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. PMID:23384594 -
A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs
PubMed citations: 14.
14 articles citing: A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs
miRNA-based biomarkers, therapies, and resistance in Cancer. PMID:32792861
MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation. PMID:32638565
miRTarBase 2020: updates to the experimentally validated microRNA-target interaction database. PMID:31647101
Impact of Polypharmacy on Candidate Biomarker miRNomes for the Diagnosis of Fibromyalgia and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Striking Back on Treatments. PMID:30889846
Arena-Idb: a platform to build human non-coding RNA interaction networks. PMID:30367585
miRandola 2017: a curated knowledge base of non-invasive biomarkers. PMID:29036351
Circulating microRNAs and Bioinformatics Tools to Discover Novel Diagnostic Biomarkers of Pediatric Diseases. PMID:28925938
Circulating microRNA Profiles as Liquid Biopsies for the Characterization and Diagnosis of Fibromyalgia Syndrome. PMID:27796750
Discovering MicroRNA-Regulatory Modules in Multi-Dimensional Cancer Genomic Data: A Survey of Computational Methods. PMID:27721651
Web-based tools for microRNAs involved in human cancer. PMID:27284356
Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis. PMID:27259231
MicroRNA-143/-145 in Cardiovascular Diseases. PMID:26221598
A new method for discovering disease-specific MiRNA-target regulatory networks. PMID:25848944
Comprehensive reconstruction and visualization of non-coding regulatory networks in human. PMID:25540777 - http://dx.doi.org/10.1093/nar/gkx854
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More detailed information about this field from each metasource.
biomarker
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
cancer
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
cardiovascular disease
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
circulating cell-free rna
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
extracellular exosome
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
long non-coding ribonucleic acid
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
micro rna
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
non-coding rna
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
vesicle
metasource: Fairsharing.org
version: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Tags
More detailed information about this field from each metasource.
biomarker
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
cancer
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
cardiovascular disease
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
circulating cell-free rna
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
extracellular exosome
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
long non-coding ribonucleic acid
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
micro rna
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
non-coding rna
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
vesicle
metasource: Fairsharing.orgversion: FAIRsharing.org: miRandola ; miRandola: extracellular circulating RNAs database; DOI: https://doi.org/10.25504/FAIRsharing.hs4d6r; Last edited: Jan. 8, 2019, 1:22 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
biomarker cancer cardiovascular disease circulating cell-free rna extracellular exosome long non-coding ribonucleic acid micro rna non-coding rna vesicle
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