FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

INTERFEROME
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

interferome
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

Other names: INTERFEROME, interferome

This source may no longer be available. No known URL could be resolved successfully.

This database enables the reliable identification of an individual Interferon Regulated Gene (IRG) or IRG signatures from high-throughput data sets (i.e. microarray, proteomic data etc.). It also assists in identifying regulatory elements, chromosomal location and tissue expression of IRGs in human and mouse. This upgraded version, Interferome v2.0 has quantitative data, more detailed annotation and search capabilities and can be queried for one to a thousand genes, such as from from a microarray experiment.

Webpage:

http://www.interferome.org

Publications:

Publications
More detailed information about this field from each metasource.

Interferome v2.0: an updated database of annotated interferon-regulated genes
PMID: 23203888
metasource: Fairsharing.org
version: FAIRsharing.org: Interferome; Interferome; DOI: https://doi.org/10.25504/FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

INTERFEROME: the database of interferon regulated genes
PMID: 18996892
metasource: Fairsharing.org
version: FAIRsharing.org: Interferome; Interferome; DOI: https://doi.org/10.25504/FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

http://dx.doi.org/10.1093/nar/gks1215
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

Interferome v2.0: an updated database of annotated interferon-regulated genes PubMed citations: 413.

413 articles citing: Interferome v2.0: an updated database of annotated interferon-regulated genes

ADAR1 averts fatal type I interferon induction by ZBP1. PMID:35859176
Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease. PMID:35803230
Insights from two independent transcriptomic studies of the bovine corpus luteum during pregnancy. PMID:35772758
A Microbiota-Dependent Subset of Skin Macrophages Protects Against Cutaneous Bacterial Infection. PMID:35757750
Gene Set Enrichment Analysis Reveals That Fucoidan Induces Type I IFN Pathways in BMDC. PMID:35684042
Systemic Listeria monocytogenes infection in aged mice induces long-term neuroinflammation: the role of miR-155. PMID:35614490
A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition. PMID:35584177
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis. PMID:35525247
Lupus Susceptibility Loci Predispose Mice to Clonal Lymphocytic Responses and Myeloid Expansion. PMID:35477687
The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses. PMID:35475759
Human Cytomegalovirus Infection Elicits Global Changes in Host Transcription by RNA Polymerases I, II, and III. PMID:35458509
Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome. PMID:35439048
IFN-induced cell-autonomous immune mechanisms in the control of intracellular protozoa. PMID:35435512
Precise tumor immune rewiring via synthetic CRISPRa circuits gated by concurrent gain/loss of transcription factors. PMID:35304449
H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway. PMID:35302840
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells. PMID:35301508
Identification of a Tumor Cell Associated Type I IFN Resistance Gene Expression Signature of Human Melanoma, the Components of Which Have a Predictive Potential for Immunotherapy. PMID:35269844
Type-I Interferon Signaling in Fanconi Anemia. PMID:35198459
Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection. PMID:35131898
Alu RNA Structural Features Modulate Immune Cell Activation and A-to-I Editing of Alu RNAs Is Diminished in Human Inflammatory Bowel Disease. PMID:35126398
Single-Cell Monitoring of Activated Innate Immune Signaling by a d2eGFP-Based Reporter Mimicking Time-Restricted Activation of IFNB1 Expression. PMID:35118008
ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression. PMID:35085484
Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. PMID:35021095
Training associated alterations in equine respiratory immunity using a multiomics comparative approach. PMID:35013475
Dual Host and Pathogen RNA-Seq Analysis Unravels Chicken Genes Potentially Involved in Resistance to Highly Pathogenic Avian Influenza Virus Infection. PMID:35003125
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement. PMID:34997115
Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease. PMID:34970970
Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting. PMID:34946847
Co-Regulation of Protein Coding Genes by Transcription Factor and Long Non-Coding RNA in SARS-CoV-2 Infected Cells: An In Silico Analysis. PMID:34940755
Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature. PMID:34917078
Transcriptional Profiling and Machine Learning Unveil a Concordant Biosignature of Type I Interferon-Inducible Host Response Across Nasal Swab and Pulmonary Tissue for COVID-19 Diagnosis. PMID:34880855
Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection. PMID:34871166
Modeling Innate Antiviral Immunity in Physiological Context. PMID:34863779
An Immunomodulatory Transcriptional Signature Associated With Persistent Listeria Infection in Hepatocytes. PMID:34858876
Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection. PMID:34857864
RNA Binding Proteins as Pioneer Determinants of Infection: Protective, Proviral, or Both? PMID:34834978
Epromoters function as a hub to recruit key transcription factors required for the inflammatory response. PMID:34795220
Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer. PMID:34795003
Multi-Omics Analysis of Glioblastoma Cells' Sensitivity to Oncolytic Viruses. PMID:34771433
Mesenchymal stromal cell apoptosis is required for their therapeutic function. PMID:34764248
Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimics. PMID:34762341
Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations. PMID:34741638
Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection. PMID:34675930
A novel phosphoproteomic landscape evoked in response to type I interferon in the brain and in glial cells. PMID:34656141
Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment. PMID:34624222
Impaired function and delayed regeneration of dendritic cells in COVID-19. PMID:34614036
On Deep Landscape Exploration of COVID-19 Patients Cells and Severity Markers. PMID:34603282
Discovery of Genes that Modulate Flavivirus Replication in an Interferon-Dependent Manner. PMID:34599939
Systematic investigation of cytokine signaling activity at the tissue and single-cell levels. PMID:34594031
A prenylated dsRNA sensor protects against severe COVID-19. PMID:34581622
Transcriptional Landscaping Identifies a Beige Adipocyte Depot in the Newborn Mouse. PMID:34572017
Bortezomib induces anti-multiple myeloma immune response mediated by cGAS/STING pathway activation. PMID:34568832
Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy. PMID:34556855
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. PMID:34555357
Making use of transcription factor enrichment to identify functional microRNA-regulons. PMID:34522293
Serum interferon-α2 measured by single-molecule array associates with systemic disease manifestations in Sjögren's syndrome. PMID:34505866
A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis. PMID:34497421
Two Interferon-Stimulated Response Elements Cooperatively Regulate Interferon-Stimulated Gene Expression in West Nile Virus-Infected IFNAR-/- Mouse Embryo Fibroblasts. PMID:34495694
The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PMID:34491982
STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [18F]FLT PET imaging. PMID:34480004
TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity. PMID:34445801
Vitamin C Enhances Antiviral Functions of Lung Epithelial Cells. PMID:34439814
Evolutionary Profile for (Host and Viral) MLKL Indicates Its Activities as a Battlefront for Extensive Counteradaptation. PMID:34436583
Gene Set Enrichment Analysis Reveals Individual Variability in Host Responses in Tuberculosis Patients. PMID:34421903
Proteomic Signature of Host Response to SARS-CoV-2 Infection in the Nasopharynx. PMID:34400346
Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of Omics data from nasopharyngeal samples. PMID:34392148
Hepatitis C virus treatment with direct-acting antivirals induces rapid changes in the hepatic proteome. PMID:34379872
Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses. PMID:34377374
Host ADP-ribosylation and the SARS-CoV-2 macrodomain. PMID:34351418
Differential impacts of TNFα inhibitors on the transcriptome of Th cells. PMID:34301319
DIA-Based Proteome Profiling of Nasopharyngeal Swabs from COVID-19 Patients. PMID:34292740
ETV7 limits antiviral gene expression and control of influenza viruses. PMID:34257104
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration. PMID:34253898
ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions. PMID:34214142
Identification of genes modulated by interferon gamma in breast cancer cells. PMID:34189281
A comprehensive database for integrated analysis of omics data in autoimmune diseases. PMID:34167460
Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics. PMID:34128960
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells. PMID:34127967
The Effect of Interferons on Presentation of Defective Ribosomal Products as HLA Peptides. PMID:34087483
Diabetes and Cardiovascular Complications: The Epidemics Continue. PMID:34081211
ELAVL1 primarily couples mRNA stability with the 3' UTRs of interferon-stimulated genes. PMID:34038724
The relationship between cytokine and neutrophil gene network distinguishes SARS-CoV-2-infected patients by sex and age. PMID:34027897
Use of Protein Pegylation to Prolong the Antiviral Effect of IFN Against FMDV. PMID:34025625
Interferon-induced GTPases orchestrate host cell-autonomous defence against bacterial pathogens. PMID:34003245
STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses. PMID:33990617
Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression. PMID:33986751
Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interface. PMID:33969332
Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. PMID:33969321
Zika Virus Infection of Human Iris Pigment Epithelial Cells. PMID:33968035
An Integrated Genomic, Proteomic, and Immunopeptidomic Approach to Discover Treatment-Induced Neoantigens. PMID:33936100
Functional landscape of SARS-CoV-2 cellular restriction. PMID:33930332
Functional Interfaces, Biological Pathways, and Regulations of Interferon-Related DNA Damage Resistance Signature (IRDS) Genes. PMID:33922087
Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation. PMID:33912186
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity. PMID:33903774
Positive natural selection in primate genes of the type I interferon response. PMID:33902453
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses. PMID:33871355
Mammalian and Avian Host Cell Influenza A Restriction Factors. PMID:33810083
Zika Virus Pathogenesis: A Battle for Immune Evasion. PMID:33810028
Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature. PMID:33793565
SARS-CoV-2 infection and smoking: What is the association? A brief review. PMID:33777332
Analysis of human total antibody repertoires in TIF1γ autoantibody positive dermatomyositis. PMID:33772100
De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation. PMID:33767335
Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer. PMID:33750914
Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol. PMID:33684179
NK/ILC1 cells mediate neuroinflammation and brain pathology following congenital CMV infection. PMID:33630019
Toxoplasma gondii infection and its implications within the central nervous system. PMID:33627834
Type I Interferon Signaling Is a Common Factor Driving Streptococcus pneumoniae and Influenza A Virus Shedding and Transmission. PMID:33593970
Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens. PMID:33554062
Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5×FAD mice. PMID:33540048
SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface. PMID:33532791
Magnitude and timing of the antiviral response determine SARS-CoV-2 replication early in infection. PMID:33532783
A murine model of Lyme disease demonstrates that Borrelia burgdorferi colonizes the dura mater and induces inflammation in the central nervous system. PMID:33524035
Tumor cell intrinsic RON signaling suppresses innate immune responses in breast cancer through inhibition of IRAK4 signaling. PMID:33508385
Serial co-expression analysis of host factors from SARS-CoV viruses highly converges with former high-throughput screenings and proposes key regulators. PMID:33458747
Targeted Stat2 deletion in conventional dendritic cells impairs CTL responses but does not affect antibody production. PMID:33457079
SARS-CoV-2 meta-interactome suggests disease-specific, autoimmune pathophysiologies and therapeutic targets. PMID:33456761
Loss of type I IFN responsiveness impairs natural killer cell antitumor activity in breast cancer. PMID:33449132
Does the Global Outbreak of COVID-19 or Other Viral Diseases Threaten the Stem Cell Reservoir Inside the Body? PMID:33403490
All About the RNA: Interferon-Stimulated Genes That Interfere With Viral RNA Processes. PMID:33362792
Predictive Significance of Serum Interferon-Inducible Protein Score for Response to Treatment in Systemic Sclerosis-Related Interstitial Lung Disease. PMID:33350170
DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections. PMID:33298174
Analysis of ALS-related proteins during herpes simplex virus-2 latent infection. PMID:33287823
Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly. PMID:33284835
To Kill But Not Be Killed: Controlling the Activity of Mammalian Pore-Forming Proteins. PMID:33281828
Dual Effects of Let-7b in the Early Stage of Hepatitis C Virus Infection. PMID:33208444
Microglial responses to peripheral type 1 interferon. PMID:33183319
Deep learning approach for predicting functional Z-DNA regions using omics data. PMID:33154517
Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA Level. PMID:33148793
Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. PMID:33148654
Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells. PMID:33140047
Large-Scale Characterization of Systemic Sclerosis Serum Protein Profile: Comparison to Peripheral Blood Cell Transcriptome and Correlations With Skin/Lung Fibrosis. PMID:33131208
A Multiancestry Sex-Stratified Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus. PMID:33119750
A longitudinal and transancestral analysis of DNA methylation patterns and disease activity in lupus patients. PMID:33108347
Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling. PMID:33104735
Interferon-γ signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells. PMID:33057020
Clinical Aspects of Janus Kinase (JAK) Inhibitors in the Cardiovascular System in Patients with Rheumatoid Arthritis. PMID:33036382
Neurturin regulates the lung-resident macrophage inflammatory response to viral infection. PMID:33020210
Intratumoral administration of the Toll-like receptor 7/8 agonist 3M-052 enhances interferon-driven tumor immunogenicity and suppresses metastatic spread in preclinical triple-negative breast cancer. PMID:33005415
The Molecular Interactions of ZIKV and DENV with the Type-I IFN Response. PMID:32937990
Exploratory neuroimmune profiling identifies CNS-specific alterations in COVID-19 patients with neurological involvement. PMID:32935102
ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain. PMID:32931521
Impact of IL-34, IFN-α and IFN-λ1 on activity of systemic lupus erythematosus in Egyptian patients. PMID:32921829
Current approaches used in treating COVID-19 from a molecular mechanisms and immune response perspective. PMID:32905015
Lipid-specific IgMs induce antiviral responses in the CNS: implications for progressive multifocal leukoencephalopathy in multiple sclerosis. PMID:32792006
Bacterial polyphosphates interfere with the innate host defense to infection. PMID:32788578
Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response. PMID:32715615
Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor. PMID:32690704
Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data. PMID:32682335
Glioma escape signature and clonal development under immune pressure. PMID:32603315
COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. PMID:32591762
Impact of Regulatory T Cells on Type 2 Alveolar Epithelial Cell Transcriptomes during Resolution of Acute Lung Injury and Contributions of IFN-γ. PMID:32543909
Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica. PMID:32503977
Cytomegaloviruses and Macrophages-Friends and Foes From Early on? PMID:32477336
Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract. PMID:32425701
Immune-profiling of ZIKV-infected patients identifies a distinct function of plasmacytoid dendritic cells for immune cross-regulation. PMID:32415086
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. PMID:32413319
Linking Virus Discovery to Immune Responses Visualized during Zebrafish Infections. PMID:32413307
BAHD1 haploinsufficiency results in anxiety-like phenotypes in male mice. PMID:32407325
Integrated urine proteomics and renal single-cell genomics identify an IFN-γ response gradient in lupus nephritis. PMID:32396533
Dissociation of TRIF bias and adjuvanticity. PMID:32389496
Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system. PMID:32383538
Immune Escape Mediated by Exosomal PD-L1 in Cancer. PMID:32383351
Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP. PMID:32380061
Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone. PMID:32314873
Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein. PMID:32295904
Development of IFN-Stimulated Gene Expression from Embryogenesis through Adulthood, with and without Constitutive MDA5 Pathway Activation. PMID:32277054
Egyptian Rousette IFN-ω Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells. PMID:32231668
LncRNAs in HCV Infection and HCV-Related Liver Disease. PMID:32214045
Global Transcriptome Analysis Identifies a Diagnostic Signature for Early Disseminated Lyme Disease and Its Resolution. PMID:32184234
Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus. PMID:32157125
Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response. PMID:32156810
Immune correlates of postexposure vaccine protection against Marburg virus. PMID:32080323
Pathway mapping of leukocyte transcriptome in influenza patients reveals distinct pathogenic mechanisms associated with progression to severe infection. PMID:32066441
In the mix: the potential benefits of adding GM-CSF to CpG-B in the local treatment of patients with early-stage melanoma. PMID:32002303
Protein and DNA methylation-based scores as surrogate markers for interferon system activation in patients with primary Sjögren's syndrome. PMID:31958277
An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype. PMID:31956894
TYK2 in Tumor Immunosurveillance. PMID:31936322
ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. PMID:31924792
Interferon-Independent Innate Responses to Cytomegalovirus. PMID:31921100
Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions. PMID:31873071
Gene Expression Meta-Analysis Reveals Concordance in Gene Activation, Pathway, and Cell-Type Enrichment in Dermatomyositis Target Tissues. PMID:31872188
The alternative cap-binding complex is required for antiviral defense in vivo. PMID:31856218
Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2. PMID:31836668
The transcription factor NFAT5 limits infection-induced type I interferon responses. PMID:31816635
Interferon-Responsive Genes Are Targeted during the Establishment of Human Cytomegalovirus Latency. PMID:31796538
Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress. PMID:31772304
Global virus outbreaks: Interferons as 1st responders. PMID:31771760
Interferon target-gene expression and epigenomic signatures in health and disease. PMID:31745335
ILF3 contributes to the establishment of the antiviral type I interferon program. PMID:31701124
Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis. PMID:31695690
Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses. PMID:31622448
Meta-analysis of blood genome-wide expression profiling studies in pulmonary arterial hypertension. PMID:31617731
Dual function of miR-1248 links interferon induction and calcium signaling defects in Sjögren's syndrome. PMID:31597594
Transcriptome Sequencing of Peripheral Blood Mononuclear Cells from Elite Controller-Long Term Non Progressors. PMID:31582776
Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity. PMID:31575075
Rethinking Lupus Nephritis Classification on a Molecular Level. PMID:31547518
IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis. PMID:31539532
RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs. PMID:31494035
CiiiDER: A tool for predicting and analysing transcription factor binding sites. PMID:31483836
Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus Induces STAT2 Degradation To Inhibit Interferon Signaling. PMID:31462568
Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjögren's Syndrome. PMID:31428085
Dual RNA-seq in Streptococcus pneumoniae Infection Reveals Compartmentalized Neutrophil Responses in Lung and Pleural Space. PMID:31409659
Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon. PMID:31390156
TRIM69 Inhibits Vesicular Stomatitis Indiana Virus. PMID:31375575
Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection. PMID:31356648
Different Biological Activities of Specific Interferon Alpha Subtypes. PMID:31341068
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases. PMID:31253760
NK Response Correlates with HIV Decrease in Pegylated IFN-α2a-Treated Antiretroviral Therapy-Suppressed Subjects. PMID:31253727
Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles. PMID:31200750
Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity. PMID:31167757
Viral Resistance and IFN Signaling in STAT2 Knockout Fish Cells. PMID:31142600
Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways. PMID:31127086
Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties. PMID:31119329
Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages. PMID:31081799
Dynamics of the Type I Interferon Response During Immunosuppressive Therapy in Rheumatoid Arthritis. PMID:31068954
DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis. PMID:31064978
Gene expression analysis delineates the potential roles of multiple interferons in systemic lupus erythematosus. PMID:31044165
Hes1 attenuates type I IFN responses via VEGF-C and WDFY1. PMID:31015298
Longitudinal profiling of human blood transcriptome in healthy and lupus pregnancy. PMID:30962246
Chemokines Modulate Immune Surveillance in Tumorigenesis, Metastasis, and Response to Immunotherapy. PMID:30873179
Interferon-Independent Upregulation of Interferon-Stimulated Genes during Human Cytomegalovirus Infection is Dependent on IRF3 Expression. PMID:30871003
Interleukin 21 collaborates with interferon-γ for the optimal expression of interferon-stimulated genes and enhances protection against enteric microbial infection. PMID:30818341
The miRNA-targeted transcriptome of porcine alveolar macrophages upon infection with Porcine Reproductive and Respiratory Syndrome Virus. PMID:30816147
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses. PMID:30717826
Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation. PMID:30706626
Comprehensive profiling of translation initiation in influenza virus infected cells. PMID:30673779
A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding. PMID:30575728
Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis. PMID:30550790
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. PMID:30545856
Neuroinvasive Listeria monocytogenes Infection Triggers IFN-Activation of Microglia and Upregulates Microglial miR-155. PMID:30538705
Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression. PMID:30538201
Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells. PMID:30521981
HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies. PMID:30463877
Overexpression of Chicken IRF7 Increased Viral Replication and Programmed Cell Death to the Avian Influenza Virus Infection Through TGF-Beta/FoxO Signaling Axis in DF-1. PMID:30356848
Antiviral resistance of stem cells. PMID:30352329
Influenza Virus NS1 Protein-RNA Interactome Reveals Intron Targeting. PMID:30258002
Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with postinfectious, Borrelia burgdorferi-induced Lyme arthritis. PMID:30218476
Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency. PMID:30143481
Long Non-Coding RNA-Mediated Regulation of the Interferon Response: A New Perspective on a Familiar Theme. PMID:30135954
High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms. PMID:30122656
CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans. PMID:30083606
KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control. PMID:30061100
B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells. PMID:29996101
Interferon-stimulated genes: new platforms and computational approaches. PMID:29982912
Genetic and transcriptomic analyses provide new insights on the early antiviral response to VHSV in resistant and susceptible rainbow trout. PMID:29921219
Secretome Screening Reveals Fibroblast Growth Factors as Novel Inhibitors of Viral Replication. PMID:29899088
Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis. PMID:29867920
Slfn2 Regulates Type I Interferon Responses by Modulating the NF-κB Pathway. PMID:29866656
Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine. PMID:29769207
mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation. PMID:29768212
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice. PMID:29746256
Comparative Transcriptomic Response of Primary and Immortalized Macrophages to Murine Norovirus Infection. PMID:29735480
A direct link between MITF, innate immunity, and hair graying. PMID:29723194
Short-Term Pegylated Interferon α2a Treatment Does Not Significantly Reduce the Viral Reservoir of Simian Immunodeficiency Virus-Infected, Antiretroviral Therapy-Treated Rhesus Macaques. PMID:29720521
Up-regulation of microRNA-203 in influenza A virus infection inhibits viral replication by targeting DR1. PMID:29717211
Impact of Interferon-α Receptor-1 Promoter Polymorphisms on the Transcriptome of the Hepatitis B Virus-Associated Hepatocellular Carcinoma. PMID:29713327
Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment. PMID:29672594
Development of a Validated Interferon Score Using NanoString Technology. PMID:29638206
Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus. PMID:29617672
Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response. PMID:29615469
Deep Sequencing-Based Transcriptome Profiling Reveals Avian Interferon-Stimulated Genes and Provides Comprehensive Insight into Newcastle Disease Virus-Induced Host Responses. PMID:29601508
Architectural B-cell organization in skeletal muscle identifies subtypes of dermatomyositis. PMID:29520367
EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer. PMID:29518696
Regulation of the Interferon Response by lncRNAs in HCV Infection. PMID:29503633
Interferon down-regulation of miR-1225-3p as an antiviral mechanism through modulating Grb2-associated binding protein 3 expression. PMID:29496996
Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu. PMID:29490283
A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection. PMID:29447249
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. PMID:29443960
Comparative proteomics as a tool for identifying specific alterations within interferon response pathways in human glioblastoma multiforme cells. PMID:29416731
High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages. PMID:29403501
SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses. PMID:29391557
Interferons: Reprogramming the Metabolic Network against Viral Infection. PMID:29342871
Module Analysis Captures Pancancer Genetically and Epigenetically Deregulated Cancer Driver Genes for Smoking and Antiviral Response. PMID:29331675
Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection. PMID:29324751
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. PMID:29298869
miR-222 isoforms are differentially regulated by type-I interferon. PMID:29263133
Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses. PMID:29253856
Integrative gene network analysis identifies key signatures, intrinsic networks and host factors for influenza virus A infections. PMID:29214055
The IFN Response in Bats Displays Distinctive IFN-Stimulated Gene Expression Kinetics with Atypical RNASEL Induction. PMID:29180486
B Cells Producing Type I IFN Modulate Macrophage Polarization in Tuberculosis. PMID:29161093
Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes. PMID:29119244
Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16. PMID:29118754
An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses. PMID:29117564
Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function. PMID:29106997
Transcriptome Assessment of Erythema Migrans Skin Lesions in Patients With Early Lyme Disease Reveals Predominant Interferon Signaling. PMID:29099929
Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice. PMID:29088242
Interferon regulated gene (IRG) expression-signature in a mouse model of chikungunya virus neurovirulence. PMID:29067635
Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy. PMID:29050360
TC-PTP regulates the IL-7 transcriptional response during murine early T cell development. PMID:29038451
Histone H1 depletion triggers an interferon response in cancer cells via activation of heterochromatic repeats. PMID:28977426
Sweet host revenge: Galectins and GBPs join forces at broken membranes. PMID:28973783
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner. PMID:28959042
Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication. PMID:28953980
Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor. PMID:28947539
A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis. PMID:28935693
C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis. PMID:28922377
SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition. PMID:28916264
Selective HDAC6 inhibition decreases early stage of lupus nephritis by down-regulating both innate and adaptive immune responses. PMID:28876451
Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis. PMID:28827704
Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis. PMID:28827704
Uncovering the immunotherapeutic cycle initiated by p19Arf and interferon-β gene transfer to cancer cells: An inducer of immunogenic cell death. PMID:28811972
Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens. PMID:28811345
Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages. PMID:28768414
Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye. PMID:28721309
Stress-induced changes in miRNA biogenesis and functioning. PMID:28717872
Interferon γ induced compositional changes in human bone marrow derived mesenchymal stem/stromal cells. PMID:28694743
Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma. PMID:28671669
Loss of prion protein induces a primed state of type I interferon-responsive genes. PMID:28651013
Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells. PMID:28622390
IFN-λ1 with Th17 axis cytokines and IFN-α define different subsets in systemic lupus erythematosus (SLE). PMID:28619037
Hepatic expression profiles in retroviral infection: relevance to drug hypersensitivity risk. PMID:28603631
Phantom: investigating heterogeneous gene sets in time-course data. PMID:28595310
Genome-wide characterization of mammalian promoters with distal enhancer functions. PMID:28581502
Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages. PMID:28581443
Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses. PMID:28575086
Restoring PU.1 induces apoptosis and modulates viral transactivation via interferon-stimulated genes in primary effusion lymphoma. PMID:28481873
MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD. PMID:28405612
Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease. PMID:28263993
RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation. PMID:28207896
Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment. PMID:28196594
Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication. PMID:28194021
Understanding Human Autoimmunity and Autoinflammation Through Transcriptomics. PMID:28142321
Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling. PMID:28132836
Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade. PMID:28123870
Promyelocytic Leukemia Protein (PML) Controls Listeria monocytogenes Infection. PMID:28074026
C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. PMID:28069953
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection. PMID:28069942
An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets. PMID:28000722
Identification of context-dependent expression quantitative trait loci in whole blood. PMID:27918533
Tetrabromobisphenol A activates the hepatic interferon pathway in rats. PMID:27914987
Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles. PMID:27913566
Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8+ T cells. PMID:27799536
USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. PMID:27721430
Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. PMID:27712625
Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature. PMID:27663672
N-Myc expression enhances the oncolytic effects of vesicular stomatitis virus in human neuroblastoma cells. PMID:27626059
Chicken interferome: avian interferon-stimulated genes identified by microarray and RNA-seq of primary chick embryo fibroblasts treated with a chicken type I interferon (IFN-α). PMID:27494935
JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response. PMID:27381292
Antibody-Dependent Enhancement of Dengue Virus Infection in Primary Human Macrophages; Balancing Higher Fusion against Antiviral Responses. PMID:27380892
Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis. PMID:27373493
Gene-Expression Profiling Suggests Impaired Signaling via the Interferon Pathway in Cstb-/- Microglia. PMID:27355630
Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function. PMID:27332732
Complex Interplay between HIV-1 Capsid and MX2-Independent Alpha Interferon-Induced Antiviral Factors. PMID:27279606
Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle. PMID:27229711
Cre-dependent DNA recombination activates a STING-dependent innate immune response. PMID:27166376
NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes. PMID:27144453
Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals. PMID:27143386
Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients. PMID:27040498
Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine. PMID:27032388
Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus Virulence. PMID:27009961
Type I and type II interferon responses in two human liver cell lines (Huh-7 and HuH6). PMID:26981398
A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer. PMID:26943587
Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response. PMID:26937035
Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling. PMID:26918359
Physiological evidence for diversification of IFNα- and IFNβ-mediated response programs in different autoimmune diseases. PMID:26882897
Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection. PMID:26861017
Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules. PMID:26768311
Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer. PMID:26695443
Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses. PMID:26682051
Antiviral innate immunity through the lens of systems biology. PMID:26657882
microRNA Function Is Limited to Cytokine Control in the Acute Response to Virus Infection. PMID:26651947
Interferon Kappa Inhibits Human Papillomavirus 31 Transcription by Inducing Sp100 Proteins. PMID:26491169
lncRNA-mediated regulation of the interferon response. PMID:26474526
Fine-tuning of type I IFN-signaling in microglia--implications for homeostasis, CNS autoimmunity and interferonopathies. PMID:26397019
Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205. PMID:26380324
Gene activity in primary T cells infected with HIV89.6: intron retention and induction of genomic repeats. PMID:26377088
Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections. PMID:26360709
Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat. PMID:26223643
MicroRNA as Type I Interferon-Regulated Transcripts and Modulators of the Innate Immune Response. PMID:26217335
The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication. PMID:26196674
Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon Response. PMID:26190101
Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome. PMID:26183421
Six host-range restricted poxviruses from three genera induce distinct gene expression profiles in an in vivo mouse model. PMID:26153454
Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. PMID:26066369
Different STAT Transcription Complexes Drive Early and Delayed Responses to Type I IFNs. PMID:26019270
The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition. PMID:26001115
Suppression of T Cell Activation and Collagen Accumulation by an Anti-IFNAR1 mAb, Anifrolumab, in Adult Patients with Systemic Sclerosis. PMID:25993119
Transcriptome Profiling of the Virus-Induced Innate Immune Response in Pteropus vampyrus and Its Attenuation by Nipah Virus Interferon Antagonist Functions. PMID:25972557
Proteomic analysis reveals down-regulation of surfactant protein B in murine type II pneumocytes infected with influenza A virus. PMID:25965799
Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells. PMID:25896322
Gene expression changes in HLA mismatched mixed lymphocyte cultures reveal genes associated with allorecognition. PMID:25786571
IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes. PMID:25775030
Gene networks specific for innate immunity define post-traumatic stress disorder. PMID:25754082
Quantification of interferon signaling in avian cells. PMID:25720486
Mitochondrial DNA stress primes the antiviral innate immune response. PMID:25642965
NRAV, a long noncoding RNA, modulates antiviral responses through suppression of interferon-stimulated gene transcription. PMID:25525793
Type I interferons link viral infection to enhanced epithelial turnover and repair. PMID:25482432
Type I IFN family members: similarity, differences and interaction. PMID:25466633
An interferon response gene signature is associated with the therapeutic response of hepatitis C patients. PMID:25111807
A comprehensive proteomic view of responses of A549 type II alveolar epithelial cells to human respiratory syncytial virus infection. PMID:25106423
Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. PMID:25100610
Gene expression profiling of the response to interferon beta in Epstein-Barr-transformed and primary B cells of patients with multiple sclerosis. PMID:25025430
Systematic analysis of metastasis-associated genes identifies miR-17-5p as a metastatic suppressor of basal-like breast cancer. PMID:25001613
Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed. PMID:25000983
An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival. PMID:24994117
Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome. PMID:24983321
Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses. PMID:24899188
Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro. PMID:24842522
The bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons. PMID:24809023
Enteropathogenic Escherichia coli inhibits type I interferon- and RNase L-mediated host defense to disrupt intestinal epithelial cell barrier function. PMID:24733098
Lack of group X secreted phospholipase A₂ increases survival following pandemic H1N1 influenza infection. PMID:24725934
STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity. PMID:24710278
Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures. PMID:24644022
Virus-induced transcriptional changes in the brain include the differential expression of genes associated with interferon, apoptosis, interleukin 17 receptor A, and glutamate signaling as well as flavivirus-specific upregulation of tRNA synthetases. PMID:24618253
Late multiple organ surge in interferon-regulated target genes characterizes staphylococcal enterotoxin B lethality. PMID:24551153
Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity. PMID:24478444
The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance. PMID:24466199
Regulation of type I interferon responses. PMID:24362405
Adenovirus E1B 19-kilodalton protein modulates innate immunity through apoptotic mimicry. PMID:24352454
Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection. PMID:24273750
Meta-analysis identifies NF-κB as a therapeutic target in renal cancer. PMID:24116146
Interferon induction and function at the mucosal surface. PMID:23947345
The Interferon-Signature of Sjögren's Syndrome: How Unique Biomarkers Can Identify Underlying Inflammatory and Immunopathological Mechanisms of Specific Diseases. PMID:23847613
INTERFEROME: the database of interferon regulated genes PubMed citations: 120.

120 articles citing: INTERFEROME: the database of interferon regulated genes

Genetic and Clinical Characteristics of Patients in the Middle East With Multisystem Inflammatory Syndrome in Children. PMID:35639375
Rb-E2F-HDAC Repressor Complexes Control Interferon-Induced Repression of Adenovirus To Promote Persistent Infection. PMID:35546119
Interferon-β suppresses inflammatory pain through activating µ-opioid receptor. PMID:34517736
Vitamin C Enhances Antiviral Functions of Lung Epithelial Cells. PMID:34439814
Tunable heat shock protein-mediated NK cell responses are orchestrated by STAT1 in Antigen Presenting Cells. PMID:34373574
Interferon-γ: teammate or opponent in the tumour microenvironment? PMID:34155388
Apatinib combined with PD-L1 blockade synergistically enhances antitumor immune responses and promotes HEV formation in gastric cancer. PMID:33891173
Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol. PMID:33684179
NAD+ depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition. PMID:33597293
MAIT cell activation augments adenovirus vector vaccine immunogenicity. PMID:33510029
Recognition of plausible therapeutic agents to combat COVID-19: An omics data based combined approach. PMID:33346100
The Role of Type I Interferons in the Pathogenesis and Treatment of COVID-19. PMID:33117408
CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev. PMID:33103564
Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain. PMID:33101276
Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis. PMID:33064743
Network Controllability-Based Prioritization of Candidates for SARS-CoV-2 Drug Repositioning. PMID:32993136
Interferon-beta enhances sensitivity to gemcitabine in pancreatic cancer. PMID:32967656
Fishing for newly synthesized proteins with phosphonate-handles. PMID:32591520
ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ. PMID:32339990
A potential association between IL-3 and type I and III interferons in systemic lupus erythematosus. PMID:31890206
Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis. PMID:31664743
Dual function of miR-1248 links interferon induction and calcium signaling defects in Sjögren's syndrome. PMID:31597594
CiiiDER: A tool for predicting and analysing transcription factor binding sites. PMID:31483836
A dual controllability analysis of influenza virus-host protein-protein interaction networks for antiviral drug target discovery. PMID:31159726
How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication. PMID:30886834
ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment. PMID:30770349
Type I Interferon Signaling Is Required for Dacryoadenitis in the Nonobese Diabetic Mouse Model of Sjögren Syndrome. PMID:30347820
Systems vaccinology and big data in the vaccine development chain. PMID:30317555
Neuroimmunomodulation in Major Depressive Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma. PMID:30306457
Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer. PMID:30089113
The Regulation of Inflammation by Innate and Adaptive Lymphocytes. PMID:29992170
Interferon-stimulated genes: new platforms and computational approaches. PMID:29982912
Interferon Signaling Is Frequently Downregulated in Melanoma. PMID:29977240
Influenza A Virus Facilitates Its Infectivity by Activating p53 to Inhibit the Expression of Interferon-Induced Transmembrane Proteins. PMID:29904383
Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2. PMID:29604476
Platform-independent gene expression signature differentiates sessile serrated adenomas/polyps and hyperplastic polyps of the colon. PMID:29284484
In Vitro Evaluation of Glycoengineered RSV-F in the Human Artificial Lymph Node Reactor. PMID:28952549
Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination. PMID:28930286
IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection. PMID:28793350
Restoring PU.1 induces apoptosis and modulates viral transactivation via interferon-stimulated genes in primary effusion lymphoma. PMID:28481873
Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease. PMID:28416283
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation. PMID:28404866
The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond. PMID:28382038
Type I interferon as a biomarker in autoimmunity and viral infection: a leukocyte subset-specific analysis unveils hidden diagnostic options. PMID:28357476
Tissue and time specific expression pattern of interferon regulated genes in the chicken. PMID:28351377
The molecular basis for differential type I interferon signaling. PMID:28289098
Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9. PMID:28213522
Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine. PMID:27905535
A Well-Controlled Experimental System to Study Interactions of Cytotoxic T Lymphocytes with Tumor Cells. PMID:27625650
Meta-Analysis of Differential Connectivity in Gene Co-Expression Networks in Multiple Sclerosis. PMID:27314336
Pharmacogenomics of chronic hepatitis C therapy with genome-wide association studies. PMID:27186094
Antitumour actions of interferons: implications for cancer therapy. PMID:26911188
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid. PMID:26829557
E2F/Rb Family Proteins Mediate Interferon Induced Repression of Adenovirus Immediate Early Transcription to Promote Persistent Viral Infection. PMID:26809031
Innate Immune Signaling Activated by MDR Bacteria in the Airway. PMID:26582515
Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms. PMID:26529416
Oligomerization and GTP-binding Requirements of MxA for Viral Target Recognition and Antiviral Activity against Influenza A Virus. PMID:26507657
Type I interferon dysregulation and neurological disease. PMID:26303851
Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes. PMID:26207988
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. PMID:25894825
Early IFN type I response: Learning from microbial evasion strategies. PMID:25869307
The C-terminal sequence of IFITM1 regulates its anti-HIV-1 activity. PMID:25738301
Disease-promoting effects of type I interferons in viral, bacterial, and coinfections. PMID:25714109
TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA. PMID:25391662
Passive broad-spectrum influenza immunoprophylaxis. PMID:25328697
Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD. PMID:25079358
Type I interferons as regulators of human antigen presenting cell functions. PMID:24866026
Multifaceted activities of type I interferon are revealed by a receptor antagonist. PMID:24866020
Identification of simple sequence repeat biomarkers through cross-species comparison in a tag cloud representation. PMID:24800246
Bridging the species divide: transgenic mice humanized for type-I interferon response. PMID:24416207
Suppression of soluble T cell-associated proteins by an anti-interferon-α monoclonal antibody in adult patients with dermatomyositis or polymyositis. PMID:24357810
Identification of immunomodulatory signatures induced by american ginseng in murine immune cells. PMID:24319490
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine. PMID:24162015
IL7Rα expression and upregulation by IFNβ in dendritic cell subsets is haplotype-dependent. PMID:24147013
Bugs in the system. PMID:23947361
Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease. PMID:23915349
A genome-wide RNAi screen reveals that mRNA decapping restricts bunyaviral replication by limiting the pools of Dcp2-accessible targets for cap-snatching. PMID:23824541
A Comprehensive Profile of ChIP-Seq-Based STAT1 Target Genes Suggests the Complexity of STAT1-Mediated Gene Regulatory Mechanisms. PMID:23645984
Use of transcriptional profiling to delineate the initial response of mice to intravaginal herpes simplex virus type 2 infection. PMID:23638732
Mutant p53 attenuates the anti-tumorigenic activity of fibroblasts-secreted interferon beta. PMID:23630584
Decreased pattern recognition receptor signaling, interferon-signature, and bactericidal/permeability-increasing protein gene expression in cord blood of term low birth weight human newborns. PMID:23626859
Interferons as inducers of apoptosis in malignant cells. PMID:23570382
Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. PMID:23449998
OASL1 inhibits translation of the type I interferon-regulating transcription factor IRF7. PMID:23416614
CD8(+) lymphocytes suppress human immunodeficiency virus 1 replication by secreting type I interferons. PMID:23402527
Host responses to melioidosis and tuberculosis are both dominated by interferon-mediated signaling. PMID:23383015
Activation of invariant NK T cells in periodontitis lesions. PMID:23365081
Monosodium urate activates Src/Pyk2/PI3 kinase and cathepsin dependent unconventional protein secretion from human primary macrophages. PMID:23292187
Evidence for a different susceptibility of primate lentiviruses to type I interferons. PMID:23255800
Interferome v2.0: an updated database of annotated interferon-regulated genes. PMID:23203888
Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses. PMID:23139419
Selection of reference genes for use in quantitative reverse transcription PCR assays when using interferons in U87MG. PMID:23065266
Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation. PMID:23046138
Global secretome characterization of herpes simplex virus 1-infected human primary macrophages. PMID:22973042
Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways. PMID:22938163
The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells. PMID:22912576
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. PMID:22820642
Permissive and restricted virus infection of murine embryonic stem cells. PMID:22815272
Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics. PMID:22713245
RNAimmuno: a database of the nonspecific immunological effects of RNA interference and microRNA reagents. PMID:22411954
Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy. PMID:22291590
Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes. PMID:22147767
IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells. PMID:22096565
Systems-biology approaches to discover anti-viral effectors of the human innate immune response. PMID:21994773
An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones. PMID:21970718
Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state. PMID:21775459
Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibition. PMID:21768647
Cellular transcriptional profiling in human lung epithelial cells infected by different subtypes of influenza A viruses reveals an overall down-regulation of the host p53 pathway. PMID:21651802
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. PMID:21602824
Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γ. PMID:21533215
Excess type I interferon signaling in the mouse seminiferous tubules leads to germ cell loss and sterility. PMID:21515676
HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production. PMID:21411754
The interferon stimulated gene 54 promotes apoptosis. PMID:21190939
Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling. PMID:21074499
Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro. PMID:21029402
The early whole-blood transcriptional signature of dengue virus and features associated with progression to dengue shock syndrome in Vietnamese children and young adults. PMID:20943967
Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs. PMID:20383568
Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages. PMID:20011590
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. PMID:19749758
Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo. PMID:19650917
http://dx.doi.org/10.1093/nar/gks1215

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annotation
metasource: Fairsharing.org
version: FAIRsharing.org: Interferome; Interferome; DOI: https://doi.org/10.25504/FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

computational predictions
metasource: Fairsharing.org
version: FAIRsharing.org: Interferome; Interferome; DOI: https://doi.org/10.25504/FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

gene
metasource: Fairsharing.org
version: FAIRsharing.org: Interferome; Interferome; DOI: https://doi.org/10.25504/FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

interferon
metasource: Fairsharing.org
version: FAIRsharing.org: Interferome; Interferome; DOI: https://doi.org/10.25504/FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

regulation of gene expression
metasource: Fairsharing.org
version: FAIRsharing.org: Interferome; Interferome; DOI: https://doi.org/10.25504/FAIRsharing.pp67qc; Last edited: Jan. 8, 2019, 1:21 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

human genes and diseases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

gene-, system- or disease-specific databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

gene regulation
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

gene expression
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

molecular interactions, pathways and networks
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

transcription factors and regulatory sites
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

computational predictions gene interferon regulation of gene expression human genes and diseases gene-, system- or disease-specific gene regulation gene expression molecular interactions, pathways and networks transcription factors and regulatory sites

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Expression Atlas

PROkariotIC Database Of Gene-Regulation

PAZAR

G2Cdb

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The Arabidopsis Gene Regulatory Information Server

PGDB

MGI Mouse Gene Expression Database

PubAngioGen

SZGR

PCOSKB

KERIS

Gene Expression Barcode

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e-Mouse Atlas of Gene Expression

EpilepsyGene

Mouse Atlas of Gene Expression

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GEneSTATION