Tag: gene-, system- or disease-specific

DisGeNET is a discovery platform containing one of the largest collections available of genes and variants involved in human diseases. DisGeNET integrates data from expert curated repositories, GWAS catalogues, animal models, and the scientific liter ...

The Autism Chromosome Rearrangement Database is a collection of hand curated breakpoints and other genomic features, related to autism, taken from publicly available literature, databases and unpublished data.

This database enables the reliable identification of an individual Interferon Regulated Gene (IRG) or IRG signatures from high-throughput data sets (i.e. microarray, proteomic data etc.). It also assists in identifying regulatory elements, chromosoma ...

GWASdb comprises of collections of traits/diseases associated SNP (TASs) from current GWAS and their comprehensive functional annotations, as well as disease classifications.

A registry of Hereditary Auto-inflammatory Disorder Mutations.

Autism genetics KnowledgeBase, an evidence-based knowledgebase of autism genetics.

The human disease methylation database, DiseaseMeth is a web based resource focused on the aberrant methylomes of human diseases. Until recently, bulks of large-scale data are avaible and are increasingly grown, from which more information can be min ...

Proteins involved in self-digestion of eukaryotic cells

The Selective Targets database (SelTarbase ) is a curated database of public MNR mutation data in microsatellite unstable human tumors. A comprehensive database of all human coding, untranslated, non-coding RNA- and intronic MNRs (MNR_ensembl) is als ...

The Resource of Asian Primary Immunodeficiency Diseases (RAPID) is a repository of molecular alterations in primary immunodeficiency diseases (PID). It hosts information on sequence variations and expression at the mRNA and protein levels of all gene ...

Coronary Artery Disease gene database

Dr.VIS collects and locates human disease-related viral integration sites. So far, about 600 sites covering 5 virus organisms and 11 human diseases are available. Integration sites in Dr.VIS are located against chromesome, cytoband, gene and refseq p ...

The DistiLD database aims to increase the usage of existing genome-wide association studies (GWAS) results by making it easy to query and visualize disease-associated SNPs and genes in their chromosomal context.

Blood Group Antigen Gene Mutation Database

A genetic database for attention deficit hyperactivity disorder. ADHDgene aims to provide research community with a central genetic resource and analysis platform for ADHD, to help unveil the genetic basis of ADHD and to contribute to global mental h ...

The SpliceDisease database provides information linking RNA splicing to human disease, including the change of the nucleotide in the sequence, the location of the mutation on the gene, the reference Pubmed ID and detailed description for the relation ...

Nervous System Disease NcRNAome Atlas

The Type 2 Diabetes Knowledge Portal is an open-access resource for human genetic information on type 2 diabetes (T2D). It is a central repository for data from large genomic studies that identify DNA variants whose presence is linked to altered risk ...

CarpeDB serves as a novel source for epilepsy researchers by featuring scores of "epilepsy genes" and associated publications in one locus. Furthermore, multiple genes implicated in epilepsy are also implicated in other human disorders.

A curated database of mutations and polymorphisms associated with Lafora Progressive Myoclonus Epilepsy. The Lafora progressive myoclonus epilepsy mutation and polymorphism database is a collection of hand curated mutation and polymorphism data for t ...

With the rapid progress of the HLPP (Human Liver Proteome Project), a massive quantity of liver proteome expression profile data has been generated. To manage the valuable resource effectively and present it for researchers, a web-based database of l ...

Genes to Cognition

Public angiogenesis research portal

SchiZophrenia Gene Resource

Prostate and prostatic diseases gene database

Kaleidoscope of gEne Responses to Inflammation among Species

Evolutionary genomics of pregnancy-related tissues and phenotypes

Associations between genes methylated in diseases

Genes, diseases, and pathways associated with PolyCystic Ovary Syndrome

Human haemoglobin variants and thalassemias

X-linked severe combined immunodeficiency mutations

Families of proteins functioning in the eye

Mutation Database for Parkinson's Disease

Genes and mutations related to epilepsy

Genes transcribed in differentiating human erythroid cells

Human ageing-related data

Database for the eukaryotic DNA replication community

Autoimmune lymphoproliferative syndrome database

Clustering of homeobox genes

Mutations in the OCRL1 gene encoding phosphatidylinositol-4,5-bisphosphate 5-phosphatase

KBERG is a database to decipher the functional association of Estrogen Responsive Genes, espcially the transcriptional regulation and functional classification of ERG.

HDBase is a community website for Huntington's Disease (HD) research. Presently, contains protein-protein interaction data centered around the HD protein (huntingtin) and information on therapeutic studies in mouse.

Plasma membrane protein sequences, literature, and expression database

ImmunoBase is a web based resource focused on the genetics and genomics of immunologically related human diseases. Our mission is to provide a curated and integrated set of datasets and tools, across multiple diseases, to support and promote research ...

Estrogen responsive genes database

Ethanol-Related Gene Resource (ERGR) is a comprehensive and useful gene resource to the Ethanol/Alcohol research community. Currently, the ERGR database contains more than 30 large datasets from literature and 21 mouse QTLs from public databases. The ...

NEIBank is a project for ocular genomics. This includes both the generation and analysis of new cDNA libraries for human and animal model eye tissues and the creation of a database and web site for eye-related expression data, known eye disease genes ...

The AlzGene (http://www.alzgene.org) database aims to provide an unbiased, centralized, publicly available and regularly updated collection of genetic association studies performed on Alzheimer's disease (AD) phenotypes. Data is collected following s ...

Synaptic protein database (SynDB, available at http://syndb.cbi.pku.edu.cn), is a manually curated database of the molecular biology of the synapse proteome. It contains a comprehensive collection of proteins (13580 unique proteins spanning 650 spec ...

The imprinted gene and parent-of-origin effect database (http://www.otago.ac.nz/IGC) consists of two sections. One section catalogues the current literature on imprinted genes in humans and animals. The second, and new, section catalogues current rep ...

Perturbations of mammalian organisms including diseases, drug treatments and gene perturbations in mice affect organ systems differently. Some perturbations impair relatively few organ systems while others lead to highly heterogeneous or systemic eff ...

EndoNet is a new database that provides information about the components of endocrine networks and their relations. It focuses on the endocrine cell-to-cell communication and enables the analysis of intercellular regulatory pathways in humans. In the ...

The GOLD.db (Genomics of Lipid-Associated Disorders Database) was developed to address the need for integrating disparate information on the function and properties of genes and their protein products that are particularly relevant to the biology, di ...

A surprising finding in human transcriptome analysis is that protein-coding sequences only account for a small portion of the genome transcripts (1). The majority of the human genome transcripts are noncoding RNAs, in particular, long noncoding RNAs ...

Olfactory receptors (ORs) constitute the largest multi-gene family in multi-cellular organisms. Their evolutionary proliferation has been driven by the need to provide recognition capacity for millions of potential odorants with arbitrary chemical co ...

The Human Intermediate Filament Database (http://www.interfil.org) was initiated by the Human Genetics Unit, University of Dundee in 2001 and was revised by the Centre for Molecular Medicine and the Bioinformatics Institute in Singapore in 2006, from ...