GeneAnnot

The GeneAnnot system revises and improves annotation of Affymetrix probe sets. The many-to-many relationship between probe-sets and genes is elucidated by GeneAnnot's direct sequence comparison of probes to Genbank, RefSeq and Ensembl mRNA sequences. Whenever possible, probe sets are related to GeneCards genes (http://bioinfo.weizmann.ac.il/cards), with sensitivity and specificity scores assigned to each probe-set to gene match. The sensitivity score measures how many probes in a probe-set connect to a particular gene; specificity measures how many other genes match a probe-set, and with how many probes. If no match to GeneCards is found, probe sets are annotated by their relation to GenBank mRNA sequences and UniGene (http://www.ncbi.nlm.nih.gov/UniGene) clusters. GeneAnnot results are integrated with the GeneCards (http://bioinfo.weizmann.ac.il/cards), GeneLoc (http://genecards.weizmann.ac.il/geneloc/) and GeneNote (http://genecards.weizmann.ac.il/genenote/) databases. For the list of GeneAnnot/GeneCards publications, see http://www.genecards.org/publications.html.

Webpage:
http://genecards.weizmann.ac.il/geneannot/

Tags:

human and other vertebrate genomes human genome, maps and viewers human orfs

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