Domain Interaction Graph Guided ExploreR
Names
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Domain Interaction Graph Guided ExploreR
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
DIGGER
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
digger
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
Names
More detailed information about this field from each metasource.
Domain Interaction Graph Guided ExploreR
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
DIGGER
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
digger
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
Names
More detailed information about this field from each metasource.
Domain Interaction Graph Guided ExploreR
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
DIGGER
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
digger
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
DIGGER is an essential resource for studying the mechanistic consequences of alternative splicing such as isoform-specific interaction and consequence of exon skipping. The database integrates information of domain-domain and protein-protein interactions with residue-level interaction evidence from co-resolved structures. DIGGER allows users to seamlessly switch between isoform and exon-centric views of the interactome and to extract sub-networks of relevant isoforms (isoforms specific PPIs).
Description
More detailed information about this field from each metasource.
DIGGER is an essential resource for studying the mechanistic consequences of alternative splicing such as isoform-specific interaction and consequence of exon skipping. The database integrates information of domain-domain and protein-protein interactions with residue-level interaction evidence from co-resolved structures. DIGGER allows users to seamlessly switch between isoform and exon-centric views of the interactome and to extract sub-networks of relevant isoforms (isoforms specific PPIs).
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
Alternative splicing and protein-protein interactions
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Domain Interaction Graph Guided ExploreR (DIGGER) integrates protein-protein interactions and domain-domain interactions into a joint graph and maps interacting residues to exons. DIGGER allows the users to query exons or isoforms individually or as a set to visually explore their interactions.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
Webpage:
https://exbio.wzw.tum.de/digger/Webpage
More detailed information about this field from each metasource.
https://exbio.wzw.tum.de/digger/
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
https://exbio.wzw.tum.de/digger
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
Licence:
Name: GPL-3.0Licence name
More detailed information about this field from each metasource.
Publications:
Publications
More detailed information about this field from each metasource.
DIGGER: exploring the functional role of alternative splicing in protein interactions
PMID: 32976589
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
https://doi.org/10.1093/nar/gkaa768
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
DIGGER: exploring the functional role of alternative splicing in protein interactions
PMID: 32976589
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
https://doi.org/10.1093/nar/gkaa768
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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DIGGER: exploring the functional role of alternative splicing in protein interactions
PubMed citations: 7.
7 articles citing: DIGGER: exploring the functional role of alternative splicing in protein interactions
Exploring the Potential of Symmetric Exon Deletion to Treat Non-Ischemic Dilated Cardiomyopathy by Removing Frameshift Mutations in TTN. PMID:35741855
Comprehensive Analysis of the Expression and Prognostic Value of LMAN2 in HER2+ Breast Cancer. PMID:35707004
Identification and Validation of Novel Immune-Related Alternative Splicing Signatures as a Prognostic Model for Colon Cancer. PMID:35692800
CpG Site-Specific Methylation-Modulated Divergent Expression of PRSS3 Transcript Variants Facilitates Nongenetic Intratumor Heterogeneity in Human Hepatocellular Carcinoma. PMID:35480112
Probing Isoform Switching Events in Various Cancer Types: Lessons From Pan-Cancer Studies. PMID:34888349
Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases. PMID:34857024
Assessing conservation of alternative splicing with evolutionary splicing graphs. PMID:34266979 - https://doi.org/10.1093/nar/gkaa768
Tags:
Tags
More detailed information about this field from each metasource.
alternative splicing
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
binding motif
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
exon
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
gene expression
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
network model
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein interaction
metasource: Fairsharing.org
version: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein interactions
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
rna splicing
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
gene transcripts
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
proteomics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
sequence analysis
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:58.074886
Tags
More detailed information about this field from each metasource.
alternative splicing
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
binding motif
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
exon
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
gene expression
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
network model
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein interaction
metasource: Fairsharing.orgversion: FAIRsharing.org: DIGGER; Domain Interaction Graph Guided ExploreR; DOI: https://doi.org/10.25504/FAIRsharing.QP9j57; Last edited: May 4, 2021, 9:19 a.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein interactions
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
rna splicing
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
gene transcripts
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
proteomics
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
sequence analysis
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:58.074886
alternative splicing binding motif exon gene expression network model protein interaction protein interaction rna splicing gene transcripts proteomics sequence analysis
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