Enhancer RNA Expression in Response to Glucocorticoid Treatment in Murine Macrophages.
PMID:35011590
Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models.
PMID:34826632
Factorbook: an updated catalog of transcription factor motifs and candidate regulatory motif sites.
PMID:34755879
SBSA: an online service for somatic binding sequence annotation.
PMID:34606615
Formation of artificial chromosomes in Caenorhabditis elegans and analyses of their segregation in mitosis, DNA sequence composition and holocentromere organization.
PMID:34417622
Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases.
PMID:34208629
The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.
PMID:33567280
Mutation bias interacts with composition bias to influence adaptive evolution.
PMID:32986712
The Nubeam reference-free approach to analyze metagenomic sequencing reads.
PMID:32883749
Enhancing the interpretability of transcription factor binding site prediction using attention mechanism.
PMID:32770026
Prediction pipeline for discovery of regulatory motifs associated with Brugia malayi molting.
PMID:32574217
DeeperBind: Enhancing Prediction of Sequence Specificities of DNA Binding Proteins.
PMID:32551184
BLAMM: BLAS-based algorithm for finding position weight matrix occurrences in DNA sequences on CPUs and GPUs.
PMID:32164557
Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions.
PMID:31913281
Zebrafish: A Powerful Model for Understanding the Functional Relevance of Noncoding Region Mutations in Human Genetic Diseases.
PMID:31527394
Regulation of Cyclin E by transcription factors of the naïve pluripotency network in mouse embryonic stem cells.
PMID:31462142
A gene regulatory network explains RET-EDNRB epistasis in Hirschsprung disease.
PMID:31313802
Transcriptomic analysis of the oleaginous yeast Lipomyces starkeyi during lipid accumulation on enzymatically treated corn stover hydrolysate.
PMID:31289462
Predicting functional variants in enhancer and promoter elements using RegulomeDB.
PMID:31228310
Meta-analysis of massively parallel reporter assays enables prediction of regulatory function across cell types.
PMID:31131957
Noise-precision tradeoff in predicting combinations of mutations and drugs.
PMID:31116755
From biophysics to 'omics and systems biology.
PMID:30972433
PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data.
PMID:30951143
DNA-protein interaction: identification, prediction and data analysis.
PMID:30915687
Evolutionary Potential of Cis-Regulatory Mutations to Cause Rapid Changes in Transcription Factor Binding.
PMID:30597011
MODSIDE: a motif discovery pipeline and similarity detector.
PMID:30340511
Spt6 Is Required for the Fidelity of Promoter Selection.
PMID:30318445
Independent erosion of conserved transcription factor binding sites points to shared hindlimb, vision and external testes loss in different mammals.
PMID:30137416
The architecture of an empirical genotype-phenotype map.
PMID:29676774
A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human.
PMID:29518216
Characteristics of functional enrichment and gene expression level of human putative transcriptional target genes.
PMID:29363429
Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse.
PMID:29325037
Local sequence features that influence AP-1 cis-regulatory activity.
PMID:29305491
TF2Network: predicting transcription factor regulators and gene regulatory networks in Arabidopsis using publicly available binding site information.
PMID:29272447
Evidence for a hierarchical transcriptional circuit in Drosophila male germline involving testis-specific TAF and two gene-specific transcription factors, Mod and Acj6.
PMID:29235675
Why Phenotype Robustness Promotes Phenotype Evolvability.
PMID:29228219
Scoring Targets of Transcription in Bacteria Rather than Focusing on Individual Binding Sites.
PMID:29213263
MeDReaders: a database for transcription factors that bind to methylated DNA.
PMID:29145608
Identification of breast cancer associated variants that modulate transcription factor binding.
PMID:28957321
Quantifying the Impact of Non-coding Variants on Transcription Factor-DNA Binding.
PMID:28691125
Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk.
PMID:28671685
Transcription Factor Repertoire of Necrotrophic Fungal Phytopathogen Ascochyta rabiei: Predominance of MYB Transcription Factors As Potential Regulators of Secretome.
PMID:28659964
MOTIFSIM 2.1: An Enhanced Software Platform for Detecting Similarity in Multiple DNA Motif Data Sets.
PMID:28632401
WSMD: weakly-supervised motif discovery in transcription factor ChIP-seq data.
PMID:28607381
Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.
PMID:28585545
DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning.
PMID:28395661
Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation.
PMID:28288100
APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL.
PMID:28260788
Predicting gene expression in massively parallel reporter assays: A comparative study.
PMID:28220625
A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development.
PMID:28011632
Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton.
PMID:27902701
An Empirical Prior Improves Accuracy for Bayesian Estimation of Transcription Factor Binding Site Frequencies within Gene Promoters.
PMID:27812284
Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate.
PMID:27710791
Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease.
PMID:27693352
Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis.
PMID:27426982
Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research.
PMID:27297499
Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data.
PMID:27131787
Characterization of piRNAs across postnatal development in mouse brain.
PMID:27112104
Cis-regulatory architecture of a brain signaling center predates the origin of chordates.
PMID:27064252
Gene regulatory mechanisms underpinning prostate cancer susceptibility.
PMID:26950096
Multi-omics analysis reveals regulators of the response to nitrogen limitation in Yarrowia lipolytica.
PMID:26911370
Genomic sequencing of a dyslexia susceptibility haplotype encompassing ROBO1.
PMID:26877820
Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories.
PMID:26845687
Common variation in atrial fibrillation: navigating the path from genetic association to mechanism.
PMID:26733238
Competition between DNA methylation and transcription factors determines binding of NRF1.
PMID:26675734
Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line.
PMID:26635867
An affinity-structure database of helix-turn-helix: DNA complexes with a universal coordinate system.
PMID:26586237
DiffLogo: a comparative visualization of sequence motifs.
PMID:26577052
Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo.
PMID:26502339
Identification of Predictive Cis-Regulatory Elements Using a Discriminative Objective Function and a Dynamic Search Space.
PMID:26465884
Conservation analysis of sequences flanking the testis-determining gene Sry in 17 mammalian species.
PMID:26444262
Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer.
PMID:26341737
motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites.
PMID:26272984
A microfluidic device for epigenomic profiling using 100 cells.
PMID:26214128
SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps.
PMID:26016777
Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility.
PMID:25984238
DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements.
PMID:25972927
Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract.
PMID:25896808
Unraveling the 3D genome: genomics tools for multiscale exploration.
PMID:25887733
A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury.
PMID:25886903
Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.
PMID:25828096
Tupaia small RNAs provide insights into function and evolution of RNAi-based transposon defense in mammals.
PMID:25802409
Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites.
PMID:25763115
A 190 base pair, TGF-β responsive tooth and fin enhancer is required for stickleback Bmp6 expression.
PMID:25732776
Gene co-expression network analysis provides novel insights into myostatin regulation at three different mouse developmental timepoints.
PMID:25695797
Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation.
PMID:25652663
A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA.
PMID:25629660
Functional and phylogenetic characterization of proteins detected in various nematode intestinal compartments.
PMID:25609831
A systematic survey of the Cys2His2 zinc finger DNA-binding landscape.
PMID:25593323
Chromatin accessibility: a window into the genome.
PMID:25473421
Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2.
PMID:25444159
Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes.
PMID:25428367
Structure-based modeling of protein: DNA specificity.
PMID:25414269
Conservation of trans-acting circuitry during mammalian regulatory evolution.
PMID:25409825
Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element.
PMID:25394790
UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions.
PMID:25378322
Transcriptomic portrait of human Mesenchymal Stromal/Stem Cells isolated from bone marrow and placenta.
PMID:25326687
Abundance, arrangement, and function of sequence motifs in the chicken promoters.
PMID:25318583
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.
PMID:25279814
Determination and inference of eukaryotic transcription factor sequence specificity.
PMID:25215497
The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
PMID:25205108
Differential motif enrichment analysis of paired ChIP-seq experiments.
PMID:25179504
Quality versus accuracy: result of a reanalysis of protein-binding microarrays from the DREAM5 challenge by using BayesPI2 including dinucleotide interdependence.
PMID:25158938
Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes.
PMID:25051172
High-throughput functional testing of ENCODE segmentation predictions.
PMID:25035418
Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements.
PMID:24945837
A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana.
PMID:24914054
A molecular basis for classic blond hair color in Europeans.
PMID:24880339
Motif-based analysis of large nucleotide data sets using MEME-ChIP.
PMID:24853928
Global view of enhancer-promoter interactome in human cells.
PMID:24821768
Imogene: identification of motifs and cis-regulatory modules underlying gene co-regulation.
PMID:24682824
KAnalyze: a fast versatile pipelined k-mer toolkit.
PMID:24642064
Dissecting the causal genetic mechanisms of coronary heart disease.
PMID:24623178
Transcriptional enhancers: from properties to genome-wide predictions.
PMID:24614317
Cell-type and transcription factor specific enrichment of transcriptional cofactor motifs in ENCODE ChIP-seq data.
PMID:24564528
A survey of motif finding Web tools for detecting binding site motifs in ChIP-Seq data.
PMID:24555784
Genome-wide tissue-specific gene expression, co-expression and regulation of co-expressed genes in adult nematode Ascaris suum.
PMID:24516681
Automated discovery of tissue-targeting enhancers and transcription factors from binding motif and gene function data.
PMID:24499934
Disruption of long-range gene regulation in human genetic disease: a kaleidoscope of general principles, diverse mechanisms and unique phenotypic consequences.
PMID:24496500
Sho-saiko-to, a traditional herbal medicine, regulates gene expression and biological function by way of microRNAs in primary mouse hepatocytes.
PMID:24410935
Predicting tissue specific transcription factor binding sites.
PMID:24238150
Structure-aided prediction of mammalian transcription factor complexes in conserved non-coding elements.
PMID:24218641
Discover context-specific combinatorial transcription factor interactions by integrating diverse ChIP-Seq data sets.
PMID:24217919
Fine-mapping an association of FSHR with preterm birth in a Finnish population.
PMID:24205076
Genome wide analysis reveals Zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish.
PMID:24204288
Characterization and identification of cis-regulatory elements in Arabidopsis based on single-nucleotide polymorphism information.
PMID:24204023
Discriminative motif analysis of high-throughput dataset.
PMID:24162561
Screening for protein-DNA interactions by automatable DNA-protein interaction ELISA.
PMID:24146751
Systematic identification of transcriptional regulatory modules from protein-protein interaction networks.
PMID:24137002
An improved SELEX-Seq strategy for characterizing DNA-binding specificity of transcription factor: NF-κB as an example.
PMID:24130762
De novo prediction of DNA-binding specificities for Cys2His2 zinc finger proteins.
PMID:24097433
A general approach for discriminative de novo motif discovery from high-throughput data.
PMID:24057214
Nuclear factor one X regulates Bobby sox during development of the mouse forebrain.
PMID:23852417
DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation.
PMID:23825962
kmer-SVM: a web server for identifying predictive regulatory sequence features in genomic data sets.
PMID:23771147
DNA methylation data analysis and its application to cancer research.
PMID:23750645
PiDNA: Predicting protein-DNA interactions with structural models.
PMID:23703214
p53 Integrates host defense and cell fate during bacterial pneumonia.
PMID:23630228
An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes.
PMID:23523368
Endogenous retroviruses function as species-specific enhancer elements in the placenta.
PMID:23396136
An integrated approach to characterize transcription factor and microRNA regulatory networks involved in Schwann cell response to peripheral nerve injury.
PMID:23387820
Identification of DVA interneuron regulatory sequences in Caenorhabditis elegans.
PMID:23383017
PRISM offers a comprehensive genomic approach to transcription factor function prediction.
PMID:23382538
The underlying molecular and network level mechanisms in the evolution of robustness in gene regulatory networks.
PMID:23300434
Distinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions.
PMID:23295670
The twilight zone of cis element alignments.
PMID:23268451
Pitx1 broadly associates with limb enhancers and is enriched on hindlimb cis-regulatory elements.
PMID:23201014
A multi-parametric flow cytometric assay to analyze DNA-protein interactions.
PMID:23143268
ChIP-seq and beyond: new and improved methodologies to detect and characterize protein-DNA interactions.
PMID:23090257
Three enhancements to the inference of statistical protein-DNA potentials.
PMID:23042633
Assessment of algorithms for inferring positional weight matrix motifs of transcription factor binding sites using protein binding microarray data.
PMID:23029415
Discovery and characterization of human exonic transcriptional regulatory elements.
PMID:23029400
Unbiased discovery of interactions at a control locus driving expression of the cancer-specific therapeutic and diagnostic target, mesothelin.
PMID:23025254
Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions.
PMID:23019221
Circuitry and dynamics of human transcription factor regulatory networks.
PMID:22959076
Annotation of functional variation in personal genomes using RegulomeDB.
PMID:22955989
Predicting cell-type-specific gene expression from regions of open chromatin.
PMID:22955983
Systematic localization of common disease-associated variation in regulatory DNA.
PMID:22955828
An expansive human regulatory lexicon encoded in transcription factor footprints.
PMID:22955618
Increasing coverage of transcription factor position weight matrices through domain-level homology.
PMID:22952610
Deciphering the transcriptional regulation of microRNA genes in humans with ACTLocater.
PMID:22941648
SNP microarray analyses reveal copy number alterations and progressive genome reorganization during tumor development in SVT/t driven mice breast cancer.
PMID:22935085
Regulatory elements of Caenorhabditis elegans ribosomal protein genes.
PMID:22928635
Human developmental enhancers conserved between deuterostomes and protostomes.
PMID:22876195
An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud.
PMID:22701669
3DTF: a web server for predicting transcription factor PWMs using 3D structure-based energy calculations.
PMID:22693215
Recognition models to predict DNA-binding specificities of homeodomain proteins.
PMID:22689783
Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes.
PMID:22684502
Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding.
PMID:22534400
Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.
PMID:22510988
Cis-regulatory logic driving glial cells missing: self-sustaining circuitry in later embryogenesis.
PMID:22509525
A novel 13 base pair insertion in the sonic hedgehog ZRS limb enhancer (ZRS/LMBR1) causes preaxial polydactyly with triphalangeal thumb.
PMID:22495965
Meta-profiles of gene expression during aging: limited similarities between mouse and human and an unexpectedly decreased inflammatory signature.
PMID:22413003
An SNP selection strategy identified IL-22 associating with susceptibility to tuberculosis in Chinese.
PMID:22355539
Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function.
PMID:22328084
TranscriptomeBrowser 3.0: introducing a new compendium of molecular interactions and a new visualization tool for the study of gene regulatory networks.
PMID:22292669
Distal chromatin structure influences local nucleosome positions and gene expression.
PMID:22241769
MUSI: an integrated system for identifying multiple specificity from very large peptide or nucleic acid data sets.
PMID:22210894
GWASdb: a database for human genetic variants identified by genome-wide association studies.
PMID:22139925
YeTFaSCo: a database of evaluated yeast transcription factor sequence specificities.
PMID:22102575
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.
PMID:22080862
Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.
PMID:22037702
Discriminative prediction of mammalian enhancers from DNA sequence.
PMID:21875935
coMOTIF: a mixture framework for identifying transcription factor and a coregulator motif in ChIP-seq data.
PMID:21775309
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity.
PMID:21750106
An integrated ChIP-seq analysis platform with customizable workflows.
PMID:21736739
Enhancers in embryonic stem cells are enriched for transposable elements and genetic variations associated with cancers.
PMID:21685454
Quantitative analysis demonstrates most transcription factors require only simple models of specificity.
PMID:21654662
High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells.
PMID:21625455
Inferring transcription factor complexes from ChIP-seq data.
PMID:21602262
ChIP-Array: combinatory analysis of ChIP-seq/chip and microarray gene expression data to discover direct/indirect targets of a transcription factor.
PMID:21586587
Improved similarity scores for comparing motifs.
PMID:21543443
What does biologically meaningful mean? A perspective on gene regulatory network validation.
PMID:21489330
Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart.
PMID:21415370
An integrated pipeline for the genome-wide analysis of transcription factor binding sites from ChIP-Seq.
PMID:21358819
Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas.
PMID:21352540
Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants.
PMID:21335608
Systematic characterization of protein-DNA interactions.
PMID:21207099
High-throughput mapping of protein occupancy identifies functional elements without the restriction of a candidate factor approach.
PMID:21169336
Predicting DNA-binding specificities of eukaryotic transcription factors.
PMID:21152420
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells.
PMID:21106903
FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system.
PMID:21097781
Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite.
PMID:21060817
Identifying functional relationships within sets of co-expressed genes by combining upstream regulatory motif analysis and gene expression information.
PMID:21047389
UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DNA interactions.
PMID:21037262
Determining the specificity of protein-DNA interactions.
PMID:20877328
High resolution models of transcription factor-DNA affinities improve in vitro and in vivo binding predictions.
PMID:20838582
Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example.
PMID:20685816
Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in Drosophila uncovers a regulatory basis for sensory specification.
PMID:20668662
Metamotifs--a generative model for building families of nucleotide position weight matrices.
PMID:20579334
A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells.
PMID:20508144
A cis-regulatory signature for chordate anterior neuroectodermal genes.
PMID:20419150
Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity.
PMID:20413611
MochiView: versatile software for genome browsing and DNA motif analysis.
PMID:20409324
Functional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances.
PMID:20126523
iMotifs: an integrated sequence motif visualization and analysis environment.
PMID:20106815
Variable structure motifs for transcription factor binding sites.
PMID:20074339
JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles.
PMID:19906716
hPDI: a database of experimental human protein-DNA interactions.
PMID:19900953
Finding distal regulatory elements in the human genome.
PMID:19854636
Quadruple 9-mer-based protein binding microarray with DsRed fusion protein.
PMID:19761621
A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors.
PMID:19632181
Identifying regulatory elements in eukaryotic genomes.
PMID:19498043
Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors.
PMID:19265799
Transcriptional regulation and stabilization of left-right neuronal identity in C. elegans.
PMID:19204119
High-resolution DNA-binding specificity analysis of yeast transcription factors.
PMID:19158363