Transcription Factor Class

Other names: TFClass

TFClass is a resource that classifies eukaryotic transcription factors (TFs) according to their DNA-binding domains. Combining information from different resources, manually checking the retrieved mammalian TF sequences and applying extensive phylogenetic analyses, >39,000 TFs from up to 41 mammalian species were assigned to the Superclasses, Classes, Families and Subfamilies of TFClass. TFClass provides corresponding sequence collections in FASTA format; sequence logos and phylogenetic trees at different classification levels; predicted TF binding sites for human, mouse, dog and cow genomes; and links to several external databases.




binding binding site gene expression transcription transcription factor binding site prediction nucleic acid sequence transcription

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