The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function.
PMID:35179490
Quantitative-enhancer-FACS-seq (QeFS) reveals epistatic interactions among motifs within transcriptional enhancers in developing Drosophila tissue.
PMID:34930411
Two promoters integrate multiple enhancer inputs to drive wild-type knirps expression in the Drosophila melanogaster embryo.
PMID:34849867
A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells.
PMID:34711176
Memes: A motif analysis environment in R using tools from the MEME Suite.
PMID:34570758
Tramtrack acts during late pupal development to direct ant caste identity.
PMID:34550980
A combinatorial cis-regulatory logic restricts color-sensing Rhodopsins to specific photoreceptor subsets in Drosophila.
PMID:34161320
MOCCA: a flexible suite for modelling DNA sequence motif occurrence combinatorics.
PMID:33962556
Drosophila Fezf functions as a transcriptional repressor to direct layer-specific synaptic connectivity in the fly visual system.
PMID:33766917
Fruitless decommissions regulatory elements to implement cell-type-specific neuronal masculinization.
PMID:33600447
Individual differences in honey bee behavior enabled by plasticity in brain gene regulatory networks.
PMID:33350385
Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer.
PMID:33268361
High-resolution analysis of differential gene expression during skeletal muscle atrophy and programmed cell death.
PMID:32926651
Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in Drosophila.
PMID:32490812
Developmental plasticity shapes social traits and selection in a facultatively eusocial bee.
PMID:32471944
Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study.
PMID:32393327
Identification of a master transcription factor and a regulatory mechanism for desiccation tolerance in the anhydrobiotic cell line Pv11.
PMID:32191739
Expression of E93 provides an instructive cue to control dynamic enhancer activity and chromatin accessibility during development.
PMID:32094114
Global shape of Toll activation is determined by wntD enhancer properties.
PMID:31900360
Sharing DNA-binding information across structurally similar proteins enables accurate specificity determination.
PMID:31777934
Transcriptional Silencers in Drosophila Serve a Dual Role as Transcriptional Enhancers in Alternate Cellular Contexts.
PMID:31704182
Serpent/dGATAb regulates Laminin B1 and Laminin B2 expression during Drosophila embryogenesis.
PMID:31685844
The CAF-1 complex couples Hippo pathway target gene expression and DNA replication.
PMID:31553691
Changes in chromatin accessibility ensure robust cell cycle exit in terminally differentiated cells.
PMID:31479438
Multilevel regulation of the glass locus during Drosophila eye development.
PMID:31299050
A Comprehensive Drosophila melanogaster Transcription Factor Interactome.
PMID:30995488
Enabling cell-type-specific behavioral epigenetics in Drosophila: a modified high-yield INTACT method reveals the impact of social environment on the epigenetic landscape in dopaminergic neurons.
PMID:30967153
Inference of Transcription Factor Regulation Patterns Using Gene Expression Covariation in Natural Populations of Drosophila melanogaster.
PMID:30739944
Draft Genome Assembly and Population Genetics of an Agricultural Pollinator, the Solitary Alkali Bee (Halictidae: Nomia melanderi).
PMID:30642875
Aristaless Controls Butterfly Wing Color Variation Used in Mimicry and Mate Choice.
PMID:30415702
Correlated Evolution of Two Copulatory Organs via a Single cis-Regulatory Nucleotide Change.
PMID:30344115
An information theoretic treatment of sequence-to-expression modeling.
PMID:30256780
Hunchback is counter-repressed to regulate even-skipped stripe 2 expression in Drosophila embryos.
PMID:30192762
cis-regulatory architecture of a short-range EGFR organizing center in the Drosophila melanogaster leg.
PMID:30142157
Lateral inhibition: Two modes of non-autonomous negative autoregulation by neuralized.
PMID:30028887
Analysis of Genetic Variation Indicates DNA Shape Involvement in Purifying Selection.
PMID:29850830
Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for enhancer specificity.
PMID:29617378
Cooperative recruitment of Yan via a high-affinity ETS supersite organizes repression to confer specificity and robustness to cardiac cell fate specification.
PMID:29535190
Robust ΦC31-Mediated Genome Engineering in Drosophila melanogaster Using Minimal attP/attB Phage Sites.
PMID:29523637
Cooption of heat shock regulatory system for anhydrobiosis in the sleeping chironomid Polypedilum vanderplanki.
PMID:29463761
Natural variation in stochastic photoreceptor specification and color preference in Drosophila.
PMID:29251595
Evidence for a hierarchical transcriptional circuit in Drosophila male germline involving testis-specific TAF and two gene-specific transcription factors, Mod and Acj6.
PMID:29235675
Synthetic enhancer design by in silico compensatory evolution reveals flexibility and constraint in cis-regulation.
PMID:29187214
CrusTF: a comprehensive resource of transcriptomes for evolutionary and functional studies of crustacean transcription factors.
PMID:29178828
A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance.
PMID:28916541
Nuclear receptors connect progenitor transcription factors to cell cycle control.
PMID:28687780
Evolution and multiple roles of the Pancrustacea specific transcription factor zelda in insects.
PMID:28671979
RSAT matrix-clustering: dynamic exploration and redundancy reduction of transcription factor binding motif collections.
PMID:28591841
An Enhancer's Length and Composition Are Shaped by Its Regulatory Task.
PMID:28588608
Hormone-dependent control of developmental timing through regulation of chromatin accessibility.
PMID:28536147
Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascade.
PMID:28295365
Regulatory logic driving stable levels of defective proventriculus expression during terminal photoreceptor specification in flies.
PMID:28126841
Stable Binding of the Conserved Transcription Factor Grainy Head to its Target Genes Throughout Drosophila melanogaster Development.
PMID:28007888
Chromatin profiling of Drosophila CNS subpopulations identifies active transcriptional enhancers.
PMID:27802137
The transcription factor Ets21C drives tumor growth by cooperating with AP-1.
PMID:27713480
Genome-wide identification of Drosophila dorso-ventral enhancers by differential histone acetylation analysis.
PMID:27678375
Transcriptional activity of the short gastrulation primary enhancer in the ventral midline requires its early activity in the presumptive neurogenic ectoderm.
PMID:27616358
CLIMP: Clustering Motifs via Maximal Cliques with Parallel Computing Design.
PMID:27487245
Nucleotide Interdependency in Transcription Factor Binding Sites in the Drosophila Genome.
PMID:27330274
Spatial distribution of predicted transcription factor binding sites in Drosophila ChIP peaks.
PMID:27264535
Intestinal stem cell response to injury: lessons from Drosophila.
PMID:27137186
Two temporal functions of Glass: Ommatidium patterning and photoreceptor differentiation.
PMID:27105580
Integration of Orthogonal Signaling by the Notch and Dpp Pathways in Drosophila.
PMID:26975664
Widespread colocalization of the Drosophila histone acetyltransferase homolog MYST5 with DREF and insulator proteins at active genes.
PMID:26894919
Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs.
PMID:26840050
Single-base pair differences in a shared motif determine differential Rhodopsin expression.
PMID:26785491
Determination of specificity influencing residues for key transcription factor families.
PMID:26753103
Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing.
PMID:26738816
Gene Regulatory Mechanisms Underlying the Spatial and Temporal Regulation of Target-Dependent Gene Expression in Drosophila Neurons.
PMID:26713626
Evidence for a common evolutionary rate in metazoan transcriptional networks.
PMID:26682651
Predicting the impact of promoter variability on regulatory outputs.
PMID:26675057
Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes.
PMID:26301956
Reliable scaling of position weight matrices for binding strength comparisons between transcription factors.
PMID:26289072
Absence of canonical marks of active chromatin in developmentally regulated genes.
PMID:26280901
motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites.
PMID:26272984
miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression.
PMID:26124181
Regulation of transcription factors on sexual dimorphism of fig wasps.
PMID:26031454
Social evolution. Genomic signatures of evolutionary transitions from solitary to group living.
PMID:25977371
Deconvolving the recognition of DNA shape from sequence.
PMID:25843630
Integrating motif, DNA accessibility and gene expression data to build regulatory maps in an organism.
PMID:25791631
Conservation of transcription factor binding specificities across 600 million years of bilateria evolution.
PMID:25779349
ChIP-nexus enables improved detection of in vivo transcription factor binding footprints.
PMID:25751057
Pervasive variation of transcription factor orthologs contributes to regulatory network evolution.
PMID:25748510
Identifying transcriptional cis-regulatory modules in animal genomes.
PMID:25704908
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED.
PMID:25634895
A systematic survey of the Cys2His2 zinc finger DNA-binding landscape.
PMID:25593323
De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets.
PMID:25442502
Determination and inference of eukaryotic transcription factor sequence specificity.
PMID:25215497
Evidence for deep regulatory similarities in early developmental programs across highly diverged insects.
PMID:25173756
Capicua is involved in Dorsal-mediated repression of zerknüllt expression in Drosophila embryo.
PMID:25059278
iRegulon: from a gene list to a gene regulatory network using large motif and track collections.
PMID:25058159
Motif enrichment tool.
PMID:24860165
Enhancer diversity and the control of a simple pattern of Drosophila CNS midline cell expression.
PMID:24854999
DMINDA: an integrated web server for DNA motif identification and analyses.
PMID:24753419
High-resolution mapping defines the cooperative architecture of Polycomb response elements.
PMID:24668908
Spatial expression of transcription factors in Drosophila embryonic organ development.
PMID:24359758
OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites.
PMID:24271386
TFBSshape: a motif database for DNA shape features of transcription factor binding sites.
PMID:24214955
De novo prediction of DNA-binding specificities for Cys2His2 zinc finger proteins.
PMID:24097433
Flanking sequence context-dependent transcription factor binding in early Drosophila development.
PMID:24093548
Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization.
PMID:23972280
Computational identification of diverse mechanisms underlying transcription factor-DNA occupancy.
PMID:23935523
The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state.
PMID:23874226
Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos.
PMID:23852450
Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development.
PMID:23847101
Twine: display and analysis of cis-regulatory modules.
PMID:23658420
Transcriptional and epigenetic signatures of zygotic genome activation during early Drosophila embryogenesis.
PMID:23560912
Global analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants.
PMID:23471540
CBS: an open platform that integrates predictive methods and epigenetics information to characterize conserved regulatory features in multiple Drosophila genomes.
PMID:23228284
Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions.
PMID:23070853
A complete workflow for the analysis of full-size ChIP-seq (and similar) data sets using peak-motifs.
PMID:22836136
i-cisTarget: an integrative genomics method for the prediction of regulatory features and cis-regulatory modules.
PMID:22718975
Recognition models to predict DNA-binding specificities of homeodomain proteins.
PMID:22689783
Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system.
PMID:22688816
Conserved Motifs and Prediction of Regulatory Modules in Caenorhabditis elegans.
PMID:22540038
Exploring the DNA-recognition potential of homeodomains.
PMID:22539651
Response to the BMP gradient requires highly combinatorial inputs from multiple patterning systems in the Drosophila embryo.
PMID:22513375
DNA-protein interactions: methods for detection and analysis.
PMID:22399265
The TAGteam motif facilitates binding of 21 sequence-specific transcription factors in the Drosophila embryo.
PMID:22247430
Improved accuracy of supervised CRM discovery with interpolated Markov models and cross-species comparison.
PMID:21821659
Genome Surveyor 2.0: cis-regulatory analysis in Drosophila.
PMID:21593125
A modified bacterial one-hybrid system yields improved quantitative models of transcription factor specificity.
PMID:21507886