Pocket Similarity Search using Multiple-Sketches

Other names: PoSSuM, possum

POcket Similarity Search Using Multiple-Sketches (PoSSuM) includes all the discovered protein-small molecule binding site pairs with annotations of various types (e.g., UniProt, CATH, SCOP, SCOPe, EC number and Gene ontology). PoSSuM enables rapid exploration of similar binding sites among structures with different global folds as well as similar folds. Moreover, PoSSuM is useful for predicting the binding ligand for unbound structures.




ligand binding domain binding protein binding site prediction protein interaction small molecule binding structure protein structure protein binding sites transcription factors and regulatory sites nucleic acid sites, features and motifs dna binding sites medicinal chemistry

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