Combining hypothesis- and data-driven neuroscience modeling in FAIR workflows.
PMID:35792600
Boolean modelling as a logic-based dynamic approach in systems medicine.
PMID:35782730
Fluxomics - New Metabolomics Approaches to Monitor Metabolic Pathways.
PMID:35387341
Kinetic and Stoichiometric Modeling-Based Analysis of Docosahexaenoic Acid (DHA) Production Potential by Crypthecodinium cohnii from Glycerol, Glucose and Ethanol.
PMID:35200644
Deep learning allows genome-scale prediction of Michaelis constants from structural features.
PMID:34665809
Music of metagenomics-a review of its applications, analysis pipeline, and associated tools.
PMID:34657989
A protocol for dynamic model calibration.
PMID:34619769
PncsHub: a platform for annotating and analyzing non-classically secreted proteins in Gram-positive bacteria.
PMID:34551435
The effects of model complexity and size on metabolic flux distribution and control: case study in Escherichia coli.
PMID:33743594
Proteome Regulation Patterns Determine Escherichia coli Wild-Type and Mutant Phenotypes.
PMID:33688016
The Metano Modeling Toolbox MMTB: An Intuitive, Web-Based Toolbox Introduced by Two Use Cases.
PMID:33671140
KiMoSys 2.0: an upgraded database for submitting, storing and accessing experimental data for kinetic modeling.
PMID:33247931
BRENDA, the ELIXIR core data resource in 2021: new developments and updates.
PMID:33211880
Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast.
PMID:33043390
Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology.
PMID:32850764
Common biochemical properties of metabolic genes recurrently dysregulated in tumors.
PMID:32411371
Gene-Wise Burden of Coding Variants Correlates to Noncoding Pharmacogenetic Risk Variants.
PMID:32349395
The ETFL formulation allows multi-omics integration in thermodynamics-compliant metabolism and expression models.
PMID:31937763
Automatic construction of metabolic models with enzyme constraints.
PMID:31937255
Data Management in Computational Systems Biology: Exploring Standards, Tools, Databases, and Packaging Best Practices.
PMID:31602618
ModelBricks-modules for reproducible modeling improving model annotation and provenance.
PMID:31602314
Uncertainty reduction in biochemical kinetic models: Enforcing desired model properties.
PMID:31430276
Kinetic modeling of Stickland reactions-coupled methanogenesis for a methanogenic culture.
PMID:31183623
Reproducible pharmacokinetics.
PMID:31004315
Consistency, Inconsistency, and Ambiguity of Metabolite Names in Biochemical Databases Used for Genome-Scale Metabolic Modelling.
PMID:30736318
Integration of enzymatic data in Bacillus subtilis genome-scale metabolic model improves phenotype predictions and enables in silico design of poly-γ-glutamic acid production strains.
PMID:30626384
Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models.
PMID:30531987
Harmonizing semantic annotations for computational models in biology.
PMID:30462164
BRENDA in 2019: a European ELIXIR core data resource.
PMID:30395242
A Review of Dynamic Modeling Approaches and Their Application in Computational Strain Optimization for Metabolic Engineering.
PMID:30108559
In Silico Prediction of Large-Scale Microbial Production Performance: Constraints for Getting Proper Data-Driven Models.
PMID:30105090
DMPy: a Python package for automated mathematical model construction of large-scale metabolic systems.
PMID:29914475
A review of computational tools for design and reconstruction of metabolic pathways.
PMID:29552648
From correlation to causation: analysis of metabolomics data using systems biology approaches.
PMID:29503602
STRENDA DB: enabling the validation and sharing of enzyme kinetics data.
PMID:29498804
Emerging whole-cell modeling principles and methods.
PMID:29275251
Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites.
PMID:29106569
SABIO-RK: an updated resource for manually curated biochemical reaction kinetics.
PMID:29092055
A Protocol for Generating and Exchanging (Genome-Scale) Metabolic Resource Allocation Models.
PMID:28878200
Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology.
PMID:28725458
Cellular trade-offs and optimal resource allocation during cyanobacterial diurnal growth.
PMID:28720699
biochem4j: Integrated and extensible biochemical knowledge through graph databases.
PMID:28708831
SBMLmod: a Python-based web application and web service for efficient data integration and model simulation.
PMID:28646877
ChloroKB: A Web Application for the Integration of Knowledge Related to Chloroplast Metabolic Network.
PMID:28442501
Mathematical analysis of the influence of brain metabolism on the BOLD signal in Alzheimer's disease.
PMID:28271954
Protein Bioinformatics Databases and Resources.
PMID:28150231
Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks.
PMID:28114351
A genome-scale Escherichia coli kinetic metabolic model k-ecoli457 satisfying flux data for multiple mutant strains.
PMID:27996047
FAIRDOMHub: a repository and collaboration environment for sharing systems biology research.
PMID:27899646
Genome Sequence Variability Predicts Drug Precautions and Withdrawals from the Market.
PMID:27690231
The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable.
PMID:27051515
A physiome interoperability roadmap for personalized drug development.
PMID:27051513
ZBIT Bioinformatics Toolbox: A Web-Platform for Systems Biology and Expression Data Analysis.
PMID:26882475
Predictive Modeling of Drug Treatment in the Area of Personalized Medicine.
PMID:26692759
SBMLsqueezer 2: context-sensitive creation of kinetic equations in biochemical networks.
PMID:26452770
Diversity in protein domain superfamilies.
PMID:26451979
BioModels: Content, Features, Functionality, and Use.
PMID:26225232
SEEK: a systems biology data and model management platform.
PMID:26160520
kpath: integration of metabolic pathway linked data.
PMID:26055101
Mathematical modelling of metabolic regulation in aging.
PMID:25923415
Computationally Modeling Lipid Metabolism and Aging: A Mini-review.
PMID:25750699
Computational modeling of drug response with applications to neuroscience.
PMID:25733952
Quantitative and logic modelling of molecular and gene networks.
PMID:25645874
Synthetic biology outside the cell: linking computational tools to cell-free systems.
PMID:25538941
Self-organization of signal transduction.
PMID:25506419
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.
PMID:25503938
Predictive sulfur metabolism - a field in flux.
PMID:25477892
LigDig: a web server for querying ligand-protein interactions.
PMID:25433696
BioModels: ten-year anniversary.
PMID:25414348
BioModels linked dataset.
PMID:25182954
KiMoSys: a web-based repository of experimental data for KInetic MOdels of biological SYStems.
PMID:25115331
Text-mining-assisted biocuration workflows in Argo.
PMID:25037308
What mRNA Abundances Can Tell us about Metabolism.
PMID:24957650
Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.
PMID:24756107
Identification of key regulators in glycogen utilization in E. coli based on the simulations from a hybrid functional Petri net model.
PMID:24565082
The future of whole-cell modeling.
PMID:24556244
A systems' biology approach to study microRNA-mediated gene regulatory networks.
PMID:24350286
Path2Models: large-scale generation of computational models from biochemical pathway maps.
PMID:24180668
Function of dynamic models in systems biology: linking structure to behaviour.
PMID:24103739
Structure, function, and behaviour of computational models in systems biology.
PMID:23721297
Towards the collaborative curation of the registry underlying Identifiers.org.
PMID:23584831
Precise generation of systems biology models from KEGG pathways.
PMID:23433509
WholeCellKB: model organism databases for comprehensive whole-cell models.
PMID:23175606
Shrinking the metabolic solution space using experimental datasets.
PMID:22956899
Multiscale modeling and data integration in the virtual physiological rat project.
PMID:22805979