Three classes of epigenomic regulators converge to hyperactivate the essential maternal gene deadhead within a heterochromatin mini-domain.
PMID:34982772
Fitting thermodynamic-based models: Incorporating parameter sensitivity improves the performance of an evolutionary algorithm.
PMID:34687735
Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins.
PMID:32681087
Dissecting the sharp response of a canonical developmental enhancer reveals multiple sources of cooperativity.
PMID:31223115
Inference of Transcription Factor Regulation Patterns Using Gene Expression Covariation in Natural Populations of Drosophila melanogaster.
PMID:30739944
Spatially varying cis-regulatory divergence in Drosophila embryos elucidates cis-regulatory logic.
PMID:30383747
REDfly: the transcriptional regulatory element database for Drosophila.
PMID:30329093
Evidence for a hierarchical transcriptional circuit in Drosophila male germline involving testis-specific TAF and two gene-specific transcription factors, Mod and Acj6.
PMID:29235675
Characterization of dFOXO binding sites upstream of the Insulin Receptor P2 promoter across the Drosophila phylogeny.
PMID:29200426
Identification of cis-regulatory sequences reveals potential participation of lola and Deaf1 transcription factors in Anopheles gambiae innate immune response.
PMID:29028826
Stable Binding of the Conserved Transcription Factor Grainy Head to its Target Genes Throughout Drosophila melanogaster Development.
PMID:28007888
The caste- and sex-specific DNA methylome of the termite Zootermopsis nevadensis.
PMID:27848993
Data Integration for Microarrays: Enhanced Inference for Gene Regulatory Networks.
PMID:27600224
CLIMP: Clustering Motifs via Maximal Cliques with Parallel Computing Design.
PMID:27487245
Quantitative perturbation-based analysis of gene expression predicts enhancer activity in early Drosophila embryo.
PMID:27152947
Integration of Orthogonal Signaling by the Notch and Dpp Pathways in Drosophila.
PMID:26975664
ORegAnno 3.0: a community-driven resource for curated regulatory annotation.
PMID:26578589
Conservation of transcription factor binding specificities across 600 million years of bilateria evolution.
PMID:25779349
Incorporating chromatin accessibility data into sequence-to-expression modeling.
PMID:25762337
De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets.
PMID:25442502
Dynamic epigenetic control of highly conserved noncoding elements.
PMID:25289637
Evidence for deep regulatory similarities in early developmental programs across highly diverged insects.
PMID:25173756
The Groucho co-repressor is primarily recruited to local target sites in active chromatin to attenuate transcription.
PMID:25165826
Deciphering the combinatorial architecture of a Drosophila homeotic gene enhancer.
PMID:24514265
CCAT: Combinatorial Code Analysis Tool for transcriptional regulation.
PMID:24366875
OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites.
PMID:24271386
Under-dominance constrains the evolution of negative autoregulation in diploids.
PMID:23555226
Global analysis of Drosophila Cys₂-His₂ zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants.
PMID:23471540
Genome-wide screens for in vivo Tinman binding sites identify cardiac enhancers with diverse functional architectures.
PMID:23326246
CBS: an open platform that integrates predictive methods and epigenetics information to characterize conserved regulatory features in multiple Drosophila genomes.
PMID:23228284
Dissecting sources of quantitative gene expression pattern divergence between Drosophila species.
PMID:22893002
A complete workflow for the analysis of full-size ChIP-seq (and similar) data sets using peak-motifs.
PMID:22836136
The cis-regulatory code of Hox function in Drosophila.
PMID:22781127
Integrated genome analysis suggests that most conserved non-coding sequences are regulatory factor binding sites.
PMID:22684627
Novel miRNAs in the control of arsenite levels in rice.
PMID:22585409
Evolutionary origins of transcription factor binding site clusters.
PMID:22075113
Formation of regulatory modules by local sequence duplication.
PMID:21998564
Selection and constraint on regulatory elements in Drosophila simulans.
PMID:21904868
Improved accuracy of supervised CRM discovery with interpolated Markov models and cross-species comparison.
PMID:21821659
Genome-wide chromatin occupancy analysis reveals a role for ASH2 in transcriptional pausing.
PMID:21310711
Genome-wide profiling of forum domains in Drosophila melanogaster.
PMID:21247882
Predicting DNA-binding specificities of eukaryotic transcription factors.
PMID:21152420
Assessing computational methods of cis-regulatory module prediction.
PMID:21152003
FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system.
PMID:21097781
Scaffolding a Caenorhabditis nematode genome with RNA-seq.
PMID:20980554
REDfly v3.0: toward a comprehensive database of transcriptional regulatory elements in Drosophila.
PMID:20965965
The gap gene network.
PMID:20927566
Thermodynamics-based models of transcriptional regulation by enhancers: the roles of synergistic activation, cooperative binding and short-range repression.
PMID:20862354
Quantitative analysis of the Drosophila segmentation regulatory network using pattern generating potentials.
PMID:20808951
Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in Drosophila uncovers a regulatory basis for sensory specification.
PMID:20668662
Dinucleotide weight matrices for predicting transcription factor binding sites: generalizing the position weight matrix.
PMID:20339533
Functional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances.
PMID:20126523
Evolutionary mirages: selection on binding site composition creates the illusion of conserved grammars in Drosophila enhancers.
PMID:20107516
Statistical tests for natural selection on regulatory regions based on the strength of transcription factor binding sites.
PMID:19995462
A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data.
PMID:19956545
DISPARE: DIScriminative PAttern REfinement for Position Weight Matrices.
PMID:19941641
JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles.
PMID:19906716
Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function.
PMID:19758432
The complex spatio-temporal regulation of the Drosophila myoblast attractant gene duf/kirre.
PMID:19742310
BigFoot: Bayesian alignment and phylogenetic footprinting with MCMC.
PMID:19715598
Flynet: a genomic resource for Drosophila melanogaster transcriptional regulatory networks.
PMID:19656951
Alignment and prediction of cis-regulatory modules based on a probabilistic model of evolution.
PMID:19293946
Evolution of regulatory sequences in 12 Drosophila species.
PMID:19132088
Properties of non-coding DNA and identification of putative cis-regulatory elements in Theileria parva.
PMID:19055776
Quality of regulatory elements in Drosophila retrogenes.
PMID:18848618
PhyloGibbs-MP: module prediction and discriminative motif-finding by Gibbs sampling.
PMID:18769735
Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites.
PMID:18585360
Sepsid even-skipped enhancers are functionally conserved in Drosophila despite lack of sequence conservation.
PMID:18584029
Accelerated sequence divergence of conserved genomic elements in Drosophila melanogaster.
PMID:18583644
CSMET: comparative genomic motif detection via multi-resolution phylogenetic shadowing.
PMID:18535663
Positive and negative selection on noncoding DNA in Drosophila simulans.
PMID:18515263
A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system.
PMID:18332042
Text-mining assisted regulatory annotation.
PMID:18271954
Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.
PMID:18271625
Computational discovery of cis-regulatory modules in Drosophila without prior knowledge of motifs.
PMID:18226245
REDfly 2.0: an integrated database of cis-regulatory modules and transcription factor binding sites in Drosophila.
PMID:18039705
ORegAnno: an open-access community-driven resource for regulatory annotation.
PMID:18006570
MORPH: probabilistic alignment combined with hidden Markov models of cis-regulatory modules.
PMID:17997594
Reliable prediction of regulator targets using 12 Drosophila genomes.
PMID:17989251
Fine-tuning enhancer models to predict transcriptional targets across multiple genomes.
PMID:17973026
PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation.
PMID:17916232
Functional conservation of Rel binding sites in drosophilid genomes.
PMID:17785540
FlyMine: an integrated database for Drosophila and Anopheles genomics.
PMID:17615057
Improved benchmarks for computational motif discovery.
PMID:17559676
Large-scale analysis of transcriptional cis-regulatory modules reveals both common features and distinct subclasses.
PMID:17550599
STAMP: a web tool for exploring DNA-binding motif similarities.
PMID:17478497
Integrative content-driven concepts for bioinformatics "beyond the cell".
PMID:17426389
A core transcriptional network for early mesoderm development in Drosophila melanogaster.
PMID:17322403
Large-scale discovery of promoter motifs in Drosophila melanogaster.
PMID:17238282
SwissRegulon: a database of genome-wide annotations of regulatory sites.
PMID:17130146
Large-scale turnover of functional transcription factor binding sites in Drosophila.
PMID:17040121
Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments.
PMID:16904011
Fine scale structural variants distinguish the genomes of Drosophila melanogaster and D. pseudoobscura.
PMID:16872532
Stubb: a program for discovery and analysis of cis-regulatory modules.
PMID:16845069
Parametric alignment of Drosophila genomes.
PMID:16789815
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes.
PMID:16381825
Mapping Dmef2-binding regulatory modules by using a ChIP-enriched in silico targets approach.
PMID:16339902
Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content.
PMID:16086849
Ultraconserved elements in insect genomes: a highly conserved intronic sequence implicated in the control of homothorax mRNA splicing.
PMID:15899965
NestedMICA: sensitive inference of over-represented motifs in nucleic acid sequence.
PMID:15760844