Expression variations in ectodysplasin-A gene (eda) may contribute to morphological divergence of scales in haplochromine cichlids.
PMID:35272610
Experiment level curation of transcriptional regulatory interactions in neurodevelopment.
PMID:34665801
Many chronological aging clocks can be found throughout the epigenome: Implications for quantifying biological aging.
PMID:34655509
WEVar: a novel statistical learning framework for predicting noncoding regulatory variants.
PMID:34021560
Role of Myc Proto-Oncogene as a Transcriptional Hub to Regulate the Expression of Regeneration-Associated Genes following Preconditioning Peripheral Nerve Injury.
PMID:33262248
HAHmiR.DB: a server platform for high-altitude human miRNA-gene coregulatory networks and associated regulatory circuits.
PMID:33259604
LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies.
PMID:33055242
Critical Analysis of Genome-Wide Association Studies: Triple Negative Breast Cancer Quae Exempli Causa.
PMID:32823908
Signature-based approaches for informed drug repurposing: targeting CNS disorders.
PMID:32604402
Subacute cannabidiol alters genome-wide DNA methylation in adult mouse hippocampus.
PMID:32579259
Mapping and characterization of structural variation in 17,795 human genomes.
PMID:32460305
The TargetMine Data Warehouse: Enhancement and Updates.
PMID:31649722
Eric Davidson's Regulatory Genome for Computer Science: Causality, Logic, and Proof Principles of the Genomic cis-Regulatory Code.
PMID:31356126
Comprehensive mapping of the methylation landscape of 16 CpG-dense regions in oral and pharyngeal squamous cell carcinoma.
PMID:31215230
Myometrial Transcriptional Signatures of Human Parturition.
PMID:30988671
Investigation of somatic single nucleotide variations in human endogenous retrovirus elements and their potential association with cancer.
PMID:30934003
The rs61742690 (S783N) single nucleotide polymorphism is a suitable target for disrupting BCL11A-mediated foetal-to-adult globin switching.
PMID:30768627
In silico approach to identify non-synonymous SNPs with highest predicted deleterious effect on protein function in human obesity related gene, neuronal growth regulator 1 (NEGR1).
PMID:30402368
Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing.
PMID:30245013
Epigenome-Wide Analyses Identify Two Novel Associations With Recurrent Stroke in the Vitamin Intervention for Stroke Prevention Clinical Trial.
PMID:30237808
No Evidence for Recent Selection at FOXP2 among Diverse Human Populations.
PMID:30078708
Automatic extraction of protein-protein interactions using grammatical relationship graph.
PMID:30066644
Identifying noncoding risk variants using disease-relevant gene regulatory networks.
PMID:29453388
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.
PMID:29263835
A causal mediation model of ischemia reperfusion injury in the retina.
PMID:29121052
SalmoNet, an integrated network of ten Salmonella enterica strains reveals common and distinct pathways to host adaptation.
PMID:29057095
HTS-Net: An integrated regulome-interactome approach for establishing network regulation models in high-throughput screenings.
PMID:28949986
The Genetic Origin of Short Tail in Endangered Korean Dog, DongGyeongi.
PMID:28855671
COGNATE: comparative gene annotation characterizer.
PMID:28716078
Soft Sweeps Are the Dominant Mode of Adaptation in the Human Genome.
PMID:28482049
Identification of critical paralog groups with indispensable roles in the regulation of signaling flow.
PMID:27922122
Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a.
PMID:27909056
Evaluating tools for transcription factor binding site prediction.
PMID:27806697
Cross-species Conservation of context-specific networks.
PMID:27531214
DL-ADR: a novel deep learning model for classifying genomic variants into adverse drug reactions.
PMID:27510822
Inferring active regulatory networks from gene expression data using a combination of prior knowledge and enrichment analysis.
PMID:27295045
Predicting regulatory variants with composite statistic.
PMID:27273672
Combinatorial Gene Regulatory Functions Underlie Ultraconserved Elements in Drosophila.
PMID:27247329
rAAV-compatible MiniPromoters for restricted expression in the brain and eye.
PMID:27164903
Supporting community annotation and user collaboration in the integrated microbial genomes (IMG) system.
PMID:27118214
Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.
PMID:27078000
Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity.
PMID:27056836
An integrative data analysis platform for gene set analysis and knowledge discovery in a data warehouse framework.
PMID:26989145
Association of the IGF1 gene with fasting insulin levels.
PMID:26860063
Accelerated Evolution of Enhancer Hotspots in the Mammal Ancestor.
PMID:26715627
Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain.
PMID:26590212
DIANA-miRGen v3.0: accurate characterization of microRNA promoters and their regulators.
PMID:26586797
ORegAnno 3.0: a community-driven resource for curated regulatory annotation.
PMID:26578589
An integrated network platform for contextual prioritization of drugs and pathways.
PMID:26315485
Paired exome analysis of Barrett's esophagus and adenocarcinoma.
PMID:26192918
Novel therapeutics for coronary artery disease from genome-wide association study data.
PMID:26044129
Every Site Counts: Submitting Transcription Factor-Binding Site Information through the CollecTF Portal.
PMID:26013488
TFmiR: a web server for constructing and analyzing disease-specific transcription factor and miRNA co-regulatory networks.
PMID:25943543
Genome-wide identification of microRNA expression quantitative trait loci.
PMID:25791433
PreDREM: a database of predicted DNA regulatory motifs from 349 human cell and tissue samples.
PMID:25725063
Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling.
PMID:25679813
Autophagy Regulatory Network - a systems-level bioinformatics resource for studying the mechanism and regulation of autophagy.
PMID:25635527
Highly constrained intergenic Drosophila ultraconserved elements are candidate ncRNAs.
PMID:25618141
Type I diabetes mellitus: genetic factors and presumptive enteroviral etiology or protection.
PMID:25574400
GRASP v2.0: an update on the Genome-Wide Repository of Associations between SNPs and phenotypes.
PMID:25428361
Distinct roles for histone chaperones in the deposition of Htz1 in chromatin.
PMID:25338502
Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells.
PMID:25080971
Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
PMID:24951659
GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database.
PMID:24931982
Functional annotation signatures of disease susceptibility loci improve SNP association analysis.
PMID:24886216
Naturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancer.
PMID:24786295
Determining causality and consequence of expression quantitative trait loci.
PMID:24770875
Large-scale analysis of tandem repeat variability in the human genome.
PMID:24682812
Dissecting the causal genetic mechanisms of coronary heart disease.
PMID:24623178
Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration.
PMID:24550716
Candidate disease gene prediction using Gentrepid: application to a genome-wide association study on coronary artery disease.
PMID:24498628
RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization.
PMID:24478054
Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data.
PMID:24385916
Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development.
PMID:24378202
CollecTF: a database of experimentally validated transcription factor-binding sites in Bacteria.
PMID:24234444
Novel genes associated with colorectal cancer are revealed by high resolution cytogenetic analysis in a patient specific manner.
PMID:24204606
Sequence signatures extracted from proximal promoters can be used to predict distal enhancers.
PMID:24156763
Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort.
PMID:23981286
BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge.
PMID:23819467
Whole-genome sequence-based analysis of high-density lipoprotein cholesterol.
PMID:23770607
Detection and impact of rare regulatory variants in human disease.
PMID:23755067
GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications.
PMID:23723249
NRF2-ome: an integrated web resource to discover protein interaction and regulatory networks of NRF2.
PMID:23710289
RegTransBase--a database of regulatory sequences and interactions based on literature: a resource for investigating transcriptional regulation in prokaryotes.
PMID:23547897
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.
PMID:23525077
LASAGNA: a novel algorithm for transcription factor binding site alignment.
PMID:23522376
Using BioBin to explore rare variant population stratification.
PMID:23424138
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review.
PMID:23384594
SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks.
PMID:23331499
Patterns of methylation heritability in a genome-wide analysis of four brain regions.
PMID:23303775
Chapter 11: Genome-wide association studies.
PMID:23300413
An integrative approach to inferring gene regulatory module networks.
PMID:23285197
Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization.
PMID:23236496
HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions.
PMID:22900683
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
PMID:22610119
A machine learning approach for identifying novel cell type-specific transcriptional regulators of myogenesis.
PMID:22412381
Transcription factor binding site redundancy in embryonic enhancers of the Drosophila bithorax complex.
PMID:22384371
Fast, sensitive discovery of conserved genome-wide motifs.
PMID:22300316
TranscriptomeBrowser 3.0: introducing a new compendium of molecular interactions and a new visualization tool for the study of gene regulatory networks.
PMID:22292669
MotifMap: integrative genome-wide maps of regulatory motif sites for model species.
PMID:22208852
Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing.
PMID:22178994
Semantic annotation of biological concepts interplaying microbial cellular responses.
PMID:22122862
The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma.
PMID:22113997
Identification of cis-regulatory sequence variations in individual genome sequences.
PMID:21989199
Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death.
PMID:21957230
The NFI-Regulome Database: A tool for annotation and analysis of control regions of genes regulated by Nuclear Factor I transcription factors.
PMID:21884625
Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer.
PMID:21821674
Molecular dissection of cis-regulatory modules at the Drosophila bithorax complex reveals critical transcription factor signature motifs.
PMID:21821017
The mutational landscape of head and neck squamous cell carcinoma.
PMID:21798893
Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities.
PMID:21787409
Identifying functional single nucleotide polymorphisms in the human CArGome.
PMID:21771879
Integrated bio-entity network: a system for biological knowledge discovery.
PMID:21738677
Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome.
PMID:21602498
TargetMine, an integrated data warehouse for candidate gene prioritisation and target discovery.
PMID:21408081
Evolution of gene regulation of pluripotency--the case for wiki tracks at genome browsers.
PMID:21190561
Polycomb preferentially targets stalled promoters of coding and noncoding transcripts.
PMID:21177970
Genetic factors and diet affect long-bone length in the F34 LG,SM advanced intercross.
PMID:21170743
Patterns of human gene expression variance show strong associations with signaling network hierarchy.
PMID:21073694
Genomic differentiation between temperate and tropical Australian populations of Drosophila melanogaster.
PMID:21059887
Transcriptional regulation of mammalian miRNA genes.
PMID:20977933
Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data.
PMID:20808879
Identification of hookworm DAF-16/FOXO response elements and direct gene targets.
PMID:20808816
Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in Drosophila uncovers a regulatory basis for sensory specification.
PMID:20668662
PriorsEditor: a tool for the creation and use of positional priors in motif discovery.
PMID:20628076
Biomedical semantics: the hub for biomedical research 2.0.
PMID:20618983
Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profiling.
PMID:20478823
Most transcription factor binding sites are in a few mosaic classes of the human genome.
PMID:20459624
Semantic integration of data on transcriptional regulation.
PMID:20427517
Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling.
PMID:20421302
LINNAEUS: a species name identification system for biomedical literature.
PMID:20149233
Conserved elements associated with ribosomal genes and their trans-splice acceptor sites in Caenorhabditis elegans.
PMID:20100800
An effective tri-clustering algorithm combining expression data with gene regulation information.
PMID:19838334
Enhancing navigation in biomedical databases by community voting and database-driven text classification.
PMID:19799796
A protein-protein interaction guided method for competitive transcription factor binding improves target predictions.
PMID:19786498
Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention.
PMID:19704032
myGRN: a database and visualisation system for the storage and analysis of developmental genetic regulatory networks.
PMID:19500400
FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions.
PMID:19374773
Integrating sequence, evolution and functional genomics in regulatory genomics.
PMID:19226437
Caenorhabditis elegans cisRED: a catalogue of conserved genomic elements.
PMID:19151087
The UCSC Genome Browser Database: update 2009.
PMID:18996895
ConTra: a promoter alignment analysis tool for identification of transcription factor binding sites across species.
PMID:18453628
Text-mining assisted regulatory annotation.
PMID:18271954