MHC Restriction Ontology
Names
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MHC Restriction Ontology
metasource: Fairsharing.org
version: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
metasource: Biontology / Bioportal
version: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
MRO
metasource: Fairsharing.org
version: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
MHCRO
metasource: Biontology / Bioportal
version: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
Names
More detailed information about this field from each metasource.
MHC Restriction Ontology
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
metasource: Biontology / Bioportal
version: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
MRO
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
MHCRO
metasource: Biontology / Bioportalversion: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
Names
More detailed information about this field from each metasource.
MHC Restriction Ontology
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
metasource: Biontology / Bioportal
version: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
MRO
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
MHCRO
metasource: Biontology / Bioportalversion: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
MHC molecules form a highly diverse family of proteins that play a key role in cellular immune recognition. No consistent nomenclature exists across different vertebrate species. To correctly represent MHC related data in The Immune Epitope Database (IEDB), we built upon a previously established MHC ontology (MaHCO) and created MRO to represent MHC molecules as they relate to immunological experiments. MRO models MHC protein chains from 16 species, deals with different approaches used to identify MHC, such as direct sequencing verses serotyping, relates engineered MHC molecules to naturally occurring ones, connects genetic loci, alleles, protein chains and multichain proteins, and establishes evidence codes for MHC restriction.
Description
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MHC molecules form a highly diverse family of proteins that play a key role in cellular immune recognition. No consistent nomenclature exists across different vertebrate species. To correctly represent MHC related data in The Immune Epitope Database (IEDB), we built upon a previously established MHC ontology (MaHCO) and created MRO to represent MHC molecules as they relate to immunological experiments. MRO models MHC protein chains from 16 species, deals with different approaches used to identify MHC, such as direct sequencing verses serotyping, relates engineered MHC molecules to naturally occurring ones, connects genetic loci, alleles, protein chains and multichain proteins, and establishes evidence codes for MHC restriction.
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
The MHC Restriction Ontology (MRO) is an application ontology capturing how Major Histocompatibility Complex (MHC) restriction is defined in experiments, spanning exact protein complexes, individual protein chains, serotypes, haplotypes and mutant molecules, as well as evidence for MHC restrictions.
metasource: Biontology / Bioportalversion: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
Webpage:
https://github.com/IEDB/MROWebpage
More detailed information about this field from each metasource.
https://github.com/IEDB/MRO
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
metasource: Biontology / Bioportal
version: 2022-10-17 extracted_at: 2022-11-04T11:10:15.597147, http://bioportal.bioontology.org/ontologies/MHCRO
Licence:
Name: Creative Commons Attribution 3.0 Unported (CC BY 3.0)Licence name
More detailed information about this field from each metasource.
Creative Commons Attribution 3.0 Unported (CC BY 3.0)
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Licence URL
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https://creativecommons.org/licenses/by/3.0/
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
An ontology for major histocompatibility restriction
PMID: 26759709
metasource: Fairsharing.org
version: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Publications
More detailed information about this field from each metasource.
An ontology for major histocompatibility restriction
PMID: 26759709
metasource: Fairsharing.org
version: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
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An ontology for major histocompatibility restriction
PubMed citations: 11.
11 articles citing: An ontology for major histocompatibility restriction
Minimal Information about MHC Multimers (MIAMM). PMID:35042788
The Immune Epitope Database and Analysis Resource Program 2003-2018: reflections and outlook. PMID:31761977
Epitope Specific Antibodies and T Cell Receptors in the Immune Epitope Database. PMID:30515166
The Immune Epitope Database (IEDB): 2018 update. PMID:30357391
Identification of errors in the IEDB using ontologies. PMID:29688357
FAIR principles and the IEDB: short-term improvements and a long-term vision of OBO-foundry mediated machine-actionable interoperability. PMID:29688354
MIRO: guidelines for minimum information for the reporting of an ontology. PMID:29347969
Protein nanovaccine confers robust immunity against Toxoplasma. PMID:29263879
The Immune Epitope Database: How Data Are Entered and Retrieved. PMID:28634590
Better living through ontologies at the Immune Epitope Database. PMID:28365732
Thematic issue of the Second combined Bio-ontologies and Phenotypes Workshop. PMID:27955708
Tags:
Tags
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immune system
metasource: Fairsharing.org
version: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
major histocompatibility complex
metasource: Fairsharing.org
version: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Tags
More detailed information about this field from each metasource.
immune system
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
major histocompatibility complex
metasource: Fairsharing.orgversion: FAIRsharing.org: MRO; MHC Restriction Ontology; DOI: https://doi.org/10.25504/FAIRsharing.k893xa; Last edited: March 3, 2020, 1:13 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
immune system major histocompatibility complex
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