Kinase-Ligand Interaction Fingerprints and Structures database

Names

More detailed information about this field from each metasource. ×

Kinase-Ligand Interaction Fingerprints and Structures database

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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KLIFS

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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KLIFs

metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

---

klifs

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

Close

Other names: KLIFS, KLIFs, klifs

Kinase-Ligand Interaction Fingerprints and Structures database (KLIFS) is a database that revolves around the protein structure of catalytic kinase domains and the way kinase inhibitors can interact with them. Based on the underlying systematic and consistent protocol all (currently human and mouse) kinase structures and the binding mode of kinase ligands can be directly compared to each other. Moreover, because of the classification of an all-encompassing binding site of 85 residues it is possible to compare the interaction patterns of kinase-inhibitors to each other to, for example, identify crucial interactions determining kinase-inhibitor selectivity.

Webpage:

Licence:

Publications: (9)

Publications

More detailed information about this field from each metasource. ×

KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space
PMID: 23941661

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

---

KLIFS: a structural kinase-ligand interaction database
PMID: 26496949

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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The Landscape of Atypical and Eukaryotic Protein Kinases
PMID: 31677919

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

---

KLIFS: an overhaul after the first 5 years of supporting kinase research
PMID: 33084889

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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https://doi.org/10.1093/nar/gkaa895

metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

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http://dx.doi.org/10.1093/nar/gkaa895

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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http://dx.doi.org/10.1016/j.tips.2019.09.002

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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http://dx.doi.org/10.1021/jm400378w

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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http://dx.doi.org/10.1093/nar/gkv1082

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

Close

• KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space PubMed citations: 68.

  68 articles citing: KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space

  ×

  CavitySpace: A Database of Potential Ligand Binding Sites in the Human Proteome. PMID:35883523

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  Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2. PMID:35859885

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  RET kinase inhibitors for RET-altered thyroid cancers. PMID:35756966

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  Deciphering the conformational transitions of LIMK2 active and inactive states to ponder specific druggable states through microsecond scale molecular dynamics simulation. PMID:35652973

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  Pralsetinib: chemical and therapeutic development with FDA authorization for the management of RET fusion-positive non-small-cell lung cancers. PMID:35598228

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  Design, synthesis, and bioactivity evaluation of antitumor sorafenib analogues. PMID:35558629

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  TeachOpenCADD 2022: open source and FAIR Python pipelines to assist in structural bioinformatics and cheminformatics research. PMID:35524571

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  Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding? PMID:35226061

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  Profiling MAP kinase cysteines for targeted covalent inhibitor design. PMID:35224496

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  A Search for Cyclin-Dependent Kinase 4/6 Inhibitors by Pharmacophore-Based Virtual Screening, Molecular Docking, and Molecular Dynamic Simulations. PMID:34948218

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  Synthesis, In Vitro and In Silico Anticancer Activity of New 4-Methylbenzamide Derivatives Containing 2,6-Substituted Purines as Potential Protein Kinases Inhibitors. PMID:34884546

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  Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation. PMID:34827669

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  In Pursuit of an Allosteric Human Tropomyosin Kinase A (hTrkA) Inhibitor for Chronic Pain. PMID:34795875

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  Reactivities of the Front Pocket N-Terminal Cap Cysteines in Human Kinases. PMID:34647463

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  Kincore: a web resource for structural classification of protein kinases and their inhibitors. PMID:34643709

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  Cyclin-Dependent Kinase 4 and 6 Inhibitors in Cell Cycle Dysregulation for Breast Cancer Treatment. PMID:34361615

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  Rho-Kinase Inhibitors for the Treatment of Refractory Diabetic Macular Oedema. PMID:34359853

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  Aromatic Rings as Molecular Determinants for the Molecular Recognition of Protein Kinase Inhibitors. PMID:33810025

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  Molecular Targeting of Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor Receptor (VEGFR). PMID:33670650

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  Data set of competitive and allosteric protein kinase inhibitors confirmed by X-ray crystallography. PMID:33604432

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  Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening. PMID:33530327

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  Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets. PMID:33436888

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  Assessing the information content of structural and protein-ligand interaction representations for the classification of kinase inhibitor binding modes via machine learning and active learning. PMID:33431025

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  Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond. PMID:33410674

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  Nanomedicine of tyrosine kinase inhibitors. PMID:33408767

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  Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations. PMID:33161056

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  Diversity of Long-Lived Intermediates along the Binding Pathway of Imatinib to Abl Kinase Revealed by MD Simulations. PMID:33147951

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  Is Structure-Based Drug Design Ready for Selectivity Optimization? PMID:33119284

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  KLIFS: an overhaul after the first 5 years of supporting kinase research. PMID:33084889

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  Inhibitors of BRAF dimers using an allosteric site. PMID:32873792

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  Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources. PMID:32676006

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  Proposing the Promiscuous Protein Structures in JNK1 and JNK3 for Virtual Screening in Pursuit of Potential Leads. PMID:32149224

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  Identification of Druggable Kinase Target Conformations Using Markov Model Metastable States Analysis of apo-Abl. PMID:31999924

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  A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains. PMID:31875044

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  Advances in MS Based Strategies for Probing Ligand-Target Interactions: Focus on Soft Ionization Mass Spectrometric Techniques. PMID:31709232

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  Structure Based Design of Potent Selective Inhibitors of Protein Kinase D1 (PKD1). PMID:31531194

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  How Electrostatic Coupling Enables Conformational Plasticity in a Tyrosine Kinase. PMID:31476863

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  Encounter complexes and hidden poses of kinase-inhibitor binding on the free-energy landscape. PMID:31451651

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  Receptor-based pharmacophore modeling, virtual screening, and molecular docking studies for the discovery of novel GSK-3β inhibitors. PMID:31129879

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  Structural basis of resistance of mutant RET protein-tyrosine kinase to its inhibitors nintedanib and vandetanib. PMID:31118272

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  Assessing Lysine and Cysteine Reactivities for Designing Targeted Covalent Kinase Inhibitors. PMID:30945531

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  Defining a new nomenclature for the structures of active and inactive kinases. PMID:30867294

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  How to design potent and selective DYRK1B inhibitors? Molecular modeling study. PMID:30673861

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  KinaMetrix: a web resource to investigate kinase conformations and inhibitor space. PMID:30321373

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  Life beyond the Tanimoto coefficient: similarity measures for interaction fingerprints. PMID:30288626

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  Exploring Selectivity of Multikinase Inhibitors across the Human Kinome. PMID:30221217

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  Discovery and biological evaluation of N5-substituted 6,7-dioxo-6,7-dihydropteridine derivatives as potent Bruton's tyrosine kinase inhibitors. PMID:30108960

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  Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors. PMID:29937490

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  A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery. PMID:29737445

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  Prediction of sensitivity to gefitinib/erlotinib for EGFR mutations in NSCLC based on structural interaction fingerprints and multilinear principal component analysis. PMID:29514601

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  Prediction of Protein-compound Binding Energies from Known Activity Data: Docking-score-based Method and its Applications. PMID:29442436

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  3D-e-Chem: Structural Cheminformatics Workflows for Computer-Aided Drug Discovery. PMID:29337438

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  Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. PMID:29072804

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  Determining Cysteines Available for Covalent Inhibition Across the Human Kinome. PMID:28326775

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  Classifying kinase conformations using a machine learning approach. PMID:28152981

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  3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine. PMID:28125221

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  Quantitative Structure-activity Relationship (QSAR) Models for Docking Score Correction. PMID:28001004

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  Structural propensities of kinase family proteins from a Potts model of residue co-variation. PMID:27241634

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  Delineation of Polypharmacology across the Human Structural Kinome Using a Functional Site Interaction Fingerprint Approach. PMID:26929980

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  Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity. PMID:26895387

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  Recent Advances in the Development and Application of Radiolabeled Kinase Inhibitors for PET Imaging. PMID:26690113

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  KLIFS: a structural kinase-ligand interaction database. PMID:26496949

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  p38α MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening. PMID:26334265

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  Navigating into the binding pockets of the HER family protein kinases: discovery of novel EGFR inhibitor as antitumor agent. PMID:26229444

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  Fragment virtual screening based on Bayesian categorization for discovering novel VEGFR-2 scaffolds. PMID:26022686

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  Specificity rendering 'hot-spots' for aurora kinase inhibitor design: the role of non-covalent interactions and conformational transitions. PMID:25485544

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  Conformational analysis of the DFG-out kinase motif and biochemical profiling of structurally validated type II inhibitors. PMID:25478866

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  Exploration of type II binding mode: A privileged approach for kinase inhibitor focused drug discovery? PMID:24730530
• KLIFS: a structural kinase-ligand interaction database PubMed citations: 41.

  41 articles citing: KLIFS: a structural kinase-ligand interaction database

  ×

  Deciphering the conformational transitions of LIMK2 active and inactive states to ponder specific druggable states through microsecond scale molecular dynamics simulation. PMID:35652973

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  EMBER-Embedding Multiple Molecular Fingerprints for Virtual Screening. PMID:35216273

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  Fragment Hotspot Mapping to Identify Selectivity-Determining Regions between Related Proteins. PMID:35020376

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  2D SIFt: a matrix of ligand-receptor interactions. PMID:34496955

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  Trends in kinase drug discovery: targets, indications and inhibitor design. PMID:34354255

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  Kinase Inhibitors as Underexplored Antiviral Agents. PMID:33970631

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  A Crosstalk Between Dual-Specific Phosphatases and Dual-Specific Protein Kinases Can Be A Potential Therapeutic Target for Anti-cancer Therapy. PMID:33539023

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  Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening. PMID:33530327

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  Discovery of a novel kinase hinge binder fragment by dynamic undocking. PMID:33479656

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  Synthetic inhibitor leads of human tropomyosin receptor kinase A (hTrkA). PMID:33479642

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  Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets. PMID:33436888

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  Assessing the information content of structural and protein-ligand interaction representations for the classification of kinase inhibitor binding modes via machine learning and active learning. PMID:33431025

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  The structure-function relationship of oncogenic LMTK3. PMID:33188023

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  Is Structure-Based Drug Design Ready for Selectivity Optimization? PMID:33119284

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  Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3. PMID:33114754

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  KLIFS: an overhaul after the first 5 years of supporting kinase research. PMID:33084889

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  Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources. PMID:32676006

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  Targeting Receptor Tyrosine Kinase VEGFR-2 in Hepatocellular Cancer: Rational Design, Synthesis and Biological Evaluation of 1,2-Disubstituted Benzimidazoles. PMID:32053964

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  Druggable exosites of the human kino-pocketome. PMID:31925639

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  Insights into evolutionary interaction patterns of the 'Phosphorylation Activation Segment' in kinase. PMID:31787816

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  HKPocket: human kinase pocket database for drug design. PMID:31783725

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  Target-Specific Prediction of Ligand Affinity with Structure-Based Interaction Fingerprints. PMID:31381335

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  Kinase Atlas: Druggability Analysis of Potential Allosteric Sites in Kinases. PMID:31274316

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  Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology. PMID:31201557

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  Receptor-based pharmacophore modeling, virtual screening, and molecular docking studies for the discovery of novel GSK-3β inhibitors. PMID:31129879

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  Crystal structure of human vaccinia-related kinase 1 in complex with AMP-PNP, a non-hydrolyzable ATP analog. PMID:30461091

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  Life beyond the Tanimoto coefficient: similarity measures for interaction fingerprints. PMID:30288626

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  Exploring Selectivity of Multikinase Inhibitors across the Human Kinome. PMID:30221217

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  MEK inhibitors for the treatment of NRAS mutant melanoma. PMID:30154648

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  Structure-kinetic relationships that control the residence time of drug-target complexes: insights from molecular structure and dynamics. PMID:29986213

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  Redefining the Protein Kinase Conformational Space with Machine Learning. PMID:29861272

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  Kinase inhibitors: the road ahead. PMID:29545548

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  3D-e-Chem: Structural Cheminformatics Workflows for Computer-Aided Drug Discovery. PMID:29337438

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  The target landscape of clinical kinase drugs. PMID:29191878

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  Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. PMID:29072804

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  Insights into the binding mode of MEK type-III inhibitors. A step towards discovering and designing allosteric kinase inhibitors across the human kinome. PMID:28628649

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  Determining Cysteines Available for Covalent Inhibition Across the Human Kinome. PMID:28326775

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  Structural Analysis of Chemokine Receptor-Ligand Interactions. PMID:28165741

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  3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine. PMID:28125221

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  Function-specific virtual screening for GPCR ligands using a combined scoring method. PMID:27339552

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  Family-wide Structural Analysis of Human Numb-Associated Protein Kinases. PMID:26853940
• The Landscape of Atypical and Eukaryotic Protein Kinases PubMed citations: 20.

  20 articles citing: The Landscape of Atypical and Eukaryotic Protein Kinases

  ×

  A human kinase yeast array for the identification of kinases modulating phosphorylation-dependent protein-protein interactions. PMID:35225431

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  Innovations and Patent Trends in the Development of USFDA Approved Protein Kinase Inhibitors in the Last Two Decades. PMID:34451807

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  Unpicking the Roles of DNA Damage Protein Kinases in Trypanosomatids. PMID:34422791

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  Trends in kinase drug discovery: targets, indications and inhibitor design. PMID:34354255

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  Advances in chemical proteomic evaluation of lipid kinases-DAG kinases as a case study. PMID:34311404

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  Protein Kinases: Potential Drug Targets Against Schistosoma japonicum. PMID:34277472

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  Oncogenic dysregulation of pre-mRNA processing by protein kinases: challenges and therapeutic opportunities. PMID:34092037

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  Kinase Inhibitors as Underexplored Antiviral Agents. PMID:33970631

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  Adenosine triphosphate energy-independently controls protein homeostasis with unique structure and diverse mechanisms. PMID:33829608

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  Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities. PMID:33590753

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  Moonlighting Proteins Shine New Light on Molecular Signaling Niches. PMID:33573037

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  Exogenous bacterial DnaK increases protein kinases activity in human cancer cell lines. PMID:33563293

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  Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets. PMID:33436888

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  Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma. PMID:33392504

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  Functions and regulation of the serine/threonine protein kinase CK1 family: moving beyond promiscuity. PMID:33306089

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  Linker histone H1.5 is an underestimated factor in differentiation and carcinogenesis. PMID:33214908

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  Compounds from Natural Sources as Protein Kinase Inhibitors. PMID:33198400

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  KLIFS: an overhaul after the first 5 years of supporting kinase research. PMID:33084889

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  Molecular Basis for Ser/Thr Specificity in PKA Signaling. PMID:32630525

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  A Legionella effector kinase is activated by host inositol hexakisphosphate. PMID:32229585
• KLIFS: an overhaul after the first 5 years of supporting kinase research PubMed citations: 18.

  18 articles citing: KLIFS: an overhaul after the first 5 years of supporting kinase research

  ×

  Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2. PMID:35859885

  ---

  Deciphering the conformational transitions of LIMK2 active and inactive states to ponder specific druggable states through microsecond scale molecular dynamics simulation. PMID:35652973

  ---

  Creation of targeted compound libraries based on 3D shape recognition. PMID:35608807

  ---

  TeachOpenCADD 2022: open source and FAIR Python pipelines to assist in structural bioinformatics and cheminformatics research. PMID:35524571

  ---

  Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding? PMID:35226061

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  Structural Aspects of LIMK Regulation and Pharmacology. PMID:35011704

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  Fragment-to-Lead Medicinal Chemistry Publications in 2020. PMID:34928151

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  Allosteric Regulation of 3CL Protease of SARS-CoV-2 and SARS-CoV Observed in the Crystal Structure Ensemble. PMID:34717972

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  Kincore: a web resource for structural classification of protein kinases and their inhibitors. PMID:34643709

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  Biomolecule and Bioentity Interaction Databases in Systems Biology: A Comprehensive Review. PMID:34439912

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  Trends in kinase drug discovery: targets, indications and inhibitor design. PMID:34354255

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  Novel Compounds Targeting Neuropilin Receptor 1 with Potential To Interfere with SARS-CoV-2 Virus Entry. PMID:33787218

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  MCPdb: The bacterial microcompartment database. PMID:33780471

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  New 3-Aryl-2-(2-thienyl)acrylonitriles with High Activity Against Hepatoma Cells. PMID:33668139

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  Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening. PMID:33530327

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  Druggable Transient Pockets in Protein Kinases. PMID:33513739

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  Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets. PMID:33436888

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  The 2021 Nucleic Acids Research database issue and the online molecular biology database collection. PMID:33396976
• https://doi.org/10.1093/nar/gkaa895
Show more
http://dx.doi.org/10.1093/nar/gkaa895
http://dx.doi.org/10.1016/j.tips.2019.09.002
http://dx.doi.org/10.1021/jm400378w
http://dx.doi.org/10.1093/nar/gkv1082
Show less

Tags:

Tags

More detailed information about this field from each metasource. ×

binding

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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bioactivity

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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ligand

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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molecular interaction

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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multiple sequence alignment

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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protein

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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protein interaction

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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protein structure

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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structure alignment (pair)

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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structure-based sequence alignment

metasource: Fairsharing.org
version: FAIRsharing.org: KLIFS; Kinase-Ligand Interaction Fingerprints and Structures database; DOI: https://doi.org/10.25504/FAIRsharing.mihb12; Last edited: Nov. 9, 2020, 3:47 p.m.; Last accessed: Jan 03 2022 7:07 p.m.

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protein sequence databases

metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

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databases of individual protein families

metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

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chemical biology

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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cheminformatics

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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computational chemistry

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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drug discovery

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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medicinal chemistry

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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medicine

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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molecular interactions, pathways and networks

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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protein binding sites

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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protein interactions

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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protein sites, features and motifs

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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protein structure analysis

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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small molecules

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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structural biology

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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structural genomics

metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:08.660724

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binding bioactivity ligand molecular interaction multiple sequence alignment protein protein interaction protein structure structure alignment (pair) structure-based sequence alignment protein sequence protein family chemical biology cheminformatics computational chemistry drug discovery medicinal chemistry medicine molecular interactions, pathways and networks protein binding sites protein interaction protein sites, features and motifs protein structure analysis small molecule structural biology structural genomics