GENCODE

GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project. The GENCODE consortium was initially formed as part of the pilot phase of the ENCODE project to identify and map all protein-coding genes within the ENCODE regions (approx. 1% of Human genome). Given the initial success of the project, GENCODE now aims to build an “Encyclopedia of genes and genes variants” by identifying all gene features in the human and mouse genome using a combination of computational analysis, manual annotation, and experimental validation, and annotating all evidence-based gene features in the entire human genome at a high accuracy.

Webpage:

https://www.gencodegenes.org/

Licence:

Name: Copyrights
URL: https://www.gencodegenes.org/pages/data_access.html

Publications:

Publications
More detailed information about this field from each metasource.

The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
PMID: 22955988
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:07.713103

GENCODE: the reference human genome annotation for The ENCODE Project
PMID: 22955987
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:07.713103

GENCODE reference annotation for the human and mouse genomes
PMID: 30357393
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:07.713103

GENCODE 2021
PMID: 33270111
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:07.713103

The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression PubMed citations: 2369.

2369 articles citing: The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression

Identification of pyroptosis-related long non-coding RNAs with prognosis and therapy in lung squamous cell carcinoma. PMID:35778526
Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention. PMID:35773731
Identification, characterization and functional analysis of gonadal long noncoding RNAs in a protogynous hermaphroditic teleost fish, the ricefield eel (Monopterus albus). PMID:35725373
Identification of Long Noncoding RNAs Involved in Eyelid Pigmentation of Hereford Cattle. PMID:35601493
The Mechanism of Long Non-coding RNA in Cancer Radioresistance/Radiosensitivity: A Systematic Review. PMID:35600868
Systemically Silencing Long Non-coding RNAs Maclpil With Short Interfering RNA Nanoparticles Alleviates Experimental Ischemic Stroke by Promoting Macrophage Apoptosis and Anti-inflammatory Activation. PMID:35600488
Overexpressed lncRNA LINC00893 Suppresses Progression of Colon Cancer by Binding with miR-146b-3p to Upregulate PRSS8. PMID:35571488
Comparative Transcriptome Analysis Reveals Regulatory Mechanism of Long Non-Coding RNAs during Abdominal Preadipocyte Adipogenic Differentiation in Chickens. PMID:35565526
Long Non-Coding RNAs in Pancreatic Cancer: Biologic Functions, Mechanisms, and Clinical Significance. PMID:35565245
Circulating Noncoding RNAs in Pituitary Neuroendocrine Tumors-Two Sides of the Same Coin. PMID:35563510
Skin-Expressing lncRNAs in Inflammatory Responses. PMID:35559048
Retracted Article: Long non-coding RNA KCNQ1OT1 regulates cell proliferation, apoptosis and chemo-sensitivity through modulating the miR-186-5p/NCAM1 axis in acute myeloid leukemia cells. PMID:35540579
Epithelial-mesenchymal transition-related genes in coronary artery disease. PMID:35529472
Identification of novel key regulatory lncRNAs in gastric adenocarcinoma. PMID:35525925
Noncoding RNAs endogenously rule the cancerous regulatory realm while proteins govern the normal. PMID:35521545
Context-specific effects of sequence elements on subcellular localization of linear and circular RNAs. PMID:35513423
Long Non Coding RNA Based Regulation of Cerebrovascular Endothelium. PMID:35495157
N7-Methylguanosine-Related lncRNAs: Integrated Analysis Associated With Prognosis and Progression in Clear Cell Renal Cell Carcinoma. PMID:35495133
Placenta-specific lncRNA 1600012P17Rik is expressed in spongiotrophoblast and glycogen trophoblast cells of mouse placenta. PMID:35486179
Nucleic acid liquid biopsies in Alzheimer's disease: current state, challenges, and opportunities. PMID:35469332
Comparative Transcriptomics Reveals the Key lncRNA and mRNA of Sunite Sheep Adrenal Gland Affecting Seasonal Reproduction. PMID:35464356
Compartment-Specific Proximity Ligation Expands the Toolbox to Assess the Interactome of the Long Non-Coding RNA NEAT1. PMID:35457249
Evaluation of FMR4, FMR5 and FMR6 Expression Levels as Non-Invasive Biomarkers for the Diagnosis of Fragile X-Associated Primary Ovarian Insufficiency (FXPOI). PMID:35456280
New Insights into the Roles of lncRNAs as Modulators of Cytoskeleton Architecture and Their Implications in Cellular Homeostasis and in Tumorigenesis. PMID:35447891
Construction of a HOXA11-AS-Interact Ed Network in Keloid Fibroblasts Using Integrated Bioinformatic Analysis and in Vitro Validation. PMID:35432479
Non-coding RNAs: are they the protagonist or antagonist in the regulation of leukemia? PMID:35422954
Targeting non-coding RNAs to overcome cancer therapy resistance. PMID:35418578
Reshuffling of the ancestral core-eudicot genome shaped chromatin topology and epigenetic modification in Panax. PMID:35393424
Long noncoding RNA MALAT1 polymorphism predicts MACCEs in patients with myocardial infarction. PMID:35392816
SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylation. PMID:35387981
LncRNA HABON promoted liver cancer cells survival under hypoxia by inhibiting mPTP opening. PMID:35387966
circ_0000567/miR-421/TMEM100 Axis Promotes the Migration and Invasion of Lung Adenocarcinoma and Is Associated with Prognosis. PMID:35371319
The expression discrepancy and characteristics of long non-coding RNAs in peripheral blood leukocytes from amyotrophic lateral sclerosis patients. PMID:35364800
An Update of Long-Noncoding RNAs in Acute Kidney Injury. PMID:35350698
Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear. PMID:35338311
Obtaining Reliable RT-qPCR Results in Molecular Diagnostics-MIQE Goals and Pitfalls for Transcriptional Biomarker Discovery. PMID:35330136
Ribosome-Associated ncRNAs (rancRNAs) Adjust Translation and Shape Proteomes. PMID:35314615
The Role of Non-Coding RNAs in Autophagy During Carcinogenesis. PMID:35309939
Crucial Roles of miR-625 in Human Cancer. PMID:35308517
The long non-coding RNA UPAT promotes gastric cancer cell progression via UHRF1. PMID:35294719
The evolving role of long noncoding RNA HIF1A-AS2 in diabetic retinopathy: a cross-link axis between hypoxia, oxidative stress and angiogenesis via MAPK/VEGF-dependent pathway. PMID:35285425
Identification and Functional Analysis of lncRNA by CRISPR/Cas9 During the Cotton Response to Sap-Sucking Insect Infestation. PMID:35283887
Role of Nuclear Non-Canonical Nucleic Acid Structures in Organismal Development and Adaptation to Stress Conditions. PMID:35281835
An Evolutionarily Conserved AU-Rich Element in the 3' Untranslated Region of a Transcript Misannotated as a Long Noncoding RNA Regulates RNA Stability. PMID:35274990
Genetic variants associated mRNA stability in lung. PMID:35272635
Long non-coding RNA screening and identification of potential biomarkers for type 2 diabetes. PMID:35257412
Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology. PMID:35246252
Mammary epithelial cell transcriptome reveals potential roles of lncRNAs in regulating milk synthesis pathways in Jersey and Kashmiri cattle. PMID:35246027
Transcriptional kinetics and molecular functions of long noncoding RNAs. PMID:35241826
Long non-coding RNA HCG18 promotes gastric cancer progression by regulating miRNA-146a-5p/tumor necrosis factor receptor-associated factor 6 axis. PMID:35240920
Ion channel long non-coding RNAs in neuropathic pain. PMID:35235008
Novel long non-coding RNAs of relevance for ulcerative colitis pathogenesis. PMID:35224318
The lncRNA-AK046375 Upregulates Metallothionein-2 by Sequestering miR-491-5p to Relieve the Brain Oxidative Stress Burden after Traumatic Brain Injury. PMID:35222805
LncRNA Biomarkers of Inflammation and Cancer. PMID:35220568
Towards Molecular Mechanism in Long Non-coding RNAs: Linking Structure and Function. PMID:35220564
The Complexity of the Mammalian Transcriptome. PMID:35220563
Predictive role of ferroptosis-related long non-coding RNAs in bladder cancer and their association with immune microenvironment and immunotherapy response. PMID:35209909
Stage-Specific Non-Coding RNA Expression Patterns during In Vitro Human B Cell Differentiation into Antibody Secreting Plasma Cells. PMID:35202088
Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development. PMID:35198906
Does rapid sequence divergence preclude RNA structure conservation in vertebrates? PMID:35188540
The Role of ANRIL in Atherosclerosis. PMID:35186169
Inhibiting KDM6A Demethylase Represses Long Non-Coding RNA Hotairm1 Transcription in MDSC During Sepsis. PMID:35185915
Susceptibility Modules and Genes in Hypertrophic Cardiomyopathy by WGCNA and ceRNA Network Analysis. PMID:35178407
Evaluation of FOXCUT, CCAT2, and HULC LncRNA Expression Levels and Apoptosis Induction by Sodium Butyrate in PC-3 and LNCAP Prostate Cancer Cell Lines. PMID:35178357
Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors. PMID:35172143
E2F1-induced lncRNA, EMSLR regulates lncRNA LncPRESS1. PMID:35169159
A Transcriptome Analysis of mRNAs and Long Non-Coding RNAs in Patients with Parkinson's Disease. PMID:35163455
Crosstalk between Long Non Coding RNAs, microRNAs and DNA Damage Repair in Prostate Cancer: New Therapeutic Opportunities? PMID:35159022
Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression. PMID:35158906
Knockdown of lncRNA LINC00662 suppresses malignant behaviour of osteosarcoma cells via competition with miR-30b-3p to regulate ELK1 expression. PMID:35123530
LncRNA FENDRR-mediated tumor suppression and tumor-immune microenvironment changes in non-small cell lung cancer. PMID:35117761
A six-long noncoding RNA model predicts prognosis in lung adenocarcinoma. PMID:35117351
Non-Coding RNAs and Brain Tumors: Insights Into Their Roles in Apoptosis. PMID:35111757
Expression ratio of circular to linear ANRIL in hypertensive patients with coronary artery disease. PMID:35110626
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy. PMID:35110535
Genomic and functional conservation of lncRNAs: lessons from flies. PMID:35098341
The Role of the SOX9/lncRNA ANXA2P2/miR-361-3p/SOX9 Regulatory Loop in Cervical Cancer Cell Growth and Resistance to Cisplatin. PMID:35083143
Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics. PMID:35079163
Bioinformatics Analysis for the Roles of long non-coding RNAs in the Immune Responses of Mouse Peripheral Blood Mononuclear Cells Exposed to Low-Dose Ionizing Radiation. PMID:35069048
Molecular Mechanisms of lncRNAs in the Dependent Regulation of Cancer and Their Potential Therapeutic Use. PMID:35054945
The lncRNAs at X Chromosome Inactivation Center: Not Just a Matter of Sex Dosage Compensation. PMID:35054794
Experimental and Bioinformatic Approaches to Studying DNA Methylation in Cancer. PMID:35053511
Missing lnc(RNAs) in Alzheimer's Disease? PMID:35052379
LncRNAs at the heart of development and disease. PMID:35048139
Upregulation of the novel lncRNA U731166 is associated with migration, invasion and vemurafenib resistance in melanoma. PMID:35040264
An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs. PMID:35036870
Analysis of the circRNA and T-UCR populations identifies convergent pathways in mouse and human models of Rett syndrome. PMID:35036070
A chemoresistance lncRNA signature for recurrence risk stratification of colon cancer patients with chemotherapy. PMID:35036055
The new horizon of biomarker in melanoma patients: A study based on autophagy-related long non-coding RNA. PMID:35029926
New insights into the interplay between long non-coding RNAs and RNA-binding proteins in cancer. PMID:35019235
Linc01133 contributes to gastric cancer growth by enhancing YES1-dependent YAP1 nuclear translocation via sponging miR-145-5p. PMID:35017464
Bidirectional lncRNA Transfer between Cuscuta Parasites and Their Host Plant. PMID:35008986
Long non-coding RNA MALAT1 affects intermittent hypoxia-induced endothelial injury by regulating miR-142-3p/HMGB1. PMID:35006556
LncRNA Expression Profiles in Systemic Lupus Erythematosus and Rheumatoid Arthritis: Emerging Biomarkers and Therapeutic Targets. PMID:35003113
N7-methylguanosine modification of lncRNAs in a rat model of hypoxic pulmonary hypertension: a comprehensive analysis. PMID:34996349
Resveratrol inhibits cell apoptosis by suppressing long noncoding RNA (lncRNA) XLOC_014869 during lipopolysaccharide-induced acute lung injury in rats. PMID:34992821
Functional profiling of long intergenic non-coding RNAs in fission yeast. PMID:34984977
Novel insights into water-deficit-responsive mRNAs and lncRNAs during fiber development in Gossypium hirsutum. PMID:34979912
Long Non-coding RNA LOC285194 Promotes Epithelial Ovarian Cancer Progression via the Apoptosis Signaling Pathway. PMID:34972707
A Brief Overview of lncRNAs in Endothelial Dysfunction-Associated Diseases: From Discovery to Characterization. PMID:34968230
LncRNAs and PRC2: Coupled Partners in Embryonic Stem Cells. PMID:34968226
Small Molecule Drugs Targeting Non-Coding RNAs as Treatments for Alzheimer's Disease and Related Dementias. PMID:34946953
Competitive Endogenous RNA Network Involving miRNA and lncRNA in Non-Hodgkin Lymphoma: Current Advances and Clinical Perspectives. PMID:34944752
Human rDNA and Cancer. PMID:34943960
What is beyond LncRNAs in breast cancer: A special focus on colon cancer-associated Transcript-1 (CCAT-1). PMID:34938928
Lnc-C2orf63-4-1 Confers VSMC Homeostasis and Prevents Aortic Dissection Formation via STAT3 Interaction. PMID:34938738
Long Non-Coding RNA Neighbor of BRCA1 Gene 2: A Crucial Regulator in Cancer Biology. PMID:34926299
Evolving features of human cortical development and the emerging roles of non-coding RNAs in neural progenitor cell diversity and function. PMID:34921638
Identification of Gm15441, a Txnip antisense lncRNA, as a critical regulator in liver metabolic homeostasis. PMID:34906243
Functional Peptides Encoded by Long Non-Coding RNAs in Gastrointestinal Cancer. PMID:34888249
Gestational Age Dependence of the Maternal Circulating Long Non-Coding RNA Transcriptome During Normal Pregnancy Highlights Antisense and Pseudogene Transcripts. PMID:34880903
Emerging Impact of Non-coding RNAs in the Pathology of Stroke. PMID:34867304
Human brain evolution: Emerging roles for regulatory DNA and RNA. PMID:34861533
Long non-coding RNAs as possible therapeutic targets in protozoa, and in Schistosoma and other helminths. PMID:34859292
Long Noncoding RNAs Involved in Cardiomyocyte Apoptosis Triggered by Different Stressors. PMID:34855148
Development of epithelial-mesenchymal transition-related lncRNA signature for predicting survival and immune microenvironment in pancreatic cancerwithexperiment validation. PMID:34854360
Microproteins in skeletal muscle: hidden keys in muscle physiology. PMID:34850602
Between the Devil and the Deep Blue Sea: Non-Coding RNAs Associated with Transmissible Cancers in Tasmanian Devil, Domestic Dog and Bivalves. PMID:34842768
Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae. PMID:34831396
Non-Coding RNAs in Response to Drought Stress. PMID:34830399
Long Non-Coding RNAs Associated with Ribosomes in Human Adipose-Derived Stem Cells: From RNAs to Microproteins. PMID:34827671
Long Non-Coding RNAs in Epithelial-Mesenchymal Transition of Pancreatic Cancer. PMID:34820419
Xist nucleates local protein gradients to propagate silencing across the X chromosome. PMID:34813726
Application of RNA subcellular fraction estimation method to explore RNA localization regulation. PMID:34791188
A narrative review of prognosis prediction models for non-small cell lung cancer: what kind of predictors should be selected and how to improve models? PMID:34790803
Maximizing the Utility of Transcriptomics Data in Inflammatory Skin Diseases. PMID:34777377
LncRNAs in domesticated animals: from dog to livestock species. PMID:34773482
Emerging Role of Non-coding RNAs in Autism Spectrum Disorder. PMID:34767189
The Role of Long Non-coding RNAs in Human Imprinting Disorders: Prospective Therapeutic Targets. PMID:34760887
LncRNAWiki 2.0: a knowledgebase of human long non-coding RNAs with enhanced curation model and database system. PMID:34751395
Dual regulatory actions of LncBMP4 on BMP4 promote chicken primordial germ cell formation. PMID:34747116
What sequencing technologies can teach us about innate immunity. PMID:34747035
High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68. PMID:34743709
Molecular characterization of metabolic subtypes of gastric cancer based on metabolism-related lncRNA. PMID:34728653
Epigenetic interaction of microbes with their mammalian hosts. PMID:34728591
Identifying long non-coding RNAs and characterizing their functional roles in swine mammary gland from colostrogenesis to lactogenesis. PMID:34727649
PRNCR1: a long non-coding RNA with a pivotal oncogenic role in cancer. PMID:34727260
Development of a prognostic signature of patients with esophagus adenocarcinoma by using immune-related genes. PMID:34724890
LncRNA GAPLINC Promotes Renal Cell Cancer Tumorigenesis by Targeting the miR-135b-5p/CSF1 Axis. PMID:34722262
Complex Age- and Cancer-Related Changes in Human Blood Transcriptome-Implications for Pan-Cancer Diagnostics. PMID:34721535
Cis-acting super-enhancer lncRNAs as biomarkers to early-stage breast cancer. PMID:34717732
A Review on the Carcinogenic Roles of DSCAM-AS1. PMID:34708048
Silencing of LncRNA AFAP1-AS1 Inhibits Cell Proliferation in Oral Squamous Cancer by Suppressing CCNA2. PMID:34703311
Differential Allelic Expression among Long Non-Coding RNAs. PMID:34698262
Insights Into mRNA and Long Non-coding RNA Profiling RNA Sequencing in Uterus of Chickens With Pink and Blue Eggshell Colors. PMID:34692811
Biological Roles and Clinical Significance of Exosome-Derived Noncoding RNAs in Bladder Cancer. PMID:34692482
(In)Distinctive Role of Long Non-Coding RNAs in Common and Rare Ovarian Cancers. PMID:34680193
Analysis of mRNA and Long Non-Coding RNA Expression Profiles in Developing Yorkshire Pig Spleens. PMID:34679790
Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors. PMID:34676924
A mechanistic view of long noncoding RNAs in cancer. PMID:34668345
The transcribed ultraconserved region uc.160+ enhances processing and A-to-I editing of the miR-376 cluster: hypermethylation improves glioma prognosis. PMID:34665919
Sequence complementarity between human noncoding RNAs and SARS-CoV-2 genes: What are the implications for human health? PMID:34662705
Identification of long noncoding RNAs in injury-resilient and injury-susceptible mouse retinal ganglion cells. PMID:34649511
Getting to the bottom of lncRNA mechanism: structure-function relationships. PMID:34642784
RNA Deregulation in Amyotrophic Lateral Sclerosis: The Noncoding Perspective. PMID:34638636
The Functional Role of Long Non-Coding RNAs in Melanoma. PMID:34638331
Long noncoding RNAs: fine-tuners hidden in the cancer signaling network. PMID:34635646
Single-Cell RNA Sequencing (scRNA-seq) in Cardiac Tissue: Applications and Limitations. PMID:34629873
Testis transcriptome profiling identified lncRNAs involved in spermatogenic arrest of cattleyak. PMID:34626308
GAS5 rs2067079 and miR-137 rs1625579 functional SNPs and risk of chronic hepatitis B virus infection among Egyptian patients. PMID:34625583
SINEUPs: a novel toolbox for RNA therapeutics. PMID:34623427
The Perspective of Dysregulated LncRNAs in Alzheimer's Disease: A Systematic Scoping Review. PMID:34621163
lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus. PMID:34608273
Multidimensional Mechanistic Spectrum of Long Non-coding RNAs in Heart Development and Disease. PMID:34604357
Transcriptome Analysis Revealed Potential Mechanisms of Resistance to Trichomoniasis gallinae Infection in Pigeon (Columba livia). PMID:34595226
Long Noncoding RNAs Regulate the Radioresistance of Breast Cancer. PMID:34595090
The role of long non-coding RNAs in the regulation of pancreatic beta cell identity. PMID:34581756
High frequency of intron retention and clustered H3K4me3-marked nucleosomes in short first introns of human long non-coding RNAs. PMID:34579770
The Role of lncRNAs in Rare Tumors with a Focus on HOX Transcript Antisense RNA (HOTAIR). PMID:34576322
Identification of Abundant and Functional dodecaRNAs (doRNAs) Derived from Ribosomal RNA. PMID:34575920
Non-Coding RNA in Systemic Sclerosis: A Valuable Tool for Translational and Personalized Medicine. PMID:34573278
Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. PMID:34556693
Designing libraries for pooled CRISPR functional screens of long noncoding RNAs. PMID:34533605
A putative role for lncRNAs in epigenetic regulation of memory. PMID:34530054
Long Non-coding RNAs in Pathogenesis of Neurodegenerative Diseases. PMID:34527672
MyoData: An expression knowledgebase at single cell/nucleus level for the discovery of coding-noncoding RNA functional interactions in skeletal muscle. PMID:34527188
Long noncoding RNA and protein abundance in lncRNPs. PMID:34526358
Non-coding RNAs in depression: Promising diagnostic and therapeutic biomarkers. PMID:34521053
Comprehensive analysis of lncRNAs as biomarkers for diagnosis, prognosis, and treatment response in clear cell renal cell carcinoma. PMID:34514100
Effect of Aberrant Long Noncoding RNA on the Prognosis of Clear Cell Renal Cell Carcinoma. PMID:34512796
Epigenetic Regulation of the Vascular Endothelium by Angiogenic LncRNAs. PMID:34512715
A Novel Regulatory Player in the Innate Immune System: Long Non-Coding RNAs. PMID:34502451
Non-Coding RNAs in Normal B-Cell Development and in Mantle Cell Lymphoma: From Molecular Mechanism to Biomarker and Therapeutic Agent Potential. PMID:34502399
Noncoding RNAs in tumor metastasis: molecular and clinical perspectives. PMID:34499209
The noncoding genome and hearing loss. PMID:34491412
Identification of a Novel Glycolysis-Related LncRNA Signature for Predicting Overall Survival in Patients With Bladder Cancer. PMID:34490046
Prominence of urinary biomarkers for bladder cancer in the COVID-19 era: From the commercially available to new prospective candidates. PMID:34488250
Cap analysis of gene expression (CAGE) and noncoding regulatory elements. PMID:34468849
lncExplore: a database of pan-cancer analysis and systematic functional annotation for lncRNAs from RNA-sequencing data. PMID:34464437
RP11-616M22.7 recapitulates imatinib resistance in gastrointestinal stromal tumor. PMID:34458010
The Emerging Landscapes of Long Noncoding RNA in Thyroid Carcinoma: Biological Functions and Clinical Significance. PMID:34447696
Investigation of LINC00493/SMIM26 Gene Suggests Its Dual Functioning at mRNA and Protein Level. PMID:34445188
Role of Long Non-Coding RNAs in Pulmonary Arterial Hypertension. PMID:34440661
Long Non-Coding RNAs Involved in Progression of Non-Alcoholic Fatty Liver Disease to Steatohepatitis. PMID:34440652
The role of the multifaceted long non-coding RNAs: A nuclear-cytosolic interplay to regulate hyaluronan metabolism. PMID:34435179
CCAT1/FABP5 promotes tumour progression through mediating fatty acid metabolism and stabilizing PI3K/AKT/mTOR signalling in lung adenocarcinoma. PMID:34431227
ELF3-AS1 contributes to gastric cancer progression by binding to hnRNPK and induces thrombocytosis in peripheral blood. PMID:34418240
Long Noncoding RNAs: An Overview. PMID:34417759
Illuminating lncRNA Function Through Target Prediction. PMID:34417758
Characterizing miRNA-lncRNA Interplay. PMID:34417757
Purification and Structural Characterization of the Long Noncoding RNAs. PMID:34417746
Long Non-coding RNA Expression Profiling Using Arraystar LncRNA Microarrays. PMID:34417743
Detection of Long Noncoding RNA Expression by Real-Time PCR. PMID:34417741
The epigenetic mechanisms involved in mitochondrial dysfunction: Implication for Parkinson's disease. PMID:34414627
Long noncoding RNA landscapes specific to benign and malignant thyroid neoplasms of distinct histological subtypes. PMID:34408227
Significance of lncRNA abundance to function. PMID:34406447
Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brain. PMID:34400477
Immunomodulatory Role and Therapeutic Potential of Non-Coding RNAs Mediated by Dendritic Cells in Autoimmune and Immune Tolerance-Related Diseases. PMID:34394079
Comment on "Altered Expression of Long Non-coding RNAs in Peripheral Blood Mononuclear Cells of Patients with Alzheimer's Disease". PMID:34390470
Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells. PMID:34390351
MicroRNA-1205 Regulation of FRYL in Prostate Cancer. PMID:34386489
Long Non-coding RNA: An Emerging Contributor and Potential Therapeutic Target in Renal Fibrosis. PMID:34386039
Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors. PMID:34385467
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation. PMID:34375583
Long Non-coding RNA Signatures Associated With Liver Aging in Senescence-Accelerated Mouse Prone 8 Model. PMID:34368149
From Micro to Long: Non-Coding RNAs in Tamoxifen Resistance of Breast Cancer Cells. PMID:34359587
Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profiles in Testes of Calves and Sexually Mature Wandong Bulls (Bos taurus). PMID:34359134
From Junk to Function: LncRNAs in CNS Health and Disease. PMID:34349622
Novel role of long non-coding RNAs in autoimmune cutaneous disease. PMID:34346026
Quantification of long non-coding RNAs using qRT-PCR: comparison of different cDNA synthesis methods and RNA stability. PMID:34336028
Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts. PMID:34330918
The Indirect Antiviral Potential of Long Noncoding RNAs Encoded by IFITM Pseudogenes. PMID:34319781
Cancer LncRNA Census 2 (CLC2): an enhanced resource reveals clinical features of cancer lncRNAs. PMID:34316704
Long non-coding RNAs in brain tumors. PMID:34316694
A genetic variant alters the secondary structure of the lncRNA H19 and is associated with dilated cardiomyopathy. PMID:34313541
Role of Long Non-Coding RNAs and the Molecular Mechanisms Involved in Insulin Resistance. PMID:34298896
Large-Scale Transcriptomics-Driven Approach Revealed Overexpression of CRNDE as a Poor Survival Prognosis Biomarker in Glioblastoma. PMID:34298634
Web tools to perform long non-coding RNAs analysis in oncology research. PMID:34296748
Long Non-Coding RNAs in the Tumor Immune Microenvironment: Biological Properties and Therapeutic Potential. PMID:34295338
Identification and expression analysis of lncRNA in seven organs of Rhinopithecus roxellana. PMID:34291340
KDM6A Lysine Demethylase Directs Epigenetic Polarity of MDSCs during Murine Sepsis. PMID:34289476
Long non‑coding RNA LINC01224 promotes cell proliferation and inhibits apoptosis by regulating AKT3 expression via targeting miR‑485‑5p in endometrial carcinoma. PMID:34278482
Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation. PMID:34266873
RNA-Seq Data for Reliable SNP Detection and Genotype Calling: Interest for Coding Variant Characterization and Cis-Regulation Analysis by Allele-Specific Expression in Livestock Species. PMID:34262593
JEDI: circular RNA prediction based on junction encoders and deep interaction among splice sites. PMID:34252942
The Role of microRNAs and Long Non-Coding RNAs in the Regulation of the Immune Response to Mycobacterium tuberculosis Infection. PMID:34248974
Potential impact and mechanism of Long Non-coding RNAs on cancer and associated T cells. PMID:34234857
Emerging Role of Long Non-Coding RNAs in Diabetic Vascular Complications. PMID:34234740
Comprehensive Analysis of lncRNA and miRNA Regulatory Network Reveals Potential Prognostic Non-coding RNA Involved in Breast Cancer Progression. PMID:34220926
Characterization of a ferroptosis and iron-metabolism related lncRNA signature in lung adenocarcinoma. PMID:34217273
Long noncoding RNA uc003pxg.1 regulates endothelial cell proliferation and migration via miR‑25‑5p in coronary artery disease. PMID:34212983
Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons. PMID:34210972
The lncRNAs in HBV-Related HCCs: Targeting Chromatin Dynamics and Beyond. PMID:34206504
Integrated Insight into the Molecular Mechanisms of Spontaneous Abortion during Early Pregnancy in Pigs. PMID:34205766
Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders. PMID:34204536
Brain Long Noncoding RNAs: Multitask Regulators of Neuronal Differentiation and Function. PMID:34203457
Interactions among Long Non-Coding RNAs and microRNAs Influence Disease Phenotype in Diabetes and Diabetic Kidney Disease. PMID:34199672
Genome-Wide Characterization and Identification of Long Non-Coding RNAs during the Molting Process of a Spider Mite, Panonychus citri. PMID:34199120
siRNAs Targeting Mouse-Specific lncRNA AA388235 Induce Human Tumor Cell Pyroptosis/Apoptosis. PMID:34195074
Identification of Regulatory Functions of LncRNAs Associated With T. circumcincta Infection in Adult Sheep. PMID:34194481
Cytoplasmic long noncoding RNAs are differentially regulated and translated during human neuronal differentiation. PMID:34193551
Biological Function of Long Non-coding RNA (LncRNA) Xist. PMID:34178980
Roles of Long Noncoding RNAs in Conferring Glioma Progression and Treatment. PMID:34178684
Identification and Analysis of Long Non-coding RNAs in Leuciscus waleckii Adapted to Highly Alkaline Conditions. PMID:34177616
Blood-Based Biomarkers: A Forgotten Friend of Hyperacute Ischemic Stroke. PMID:34168606
Genome-wide binding analysis of 195 DNA binding proteins reveals "reservoir" promoters and human specific SVA-repeat family regulation. PMID:34166368
Pseudogenes: A Novel Source of Trans-Acting Antisense RNAs. PMID:34165718
Empirical Validation of Overlapping Virus lncRNAs and Coding Transcripts by Northern Blot. PMID:34160812
Measuring lncRNA Expression by Real-Time PCR. PMID:34160801
LncRNA as Cancer Biomarkers. PMID:34160797
LncRNAs and Available Databases. PMID:34160796
RNA Network Interactions During Differentiation of Human Trophoblasts. PMID:34150771
Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units. PMID:34141143
A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription. PMID:34140474
A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA. PMID:34131282
Deeply Mining a Universe of Peptides Encoded by Long Noncoding RNAs. PMID:34129944
The Use of Zebrafish Xenotransplant Assays to Analyze the Role of lncRNAs in Breast Cancer. PMID:34123857
Timing without coding: How do long non-coding RNAs regulate circadian rhythms? PMID:34116930
Identification and characterization of lncRNA AP000253 in occult hepatitis B virus infection. PMID:34112188
Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3. PMID:34111112
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity. PMID:34107378
Integrated Analysis of Long Noncoding RNA Expression Profiles in Acute-on-Chronic Liver Failure. PMID:34104647
Investigation of lncRNA-mRNA co-expression network in ETV6-RUNX1-positive pediatric B-cell acute lymphoblastic leukemia. PMID:34101758
Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway. PMID:34096602
lncRNA TRMP-S directs dual mechanisms to regulate p27-mediated cellular senescence. PMID:34094715
The pleiotropic roles of circular and long noncoding RNAs in cutaneous melanoma. PMID:34080276
Downregulation of lncRNA XR_429159.1 Linked to Brain Metastasis in Patients With Limited-Stage Small-Cell Lung Cancer. PMID:34079751
Methylation and Noncoding RNAs in Gastric Cancer: Everything Is Connected. PMID:34073603
Decoding LncRNAs. PMID:34072257
The Landscape of lncRNAs in Hepatocellular Carcinoma: A Translational Perspective. PMID:34071216
Mechanisms of TP53 Pathway Inactivation in Embryonic and Somatic Cells-Relevance for Understanding (Germ Cell) Tumorigenesis. PMID:34065345
LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis. PMID:34056831
Long Non-coding RNA RUNDC3A-AS1 Promotes Lung Metastasis of Thyroid Cancer via Targeting the miR-182-5p/ADAM9. PMID:34046406
The transcriptomic response to heat stress of a jujube (Ziziphus jujuba Mill.) cultivar is featured with changed expression of long noncoding RNAs. PMID:34043642
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia. PMID:34040147
Long non-coding RNAs in Epstein-Barr virus-related cancer. PMID:34034760
Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with hepatocellular carcinoma. PMID:34027555
TCONS_00230836 silencing restores stearic acid-induced β cell dysfunction through alleviating endoplasmic reticulum stress rather than apoptosis. PMID:34022799
Transcriptome analysis reveals potential function of long non-coding RNAs in 20-hydroxyecdysone regulated autophagy in Bombyx mori. PMID:34022797
Natural antisense transcript of Period2, Per2AS, regulates the amplitude of the mouse circadian clock. PMID:34016691
Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans. PMID:34016118
In vivo discovery of RNA proximal proteins via proximity-dependent biotinylation. PMID:34006179
Generation of an isoform-level transcriptome atlas of macrophage activation. PMID:34000296
LncRNAs associated with glioblastoma: From transcriptional noise to novel regulators with a promising role in therapeutics. PMID:33996255
Reconstruction and Analysis of the Immune-Related LINC00987/A2M Axis in Lung Adenocarcinoma. PMID:33987201
Long noncoding RNA LINC01296 plays an oncogenic role in colorectal cancer by suppressing p15 expression. PMID:33983053
Four long noncoding RNAs act as biomarkers in lung adenocarcinoma. PMID:33981850
Identification of Long Non-coding RNA Isolated From Naturally Infected Macrophages and Associated With Bovine Johne's Disease in Canadian Holstein Using a Combination of Neural Networks and Logistic Regression. PMID:33969037
Non-Coding RNAs Regulate Placental Trophoblast Function and Participate in Recurrent Abortion. PMID:33967782
CRISPR screen in cancer: status quo and future perspectives. PMID:33948344
lncRNA PVT1 in the Pathogenesis and Clinical Management of Renal Cell Carcinoma. PMID:33947142
HIV-1 Natural Antisense Transcription and Its Role in Viral Persistence. PMID:33946840
Long Noncoding RNA Fos Downstream Transcript Is Developmentally Dispensable but Vital for Shaping the Poststroke Functional Outcome. PMID:33940958
Unresolved Issues in RNA Therapeutics in Vascular Diseases With a Focus on Aneurysm Disease. PMID:33937351
Long Intergenic Non-Coding RNAs in the Mammary Parenchyma and Fat Pad of Pre-Weaning Heifer Calves: Identification and Functional Analysis. PMID:33924848
The Role of lncRNAs in the Pathobiology and Clinical Behavior of Multiple Myeloma. PMID:33923983
Long Non-Coding RNAs in Insects. PMID:33919662
Novel lincRNA Discovery and Tissue-Specific Gene Expression across 30 Normal Human Tissues. PMID:33919168
The prognostic value of an autophagy-related lncRNA signature in hepatocellular carcinoma. PMID:33910497
The emerging regulatory roles of noncoding RNAs in immune function of fish: MicroRNAs versus long noncoding RNAs. PMID:33904988
The role of long noncoding RNAs in livestock adipose tissue deposition - A review. PMID:33902176
The nuclear functions of long noncoding RNAs come into focus. PMID:33898883
RNAs as Regulators of Cellular Matchmaking. PMID:33898516
Identification of Epithelial-Mesenchymal Transition-Related lncRNAs that Associated With the Prognosis and Immune Microenvironment in Colorectal Cancer. PMID:33898515
Comparative genomics in the search for conserved long noncoding RNAs. PMID:33885137
Transcriptomic analysis to infer key molecular players involved during host response to NDV challenge in Gallus gallus (Leghorn & Fayoumi). PMID:33875770
The control of polycomb repressive complexes by long noncoding RNAs. PMID:33861025
Long Noncoding RNAs and Their Therapeutic Promise in Diabetic Nephropathy. PMID:33853077
A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1. PMID:33851096
Whole-Transcriptome RNA Sequencing Reveals Significant Differentially Expressed mRNAs, miRNAs, and lncRNAs and Related Regulating Biological Pathways in the Peripheral Blood of COVID-19 Patients. PMID:33833618
The Impact of lncRNAs in Diabetes Mellitus: A Systematic Review and In Silico Analyses. PMID:33815273
miRNAs and lncRNAs as Novel Therapeutic Targets to Improve Cancer Immunotherapy. PMID:33808190
Long, Noncoding RNA Dysregulation in Glioblastoma. PMID:33807183
CALINCA-A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease. PMID:33804736
Approaches to Identify and Characterise the Post-Transcriptional Roles of lncRNAs in Cancer. PMID:33803328
Genome-Wide Identification and Characterization of Long Noncoding RNAs Involved in Chinese Wheat Mosaic Virus Infection of Nicotiana benthamiana. PMID:33802832
Foam Cells as Therapeutic Targets in Atherosclerosis with a Focus on the Regulatory Roles of Non-Coding RNAs. PMID:33802600
Long Noncoding RNAs-Crucial Players Organizing the Landscape of the Neuronal Nucleus. PMID:33801737
Non-Coding RNA Signatures of B-Cell Acute Lymphoblastic Leukemia. PMID:33799946
Antisense RNAs during early vertebrate development are divided in groups with distinct features. PMID:33795334
Integrated analysis of lncRNA, miRNA and mRNA profiles reveals potential lncRNA functions during early HIV infection. PMID:33794921
Study of Genome-Wide Occupancy of Long Non-Coding RNAs Using Chromatin Isolation by RNA Purification (ChIRP). PMID:33792876
Long non-coding RNAs (LncRNAs), viral oncogenomics, and aberrant splicing events: therapeutics implications. PMID:33791160
Potential of long non-coding RNAs as a therapeutic target and molecular markers in glioblastoma pathogenesis. PMID:33786397
Research Progress and Application Prospects of Long Noncoding RNAs in Gastric Neoplasms. PMID:33769145
Long Non-Coding RNAs: Role in Testicular Cancers. PMID:33767982
ceRNA Network Analysis Shows That lncRNA CRNDE Promotes Progression of Glioblastoma Through Sponge mir-9-5p. PMID:33767729
Transcriptomics of Meiosis in the Male Mouse. PMID:33748111
Classifying gastric cancer using FLORA reveals clinically relevant molecular subtypes and highlights LINC01614 as a biomarker for patient prognosis. PMID:33742127
So alike yet so different. Differential expression of the long non-coding RNAs NORAD and HCG11 in breast cancer subtypes. PMID:33739352
Identification of m6A-Associated RNA Binding Proteins Using an Integrative Computational Framework. PMID:33732286
Mutant non-coding RNA resource in mouse embryonic stem cells. PMID:33729986
Multifaceted Roles of Long Non-coding RNAs in Head and Neck Cancer. PMID:33725348
The Emerging Landscape of Long Non-Coding RNAs in Colorectal Cancer Metastasis. PMID:33718238
Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-κB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains. PMID:33717069
Identification of Natural Antisense Transcripts in Mouse Brain and Their Association With Autism Spectrum Disorder Risk Genes. PMID:33716665
Effect of rs67085638 in long non-coding RNA (CCAT1) on colon cancer chemoresistance to paclitaxel through modulating the microRNA-24-3p and FSCN1. PMID:33709519
Epigenetic regulation of cellular functions in wound healing. PMID:33690920
Localization of RNAs in the nucleus: cis- and trans- regulation. PMID:33682620
The Role of LncRNAs in Translation. PMID:33672592
Filtering the Junk: Assigning Function to the Mosquito Non-Coding Genome. PMID:33671692
Novel lncRNA LINC00941 Promotes Proliferation and Invasion of Colon Cancer Through Activation of MYC. PMID:33654409
A potential association of RNF219-AS1 with ADHD: Evidence from categorical analysis of clinical phenotypes and from quantitative exploration of executive function and white matter microstructure endophenotypes. PMID:33644999
Long Non-Coding RNAs as Key Modulators of Pancreatic β-Cell Mass and Function. PMID:33628198
Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer. PMID:33622275
Mutation of a major CG methylase alters genome-wide lncRNA expression in rice. PMID:33617633
Epigenetic Landscape of Liquid Biopsy in Colorectal Cancer. PMID:33614651
The Regulatory Functions of lncRNAs on Angiogenesis Following Ischemic Stroke. PMID:33613191
Targeting Human lncRNAs for Treating Cardiometabolic Diseases. PMID:33608863
Long Noncoding RNA FOXP4-AS1 Predicts Unfavourable Prognosis and Regulates Proliferation and Invasion in Hepatocellular Carcinoma. PMID:33604387
Characterization of the nuclear and cytosolic transcriptomes in human brain tissue reveals new insights into the subcellular distribution of RNA transcripts. PMID:33603054
Pineal gland transcriptomic profiling reveals the differential regulation of lncRNA and mRNA related to prolificacy in STH sheep with two FecB genotypes. PMID:33602139
Identification of a long non-coding RNA regulator of liver carcinoma cell survival. PMID:33589614
Functional Non-coding RNA During Embryonic Myogenesis and Postnatal Muscle Development and Disease. PMID:33585483
The long non-coding RNA GHSROS reprograms prostate cancer cell lines toward a more aggressive phenotype. PMID:33585078
Novel insights into the interaction between long non-coding RNAs and microRNAs in glioma. PMID:33582947
Long and short non-coding RNA and radiation response: a review. PMID:33582242
The expression of long non-coding RNAs is associated with H3Ac and H3K4me2 changes regulated by the HDA6-LDL1/2 histone modification complex in Arabidopsis. PMID:33575615
Associating divergent lncRNAs with target genes by integrating genome sequence, gene expression and chromatin accessibility data. PMID:33575579
Deep analysis of RNA N6-adenosine methylation (m6A) patterns in human cells. PMID:33575554
Conserved regions in long non-coding RNAs contain abundant translation and protein-RNA interaction signatures. PMID:33575549
Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes. PMID:33575113
LncRNAs and Immunity: Coding the Immune System with Noncoding Oligonucleotides. PMID:33572313
Long Non-coding RNA NEAT1 as an Emerging Biomarker in Breast and Gynecologic Cancers: a Systematic Overview. PMID:33569749
Role of Transposable Elements in Gene Regulation in the Human Genome. PMID:33557056
Comparative mRNA and LncRNA Analysis of the Molecular Mechanisms Associated With Low Silk Production in Bombyx mori. PMID:33552120
Long Non-coding RNAs in Parkinson's Disease. PMID:33544326
Systematic analysis of purified astrocytes after SCI unveils Zeb2os function during astrogliosis. PMID:33535036
Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia. PMID:33531590
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription. PMID:33520374
Transcriptome analysis reveals the long intergenic noncoding RNAs contributed to skeletal muscle differences between Yorkshire and Tibetan pig. PMID:33514792
What do we know about the role of lncRNAs in multiple sclerosis? PMID:33510060
Inhibition of Japanese encephalitis virus proliferation by long non-coding RNA SUSAJ1 in PK-15 cells. PMID:33509198
The role of micropeptides in biology. PMID:33507325
Identification of a Five-Autophagy-Related-lncRNA Signature as a Novel Prognostic Biomarker for Hepatocellular Carcinoma. PMID:33505990
Transcriptome Analysis of lncRNA-mRNA Interactions in Chronic Atrophic Gastritis. PMID:33505433
Comprehensive Review on the Clinical Relevance of Long Non-Coding RNAs in Cutaneous Melanoma. PMID:33503876
Comprehensive analysis of ceRNA network related to lincRNA in glioblastoma and prediction of clinical prognosis. PMID:33499813
Non-coding RNAs in cardiomyocyte proliferation and cardiac regeneration: Dissecting their therapeutic values. PMID:33492768
Noncoding RNAs: modulators and modulatable players during infection-induced stress response. PMID:33491070
Genome-wide identification of Aedes albopictus long noncoding RNAs and their association with dengue and Zika virus infection. PMID:33481791
Lnc-GULP1-2:1 affects granulosa cell proliferation by regulating COL3A1 expression and localization. PMID:33472700
Long Non-Coding RNAs and Their Potential Roles in the Vector-Host-Pathogen Triad. PMID:33466803
LNCcation: lncRNA localization and function. PMID:33464299
Epigenetic and non-coding regulation of alcohol abuse and addiction. PMID:33461665
lncRNA MIR4435-2HG promoted clear cell renal cell carcinoma malignant progression via miR-513a-5p/KLF6 axis. PMID:33460239
Overexpression of a Long Non-Coding RNA BC037916 is Associated with Pancreatic Tumorigenesis and Poor Prognosis. PMID:33447050
Transcriptome-wide high-throughput mapping of protein-RNA occupancy profiles using POP-seq. PMID:33441968
Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation. PMID:33432115
Autophagy and gastrointestinal cancers: the behind the scenes role of long non-coding RNAs in initiation, progression, and treatment resistance. PMID:33432087
PVT1 signals an androgen-dependent transcriptional repression program in prostate cancer cells and a set of the repressed genes predicts high-risk tumors. PMID:33430890
LncRNA LINC00240 suppresses invasion and migration in non-small cell lung cancer by sponging miR-7-5p. PMID:33422052
Noncoding RNAs Serve as the Deadliest Universal Regulators of all Cancers. PMID:33419895
The Role of cis- and trans-Acting RNA Regulatory Elements in Leukemia. PMID:33419342
TERRA Gene Expression in Gastric Cancer: Role of hTERT. PMID:33411257
Circular RNA circGSE1 Promotes Cervical Cancer Progression Through miR-138-5p/Vimentin. PMID:33408484
Interplay between host non-coding RNAs and influenza viruses. PMID:33404285
A chromatin-associated splicing isoform of OIP5-AS1 acts in cis to regulate the OIP5 oncogene. PMID:33404283
On the functional relevance of spatiotemporally-specific patterns of experience-dependent long noncoding RNA expression in the brain. PMID:33397182
Circulating Non-Coding RNAs in Head and Neck Cancer: Roles in Diagnosis, Prognosis, and Therapy Monitoring. PMID:33396240
lnc-RHL, a novel long non-coding RNA required for the differentiation of hepatocytes from human bipotent progenitor cells. PMID:33393114
Long Non-Coding RNAs: The Regulatory Mechanisms, Research Strategies, and Future Directions in Cancers. PMID:33392092
Identification of mRNAs and lncRNAs Involved in the Regulation of Follicle Development in Goat. PMID:33391342
LncRNA XIST acts as a MicroRNA-520 sponge to regulate the Cisplatin resistance in NSCLC cells by mediating BAX through CeRNA network. PMID:33390811
Downregulation of lncRNA TSLNC8 promotes melanoma resistance to BRAF inhibitor PLX4720 through binding with PP1α to re-activate MAPK signaling. PMID:33389075
Functioning of Long Noncoding RNAs Expressed in Macrophage in the Development of Atherosclerosis. PMID:33381026
Tissue-selective alternate promoters guide NLRP6 expression. PMID:33376129
Long Non-Coding RNAs, the Dark Matter: An Emerging Regulatory Component in Plants. PMID:33374835
Gene regulation by long non-coding RNAs and its biological functions. PMID:33353982
MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression. PMID:33353933
Emerging Role and Therapeutic Potential of lncRNAs in Colorectal Cancer. PMID:33352769
The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis. PMID:33339309
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1. PMID:33335798
The PARP Inhibitor Olaparib Modulates the Transcriptional Regulatory Networks of Long Non-Coding RNAs during Vasculogenic Mimicry. PMID:33333852
Novel Genetic and Epigenetic Biomarkers of Prognostic and Predictive Significance in Stage II/III Colorectal Cancer. PMID:33333293
Emerging Role of Long Noncoding RNAs in Perioperative Neurocognitive Disorders and Anesthetic-Induced Developmental Neurotoxicity. PMID:33332892
Biomarkers for Heart Failure Prognosis: Proteins, Genetic Scores and Non-coding RNAs. PMID:33330662
Down-Regulation of Lnc-CYP7A1-1 Rejuvenates Aged Human Mesenchymal Stem Cells to Improve Their Efficacy for Heart Repair Through SYNE1. PMID:33330489
Evolution of Genome-Organizing Long Non-coding RNAs in Metazoans. PMID:33329735
Drug Response Associated With and Prognostic lncRNAs Mediated by DNA Methylation and Transcription Factors in Colon Cancer. PMID:33329694
Disease-Causing Mutations and Rearrangements in Long Non-coding RNA Gene Loci. PMID:33329688
A Prognostic Model Based on Immune-Related Long Non-Coding RNAs for Patients With Cervical Cancer. PMID:33328990
Annotation of Full-Length Long Noncoding RNAs with Capture Long-Read Sequencing (CLS). PMID:33326074
Classification of Long Noncoding RNAs by k-mer Content. PMID:33326069
Identifying cortical specific long noncoding RNAs modified by m6A RNA methylation in mouse brains. PMID:33323036
High-quality chromosome-level genome assembly and full-length transcriptome analysis of the pharaoh ant Monomorium pharaonis. PMID:33319913
Functional interaction between long non-coding RNA and microRNA in rheumatoid arthritis. PMID:33319382
Genome-wide correlation analysis to identify amplitude regulators of circadian transcriptome output. PMID:33318596
Functional Screening Techniques to Identify Long Non-Coding RNAs as Therapeutic Targets in Cancer. PMID:33317042
Systematic evaluation, verification and comparison of tuberculosis-related non-coding RNA diagnostic panels. PMID:33314695
The long non-coding RNA landscape in triple-negative breast cancer. PMID:33314471
The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans. PMID:33311506
Identification of Functional Genes in Pterygium Based on Bioinformatics Analysis. PMID:33299863
Long non-coding RNA levels can be modulated by 5-azacytidine in Schistosoma mansoni. PMID:33299037
lncRNAs in T lymphocytes: RNA regulation at the heart of the immune response. PMID:33296288
Our emerging understanding of the roles of long non-coding RNAs in normal liver function, disease, and malignancy. PMID:33294829
A long noncoding RNA, LncMyoD, modulates chromatin accessibility to regulate muscle stem cell myogenic lineage progression. PMID:33293420
Deep Learning in LncRNAome: Contribution, Challenges, and Perspectives. PMID:33266128
Identification of a De Novo Xq26.2 Microduplication Encompassing FIRRE Gene in a Child with Intellectual Disability. PMID:33255855
NAIL: an evolutionarily conserved lncRNA essential for licensing coordinated activation of p38 and NFκB in colitis. PMID:33239342
An integrative atlas of chicken long non-coding genes and their annotations across 25 tissues. PMID:33235280
The long non-coding RNA TSLC8 inhibits colorectal cancer by stabilizing puma. PMID:33218295
The Role of Extracellular Vesicles (EVs) in the Epigenetic Regulation of Bone Metabolism and Osteoporosis. PMID:33213099
LINC00473 as an Immediate Early Gene under the Control of the EGR1 Transcription Factor. PMID:33198374
Tumor Suppressor LINC02487 Inhibits Oral Squamous Cell Carcinoma Cell Migration and Invasion Through the USP17-SNAI1 Axis. PMID:33194625
Individualized Prediction of Survival by a 10-Long Non-coding RNA-Based Prognostic Model for Patients With Breast Cancer. PMID:33194577
The lncRNA MALAT1/miR-30/Spastin Axis Regulates Hippocampal Neurite Outgrowth. PMID:33192306
Emerging Roles of Long Noncoding RNAs in the Cytoplasmic Milieu. PMID:33182489
Plant Non-Coding RNAs: Origin, Biogenesis, Mode of Action and Their Roles in Abiotic Stress. PMID:33182372
Upregulated lnc‑HRK‑2:1 prompts nucleus pulposus cell senescence in intervertebral disc degeneration. PMID:33174041
The Diagnostic and Prognostic Value of Serum lncRNA NEAT1 in Colorectal Cancer. PMID:33173332
Non-Coding RNAs as Sensors of Oxidative Stress in Neurodegenerative Diseases. PMID:33171576
The Role of Circular RNAs in Pancreatic Ductal Adenocarcinoma and Biliary-Tract Cancers. PMID:33158116
Aberrantly upregulated FAM83H-AS1 facilitates malignant progression of esophageal squamous cell carcinoma. PMID:33154766
The role of lncRNAs in innate immunity and inflammation. PMID:33138685
MicroRNAs and lncRNAs-A New Layer of Myeloid-Derived Suppressor Cells Regulation. PMID:33133086
Autoregulation of JARID2 through PRC2 interaction with its antisense ncRNA. PMID:33126912
Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility. PMID:33126901
Roles of Non-Coding RNAs on Anaplastic Thyroid Carcinomas. PMID:33126409
lncRNA KTN1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑505‑3p. PMID:33125151
Long Noncoding RNA CDKN2B-AS1 Facilitates Lung Cancer Development Through Regulating miR-378b/NR2C2. PMID:33116641
New Insights on the Mobility of Viral and Host Non-Coding RNAs Reveal Extracellular Vesicles as Intriguing Candidate Antiviral Targets. PMID:33114356
Immune-related miRNA signature identifies prognosis and immune landscape in head and neck squamous cell carcinomas. PMID:33111959
High-throughput analysis and functional interpretation of extracellular vesicle content in hematological malignancies. PMID:33101605
Non-Coding RNAs in Psychiatric Disorders and Suicidal Behavior. PMID:33101077
Long non-coding RNAs in plants: emerging modulators of gene activity in development and stress responses. PMID:33099688
Interferon-Mediated Long Non-Coding RNA Response in Macrophages in the Context of HIV. PMID:33086748
The Role of lncRNA TUG1 in the Parkinson Disease and Its Effect on Microglial Inflammatory Response. PMID:33085068
Genome-wide analysis of differentially expressed mRNAs, lncRNAs, and circRNAs in chicken bursae of Fabricius during infection with very virulent infectious bursal disease virus. PMID:33076825
Exosome-Derived LncRNAs in Lung Cancer. PMID:33072553
Identification and characterization of functional long noncoding RNAs in cancer. PMID:33058262
LINC00885 a Novel Oncogenic Long Non-Coding RNA Associated with Early Stage Breast Cancer Progression. PMID:33049922
LncRNA Platr22 promotes super-enhancer activity and stem cell pluripotency. PMID:33049031
Mechanism of efficient double-strand break repair by a long non-coding RNA. PMID:33045735
The regulatory roles of long noncoding RNAs in osteoporosis. PMID:33042467
NCBP3: A Multifaceted Adaptive Regulator of Gene Expression. PMID:33032857
eRNAs and Superenhancer lncRNAs Are Functional in Human Prostate Cancer. PMID:33029258
Autophagy-Associated lncRNAs: Promising Targets for Neurological Disease Diagnosis and Therapy. PMID:33029125
lncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA. PMID:33020484
Target Enrichment Enables the Discovery of lncRNAs with Somatic Mutations or Altered Expression in Paraffin-Embedded Colorectal Cancer Samples. PMID:33019720
ERG-Associated lncRNA (ERGAL) Promotes the Stability and Integrity of Vascular Endothelial Barrier During Dengue Viral Infection via Interaction With miR-183-5p. PMID:33014896
Long non-coding RNAs in prostate tumorigenesis and therapy (Review). PMID:33005410
Retinoblastoma Tumor Suppressor Protein Roles in Epigenetic Regulation. PMID:33003565
Non-coding RNAs in Brain Tumors, the Contribution of lncRNAs, circRNAs, and snoRNAs to Cancer Development-Their Diagnostic and Therapeutic Potential. PMID:32977537
FuncPEP: A Database of Functional Peptides Encoded by Non-Coding RNAs. PMID:32977531
LncRNA Profiling Reveals That the Deregulation of H19, WT1-AS, TCL6, and LEF1-AS1 Is Associated with Higher-Risk Myelodysplastic Syndrome. PMID:32977510
Long Non-Coding RNA Profile Study Identifies an Immune-Related lncRNA Prognostic Signature for Kidney Renal Clear Cell Carcinoma. PMID:32974157
Interpreting the impact of noncoding structural variation in neurodevelopmental disorders. PMID:32973355
Long non-coding RNAs in motor neuron development and disease. PMID:32970857
Regulation of neuronal commitment in mouse embryonic stem cells by the Reno1/Bahcc1 locus. PMID:32969152
The Interplay between Long Noncoding RNAs and Proteins of the Epigenetic Machinery in Ovarian Cancer. PMID:32967233
Extracellular Vesicle-Mediated Vascular Cell Communications in Hypertension: Mechanism Insights and Therapeutic Potential of ncRNAs. PMID:32964302
LINC00511 promotes lung squamous cell carcinoma proliferation and migration via inhibiting miR-150-5p and activating TADA1. PMID:32953492
Limitations of Detecting Genetic Variants from the RNA Sequencing Data in Tissue and Fine-Needle Aspiration Samples. PMID:32948110
Liquid lncRNA Biopsy for the Evaluation of Locally Advanced and Metastatic Squamous Cell Carcinomas of the Head and Neck. PMID:32947877
Characterization of Long Non-coding RNA Signatures of Intracranial Aneurysm in Circulating Whole Blood. PMID:32939739
The roles of long noncoding RNAs in breast cancer metastasis. PMID:32929060
Natural antisense transcripts in the biological hallmarks of cancer: powerful regulators hidden in the dark. PMID:32928281
Non-Coding RNAs: Strategy for Viruses' Offensive. PMID:32927786
Expression profile of lncRNAs and mRNAs in intestinal macrophages. PMID:32901859
Radiation induces dynamic changes to the T cell repertoire in renal cell carcinoma patients. PMID:32900949
Noncoding RNAs and Midbrain DA Neurons: Novel Molecular Mechanisms and Therapeutic Targets in Health and Disease. PMID:32899172
A long non-coding RNA (Lrap) modulates brain gene expression and levels of alcohol consumption in rats. PMID:32893479
A long non-coding RNA GATA6-AS1 adjacent to GATA6 is required for cardiomyocyte differentiation from human pluripotent stem cells. PMID:32888237
Genome-wide association study identifies candidate markers related to lincRNAs associated with male infertility in the Greek population. PMID:32880781
Pooled analysis of radiation hybrids identifies loci for growth and drug action in mammalian cells. PMID:32878976
Growth retardation-responsive analysis of mRNAs and long noncoding RNAs in the liver tissue of Leiqiong cattle. PMID:32868811
Genome-wide analysis of long non-coding RNAs in adult tissues of the melon fly, Zeugodacus cucurbitae (Coquillett). PMID:32867696
Long Non-coding RNA Derived from lncRNA-mRNA Co-expression Networks Modulates the Locust Phase Change. PMID:32866667
An integrative proteogenomics approach reveals peptides encoded by annotated lincRNA in the mouse kidney inner medulla. PMID:32866085
Aberrant allelic-switch of antisense lncRNA IRAIN may be an early diagnostic marker in laryngeal cancer. PMID:32863898
Long non-coding RNA CASC7 is associated with the pathogenesis of heart failure via modulating the expression of miR-30c. PMID:32860492
Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion. PMID:32858747
The Effect of LINC01296 Expression in Patients with Cancer: A Systematic Review and Meta-Analysis. PMID:32856843
Back to the Future: Rethinking the Great Potential of lncRNAS for Optimizing Chemotherapeutic Response in Ovarian Cancer. PMID:32854207
Genome-Wide Transcriptional Regulation of the Long Non-coding RNA Steroid Receptor RNA Activator in Human Erythroblasts. PMID:32849830
Integrated Dissection of lncRNA-Perturbated Triplets Reveals Novel Prognostic Signatures Across Cancer Types. PMID:32846981
Global identification of a marine diatom long noncoding natural antisense transcripts (NATs) and their response to phosphate fluctuations. PMID:32839470
Methods for the Study of Long Noncoding RNA in Cancer Cell Signaling. PMID:32813246
Correlation analysis between CARMEN variants and alcohol-induced osteonecrosis of the femoral head in the Chinese population. PMID:32799824
Identification of DGUOK-AS1 as a Prognostic Factor in Breast Cancer by Bioinformatics Analysis. PMID:32766141
Epigenomic Dysregulation in Schizophrenia: In Search of Disease Etiology and Biomarkers. PMID:32764320
Long noncoding RNA functionality in imprinted domain regulation. PMID:32760061
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN. PMID:32754899
A lncRNA landscape in breast cancer reveals a potential role for AC009283.1 in proliferation and apoptosis in HER2-enriched subtype. PMID:32753692
Long Non-Coding RNAs in Atrial Fibrillation: Pluripotent Stem Cell-Derived Cardiomyocytes as a Model System. PMID:32751460
Involvement of long noncoding RNAs in the pathogenesis of autoimmune diseases. PMID:32743525
LncZEB1-AS1 regulates hepatocellular carcinoma bone metastasis via regulation of the miR-302b-EGFR-PI3K-AKT axis. PMID:32742459
Role of non-coding-RNAs in response to environmental stressors and consequences on human health. PMID:32723695
lncRNA_Mdeep: An Alignment-Free Predictor for Distinguishing Long Non-Coding RNAs from Protein-Coding Transcripts by Multimodal Deep Learning. PMID:32718000
Altered Long Noncoding RNA Expression Profile in Multiple Myeloma Patients with Bisphosphonate-Induced Osteonecrosis of the Jaw. PMID:32714991
SNPs in lncRNA Regions and Breast Cancer Risk. PMID:32714364
PRIME-3D2D is a 3D2D model to predict binding sites of protein-RNA interaction. PMID:32678300
Coding of Glioblastoma Progression and Therapy Resistance through Long Noncoding RNAs. PMID:32650527
lncRNA IGKJ2-MALLP2 suppresses LSCC proliferation, migration, invasion, and angiogenesis by sponging miR-1911-3p/p21. PMID:32639636
Epigenetic alterations in Sjögren's syndrome patient saliva. PMID:32639584
CARMAL Is a Long Non-coding RNA Locus That Regulates MFGE8 Expression. PMID:32625236
The Contribution of lincRNAs at the Interface between Cell Cycle Regulation and Cell State Maintenance. PMID:32619701
Long Non-coding RNA and mRNA Profile of Liver Tissue During Four Developmental Stages in the Chicken. PMID:32612636
Immune-related long non-coding RNA signature identified prognosis and immunotherapeutic efficiency in bladder cancer (BLCA). PMID:32607061
Insights into lncRNAs in Alzheimer's disease mechanisms. PMID:32605500
Five-lncRNA signature in plasma exosomes serves as diagnostic biomarker for esophageal squamous cell carcinoma. PMID:32597791
High-Throughput Sequencing and Exploration of the lncRNA-circRNA-miRNA-mRNA Network in Type 2 Diabetes Mellitus. PMID:32596376
Identification of a Seven-lncRNA Immune Risk Signature and Construction of a Predictive Nomogram for Lung Adenocarcinoma. PMID:32596372
Exploring the Role of Non-Coding RNAs in the Pathophysiology of Systemic Lupus Erythematosus. PMID:32580306
Long Noncoding RNA HOTTIP Serves as an Independent Predictive Biomarker for the Prognosis of Patients with Clear Cell Renal Cell Carcinoma. PMID:32566641
The lncRNA RP11-142A22.4 promotes adipogenesis by sponging miR-587 to modulate Wnt5β expression. PMID:32561739
FOXO3a-mediated long non-coding RNA LINC00261 resists cardiomyocyte hypoxia/reoxygenation injury via targeting miR23b-3p/NRF2 axis. PMID:32558131
Long Noncoding RNAs in Diffuse Large B-Cell Lymphoma: Current Advances and Perspectives. PMID:32547063
Yeast Telomerase RNA Flexibly Scaffolds Protein Subunits: Results and Repercussions. PMID:32545864
Roles of lncRNAs in influenza virus infection. PMID:32543285
LncRNA and mRNA expression profiles reveal the potential roles of lncRNA contributing to regulating dural penetration in clival chordoma. PMID:32533822
Significance of Single-Nucleotide Variants in Long Intergenic Non-protein Coding RNAs. PMID:32523949
New twists on long noncoding RNAs: from mobile elements to motile cancer cells. PMID:32522127
The functions of long non-coding RNAs in neural stem cell proliferation and differentiation. PMID:32514332
A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation. PMID:32513690
Epigenetic Regulation of Kaposi's Sarcoma-Associated Herpesvirus Latency. PMID:32508765
Epigenomics-based identification of oestrogen-regulated long noncoding RNAs in ER+ breast cancer. PMID:32506995
Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus. PMID:32504554
Long non-coding RNAs in ovarian granulosa cells. PMID:32503679
Challenges and Strategies in Ascribing Functions to Long Noncoding RNAs. PMID:32503290
MALAT1 Long Non-Coding RNA: Functional Implications. PMID:32503170
GC-AG Introns Features in Long Non-coding and Protein-Coding Genes Suggest Their Role in Gene Expression Regulation. PMID:32499820
The Long and Short of It: The Emerging Roles of Non-Coding RNA in Small Extracellular Vesicles. PMID:32498257
Fusions involving BCOR and CREBBP are rare events in infiltrating glioma. PMID:32493417
Implications of Long Non-Coding RNAs in Age-Altered Proteostasis. PMID:32489713
LncRNA MEG3 suppressed the progression of ovarian cancer via sponging miR-30e-3p and regulating LAMA4 expression. PMID:32489317
The New Frontier of Functional Genomics: From Chromatin Architecture and Noncoding RNAs to Therapeutic Targets. PMID:32486876
Long Noncoding RNAs Involved in the Endocrine Therapy Resistance of Breast Cancer. PMID:32486413
Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1. PMID:32467232
Long non-coding RNAs in cutaneous biology and keratinocyte carcinomas. PMID:32462404
An evolutionarily conserved RNA structure in the functional core of the lincRNA Cyrano. PMID:32457084
SNHG16/miR-605-3p/TRAF6/NF-κB feedback loop regulates hepatocellular carcinoma metastasis. PMID:32436333
Non-coding RNAs in Nervous System Development and Disease. PMID:32435641
Emerging roles of long non-coding RNAs in the p53 network. PMID:32432959
Beyond MicroRNAs: Emerging Role of Other Non-Coding RNAs in HPV-Driven Cancers. PMID:32429207
AnnoLnc2: the one-stop portal to systematically annotate novel lncRNAs for human and mouse. PMID:32406920
Cortical cellular diversity and development in schizophrenia. PMID:32404946
Landscape of the Noncoding Transcriptome Response of Two Arabidopsis Ecotypes to Phosphate Starvation. PMID:32404413
Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells. PMID:32398033
Cluster correlation based method for lncRNA-disease association prediction. PMID:32393162
LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis. PMID:32384893
Identification and Annotation of Potential Function of Regulatory Antisense Long Non-Coding RNAs Related to Feed Efficiency in Bos taurus Bulls. PMID:32384694
Elevated Expression of the Long Noncoding RNA IFNG-AS1 in the Peripheral Blood from Patients with Rheumatoid Arthritis. PMID:32377535
The novel long noncoding RNA lncRNA-Adi regulates adipogenesis. PMID:32356938
Temporal transcriptome analysis of neuronal commitment reveals the preeminent role of the divergent lncRNA biotype and a critical candidate gene during differentiation. PMID:32351715
The long non-coding RNA MIAT/miR-139-5p/MMP2 axis regulates cell migration and invasion in non-small-cell lung cancer. PMID:32345777
Psychiatric Disorders and lncRNAs: A Synaptic Match. PMID:32344798
RNA-Binding Proteins as Important Regulators of Long Non-Coding RNAs in Cancer. PMID:32340118
A rare genomic duplication in 2p14 underlies autosomal dominant hearing loss DFNA58. PMID:32337552
Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis. PMID:32332873
LncRNA KCNQ1OT1 sponges miR-34c-5p to promote osteosarcoma growth via ALDOA enhanced aerobic glycolysis. PMID:32332718
Long Non-Coding RNAs in Biliary Tract Cancer-An Up-to-Date Review. PMID:32331331
Impaired expression of the COSMOC/MOCOS gene unit in ASD patient stem cells. PMID:32327736
The Role of Long Noncoding RNAs in Human Papillomavirus-associated Pathogenesis. PMID:32326624
LncRNAs Act as a Link between Chronic Liver Disease and Hepatocellular Carcinoma. PMID:32326098
LMSM: A modular approach for identifying lncRNA related miRNA sponge modules in breast cancer. PMID:32324747
Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation. PMID:32321486
Overexpression of LINC00160 predicts poor outcome and promotes progression of clear cell renal cell carcinoma. PMID:32315986
Identification of Long Noncoding RNA by In Situ Hybridization Approaches. PMID:32314217
Evaluation of C5orf66-AS1 as a Potential Biomarker for Predicting Early Gastric Cancer and Its Role in Gastric Carcinogenesis. PMID:32308414
Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression. PMID:32304628
The role of long noncoding RNAs in hepatocellular carcinoma. PMID:32295598
Clinical Value of lncRNA MEG3 in High-Grade Serous Ovarian Cancer. PMID:32295169
Potential Roles of Long Noncoding RNAs as Therapeutic Targets in Renal Fibrosis. PMID:32295041
LncRNA regulates tomato fruit cracking by coordinating gene expression via a hormone-redox-cell wall network. PMID:32293294
Reverse-genetics studies of lncRNAs-what we have learnt and paths forward. PMID:32290841
The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA. PMID:32284404
Emerging Roles and Potential Applications of Non-Coding RNAs in Glioblastoma. PMID:32283739
Thymosin beta-4x LINCs SPAAR to its non-coding function. PMID:32282872
MicroRNAs and long non-coding RNAs as novel regulators of ribosome biogenesis. PMID:32267487
LncRNA FOXP4-AS1 Is Involved in Cervical Cancer Progression via Regulating miR-136-5p/CBX4 Axis. PMID:32256085
Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway. PMID:32241891
U1 snRNP regulates chromatin retention of noncoding RNAs. PMID:32238924
The biological implications of Yin Yang 1 in the hallmarks of cancer. PMID:32226547
Long Non-coding RNA in Plants in the Era of Reference Sequences. PMID:32226437
Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells. PMID:32222775
A genome-wide identification, characterization and functional analysis of salt-related long non-coding RNAs in non-model plant Pistacia vera L. using transcriptome high throughput sequencing. PMID:32221354
Knockdown of long non-coding RNA prostate cancer-associated transcript 1 inhibits the proliferation and metastasis of tongue squamous cell carcinoma cells by upregulating p21. PMID:32218838
Analysis of Long Noncoding RNA and mRNA Expression Profiles of Testes with High and Low Sperm Motility in Domestic Pigeons (Columba livia). PMID:32218174
Gastric Cancer MicroRNAs Meta-signature. PMID:32215261
Quantifying RNA Editing in Deep Transcriptome Datasets. PMID:32211029
LncRNA H19 gene rs2839698 polymorphism is associated with a decreased risk of colorectal cancer in a Chinese Han population: A case-control study. PMID:32207861
Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway. PMID:32202492
Interactions Among Non-Coding RNAs in Diabetic Nephropathy. PMID:32194418
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells. PMID:32189969
NORFA, long intergenic noncoding RNA, maintains sow fertility by inhibiting granulosa cell death. PMID:32188888
Molecular mechanisms underlying actions of certain long noncoding RNAs in Alzheimer's disease. PMID:32185592
Long Noncoding RNA LINC00460 Promotes Hepatocellular Carcinoma Progression via Regulation of miR-342-3p/AGR2 Axis. PMID:32184630
Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets. PMID:32183241
ncRNAs: New Players in Mitochondrial Health and Disease? PMID:32180794
Whole transcriptome expression profiles in placenta samples from women with gestational diabetes mellitus. PMID:32174045
Update on SLC6A14 in lung and gastrointestinal physiology and physiopathology: focus on cystic fibrosis. PMID:32166393
Beyond classic editing: innovative CRISPR approaches for functional studies of long non-coding RNA. PMID:32161809
Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation. PMID:32160538
The novel long noncoding RNA CRART16 confers cetuximab resistance in colorectal cancer cells by enhancing ERBB3 expression via miR-371a-5p. PMID:32158358
Transcriptomic Analyses for Identification and Prioritization of Genes Associated With Alzheimer's Disease in Humans. PMID:32154224
A Long Non-coding RNA IVRPIE Promotes Host Antiviral Immune Responses Through Regulating Interferon β1 and ISG Expression. PMID:32153544
Identification of Three lncRNAs as Potential Predictive Biomarkers of Lung Adenocarcinoma. PMID:32149133
Identification and validation of potential key long noncoding RNAs in sorafenib-resistant hepatocellular carcinoma cells. PMID:32149026
Transcriptome Analysis Reveals Long Intergenic Non-Coding RNAs Contributed to Intramuscular Fat Content Differences between Yorkshire and Wei Pigs. PMID:32138348
Long non-coding RNA FENDRR inhibits migration and invasion of cutaneous malignant melanoma cells. PMID:32134466
Whole Transcriptome Analysis of Mesenchyme Tissue in Sika Deer Antler Revealed the CeRNAs Regulatory Network Associated With Antler Development. PMID:32133026
LncRNAs in molluscan and mammalian stages of parasitic schistosomes are developmentally-regulated and coordinately expressed with protein-coding genes. PMID:32131676
Regulation of myosin heavy chain antisense long noncoding RNA in human vastus lateralis in response to exercise training. PMID:32130073
The role of long non-coding RNAs in mediating chemoresistance by modulating autophagy in cancer. PMID:32129701
Long noncoding RNAs: new insights in modulating mammalian spermatogenesis. PMID:32128162
MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer. PMID:32127004
LincRNA-EPS in biomimetic vesicles targeting cerebral infarction promotes inflammatory resolution and neurogenesis. PMID:32122362
Role of non-coding RNAs and RNA modifiers in cancer therapy resistance. PMID:32122355
A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma. PMID:32108138
Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells. PMID:32106863
LncRNAs as Potential Therapeutic Targets in Thyroid Cancer. PMID:32102500
Long non-coding RNAs in development and disease: conservation to mechanisms. PMID:32100288
Comprehensive analysis of long non-coding RNAs and mRNAs in skeletal muscle of diabetic Goto-Kakizaki rats during the early stage of type 2 diabetes. PMID:32095365
RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions. PMID:32094342
Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease. PMID:32093746
Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers. PMID:32081859
Analysis of Long Non-Coding RNAs and mRNAs Associated with Lactation in the Crop of Pigeons (Columba livia). PMID:32079139
LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway. PMID:32077915
MEG3 Promotes Differentiation of Porcine Satellite Cells by Sponging miR-423-5p to Relieve Inhibiting Effect on SRF. PMID:32075310
Functional characterization of long noncoding RNAs. PMID:32068613
Genome-wide analyses reveal the role of noncoding variation in complex traits during rice domestication. PMID:32064312
Comprehensive Genomic Characterization Analysis of lncRNAs in Cells With Porcine Delta Coronavirus Infection. PMID:32063887
LncRNA XIST modulates HIF-1A/AXL signaling pathway by inhibiting miR-93-5p in colorectal cancer. PMID:32061057
Long non-coding RNAs in immune regulation and their potential as therapeutic targets. PMID:32058929
Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis. PMID:32050897
Nucleosome destabilization by nuclear non-coding RNAs. PMID:32047236
A nomogram combining long non-coding RNA expression profiles and clinical factors predicts survival in patients with bladder cancer. PMID:32047140
Genome-wide identification and characterization of novel long non-coding RNA in Ruminal tissue affected with sub-acute Ruminal acidosis from Holstein cattle. PMID:32043213
Re-recognition of pseudogenes: From molecular to clinical applications. PMID:32042317
Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq. PMID:32040509
Long Non-coding RNAs Involved in Resistance to Chemotherapy in Ovarian Cancer. PMID:32039022
Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1. PMID:32037441
Non-Coding RNAs as Regulators and Markers for Targeting of Breast Cancer and Cancer Stem Cells. PMID:32033146
Altered Expression of Long Noncoding and Messenger RNAs in Diabetic Nephropathy following Treatment with Rosiglitazone. PMID:32025515
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis. PMID:32024996
Development of a long non-coding RNA signature for prediction of response to neoadjuvant chemoradiotherapy in locally advanced rectal adenocarcinoma. PMID:32023246
Progress in understanding the relationship between long noncoding RNA and endometriosis. PMID:32021971
Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. PMID:32020063
Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA. PMID:32019587
MicroRNA and Cardiovascular Diseases. PMID:32018347
HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion. PMID:32010621
Drug Resistance Biomarkers and Their Clinical Applications in Childhood Acute Lymphoblastic Leukemia. PMID:32010613
The Emerging Role of Noncoding RNAs in Pediatric Inflammatory Bowel Disease. PMID:32009179
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. PMID:32005828
lncRNA CISAL Inhibits BRCA1 Transcription by Forming a Tertiary Structure at Its Promoter. PMID:32000125
Emerging role of long non-coding RNAs in cancer precision medicine. PMID:31993497
Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3. PMID:31956895
A Novel Approach to Identify Enhancer lincRNAs by Integrating Genome, Epigenome, and Regulatome. PMID:31956652
Upregulation of BCAM and its sense lncRNA BAN are associated with gastric cancer metastasis and poor prognosis. PMID:31951095
High-throughput sequencing analysis of lncRNAs in hippocampus tissues with hypoxic-ischemic brain damage. PMID:31949607
Unraveling the epigenetic landscape of depression: focus on early life stress . PMID:31949402
The Missing "lnc" between Genetics and Cardiac Disease. PMID:31947625
Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination. PMID:31924448
Integrated analysis of a ceRNA network reveals potential prognostic lncRNAs in gastric cancer. PMID:31923354
MAGI2 Gene Region and Celiac Disease. PMID:31921880
Non-coding RNAs underlie genetic predisposition to breast cancer. PMID:31910864
When Long Noncoding Becomes Protein Coding. PMID:31907280
MicroRNAs: Biological Regulators in Pathogen-Host Interactions. PMID:31906500
Genome-wide interaction target profiling reveals a novel Peblr20-eRNA activation pathway to control stem cell pluripotency. PMID:31903125
HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis. PMID:31900259
Polymorphisms in the PVT1 Gene and Susceptibility to the Lung Cancer in a Chinese Northeast Population: a Case-control Study. PMID:31897242
A Long Non-coding RNA Lnc712 Regulates Breast Cancer Cell Proliferation. PMID:31892853
Multi-species annotation of transcriptome and chromatin structure in domesticated animals. PMID:31884969
Transcriptome alteration spectrum in rat lung induced by radiotherapy. PMID:31873113
Revealing stage-specific expression patterns of long noncoding RNAs along mouse spermatogenesis. PMID:31869276
The stem cell-specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A-rearranged leukemia. PMID:31867596
Prognostic and Clinicopathological Significance of Long Non-coding RNA PANDAR Expression in Cancer Patients: A Meta-Analysis. PMID:31850222
A New Era of Prostate Cancer Precision Medicine. PMID:31850193
Noncoding RNAs in inflammation and colorectal cancer. PMID:31847691
Comparative analyses of long non-coding RNA profiles in vivo in cystic fibrosis lung airway and parenchyma tissues. PMID:31842871
Long Noncoding RNA (lncRNA) FOXD2-AS1 Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Regulating MiR-185/AKT Axis. PMID:31841454
Epigenetic mechanisms of neurodegenerative diseases and acute brain injury. PMID:31838024
A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome. PMID:31836654
Are Long Noncoding RNAs New Potential Biomarkers in Gastrointestinal Stromal Tumors (GISTs)? The Role of H19 and MALAT1. PMID:31827510
Biological Network Approach for the Identification of Regulatory Long Non-Coding RNAs Associated With Metabolic Efficiency in Cattle. PMID:31824560
A novel long noncoding RNA Linc-ASEN represses cellular senescence through multileveled reduction of p21 expression. PMID:31819156
Benchmark of long non-coding RNA quantification for RNA sequencing of cancer samples. PMID:31808800
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis. PMID:31804951
The MS-lincRNA landscape reveals a novel lincRNA BCLIN25 that contributes to tumorigenesis by upregulating ERBB2 expression via epigenetic modification and RNA-RNA interactions in breast cancer. PMID:31801944
Approaches for Understanding the Mechanisms of Long Noncoding RNA Regulation of Gene Expression. PMID:31791999
Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs. PMID:31784461
Long Non-coding RNA PVT1 as a Prognostic and Therapeutic Target in Pediatric Cancer. PMID:31781490
Global Analysis of Enhancer Targets Reveals Convergent Enhancer-Driven Regulatory Modules. PMID:31775028
Co-expression Network of mRNAs and lncRNAs Regulated by Stress-Linked Behavioral Assays. PMID:31760461
In-cell identification and measurement of RNA-protein interactions. PMID:31757954
LINC01149 variant modulates MICA expression that facilitates hepatitis B virus spontaneous recovery but increases hepatocellular carcinoma risk. PMID:31754211
Long noncoding RNAs in lipid metabolism: literature review and conservation analysis across species. PMID:31752679
Regulation of mTOR signaling by long non-coding RNA. PMID:31751821
Long noncoding RNAs: emerging roles in pulmonary hypertension. PMID:31741121
DIANA-LncBase v3: indexing experimentally supported miRNA targets on non-coding transcripts. PMID:31732741
Role of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models. PMID:31731549
The Role of Non-coding RNAs in Oncology. PMID:31730848
Maize transposable elements contribute to long non-coding RNAs that are regulatory hubs for abiotic stress response. PMID:31729949
Regulation of gene expression by cis-acting long non-coding RNAs. PMID:31729473
Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk. PMID:31727082
A transcriptomic profile of topping responsive non-coding RNAs in tobacco roots (Nicotiana tabacum). PMID:31726968
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis. PMID:31723143
HIV-1 Tat Interacts with a Kaposi's Sarcoma-Associated Herpesvirus Reactivation-Upregulated Antiangiogenic Long Noncoding RNA, LINC00313, and Antagonizes Its Function. PMID:31723026
Mechanisms and Functions of Long Non-Coding RNAs at Multiple Regulatory Levels. PMID:31717266
Long non-coding RNAs and latent HIV - A search for novel targets for latency reversal. PMID:31710657
The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective. PMID:31709179
Ageing-associated changes in the expression of lncRNAs in human tissues reflect a transcriptional modulation in ageing pathways. PMID:31706952
Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution. PMID:31698782
LncRNA-mediated regulation of SOX9 expression in basal subtype breast cancer cells. PMID:31690584
Enhancer LncRNAs Influence Chromatin Interactions in Different Ways. PMID:31681405
lnc9141-a and -b Play a Different Role in Bovine Myoblast Proliferation, Apoptosis, and Differentiation. PMID:31675668
The long non-coding RNA lncRNA973 is involved in cotton response to salt stress. PMID:31666019
Long Noncoding RNAs in Acute Myeloid Leukemia: Functional Characterization and Clinical Relevance. PMID:31653018
Editorial: Long Non-coding RNAs and Immunity. PMID:31649679
The TWIST1-centered competing endogenous RNA network promotes proliferation, invasion, and migration of lung adenocarcinoma. PMID:31645542
Potential and Challenges of Aptamers as Specific Carriers of Therapeutic Oligonucleotides for Precision Medicine in Cancer. PMID:31636244
Cross-Talk between Mitochondrial Dysfunction-Provoked Oxidative Stress and Aberrant Noncoding RNA Expression in the Pathogenesis and Pathophysiology of SLE. PMID:31635056
AK001058 promotes the proliferation and migration of colorectal cancer cells by regulating methylation of ADAMTS12. PMID:31632555
LINC00673 is activated by YY1 and promotes the proliferation of breast cancer cells via the miR-515-5p/MARK4/Hippo signaling pathway. PMID:31623640
De novo transcriptome of Gymnema sylvestre identified putative lncRNA and genes regulating terpenoid biosynthesis pathway. PMID:31619732
Endogenous intronic antisense long non-coding RNA, MGAT3-AS1, and kidney transplantation. PMID:31611608
The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. PMID:31607563
The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis. PMID:31605483
Linking long noncoding RNA to drug resistance. PMID:31601736
Long Non-Coding RNAs and Related Molecular Pathways in the Pathogenesis of Epilepsy. PMID:31581735
Weighted Gene Co-Expression Analyses Point to Long Non-Coding RNA Hub Genes at Different Schistosoma mansoni Life-Cycle Stages. PMID:31572441
Inferring Latent Disease-lncRNA Associations by Faster Matrix Completion on a Heterogeneous Network. PMID:31572428
The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs. PMID:31570000
LNRLMI: Linear neighbour representation for predicting lncRNA-miRNA interactions. PMID:31568653
Portrait of Tissue-Specific Coexpression Networks of Noncoding RNAs (miRNA and lncRNA) and mRNAs in Normal Tissues. PMID:31565069
Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes. PMID:31548386
Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light. PMID:31548379
Functions and Regulatory Mechanisms of lncRNAs in Skeletal Myogenesis, Muscle Disease and Meat Production. PMID:31546877
Insights into the Functions of LncRNAs in Drosophila. PMID:31546813
Long Non-Coding RNA (LncRNA) UFC1/miR-34a Contributes to Proliferation and Migration in Breast Cancer. PMID:31544897
The Growth-Arrest-Specific (GAS)-5 Long Non-Coding RNA: A Fascinating lncRNA Widely Expressed in Cancers. PMID:31533355
Comprehensive Characterization of Somatic Mutations Impacting lncRNA Expression for Pan-Cancer. PMID:31525663
Control of human testis-specific gene expression. PMID:31514204
LDAPred: A Method Based on Information Flow Propagation and a Convolutional Neural Network for the Prediction of Disease-Associated lncRNAs. PMID:31510011
Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression. PMID:31501331
ESR1-Stabilizing Long Noncoding RNA TMPO-AS1 Promotes Hormone-Refractory Breast Cancer Progression. PMID:31501276
The how and why of lncRNA function: An innate immune perspective. PMID:31487549
Roles of MYC-targeting long non-coding RNA MINCR in cell cycle regulation and apoptosis in non-small cell lung Cancer. PMID:31481083
Long Non-Coding RNA in the Pathogenesis of Cancers. PMID:31480503
CNNDLP: A Method Based on Convolutional Autoencoder and Convolutional Neural Network with Adjacent Edge Attention for Predicting lncRNA-Disease Associations. PMID:31480319
Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network. PMID:31477638
Getting the Entire Message: Progress in Isoform Sequencing. PMID:31475029
Combining next-generation sequencing and single-molecule sequencing to explore brown plant hopper responses to contrasting genotypes of japonica rice. PMID:31464583
Non-Coding RNA Regulates the Myogenesis of Skeletal Muscle Satellite Cells, Injury Repair and Diseases. PMID:31461973
Genome-Wide Identification and Characterization of Long Noncoding RNAs of Brown to White Adipose Tissue Transformation in Goats. PMID:31443273
Epigenetics of the Synapse in Neurodegeneration. PMID:31440934
The IncRNA BORG: A novel inducer of TNBC metastasis, chemoresistance, and disease recurrence. PMID:31435529
The role of long non-coding RNAs in cardiac development and disease. PMID:31435517
Conserved cell types with divergent features in human versus mouse cortex. PMID:31435019
Systematic identification and characterization of Aedes aegypti long noncoding RNAs (lncRNAs). PMID:31434910
Long non-coding RNAs and their potential functions in Ligon-lintless-1 mutant cotton during fiber development. PMID:31426741
Long non-coding RNA expressed in macrophage co-varies with the inflammatory phenotype during macrophage development and polarization. PMID:31419045
The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress. PMID:31417181
LINC00309 is associated with short disease-free survival in breast cancer. PMID:31406486
Genome-Wide Identification of Long Non-Coding RNAs and Their Regulatory Networks Involved in Apis mellifera ligustica Response to Nosema ceranae Infection. PMID:31405016
Crosstalk Between Long Non-coding RNAs, Micro-RNAs and mRNAs: Deciphering Molecular Mechanisms of Master Regulators in Cancer. PMID:31404273
Long non-coding RNA GAS5 promotes PC12 cells differentiation into Tuj1-positive neuron-like cells and induces cell cycle arrest. PMID:31397350
Non-coding RNAs in cardiovascular cell biology and atherosclerosis. PMID:31389987
Whole transcriptome analysis reveals correlation of long noncoding RNA ZEB1-AS1 with invasive profile in melanoma. PMID:31383874
Long noncoding RNA DANCR regulates proliferation and migration by epigenetically silencing FBP1 in tumorigenesis of cholangiocarcinoma. PMID:31383847
The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. PMID:31377117
Identification of a novel long non-coding RNA within RUNX1 intron 5. PMID:31366376
High-risk, Expression-Based Prognostic Long Noncoding RNA Signature in Neuroblastoma. PMID:31360848
Long noncoding RNA CCDC144NL-AS1 knockdown induces naïve-like state conversion of human pluripotent stem cells. PMID:31358062
Cell-Free Nucleic Acids and their Emerging Role in the Pathogenesis and Clinical Management of Inflammatory Bowel Disease. PMID:31357438
Data Mining by Pluralistic Approach on CRISPR Gene Editing in Plants. PMID:31354748
The novel lncRNA CALIC upregulates AXL to promote colon cancer metastasis. PMID:31353791
An expanded landscape of human long noncoding RNA. PMID:31350901
The molecular mechanism of LncRNA34a-mediated regulation of bone metastasis in hepatocellular carcinoma. PMID:31349837
Analysis of the long non-coding RNA LINC01614 in non-small cell lung cancer. PMID:31348244
Transcriptome Analysis Reveals the Effect of Long Intergenic Noncoding RNAs on Pig Muscle Growth and Fat Deposition. PMID:31341893
lncRNA expression predicts mRNA abundance. PMID:31339345
The Regulatory Roles of Long Noncoding RNAs in Acute Myeloid Leukemia. PMID:31338324
AC138128.1 an Intronic lncRNA originating from ERCC1 Implies a Potential Application in Lung Cancer Treatment. PMID:31333777
Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Peanut. PMID:31311183
Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer. PMID:31307004
Ophiopogonin-B Suppresses Epithelial-mesenchymal Transition in Human Lung Adenocarcinoma Cells via the Linc00668/miR-432-5p/EMT Axis. PMID:31281461
Glomerular expression pattern of long non-coding RNAs in the type 2 diabetes mellitus BTBR mouse model. PMID:31278342
Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling. PMID:31278255
Long Non-Coding RNAs in Kidney Disease. PMID:31277300
Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma. PMID:31273188
Improved characterization of the relationship between long intergenic non-coding RNA Linc00152 and the occurrence and development of malignancies. PMID:31270960
A conserved RNA structure is essential for a satellite RNA-mediated inhibition of helper virus accumulation. PMID:31269212
circDeep: deep learning approach for circular RNA classification from other long non-coding RNA. PMID:31268128
Stability of an RNA•DNA-DNA triple helix depends on base triplet composition and length of the RNA third strand. PMID:31265072
Discovery of a novel long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth. PMID:31253147
Overexpression of LncRNA GHET1 predicts an unfavourable survival and clinical parameters of patients in various cancers. PMID:31251476
PVT1 Signaling Is a Mediator of Cancer Progression. PMID:31249809
Developmental dynamics of lncRNAs across mammalian organs and species. PMID:31243368
Molecular Traits of Long Non-protein Coding RNAs from Diverse Plant Species Show Little Evidence of Phylogenetic Relationships. PMID:31235560
Genome-Wide Analysis of Long Non-Coding RNA Profiles in Canine Oral Melanomas. PMID:31234577
Integrated analysis of long non-coding RNA and mRNA expression in different colored skin of koi carp. PMID:31226932
RNA-protein interactions: disorder, moonlighting and junk contribute to eukaryotic complexity. PMID:31213136
Epigenetics and vascular diseases. PMID:31211956
Long non-coding RNA IQCJ-SCHIP1 antisense RNA 1 is downregulated in colorectal cancer and inhibits cell proliferation. PMID:31205916
LncRNA-Disease Association Prediction Using Two-Side Sparse Self-Representation. PMID:31191605
BarkBase: Epigenomic Annotation of Canine Genomes. PMID:31181663
RNA-Seq-Based Gene Expression Pattern and Morphological Alterations in Chick Thymus during Postnatal Development. PMID:31179312
Coding or Noncoding, the Converging Concepts of RNAs. PMID:31178900
Exosomes as carriers transporting long non‑coding RNAs: Molecular characteristics and their function in cancer (Review). PMID:31173220
Functional impacts of non-coding RNA processing on enhancer activity and target gene expression. PMID:31169884
Comparative Analysis of Circulating Noncoding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury. PMID:31159652
OTUD6B-AS1 Might Be a Novel Regulator of Apoptosis in Systemic Sclerosis. PMID:31156645
The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency. PMID:31151411
LnCompare: gene set feature analysis for human long non-coding RNAs. PMID:31147707
Long non-coding RNAs in the spinal cord injury: Novel spotlight. PMID:31140726
LIN28A-stabilized FBXL19-AS1 promotes breast cancer migration, invasion and EMT by regulating WDR66. PMID:31140103
The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection. PMID:31138702
A long noncoding RNA cluster-based genomic locus maintains proper development and visual function. PMID:31127312
Long Noncoding RNAs in the Pathophysiology of Ischemic Stroke. PMID:31119646
Screening key lncRNAs for human rectal adenocarcinoma based on lncRNA-mRNA functional synergistic network. PMID:31116002
Long non-coding RNAs in genitourinary malignancies: a whole new world. PMID:31110275
Nonlinear sequence similarity between the Xist and Rsx long noncoding RNAs suggests shared functions of tandem repeat domains. PMID:31097619
Molecular pattern of lncRNAs in hepatocellular carcinoma. PMID:31097003
Genomic data mining for functional annotation of human long noncoding RNAs. PMID:31090273
LINC00857 knockdown inhibits cell proliferation and induces apoptosis via involving STAT3 and MET oncogenic proteins in esophageal adenocarcinoma. PMID:31085800
Comprehensive characterization of cancer-testis genes in testicular germ cell tumor. PMID:31070303
Improved annotation of the domestic pig genome through integration of Iso-Seq and RNA-seq data. PMID:31064321
The long non-coding RNA ANRASSF1 in the regulation of alternative protein-coding transcripts RASSF1A and RASSF1C in human breast cancer cells: implications to epigenetic therapy. PMID:31062660
Epigenetics of hepatocellular carcinoma. PMID:31056726
Long Noncoding RNAs in Host-Pathogen Interactions. PMID:31053495
Non-Coding RNA Networks in ALK-Positive Anaplastic-Large Cell Lymphoma. PMID:31052302
Cellular functions of long noncoding RNAs. PMID:31048766
Illuminating Genomic Dark Matter with RNA Imaging. PMID:31043413
Identification and characterization of pineapple leaf lncRNAs in crassulacean acid metabolism (CAM) photosynthesis pathway. PMID:31040312
Targeted, High-Resolution RNA Sequencing of Non-coding Genomic Regions Associated With Neuropsychiatric Functions. PMID:31031799
Non-Coding RNAs as New Therapeutic Targets in the Context of Renal Fibrosis. PMID:31018516
An integrated analysis reveals the oncogenic function of lncRNA LINC00511 in human ovarian cancer. PMID:31016892
Long noncoding RNAs: Novel regulators of virus-host interactions. PMID:31016795
Potential Role of lncRNA H19 as a Cancer Biomarker in Human Cancers Detection and Diagnosis: A Pooled Analysis Based on 1585 Subjects. PMID:31016202
Long Non-Coding RNAs and the Innate Immune Response. PMID:31010202
Long Noncoding RNA and Epithelial Mesenchymal Transition in Cancer. PMID:31003545
Interplay Between ncRNAs and Cellular Communication: A Proposal for Understanding Cell-Specific Signaling Pathways. PMID:31001323
Transcriptomic Analysis of Potential "lncRNA-mRNA" Interactions in Liver of the Marine Teleost Cynoglossus semilaevis Fed Diets With Different DHA/EPA Ratios. PMID:31001132
LINC01354 interacting with hnRNP-D contributes to the proliferation and metastasis in colorectal cancer through activating Wnt/β-catenin signaling pathway. PMID:30987669
An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats. PMID:30987022
The role of the protein-RNA recognition code in neurodegeneration. PMID:30980111
lncRedibly versatile: biochemical and biological functions of long noncoding RNAs. PMID:30971458
Gene amplification derived a cancer-testis long noncoding RNA PCAT6 regulates cell proliferation and migration in hepatocellular carcinoma. PMID:30968586
The Regulatory Role of Long Noncoding RNAs in Different Brain Cell Types Involved in Ischemic Stroke. PMID:30967760
Comparative Transcriptomics Reveal Key Sheep (Ovis aries) Hypothalamus LncRNAs that Affect Reproduction. PMID:30965601
Comprehensive analysis of differentially expressed profiles and reconstruction of a competing endogenous RNA network in papillary renal cell carcinoma. PMID:30957192
Gene Expression Pattern and Regulatory Network of α-Toxin Treatment in Bombyx mori. PMID:30956974
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes. PMID:30952905
Silencing an insulin-induced lncRNA, LncASIR, impairs the transcriptional response to insulin signalling in adipocytes. PMID:30948776
Elevation of circular RNA circ_0005230 facilitates cell growth and metastasis via sponging miR-1238 and miR-1299 in cholangiocarcinoma. PMID:30946694
KCNQ1OT1 promotes autophagy by regulating miR-200a/FOXO3/ATG7 pathway in cerebral ischemic stroke. PMID:30945454
Identification of Long Noncoding RNAs in the Developing Endosperm of Maize. PMID:30945178
The lncRNA Neat1 promotes activation of inflammasomes in macrophages. PMID:30940803
Long noncoding RNAs: a missing link in osteoporosis. PMID:30937214
Long Noncoding RNAs: Emerging Players in Medulloblastoma. PMID:30923703
Integrated analysis of lncRNA and mRNA repertoires in Marek's disease infected spleens identifies genes relevant to resistance. PMID:30922224
Systematic benchmarking of omics computational tools. PMID:30918265
SSS-test: a novel test for detecting positive selection on RNA secondary structure. PMID:30898084
Silencing the lncRNA Maclpil in pro-inflammatory macrophages attenuates acute experimental ischemic stroke via LCP1 in mice. PMID:30895879
Long non-coding RNAs: Functional regulatory players in breast cancer. PMID:30891536
Identification and Functional Prediction of Long Intergenic Non-coding RNAs Related to Subcutaneous Adipose Development in Pigs. PMID:30886630
Analysis of lncRNA-Mediated ceRNA Crosstalk and Identification of Prognostic Signature in Head and Neck Squamous Cell Carcinoma. PMID:30886579
Long Noncoding RNA MPRL Promotes Mitochondrial Fission and Cisplatin Chemosensitivity via Disruption of Pre-miRNA Processing. PMID:30885939
Overexpressing Long Noncoding RNAs Using Gene-activating CRISPR. PMID:30882798
Long Noncoding RNA and Protein Interactions: From Experimental Results to Computational Models Based on Network Methods. PMID:30875752
The role of long non-coding RNAs in the pathogenesis of hereditary diseases. PMID:30871545
Volatile Evolution of Long Non-Coding RNA Repertoire in Retinal Pigment Epithelium: Insights from Comparison of Bovine and Human RNA Expression Profiles. PMID:30857256
Long Non-Coding RNA Review and Implications in Lung Diseases. PMID:30854513
Harnessing adipogenesis to prevent obesity. PMID:30848691
LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer. PMID:30846486
Analysis and preliminary validation of the molecular mechanism of fat deposition in fatty and lean pigs by high-throughput sequencing. PMID:30843090
Multi-Omics Approaches to Study Long Non-coding RNA Function in Atherosclerosis. PMID:30838214
CRISPR links to long noncoding RNA function in mice: A practical approach. PMID:30822570
A splice-site variant in the lncRNA gene RP1-140A9.1 cosegregates in the large Volkmann cataract family. PMID:30820140
Long noncoding RNAs and the regulation of innate immunity and host-virus interactions. PMID:30817056
Long non-coding RNAs as pan-cancer master gene regulators of associated protein-coding genes: a systems biology approach. PMID:30809433
LINC00261 Is an Epigenetically Regulated Tumor Suppressor Essential for Activation of the DNA Damage Response. PMID:30796052
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition. PMID:30795783
Long Non-Coding RNAs in the Regulation of Gene Expression: Physiology and Disease. PMID:30781588
Beyond protein-coding genes. PMID:30777838
Identification of functional long non-coding RNAs in C. elegans. PMID:30777050
Long noncoding RNAs: p53's secret weapon in the fight against cancer? PMID:30759134
Predictive models of subcellular localization of long RNAs. PMID:30745363
Multi-tissue observation of the long non-coding RNA effects on sexually biased gene expression in cattle. PMID:30744377
LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus. PMID:30741632
LCAL1 enhances lung cancer survival via inhibiting AMPK-related antitumor functions. PMID:30741368
The Opening of Pandora's Box: An Emerging Role of Long Noncoding RNA in Viral Infections. PMID:30740112
The functional roles of exosomes-derived long non-coding RNA in human cancer. PMID:30739532
LEF1-AS1 contributes to proliferation and invasion through regulating miR-544a/ FOXP1 axis in lung cancer. PMID:30734202
Comparison of RNA-Seq and Microarray Gene Expression Platforms for the Toxicogenomic Evaluation of Liver From Short-Term Rat Toxicity Studies. PMID:30723492
Long non-coding RNA repertoire and open chromatin regions constitute midbrain dopaminergic neuron - specific molecular signatures. PMID:30723217
RNA-Seq profiling in peripheral blood mononuclear cells of amyotrophic lateral sclerosis patients and controls. PMID:30720798
Targeted expression profiling by RNA-Seq improves detection of cellular dynamics during pregnancy and identifies a role for T cells in term parturition. PMID:30696862
The functional roles of exosomal long non-coding RNAs in cancer. PMID:30683984
High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity. PMID:30683753
Long Non-Coding RNAs in Multiple Myeloma. PMID:30682861
Rapid Generation of Long Noncoding RNA Knockout Mice Using CRISPR/Cas9 Technology. PMID:30678101
Long non-coding RNAs in hematopoietic regulation. PMID:30671227
Mechanisms of Antisense Transcription Initiation with Implications in Gene Expression, Genomic Integrity and Disease Pathogenesis. PMID:30669611
LncRNA Riken-201 and Riken-203 modulates neural development by regulating the Sox6 through sequestering miRNAs. PMID:30667104
New Insights into the Interplay between Non-Coding RNAs and RNA-Binding Protein HnRNPK in Regulating Cellular Functions. PMID:30658384
Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network. PMID:30649422
Expression of long non-coding RNA ENSG00000226738 (LncKLHDC7B) is enriched in the immunomodulatory triple-negative breast cancer subtype and its alteration promotes cell migration, invasion, and resistance to cell death. PMID:30648789
Propofol Suppresses Proinflammatory Cytokine Production by Increasing ABCA1 Expression via Mediation by the Long Noncoding RNA LOC286367. PMID:30647536
Oligonucleotide Therapeutics as a New Class of Drugs for Malignant Brain Tumors: Targeting mRNAs, Regulatory RNAs, Mutations, Combinations, and Beyond. PMID:30644073
Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells. PMID:30643116
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia. PMID:30642353
Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in mice. PMID:30641298
Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes. PMID:30639214
Invited Review: Long non-coding RNAs: important regulators in the development, function and disorders of the central nervous system. PMID:30636336
Gammaherpesvirus Readthrough Transcription Generates a Long Non-Coding RNA That Is Regulated by Antisense miRNAs and Correlates with Enhanced Lytic Replication In Vivo. PMID:30634714
Immune-inducible non-coding RNA molecule lincRNA-IBIN connects immunity and metabolism in Drosophila melanogaster. PMID:30633769
BLNCR is a long non-coding RNA adjacent to integrin beta-1 that is rapidly lost during epidermal progenitor cell differentiation. PMID:30631104
TP53LNC-DB, the database of lncRNAs in the p53 signalling network. PMID:30624647
The Role of Histone Methyltransferases and Long Non-coding RNAs in the Regulation of T Cell Fate Decisions. PMID:30619315
Identification of long non-coding RNAs expressed in knee and hip osteoarthritic cartilage. PMID:30611906
Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases. PMID:30610612
Neuronal sub-compartmentalization: a strategy to optimize neuronal function. PMID:30609235
Long non-coding RNA in stem cell pluripotency and lineage commitment: functions and evolutionary conservation. PMID:30607432
Roles of Oncogenic Long Non-coding RNAs in Cancer Development. PMID:30602079
Novel link prediction for large-scale miRNA-lncRNA interaction network in a bipartite graph. PMID:30598112
BC200 RNA: An Emerging Therapeutic Target and Diagnostic Marker for Human Cancer. PMID:30590906
Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs. PMID:30587508
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers. PMID:30586386
Extracellular Vesicles as Conduits of Non-Coding RNA Emission and Intercellular Transfer in Brain Tumors. PMID:30585246
Development and internal validation of a nine-lncRNA prognostic signature for prediction of overall survival in colorectal cancer patients. PMID:30564521
lncRNA involvement in hepatocellular carcinoma metastasis and prognosis. PMID:30564069
Co-expression of long non-coding RNAs and autism risk genes in the developing human brain. PMID:30547845
Non-coding RNAs Function as Immune Regulators in Teleost Fish. PMID:30546368
Long noncoding RNAs of single hematopoietic stem and progenitor cells in healthy and dysplastic human bone marrow. PMID:30545929
Brain Theranostics and Radiotheranostics: Exosomes and Graphenes In Vivo as Novel Brain Theranostics. PMID:30538772
Identification and characterization of novel conserved RNA structures in Drosophila. PMID:30537930
NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found? PMID:30533572
Analyses of long non-coding RNA and mRNA profiling in the spleen of diarrheic piglets caused by Clostridium perfringens type C. PMID:30533301
lncITPF Promotes Pulmonary Fibrosis by Targeting hnRNP-L Depending on Its Host Gene ITGBL1. PMID:30528088
Human Models Are Needed for Studying Human Neurodevelopmental Disorders. PMID:30526865
Variant of SNP rs1317082 at CCSlnc362 (RP11-362K14.5) creates a binding site for miR-4658 and diminishes the susceptibility to CRC. PMID:30518759
Interactome determination of a Long Noncoding RNA implicated in Embryonic Stem Cell Self-Renewal. PMID:30514857
Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture. PMID:30512195
Hepatic transcriptome analysis from HFD-fed mice defines a long noncoding RNA regulating cellular cholesterol levels. PMID:30504232
A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability. PMID:30496290
A novel lncRNA-miRNA-mRNA network analysis identified the hub lncRNA RP11-159F24.1 in the pathogenesis of papillary thyroid cancer. PMID:30474931
The Role of Long Noncoding RNAs in Diabetic Alzheimer's Disease. PMID:30469430
Modulating the expression of long non-coding RNAs for functional studies. PMID:30467236
Coordinate regulation of long non-coding RNAs and protein-coding genes in germ-free mice. PMID:30463508
Gene Ontology-based function prediction of long non-coding RNAs using bi-random walk. PMID:30453964
Intricate crosstalk between MYC and non-coding RNAs regulates hallmarks of cancer. PMID:30451365
Production of Spliced Long Noncoding RNAs Specifies Regions with Increased Enhancer Activity. PMID:30447999
Transcriptome Analysis of Long Non-Coding RNA in the Bovine Mammary Gland Following Dietary Supplementation with Linseed Oil and Safflower Oil. PMID:30445766
Splicing of long non-coding RNAs primarily depends on polypyrimidine tract and 5' splice-site sequences due to weak interactions with SR proteins. PMID:30445574
Sendai Virus Infection Induces Expression of Novel RNAs in Human Cells. PMID:30429577
Genome-wide identification and functional prediction of tobacco lncRNAs responsive to root-knot nematode stress. PMID:30427847
IRSOM, a reliable identifier of ncRNAs based on supervised self-organizing maps with rejection. PMID:30423081
Long Noncoding RNA FEZF1-AS1 Promotes Proliferation and Inhibits Apoptosis in Ovarian Cancer by Activation of JAK-STAT3 Pathway. PMID:30416194
A Potential Competitive Endogenous RNA Pathway Involved in Chronic Spinal Cord Injury. PMID:30411720
H19 Is Expressed in Hybrid Hepatocyte Nuclear Factor 4α+ Periportal Hepatocytes but Not Cytokeratin 19+ Cholangiocytes in Cholestatic Livers. PMID:30411082
Changes in long non-coding RNA expression profiles related to the antagonistic effects of Escherichia coli F17 on lamb spleens. PMID:30410073
BioInstaller: a comprehensive R package to construct interactive and reproducible biological data analysis applications based on the R platform. PMID:30402350
Prediction of LncRNA Subcellular Localization with Deep Learning from Sequence Features. PMID:30401954
Detection of long non-coding RNA homology, a comparative study on alignment and alignment-free metrics. PMID:30400819
Genome-wide screening for functional long noncoding RNAs in human cells by Cas9 targeting of splice sites. PMID:30395134
Non-coding RNA Expression, Function, and Variation during Drosophila Embryogenesis. PMID:30393032
A Prognostic Signature for Lower Grade Gliomas Based on Expression of Long Non-Coding RNAs. PMID:30392137
RPAD (RNase R treatment, polyadenylation, and poly(A)+ RNA depletion) method to isolate highly pure circular RNA. PMID:30391514
Autism spectrum disorder: insights into convergent mechanisms from transcriptomics. PMID:30390048
The RNA world of human ageing. PMID:30386939
Long non-coding RNA: its evolutionary relics and biological implications in mammals: a review. PMID:30386629
Sequence Determinants for Nuclear Retention and Cytoplasmic Export of mRNAs and lncRNAs. PMID:30386371
Non-Coding RNAs and Hepatitis C Virus-Induced Hepatocellular Carcinoma. PMID:30380697
LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse. PMID:30380072
LNCipedia 5: towards a reference set of human long non-coding RNAs. PMID:30371849
Arena-Idb: a platform to build human non-coding RNA interaction networks. PMID:30367585
GENCODE reference annotation for the human and mouse genomes. PMID:30357393
Connivance, Complicity, or Collusion? The Role of Noncoding RNAs in Promoting Gammaherpesvirus Tumorigenesis. PMID:30352676
Global long non-coding RNA expression in the rostral anterior cingulate cortex of depressed suicides. PMID:30337518
Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury. PMID:30335683
ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA. PMID:30335154
Long noncoding RNA Z38 promotes cell proliferation and metastasis and inhibits cell apoptosis in human gastric cancer. PMID:30333877
LncBook: a curated knowledgebase of human long non-coding RNAs. PMID:30329098
Long intergenic noncoding RNAs in cardiovascular diseases: Challenges and strategies for physiological studies and translation. PMID:30316538
Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancer. PMID:30314898
Genome-wide identification of oil biosynthesis-related long non-coding RNAs in allopolyploid Brassica napus. PMID:30314449
Accurate prediction of protein-lncRNA interactions by diffusion and HeteSim features across heterogeneous network. PMID:30309340
Expression analysis of lncRNA AK370814 involved in the barley vitamin B6 salvage pathway under salinity. PMID:30298351
Copaifera langsdorffii Novel Putative Long Non-Coding RNAs: Interspecies Conservation Analysis in Adaptive Response to Different Biomes. PMID:30297664
Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function. PMID:30297415
LncRNAs in TGF-β-Driven Tissue Fibrosis. PMID:30287731
Genome-wide identification and differentially expression analysis of lncRNAs in tilapia. PMID:30286721
CRISPRlnc: a manually curated database of validated sgRNAs for lncRNAs. PMID:30285246
Significant association of long non-coding RNAs HOTAIR genetic polymorphisms with cancer recurrence and patient survival in patients with uterine cervical cancer. PMID:30275757
CD38 is methylated in prostate cancer and regulates extracellular NAD. PMID:30258629
Long noncoding RNA ROR promotes breast cancer by regulating the TGF-β pathway. PMID:30250400
Young genes have distinct gene structure, epigenetic profiles, and transcriptional regulation. PMID:30232198
UPA-seq: prediction of functional lncRNAs using differential sensitivity to UV crosslinking. PMID:30232101
Long Noncoding RNA Signatures Induced by Toll-Like Receptor 7 and Type I Interferon Signaling in Activated Human Plasmacytoid Dendritic Cells. PMID:30230983
Genome-wide identification of tissue-specific long non-coding RNA in three farm animal species. PMID:30227846
Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer. PMID:30227220
Functional classification of long non-coding RNAs by k-mer content. PMID:30224646
lncSLdb: a resource for long non-coding RNA subcellular localization. PMID:30219837
Upregulation of lncRNA ADAMTS9-AS2 Promotes Salivary Adenoid Cystic Carcinoma Metastasis via PI3K/Akt and MEK/Erk Signaling. PMID:30217729
Long Non-Coding RNAs in Gliomas: From Molecular Pathology to Diagnostic Biomarkers and Therapeutic Targets. PMID:30217088
Transcriptomic signature associated with carcinogenesis and aggressiveness of papillary thyroid carcinoma. PMID:30214625
The RNA exosome contributes to gene expression regulation during stem cell differentiation. PMID:30212902
The human adrenal cortex: growth control and disorders. PMID:30208164
De novo assembly, characterization, functional annotation and expression patterns of the black tiger shrimp (Penaeus monodon) transcriptome. PMID:30202061
Recurrence-Associated Long Non-coding RNA Signature for Determining the Risk of Recurrence in Patients with Colon Cancer. PMID:30195788
Characterisation and functional predictions of canine long non-coding RNAs. PMID:30194329
LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat. PMID:30190464
Global Long Noncoding RNA and mRNA Expression Changes between Prenatal and Neonatal Lung Tissue in Pigs. PMID:30189656
EGR1-Mediated Transcription of lncRNA-HNF1A-AS1 Promotes Cell-Cycle Progression in Gastric Cancer. PMID:30185552
Shedding Light on the Dark Cancer Genomes: Long Noncoding RNAs as Novel Biomarkers and Potential Therapeutic Targets for Cancer. PMID:30181330
Transcriptomic analysis reveals key lncRNAs associated with ribosomal biogenesis and epidermis differentiation in head and neck squamous cell carcinoma. PMID:30178634
BC200 (BCYRN1) - The shortest, long, non-coding RNA associated with cancer. PMID:30175286
Long non-coding RNAs in the failing heart and vasculature. PMID:30175285
Exploring the mechanisms behind long noncoding RNAs and cancer. PMID:30175284
The noncoding-RNA landscape in cardiovascular health and disease. PMID:30159435
LncRNA secondary structure in the cardiovascular system. PMID:30159432
The roles of non-coding RNAs in cardiac regenerative medicine. PMID:30159427
Small non-coding RNAs as regulators of structural evolution and carcinogenesis. PMID:30159425
Non-coding RNAs in skeletal muscle regeneration. PMID:30159421
Integrated analysis of dysregulated lncRNA expression in breast cancer cell identified by RNA-seq study. PMID:30159409
A General Overview on Non-coding RNA-Based Diagnostic and Therapeutic Approaches for Liver Diseases. PMID:30158867
Overexpressing lncRNA LAIR increases grain yield and regulates neighbouring gene cluster expression in rice. PMID:30158538
Multi-leveled suppression of p53 function by HuR IncRNPs. PMID:30148260
Exosomal lncRNAs as new players in cell-to-cell communication. PMID:30148073
Circulating exosomal long noncoding RNA PRINS-First findings in monoclonal gammopathies. PMID:30144133
A compendium of conserved cleavage and polyadenylation events in mammalian genes. PMID:30143597
Long Non-Coding RNA-Mediated Regulation of the Interferon Response: A New Perspective on a Familiar Theme. PMID:30135954
Long Non-Coding RNAs Guide the Fine-Tuning of Gene Regulation in B-Cell Development and Malignancy. PMID:30134619
HOXA10‑AS: A novel oncogenic long non‑coding RNA in glioma. PMID:30132568
Dysregulation of lncRNAs GM5524 and GM15645 involved in high‑glucose‑induced podocyte apoptosis and autophagy in diabetic nephropathy. PMID:30132544
LncRNA-ECM is overexpressed in esophageal squamous cell carcinoma and promotes tumor metastasis. PMID:30128011
The long non-coding RNA FLJ46906 binds to the transcription factors NF-κB and AP-1 and regulates expression of aging-associated genes. PMID:30125263
Combined Effects of PVT1 and MiR-146a Single Nucleotide Polymorphism on the Lung Function of Smokers with Chronic Obstructive Pulmonary Disease. PMID:30123065
Long non-coding RNAs in brain tumours: Focus on recent epigenetic findings in glioma. PMID:30117678
Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials. PMID:30116729
INFERNO: inferring the molecular mechanisms of noncoding genetic variants. PMID:30113658
Long non-coding RNA HOTAIR promotes tumorigenesis and forecasts a poor prognosis in cholangiocarcinoma. PMID:30111807
Integrated analysis of lncRNA and mRNA expression in rainbow trout families showing variation in muscle growth and fillet quality traits. PMID:30108261
CRISPR-SKIP: programmable gene splicing with single base editors. PMID:30107853
Genome Wide Identification of Novel Long Non-coding RNAs and Their Potential Associations With Milk Proteins in Chinese Holstein Cows. PMID:30105049
The State of Long Non-Coding RNA Biology. PMID:30103474
Non-Coding Transcriptome Maps across Twenty Tissues of the Korean Black Chicken, Yeonsan Ogye. PMID:30103450
Structural characterization of maternally expressed gene 3 RNA reveals conserved motifs and potential sites of interaction with polycomb repressive complex 2. PMID:30102382
Targeting the FOXM1-regulated long noncoding RNA TUG1 in osteosarcoma. PMID:30099814
LncFinder: an integrated platform for long non-coding RNA identification utilizing sequence intrinsic composition, structural information and physicochemical property. PMID:30084867
Roles of Long Noncoding RNAs and Circular RNAs in Translation. PMID:30082465
Analysis of diet-induced differential methylation, expression, and interactions of lncRNA and protein-coding genes in mouse liver. PMID:30069000
Knockdown of long noncoding RNA GHET1 inhibits cell‑cycle progression and invasion of gastric cancer cells. PMID:30066922
Transcriptomic differential lncRNA expression is involved in neuropathic pain in rat dorsal root ganglion after spared sciatic nerve injury. PMID:30066726
High resolution annotation of zebrafish transcriptome using long-read sequencing. PMID:30061115
HDncRNA: a comprehensive database of non-coding RNAs associated with heart diseases. PMID:30053237
Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data. PMID:30041657
Long noncoding RNA Sox2ot and transcription factor YY1 co-regulate the differentiation of cortical neural progenitors by repressing Sox2. PMID:30038234
Formation of a Family of Long Intergenic Noncoding RNA Genes with an Embedded Translocation Breakpoint Motif in Human Chromosomal Low Copy Repeats of 22q11.2-Some Surprises and Questions. PMID:30036931
The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma. PMID:30026510
TLHNMDA: Triple Layer Heterogeneous Network Based Inference for MiRNA-Disease Association Prediction. PMID:30018632
Deciphering Non-coding RNAs in Cardiovascular Health and Disease. PMID:30013975
The lncRNA male-specific abdominal plays a critical role in Drosophila accessory gland development and male fertility. PMID:30011265
Inherited Cardiomyopathies and the Role of Mutations in Non-coding Regions of the Genome. PMID:29998127
[Analysis of orthologous lncRNAs in humans and mice and their species-specific epigenetic target genes]. PMID:29997097
Atlas of Schistosoma mansoni long non-coding RNAs and their expression correlation to protein-coding genes. PMID:29992321
Bibliometric Analysis of Global Scientific Research on lncRNA: A Swiftly Expanding Trend. PMID:29992161
Colorectal neoplasia differentially expressed: a long noncoding RNA with an imperative role in cancer. PMID:29988699
Dysregulated Expression of Long Intergenic Non-coding RNAs (LincRNAs) in Urothelial Bladder Carcinoma. PMID:29988223
A Novel Probability Model for LncRNA⁻Disease Association Prediction Based on the Naïve Bayesian Classifier. PMID:29986541
Long non-coding RNAs: implications in targeted diagnoses, prognosis, and improved therapeutic strategies in human non- and triple-negative breast cancer. PMID:29983835
Loose ends: almost one in five human genes still have unresolved coding status. PMID:29982784
A current view on long noncoding RNAs in yeast and filamentous fungi. PMID:29974182
Preliminary RNA-Seq Analysis of Long Non-Coding RNAs Expressed in Human Term Placenta. PMID:29954144
Identification of novel mRNAs and lncRNAs associated with mouse experimental colitis and human inflammatory bowel disease. PMID:29953254
Gene Regulatory Network Perturbation by Genetic and Epigenetic Variation. PMID:29941230
Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization. PMID:29937433
Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer. PMID:29931370
Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism. PMID:29925637
Identification of differential expressed lncRNAs in human thyroid cancer by a genome-wide analyses. PMID:29923329
Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast. PMID:29914874
Host Long Noncoding RNA lncRNA-PAAN Regulates the Replication of Influenza A Virus. PMID:29914164
Integrative Analysis of Dysregulated lncRNA-Associated ceRNA Network Reveals Functional lncRNAs in Gastric Cancer. PMID:29912172
Genome-wide analysis of long non-coding RNAs affecting roots development at an early stage in the rice response to cadmium stress. PMID:29902991
Role of non-coding RNAs in non-aging-related neurological disorders. PMID:29898036
Analysis of Differential Expressions of Long Non-coding RNAs in Nasopharyngeal Carcinoma Using Next-generation Deep Sequencing. PMID:29896278
ALUminating the Path of Atherosclerosis Progression: Chaos Theory Suggests a Role for Alu Repeats in the Development of Atherosclerotic Vascular Disease. PMID:29895733
The circulating non-coding RNA landscape for biomarker research: lessons and prospects from cardiovascular diseases. PMID:29877319
Chromatin Landscape Distinguishes the Genomic Loci of Hundreds of Androgen-Receptor-Associated LincRNAs From the Loci of Non-associated LincRNAs. PMID:29875794
High-Quality Genome Assemblies Reveal Long Non-coding RNAs Expressed in Ant Brains. PMID:29874592
The Role of MicroRNAs in Kidney Disease. PMID:29861424
"Pocket-sized RNA-Seq": A Method to Capture New Mature microRNA Produced from a Genomic Region of Interest. PMID:29861419
A Deep Learning Framework for Robust and Accurate Prediction of ncRNA-Protein Interactions Using Evolutionary Information. PMID:29858068
High expression of long non-coding RNA MALAT1 in breast cancer is associated with poor relapse-free survival. PMID:29845475
Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response. PMID:29844877
Long non-coding RNA NNT-AS1 contributes to cell proliferation, metastasis and apoptosis in human ovarian cancer. PMID:29805655
The lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer. PMID:29795987
Towards a complete map of the human long non-coding RNA transcriptome. PMID:29795125
Non-coding RNAs in Various Stages of Liver Disease Leading to Hepatocellular Carcinoma: Differential Expression of miRNAs, piRNAs, lncRNAs, circRNAs, and sno/mt-RNAs. PMID:29789629
The Long Non-Coding RNA RP5-1024C24.1 and Its Associated-Gene MPPED2 Are Down-Regulated in Human Thyroid Neoplasias and Act as Tumour Suppressors. PMID:29783666
Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies. PMID:29777220
The use of long non-coding RNAs as prognostic biomarkers and therapeutic targets in prostate cancer. PMID:29755696
Long noncoding RNA DANCR, working as a competitive endogenous RNA, promotes ROCK1-mediated proliferation and metastasis via decoying of miR-335-5p and miR-1972 in osteosarcoma. PMID:29753317
A novel long non-coding RNA-PRLB acts as a tumor promoter through regulating miR-4766-5p/SIRT1 axis in breast cancer. PMID:29752439
HITS-CLIP reveals sex-differential RNA binding and alterative splicing regulation of SRm160 in Drosophila. PMID:29750417
Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma. PMID:29749396
Regulation of osteogenesis by long noncoding RNAs: An epigenetic mechanism contributing to bone formation. PMID:29745821
Reconstruction and analysis of the aberrant lncRNA-miRNA-mRNA network based on competitive endogenous RNA in CESC. PMID:29741786
Deciphering the roles of lncRNAs in breast development and disease. PMID:29732012
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. PMID:29731168
Epigenetic regulation of long non-coding RNAs in gastric cancer. PMID:29721215
Encoding activities of non-coding RNAs. PMID:29721095
Prediction of plant lncRNA by ensemble machine learning classifiers. PMID:29720103
Long noncoding RNA DANCR promotes colorectal cancer proliferation and metastasis via miR-577 sponging. PMID:29717105
Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression. PMID:29707678
Long non-coding RNAs involved in the regulatory network during porcine pre-implantation embryonic development and iPSC induction. PMID:29703926
Noncoding RNA:RNA Regulatory Networks in Cancer. PMID:29702599
A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma. PMID:29700321
Long non-coding RNA-ROR aggravates myocardial ischemia/reperfusion injury. PMID:29694511
Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin. PMID:29691407
Cross-species inference of long non-coding RNAs greatly expands the ruminant transcriptome. PMID:29690875
Posttranscriptional (Re)programming of Cell Fate: Examples in Stem Cells, Progenitor, and Differentiated Cells. PMID:29686685
Integrative bioinformatics analysis characterizing the role of EDC3 in mRNA decay and its association to intellectual disability. PMID:29685133
Role of microRNAs and Exosomes in Helicobacter pylori and Epstein-Barr Virus Associated Gastric Cancers. PMID:29675003
ncRNA-disease association prediction based on sequence information and tripartite network. PMID:29671405
Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs. PMID:29670884
Analysis of long non-coding RNA (lncRNA) expression in hepatitis B patients. PMID:29669510
A family of long intergenic non-coding RNA genes in human chromosomal region 22q11.2 carry a DNA translocation breakpoint/AT-rich sequence. PMID:29668722
A Catalogue of Putative cis-Regulatory Interactions Between Long Non-coding RNAs and Proximal Coding Genes Based on Correlative Analysis Across Diverse Human Tumors. PMID:29666194
Identification and Functional Analysis of Long Intergenic Non-coding RNAs Underlying Intramuscular Fat Content in Pigs. PMID:29662503
Sponge Long Non-Coding RNAs Are Expressed in Specific Cell Types and Conserved Networks. PMID:29657303
Besides Pathology: Long Non-Coding RNA in Cell and Tissue Homeostasis. PMID:29657300
Rare Splice Variants in Long Non-Coding RNAs. PMID:29657294
Present Scenario of Long Non-Coding RNAs in Plants. PMID:29657289
Vesiculated Long Non-Coding RNAs: Offshore Packages Deciphering Trans-Regulation between Cells, Cancer Progression and Resistance to Therapies. PMID:29657282
The Ins and Outs of miRNA-Mediated Gene Silencing during Neuronal Synaptic Plasticity. PMID:29657259
Identification of novel lncRNAs regulated by the TAL1 complex in T-cell acute lymphoblastic leukemia. PMID:29654272
Long noncoding RNA: multiple players in gene expression. PMID:29636120
Identification of lncRNA expression profiles and ceRNA analysis in the spinal cord of morphine-tolerant rats. PMID:29636075
Profiling expression of coding genes, long noncoding RNA, and circular RNA in lung adenocarcinoma by ribosomal RNA-depleted RNA sequencing. PMID:29632808
Profiling of Long Non-coding RNAs and mRNAs by RNA-Sequencing in the Hippocampi of Adult Mice Following Propofol Sedation. PMID:29628875
A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1. PMID:29618024
Long non-coding regulatory RNAs in sponges and insights into the origin of animal multicellularity. PMID:29616867
Signatures of Long-Term Balancing Selection in Human Genomes. PMID:29608730
Genomic Effects of the Vitamin D Receptor: Potentially the Link between Vitamin D, Immune Cells, and Multiple Sclerosis. PMID:29593729
A long noncoding RNA promotes cellulase expression in Trichoderma reesei. PMID:29588663
Identification of small ORF-encoded peptides in mouse serum. PMID:29577068
Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells. PMID:29562912
Role of Genetics and Epigenetics in the Pathogenesis of Alzheimer's Disease and Frontotemporal Dementia. PMID:29562532
The Ever-Evolving Concept of the Gene: The Use of RNA/Protein Experimental Techniques to Understand Genome Functions. PMID:29560353
Long Non-Coding RNAs Responsive to Salt and Boron Stress in the Hyper-Arid Lluteño Maize from Atacama Desert. PMID:29558449
Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma. PMID:29556360
Upregulated long non-coding RNA SBF2-AS1 promotes proliferation in esophageal squamous cell carcinoma. PMID:29552140
Non-coding RNA regulation of endothelial and macrophage functions during atherosclerosis. PMID:29551552
Long non-coding RNAs regulating macrophage functions in homeostasis and disease. PMID:29548902
Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci. PMID:29540241
Sleep Deprivation and the Epigenome. PMID:29535611
LncKdm2b controls self-renewal of embryonic stem cells via activating expression of transcription factor Zbtb3. PMID:29535137
The Role of Non-Coding RNAs and Isothiocyanates in Cancer. PMID:29532604
Integrative analysis of competing endogenous RNA network focusing on long noncoding RNA associated with progression of cutaneous melanoma. PMID:29522273
Cytoplasmic functions of long noncoding RNAs. PMID:29516680
Multi-tissue transcriptomic study reveals the main role of liver in the chicken adaptive response to a switch in dietary energy source through the transcriptional regulation of lipogenesis. PMID:29514634
Integration of lncRNA and mRNA Transcriptome Analyses Reveals Genes and Pathways Potentially Involved in Calf Intestinal Growth and Development during the Early Weeks of Life. PMID:29510583
The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway. PMID:29504607
CTD-2020K17.1, a Novel Long Non-Coding RNA, Promotes Migration, Invasion, and Proliferation of Serous Ovarian Cancer Cells In Vitro. PMID:29504606
Regulation of the Interferon Response by lncRNAs in HCV Infection. PMID:29503633
The Role of Long Non-Coding RNAs in Hepatocarcinogenesis. PMID:29495592
No way out: when RNA elements promote nuclear retention. PMID:29487065
Fam60al as a novel factor involved in reprogramming of somatic cell nuclear transfer in zebrafish (Danio rerio). PMID:29483827
Airn Regulates Igf2bp2 Translation in Cardiomyocytes. PMID:29483092
LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction. PMID:29475982
Genome-wide identification and analysis of A-to-I RNA editing events in bovine by transcriptome sequencing. PMID:29470549
The Unexpected Tuners: Are LncRNAs Regulating Host Translation during Infections? PMID:29469820
Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells. PMID:29466324
Luminal lncRNAs Regulation by ERα-Controlled Enhancers in a Ligand-Independent Manner in Breast Cancer Cells. PMID:29462945
Cas9-mediated excision of proximal DNaseI/H3K4me3 signatures confers robust silencing of microRNA and long non-coding RNA genes. PMID:29451908
Long non-coding RNAs in ischemic stroke. PMID:29449542
Therapeutic Targeting of Long Non-Coding RNAs in Cancer. PMID:29449148
RNA secondary structure profiling in zebrafish reveals unique regulatory features. PMID:29448945
Insights into the roles of lncRNAs in skeletal and dental diseases. PMID:29441193
Upregulation of LncRNA BCYRN1 promotes tumor progression and enhances EpCAM expression in gastric carcinoma. PMID:29435146
The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches. PMID:29434642
Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs. PMID:29434199
lncRNA in HNSCC: challenges and potential. PMID:29416430
Differentially expressed host long intergenic noncoding RNA and mRNA in HIV-1 and HIV-2 infection. PMID:29416066
Long non-coding and coding RNAs characterization in Peripheral Blood Mononuclear Cells and Spinal Cord from Amyotrophic Lateral Sclerosis patients. PMID:29402919
RNA Biology in Retinal Development and Disease. PMID:29395379
Structural analyses of NEAT1 lncRNAs suggest long-range RNA interactions that may contribute to paraspeckle architecture. PMID:29394378
Crosstalk between long non-coding RNAs and Wnt/β-catenin signalling in cancer. PMID:29392884
Lnc-ing non-coding RNAs with metabolism and diabetes: roles of lncRNAs. PMID:29387902
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA. PMID:29386330
Long non-coding RNA MDC1-AS inhibits human gastric cancer cell proliferation and metastasis through an MDC1-dependent mechanism. PMID:29375682
Profiling and Co-expression Network Analysis of Learned Helplessness Regulated mRNAs and lncRNAs in the Mouse Hippocampus. PMID:29375311
Over-expression of oncigenic pesudogene DUXAP10 promotes cell proliferation and invasion by regulating LATS1 and β-catenin in gastric cancer. PMID:29374493
Functional Classification and Experimental Dissection of Long Noncoding RNAs. PMID:29373828
The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells. PMID:29364956
Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease. PMID:29361088
Gene Expression Signatures Characterized by Longitudinal Stability and Interindividual Variability Delineate Baseline Phenotypic Groups with Distinct Responses to Immune Stimulation. PMID:29352003
Comprehensive analysis of mRNA-lncRNA co-expression profile revealing crucial role of imprinted gene cluster DLK1-MEG3 in chordoma. PMID:29348851
Identification of novel diagnostic biomarkers for thyroid carcinoma. PMID:29340074
High-throughput identification of RNA nuclear enrichment sequences. PMID:29335281
Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models. PMID:29333526
Non-coding RNAs in hepatocellular carcinoma: molecular functions and pathological implications. PMID:29317776
Identification of Transposable Elements Contributing to Tissue-Specific Expression of Long Non-Coding RNAs. PMID:29315213
Long Non-coding RNAs in Prostate Cancer with Emphasis on Second Chromosome Locus Associated with Prostate-1 Expression. PMID:29312884
Statistical analysis of non-coding RNA data. PMID:29306017
Natural Antisense Transcripts: Molecular Mechanisms and Implications in Breast Cancers. PMID:29301303
Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions. PMID:29298432
Long noncoding RNA LINP1 acts as an oncogene and promotes chemoresistance in breast cancer. PMID:29293402
LncRNA Structural Characteristics in Epigenetic Regulation. PMID:29292750
Pseudogenes of annexin A2, novel prognosis biomarkers for diffuse gliomas. PMID:29291003
Clinicopathological and Prognostic Role of Long Noncoding RNA Linc00152 in Various Human Neoplasms: Evidence from Meta-Analysis. PMID:29285514
Association between genetic polymorphisms of long non-coding RNA PRNCR1 and prostate cancer risk in a sample of the Iranian population. PMID:29285392
The Long Intergenic Noncoding RNA (LincRNA) Landscape of the Soybean Genome. PMID:29284742
Intergenic disease-associated regions are abundant in novel transcripts. PMID:29284497
Identification of a novel lncRNA induced by the nephrotoxin ochratoxin A and expressed in human renal tumor tissue. PMID:29282485
Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride. PMID:29266543
Non-coding RNAs profiling in head and neck cancers. PMID:29263803
Conserved noncoding transcription and core promoter regulatory code in early Drosophila development. PMID:29260710
The coding and noncoding transcriptome of Neurospora crassa. PMID:29258423
A long non-coding RNA expression signature to predict survival of patients with colon adenocarcinoma. PMID:29254165
A deep learning method for lincRNA detection using auto-encoder algorithm. PMID:29244011
Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking. PMID:29239719
Five key lncRNAs considered as prognostic targets for predicting pancreatic ductal adenocarcinoma. PMID:29239017
[Non-coding RNA : Innovative regulators with therapeutic perspective]. PMID:29236145
Long Non-Coding RNAs: Emerging and Versatile Regulators in Host-Virus Interactions. PMID:29234324
Transcriptome-wide analysis of natural antisense transcripts shows their potential role in breast cancer. PMID:29234122
Pronounced strain-specific chemosensory receptor gene expression in the mouse vomeronasal organ. PMID:29233099
LncRNA as ceRNAs may be involved in lactation process. PMID:29228670
Systematic identification of long non-coding RNAs with cancer-testis expression patterns in 14 cancer types. PMID:29212265
Living Organisms Author Their Read-Write Genomes in Evolution. PMID:29211049
Targeting the long noncoding RNA MALAT1 blocks the pro-angiogenic effects of osteosarcoma and suppresses tumour growth. PMID:29209144
Long noncoding RNAs that respond to Fusarium oxysporum infection in 'Cavendish' banana (Musa acuminata). PMID:29209086
LAST, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote CCND1 mRNA stability in human cells. PMID:29199958
A Novel Y-Specific Long Non-Coding RNA Associated with Cellular Lipid Accumulation in HepG2 cells and Atherosclerosis-related Genes. PMID:29196750
Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome. PMID:29196558
Associations between novel genetic variants in the promoter region of MALAT1 and risk of colorectal cancer. PMID:29190941
Long Non-Coding RNAs in Metabolic Organs and Energy Homeostasis. PMID:29189723
ProphTools: general prioritization tools for heterogeneous biological networks. PMID:29186475
Long non-coding RNAs in Colorectal Cancer: Progression and Future Directions. PMID:29158793
Selecting lncRNAs in gastric cancer cells for directed therapy with bioactive peptides and chemotherapy drugs. PMID:29156779
Development of novel long noncoding RNA MALAT1 near-infrared optical probes for in vivo tumour imaging. PMID:29156758
A genome-wide comprehensively analyses of long noncoding RNA profiling and metastasis associated lncRNAs in renal cell carcinoma. PMID:29152119
Noncoding RNAs in the Regulation of Pluripotency and Reprogramming. PMID:29143182
Genome-wide identification of miRNAs and lncRNAs in Cajanus cajan. PMID:29141604
The functions and unique features of long intergenic non-coding RNA. PMID:29138516
Comprehensive Profiling of lincRNAs in Lung Adenocarcinoma of Never Smokers Reveals Their Roles in Cancer Development and Prognosis. PMID:29137177
Genome-wide analyses of long noncoding RNA expression profiles in lung adenocarcinoma. PMID:29127420
The North American bullfrog draft genome provides insight into hormonal regulation of long noncoding RNA. PMID:29127278
Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head. PMID:29118346
Mechanisms of Long Non-Coding RNAs in the Assembly and Plasticity of Neural Circuitry. PMID:29109677
Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs. PMID:29107980
Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes. PMID:29107288
High-throughput annotation of full-length long noncoding RNAs with capture long-read sequencing. PMID:29106417
Identification and Analysis of P53-Mediated Competing Endogenous RNA Network in Human Hepatocellular Carcinoma. PMID:29104512
The long non-coding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells. PMID:29084806
Promotion of trophoblast invasion by lncRNA MVIH through inducing Jun-B. PMID:29083110
Tissue- and Cell Type-Specific Expression of the Long Noncoding RNA Klhl14-AS in Mouse. PMID:29082235
UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq. PMID:29079769
CeFra-seq reveals broad asymmetric mRNA and noncoding RNA distribution profiles in Drosophila and human cells. PMID:29079635
Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq. PMID:29072160
Expression and regulation of long noncoding RNAs during the osteogenic differentiation of periodontal ligament stem cells in the inflammatory microenvironment. PMID:29070806
LncRNA RP11-436H11.5, functioning as a competitive endogenous RNA, upregulates BCL-W expression by sponging miR-335-5p and promotes proliferation and invasion in renal cell carcinoma. PMID:29070041
Constructing prediction models from expression profiles for large scale lncRNA-miRNA interaction profiling. PMID:29069317
Dysregulated long noncoding RNAs (lncRNAs) in hepatocellular carcinoma: implications for tumorigenesis, disease progression, and liver cancer stem cells. PMID:29061150
Evaluation of fluorescence in situ hybridization techniques to study long non-coding RNA expression in cultured cells. PMID:29059327
A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression. PMID:29059299
Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens. PMID:29055697
The role of long noncoding RNAs in cancer: the dark matter matters. PMID:29054012
Elucidating the Role of Host Long Non-Coding RNA during Viral Infection: Challenges and Paths Forward. PMID:29053596
CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter. PMID:29051223
LncRNAs: key players and novel insights into diabetes mellitus. PMID:29050364
A comprehensive genome-wide analysis of long noncoding RNA expression profile in hepatocellular carcinoma. PMID:29047230
Dynamic Organization of lncRNA and Circular RNA Regulators Collectively Controlled Cardiac Differentiation in Humans. PMID:29037607
Comparative genomic analyses highlight the contribution of pseudogenized protein-coding genes to human lincRNAs. PMID:29037146
Cellular, physiological and pathological aspects of the long non-coding RNA NEAT1. PMID:29033980
HOXD-AS1 functions as an oncogenic ceRNA to promote NSCLC cell progression by sequestering miR-147a. PMID:29033588
The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma. PMID:29029475
Transcriptomic profiling of long non-coding RNAs in hepatitis B virus-related hepatocellular carcinoma. PMID:29029442
Expression Analysis of Long Non-Coding PCAT-1in Breast Cancer. PMID:28989584
Exon Mapping in Long Noncoding RNAs Using Digital Filters. PMID:28989280
Long non-coding RNA SNHG20 promotes non-small cell lung cancer cell proliferation and migration by epigenetically silencing of P21 expression. PMID:28981099
Emerging Properties and Functional Consequences of Noncoding Transcription. PMID:28978770
Noncoding RNA in drug resistant sarcoma. PMID:28978183
Genetic polymorphisms of non-coding RNAs associated with increased head and neck cancer susceptibility: a systematic review and meta-analysis. PMID:28977965
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events. PMID:28959951
Human Long Noncoding RNA Regulation of Stem Cell Potency and Differentiation. PMID:28951743
Small Non-coding RNA Abundance in Adrenocortical Carcinoma: A Footprint of a Rare Cancer. PMID:28943972
Development and validation of nomogram based on lncRNA ZFAS1 for predicting survival in lymph node-negative esophageal squamous cell carcinoma patients. PMID:28938617
A five-long non-coding RNA signature to improve prognosis prediction of clear cell renal cell carcinoma. PMID:28938589
Widespread intra-dependencies in the removal of introns from human transcripts. PMID:28934498
Targeting H19, an Imprinted Long Non-Coding RNA, in Hepatic Functions and Liver Diseases. PMID:28933364
Long non-coding RNAs in hepatocellular carcinoma: Potential roles and clinical implications. PMID:28932078
Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. PMID:28930659
Analysis of long non-coding RNA expression profiles in clear cell renal cell carcinoma. PMID:28928816
Emerging mechanisms of long noncoding RNA function during normal and malignant hematopoiesis. PMID:28928124
Control of Immune Cell Homeostasis and Function by lncRNAs. PMID:28919048
DNA methylation signature of long noncoding RNA genes during human pre-implantation embryonic development. PMID:28915634
Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations. PMID:28912564
PRINS Non-Coding RNA Regulates Nucleic Acid-Induced Innate Immune Responses of Human Keratinocytes. PMID:28900430
Catalog of Differentially Expressed Long Non-Coding RNA following Activation of Human and Mouse Innate Immune Response. PMID:28900427
Long noncoding RNAs in the model species Brachypodium distachyon. PMID:28900227
Knockdown of long non-coding RNA prostate cancer-associated ncRNA transcript 1 inhibits multidrug resistance and c-Myc-dependent aggressiveness in colorectal cancer Caco-2 and HT-29 cells. PMID:28884413
Identification of long non-coding RNAs biomarkers associated with progression of endometrial carcinoma and patient outcomes. PMID:28881755
The Schistosoma mansoni genome encodes thousands of long non-coding RNAs predicted to be functional at different parasite life-cycle stages. PMID:28874839
Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs. PMID:28869604
The Role of Long Non Coding RNAs in the Repair of DNA Double Strand Breaks. PMID:28868264
Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL. PMID:28863214
Noncoding RNAs in neurodegeneration. PMID:28855739
Identification of long non-coding RNA 00312 and 00673 in human NSCLC tissues. PMID:28849087
Short and Long Noncoding RNAs Regulate the Epigenetic Status of Cells. PMID:28847161
Characterization of lincRNA expression in the human retinal pigment epithelium and differentiated induced pluripotent stem cells. PMID:28837677
Analyses of Long Non-Coding RNA and mRNA profiling using RNA sequencing in chicken testis with extreme sperm motility. PMID:28831078
Long Noncoding RNAs as Diagnostic and Therapeutic Targets in Type 2 Diabetes and Related Complications. PMID:28829354
Transcriptome analysis reveals long intergenic non-coding RNAs involved in skeletal muscle growth and development in pig. PMID:28821716
Transcriptome Analysis Reveals Long Intergenic Noncoding RNAs Contributed to Growth and Meat Quality Differences between Yorkshire and Wannanhua Pig. PMID:28820450
Understanding the Role of lncRNAs in Nervous System Development. PMID:28815543
RNA sequencing of db/db mice liver identifies lncRNA H19 as a key regulator of gluconeogenesis and hepatic glucose output. PMID:28814771
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis. PMID:28808260
Identification and characterization of a long non-coding RNA up-regulated during HIV-1 infection. PMID:28803142
Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing. PMID:28801656
The role of interactions of long non-coding RNAs and heterogeneous nuclear ribonucleoproteins in regulating cellular functions. PMID:28801479
A transcriptome atlas of rabbit revealed by PacBio single-molecule long-read sequencing. PMID:28794490
Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer. PMID:28794488
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. PMID:28792927
Comprehensive analysis of differential co-expression patterns reveal transcriptional dysregulation mechanism and identify novel prognostic lncRNAs in esophageal squamous cell carcinoma. PMID:28790843
Long non-coding RNA Fer-1-like family member 4 is overexpressed in human glioblastoma and regulates the tumorigenicity of glioma cells. PMID:28789454
Long non-coding RNAs as novel biomarkers for breast cancer invasion and metastasis. PMID:28789424
Analysis of long non-coding RNA expression profiles in ovarian cancer. PMID:28789375
Long non-coding RNA expression profile in cervical cancer tissues. PMID:28789353
Comprehensive discovery of noncoding RNAs in acute myeloid leukemia cell transcriptomes. PMID:28760689
Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis. PMID:28757239
Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer's disease. PMID:28742084
Long non-coding RNAs as novel players in β cell function and type 1 diabetes. PMID:28738846
Oncogenic long noncoding RNA landscape in breast cancer. PMID:28738804
'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling. PMID:28736855
Toward Understanding Non-coding RNA Roles in Intracranial Aneurysms and Subarachnoid Hemorrhage. PMID:28729919
microRNA dependent and independent deregulation of long non-coding RNAs by an oncogenic herpesvirus. PMID:28715488
Regulatory Roles of Long Non-Coding RNAs in the Central Nervous System and Associated Neurodegenerative Diseases. PMID:28713244
lncRNAs and MYC: An Intricate Relationship. PMID:28704924
Understanding the Role of Non-Coding RNAs in Bladder Cancer: From Dark Matter to Valuable Therapeutic Targets. PMID:28703782
Long noncoding RNA expression profile changes associated with dietary energy in the sheep testis during sexual maturation. PMID:28701734
Spatiotemporal expression profiling of long intervening noncoding RNAs in Caenorhabditis elegans. PMID:28701691
Classification and function of small open reading frames. PMID:28698598
Neuropathology of suicide: recent findings and future directions. PMID:28696430
Genome-wide analysis of long noncoding RNA profiling in PRRSV-infected PAM cells by RNA sequencing. PMID:28694521
Annotation and cluster analysis of spatiotemporal- and sex-related lncRNA expression in rhesus macaque brain. PMID:28687705
Chromatin-enriched lncRNAs: a novel class of enhancer RNAs. PMID:28686230
Long non-coding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients. PMID:28679652
Modeling human disease in rodents by CRISPR/Cas9 genome editing. PMID:28677007
Identification of long non-coding RNA in the horse transcriptome. PMID:28676104
Roles of Non-coding RNAs During Herpesvirus Infection. PMID:28674945
A noncoding RNA containing a SINE-B1 motif associates with meiotic metaphase chromatin and has an indispensable function during spermatogenesis. PMID:28658256
HOTAIR: a key regulator in gynecologic cancers. PMID:28649178
A high-quality annotated transcriptome of swine peripheral blood. PMID:28646867
The Super-Enhancer-Derived alncRNA-EC7/Bloodlinc Potentiates Red Blood Cell Development in trans. PMID:28636939
Long noncoding RNA and its contribution to autism spectrum disorders. PMID:28635106
Long Noncoding RNAs as Biomarkers in Cancer. PMID:28634418
State of the art technologies to explore long non-coding RNAs in cancer. PMID:28631377
Spatio-temporal analysis of coding and long noncoding transcripts during maize endosperm development. PMID:28630499
Identification and characterization of long intergenic noncoding RNAs in bovine mammary glands. PMID:28629368
Prediction of lncRNA-protein interactions using HeteSim scores based on heterogeneous networks. PMID:28623317
Insights from Global Analyses of Long Noncoding RNAs in Breast Cancer. PMID:28616363
Long non-coding RNAs (lncRNAs) and their transcriptional control of inflammatory responses. PMID:28615453
Primate-specific Long Non-coding RNAs and MicroRNAs. PMID:28602844
Genomic Insight into the Role of lncRNA in Cancer Susceptibility. PMID:28598379
Single-cell RNA-sequencing of the brain. PMID:28597408
Computational prediction of lncRNA-mRNA interactionsby integrating tissue specificity in human transcriptome. PMID:28595592
Identification of MyoD-Responsive Transcripts Reveals a Novel Long Non-coding RNA (lncRNA-AK143003) that Negatively Regulates Myoblast Differentiation. PMID:28588232
Microarray expression profiling in the denervated hippocampus identifies long noncoding RNAs functionally involved in neurogenesis. PMID:28587591
Microarray profiling of long non-coding RNAs associated with idiopathic pulmonary arterial hypertension. PMID:28587327
lncRNA-screen: an interactive platform for computationally screening long non-coding RNAs in large genomics datasets. PMID:28583068
Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells. PMID:28579393
LincIN, a novel NF90-binding long non-coding RNA, is overexpressed in advanced breast tumors and involved in metastasis. PMID:28558830
A Review on Recent Computational Methods for Predicting Noncoding RNAs. PMID:28553651
Long non-coding RNA MALAT1 promotes proliferation and suppresses apoptosis of glioma cells through derepressing Rap1B by sponging miR-101. PMID:28551849
Long Noncoding RNA CAMTA1 Promotes Proliferation and Mobility of the Human Breast Cancer Cell Line MDA-MB-231 via Targeting miR-20b. PMID:28550685
A score test for genetic class-level association with nonlinear biomarker trajectories. PMID:28543585
Identification and Characterization of a Class of MALAT1-like Genomic Loci. PMID:28538188
Evolinc: A Tool for the Identification and Evolutionary Comparison of Long Intergenic Non-coding RNAs. PMID:28536600
The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells. PMID:28536419
Mining for Micropeptides. PMID:28528987
Fingerprint of long non-coding RNA regulated by cyclic mechanical stretch in human aortic smooth muscle cells: implications for hypertension. PMID:28526936
Genome-wide identification of lncRNAs associated with chlorantraniliprole resistance in diamondback moth Plutella xylostella (L.). PMID:28506253
Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution. PMID:28500258
The More the Merrier-Complexity in Long Non-Coding RNA Loci. PMID:28487673
Transcriptomics and the Mediterranean Diet: A Systematic Review. PMID:28486416
Identification of aberrantly expressed long non-coding RNAs in stomach adenocarcinoma. PMID:28484081
Comparative transcriptomics in human and mouse. PMID:28479595
Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer. PMID:28473531
LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis. PMID:28472763
Annotating function to differentially expressed LincRNAs in myelodysplastic syndrome using a network-based method. PMID:28472271
Zipper plot: visualizing transcriptional activity of genomic regions. PMID:28464823
Accumulation of GAS5 in exosomes is a marker of apoptosis induction. PMID:28451400
Thousands of RNA-cached copies of whole chromosomes are present in the ciliate Oxytricha during development. PMID:28450531
Orphan CpG islands define a novel class of highly active enhancers. PMID:28448736
New Lncs to mesendoderm specification. PMID:28446963
Long Non-coding RNAs and their Role in Metastasis. PMID:28446530
Meiotic Genes Are Enriched in Regions of Reduced Archaic Ancestry. PMID:28444387
Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer. PMID:28441948
The emergence of noncoding RNAs as Heracles in autophagy. PMID:28441084
Emerging roles for ncRNAs in alcohol use disorders. PMID:28438526
Normalized long read RNA sequencing in chicken reveals transcriptome complexity similar to human. PMID:28438136
Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. PMID:28430919
Models of global gene expression define major domains of cell type and tissue identity. PMID:28426095
LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method. PMID:28425476
Essential role of long non-coding RNAs in de novo chromatin modifications: the genomic address code hypothesis. PMID:28424740
Predictive analysis of long non-coding RNA expression profiles in diffuse large B-cell lymphoma. PMID:28423571
Roles of long noncoding RNAs in colorectal cancer metastasis. PMID:28418892
High-Throughput Sequencing and Co-Expression Network Analysis of lncRNAs and mRNAs in Early Brain Injury Following Experimental Subarachnoid Haemorrhage. PMID:28417961
CRISPR/Cas9-mediated deletion of lncRNA Gm26878 in the distant Foxf1 enhancer region. PMID:28405742
Biotagging of Specific Cell Populations in Zebrafish Reveals Gene Regulatory Logic Encoded in the Nuclear Transcriptome. PMID:28402863
High-confidence coding and noncoding transcriptome maps. PMID:28396519
Long noncoding RNA LINC01296 is associated with poor prognosis in prostate cancer and promotes cancer-cell proliferation and metastasis. PMID:28392705
Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development. PMID:28392072
Perspectives of long non-coding RNAs in cancer. PMID:28391434
Comprehensive analysis of the association between UBAC2 polymorphisms and Behçet's disease in a Japanese population. PMID:28389674
De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14+ monocytes and in adipose tissue. PMID:28389524
LncATLAS database for subcellular localization of long noncoding RNAs. PMID:28386015
Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip. PMID:28384324
Oncogenic effects of evolutionarily conserved noncoding RNA ECONEXIN on gliomagenesis. PMID:28368417
A Comprehensive NGS Data Analysis of Differentially Regulated miRNAs, piRNAs, lncRNAs and sn/snoRNAs in Triple Negative Breast Cancer. PMID:28367238
Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication. PMID:28360889
Exploiting Long Noncoding RNAs as Pharmacological Targets to Modulate Epigenetic Diseases. PMID:28356895
Potentials of Long Noncoding RNAs (LncRNAs) in Sarcoma: From Biomarkers to Therapeutic Targets. PMID:28353666
Exploration of small RNA-seq data for small non-coding RNAs in Human Colorectal Cancer. PMID:28348640
Profiling of long non-coding RNAs identifies LINC00958 and LINC01296 as candidate oncogenes in bladder cancer. PMID:28341852
Identification of long non-coding transcripts with feature selection: a comparative study. PMID:28335739
A class of circadian long non-coding RNAs mark enhancers modulating long-range circadian gene regulation. PMID:28335007
Post-transcriptional and translational regulation of mRNA-like long non-coding RNAs by microRNAs in early developmental stages of zebrafish embryos. PMID:28320503
Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice. PMID:28314781
The Non-Coding Transcriptome of Prostate Cancer: Implications for Clinical Practice. PMID:28299719
An Insight into the Increasing Role of LncRNAs in the Pathogenesis of Gliomas. PMID:28293170
Non-Coding RNAs: New Players in Skin Wound Healing. PMID:28289554
T-ALL and thymocytes: a message of noncoding RNAs. PMID:28270163
Gene expression profiling in the human alcoholic brain. PMID:28254370
Conserved expression of transposon-derived non-coding transcripts in primate stem cells. PMID:28245871
Integrative multi-omics analysis revealed SNP-lncRNA-mRNA (SLM) networks in human peripheral blood mononuclear cells. PMID:28243742
Current Insights into Long Non-Coding RNAs (LncRNAs) in Prostate Cancer. PMID:28241429
An atlas of human long non-coding RNAs with accurate 5' ends. PMID:28241135
Comprehensive analysis of long non-coding RNAs highlights their spatio-temporal expression patterns and evolutional conservation in Sus scrofa. PMID:28233874
Analysis of distinct long noncoding RNA transcriptional fingerprints in pancreatic ductal adenocarcinoma. PMID:28220683
Systems Biology-Derived Discoveries of Intrinsic Clocks. PMID:28220104
Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6. PMID:28216671
UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene. PMID:28215706
Epigenetic Landscape during Coronavirus Infection. PMID:28212305
lncRNA co-expression network model for the prognostic analysis of acute myeloid leukemia. PMID:28204819
Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. PMID:28193769
Challenges of CRISPR/Cas9 applications for long non-coding RNA genes. PMID:28180319
Reciprocal regulation of chromatin state and architecture by HOTAIRM1 contributes to temporal collinear HOXA gene activation. PMID:28180285
The crosstalk between long non-coding RNAs and PI3K in cancer. PMID:28176240
The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance. PMID:28160600
Variable Levels of Long Noncoding RNA Expression in DNA Mismatch Repair-Proficient Early-Stage Colon Cancer. PMID:28160106
The HOTAIR, PRNCR1 and POLR2E polymorphisms are associated with cancer risk: a meta-analysis. PMID:28159929
LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy. PMID:28151474
Discovery of Cancer Driver Long Noncoding RNAs across 1112 Tumour Genomes: New Candidates and Distinguishing Features. PMID:28128360
Immunobiology of Long Noncoding RNAs. PMID:28125358
The long non-coding RNA NKILA inhibits the invasion-metastasis cascade of malignant melanoma via the regulation of NF-ĸB. PMID:28123845
Integrated Analysis of Long Non-coding RNAs (LncRNAs) and mRNA Expression Profiles Reveals the Potential Role of LncRNAs in Skeletal Muscle Development of the Chicken. PMID:28119630
Co-expression network analysis of long noncoding RNAs (IncRNAs) and cancer genes revealsSFTA1P and CASC2abnormalities in lung squamous cell carcinoma. PMID:28118064
Lncident: A Tool for Rapid Identification of Long Noncoding RNAs Utilizing Sequence Intrinsic Composition and Open Reading Frame Information. PMID:28116287
The Long Noncoding RNA Landscape of the Ischemic Human Left Ventricle. PMID:28115490
Transposable elements (TEs) contribute to stress-related long intergenic noncoding RNAs in plants. PMID:28106309
The systematic analysis of coding and long non-coding RNAs in the sub-chronic and chronic stages of spinal cord injury. PMID:28106101
Long non-coding RNAs in osteosarcoma. PMID:28103585
Massive Effect on LncRNAs in Human Monocytes During Fungal and Bacterial Infections and in Response to Vitamins A and D. PMID:28094339
Intersections of post-transcriptional gene regulatory mechanisms with intermediary metabolism. PMID:28088440
Long non-coding RNA exchange during the oocyte-to-embryo transition in mice. PMID:28087610
The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling. PMID:28086904
KTCNlncDB-a first platform to investigate lncRNAs expressed in human keratoconus and non-keratoconus corneas. PMID:28077570
MALAT1 promoted invasiveness of gastric adenocarcinoma. PMID:28077118
Long noncoding RNA repertoire in chicken liver and adipose tissue. PMID:28073357
Genome-Wide DNA Methylation Patterns Analysis of Noncoding RNAs in Temporal Lobe Epilepsy Patients. PMID:28058582
The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states. PMID:28054653
Functional RNA classes: a matter of time? PMID:28054565
FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome. PMID:28053114
Global Prioritizing Disease Candidate lncRNAs via a Multi-level Composite Network. PMID:28051121
MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus. PMID:28049826
Comparative analysis of DNA methylome and transcriptome of skeletal muscle in lean-, obese-, and mini-type pigs. PMID:28045116
Long Noncoding RNA Identification: Comparing Machine Learning Based Tools for Long Noncoding Transcripts Discrimination. PMID:28042575
Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks. PMID:28041957
lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1/Suz12 Complex in the CNS. PMID:28041882
The role of long non-coding RNAs in nasopharyngeal carcinoma: As systemic review. PMID:28039476
Transcriptional Gene Silencing of the Autism-Associated Long Noncoding RNA MSNP1AS in Human Neural Progenitor Cells. PMID:28030860
Noncoding RNA Profiles in Tobacco- and Alcohol-Associated Diseases. PMID:28025544
mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. PMID:28024296
Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs. PMID:28017589
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization. PMID:28004750
Primate-specific oestrogen-responsive long non-coding RNAs regulate proliferation and viability of human breast cancer cells. PMID:28003470
Quantitative approaches for investigating the spatial context of gene expression. PMID:28001340
Role of lncRNAs in Cellular Aging. PMID:27999563
Identification of cancer risk lncRNAs and cancer risk pathways regulated by cancer risk lncRNAs based on genome sequencing data in human cancers. PMID:27991568
Alternative splicing of the OCC-1 gene generates three splice variants and a novel exonic microRNA, which regulate the Wnt signaling pathway. PMID:27986894
Integrating Epigenomics into the Understanding of Biomedical Insight. PMID:27980397
Large-scale mapping of mammalian transcriptomes identifies conserved genes associated with different cell states. PMID:27980097
Long intragenic non-coding RNA lincRNA-p21 suppresses development of human prostate cancer. PMID:27976428
Construction of differential mRNA-lncRNA crosstalk networks based on ceRNA hypothesis uncover key roles of lncRNAs implicated in esophageal squamous cell carcinoma. PMID:27966444
Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx. PMID:27964752
LncRNAs expression profiling in normal ovary, benign ovarian cyst and malignant epithelial ovarian cancer. PMID:27941916
Expression profiling and functional annotation of noncoding genes across 11 distinct organs in rat development. PMID:27934932
Screening of long non-coding RNA and TUG1 inhibits proliferation with TGF-β induction in patients with COPD. PMID:27932875
The Long Noncoding RNA Transcriptome of Dictyostelium discoideum Development. PMID:27932387
Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs. PMID:27927715
FARNA: knowledgebase of inferred functions of non-coding RNA transcripts. PMID:27924038
Identification and functional analysis of long intergenic noncoding RNA genes in porcine pre-implantation embryonic development. PMID:27922056
HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cells. PMID:27920576
Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System. PMID:27913643
Novel brain expressed RNA identified at the MIR137 schizophrenia-associated locus. PMID:27913161
LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56. PMID:27912097
Expression and clinicopathological significance of the lncRNA HOXA11-AS in colorectal cancer. PMID:27895785
The emerging role of long non-coding RNA in gallbladder cancer pathogenesis. PMID:27894946
Regulatory non-coding RNAs in acute myocardial infarction. PMID:27878945
Integrative classification of human coding and noncoding genes through RNA metabolism profiles. PMID:27870833
TACO produces robust multisample transcriptome assemblies from RNA-seq. PMID:27869815
Differential expression and emerging functions of non-coding RNAs in cold adaptation. PMID:27866230
The pleiotropic role of non-coding genes in development and cancer. PMID:27865128
Long Non-Coding RNAs: A Novel Paradigm for Toxicology. PMID:27864543
lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis. PMID:27859817
AnnoLnc: a web server for systematically annotating novel human lncRNAs. PMID:27852242
LncRNA as a Therapeutic Target for Angiogenesis. PMID:27848894
The prognostic value of long non coding RNAs in non small cell lung cancer: A meta-analysis. PMID:27833074
A Comprehensive Characterization of the Function of LincRNAs in Transcriptional Regulation Through Long-Range Chromatin Interactions. PMID:27824113
Metastasis-associated long noncoding RNAs in gastrointestinal cancer: Implications for novel biomarkers and therapeutic targets. PMID:27818589
Update on the genetic architecture of rheumatoid arthritis. PMID:27811914
Transcriptome analysis of distinct long non-coding RNA transcriptional fingerprints in lung adenocarcinoma and squamous cell carcinoma. PMID:27797003
Upregulation of LncRNA-HIT promotes migration and invasion of non-small cell lung cancer cells by association with ZEB1. PMID:27790864
H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer. PMID:27789274
Differential expression of long non-coding RNAs in three genetic lines of rainbow trout in response to infection with Flavobacterium psychrophilum. PMID:27786264
Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay. PMID:27782208
Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression. PMID:27780979
The role and possible mechanism of lncRNA U90926 in modulating 3T3-L1 preadipocyte differentiation. PMID:27780975
Divergent lncRNAs take the lead on pluripotent cell differentiation. PMID:27777936
The state of play in higher eukaryote gene annotation. PMID:27773922
Microarray analysis on the lncRNA expression profile in male hepatocelluar carcinoma patients with chronic hepatitis B virus infection. PMID:27769059
LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL). PMID:27759039
Global and cell-type specific properties of lincRNAs with ribosome occupancy. PMID:27738133
Computational identification of putative lincRNAs in mouse embryonic stem cell. PMID:27713513
A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer. PMID:27713484
Knockdown of Long Noncoding RNA uc.338 by siRNA Inhibits Cellular Migration and Invasion in Human Lung Cancer Cells. PMID:27712590
lncScore: alignment-free identification of long noncoding RNA from assembled novel transcripts. PMID:27708423
Development of a RNA-Seq Based Prognostic Signature in Lung Adenocarcinoma. PMID:27707839
P2X7 receptors in body temperature, locomotor activity, and brain mRNA and lncRNA responses to sleep deprivation. PMID:27707719
DIGIT Is a Conserved Long Noncoding RNA that Regulates GSC Expression to Control Definitive Endoderm Differentiation of Embryonic Stem Cells. PMID:27705785
Insights from lncRNAs Profiling of MIN6 Beta Cells Undergoing Inflammation. PMID:27698546
Applications of Extracellular RNAs in Oncology. PMID:27688207
Consensus Analysis of Whole Transcriptome Profiles from Two Breast Cancer Patient Cohorts Reveals Long Non-Coding RNAs Associated with Intrinsic Subtype and the Tumour Microenvironment. PMID:27685983
Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration. PMID:27681436
Long noncoding RNA (lincRNA), a new paradigm in gene expression control. PMID:27681237
Long non-coding RNAs in the regulation of myeloid cells. PMID:27680332
A generative model for the behavior of RNA polymerase. PMID:27663494
Systematically characterizing dysfunctional long intergenic non-coding RNAs in multiple brain regions of major psychosis. PMID:27661005
Genome-wide long non-coding RNA screening, identification and characterization in a model microorganism Chlamydomonas reinhardtii. PMID:27659799
LNCediting: a database for functional effects of RNA editing in lncRNAs. PMID:27651464
Long non-coding RNA H19 enhances cell proliferation and anchorage-independent growth of cervical cancer cell lines. PMID:27633578
A critical overview of long non-coding RNA in glioma etiology 2016: an update. PMID:27629290
Genome-wide analysis of long intergenic non-coding RNAs in chickpea and their potential role in flower development. PMID:27628568
The Tetraodon nigroviridis reference transcriptome: developmental transition, length retention and microsynteny of long non-coding RNAs in a compact vertebrate genome. PMID:27628538
Knockdown of Long Noncoding RNA NR_026689 Inhibits Proliferation and Invasion and Increases Apoptosis in Ovarian Carcinoma HO-8910PM Cells. PMID:27624216
Long noncoding RNAs are novel potential prognostic biomarkers for esophageal squamous cell carcinoma: an overview. PMID:27621894
Portraying breast cancers with long noncoding RNAs. PMID:27617288
Epigenomic and metabolic responses of hypothalamic POMC neurons to gestational nicotine exposure in adult offspring. PMID:27609221
COME: a robust coding potential calculation tool for lncRNA identification and characterization based on multiple features. PMID:27608726
Current Status of Long Non-Coding RNAs in Human Breast Cancer. PMID:27608009
Identification of candidate anti-cancer molecular mechanisms of Compound Kushen Injection using functional genomics. PMID:27602759
Fast genotyping of known SNPs through approximate k-mer matching. PMID:27587672
ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells. PMID:27582018
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1. PMID:27578251
Evolution to the rescue: using comparative genomics to understand long non-coding RNAs. PMID:27573374
Single-nucleus RNA-seq of differentiating human myoblasts reveals the extent of fate heterogeneity. PMID:27566152
A molecular conundrum involving hypothalamic responses to and roles of long non-coding RNAs following food deprivation. PMID:27555291
Intron gain by tandem genomic duplication: a novel case in a potato gene encoding RNA-dependent RNA polymerase. PMID:27547574
Noncoding RNAs in gastric cancer: Research progress and prospects. PMID:27547004
lncRNA expression in the auditory forebrain during postnatal development. PMID:27544636
Mouse models of Down syndrome: gene content and consequences. PMID:27538963
Extension of human lncRNA transcripts by RACE coupled with long-read high-throughput sequencing (RACE-Seq). PMID:27531712
Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial. PMID:27527847
Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer. PMID:27526323
IRWRLDA: improved random walk with restart for lncRNA-disease association prediction. PMID:27517318
Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma. PMID:27517149
Long noncoding RNAs in hematopoiesis. PMID:27508063
Brain enhancer activities at the gene-poor 5p14.1 autism-associated locus. PMID:27503586
Functions and mechanisms of long noncoding RNAs in lung cancer. PMID:27499635
Functional prediction of differentially expressed lncRNAs in HSV-1 infected human foreskin fibroblasts. PMID:27496175
Downregulation of the long noncoding RNA GAS5-AS1 contributes to tumor metastasis in non-small cell lung cancer. PMID:27489122
Systematic Analysis of Long Noncoding RNAs in the Senescence-accelerated Mouse Prone 8 Brain Using RNA Sequencing. PMID:27483026
Investigating long noncoding RNAs using animal models. PMID:27479747
End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data. PMID:27470110
Stress-induced and epigenetic-mediated maize transcriptome regulation study by means of transcriptome reannotation and differential expression analysis. PMID:27461139
Secondary structure impacts patterns of selection in human lncRNAs. PMID:27457204
LncRNAs and cancer. PMID:27446422
Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin. PMID:27443263
A Genomic Analysis of Factors Driving lincRNA Diversification: Lessons from Plants. PMID:27440919
RNA polymerase II promoter-proximal pausing in mammalian long non-coding genes. PMID:27432546
Prospective and therapeutic screening value of non-coding RNA as biomarkers in cardiovascular disease. PMID:27429962
Unraveling the oral cancer lncRNAome: Identification of novel lncRNAs associated with malignant progression and HPV infection. PMID:27424183
Long noncoding RNAs and Alzheimer's disease. PMID:27418812
Developmentally regulated long non-coding RNAs in Xenopus tropicalis. PMID:27418388
Long Noncoding RNA and mRNA Expression Profiles in the Thyroid Gland of Two Phenotypically Extreme Pig Breeds Using Ribo-Zero RNA Sequencing. PMID:27409639
CTRL+INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome. PMID:27402545
Long non-coding RNAs are major contributors to transcriptome changes in sunflower meiocytes with different recombination rates. PMID:27401977
Long Non-coding RNAs and Their Roles in Non-small-cell Lung Cancer. PMID:27397102
SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism. PMID:27396952
Inflammation and epigenetic regulation in osteoarthritis. PMID:27389927
Genome Wide Identification and Functional Prediction of Long Non-Coding RNAs Responsive to Sclerotinia sclerotiorum Infection in Brassica napus. PMID:27388760
Long noncoding RNAs in B-cell development and activation. PMID:27381906
Noncoding RNAs in the regulation of skeletal muscle biology in health and disease. PMID:27377406
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. PMID:27376578
Extensive ceRNA-ceRNA interaction networks mediated by miRNAs regulate development in multiple rhesus tissues. PMID:27365046
Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine. PMID:27363492
Circulating biomarkers to monitor cancer progression and treatment. PMID:27358717
Long non-coding RNAs and complex diseases: from experimental results to computational models. PMID:27345524
Cancer subtypes classification using long non-coding RNA. PMID:27340923
Long non-coding RNA-mediated regulation of glucose homeostasis and diabetes. PMID:27335687
Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome. PMID:27333023
Significant association between long non-coding RNA HOTAIR polymorphisms and cancer susceptibility: a meta-analysis. PMID:27330313
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq. PMID:27329541
Downregulation of the long noncoding RNA TUG1 inhibits the proliferation, migration, invasion and promotes apoptosis of renal cell carcinoma. PMID:27323757
Diagnostic Potential of lncRNAs in Cancer. PMID:27322445
Identification of long non-coding RNAs involved in neuronal development and intellectual disability. PMID:27319317
LncRNA-MIF, a c-Myc-activated long non-coding RNA, suppresses glycolysis by promoting Fbxw7-mediated c-Myc degradation. PMID:27317567
A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. PMID:27315481
Effects of Guchang Capsule on Dextran Sulphate Sodium-Induced Experimental Ulcerative Colitis in Mice. PMID:27313642
Long noncoding RNAs in prostate cancer: mechanisms and applications. PMID:27308347
Genome-Wide Analysis of Long Noncoding RNAs and Their Responses to Drought Stress in Cotton (Gossypium hirsutum L.). PMID:27294517
Genome-wide interrogation reveals hundreds of long intergenic noncoding RNAs that associate with cardiometabolic traits. PMID:27288454
Hepatitis B virus genotypes, expression quantitative trait loci for ZNRD1-AS1 and their interactions in hepatocellular carcinoma. PMID:27286450
Noncoding RNA joins Ku and DNA-PKcs for DNA-break resistance in breast cancer. PMID:27273637
Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo. PMID:27265476
A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA. PMID:27263970
Emerging roles for long noncoding RNAs in skeletal biology and disease. PMID:27254479
Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine. PMID:27251103
Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer. PMID:27250026
Transcriptome profiling of patient derived xenograft models established from pediatric acute myeloid leukemia patients confirm maintenance of FLT3-ITD mutation. PMID:27248844
Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression. PMID:27246976
Lessons from non-canonical splicing. PMID:27240813
Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children. PMID:27236921
Environmental Health and Long Non-coding RNAs. PMID:27234044
Long non-coding RNA: Functional agent for disease traits. PMID:27229269
LncRNApred: Classification of Long Non-Coding RNAs and Protein-Coding Transcripts by the Ensemble Algorithm with a New Hybrid Feature. PMID:27228152
The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation. PMID:27226347
Noncoding RNAs in human cancer: one step forward in diagnosis and treatment. PMID:27226104
Review: Long Noncoding RNAs in the Regulation of Inflammatory Pathways in Rheumatoid Arthritis and Osteoarthritis. PMID:27214788
Improved definition of the mouse transcriptome via targeted RNA sequencing. PMID:27197243
Understanding the Functions of Long Non-Coding RNAs through Their Higher-Order Structures. PMID:27196897
Comparative Expression Dynamics of Intergenic Long Noncoding RNAs in the Genus Drosophila. PMID:27189981
Exosomal Long Noncoding RNAs are Differentially Expressed in the Cervicovaginal Lavage Samples of Cervical Cancer Patients. PMID:27184657
Evaluation of the Role of Circulating Long Non-Coding RNA H19 as a Promising Novel Biomarker in Plasma of Patients with Gastric Cancer. PMID:27184562
An updated human snoRNAome. PMID:27174936
Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer. PMID:27172249
Long Non-coding RNAs in the Cytoplasm. PMID:27163185
Dissecting the expression relationships between RNA-binding proteins and their cognate targets in eukaryotic post-transcriptional regulatory networks. PMID:27161996
Diverse regulatory interactions of long noncoding RNAs. PMID:27151434
Long Non-Coding RNAs As Potential Novel Prognostic Biomarkers in Colorectal Cancer. PMID:27148353
NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548. PMID:27147820
Integrative analysis reveals clinical phenotypes and oncogenic potentials of long non-coding RNAs across 15 cancer types. PMID:27147563
PU.1 controls the expression of long noncoding RNA HOTAIRM1 during granulocytic differentiation. PMID:27146823
cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth. PMID:27140397
A long non-coding RNA, APOA4-AS, regulates APOA4 expression depending on HuR in mice. PMID:27131369
The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation. PMID:27129154
Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. PMID:27111890
Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality. PMID:27095194
Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells. PMID:27090285
Epigenetic regulation of bone cells. PMID:27082893
RNA Directed Modulation of Phenotypic Plasticity in Human Cells. PMID:27082860
The interplay of long non-coding RNAs and MYC in cancer. PMID:27077133
Long noncoding RNAs in prostate cancer: overview and clinical implications. PMID:27072044
Long Noncoding RNAs in Cancer Pathways. PMID:27070700
Impacts of Salmonella enterica Serovar Typhimurium and Its speG Gene on the Transcriptomes of In Vitro M Cells and Caco-2 Cells. PMID:27064787
Transcriptional gene silencing in humans. PMID:27060137
LINC00507 Is Specifically Expressed in the Primate Cortex and Has Age-Dependent Expression Patterns. PMID:27059230
Long non-coding RNA Databases in Cardiovascular Research. PMID:27049585
Small and Long Non-Coding RNAs: Novel Targets in Perspective Cancer Therapy. PMID:27047252
Retrotransposon-associated long non-coding RNAs in mice and men. PMID:27044413
Increased expression of the long noncoding RNA CRNDE-h indicates a poor prognosis in colorectal cancer, and is positively correlated with IRX5 mRNA expression. PMID:27042112
Endogenous microRNA sponges: evidence and controversy. PMID:27040487
A long noncoding RNA associated with susceptibility to celiac disease. PMID:27034373
The Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans. PMID:27032491
Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer. PMID:27027352
Altered Long Noncoding RNA Expression Precedes the Course of Parkinson's Disease-a Preliminary Report. PMID:27021022
Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma. PMID:27013343
Adipose tissue RNASeq reveals novel gene-nutrient interactions following n-3 PUFA supplementation and evoked inflammation in humans. PMID:27012629
Function and evolution of local repeats in the Firre locus. PMID:27009974
Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins. PMID:27007663
Mechanisms of long noncoding RNA function in development and disease. PMID:27007508
Distinct temporal changes in host cell lncRNA expression during the course of an adenovirus infection. PMID:27003248
Spatial Organization of Epigenomes. PMID:26986719
Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer. PMID:26975529
Long noncoding RNAs in psychiatric disorders. PMID:26974119
Long Non-coding RNA in Neurons: New Players in Early Response to BDNF Stimulation. PMID:26973456
Integrating RNA-seq and ChIP-seq data to characterize long non-coding RNAs in Drosophila melanogaster. PMID:26969372
Comparative analysis of human and mouse transcriptomes of Th17 cell priming. PMID:26967054
Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity. PMID:26965636
Enhancers as non-coding RNA transcription units: recent insights and future perspectives. PMID:26948815
Non-coding RNA LINC00473 mediates decidualization of human endometrial stromal cells in response to cAMP signaling. PMID:26947914
Roles for long non-coding RNAs in physiology and disease. PMID:26944276
Identification and characterization of lncRNA mediated transcriptional dysregulation dictates lncRNA roles in glioblastoma. PMID:26943771
Genome-Wide Identification and Characterization of Long Non-Coding RNAs from Mulberry (Morus notabilis) RNA-seq Data. PMID:26938562
PRINS, a primate-specific long non-coding RNA, plays a role in the keratinocyte stress response and psoriasis pathogenesis. PMID:26935426
Long noncoding RNAs in gastric cancer: functions and clinical applications. PMID:26929639
Comprehensive analysis of lncRNA expression profiles and identification of functional lncRNAs in lung adenocarcinoma. PMID:26918601
Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57. PMID:26913601
Genome and transcriptome analysis of the Mesoamerican common bean and the role of gene duplications in establishing tissue and temporal specialization of genes. PMID:26911872
The Role of Long Noncoding RNAs in Neurodegenerative Diseases. PMID:26910817
lncRNA/MicroRNA interactions in the vasculature. PMID:26910520
Genome-Wide Discovery of Long Non-Coding RNAs in Rainbow Trout. PMID:26895175
Downregulation of BC200 in ovarian cancer contributes to cancer cell proliferation and chemoresistance to carboplatin. PMID:26893717
From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease. PMID:26892960
Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing. PMID:26887054
Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer. PMID:26883671
Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression. PMID:26876208
Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR-148a-3p/DNMT1 axis. PMID:26872375
Enhancer RNA-driven looping enhances the transcription of the long noncoding RNA DHRS4-AS1, a controller of the DHRS4 gene cluster. PMID:26864944
Identification and Functional Prediction of Large Intergenic Noncoding RNAs (lincRNAs) in Rainbow Trout (Oncorhynchus mykiss). PMID:26864089
Inter-Individual Differences in RNA Levels in Human Peripheral Blood. PMID:26863434
Down-Regulatory Effects of miR-211 on Long Non-Coding RNA SOX2OT and SOX2 Genes in Esophageal Squamous Cell Carcinoma. PMID:26862518
Long-noncoding RNAs in basal cell carcinoma. PMID:26861560
Functional analysis of long intergenic non-coding RNAs in phosphate-starved rice using competing endogenous RNA network. PMID:26860696
A Simple Test of Class-Level Genetic Association Can Reveal Novel Cardiometabolic Trait Loci. PMID:26859766
Biochemical Methods To Investigate lncRNA and the Influence of lncRNA:Protein Complexes on Chromatin. PMID:26859437
Long non-coding RNA LINC01133 represses KLF2, P21 and E-cadherin transcription through binding with EZH2, LSD1 in non small cell lung cancer. PMID:26840083
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs. PMID:26838501
Biological Processes Discovered by High-Throughput Sequencing. PMID:26828742
Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans. PMID:26821746
LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR. PMID:26819413
Comprehensive prediction of lncRNA-RNA interactions in human transcriptome. PMID:26818453
Transcriptional profiling analysis and functional prediction of long noncoding RNAs in cancer. PMID:26812883
Emerging roles of non-coding RNAs in gastric cancer: Pathogenesis and clinical implications. PMID:26811659
Epigenetic regulation of early neural fate commitment. PMID:26801220
Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes. PMID:26800519
Overexpression of long non-coding RNA LOC400891 promotes tumor progression and poor prognosis in prostate cancer. PMID:26797783
Long noncoding RNAs: new insights into non-small cell lung cancer biology, diagnosis and therapy. PMID:26786153
Genome-wide analysis of long non-coding RNAs at early stage of skin pigmentation in goats (Capra hircus). PMID:26785828
Rapid evolutionary turnover underlies conserved lncRNA-genome interactions. PMID:26773003
Diverse Hormone Response Networks in 41 Independent Drosophila Cell Lines. PMID:26772746
Systematic Identification and Characterization of Long Non-Coding RNAs in the Silkworm, Bombyx mori. PMID:26771876
Identifying and functionally characterizing tissue-specific and ubiquitously expressed human lncRNAs. PMID:26760768
CANEapp: a user-friendly application for automated next generation transcriptomic data analysis. PMID:26758513
Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. PMID:26757825
Age-Related Expression of a Repeat-Rich Intergenic Long Noncoding RNA in the Rat Brain. PMID:26750132
Altered long non-coding RNA transcriptomic profiles in brain microvascular endothelium after cerebral ischemia. PMID:26746985
Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons. PMID:26738766
Uncovering the roles of long noncoding RNAs in neural development and glioma progression. PMID:26733304
In Silico Functional Annotation of Genomic Variation. PMID:26724722
A novel long noncoding RNA IRAIN regulates cell proliferation in non small cell lung cancer. PMID:26722412
Detection of Long Noncoding RNA Expression by Nonradioactive Northern Blots. PMID:26721491
Characterization of Long Noncoding RNA-Associated Proteins by RNA-Immunoprecipitation. PMID:26721480
Identification of important long non-coding RNAs and highly recurrent aberrant alternative splicing events in hepatocellular carcinoma through integrative analysis of multiple RNA-Seq datasets. PMID:26711644
Chromatin and RNA Maps Reveal Regulatory Long Noncoding RNAs in Mouse. PMID:26711262
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. PMID:26701265
Long Noncoding RNA Regulation of Pluripotency. PMID:26697072
Decreased long noncoding RNA MIR31HG is correlated with poor prognosis and contributes to cell proliferation in gastric cancer. PMID:26692098
LncRNAs: emerging players in gene regulation and disease pathogenesis. PMID:26690535
Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism. PMID:26690121
A novel long non-coding RNA in the rheumatoid arthritis risk locus TRAF1-C5 influences C5 mRNA levels. PMID:26673966
Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors. PMID:26673794
A human haploid gene trap collection to study lncRNAs with unusual RNA biology. PMID:26670263
lncRNAs regulate the innate immune response to viral infection. PMID:26667656
Unique features of long non-coding RNA biogenesis and function. PMID:26666209
Pseudogene-expressed RNAs: a new frontier in cancers. PMID:26662308
Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1. PMID:26658965
The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAs. PMID:26654912
A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers. PMID:26646903
Targeting Non-Coding RNAs in Plants with the CRISPR-Cas Technology is a Challenge yet Worth Accepting. PMID:26635829
The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers. PMID:26634743
Short-Circuiting Gene Regulatory Networks: Origins of B Cell Lymphoma. PMID:26604030
The primate-specific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming. PMID:26595768
Identification of global regulators of T-helper cell lineage specification. PMID:26589177
NONCODE 2016: an informative and valuable data source of long non-coding RNAs. PMID:26586799
Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides. PMID:26578588
Transcriptome-wide functional characterization reveals novel relationships among differentially expressed transcripts in developing soybean embryos. PMID:26572793
All-Trans Retinoic Acid Induces Expression of a Novel Intergenic Long Noncoding RNA in Adult rat Primary Hippocampal Neurons. PMID:26572536
Noncoding RNA in the transcriptional landscape of human neural progenitor cell differentiation. PMID:26557050
A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients. PMID:26549855
Transposable elements at the center of the crossroads between embryogenesis, embryonic stem cells, reprogramming, and long non-coding RNAs. PMID:26543668
Downregulation of miR-320a/383-sponge-like long non-coding RNA NLC1-C (narcolepsy candidate-region 1 genes) is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation. PMID:26539909
Long noncoding RNAs in T lymphocytes. PMID:26538526
Towards structural classification of long non-coding RNAs. PMID:26537437
Long non-coding RNA regulation of reproduction and development. PMID:26517592
The Clinical Relevance of Long Non-Coding RNAs in Cancer. PMID:26516918
Long non-coding RNAs in corticogenesis: deciphering the non-coding code of the brain. PMID:26516210
Decoding the non-coding genome: elucidating genetic risk outside the coding genome. PMID:26515765
Functional genomics of human brain development and implications for autism spectrum disorders. PMID:26506051
Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages. PMID:26502406
Unveiling the hidden function of long non-coding RNA by identifying its major partner-protein. PMID:26500759
A catalogue of novel bovine long noncoding RNA across 18 tissues. PMID:26496443
DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs. PMID:26493208
Epigenetics mechanisms in renal development. PMID:26493068
LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns. PMID:26485761
Whole transcriptome RNA sequencing data from blood leukocytes derived from Parkinson's disease patients prior to and following deep brain stimulation treatment. PMID:26484149
Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells. PMID:26480000
Complexity of a small non-protein coding sequence in chromosomal region 22q11.2: presence of specialized DNA secondary structures and RNA exon/intron motifs. PMID:26467088
Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis. PMID:26461935
LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. PMID:26461224
Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers. PMID:26461095
Hepatic Long Intergenic Noncoding RNAs: High Promoter Conservation and Dynamic, Sex-Dependent Transcriptional Regulation by Growth Hormone. PMID:26459762
MicroRNA-Specificity Protein (Sp) Transcription Factor Interactions and Significance in Carcinogenesis. PMID:26457240
Functional Analyses of Transcription Factor Binding Sites that Differ between Present-Day and Archaic Humans. PMID:26454764
Long noncoding RNAs in viral infections. PMID:26454188
De novo transcriptome profiling of highly purified human lymphocytes primary cells. PMID:26451251
CircNet: a database of circular RNAs derived from transcriptome sequencing data. PMID:26450965
Genome-wide identification of long noncoding RNA genes and their potential association with fecundity and virulence in rice brown planthopper, Nilaparvata lugens. PMID:26437919
lncRScan-SVM: A Tool for Predicting Long Non-Coding RNAs Using Support Vector Machine. PMID:26437338
Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations. PMID:26431491
A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer. PMID:26430965
Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer. PMID:26426411
Epigenetic silencing of a long non-coding RNA KIAA0495 in multiple myeloma. PMID:26410378
Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape. PMID:26408185
The long noncoding RNA landscape in hypoxic and inflammatory renal epithelial injury. PMID:26400545
Evolutionary impact of transposable elements on genomic diversity and lineage-specific innovation in vertebrates. PMID:26395902
Long Noncoding RNA Expression during Human B-Cell Development. PMID:26394393
Whole-Genome Sequencing Suggests Schizophrenia Risk Mechanisms in Humans with 22q11.2 Deletion Syndrome. PMID:26384369
Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR. PMID:26379229
Extensive identification and analysis of conserved small ORFs in animals. PMID:26364619
Co-LncRNA: investigating the lncRNA combinatorial effects in GO annotations and KEGG pathways based on human RNA-Seq data. PMID:26363020
Lung endoderm morphogenesis: gasping for form and function. PMID:26359777
MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells. PMID:26351698
Urothelial cancer associated 1: a long noncoding RNA with a crucial role in cancer. PMID:26341664
Genome-wide characterization of long intergenic non-coding RNAs (lincRNAs) provides new insight into viral diseases in honey bees Apis cerana and Apis mellifera. PMID:26341079
IDH1 mutation-associated long non-coding RNA expression profile changes in glioma. PMID:26337623
Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2. PMID:26336870
Architectural and Functional Commonalities between Enhancers and Promoters. PMID:26317464
DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer. PMID:26307088
Construction and analysis of lncRNA-lncRNA synergistic networks to reveal clinically relevant lncRNAs in cancer. PMID:26305674
Evolution of the unspliced transcriptome. PMID:26289325
MicroRNAs and Noncoding RNAs in Hepatic Lipid and Lipoprotein Metabolism: Potential Therapeutic Targets of Metabolic Disorders. PMID:26286650
An Association Rule Mining Approach to Discover lncRNAs Expression Patterns in Cancer Datasets. PMID:26273587
Assessing Recent Selection and Functionality at Long Noncoding RNA Loci in the Mouse Genome. PMID:26272717
Long non-coding RNAs era in liver cancer. PMID:26261686
SINEUPs: A new class of natural and synthetic antisense long non-coding RNAs that activate translation. PMID:26259533
Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases. PMID:26258142
Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes. PMID:26257179
Gene expression patterns in CD4+ peripheral blood cells in healthy subjects and stage IV melanoma patients. PMID:26245876
Discovery, Annotation, and Functional Analysis of Long Noncoding RNAs Controlling Cell-Cycle Gene Expression and Proliferation in Breast Cancer Cells. PMID:26236012
Long Non-Coding RNAs: The Key Players in Glioma Pathogenesis. PMID:26230711
Identification of long noncoding RNAs dysregulated in the midbrain of human cocaine abusers. PMID:26222413
Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers. PMID:26216839
Database of RNA binding protein expression and disease dynamics (READ DB). PMID:26210853
Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration. PMID:26207833
Creating reference gene annotation for the mouse C57BL6/J genome assembly. PMID:26187010
Cutting Edge: A Natural Antisense Transcript, AS-IL1α, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1α. PMID:26179904
Genome-Wide Reprogramming of Transcript Architecture by Temperature Specifies the Developmental States of the Human Pathogen Histoplasma. PMID:26177267
Long non-coding RNA and chromatin remodeling. PMID:26177256
Long non-coding RNAs in innate and adaptive immunity. PMID:26166759
Differential and coherent processing patterns from small RNAs. PMID:26166713
Genome-scale long noncoding RNA expression pattern in squamous cell lung cancer. PMID:26159226
Global analysis of biogenesis, stability and sub-cellular localization of lncRNAs mapping to intragenic regions of the human genome. PMID:26151857
Microarray profiling of long non-coding RNA (lncRNA) associated with hypertrophic cardiomyopathy. PMID:26141701
Long noncoding RNAs in diseases of aging. PMID:26141605
Neurodevelopmental LincRNA Microsyteny Conservation and Mammalian Brain Size Evolution. PMID:26134977
Transposable Element Insertions in Long Intergenic Non-Coding RNA Genes. PMID:26106594
Dysregulated transcription across diverse cancer types reveals the importance of RNA-binding protein in carcinogenesis. PMID:26100984
Analysis of intronic and exonic reads in RNA-seq data characterizes transcriptional and post-transcriptional regulation. PMID:26098447
Epigenetics in NG2 glia cells. PMID:26092401
Computational Approaches for the Analysis of ncRNA through Deep Sequencing Techniques. PMID:26090362
Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets. PMID:26082843
MBRidge: an accurate and cost-effective method for profiling DNA methylome at single-base resolution. PMID:26078362
Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex. PMID:26076492
Long noncoding RNAs: Re-writing dogmas of RNA processing and stability. PMID:26073320
Advances in long noncoding RNAs: identification, structure prediction and function annotation. PMID:26072035
Native Purification and Analysis of Long RNAs. PMID:26068736
zflncRNApedia: A Comprehensive Online Resource for Zebrafish Long Non-Coding RNAs. PMID:26065909
Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity. PMID:26061969
Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer. PMID:26055877
Identification and characterization of long non-coding RNAs involved in osmotic and salt stress in Medicago truncatula using genome-wide high-throughput sequencing. PMID:26048392
Regulation of the ESC transcriptome by nuclear long noncoding RNAs. PMID:26048247
Polymorphism Analysis Reveals Reduced Negative Selection and Elevated Rate of Insertions and Deletions in Intrinsically Disordered Protein Regions. PMID:26047845
Septic Shock in Advanced Age: Transcriptome Analysis Reveals Altered Molecular Signatures in Neutrophil Granulocytes. PMID:26047321
Emerging applications of read profiles towards the functional annotation of the genome. PMID:26042150
Revealing protein-lncRNA interaction. PMID:26041786
Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing. PMID:26040699
Involvement of long non-coding RNAs in beta cell failure at the onset of type 1 diabetes in NOD mice. PMID:26037202
SINEUPs are modular antisense long non-coding RNAs that increase synthesis of target proteins in cells. PMID:26029048
The code of non-coding RNAs in lung fibrosis. PMID:26026420
Basic biology and therapeutic implications of lncRNA. PMID:26024979
RNA biomarkers to facilitate the identification of aggressive prostate cancer. PMID:26022941
The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching. PMID:26016895
De novo transcriptome characterization and gene expression profiling of the desiccation tolerant moss Bryum argenteum following rehydration. PMID:26016800
LncRNA BCAR4 wires up signaling transduction in breast cancer. PMID:26016563
Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology. PMID:26013764
Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR. PMID:26000843
Comparative transcriptomic analysis of multiple cardiovascular fates from embryonic stem cells predicts novel regulators in human cardiogenesis. PMID:25997157
Transcriptomic landscape of lncRNAs in inflammatory bowel disease. PMID:25991924
Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events. PMID:25985263
GermlncRNA: a unique catalogue of long non-coding RNAs and associated regulations in male germ cell development. PMID:25982314
Dynamic and Widespread lncRNA Expression in a Sponge and the Origin of Animal Complexity. PMID:25976353
The role of long non-coding RNAs in genome formatting and expression. PMID:25972893
Principles of long noncoding RNA evolution derived from direct comparison of transcriptomes in 17 species. PMID:25959816
Long noncoding RNAs: a potential novel class of cancer biomarkers. PMID:25954300
Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation. PMID:25926836
Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs. PMID:25909911
A novel long noncoding RNA LINC01133 is upregulated in lung squamous cell cancer and predicts survival. PMID:25908174
A FOXM1 related long non-coding RNA contributes to gastric cancer cell migration. PMID:25907137
Expression and functions of long noncoding RNAs during human T helper cell differentiation. PMID:25903499
Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex. PMID:25903279
Invasion and metastasis-related long noncoding RNA expression profiles in hepatocellular carcinoma. PMID:25900874
Long non-coding RNA functions in lung cancer. PMID:25895460
Long non-coding RNA LINC01296 is a potential prognostic biomarker in patients with colorectal cancer. PMID:25894381
Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markers. PMID:25887545
Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response. PMID:25885578
Prediction of long noncoding RNA functions with co-expression network in esophageal squamous cell carcinoma. PMID:25885227
Methamphetamine induces alterations in the long non-coding RNAs expression profile in the nucleus accumbens of the mouse. PMID:25884509
Expression analysis of the long non-coding RNA antisense to Uchl1 (AS Uchl1) during dopaminergic cells' differentiation in vitro and in neurochemical models of Parkinson's disease. PMID:25883552
Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription. PMID:25881024
The Landscape of long noncoding RNA classification. PMID:25869999
HOTAIR forms an intricate and modular secondary structure. PMID:25866246
Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function. PMID:25864709
The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma. PMID:25863539
Epigenetic regulation in hepatocellular carcinoma requires long noncoding RNAs. PMID:25861629
Non-coding RNAs and HIV: viral manipulation of host dark matter to shape the cellular environment. PMID:25859257
Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project. PMID:25854118
Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma. PMID:25848750
Epigenetics of the failing heart. PMID:25847519
The lncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression. PMID:25843708
Long non-coding RNA expression profile in the kidneys of male, low birth weight rats exposed to maternal protein restriction at postnatal day 1 and day 10. PMID:25826617
Non-coding RNA: a new frontier in regulatory biology. PMID:25821635
Activation of an endogenous retrovirus-associated long non-coding RNA in human adenocarcinoma. PMID:25821520
Modeling the relationship of epigenetic modifications to transcription factor binding. PMID:25820421
Nonsense-mediated RNA decay--a switch and dial for regulating gene expression. PMID:25820233
Predicting the functions of long noncoding RNAs using RNA-seq based on Bayesian network. PMID:25815337
LncRNAs in vertebrates: advances and challenges. PMID:25812751
Long Non-Coding RNA Expression during Aging in the Human Subependymal Zone. PMID:25806019
Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer. PMID:25800746
Transcriptome analyses of adult mouse brain reveal enrichment of lncRNAs in specific brain regions and neuronal populations. PMID:25798087
Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells. PMID:25792609
RNA regulators of host immunity and pathogen adaptive responses in the oral cavity. PMID:25790757
The role of non-coding RNAs in the regulation of stem cells and progenitors in the normal mammary gland and in breast tumors. PMID:25774169
Long non-coding RNAs control hematopoietic stem cell function. PMID:25772072
Long noncoding RNA turnover. PMID:25769416
Designing optogenetically controlled RNA for regulating biological systems. PMID:25758022
Systematic identification and characterization of long intergenic non-coding RNAs in fetal porcine skeletal muscle development. PMID:25753296
Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. PMID:25751143
The long non-coding RNA PCGEM1 is regulated by androgen receptor activity in vivo. PMID:25744782
Genome-wide DNA methylome analysis reveals epigenetically dysregulated non-coding RNAs in human breast cancer. PMID:25739977
Prognostic impact of HOTAIR expression is restricted to ER-negative breast cancers. PMID:25739705
Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. PMID:25739401
A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice. PMID:25738460
Upregulation of the long noncoding RNA PCAT-1 correlates with advanced clinical stage and poor prognosis in esophageal squamous carcinoma. PMID:25731728
Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. PMID:25730776
The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins. PMID:25728138
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin. PMID:25723451
A survey of imprinted gene expression in mouse trophoblast stem cells. PMID:25711832
Pseudogene-derived lncRNAs: emerging regulators of gene expression. PMID:25699073
Large-scale imputation of epigenomic datasets for systematic annotation of diverse human tissues. PMID:25690853
Novel long non-coding RNAs are specific diagnostic and prognostic markers for prostate cancer. PMID:25686826
Non-coding RNA: what is functional and what is junk? PMID:25674102
Three-dimensional regulation of transcription. PMID:25670626
Expression and regulation of long noncoding RNAs in TLR4 signaling in mouse macrophages. PMID:25652569
The selection and function of cell type-specific enhancers. PMID:25650801
Noncoding RNA as therapeutic targets for hepatocellular carcinoma. PMID:25632936
Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution. PMID:25630241
The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. PMID:25621826
Junk DNA and the long non-coding RNA twist in cancer genetics. PMID:25619839
Post-transcriptional regulation of long noncoding RNAs in cancer. PMID:25618601
RPI-Pred: predicting ncRNA-protein interaction using sequence and structural information. PMID:25609700
Long ncRNA expression associates with tissue-specific enhancers. PMID:25607649
The landscape of long noncoding RNAs in the human transcriptome. PMID:25599403
Non-coding RNAs in lung cancer. PMID:25593996
Unexpected selection to retain high GC content and splicing enhancers within exons of multiexonic lncRNA loci. PMID:25589248
Genome wide chromatin occupancy of mrhl RNA and its role in gene regulation in mouse spermatogonial cells. PMID:25584904
Long non-coding RNAs in cancer and development: where do we go from here? PMID:25580533
A long non-coding RNA links calreticulin-mediated immunogenic cell removal to RB1 transcription. PMID:25579178
High expression of long intervening non-coding RNA OLMALINC in the human cortical white matter is associated with regulation of oligodendrocyte maturation. PMID:25575711
Functional Implications of RNA Splicing for Human Long Intergenic Noncoding RNAs. PMID:25574121
Discovery and annotation of long noncoding RNAs. PMID:25565026
Colon Cancer Associated Transcript-1 (CCAT1) Expression in Adenocarcinoma of the Stomach. PMID:25561974
Identification and computational analysis of gene regulatory elements. PMID:25561628
Long non-coding RNAs as regulators of the endocrine system. PMID:25560704
Epigenetic States of nephron progenitors and epithelial differentiation. PMID:25560433
Alternative RNA structure-coupled gene regulations in tumorigenesis. PMID:25551597
Long non-coding RNA normalisers in human brain tissue. PMID:25528156
Genome-wide screening and functional analysis identify a large number of long noncoding RNAs involved in the sexual reproduction of rice. PMID:25517485
Novel long noncoding RNAs (lncRNAs) in myogenesis: a miR-31 overlapping lncRNA transcript controls myoblast differentiation. PMID:25512605
Expression and prognostic impact of lncRNAs in acute myeloid leukemia. PMID:25512507
A common set of distinct features that characterize noncoding RNAs across multiple species. PMID:25505163
Characterization of novel transcripts of human papillomavirus type 16 using cap analysis gene expression technology. PMID:25505068
Developmental regulation of human cortex transcription and its clinical relevance at single base resolution. PMID:25501035
7SK small nuclear RNA inhibits cancer cell proliferation through apoptosis induction. PMID:25492483
Functions of lncRNA HOTAIR in lung cancer. PMID:25491133
Long noncoding RNAs: an emerging link between gene regulation and nuclear organization. PMID:25441720
Fine-scale chromatin interaction maps reveal the cis-regulatory landscape of human lincRNA genes. PMID:25437436
A pathophysiological view of the long non-coding RNA world. PMID:25428918
Identification of 4438 novel lincRNAs involved in mouse pre-implantation embryonic development. PMID:25428585
From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease. PMID:25426780
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc. PMID:25425964
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity. PMID:25419237
Comparison of the transcriptional landscapes between human and mouse tissues. PMID:25413365
A comparative encyclopedia of DNA elements in the mouse genome. PMID:25409824
De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics. PMID:25405465
Non-coding RNA derived from the region adjacent to the human HO-1 E2 enhancer selectively regulates HO-1 gene induction by modulating Pol II binding. PMID:25404134
MUNC, a long noncoding RNA that facilitates the function of MyoD in skeletal myogenesis. PMID:25403490
Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. PMID:25401475
Friends with social benefits: host-microbe interactions as a driver of brain evolution and development? PMID:25401092
Keeping abreast with long non-coding RNAs in mammary gland development and breast cancer. PMID:25400658
LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs. PMID:25399417
Co-expression Network Analysis of Human lncRNAs and Cancer Genes. PMID:25392693
Genome-wide identification of long noncoding RNAs in rat models of cardiovascular and renal disease. PMID:25385761
H19 long noncoding RNA controls the mRNA decay promoting function of KSRP. PMID:25385579
Small and Long Regulatory RNAs in the Immune System and Immune Diseases. PMID:25368617
The roles and regulation of Polycomb complexes in neural development. PMID:25367430
A high level of circulating HOTAIR is associated with progression and poor prognosis of cervical cancer. PMID:25366139
Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity. PMID:25359165
Proteogenomics: concepts, applications and computational strategies. PMID:25357241
RNAcentral: an international database of ncRNA sequences. PMID:25352543
Decoding neural transcriptomes and epigenomes via high-throughput sequencing. PMID:25349913
Regression analysis of combined gene expression regulation in acute myeloid leukemia. PMID:25340776
Sumoylation is Required for the Cytoplasmic Accumulation of a Subset of mRNAs. PMID:25333844
lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs. PMID:25332394
Gene-based rare allele analysis identified a risk gene of Alzheimer's disease. PMID:25329708
Genome-wide profiling of mouse RNA secondary structures reveals key features of the mammalian transcriptome. PMID:25323333
Databases for lncRNAs: a comparative evaluation of emerging tools. PMID:25323317
Regulation of lncRNA expression. PMID:25311814
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. PMID:25307932
Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications. PMID:25307233
Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7. PMID:25306109
Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2. PMID:25303483
The many faces of long noncoding RNAs. PMID:25303371
Circadian genomics reveal a role for post-transcriptional regulation in mammals. PMID:25303020
Long non-coding RNAs in non-small cell lung cancer as biomarkers and therapeutic targets. PMID:25297942
Evolutionary dynamics of coding and non-coding transcriptomes. PMID:25297727
Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes. PMID:25296969
A four-long non-coding RNA signature in predicting breast cancer survival. PMID:25288503
Promoter analysis reveals globally differential regulation of human long non-coding RNA and protein-coding genes. PMID:25275320
Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes. PMID:25264628
Long non-coding RNAs and control of gene expression in the immune system. PMID:25262537
RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites. PMID:25259926
Could lncRNAs be the missing links in control of mesenchymal stem cell differentiation? PMID:25258250
Epigenetic control of the genome-lessons from genomic imprinting. PMID:25257202
Regulation of transcription by long noncoding RNAs. PMID:25251851
Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients. PMID:25250788
Novel RNA markers in prostate cancer: functional considerations and clinical translation. PMID:25250334
PLEK: a tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme. PMID:25239089
Long non-coding RNAs as a source of new peptides. PMID:25233276
Volatile evolution of long noncoding RNA repertoires: mechanisms and biological implications. PMID:25218058
Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. PMID:25209608
A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer. PMID:25203321
Long non-coding RNAs: emerging players in gastric cancer. PMID:25173641
Purifying selection on splice-related motifs, not expression level nor RNA folding, explains nearly all constraint on human lincRNAs. PMID:25158797
The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites. PMID:25155612
Novel therapeutic targets for pancreatic cancer. PMID:25152585
Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. PMID:25147954
Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq. PMID:25144939
Effects of GWAS-associated genetic variants on lncRNAs within IBD and T1D candidate loci. PMID:25144376
IRBIS: a systematic search for conserved complementarity. PMID:25142064
The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease. PMID:25135968
An evolving view of epigenetic complexity in the brain. PMID:25135967
Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing. PMID:25126716
Complex interactions of transcription factors in mediating cytokine biology in T cells. PMID:25123282
HumanViCe: host ceRNA network in virus infected cells in human. PMID:25120561
Current status of long non-coding RNAs in human cancer with specific focus on colorectal cancer. PMID:25119862
Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer. PMID:25116943
Regulation of the mRNA half-life in breast cancer. PMID:25114848
Long non-coding RNAs in cancer: implications for personalized therapy. PMID:25113790
Long non-coding RNAs in the regulation of the immune response. PMID:25113636
Short stories on zebrafish long noncoding RNAs. PMID:25110965
An emerging role for long non-coding RNAs in cancer metastasis. PMID:25101115
Non-coding RNAs and lipid metabolism. PMID:25093715
Length and GC content variability of introns among teleostean genomes in the light of the metabolic rate hypothesis. PMID:25093416
Phen-Gen: combining phenotype and genotype to analyze rare disorders. PMID:25086502
The persistent contributions of RNA to eukaryotic gen(om)e architecture and cellular function. PMID:25081515
Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans. PMID:25071836
The Missing lnc(RNA) between the pancreatic β-cell and diabetes. PMID:25071830
Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility. PMID:25071823
Expanded identification and characterization of mammalian circular RNAs. PMID:25070500
Single-cell RNA-seq: advances and future challenges. PMID:25053837
Single cell dissection of early kidney development: multilineage priming. PMID:25053437
Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites. PMID:25034687
Decreased expression of a novel lncRNA CADM1-AS1 is associated with poor prognosis in patients with clear cell renal cell carcinomas. PMID:25031695
Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes. PMID:25025429
Physiological roles of long noncoding RNAs: insight from knockout mice. PMID:25022466
Identification and characterization of long intergenic non-coding RNAs related to mouse liver development. PMID:25012394
Transcriptional landscape of repetitive elements in normal and cancer human cells. PMID:25012247
Sex, epilepsy, and epigenetics. PMID:24998474
Computational evidence of NAGNAG alternative splicing in human large intergenic noncoding RNA. PMID:24995327
Research resource: Aorta- and liver-specific ERα-binding patterns and gene regulation by estrogen. PMID:24992180
Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2. PMID:24990076
Noncoding RNAs: key molecules in understanding and treating pain. PMID:24986063
A comprehensive analysis of piRNAs from adult human testis and their relationship with genes and mobile elements. PMID:24981367
Transcriptional regulatory functions of nuclear long noncoding RNAs. PMID:24974018
Panning for Long Noncoding RNAs. PMID:24970166
EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promotes NSCLC cell proliferation and metastasis by affecting the epithelial-mesenchymal transition. PMID:24967960
Non-Coding RNAs as Potential Neuroprotectants against Ischemic Brain Injury. PMID:24961318
Regulation of histone methylation by noncoding RNAs. PMID:24954181
An interactive network of long non-coding RNAs facilitates the Drosophila sex determination decision. PMID:24954180
Expression of transcribed ultraconserved regions of genome in rat cerebral cortex. PMID:24953281
Identification of large intergenic non-coding RNAs in bovine muscle using next-generation transcriptomic sequencing. PMID:24948191
Choice of transcripts and software has a large effect on variant annotation. PMID:24944579
Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. PMID:24939938
Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease. PMID:24936207
Genome-wide identification and characterization of long intergenic non-coding RNAs in Ganoderma lucidum. PMID:24932683
Translation of small open reading frames within unannotated RNA transcripts in Saccharomyces cerevisiae. PMID:24931603
lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA. PMID:24926662
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing. PMID:24920534
Structured RNAs and synteny regions in the pig genome. PMID:24917120
Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes. PMID:24909122
Long noncoding RNAs in cell-fate programming and reprogramming. PMID:24905165
Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression. PMID:24902603
Genome-wide identification of long intergenic noncoding RNA genes and their potential association with domestication in pigs. PMID:24891613
Minireview: transgenerational epigenetic inheritance: focus on endocrine disrupting compounds. PMID:24885575
GAS5 long non-coding RNA in malignant pleural mesothelioma. PMID:24885398
MOIRAI: a compact workflow system for CAGE analysis. PMID:24884663
Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets. PMID:24860013
P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression. PMID:24853421
The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs. PMID:24850885
Conserved expression of lincRNA during human and macaque prefrontal cortex development and maturation. PMID:24847104
Methods for the study of long noncoding RNA in cancer cell signaling. PMID:24839023
Natural antisense transcripts. PMID:24838284
Next-generation sequencing: from understanding biology to personalized medicine. PMID:24832667
Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes. PMID:24831346
An emerging understanding of long noncoding RNAs in kidney cancer. PMID:24816785
Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a. PMID:24810364
The case for junk DNA. PMID:24809441
RAID: a comprehensive resource for human RNA-associated (RNA-RNA/RNA-protein) interaction. PMID:24803509
CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia. PMID:24799664
Recent advances in the involvement of long non-coding RNAs in neural stem cell biology and brain pathophysiology. PMID:24795650
Long non-coding RNA MVIH indicates a poor prognosis for non-small cell lung cancer and promotes cell proliferation and invasion. PMID:24793017
Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs. PMID:24786300
Developmental transcriptome analysis of human erythropoiesis. PMID:24781209
RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE). PMID:24779366
Integrating non-coding RNAs in JAK-STAT regulatory networks. PMID:24778925
The rise of regulatory RNA. PMID:24776770
Identification of non-coding RNAs with a new composite feature in the Hybrid Random Forest Ensemble algorithm. PMID:24771344
Origins and functional evolution of Y chromosomes across mammals. PMID:24759410
Guidelines for investigating causality of sequence variants in human disease. PMID:24759409
A novel tRNA variable number tandem repeat at human chromosome 1q23.3 is implicated as a boundary element based on conservation of a CTCF motif in mouse. PMID:24753417
Next-generation sequencing and epigenomics research: a hammer in search of nails. PMID:24748856
A deep survey of alternative splicing in grape reveals changes in the splicing machinery related to tissue, stress condition and genotype. PMID:24739459
Species-specific alternative splicing leads to unique expression of sno-lncRNAs. PMID:24734784
A novel RNA motif mediates the strict nuclear localization of a long noncoding RNA. PMID:24732794
Elements and machinery of non-coding RNAs: toward their taxonomy. PMID:24731943
TF2LncRNA: identifying common transcription factors for a list of lncRNA genes from ChIP-Seq data. PMID:24729968
Interactive visualization and analysis of large-scale sequencing datasets using ZENBU. PMID:24727769
Functional consequences of splicing of the antisense transcript COOLAIR on FLC transcription. PMID:24725596
Regulation of metabolism by long, non-coding RNAs. PMID:24723937
A short guide to long non-coding RNA gene nomenclature. PMID:24716852
Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation. PMID:24705786
Targeted sequencing for gene discovery and quantification using RNA CaptureSeq. PMID:24705597
ATR checkpoint kinase and CRL1βTRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks. PMID:24700029
RNAs specifically affect gene expression in a length, position and sequence dependent manner. PMID:24696713
Epigenetic regulation of open chromatin in pluripotent stem cells. PMID:24695097
Long noncoding RNAs, emerging players in muscle differentiation and disease. PMID:24685002
The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity. PMID:24681886
Non-coding RNA regulation of synaptic plasticity and memory: implications for aging. PMID:24681292
Regulation of mammary epithelial cell homeostasis by lncRNAs. PMID:24680897
Competing endogenous RNA: the key to posttranscriptional regulation. PMID:24672386
c-Myc-induced, long, noncoding H19 affects cell proliferation and predicts a poor prognosis in patients with gastric cancer. PMID:24671855
Diversity and dynamics of the Drosophila transcriptome. PMID:24670639
DNA conformational transitions induced by supercoiling control transcription in chromatin. PMID:24653646
Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing. PMID:24651478
Molecular mechanisms of long ncRNAs in neurological disorders. PMID:24624135
Long noncoding RNAs during normal and malignant hematopoiesis. PMID:24609766
Long non-coding RNA expression profiles in hereditary haemorrhagic telangiectasia. PMID:24603890
Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs. PMID:24594072
Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA. PMID:24578380
An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription. PMID:24576854
Genome-wide discovery and characterization of maize long non-coding RNAs. PMID:24576388
The de novo sequence origin of two long non-coding genes from an inter-genic region. PMID:24564579
Systematically profiling and annotating long intergenic non-coding RNAs in human embryonic stem cell. PMID:24564552
Long noncoding RNAs in innate and adaptive immunity. PMID:24556411
Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation. PMID:24550934
An evolutionarily conserved long noncoding RNA TUNA controls pluripotency and neural lineage commitment. PMID:24530304
De novo assembly and transcriptome analysis of contrasting sugarcane varieties. PMID:24523899
Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. PMID:24521543
Endogenous RNA interference is driven by copy number. PMID:24520161
Emerging evidence for functional peptides encoded by short open reading frames. PMID:24514441
A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages. PMID:24510058
Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases. PMID:24504737
A network based method for analysis of lncRNA-disease associations and prediction of lncRNAs implicated in diseases. PMID:24498199
The RBPome: where the brains meet the brawn. PMID:24485298
The genomic landscape of Neanderthal ancestry in present-day humans. PMID:24476815
Integrating the roles of long and small non-coding RNA in brain function and disease. PMID:24468823
The evolution of lncRNA repertoires and expression patterns in tetrapods. PMID:24463510
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. PMID:24463464
Interconversion between parallel and antiparallel conformations of a 4H RNA junction in domain 3 of foot-and-mouth disease virus IRES captured by dynamics simulations. PMID:24461020
Evidence for a crucial role of a host non-coding RNA in influenza A virus replication. PMID:24440876
Bidirectional promoters are the major source of gene activation-associated non-coding RNAs in mammals. PMID:24438357
Sequencing depth and coverage: key considerations in genomic analyses. PMID:24434847
Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support. PMID:24429688
Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals. PMID:24429298
Contribution of natural antisense transcription to an endogenous siRNA signature in human cells. PMID:24410956
Dissecting the expression landscape of RNA-binding proteins in human cancers. PMID:24410894
X-marks the spot: X-chromosome identification during dosage compensation. PMID:24406325
Sebnif: an integrated bioinformatics pipeline for the identification of novel large intergenic noncoding RNAs (lincRNAs)--application in human skeletal muscle cells. PMID:24400097
Computational approaches in detecting non- coding RNA. PMID:24396270
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. PMID:24393600
Dynamic expression of long non-coding RNAs (lncRNAs) in adult zebrafish. PMID:24391796
RNA sequencing of the exercise transcriptome in equine athletes. PMID:24391776
Intravenous transplants of human adipose-derived stem cell protect the brain from traumatic brain injury-induced neurodegeneration and motor and cognitive impairments: cell graft biodistribution and soluble factors in young and aged rats. PMID:24381292
Probing the phenomics of noncoding RNA. PMID:24381251
An association-adjusted consensus deleterious scheme to classify homozygous Mis-sense mutations for personal genome interpretation. PMID:24365473
Divergent transcription is associated with promoters of transcriptional regulators. PMID:24365181
CHD1L: a novel oncogene. PMID:24359616
Combining DGE and RNA-sequencing data to identify new polyA+ non-coding transcripts in the human genome. PMID:24357408
Small non-coding RNAs add complexity to the RNA pathogenic mechanisms in trinucleotide repeat expansion diseases. PMID:24348326
Identification of expressed and conserved human noncoding RNAs. PMID:24344320
Emerging epigenetic mechanisms of long non-coding RNAs. PMID:24342564
Clinical and molecular genetics of the phosphodiesterases (PDEs). PMID:24311737
Tackling structures of long noncoding RNAs. PMID:24304541
Long non-coding RNAs: new players in cell differentiation and development. PMID:24296535
Long noncoding RNAs: fresh perspectives into the RNA world. PMID:24290031
Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs. PMID:24289259
NONCODEv4: exploring the world of long non-coding RNA genes. PMID:24285305
Characterization of the human ESC transcriptome by hybrid sequencing. PMID:24282307
Genetic and epigenetic regulation of human lincRNA gene expression. PMID:24268656
Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification. PMID:24265805
Global bidirectional transcription of the Epstein-Barr virus genome during reactivation. PMID:24257595
Transcriptome sequencing during mouse brain development identifies long non-coding RNAs functionally involved in neurogenic commitment. PMID:24240175
Expression analysis and in silico characterization of intronic long noncoding RNAs in renal cell carcinoma: emerging functional associations. PMID:24238219
Functional insights into the role of nuclear-retained long noncoding RNAs in gene expression control in mammalian cells. PMID:24233053
Identification of novel transcripts and noncoding RNAs in bovine skin by deep next generation sequencing. PMID:24225384
ANRIL/CDKN2B-AS shows two-stage clade-specific evolution and becomes conserved after transposon insertions in simians. PMID:24225082
Gene regulation by antisense transcription. PMID:24217315
Regulatory Roles for Long ncRNA and mRNA. PMID:24216986
Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. PMID:24200680
A long non-coding RNA promotes full activation of adult gene expression in the chicken α-globin domain. PMID:24196393
A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development. PMID:24195446
Evolutionary conservation of long non-coding RNAs; sequence, structure, function. PMID:24184936
Functional transcriptomics in the post-ENCODE era. PMID:24172201
The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage. PMID:24168400
Transcriptome interrogation of human myometrium identifies differentially expressed sense-antisense pairs of protein-coding and long non-coding RNA genes in spontaneous labor at term. PMID:24168098
Gene regulation by non-coding RNAs. PMID:24164576
Long noncoding RNAs as metazoan developmental regulators. PMID:24150236
Sense-antisense gene pairs: sequence, transcription, and structure are not conserved between human and mouse. PMID:24133500
Long non-coding RNA expression profiling of mouse testis during postnatal development. PMID:24130740
Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network. PMID:24129253
A single-molecule long-read survey of the human transcriptome. PMID:24108091
Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression. PMID:24098911
The landscape of viral expression and host gene fusion and adaptation in human cancer. PMID:24085110
The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. PMID:24076601
Targeted disruption of Hotair leads to homeotic transformation and gene derepression. PMID:24075995
Computational prediction of associations between long non-coding RNAs and proteins. PMID:24063787
Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs. PMID:24059539
Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes. PMID:24058882
Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation. PMID:24056746
3' terminal diversity of MRP RNA and other human noncoding RNAs revealed by deep sequencing. PMID:24053768
Long non-coding RNA identification over mouse brain development by integrative modeling of chromatin and genomic features. PMID:24038472
The long non-coding RNA Fendrr links epigenetic control mechanisms to gene regulatory networks in mammalian embryogenesis. PMID:24036695
Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division. PMID:24026178
TINCR, staufen1, and cellular differentiation. PMID:24019000
Noncoding RNA in oncogenesis: a new era of identifying key players. PMID:24013378
The complexity of bladder cancer: long noncoding RNAs are on the stage. PMID:24006935
Non-coding RNAs turn up the heat: an emerging layer of novel regulators in the mammalian heat shock response. PMID:24002685
Predicting helical topologies in RNA junctions as tree graphs. PMID:23991010
microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus. PMID:23985560
Low expression of long noncoding RNA GAS6-AS1 predicts a poor prognosis in patients with NSCLC. PMID:23979857
Identification and characterization of long non-coding RNAs related to mouse embryonic brain development from available transcriptomic data. PMID:23967161
Non-coding RNAs and cancer. PMID:23965974
Limited evidence for evolutionarily conserved targeting of long non-coding RNAs by microRNAs. PMID:23962258
Comprehensive characterization of 10,571 mouse large intergenic noncoding RNAs from whole transcriptome sequencing. PMID:23951020
Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts. PMID:23892401
Epigenetic mechanisms and non-coding RNAs in osteoarthritis. PMID:23888362
Detecting and comparing non-coding RNAs in the high-throughput era. PMID:23887659
Long non-coding RNAs in haematological malignancies. PMID:23887658
Computational detection of abundant long-range nucleotide covariation in Drosophila genomes. PMID:23887147
Minireview: Long noncoding RNAs: new "links" between gene expression and cellular outcomes in endocrinology. PMID:23885095
MelanomaDB: A Web Tool for Integrative Analysis of Melanoma Genomic Information to Identify Disease-Associated Molecular Pathways. PMID:23875173
Transcription factor binding profiles reveal cyclic expression of human protein-coding genes and non-coding RNAs. PMID:23874175
Transcriptome analyses of the human retina identify unprecedented transcript diversity and 3.5 Mb of novel transcribed sequence via significant alternative splicing and novel genes. PMID:23865674
Human Transcriptome and Chromatin Modifications: An ENCODE Perspective. PMID:23843771
Long noncoding RNA: a new player of heart failure? PMID:23835777
Chromatin-bound RNA and the neurobiology of psychiatric disease. PMID:23831425
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. PMID:23828888
lincRNAs: genomics, evolution, and mechanisms. PMID:23827673
Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PMID:23818866
Long non-coding RNAs: novel targets for nervous system disease diagnosis and therapy. PMID:23817781
Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. PMID:23810193
The intertwining of transposable elements and non-coding RNAs. PMID:23803660
Separating homeologs by phasing in the tetraploid wheat transcriptome. PMID:23800085
The non-coding road towards cardiac regeneration. PMID:23797382
Getting to the heart of the matter: long non-coding RNAs in cardiac development and disease. PMID:23756463
Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex resembles humans. PMID:23754422
Build a braveheart: the missing linc (RNA). PMID:23743224
UpSETing chromatin during non-coding RNA production. PMID:23738864
Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer. PMID:23728290
Long non-coding RNA: a new player in cancer. PMID:23725405
linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cis. PMID:23723417
Targeting long non-coding RNA to therapeutically upregulate gene expression. PMID:23722346
A brief review on the Human Encyclopedia of DNA Elements (ENCODE) project. PMID:23722115
Gene regulation by the act of long non-coding RNA transcription. PMID:23721193
New gene expression pipelines gush lncRNAs. PMID:23714047
Mutations within lncRNAs are effectively selected against in fruitfly but not in human. PMID:23710818
The Norway spruce genome sequence and conifer genome evolution. PMID:23698360
Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. PMID:23698349
On the classification of long non-coding RNAs. PMID:23696037
HOX antisense lincRNA HOXA-AS2 is an apoptosis repressor in all trans retinoic acid treated NB4 promyelocytic leukemia cells. PMID:23649634
From genetics of inflammatory bowel disease towards mechanistic insights. PMID:23639549
Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs. PMID:23637635
The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing. PMID:23628989
Non-coding RNAs in the development of sensory organs and related diseases. PMID:23588489
Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity. PMID:23586759
Conserved expression of natural antisense transcripts in mammals. PMID:23577827
Exploring the RNA world in hematopoietic cells through the lens of RNA-binding proteins. PMID:23550653
MicroRNA regulation of T-cell differentiation and function. PMID:23550639
Long noncoding RNAs: new players in the molecular mechanism for maintenance and differentiation of pluripotent stem cells. PMID:23528033
Genomic and epigenomic insights into nutrition and brain disorders. PMID:23503168
Long noncoding RNAs: cellular address codes in development and disease. PMID:23498938
Structure and function of long noncoding RNAs in epigenetic regulation. PMID:23463315
Bridging epigenomics and complex disease: the basics. PMID:23463237
Non-Coding RNAs: Functional Aspects and Diagnostic Utility in Oncology. PMID:23455466
Accurate identification and analysis of human mRNA isoforms using deep long read sequencing. PMID:23450794
Transcriptome analyses of primitively eusocial wasps reveal novel insights into the evolution of sociality and the origin of alternative phenotypes. PMID:23442883
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells. PMID:23382218
Epigenetic mechanisms in mood disorders: targeting neuroplasticity. PMID:23376737
Braveheart, a long noncoding RNA required for cardiovascular lineage commitment. PMID:23352431
Regulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and function. PMID:23337534
Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment. PMID:23332363
Molecular mechanisms and function prediction of long noncoding RNA. PMID:23319885
Sizing up long non-coding RNAs: do lncRNAs have secondary and tertiary structure? PMID:23267412
Genetic association suggests that SMOC1 mediates between prenatal sex hormones and digit ratio. PMID:23263445
MicroRNAs in opioid addiction: elucidating evolution. PMID:23233859
CRNDE: A Long Non-Coding RNA Involved in CanceR, Neurobiology, and DEvelopment. PMID:23226159
Stabilization of human interferon-α1 mRNA by its antisense RNA. PMID:23224365
LncRNAs have a say in protein translation. PMID:23208421
The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics. PMID:23203872
Transposable elements reveal a stem cell-specific class of long noncoding RNAs. PMID:23181609
Strategies to identify long noncoding RNAs involved in gene regulation. PMID:23126680
Long noncoding RNAs as sinks in Prader-Willi syndrome. PMID:23102265
Neurodegeneration as an RNA disorder. PMID:23063563
GENCODE: the reference human genome annotation for The ENCODE Project. PMID:22955987
Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome. PMID:22955982
Long noncoding RNAs are rarely translated in two human cell lines. PMID:22955977
Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs. PMID:22955974
Toward mapping the biology of the genome. PMID:22955973
What does our genome encode? PMID:22955972
Decoding the human genome. PMID:22955971
An integrated encyclopedia of DNA elements in the human genome. PMID:22955616
GENCODE: the reference human genome annotation for The ENCODE Project PubMed citations: 2315.

2315 articles citing: GENCODE: the reference human genome annotation for The ENCODE Project

RNA sequencing reveals dynamic expression of spleen lncRNAs and mRNAs in Beagle dogs infected by Toxocara canis. PMID:35927758
Exploring the lncRNA localization landscape within the retinal pigment epithelium under normal and stress conditions. PMID:35883037
Chronology of natural selection in Oceanian genomes. PMID:35880026
Oncogene addiction to GNAS in GNASR201 mutant tumors. PMID:35879396
Functional interplay between long non-coding RNAs and Breast CSCs. PMID:35864503
ISR8/IRF1-AS1 Is Relevant for IFNα and NF-κB Responses. PMID:35860270
Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers. PMID:35843982
Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder. PMID:35840799
Cancer type classification using plasma cell-free RNAs derived from human and microbes. PMID:35816095
Monocytic-Myeloid Derived Suppressor Cells Suppress T-Cell Responses in Recovered SARS CoV2-Infected Individuals. PMID:35812392
Bioinformatics Approaches for Determining the Functional Impact of Repetitive Elements on Non-coding RNAs. PMID:35796972
Construction of a Prognostic Immune-Related LncRNA Risk Model for Gastric Cancer. PMID:35794986
Comprehensive Analysis of LINC01615 in Head and Neck Squamous Cell Carcinoma: A Hub Biomarker Identified by Machine Learning and Experimental Validation. PMID:35794984
Exploring the Potential of Pyroptosis-Related Genes in Predicting Prognosis and Immunological Characteristics of Pancreatic Cancer From the Perspective of Genome and Transcriptome. PMID:35785176
Temporal Whole-Transcriptomic Analysis of Characterized In Vitro and Ex Vivo Primary Nasal Epithelia. PMID:35784475
DESSO-DB: A web database for sequence and shape motif analyses and identification. PMID:35782725
Integrative mRNA and Long Noncoding RNA Analysis Reveals the Regulatory Network of Floral Bud Induction in Longan (Dimocarpus longan Lour.). PMID:35774802
Microbiota, not host origin drives ex vivo intestinal epithelial responses. PMID:35758256
The origin of bladder cancer from mucosal field effects. PMID:35747385
Unexpected Effect of IL-1β on the Function of GABAA Receptors in Pediatric Focal Cortical Dysplasia. PMID:35741692
Non-Coding RNA Networks as Potential Novel Biomarker and Therapeutic Target for Sepsis and Sepsis-Related Multi-Organ Failure. PMID:35741168
The Long Non-Coding RNA GOMAFU in Schizophrenia: Function, Disease Risk, and Beyond. PMID:35741078
Construction and validation of N6-methyladenosine long non-coding RNAs signature of prognostic value for early biochemical recurrence of prostate cancer. PMID:35731271
The intestinal microbiota influences the microenvironment of metastatic colon cancer by targeting miRNAs. PMID:35712898
X chromosome inactivation in the human placenta is patchy and distinct from adult tissues. PMID:35712697
A multifunctional locus controls motor neuron differentiation through short and long noncoding RNAs. PMID:35698802
Somatic point mutations are enriched in non-coding RNAs with possible regulatory function in breast cancer. PMID:35672401
The clinical efficiency of transcriptome-based endometrial receptivity assessment (Tb-ERA) in Chinese patients with recurrent implantation failure (RIF): A study protocol for a prospective randomized controlled trial. PMID:35669489
Tangled quest of post-COVID-19 infection-caused neuropathology and what 3P nano-bio-medicine can solve? PMID:35668839
Evaluating the Immune Response in Treatment-Naive Hospitalised Patients With Influenza and COVID-19. PMID:35663963
The LINC01929/miR-6875-5p/ADAMTS12 Axis in the ceRNA Network Regulates the Development of Advanced Bladder Cancer. PMID:35646642
Deep Splicer: A CNN Model for Splice Site Prediction in Genetic Sequences. PMID:35627292
Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages. PMID:35619054
Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance. PMID:35618311
Identification of Long Noncoding RNAs Involved in Eyelid Pigmentation of Hereford Cattle. PMID:35601493
Berberine and Oligomeric Proanthocyanidins Exhibit Synergistic Efficacy Through Regulation of PI3K-Akt Signaling Pathway in Colorectal Cancer. PMID:35600365
Immune Subtype Profiling and Establishment of Prognostic Immune-Related lncRNA Pairs in Human Ovarian Cancer. PMID:35578596
Progresses in epigenetic studies of asthma from the perspective of high-throughput analysis technologies: a narrative review. PMID:35571411
The Role of Non-Coding RNAs in the Human Placenta. PMID:35563893
The Role of Epigenetics in Primary Biliary Cholangitis. PMID:35563266
Skin-Expressing lncRNAs in Inflammatory Responses. PMID:35559048
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. PMID:35551307
Identification of Prognostic Biomarkers for Glioblastoma Based on Transcriptome and Proteome Association Analysis. PMID:35538679
A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. PMID:35538076
Spatial epitranscriptomics reveals A-to-I editome specific to cancer stem cell microniches. PMID:35534484
Dynamic and widespread control of poly(A) tail length during macrophage activation. PMID:35512831
Native RNA or cDNA Sequencing for Transcriptomic Analysis: A Case Study on Saccharomyces cerevisiae. PMID:35497361
Classification of non-coding variants with high pathogenic impact. PMID:35486646
Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo. PMID:35484247
MafB, WDR77, and ß-catenin interact with each other and have similar genome association profiles. PMID:35482762
Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19. PMID:35479098
SETDB1 fuels the lung cancer phenotype by modulating epigenome, 3D genome organization and chromatin mechanical properties. PMID:35474385
Intraspecific de novo gene birth revealed by presence-absence variant genes in Caenorhabditis elegans. PMID:35464238
Specification of CNS macrophage subsets occurs postnatally in defined niches. PMID:35444273
Tandem Exon Duplications Expanding the Alternative Splicing Repertoire. PMID:35441045
circFAM120B functions as a tumor suppressor in esophageal squamous cell carcinoma via the miR-661/PPM1L axis and the PKR/p38 MAPK/EMT pathway. PMID:35436983
Construction of the Six-lncRNA Prognosis Signature as a Novel Biomarker in Esophageal Squamous Cell Carcinoma. PMID:35432441
REIA: A database for cancer A-to-I RNA editing with interactive analysis. PMID:35414795
Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation. PMID:35411071
Profiling Blood Serum Extracellular Vesicles in Plaque Psoriasis and Psoriatic Arthritis Patients Reveals Potential Disease Biomarkers. PMID:35409365
DUX4 is a multifunctional factor priming human embryonic genome activation. PMID:35402882
CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue. PMID:35396392
Expansion of Schizophrenia Gene Network Knowledge Using Machine Learning Selected Signals From Dorsolateral Prefrontal Cortex and Amygdala RNA-seq Data. PMID:35386517
Ancestry adjustment improves genome-wide estimates of regional intolerance. PMID:35385101
Identification and evaluation of circulating small extracellular vesicle microRNAs as diagnostic biomarkers for patients with indeterminate pulmonary nodules. PMID:35366907
A single-cell analysis of breast cancer cell lines to study tumour heterogeneity and drug response. PMID:35361816
Paleozoic Protein Fossils Illuminate the Evolution of Vertebrate Genomes and Transposable Elements. PMID:35348724
Genome-wide Analysis Reflects Novel 5-Hydroxymethylcytosines Implicated in Diabetic Nephropathy and the Biomarker Potential. PMID:35342902
Analysis of Ferroptosis-Related LncRNAs Signatures Associated with Tumor Immune Infiltration and Experimental Validation in Clear Cell Renal Cell Carcinoma. PMID:35342303
METRO: Multi-ancestry transcriptome-wide association studies for powerful gene-trait association detection. PMID:35334221
Screening and Identification of Putative Long Non-Coding RNA in Childhood Obesity: Evaluation of Their Transcriptional Levels. PMID:35327332
SWI/SNF Antagonism of PRC2 Mediates Estrogen-Induced Progesterone Receptor Expression. PMID:35326450
Modelling the genetic aetiology of complex disease: human-mouse conservation of noncoding features and disease-associated loci. PMID:35317627
StemSC: a cross-dataset human stemness index for single-cell samples. PMID:35313979
Viral long non-coding RNA regulates virus life-cycle and pathogenicity. PMID:35301646
Integrating the Epigenome and Transcriptome of Hepatocellular Carcinoma to Identify Systematic Enhancer Aberrations and Establish an Aberrant Enhancer-Related Prognostic Signature. PMID:35300417
ArhGEF12 activates Rap1A and not RhoA in human dermal microvascular endothelial cells to reduce tumor necrosis factor-induced leak. PMID:35294066
Electrical modulation of transplanted stem cells improves functional recovery in a rodent model of stroke. PMID:35292643
SCAPE: a mixture model revealing single-cell polyadenylation diversity and cellular dynamics during cell differentiation and reprogramming. PMID:35288753
Predicting exon criticality from protein sequence. PMID:35286381
Derivation, Comprehensive Analysis, and Assay Validation of a Pyroptosis-Related lncRNA Prognostic Signature in Patients With Ovarian Cancer. PMID:35280739
C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin. PMID:35273606
Linc-RAM promotes muscle cell differentiation via regulating glycogen phosphorylase activity. PMID:35254536
Methylation- and homologous recombination deficiency-related mutant genes predict the prognosis of lung adenocarcinoma. PMID:35238419
TADA-a machine learning tool for functional annotation-based prioritisation of pathogenic CNVs. PMID:35232478
Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1-mediated tumor eradication. PMID:35230974
Computational Resources for the Interpretation of Variations in Cancer. PMID:35230689
LncRNA Biomarkers of Inflammation and Cancer. PMID:35220568
The Complexity of the Mammalian Transcriptome. PMID:35220563
A multi-dimensional integrative scoring framework for predicting functional variants in the human genome. PMID:35216679
Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type-dependent effects of disease-risk variants. PMID:35213211
Novel Genetic Prognostic Signature for Lung Adenocarcinoma Identified by Differences in Gene Expression Profiles of Low- and High-Grade Histological Subtypes. PMID:35204661
Functional Interactions Between lncRNAs/circRNAs and miRNAs: Insights Into Rheumatoid Arthritis. PMID:35197980
Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer. PMID:35191482
A comparison of experimental assays and analytical methods for genome-wide identification of active enhancers. PMID:35177836
Robust Transcriptional Profiling and Identification of Differentially Expressed Genes With Low Input RNA Sequencing of Adult Hippocampal Neural Stem and Progenitor Populations. PMID:35173579
Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression. PMID:35158906
Serum RNAs can predict lung cancer up to 10 years prior to diagnosis. PMID:35147498
Secreted Toxins From Staphylococcus aureus Strains Isolated From Keratinocyte Skin Cancers Mediate Pro-tumorigenic Inflammatory Responses in the Skin. PMID:35145494
The Carbon Footprint of Bioinformatics. PMID:35143670
Bioinformatic Analyses of the Ferroptosis-Related lncRNAs Signature for Ovarian Cancer. PMID:35127813
Multi-omic profiling of peritoneal metastases in gastric cancer identifies molecular subtypes and therapeutic vulnerabilities. PMID:35121863
A seven-lncRNA signature for predicting prognosis in breast carcinoma. PMID:35116701
CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression. PMID:35108062
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study. PMID:35106505
Haplotype-based inference of the distribution of fitness effects. PMID:35100400
GenomeTornadoPlot: A novel R package for CNV visualization and focality analysis. PMID:35099519
Long Non-coding RNA ZFPM2-AS1: A Novel Biomarker in the Pathogenesis of Human Cancers. PMID:35098483
CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma. PMID:35070495
Integrated clinical characteristics and omics analysis identifies a ferroptosis and iron-metabolism-related lncRNA signature for predicting prognosis and therapeutic responses in ovarian cancer. PMID:35057848
Transcriptional Analysis-Based Alterations Affecting Neuritogenesis of the Peripheral Nervous System in Psoriasis. PMID:35054504
Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains. PMID:35033173
Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period. PMID:35030990
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia. PMID:35013142
Titanium with nanotopography attenuates the osteoclast-induced disruption of osteoblast differentiation by regulating histone methylation. PMID:35012895
Genomic studies controvert the existence of the CUX1 p75 isoform. PMID:34997000
Limb development genes underlie variation in human fingerprint patterns. PMID:34995520
Universal annotation of the human genome through integration of over a thousand epigenomic datasets. PMID:34991667
JAFFAL: detecting fusion genes with long-read transcriptome sequencing. PMID:34991664
The importance of enhancer methylation for epigenetic regulation of tumorigenesis in squamous lung cancer. PMID:34987166
Deconvolving Clinically Relevant Cellular Immune Cross-talk from Bulk Gene Expression Using CODEFACS and LIRICS Stratifies Patients with Melanoma to Anti-PD-1 Therapy. PMID:34983745
Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer. PMID:34980144
LncRNA PCAT19 induced by SP1 and acted as oncogene in gastric cancer competitively binding to miR429 and upregulating DHX9. PMID:34976174
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis. PMID:34957112
Network Integration Analysis and Immune Infiltration Analysis Reveal Potential Biomarkers for Primary Open-Angle Glaucoma. PMID:34926471
Evolving features of human cortical development and the emerging roles of non-coding RNAs in neural progenitor cell diversity and function. PMID:34921638
Alternative polyadenylation is a determinant of oncogenic Ras function. PMID:34919436
Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation. PMID:34910919
β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development. PMID:34910547
Emerging Roles of Long Noncoding RNAs in Immuno-Oncology. PMID:34900986
Long non-coding RNAs as possible therapeutic targets in protozoa, and in Schistosoma and other helminths. PMID:34859292
Integrative Analysis of Epigenome and Transcriptome Data Reveals Aberrantly Methylated Promoters and Enhancers in Hepatocellular Carcinoma. PMID:34858848
Key Markers Involved in the Anticolon Cancer Response of CD8+ T Cells through the Regulation of Cholesterol Metabolism. PMID:34858500
An autoimmune stem-like CD8 T cell population drives type 1 diabetes. PMID:34847567
Analysis of the long noncoding RNA profiles of RD and SH-SY5Y cells infected with coxsackievirus B5, using RNA sequencing. PMID:34839420
Predictive modeling of gene expression regulation. PMID:34837938
Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. PMID:34836952
ATR inhibition enables complete tumour regression in ALK-driven NB mouse models. PMID:34819497
A novel role for vaping in mitochondrial gene dysregulation and inflammation fundamental to disease development. PMID:34815430
Genome-wide identification and characterization of circular RNA m6A modification in pancreatic cancer. PMID:34798904
Potential biomarkers of abnormal osseointegration of implants in type II diabetes mellitus. PMID:34794414
PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia. PMID:34788382
Muscle fibrosis and maladaptation occur progressively in CKD and are rescued by dialysis. PMID:34784301
Differential Expression Profiles of lncRNA Following LPS-Induced Inflammation in Bovine Mammary Epithelial Cells. PMID:34778437
Novel and Annotated Long Noncoding RNAs Associated with Ischemia in the Human Heart. PMID:34768754
ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma. PMID:34763718
The Role of Long Non-coding RNAs in Human Imprinting Disorders: Prospective Therapeutic Targets. PMID:34760887
Klf5 establishes bi-potential cell fate by dual regulation of ICM and TE specification genes. PMID:34758315
FusionGDB 2.0: fusion gene annotation updates aided by deep learning. PMID:34755868
An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. PMID:34746695
Comprehensive analysis of N6 -methyladenosine-related long non-coding RNAs for prognosis prediction in liver hepatocellular carcinoma. PMID:34741346
Haplotype-aware variant calling with PEPPER-Margin-DeepVariant enables high accuracy in nanopore long-reads. PMID:34725481
Derivation and Comprehensive Analysis of Aging Patterns in Patients with Bladder Cancer. PMID:34721733
Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection. PMID:34716845
Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse. PMID:34716314
NanoMethViz: An R/Bioconductor package for visualizing long-read methylation data. PMID:34695109
Machine learning applications for therapeutic tasks with genomics data. PMID:34693370
Muscle Regeneration and RNA: New Perspectives for Ancient Molecules. PMID:34685492
Anthocyanins from Aristotelia chilensis Prevent Olanzapine-Induced Hepatic-Lipid Accumulation but Not Insulin Resistance in Skeletal Muscle Cells. PMID:34684731
IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies. PMID:34675383
Quantifying full-length circular RNAs in cancer. PMID:34663689
Comprehensive Genomic Characterization Analysis Identifies an Oncogenic Pseudogene RP11-3543B.1 in Human Gastric Cancer. PMID:34660601
The key role of NLRP3 and STING in APOL1-associated podocytopathy. PMID:34651582
Building the mega single-cell transcriptome ocular meta-atlas. PMID:34651173
Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation. PMID:34649612
Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes. PMID:34642339
Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin. PMID:34635836
Diverse functional elements in RNA predicted transcriptome-wide by orthogonal RNA structure probing. PMID:34634799
Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes. PMID:34621263
Multi-tiered analyses of honey bees that resist or succumb to parasitic mites and viruses. PMID:34610790
Targeting mutant p53 for cancer therapy: direct and indirect strategies. PMID:34583722
High frequency of intron retention and clustered H3K4me3-marked nucleosomes in short first introns of human long non-coding RNAs. PMID:34579770
Full-length transcriptome analysis and identification of transcript structures in Eimeria necatrix from different developmental stages by single-molecule real-time sequencing. PMID:34579769
Gene Expression Analysis in Patients with Cocaine-Induced Midline Destructive Lesions. PMID:34577784
Performance Evaluation of SpliceAI for the Prediction of Splicing of NF1 Variants. PMID:34573290
TP53 loss initiates chromosomal instability in fallopian tube epithelial cells. PMID:34569598
Comprehensive analyses of glycolysis-related lncRNAs for ovarian cancer patients. PMID:34560889
HIV reprograms host m6Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1. PMID:34545078
Characterization of the Potential Role of NTPCR in Epithelial Ovarian Cancer by Integrating Transcriptomic and Metabolomic Analysis. PMID:34539736
ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer. PMID:34529669
Integrative Epigenome Map of the Normal Human Prostate Provides Insights Into Prostate Cancer Predisposition. PMID:34513844
Predicting Target Genes of San-Huang-Chai-Zhu Formula in Treating ANIT-Induced Acute Intrahepatic Cholestasis Rat Model via Bioinformatics Analysis Combined with Experimental Validation. PMID:34512777
Epigenetic Regulation of the Vascular Endothelium by Angiogenic LncRNAs. PMID:34512715
Integrative analysis of epigenetics data identifies gene-specific regulatory elements. PMID:34508352
A Novel Regulatory Player in the Innate Immune System: Long Non-Coding RNAs. PMID:34502451
Identifying the Main Functional Pathways Associated with Cognitive Resilience to Alzheimer's Disease. PMID:34502030
A compendium of uniformly processed human gene expression and splicing quantitative trait loci. PMID:34493866
A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression. PMID:34493285
The regulatory pattern of target gene expression by aberrant enhancer methylation in glioblastoma. PMID:34482818
Molecular genetic evaluation of pediatric renovascular hypertension due to renal artery stenosis and abdominal aortic coarctation in neurofibromatosis type 1. PMID:34476477
UV-induced reduction in Polycomb repression promotes epidermal pigmentation. PMID:34473941
Precision medicine in diabetes: A non-invasive prenatal diagnostic test for the determination of fetal glucokinase mutations. PMID:34469064
Cap analysis of gene expression (CAGE) and noncoding regulatory elements. PMID:34468849
YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation. PMID:34463254
An approach to gene-based testing accounting for dependence of tests among nearby genes. PMID:34459489
RP11-616M22.7 recapitulates imatinib resistance in gastrointestinal stromal tumor. PMID:34458010
Genome-wide profiling of alternative splicing in glioblastoma and their clinical value. PMID:34445990
High Concentration of an ISS-N1-Targeting Antisense Oligonucleotide Causes Massive Perturbation of the Transcriptome. PMID:34445083
Biomolecule and Bioentity Interaction Databases in Systems Biology: A Comprehensive Review. PMID:34439912
Absent from DNA and protein: genomic characterization of nullomers and nullpeptides across functional categories and evolution. PMID:34433494
Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain. PMID:34425903
The impact of LncRNA dysregulation on clinicopathology and survival of pancreatic cancer: a systematic review and meta-analysis (PRISMA compliant). PMID:34425840
The endogenous mex-3 3´UTR is required for germline repression and contributes to optimal fecundity in C. elegans. PMID:34424904
Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression. PMID:34423893
Long Non-coding RNA RP11-395G23.3 Acts as a Competing Endogenous RNA of miR-124-3p to Regulate ROR1 in Anaplastic Thyroid Carcinoma. PMID:34421987
A novel immune signature to predict the prognosis of patients with hepatocellular carcinoma. PMID:34414957
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19. PMID:34413140
Mechanism-Centric Approaches for Biomarker Detection and Precision Therapeutics in Cancer. PMID:34408770
Long Noncoding RNAs as Emerging Regulators of COVID-19. PMID:34408749
Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast. PMID:34408137
Intussusceptive Angiogenesis in Human Metastatic Malignant Melanoma. PMID:34400131
LncRNA OGFRP1 acts as an oncogene in NSCLC via miR-4640-5p/eIF5A axis. PMID:34389018
Precision treatment exploration of breast cancer based on heterogeneity analysis of lncRNAs at the single-cell level. PMID:34388989
Transcriptomic and Epigenetic Profiling of Fibroblasts in Idiopathic Pulmonary Fibrosis. PMID:34370624
Four Prognosis-Associated lncRNAs Serve as Biomarkers in Ovarian Cancer. PMID:34367239
A Tissue-Specific Landscape of Alternative Polyadenylation, lncRNAs, TFs, and Gene Co-expression Networks in Liriodendron chinense. PMID:34367224
SDE2 is an essential gene required for ribosome biogenesis and the regulation of alternative splicing. PMID:34365507
Cloud Computing Based Immunopeptidomics Utilizing Community Curated Variant Libraries Simplifies and Improves Neo-Antigen Discovery in Metastatic Melanoma. PMID:34359654
Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profiles in Testes of Calves and Sexually Mature Wandong Bulls (Bos taurus). PMID:34359134
Hippocampal Transcriptome Changes After Subarachnoid Hemorrhage in Mice. PMID:34354664
Comprehensive analysis of lncRNAs involved in skeletal muscle development in ZBED6-knockout Bama pigs. PMID:34348644
Pre-pregnancy BMI-associated miRNA and mRNA expression signatures in the placenta highlight a sexually-dimorphic response to maternal underweight status. PMID:34344912
Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland. PMID:34344445
Transgenic mice for in vivo epigenome editing with CRISPR-based systems. PMID:34341582
Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes. PMID:34330920
Systematic Profiling of mRNA Splicing Reveals the Prognostic Predictor and Potential Therapeutic Target for Glioblastoma Multiforme. PMID:34326872
The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets. PMID:34326338
lncRNA-PACER upregulates COX-2 and PGE2 through the NF-κB pathway to promote the proliferation and invasion of colorectal-cancer cells. PMID:34316376
Tissue-specific expression of p73 and p63 isoforms in human tissues. PMID:34315849
Web tools to perform long non-coding RNAs analysis in oncology research. PMID:34296748
Gucy2d selectively marks inhibitory dynorphin neurons in the spinal dorsal horn but is dispensable for pain and itch sensitivity. PMID:34296052
Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy. PMID:34292399
Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity. PMID:34284134
Functional annotation of noncoding mutations in cancer. PMID:34282050
Splicing in the Diagnosis of Rare Disease: Advances and Challenges. PMID:34276790
Long Non-coding RNAs: Mechanisms, Experimental, and Computational Approaches in Identification, Characterization, and Their Biomarker Potential in Cancer. PMID:34276764
The circulatory small non-coding RNA landscape in community-acquired pneumonia on intensive care unit admission. PMID:34272809
Epithelial Splicing Regulatory Protein 1 Is Overexpressed in Breast Cancer and Predicts Poor Prognosis for Breast Cancer Patients. PMID:34262011
Comparing the Predictivity of Human Placental Gene, microRNA, and CpG Methylation Signatures in Relation to Perinatal Outcomes. PMID:34255065
DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy. PMID:34238917
Identification and validation of lncRNAs involved in m6A regulation for patients with ovarian cancer. PMID:34238292
A DNA methylation profile of long non-coding RNAs can predict OS in prostate cancer. PMID:34238128
Software Options for the Analysis of MS-Proteomic Data. PMID:34236654
EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer. PMID:34230470
ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions. PMID:34214142
EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance. PMID:34206026
Predicting the Risk Genes of Autism Spectrum Disorders. PMID:34194469
Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation. PMID:34187555
Single-cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions. PMID:34173975
Construction of lncRNA-Mediated ceRNA Network for Investigating Immune Pathogenesis of Ischemic Stroke. PMID:34173933
Dealing with Pseudogenes in Molecular Diagnostics in the Next Generation Sequencing Era. PMID:34165726
Pseudogene Profiling for Cancer Subtype Classification. PMID:34165723
GENCODE Pseudogenes. PMID:34165709
rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo. PMID:34165568
KCNQ1OT1 lncRNA affects the proliferation, apoptosis, and chemoresistance of small cell lung cancer cells via the JAK2/STAT3 axis. PMID:34164525
Experimental Validation of the Noncoding Potential for lncRNAs. PMID:34160810
Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening. PMID:34133938
Potential prognostic markers and significant lncRNA-mRNA co-expression pairs in laryngeal squamous cell carcinoma. PMID:34131588
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. PMID:34127860
Comprehensive analysis of suppressor of cytokine signaling proteins in human breast Cancer. PMID:34120621
H2A.Z acetylation by lincZNF337-AS1 via KAT5 implicated in the transcriptional misregulation in cancer signaling pathway in hepatocellular carcinoma. PMID:34120148
CD27hiCD38hi plasmablasts are activated B cells of mixed origin with distinct function. PMID:34113823
Time trajectories in the transcriptomic response to exercise - a meta-analysis. PMID:34108459
Identification of DNA methylation biomarkers for risk of liver metastasis in early-stage colorectal cancer. PMID:34108011
A microRNA expression and regulatory element activity atlas of the mouse immune system. PMID:34099919
RNA structure probing reveals the structural basis of Dicer binding and cleavage. PMID:34099665
Multiple Omics Integration Reveals Key Circular RNAs in Hepatocellular Carcinoma. PMID:34094907
Bone marrow mesenchymal stem cells and their derived exosomes resolve doxorubicin-induced chemobrain: critical role of their miRNA cargo. PMID:34090498
Identification of 3'-UTR single nucleotide variants and prediction of select protein imbalance in mesial temporal lobe epilepsy patients. PMID:34086756
A panel of 8-lncRNA predicts prognosis of breast cancer patients and migration of breast cancer cells. PMID:34086679
An Informatics Pipeline for Profiling and Annotating RNA Modifications. PMID:34085236
Oncogenic Landscape of Somatic Mutations Perturbing Pan-Cancer lncRNA-ceRNA Regulation. PMID:34079798
The landscape and biological relevance of aberrant alternative splicing events in esophageal squamous cell carcinoma. PMID:34079089
Decoding LncRNAs. PMID:34072257
The Detection and Bioinformatic Analysis of Alternative 3' UTR Isoforms as Potential Cancer Biomarkers. PMID:34070203
HERV-K(HML7) Integrations in the Human Genome: Comprehensive Characterization and Comparative Analysis in Non-Human Primates. PMID:34069102
Human Endogenous Retroviruses (HERVs) and Mammalian Apparent LTRs Retrotransposons (MaLRs) Are Dynamically Modulated in Different Stages of Immunity. PMID:34062989
Long Non-coding RNA RUNDC3A-AS1 Promotes Lung Metastasis of Thyroid Cancer via Targeting the miR-182-5p/ADAM9. PMID:34046406
Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation. PMID:34044218
Lantern: an integrative repository of functional annotations for lncRNAs in the human genome. PMID:34039271
BRIO: a web server for RNA sequence and structure motif scan. PMID:34038531
Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis. PMID:34037083
Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer. PMID:34036938
Selection of Optimal Bioinformatic Tools and Proper Reference for Reducing the Alignment Error in Targeted Sequencing Data. PMID:34026589
Interpretation of deep learning in genomics and epigenomics. PMID:34020542
Identity and compatibility of reference genome resources. PMID:34017945
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics. PMID:34012112
Targeted RNA-seq improves efficiency, resolution, and accuracy of allele specific expression for human term placentas. PMID:34009305
Generation of an isoform-level transcriptome atlas of macrophage activation. PMID:34000296
Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes. PMID:33983929
Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection. PMID:33979654
Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2. PMID:33961735
Kidney Diseases: The Age of Molecular Markers. PMID:33959903
A Human Endogenous Bornavirus-Like Nucleoprotein Encodes a Mitochondrial Protein Associated with Cell Viability. PMID:33952640
Intergenic RNA mainly derives from nascent transcripts of known genes. PMID:33952325
Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3. PMID:33951478
Tumor necrosis factor-induced ArhGEF10 selectively activates RhoB contributing to human microvascular endothelial cell tight junction disruption. PMID:33948992
lncRNA PVT1 in the Pathogenesis and Clinical Management of Renal Cell Carcinoma. PMID:33947142
Detection of new drivers of frequent B-cell lymphoid neoplasms using an integrated analysis of whole genomes. PMID:33945543
Transcriptome prediction performance across machine learning models and diverse ancestries. PMID:33937878
Topography of transcriptionally active chromatin in glioblastoma. PMID:33931443
Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells. PMID:33921066
Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy. PMID:33911285
Identification of candidate PAX2-regulated genes implicated in human kidney development. PMID:33907292
Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits. PMID:33888138
The cis-regulatory effects of modern human-specific variants. PMID:33885362
Genomic Landscapes of Noncoding RNAs Regulating VEGFA and VEGFC Expression in Endothelial Cells. PMID:33875575
Conserved long-range base pairings are associated with pre-mRNA processing of human genes. PMID:33863890
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes. PMID:33859415
Human KIT+ myeloid cells facilitate visceral metastasis by melanoma. PMID:33857287
A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures. PMID:33849996
Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis. PMID:33846360
A large-scale genome-wide gene expression analysis in peripheral blood identifies very few differentially expressed genes related to antidepressant treatment and response in patients with major depressive disorder. PMID:33833401
The structure, function and evolution of a complete human chromosome 8. PMID:33828295
An extended catalogue of tandem alternative splice sites in human tissue transcriptomes. PMID:33826604
Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage. PMID:33824317
Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/β-catenin pathway and associates with favorable prognosis of ovarian cancer. PMID:33820921
Machine Learning Reduced Gene/Non-Coding RNA Features That Classify Schizophrenia Patients Accurately and Highlight Insightful Gene Clusters. PMID:33805976
CALINCA-A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease. PMID:33804736
Differential Methylation in the GSTT1 Regulatory Region in Sudden Unexplained Death and Sudden Unexpected Death in Epilepsy. PMID:33801838
HIV-1 integration sites in CD4+ T cells during primary, chronic, and late presentation of HIV-1 infection. PMID:33784259
Evidence for additive and synergistic action of mammalian enhancers during cell fate determination. PMID:33770473
A transcription-centric model of SNP-age interaction. PMID:33770080
Neuronal enhancers are hotspots for DNA single-strand break repair. PMID:33767446
Aripiprazole as a Candidate Treatment of COVID-19 Identified Through Genomic Analysis. PMID:33762960
Fine-mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians. PMID:33747362
COX2 regulates senescence secretome composition and senescence surveillance through PGE2. PMID:33730589
Mutant non-coding RNA resource in mouse embryonic stem cells. PMID:33729986
Coronary artery disease: differential expression of ceRNAs and interaction analyses. PMID:33708856
Most non-canonical proteins uniquely populate the proteome or immunopeptidome. PMID:33691108
Day-night and seasonal variation of human gene expression across tissues. PMID:33688644
An intriguing characteristic of enhancer-promoter interactions. PMID:33685407
Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas. PMID:33681213
Non-Coding RNAs in Retinoic Acid as Differentiation and Disease Drivers. PMID:33671241
RNA-Seq Implies Divergent Regulation Patterns of LincRNA on Spermatogenesis and Testis Growth in Goats. PMID:33653002
Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia. PMID:33649198
A potential association of RNF219-AS1 with ADHD: Evidence from categorical analysis of clinical phenotypes and from quantitative exploration of executive function and white matter microstructure endophenotypes. PMID:33644999
Genome-Wide Identification and Characterization of Potato Long Non-coding RNAs Associated With Phytophthora infestans Resistance. PMID:33643350
Potential Molecular Mechanism of TNF Superfamily-Related Genes in Glioblastoma Multiforme Based on Transcriptome and Epigenome. PMID:33643183
Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease. PMID:33637690
Identification and Characterisation of Putative Enhancer Elements in Mouse Embryonic Stem Cells. PMID:33623376
Annotation of chromatin states in 66 complete mouse epigenomes during development. PMID:33619351
Uniform genomic data analysis in the NCI Genomic Data Commons. PMID:33619257
Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits. PMID:33607115
Polycomb complexes redundantly maintain epidermal stem cell identity during development. PMID:33602871
Genetic Effects on Transcriptome Profiles in Colon Epithelium Provide Functional Insights for Genetic Risk Loci. PMID:33601062
CD4+ T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities. PMID:33597588
Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects. PMID:33593402
CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens. PMID:33592498
Identification of Functional lncRNAs Associated With Ovarian Endometriosis Based on a ceRNA Network. PMID:33584822
Novel insights into the interaction between long non-coding RNAs and microRNAs in glioma. PMID:33582947
PRMT5 inhibition disrupts splicing and stemness in glioblastoma. PMID:33579912
Benchmark study comparing liftover tools for genome conversion of epigenome sequencing data. PMID:33575605
Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma. PMID:33574286
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment. PMID:33574182
Eight-lncRNA signature of cervical cancer were identified by integrating DNA methylation, copy number variation and transcriptome data. PMID:33557879
Role of Transposable Elements in Gene Regulation in the Human Genome. PMID:33557056
Inhibitory effect of sodium butyrate on colorectal cancer cells and construction of the related molecular network. PMID:33549042
Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. PMID:33545081
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer. PMID:33531470
Consequences of aneuploidy in human fibroblasts with trisomy 21. PMID:33526671
Competing endogenous RNA network analysis explores the key lncRNAs, miRNAs, and mRNAs in type 1 diabetes. PMID:33526014
MicroRNA Profiles in Monocyte-Derived Macrophages Generated by Interleukin-27 and Human Serum: Identification of a Novel HIV-Inhibiting and Autophagy-Inducing MicroRNA. PMID:33525571
Integrating quantitative proteomics with accurate genome profiling of transcription factors by greenCUT&RUN. PMID:33524153
Gene expression signatures of target tissues in type 1 diabetes, lupus erythematosus, multiple sclerosis, and rheumatoid arthritis. PMID:33523973
Identification of Potential Prognostic Competing Triplets in High-Grade Serous Ovarian Cancer. PMID:33519912
Long Non-Coding RNA FENDRR: Gene Structure, Expression, and Biological Relevance. PMID:33513839
Cell-to-Cell Adhesion and Neurogenesis in Human Cortical Development: A Study Comparing 2D Monolayers with 3D Organoid Cultures. PMID:33513360
Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data. PMID:33509077
Systematic analysis of binding of transcription factors to noncoding variants. PMID:33505025
Detection of aberrant splicing events in RNA-seq data using FRASER. PMID:33483494
Transcriptome network analyses in human coronavirus infections suggest a rational use of immunomodulatory drugs for COVID-19 therapy. PMID:33482326
A novel five-lncRNA signature panel improves high-risk survival prediction in patients with cholangiocarcinoma. PMID:33472169
Compression of quantification uncertainty for scRNA-seq counts. PMID:33471073
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain. PMID:33469025
Long Non-Coding RNAs and Their Potential Roles in the Vector-Host-Pathogen Triad. PMID:33466803
Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk. PMID:33462483
DeepLPI: a multimodal deep learning method for predicting the interactions between lncRNAs and protein isoforms. PMID:33461501
PacBio full-length transcriptome of wild apple (Malus sieversii) provides insights into canker disease dynamic response. PMID:33446096
Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease. PMID:33441415
Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures. PMID:33439897
Longitudinal saliva omics responses to immune perturbation: a case study. PMID:33436912
Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity. PMID:33436550
The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis. PMID:33435206
Multi-trait transcriptome-wide association studies with probabilistic Mendelian randomization. PMID:33434493
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. PMID:33432228
Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity. PMID:33431859
Diabetes induced renal complications by leukocyte activation of nuclear factor κ-B and its regulated genes expression. PMID:33424337
Comprehensive characterisation of intronic mis-splicing mutations in human cancers. PMID:33420369
A cross-platform approach identifies genetic regulators of human metabolism and health. PMID:33414548
ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutation. PMID:33411331
Genome-wide identification and characterization of long non-coding RNAs conferring resistance to Colletotrichum gloeosporioides in walnut (Juglans regia). PMID:33407106
Unbiased RNA-Seq-driven identification and validation of reference genes for quantitative RT-PCR analyses of pooled cancer exosomes. PMID:33407103
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. PMID:33402679
Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer. PMID:33402335
TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons. PMID:33393505
Transcriptomic analysis identifies a tumor subtype mRNA classifier for invasive non-functioning pituitary neuroendocrine tumor diagnostics. PMID:33391466
Identification of Critical Genes and Proteins for Stent Restenosis Induced by Esophageal Benign Hyperplasia in Esophageal Cancer. PMID:33391336
Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates. PMID:33378680
Common cell type nomenclature for the mammalian brain. PMID:33372656
Sex and age influence gonadal steroid hormone receptor distributions relative to estrogen receptor β-containing neurons in the mouse hypothalamic paraventricular nucleus. PMID:33341960
Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy. PMID:33335088
FAN-C: a feature-rich framework for the analysis and visualisation of chromosome conformation capture data. PMID:33334380
AnnoLnc: A One-Stop Portal to Systematically Annotate Novel Human Long Noncoding RNAs. PMID:33326073
Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis. PMID:33320851
Liftoff: accurate mapping of gene annotations. PMID:33320174
Functional interaction between long non-coding RNA and microRNA in rheumatoid arthritis. PMID:33319382
The computational approaches of lncRNA identification based on coding potential: Status quo and challenges. PMID:33304463
Our emerging understanding of the roles of long non-coding RNAs in normal liver function, disease, and malignancy. PMID:33294829
MicroRNA expression data of pluripotent and somatic cells and identification of cell type-specific MicroRNAs in pigs. PMID:33294536
CoolMPS: evaluation of antibody labeling based massively parallel non-coding RNA sequencing. PMID:33290507
Screening of T Cell-Related Long Noncoding RNA-MicroRNA-mRNA Regulatory Networks in Non-Small-Cell Lung Cancer. PMID:33274216
Immune-Related Four-lncRNA Signature for Patients with Cervical Cancer. PMID:33274204
GENCODE 2021. PMID:33270111
Deep whole-genome sequencing of multiple proband tissues and parental blood reveals the complex genetic etiology of congenital diaphragmatic hernias. PMID:33263113
dbNSFP v4: a comprehensive database of transcript-specific functional predictions and annotations for human nonsynonymous and splice-site SNVs. PMID:33261662
Improvement of Disease Resistance in Livestock: Application of Immunogenomics and CRISPR/Cas9 Technology. PMID:33260762
Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction. PMID:33257699
Serum RNA Profiling in the 10-Years Period Prior to Diagnosis of Testicular Germ Cell Tumor. PMID:33251139
ProTECT-Prediction of T-Cell Epitopes for Cancer Therapy. PMID:33244314
NAIL: an evolutionarily conserved lncRNA essential for licensing coordinated activation of p38 and NFκB in colitis. PMID:33239342
Global transcriptomic profiling of microcystin-LR or -RR treated hepatocytes (HepaRG). PMID:33235993
An integrative atlas of chicken long non-coding genes and their annotations across 25 tissues. PMID:33235280
A Detailed Flow Cytometric Analysis of Immune Activity Profiles in Molecular Subtypes of Colorectal Cancer. PMID:33228141
Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment. PMID:33217343
Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in Melanoma. PMID:33207206
Genome-Wide Identification of Long Non-coding RNAs in the Gravid Ectoparasite Varroa destructor. PMID:33193688
Plant miRNAs Reduce Cancer Cell Proliferation by Targeting MALAT1 and NEAT1: A Beneficial Cross-Kingdom Interaction. PMID:33193626
Proteoform Identification by Combining RNA-Seq and Top-Down Mass Spectrometry. PMID:33183009
Integrated analysis of transcriptomic and metabolomic data demonstrates the significant role of pyruvate carboxylase in the progression of ovarian cancer. PMID:33177242
deepBase v3.0: expression atlas and interactive analysis of ncRNAs from thousands of deep-sequencing data. PMID:33175131
Transcriptional analysis of metastatic uveal melanoma survival nominates NRP1 as a therapeutic target. PMID:33170593
SVFX: a machine learning framework to quantify the pathogenicity of structural variants. PMID:33168059
Prediction of enhancer-promoter interactions using the cross-cell type information and domain adversarial neural network. PMID:33160328
Towards a better understanding of the low recall of insertion variants with short-read based variant callers. PMID:33148192
Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms. PMID:33129114
Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility. PMID:33126901
Illuminating the dark side of the human transcriptome with long read transcript sequencing. PMID:33126848
A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells. PMID:33112233
mTOR-dependent translation amplifies microglia priming in aging mice. PMID:33108356
Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms. PMID:33106285
LncRNAs in adaptive immunity: role in physiological and pathological conditions. PMID:33094664
PLA2G6 guards placental trophoblasts against ferroptotic injury. PMID:33087576
Network-Based Coexpression Analysis Identifies Functional and Prognostic Long Noncoding RNAs in Hepatocellular Carcinoma. PMID:33083449
Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ. PMID:33081033
Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults. PMID:33071237
Host gene expression modulated by Zika virus infection of human-293 cells. PMID:33059318
An enhanced genetic model of relapsed IGH-translocated multiple myeloma evolutionary dynamics. PMID:33057009
Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation. PMID:33056990
A systematic evaluation of bioinformatics tools for identification of long noncoding RNAs. PMID:33055239
Identification of male infertility-related long non-coding RNAs and their functions based on a competing endogenous RNA network. PMID:33054493
LncExpDB: an expression database of human long non-coding RNAs. PMID:33045751
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D. PMID:32999275
Effects of germline and somatic events in candidate BRCA-like genes on breast-tumor signatures. PMID:32997669
Long noncoding RNA AANCR modulates innate antiviral responses by blocking miR-210-dependent MITA downregulation in teleost fish, Miichthys miiuy. PMID:32997329
Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia. PMID:32993115
Swan: a library for the analysis and visualization of long-read transcriptomes. PMID:32991665
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism. PMID:32978376
Long non-coding RNA AGAP2-AS1 increases the invasiveness of papillary thyroid cancer. PMID:32960785
PRAM: a novel pooling approach for discovering intergenic transcripts from large-scale RNA sequencing experiments. PMID:32958497
IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction-a retrospective propensity score analysis. PMID:32948843
Network analysis of KLF5 targets showing the potential oncogenic role of SNHG12 in colorectal cancer. PMID:32943987
The Landscape of Micro-Inversions Provide Clues for Population Genetic Analysis of Humans. PMID:32929667
Incomplete annotation has a disproportionate impact on our understanding of Mendelian and complex neurogenetic disorders. PMID:32917675
A Quantitative Proteome Map of the Human Body. PMID:32916130
Scavenger: A pipeline for recovery of unaligned reads utilising similarity with aligned reads. PMID:32913631
A polyclonal allelic expression assay for detecting regulatory effects of transcript variants. PMID:32912286
Identification and Characterization of Copy Number-Associated Driver Genes in Esophageal Squamous Cell Carcinoma. PMID:32908901
A role for microRNAs in the epigenetic control of sexually dimorphic gene expression in the human placenta. PMID:32901510
p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo. PMID:32900967
Radiation induces dynamic changes to the T cell repertoire in renal cell carcinoma patients. PMID:32900949
Three-dimensional facial-image analysis to predict heterogeneity of the human ageing rate and the impact of lifestyle. PMID:32895578
Roles of miRNA and lncRNA in triple-negative breast cancer. PMID:32893525
Genome-wide identification of differentially methylated promoters and enhancers associated with response to anti-PD-1 therapy in non-small cell lung cancer. PMID:32879421
Long non-coding RNA CASC8 polymorphisms are associated with the risk of esophageal cancer in a Chinese population. PMID:32875717
The genomic landscape of Mongolian hepatocellular carcinoma. PMID:32873799
Genome-wide analysis of long non-coding RNAs in adult tissues of the melon fly, Zeugodacus cucurbitae (Coquillett). PMID:32867696
Learning the properties of adaptive regions with functional data analysis. PMID:32853200
Genome-Wide Transcriptional Analysis Reveals Alternative Splicing Event Profiles in Hepatocellular Carcinoma and Their Prognostic Significance. PMID:32849842
Systematic Evaluation of the Diagnostic and Prognostic Significance of Competitive Endogenous RNA Networks in Prostate Cancer. PMID:32849794
Identifying Circular RNA and Predicting Its Regulatory Interactions by Machine Learning. PMID:32849764
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. PMID:32839606
Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo. PMID:32821827
Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. PMID:32810435
Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity. PMID:32807990
Promoter CpG Density Predicts Downstream Gene Loss-of-Function Intolerance. PMID:32800095
Ybx1 fine-tunes PRC2 activities to control embryonic brain development. PMID:32792512
circRNAome Profiling in Oral Carcinoma Unveils a Novel circFLNB that Mediates Tumour Growth-Regulating Transcriptional Response. PMID:32785098
Splicing Anomalies in Myeloproliferative Neoplasms: Paving the Way for New Therapeutic Venues. PMID:32784800
The role of exome sequencing in newborn screening for inborn errors of metabolism. PMID:32778825
The Long Non-coding Road to Atherosclerosis. PMID:32772181
CD163+ cytokine-producing cDC2 stimulate intratumoral type 1 T cell responses in HPV16-induced oropharyngeal cancer. PMID:32771994
Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders. PMID:32764605
Demystifying "drop-outs" in single-cell UMI data. PMID:32762710
Comprehensive Network Analysis Reveals Alternative Splicing-Related lncRNAs in Hepatocellular Carcinoma. PMID:32760422
A limited set of transcriptional programs define major cell types. PMID:32759341
Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres. PMID:32755577
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN. PMID:32754899
MYBPC3 Haplotype Linked to Hypertrophic Cardiomyopathy in Rhesus Macaques (Macaca mulatta). PMID:32753092
Identification of the key genes and characterizations of Tumor Immune Microenvironment in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC). PMID:32742444
Supervised enhancer prediction with epigenetic pattern recognition and targeted validation. PMID:32737473
Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies. PMID:32737316
Methodologies for Transcript Profiling Using Long-Read Technologies. PMID:32733532
Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method. PMID:32732980
Perspectives on ENCODE. PMID:32728248
Spatiotemporal DNA methylome dynamics of the developing mouse fetus. PMID:32728242
An atlas of dynamic chromatin landscapes in mouse fetal development. PMID:32728240
Transcriptional activity and strain-specific history of mouse pseudogenes. PMID:32728065
RADAR: annotation and prioritization of variants in the post-transcriptional regulome of RNA-binding proteins. PMID:32727537
HOTTIP polymorphism may affect gastric cancer susceptibility by altering HOTTIP expression. PMID:32725141
Placental genomic and epigenomic signatures associated with infant birth weight highlight mechanisms involved in collagen and growth factor signaling. PMID:32721520
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. PMID:32716134
Altered Long Noncoding RNA Expression Profile in Multiple Myeloma Patients with Bisphosphonate-Induced Osteonecrosis of the Jaw. PMID:32714991
The Heterogeneous Landscape and Early Evolution of Pathogen-Associated CpG Dinucleotides in SARS-CoV-2. PMID:32714120
The RNA exosome shapes the expression of key protein-coding genes. PMID:32710631
Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas. PMID:32703790
Comprehensive Analysis of Differentially Expressed lncRNAs in Gastric Cancer. PMID:32695786
Genetic architecture of complex traits and disease risk predictors. PMID:32694572
Reference genome and transcriptome informed by the sex chromosome complement of the sample increase ability to detect sex differences in gene expression from RNA-Seq data. PMID:32693839
The long non-coding RNA HLNC1 potentiates hepatocellular carcinoma progression via interaction with USP49. PMID:32691951
Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes. PMID:32686750
Long noncoding RNA MARL regulates antiviral responses through suppression miR-122-dependent MAVS downregulation in lower vertebrates. PMID:32678830
RNA-Seq Transcriptome Analysis Reveals Long Terminal Repeat Retrotransposon Modulation in Human Peripheral Blood Mononuclear Cells after In Vivo Lipopolysaccharide Injection. PMID:32669333
Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. PMID:32668256
Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment. PMID:32668240
Unified inference of missense variant effects and gene constraints in the human genome. PMID:32667917
Total Functional Score of Enhancer Elements Identifies Lineage-Specific Enhancers That Drive Differentiation of Pancreatic Cells. PMID:32655276
Chromosome-level de novo assembly of the pig-tailed macaque genome using linked-read sequencing and HiC proximity scaffolding. PMID:32649757
Macrocyclization of a Ligand Targeting a Toxic RNA Dramatically Improves Potency. PMID:32649032
DrugSniper, a Tool to Exploit Loss-Of-Function Screens, Identifies CREBBP as a Predictive Biomarker of VOLASERTIB in Small Cell Lung Carcinoma (SCLC). PMID:32645997
miR-7 Reduces Breast Cancer Stem Cell Metastasis via Inhibiting RELA to Decrease ESAM Expression. PMID:32637582
Characterization of cell-free breast cancer patient-derived scaffolds using liquid chromatography-mass spectrometry/mass spectrometry data and RNA sequencing data. PMID:32637480
Network of clinically-relevant lncRNAs-mRNAs associated with prognosis of hepatocellular carcinoma patients. PMID:32636408
Impact of Losing hRpn13 Pru or UCHL5 on Proteasome Clearance of Ubiquitinated Proteins and RA190 Cytotoxicity. PMID:32631902
Bioinformatic analysis of the potential molecular mechanism of PAK7 expression in glioblastoma. PMID:32626960
Germline de novo mutation rates on exons versus introns in humans. PMID:32620809
Insights into lncRNAs in Alzheimer's disease mechanisms. PMID:32605500
Quantification of translation uncovers the functions of the alternative transcriptome. PMID:32601440
Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids. PMID:32594135
Long non-coding RNA profiling of pediatric Medulloblastoma. PMID:32591022
Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor. PMID:32571799
The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways. PMID:32561656
Intellectual disability-associated gene ftsj1 is responsible for 2'-O-methylation of specific tRNAs. PMID:32558197
Inferring changes in histone modification during cell differentiation by ancestral state estimation based on phylogenetic trees of cell types: Human hematopoiesis as a model case. PMID:32550550
Long Noncoding RNAs in Diffuse Large B-Cell Lymphoma: Current Advances and Perspectives. PMID:32547063
Weighted Gene Coexpression Network Analysis Reveals the Dynamic Transcriptome Regulation and Prognostic Biomarkers of Hepatocellular Carcinoma. PMID:32523331
Properties of structural variants and short tandem repeats associated with gene expression and complex traits. PMID:32522982
WHSC1 monomethylates histone H1 and induces stem-cell like features in squamous cell carcinoma of the head and neck. PMID:32497898
Genomic analyses of early responses to radiation inglioblastoma reveal new alterations at transcription,splicing, and translation levels. PMID:32488114
The lncRNA RUNX1-IT1 regulates C-FOS transcription by interacting with RUNX1 in the process of pancreatic cancer proliferation, migration and invasion. PMID:32487998
The Impact of Recessive Deleterious Variation on Signals of Adaptive Introgression in Human Populations. PMID:32487519
Hypermethylation of the miR-155 gene in the whole blood and decreased plasma level of miR-155 in rheumatoid arthritis. PMID:32484820
Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism. PMID:32483258
Dynamic TF-lncRNA Regulatory Networks Revealed Prognostic Signatures in the Development of Ovarian Cancer. PMID:32478062
Frequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myeloma. PMID:32477831
Discovery of a transcriptomic core of genes shared in 8 primary retinoblastoma with a novel detection score analysis. PMID:32474753
Age-dependent effect of APOE and polygenic component on Alzheimer's disease. PMID:32464432
HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p. PMID:32457911
Geminin is required for Hox gene regulation to pattern the developing limb. PMID:32450229
SNHG7 is a lncRNA oncogene controlled by Insulin-like Growth Factor signaling through a negative feedback loop to tightly regulate proliferation. PMID:32444795
miRactDB characterizes miRNA-gene relation switch between normal and cancer tissues across pan-cancer. PMID:32436932
Progress, Challenges, and Surprises in Annotating the Human Genome. PMID:32421357
Codon usage similarity between viral and some host genes suggests a codon-specific translational regulation. PMID:32395662
ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms. PMID:32393825
Transcriptome analysis of neural progenitor cells derived from Lowe syndrome induced pluripotent stem cells: identification of candidate genes for the neurodevelopmental and eye manifestations. PMID:32393163
Identification of Key Players Involved in CoCl2 Hypoxia Induced Pulmonary Artery Hypertension in vitro. PMID:32391042
All-Trans Retinoic Acid Stimulates Viral Mimicry, Interferon Responses and Antigen Presentation in Breast-Cancer Cells. PMID:32384653
A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. PMID:32381040
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. PMID:32359397
Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression. PMID:32358485
Blood-based biomarkers for early detection of esophageal squamous cell carcinoma. PMID:32351288
CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes. PMID:32345360
Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci. PMID:32340287
The Construction and Analysis of the Aberrant lncRNA-miRNA-mRNA Network in Adipose Tissue from Type 2 Diabetes Individuals with Obesity. PMID:32337289
Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators. PMID:32330446
Predicting target genes of non-coding regulatory variants with IRT. PMID:32330225
O-GlcNAc regulates gene expression by controlling detained intron splicing. PMID:32329777
Transcriptome Analyses of lncRNAs in A2E-Stressed Retinal Epithelial Cells Unveil Advanced Links between Metabolic Impairments Related to Oxidative Stress and Retinitis Pigmentosa. PMID:32326576
STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer. PMID:32323921
Detection of Allosteric Effects of lncRNA Secondary Structures Altered by SNPs in Human Diseases. PMID:32322582
Genome‑wide DNA methylation regulation analysis of long non‑coding RNAs in glioblastoma. PMID:32319552
Effect for Human Genomic Variation During the BMP4-Induced Conversion From Pluripotent Stem Cells to Trophoblast. PMID:32318089
Complete characterization of the human immune cell transcriptome using accurate full-length cDNA sequencing. PMID:32312742
Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies. PMID:32310941
DolphinNext: a distributed data processing platform for high throughput genomics. PMID:32306927
Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. PMID:32302523
Ex Vivo Organoid Cultures Reveal the Importance of the Tumor Microenvironment for Maintenance of Colorectal Cancer Stem Cells. PMID:32290033
Misuse of RPKM or TPM normalization when comparing across samples and sequencing protocols. PMID:32284352
Comparability of the small RNA secretome across human biofluids concomitantly collected from healthy adults. PMID:32275679
Modulator-Dependent RBPs Changes Alternative Splicing Outcomes in Kidney Cancer. PMID:32273884
Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex. PMID:32268104
Differences in gene-expression profiles in breast cancer between African and European-ancestry women. PMID:32267939
The UCSC repeat browser allows discovery and visualization of evolutionary conflict across repeat families. PMID:32266012
Identification of Autophagy-Associated Biomarkers and Corresponding Regulatory Factors in the Progression of Colorectal Cancer. PMID:32265986
Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. PMID:32259481
Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogenic lncRNA that Interacts with HNRNPA2B1 and Regulates miR-106b Biogenesis. PMID:32246902
The Emerging Role of ncRNAs and RNA-Binding Proteins in Mitotic Apparatus Formation. PMID:32245090
A genomic and epigenomic atlas of prostate cancer in Asian populations. PMID:32238934
U1 snRNP regulates chromatin retention of noncoding RNAs. PMID:32238924
Tumor suppressor and oncogenic role of long non-coding RNAs in cancer. PMID:32232211
Genomic and Transcriptomic Analysis Identified Novel Putative Cassava lncRNAs Involved in Cold and Drought Stress. PMID:32231066
dbMTS: A comprehensive database of putative human microRNA target site SNVs and their functional predictions. PMID:32227657
Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells. PMID:32222775
Evidence of constraint in the 3D genome for trans-splicing in human cells. PMID:32221814
Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA. PMID:32220292
CLING: Candidate Cancer-Related lncRNA Prioritization via Integrating Multiple Biological Networks. PMID:32211391
DNA methylation disruption reshapes the hematopoietic differentiation landscape. PMID:32203468
An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2. PMID:32188783
RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells. PMID:32180230
MoAIMS: efficient software for detection of enriched regions of MeRIP-Seq. PMID:32171255
COMPSRA: a COMprehensive Platform for Small RNA-Seq data Analysis. PMID:32165660
Identification of lncRNA-associated differential subnetworks in oesophageal squamous cell carcinoma by differential co-expression analysis. PMID:32164040
Cystic renal-epithelial derived induced pluripotent stem cells from polycystic kidney disease patients. PMID:32163234
Beyond classic editing: innovative CRISPR approaches for functional studies of long non-coding RNA. PMID:32161809
Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors. PMID:32161105
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes. PMID:32157095
Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress. PMID:32156729
Differential expression analysis comparing EBV uninfected to infected human cell lines identifies induced non-micro small non-coding RNAs. PMID:32154466
The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage. PMID:32152280
MiR-7 reduces the BCSC subset by inhibiting XIST to modulate the miR-92b/Slug/ESA axis and inhibit tumor growth. PMID:32143670
Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data. PMID:32127534
Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons. PMID:32126975
Long Non-Coding RNA H19 Promotes Porcine Satellite Cell Differentiation by Interacting with TDP43. PMID:32121115
Inferring lncRNA Functional Similarity Based on Integrating Heterogeneous Network Data. PMID:32117916
PAX1 is essential for development and function of the human thymus. PMID:32111619
Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer. PMID:32111241
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. PMID:32109421
Candidate silencer elements for the human and mouse genomes. PMID:32103011
Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers. PMID:32086391
Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences. PMID:32084333
PVT1 Long Non-coding RNA in Gastrointestinal Cancer. PMID:32083000
A lncRNA survey finds increases in neuroprotective LINC-PINT in Parkinson's disease substantia nigra. PMID:32080970
Skeletal Muscle Regeneration in Advanced Diabetic Peripheral Neuropathy. PMID:32059624
Exploration of databases and methods supporting drug repurposing: a comprehensive survey. PMID:32055842
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity. PMID:32054838
Novel Mutation Hotspots within Non-Coding Regulatory Regions of the Chronic Lymphocytic Leukemia Genome. PMID:32051441
Derivation of trophoblast stem cells from naïve human pluripotent stem cells. PMID:32048992
Variations and expression features of CYP2D6 contribute to schizophrenia risk. PMID:32047265
Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq. PMID:32040509
CLEAR: coverage-based limiting-cell experiment analysis for RNA-seq. PMID:32039730
Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage. PMID:32029882
Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures. PMID:32029221
Integrative prediction of gene expression with chromatin accessibility and conformation data. PMID:32029002
Genomic basis for RNA alterations in cancer. PMID:32025019
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. PMID:32025015
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis. PMID:32024996
Combined burden and functional impact tests for cancer driver discovery using DriverPower. PMID:32024818
Genomic footprints of activated telomere maintenance mechanisms in cancer. PMID:32024817
Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma. PMID:32023450
Progress in understanding the relationship between long noncoding RNA and endometriosis. PMID:32021971
Characterization of the human GnRH neuron developmental transcriptome using a GNRH1-TdTomato reporter line in human pluripotent stem cells. PMID:31996360
Refgenie: a reference genome resource manager. PMID:31995185
Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. PMID:31992716
Functional and transcriptomic characterization of cisplatin-resistant AGS and MKN-28 gastric cancer cell lines. PMID:31990955
Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4. PMID:31988093
Effect of eleutheroside B1 on non‑coding RNAs and protein profiles of influenza A virus‑infected A549 cells. PMID:31985023
Single-cell transcriptomics from human pancreatic islets: sample preparation matters. PMID:31984226
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA. PMID:31980822
Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform. PMID:31961876
Up-regulated LINC01234 promotes non-small-cell lung cancer cell metastasis by activating VAV3 and repressing BTG2 expression. PMID:31959200
Epigenetic plasticity of enhancers in cancer. PMID:31944157
YB-3 substitutes YB-1 in global mRNA binding. PMID:31944153
Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor. PMID:31940495
Structural variation and its potential impact on genome instability: Novel discoveries in the EGFR landscape by long-read sequencing. PMID:31940362
Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin. PMID:31939706
Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro. PMID:31934351
miR-373 inhibits nasopharyngeal carcinoma cell migration and invasion by targeting MARCH5. PMID:31934093
Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages. PMID:31913118
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. PMID:31911677
Non-coding RNAs underlie genetic predisposition to breast cancer. PMID:31910864
Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells. PMID:31909251
When Long Noncoding Becomes Protein Coding. PMID:31907280
LINC01714 Enhances Gemcitabine Sensitivity by Modulating FOXO3 Phosphorylation in Cholangiocarcinoma. PMID:31902744
Uncovering Biological Factors That Regulate Hepatocellular Carcinoma Growth Using Patient-Derived Xenograft Assays. PMID:31899548
In silico identification of EP400 and TIA1 as critical transcription factors involved in human hepatocellular carcinoma relapse. PMID:31897208
Cellular and molecular characterization of multiplex autism in human induced pluripotent stem cell-derived neurons. PMID:31893020
Learning distributed representations of RNA and protein sequences and its application for predicting lncRNA-protein interactions. PMID:31890140
A network view of microRNA and gene interactions in different pathological stages of colon cancer. PMID:31888617
Discovering Rare Genes Contributing to Cancer Stemness and Invasive Potential by GBM Single-Cell Transcriptional Analysis. PMID:31888172
Circ_MDM2_000139, Circ_ATF2_001418, Circ_CDC25C_002079, and Circ_BIRC6_001271 Are Involved in the Functions of XAV939 in Non-Small Cell Lung Cancer. PMID:31885751
Small noncoding RNA discovery and profiling with sRNAtools based on high-throughput sequencing. PMID:31885040
Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research. PMID:31882946
Deep mixed model for marginal epistasis detection and population stratification correction in genome-wide association studies. PMID:31881907
Predicted Archaic 3D Genome Organization Reveals Genes Related to Head and Spinal Cord Separating Modern from Archaic Humans. PMID:31878147
Targeted sequencing of the LRRTM gene family in suicide attempters with bipolar disorder. PMID:31854516
Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma. PMID:31853539
A 10-year prediagnostic follow-up study shows that serum RNA signals are highly dynamic in lung carcinogenesis. PMID:31851411
RHPCG: a database of the Regulation of the Hippo Pathway in Cancer Genome. PMID:31848596
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania. PMID:31844061
The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas. PMID:31834371
A developmental landscape of 3D-cultured human pre-gastrulation embryos. PMID:31830756
Nonequilibrium Biophysical Processes Influence the Large-Scale Architecture of the Cell Nucleus. PMID:31818465
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A. PMID:31814998
GraphClust2: Annotation and discovery of structured RNAs with scalable and accessible integrative clustering. PMID:31808801
The distributions of protein coding genes within chromatin domains in relation to human disease. PMID:31805995
miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart. PMID:31801413
Subendothelial stiffness alters endothelial cell traction force generation while exerting a minimal effect on the transcriptome. PMID:31796790
Meglumine acridone acetate, the ionic salt of CMA and N-methylglucamine, induces apoptosis in human PBMCs via the mitochondrial pathway. PMID:31796757
Multimodal Long Noncoding RNA Interaction Networks: Control Panels for Cell Fate Specification. PMID:31796550
Causal association of type 2 diabetes with amyotrophic lateral sclerosis: new evidence from Mendelian randomization using GWAS summary statistics. PMID:31796040
A novel RNA sequencing-based risk score model to predict papillary thyroid carcinoma recurrence. PMID:31792675
LncDisAP: a computation model for LncRNA-disease association prediction based on multiple biological datasets. PMID:31787106
Translated Long Non-Coding Ribonucleic Acid ZFAS1 Promotes Cancer Cell Migration by Elevating Reactive Oxygen Species Production in Hepatocellular Carcinoma. PMID:31781169
Characterization of Hepatocellular Carcinoma Cell Lines Using a Fractionation-Then-Sequencing Approach Reveals Nuclear-Enriched HCC-Associated lncRNAs. PMID:31781161
Common DNA sequence variation influences 3-dimensional conformation of the human genome. PMID:31779666
Machine Learning Approaches for the Prioritization of Genomic Variants Impacting Pre-mRNA Splicing. PMID:31779139
Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age. PMID:31767861
DNA methylation aging clocks: challenges and recommendations. PMID:31767039
Recurrent somatic mutations reveal new insights into consequences of mutagenic processes in cancer. PMID:31765368
Midbrain microglia mediate a specific immunosuppressive response under inflammatory conditions. PMID:31757220
Long noncoding RNAs in lipid metabolism: literature review and conservation analysis across species. PMID:31752679
A single ChIP-seq dataset is sufficient for comprehensive analysis of motifs co-occurrence with MCOT package. PMID:31750523
The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact. PMID:31748536
Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease. PMID:31746734
Transposable element expression in tumors is associated with immune infiltration and increased antigenicity. PMID:31745090
Comparative genomic analysis of eutherian connexin genes. PMID:31729432
A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B-cell Acute Lymphoblastic Leukemia. PMID:31723839
Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias. PMID:31714939
LncTarD: a manually-curated database of experimentally-supported functional lncRNA-target regulations in human diseases. PMID:31713618
Immunological observations and transcriptomic analysis of trimester-specific full-term placentas from three Zika virus-infected women. PMID:31709049
ILF3 contributes to the establishment of the antiviral type I interferon program. PMID:31701124
Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution. PMID:31698782
Long-read sequencing reveals the complex splicing profile of the psychiatric risk gene CACNA1C in human brain. PMID:31695164
AIDE: annotation-assisted isoform discovery with high precision. PMID:31694868
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35. PMID:31690716
Improving single-cell transcriptome sequencing efficiency with a microfluidic phase-switch device. PMID:31688860
Differentiation of Long Non-Coding RNA and mRNA Expression Profiles in Male and Female Aedes albopictus. PMID:31681418
Enhancer LncRNAs Influence Chromatin Interactions in Different Ways. PMID:31681405
The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes. PMID:31676868
A multi-sample approach increases the accuracy of transcript assembly. PMID:31676772
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways. PMID:31672989
Systematic Discovery of Endogenous Human Ribonucleoprotein Complexes. PMID:31665645
Metabolic reprogramming associated with aggressiveness occurs in the G-CIMP-high molecular subtypes of IDH1mut lower grade gliomas. PMID:31665443
Double triage to identify poorly annotated genes in maize: The missing link in community curation. PMID:31658277
Comparative Genomics Analysis Reveals High Levels of Differential Retrotransposition among Primates from the Hominidae and the Cercopithecidae Families. PMID:31651947
Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. PMID:31649251
The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. PMID:31640799
Loss of Imprinting in Human Placentas Is Widespread, Coordinated, and Predicts Birth Phenotypes. PMID:31639821
Comprehensive RNA-Seq Data Analysis Identifies Key mRNAs and lncRNAs in Atrial Fibrillation. PMID:31632440
LncRNA LINC01116 Promotes Cancer Cell Proliferation, Migration And Invasion In Gastric Cancer By Positively Interacting With lncRNA CASC11. PMID:31632064
Identifying regulatory pathways of spleen tyrosine kinase expression in human basophils. PMID:31629804
A Balanced Translocation in Kallmann Syndrome Implicates a Long Noncoding RNA, RMST, as a GnRH Neuronal Regulator. PMID:31628846
Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. PMID:31626773
The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington's disease brain. PMID:31619230
Profiling of tRNA Halves and YRNA Fragments in Serum and Tissue From Oral Squamous Cell Carcinoma Patients Identify Key Role of 5' tRNA-Val-CAC-2-1 Half. PMID:31616639
DNA sequence-dependent chromatin architecture and nuclear hubs formation. PMID:31601866
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data. PMID:31601804
The U1 spliceosomal RNA is recurrently mutated in multiple cancers. PMID:31597163
An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations. PMID:31591557
LncRNA LUCAT1 as a novel prognostic biomarker for patients with papillary thyroid cancer. PMID:31591432
Long non-coding RNAs in cutaneous biology and proliferative skin diseases: Advances and perspectives. PMID:31588640
Realizing the potential of full-length transcriptome sequencing. PMID:31587638
Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer. PMID:31586988
Plasma extracellular vesicle microRNAs for pulmonary ground-glass nodules. PMID:31579436
SFTA1P, LINC00968, GATA6-AS1, TBX5-AS1, and FEZF1-AS1 are crucial long non-coding RNAs associated with the prognosis of lung squamous cell carcinoma. PMID:31579094
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies. PMID:31570896
Landscape of stimulation-responsive chromatin across diverse human immune cells. PMID:31570894
Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. PMID:31570892
c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program. PMID:31570496
Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma. PMID:31570490
Expression of microRNA in human retinal pigment epithelial cells following infection with Zaire ebolavirus. PMID:31570108
LNRLMI: Linear neighbour representation for predicting lncRNA-miRNA interactions. PMID:31568653
Crosstalk of mRNA, miRNA, lncRNA, and circRNA and Their Regulatory Pattern in Pulmonary Fibrosis. PMID:31561125
LINC01133 inhibits breast cancer invasion and metastasis by negatively regulating SOX4 expression through EZH2. PMID:31557401
Network-based method for drug target discovery at the isoform level. PMID:31554914
The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter. PMID:31551335
LINC00461 affects the survival of patients with renal cell carcinoma by acting as a competing endogenous RNA for microRNA‑942. PMID:31545458
Discovery of high-confidence human protein-coding genes and exons by whole-genome PhyloCSF helps elucidate 118 GWAS loci. PMID:31537640
Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3. PMID:31534498
Evolutionary and functional impact of common polymorphic inversions in the human genome. PMID:31530810
Sequence determinants of polyadenylation-mediated regulation. PMID:31530582
Expression of ZNF695 Transcript Variants in Childhood B-Cell Acute Lymphoblastic Leukemia. PMID:31527520
A comprehensive, multidisciplinary, precision medicine approach to discover effective therapy for an undiagnosed, progressive, fibroinflammatory disease. PMID:31520587
Gene expression profiling of single cells from archival tissue with laser-capture microdissection and Smart-3SEQ. PMID:31519740
Effect of hyperoside on cervical cancer cells and transcriptome analysis of differentially expressed genes. PMID:31516392
Possible Molecular Mechanisms for the Roles of MicroRNA-21 Played in Lung Cancer. PMID:31506038
Identifying targets for preventing epilepsy using systems biology of the human brain. PMID:31493467
A polygenic resilience score moderates the genetic risk for schizophrenia. PMID:31492941
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements. PMID:31492858
Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations. PMID:31484939
Comprehensive analysis of long noncoding RNA (lncRNA)-chromatin interactions reveals lncRNA functions dependent on binding diverse regulatory elements. PMID:31484726
PredLnc-GFStack: A Global Sequence Feature Based on a Stacked Ensemble Learning Method for Predicting lncRNAs from Transcripts. PMID:31484412
Graph Convolutional Network and Convolutional Neural Network Based Method for Predicting lncRNA-Disease Associations. PMID:31480350
NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements. PMID:31477927
Identification of lung-adenocarcinoma-related long non-coding RNAs by random walking on a competing endogenous RNA network. PMID:31475209
Getting the Entire Message: Progress in Isoform Sequencing. PMID:31475029
Long intergenic noncoding RNA profiles of pheochromocytoma and paraganglioma: A novel prognostic biomarker. PMID:31469413
Maximizing binary interactome mapping with a minimal number of assays. PMID:31467278
Long non-coding RNA LINC01225 promotes proliferation, invasion and migration of gastric cancer via Wnt/β-catenin signalling pathway. PMID:31460694
Modeling and analysis of RNA-seq data: a review from a statistical perspective. PMID:31456901
Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. PMID:31452935
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. PMID:31451708
Harnessing the tissue and plasma lncRNA-peptidome to discover peptide-based cancer biomarkers. PMID:31444383
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma-A Proof of Antigen Discovery Feasibility in Three Patients. PMID:31440238
The role of long non-coding RNAs in cardiac development and disease. PMID:31435517
Replication timing networks reveal a link between transcription regulatory circuits and replication timing control. PMID:31434679
Six-mRNA risk score system and nomogram constructed for patients with ovarian cancer. PMID:31423184
The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress. PMID:31417181
Application of the High-throughput TAB-Array for the Discovery of Novel 5-Hydroxymethylcytosine Biomarkers in Pancreatic Ductal Adenocarcinoma. PMID:31413874
EPIP: a novel approach for condition-specific enhancer-promoter interaction prediction. PMID:31410461
Whole genome and transcriptome sequencing of post-mortem cardiac tissues from sudden cardiac death victims identifies a gene regulatory variant in NEXN. PMID:31392414
Molecular architecture of lineage allocation and tissue organization in early mouse embryo. PMID:31391582
ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion. PMID:31391455
Applications of the Soil, Plant and Rumen Microbiomes in Pastoral Agriculture. PMID:31380386
Functional genetic variants can mediate their regulatory effects through alteration of transcription factor binding. PMID:31375681
Prediction of regulatory motifs from human Chip-sequencing data using a deep learning framework. PMID:31372637
A Comprehensive Study of Vesicular and Non-Vesicular miRNAs from a Volume of Cerebrospinal Fluid Compatible with Clinical Practice. PMID:31367240
Beyond sequencing: re-visiting annotations for PJL as a test case. PMID:31366397
HUPAN: a pan-genome analysis pipeline for human genomes. PMID:31366358
The long noncoding RNA MALAT1 predicts human pancreatic islet isolation quality. PMID:31361602
Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing. PMID:31360895
Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury. PMID:31356870
An expanded landscape of human long noncoding RNA. PMID:31350901
Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits. PMID:31345219
Predicting functional long non-coding RNAs validated by low throughput experiments. PMID:31345106
Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data. PMID:31344359
Eye in a Disk: eyeIntegration Human Pan-Eye and Body Transcriptome Database Version 1.0. PMID:31343654
Benchmark and integration of resources for the estimation of human transcription factor activities. PMID:31340985
Impact of sequencing depth and technology on de novo RNA-Seq assembly. PMID:31337347
Long Non-Coding RNA Function in CD4+ T Cells: What We Know and What Next? PMID:31336952
Identification of DNA motifs that regulate DNA methylation. PMID:31334813
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease. PMID:31330134
Simultaneous RNA purification and size selection using on-chip isotachophoresis with an ionic spacer. PMID:31328753
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. PMID:31320637
NEAT1 is overexpressed in Parkinson's disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress. PMID:31311324
Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Peanut. PMID:31311183
Vitamin D differentially regulates colon stem cells in patient-derived normal and tumor organoids. PMID:31306552
FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation. PMID:31291575
Correlations between Genetic Polymorphisms in Long Non-Coding RNA PRNCR1 and Gastric Cancer Risk in a Korean Population. PMID:31288430
Systematic discovery of conservation states for single-nucleotide annotation of the human genome. PMID:31286065
The construction and analysis of the aberrant lncRNA-miRNA-mRNA network in non-small cell lung cancer. PMID:31285869
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease. PMID:31283791
Predicting drug-free remission in rheumatoid arthritis: A prospective interventional cohort study. PMID:31280933
Leukocyte transcriptional signatures dependent on LPS dosage in human endotoxemia. PMID:31280495
Uncovering biomarker genes with enriched classification potential from Hallmark gene sets. PMID:31278367
TNF-α Differentially Regulates Cell Cycle Genes in Promyelocytic and Granulocytic HL-60/S4 Cells. PMID:31263060
Detecting the long non‑coding RNA signature related to spinal cord ependymal tumor subtype using a genome‑wide methylome analysis approach. PMID:31257484
Conditional Activation of NF-κB Inducing Kinase (NIK) in the Osteolineage Enhances Both Basal and Loading-Induced Bone Formation. PMID:31246323
3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome. PMID:31240104
Integration of CLIP experiments of RNA-binding proteins: a novel approach to predict context-dependent splicing factors from transcriptomic data. PMID:31238884
Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA. PMID:31237235
Molecular Traits of Long Non-protein Coding RNAs from Diverse Plant Species Show Little Evidence of Phylogenetic Relationships. PMID:31235560
Genome-Wide Analysis of Long Non-Coding RNA Profiles in Canine Oral Melanomas. PMID:31234577
PhenoScanner V2: an expanded tool for searching human genotype-phenotype associations. PMID:31233103
Accumulating computational resource usage of genomic data analysis workflow to optimize cloud computing instance selection. PMID:31222199
Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells. PMID:31216472
p73 regulates epidermal wound healing and induced keratinocyte programming. PMID:31216312
Phytochemicals as Modulators of Long Non-Coding RNAs and Inhibitors of Cancer-Related Carbonic Anhydrases. PMID:31208095
TOX is a critical regulator of tumour-specific T cell differentiation. PMID:31207604
Evolutionary perspectives on polygenic selection, missing heritability, and GWAS. PMID:31201529
Computational Methods for Mapping, Assembly and Quantification for Coding and Non-coding Transcripts. PMID:31193391
Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells. PMID:31191614
LncRNA-Disease Association Prediction Using Two-Side Sparse Self-Representation. PMID:31191605
LncRRIsearch: A Web Server for lncRNA-RNA Interaction Prediction Integrated With Tissue-Specific Expression and Subcellular Localization Data. PMID:31191601
RNA sequencing uncovers the key long non-coding RNAs and potential molecular mechanism contributing to XAV939-mediated inhibition of non-small cell lung cancer. PMID:31186710
Codon usage optimization in pluripotent embryonic stem cells. PMID:31174582
Comprehensive Characterization of the Human Endogenous Retrovirus HERV-K(HML-6) Group: Overview of Structure, Phylogeny, and Contribution to the Human Genome. PMID:31167914
Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation. PMID:31164154
Integrative Analysis of Somatic Mutations in Non-coding Regions Altering RNA Secondary Structures in Cancer Genomes. PMID:31160636
Haplotype-aware diplotyping from noisy long reads. PMID:31159868
Bridging the gap between reference and real transcriptomes. PMID:31159855
Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks. PMID:31159744
CircRNA-100338 Is Associated With mTOR Signaling Pathway and Poor Prognosis in Hepatocellular Carcinoma. PMID:31157168
Novel Approaches in Ovarian Cancer Research against Heterogeneity, Late Diagnosis, Drug Resistance, and Transcoelomic Metastases. PMID:31146417
Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. PMID:31133750
Genetic analyses of human fetal retinal pigment epithelium gene expression suggest ocular disease mechanisms. PMID:31123710
MetaDome: Pathogenicity analysis of genetic variants through aggregation of homologous human protein domains. PMID:31116477
Genetics of heart rate in heart failure patients (GenHRate). PMID:31113495
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. PMID:31092926
Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes. PMID:31078526
A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins. PMID:31078383
Tissue-specific genes as an underutilized resource in drug discovery. PMID:31076736
Large-scale in-silico identification of a tumor-specific antigen pool for targeted immunotherapy in triple-negative breast cancer. PMID:31069014
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk. PMID:31064983
Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines. PMID:31061680
A five lncRNA signature for prognosis prediction in hepatocellular carcinoma. PMID:31059056
Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis. PMID:31053723
Identification and Quantification of Proteoforms by Mass Spectrometry. PMID:31050378
EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences. PMID:31045217
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons. PMID:31042469
ClinOmicsTrailbc: a visual analytics tool for breast cancer treatment stratification. PMID:31038669
Complement C7 is a novel risk gene for Alzheimer's disease in Han Chinese. PMID:31032141
A Panel of 12-lncRNA Signature Predicts Survival of Pancreatic Adenocarcinoma. PMID:31031865
Targeted, High-Resolution RNA Sequencing of Non-coding Genomic Regions Associated With Neuropsychiatric Functions. PMID:31031799
PseudoFuN: Deriving functional potentials of pseudogenes from integrative relationships with genes and microRNAs across 32 cancers. PMID:31029062
African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations. PMID:31023338
RNA Sequencing Analyses of Gene Expression during Epstein-Barr Virus Infection of Primary B Lymphocytes. PMID:31019051
Transcriptome Alterations in Liver Metastases of Colorectal Cancer After Acquired Resistance to Cetuximab. PMID:31018951
An integrated analysis reveals the oncogenic function of lncRNA LINC00511 in human ovarian cancer. PMID:31016892
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. PMID:31015400
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF. PMID:31014355
Applications of ENCODE data to Systematic Analyses via Data Integration. PMID:31011690
BayesPI-BAR2: A New Python Package for Predicting Functional Non-coding Mutations in Cancer Patient Cohorts. PMID:31001324
NF-κB Signaling and IL-4 Signaling Regulate SATB1 Expression via Alternative Promoter Usage During Th2 Differentiation. PMID:31001272
Evidence for an oncogenic role of HOXC6 in human non-small cell lung cancer. PMID:30993034
Prediction of Long Non-Coding RNAs Based on Deep Learning. PMID:30987229
Integrated Transcriptomic and Proteomic Analysis of Primary Human Umbilical Vein Endothelial Cells. PMID:30983154
Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs. PMID:30982597
Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain. PMID:30977723
Pan-cancer analysis on microRNA-associated gene activation. PMID:30956173
exceRpt: A Comprehensive Analytic Platform for Extracellular RNA Profiling. PMID:30956140
High resolution discovery of chromatin interactions. PMID:30953075
PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data. PMID:30951143
ADAR1 promotes robust hypoxia signaling via distinct regulation of multiple HIF-1α-inhibiting factors. PMID:30948460
TranscriptAchilles: a genome-wide platform to predict isoform biomarkers of gene essentiality in cancer. PMID:30942869
The lncRNA Neat1 promotes activation of inflammasomes in macrophages. PMID:30940803
Transposable elements drive widespread expression of oncogenes in human cancers. PMID:30926969
Electrotaxis of Glioblastoma and Medulloblastoma Spheroidal Aggregates. PMID:30926929
Combinatorial interactions of genetic variants in human cardiomyopathy. PMID:30923642
FactorNet: A deep learning framework for predicting cell type specific transcription factor binding from nucleotide-resolution sequential data. PMID:30922998
Diagnosis of fusion genes using targeted RNA sequencing. PMID:30918253
Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune Response. PMID:30917313
Integrative transcriptomic analysis suggests new autoregulatory splicing events coupled with nonsense-mediated mRNA decay. PMID:30916337
Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data. PMID:30914061
Contribution of ultrarare variants in mTOR pathway genes to sporadic focal epilepsies. PMID:30911571
Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line. PMID:30894224
Transcriptome Analysis of the Human Tibial Nerve Identifies Sexually Dimorphic Expression of Genes Involved in Pain, Inflammation, and Neuro-Immunity. PMID:30890918
The Proteogenomic Landscape of Curable Prostate Cancer. PMID:30889379
HOXC6 promotes migration, invasion and proliferation of esophageal squamous cell carcinoma cells via modulating expression of genes involved in malignant phenotypes. PMID:30886783
Genetic Association of Olanzapine Treatment Response in Han Chinese Schizophrenia Patients. PMID:30886581
Long Noncoding RNA MPRL Promotes Mitochondrial Fission and Cisplatin Chemosensitivity via Disruption of Pre-miRNA Processing. PMID:30885939
Evaluating and sharing global genetic ancestry in biomedical datasets. PMID:30869786
Liquid Biopsies in Lung Cancer: Four Emerging Technologies and Potential Clinical Applications. PMID:30866571
Genome-wide analysis of long non-coding RNA expression profile in porcine circovirus 2-infected intestinal porcine epithelial cell line by RNA sequencing. PMID:30863688
Correlations of lncRNAs with cervical lymph node metastasis and prognosis of papillary thyroid carcinoma. PMID:30863094
Drug repositioning in epilepsy reveals novel antiseizure candidates. PMID:30847362
The cellular landscape of mid-size noncoding RNA. PMID:30843375
svist4get: a simple visualization tool for genomic tracks from sequencing experiments. PMID:30841857
Multi-Omics Approaches to Study Long Non-coding RNA Function in Atherosclerosis. PMID:30838214
Integrative Analysis Reveals Key Circular RNA in Atrial Fibrillation. PMID:30838031
Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP. PMID:30837873
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways. PMID:30837866
Shared and unique genomic structural variants of different histological components within testicular germ cell tumours identified with mate pair sequencing. PMID:30837548
Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression. PMID:30837461
Revealing Gene Function and Transcription Relationship by Reconstructing Gene-Level Chromatin Interaction. PMID:30828411
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. PMID:30820047
Circular RNA expression profiles in neonatal rats following hypoxic-ischemic brain damage. PMID:30816430
RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4. PMID:30814490
BGFE: A Deep Learning Model for ncRNA-Protein Interaction Predictions Based on Improved Sequence Information. PMID:30813451
Identification of lncRNA TRPM2-AS/miR-140-3p/PYCR1 axis's proliferates and anti-apoptotic effect on breast cancer using co-expression network analysis. PMID:30810442
Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages. PMID:30809020
SELER: a database of super-enhancer-associated lncRNA- directed transcriptional regulation in human cancers. PMID:30806704
New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulation. PMID:30782641
CVm6A: A Visualization and Exploration Database for m⁶As in Cell Lines. PMID:30781586
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response. PMID:30778059
Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia. PMID:30773278
Role of Noncoding RNAs in the Pathogenesis of Abdominal Aortic Aneurysm. PMID:30763215
Epigenetic findings in periodontitis in UK twins: a cross-sectional study. PMID:30760334
Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer. PMID:30755618
Histone deacetylase inhibitors induce complex host responses that contribute to differential potencies of these compounds in HIV reactivation. PMID:30745362
PUMILIO hyperactivity drives premature aging of Norad-deficient mice. PMID:30735131
Proposal for Modification of Cahan's Criteria Utilizing Molecular Genetic Analyses for Cases without Baseline Histopathology: A Unique Method Applicable to Primary Radiosurgery. PMID:30733895
RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types. PMID:30726743
RNA-Seq profiling in peripheral blood mononuclear cells of amyotrophic lateral sclerosis patients and controls. PMID:30720798
The circRNA-microRNA code: emerging implications for cancer diagnosis and treatment. PMID:30719845
Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1. PMID:30718900
The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region. PMID:30718669
Identification of the targets of hematoporphyrin derivative in lung adenocarcinoma using integrated network analysis. PMID:30717818
Prohibitin: A hypothetical target for sex-based new therapeutics for metabolic and immune diseases. PMID:30717609
Bioinformatics analysis to identify the key genes affecting the progression and prognosis of hepatocellular carcinoma. PMID:30705088
Generative modeling of multi-mapping reads with mHi-C advances analysis of Hi-C studies. PMID:30702424
Detection of RNA-DNA binding sites in long noncoding RNAs. PMID:30698727
GARFIELD classifies disease-relevant genomic features through integration of functional annotations with association signals. PMID:30692680
EnhancerDB: a resource of transcriptional regulation in the context of enhancers. PMID:30689845
High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity. PMID:30683753
Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens. PMID:30683138
Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. PMID:30674564
Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands. PMID:30664630
Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients. PMID:30662003
Propofol Suppresses Proinflammatory Cytokine Production by Increasing ABCA1 Expression via Mediation by the Long Noncoding RNA LOC286367. PMID:30647536
pblat: a multithread blat algorithm speeding up aligning sequences to genomes. PMID:30646844
Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability. PMID:30643296
Invited Review: Long non-coding RNAs: important regulators in the development, function and disorders of the central nervous system. PMID:30636336
The Circulating Transcriptome as a Source of Biomarkers for Melanoma. PMID:30634628
Treatment of two mitochondrial disease patients with a combination of febuxostat and inosine that enhances cellular ATP. PMID:30631120
Accurate prediction of cell type-specific transcription factor binding. PMID:30630522
West Nile Virus-Inclusive Single-Cell RNA Sequencing Reveals Heterogeneity in the Type I Interferon Response within Single Cells. PMID:30626670
Interpreting Non-coding Genetic Variation in Multiple Sclerosis Genome-Wide Associated Regions. PMID:30619471
The Role of Histone Methyltransferases and Long Non-coding RNAs in the Regulation of T Cell Fate Decisions. PMID:30619315
Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases. PMID:30610612
Isolation and genome-wide characterization of cellular DNA:RNA triplex structures. PMID:30605520
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. PMID:30604766
Balancing yield, purity and practicality: a modified differential ultracentrifugation protocol for efficient isolation of small extracellular vesicles from human serum. PMID:30604646
Oligomeric proanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cells. PMID:30596962
A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela. PMID:30596671
Discerning novel splice junctions derived from RNA-seq alignment: a deep learning approach. PMID:30591034
Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs. PMID:30587508
Pathogenicity and selective constraint on variation near splice sites. PMID:30587507
Current perspectives in assessing humoral immunity after measles vaccination. PMID:30585753
RNA element discovery from germ cell to blastocyst. PMID:30576549
Generation of an immortalized human choroid endothelial cell line (iChEC-1) using an endothelial cell specific promoter. PMID:30571950
Anchor: trans-cell type prediction of transcription factor binding sites. PMID:30567711
Measures of co-expression for improved function prediction of long non-coding RNAs. PMID:30567492
A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra. PMID:30566875
Relative impact of indels versus SNPs on complex disease. PMID:30565766
An evolutionary framework for measuring epigenomic information and estimating cell-type-specific fitness consequences. PMID:30559490
Co-expression of long non-coding RNAs and autism risk genes in the developing human brain. PMID:30547845
Long noncoding RNAs of single hematopoietic stem and progenitor cells in healthy and dysplastic human bone marrow. PMID:30545929
Transcriptome and epigenome landscape of human cortical development modeled in organoids. PMID:30545853
Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder. PMID:30545852
Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals. PMID:30545422
Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescence. PMID:30528453
Bi-allelic TMEM94 Truncating Variants Are Associated with Neurodevelopmental Delay, Congenital Heart Defects, and Distinct Facial Dysmorphism. PMID:30526868
Rapid reversible changes in compartments and local chromatin organization revealed by hyperosmotic shock. PMID:30523037
The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage. PMID:30520728
Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity. PMID:30518766
Interactome determination of a Long Noncoding RNA implicated in Embryonic Stem Cell Self-Renewal. PMID:30514857
Transcript- and protein-level analyses of the response of human eosinophils to glucocorticoids. PMID:30512017
Multifocal Versus Conventional Unifocal Diverticulitis: A Comparison of Clinical and Transcriptomic Characteristics. PMID:30511196
OUTRIDER: A Statistical Method for Detecting Aberrantly Expressed Genes in RNA Sequencing Data. PMID:30503520
CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise. PMID:30486838
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. PMID:30478444
Pooled extracellular receptor-ligand interaction screening using CRISPR activation. PMID:30477585
SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations. PMID:30477433
MIR sequences recruit zinc finger protein ZNF768 to expressed genes. PMID:30476274
Long non-coding RNAs in hematological malignancies: translating basic techniques into diagnostic and therapeutic strategies. PMID:30466456
Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity. PMID:30462643
BPLLDA: Predicting lncRNA-Disease Associations Based on Simple Paths With Limited Lengths in a Heterogeneous Network. PMID:30459803
ASGAL: aligning RNA-Seq data to a splicing graph to detect novel alternative splicing events. PMID:30458725
CARM1 methylates MED12 to regulate its RNA-binding ability. PMID:30456381
Widespread roles of enhancer-like transposable elements in cell identity and long-range genomic interactions. PMID:30455182
Insights into mammalian transcription control by systematic analysis of ChIP sequencing data. PMID:30453943
Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression. PMID:30449622
RNAct: Protein-RNA interaction predictions for model organisms with supporting experimental data. PMID:30445601
Splicing of long non-coding RNAs primarily depends on polypyrimidine tract and 5' splice-site sequences due to weak interactions with SR proteins. PMID:30445574
PAVOOC: designing CRISPR sgRNAs using 3D protein structures and functional domain annotations. PMID:30445568
Micro-Inversions In Human Cancer Genomes. PMID:30440635
Expression of mitochondrial dysfunction-related genes and pathways in paclitaxel-induced peripheral neuropathy in breast cancer survivors. PMID:30426838
Non-coding RNAome of RPE cells under oxidative stress suggests unknown regulative aspects of Retinitis pigmentosa etiopathogenesis. PMID:30413775
Ongoing human chromosome end extension revealed by analysis of BioNano and nanopore data. PMID:30413723
The DEK Oncoprotein Functions in Ovarian Cancer Growth and Survival. PMID:30412857
A Potential Competitive Endogenous RNA Pathway Involved in Chronic Spinal Cord Injury. PMID:30411720
FusionGDB: fusion gene annotation DataBase. PMID:30407583
Update of the FANTOM web resource: expansion to provide additional transcriptome atlases. PMID:30407557
Lnc2Cancer v2.0: updated database of experimentally supported long non-coding RNAs in human cancers. PMID:30407549
The UCSC Genome Browser database: 2019 update. PMID:30407534
WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA. PMID:30404245
Localizing and Classifying Adaptive Targets with Trend Filtered Regression. PMID:30398642
Longitudinal personal DNA methylome dynamics in a human with a chronic condition. PMID:30397358
A Prognostic Signature for Lower Grade Gliomas Based on Expression of Long Non-Coding RNAs. PMID:30392137
A phylogenomic study quantifies competing mechanisms for pseudogenization in prokaryotes-The Mycobacterium leprae case. PMID:30383852
Improved Macaca fascicularis gene annotation reveals evolution of gene expression profiles in multiple tissues. PMID:30382841
LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse. PMID:30380072
Whole-Genome Alignment and Comparative Annotation. PMID:30379572
Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus. PMID:30373810
LNCipedia 5: towards a reference set of human long non-coding RNAs. PMID:30371849
DUXAP8, a pseudogene derived lncRNA, promotes growth of pancreatic carcinoma cells by epigenetically silencing CDKN1A and KLF2. PMID:30367681
Cancer type prediction based on copy number aberration and chromatin 3D structure with convolutional neural networks. PMID:30367576
CircRNA-associated ceRNA network reveals ErbB and Hippo signaling pathways in hypopharyngeal cancer. PMID:30365065
EWAS Atlas: a curated knowledgebase of epigenome-wide association studies. PMID:30364969
Discordant roles for FGF ligands in lung branching morphogenesis between human and mouse. PMID:30357827
GENCODE reference annotation for the human and mouse genomes. PMID:30357393
CORUM: the comprehensive resource of mammalian protein complexes-2019. PMID:30357367
Genome-wide map of human and mouse transcription factor binding sites aggregated from ChIP-Seq data. PMID:30352610
Deleterious variation shapes the genomic landscape of introgression. PMID:30346959
From De Novo to "De Nono": The Majority of Novel Protein-Coding Genes Identified with Phylostratigraphy Are Old Genes or Recent Duplicates. PMID:30346517
Bridging Synaptic and Epigenetic Maintenance Mechanisms of the Engram. PMID:30344478
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health. PMID:30342560
SeqOthello: querying RNA-seq experiments at scale. PMID:30340508
Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial. PMID:30340504
Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells. PMID:30337371
Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury. PMID:30335683
PopHumanScan: the online catalog of human genome adaptation. PMID:30335169
Long noncoding RNA NBAT1 inhibits autophagy via suppression of ATG7 in non-small cell lung cancer. PMID:30323972
Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells. PMID:30320766
Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity. PMID:30311912
New players in chronic lung disease identified at the European Respiratory Society International Congress in Paris 2018: from microRNAs to extracellular vesicles. PMID:30310685
Thyroid hormone signaling specifies cone subtypes in human retinal organoids. PMID:30309916
Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: A prospective observational study. PMID:30308005
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism. PMID:30305631
Expression analysis of lncRNA AK370814 involved in the barley vitamin B6 salvage pathway under salinity. PMID:30298351
Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control. PMID:30297808
Shark genomes provide insights into elasmobranch evolution and the origin of vertebrates. PMID:30297745
Long non-coding RNA AFAP1-AS1 plays an oncogenic role in promoting cell migration in non-small cell lung cancer. PMID:30293090
Repurposing of promoters and enhancers during mammalian evolution. PMID:30287902
Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel. PMID:30279960
Long Noncoding RNA Signature and Disease Outcome in Estrogen Receptor-Positive Breast Cancer Patients Treated with Tamoxifen. PMID:30275856
Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease. PMID:30275566
Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci. PMID:30275530
New insights into the cellular temporal response to proteostatic stress. PMID:30272558
MiPanda: A Resource for Analyzing and Visualizing Next-Generation Sequencing Transcriptomics Data. PMID:30268942
Human genes: Time to follow the roads less traveled? PMID:30256779
The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells. PMID:30253781
Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing data. PMID:30243491
A differential host response to viral infection defines a subset of earlier-onset diverticulitis patients. PMID:30240468
POSTAR2: deciphering the post-transcriptional regulatory logics. PMID:30239819
Identifying core biological processes distinguishing human eye tissues with precise systems-level gene expression analyses and weighted correlation networks. PMID:30239781
The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities. PMID:30239724
Integrating hypertension phenotype and genotype with hybrid non-negative matrix factorization. PMID:30239588
New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action. PMID:30238005
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. PMID:30232453
Transcriptional fates of human-specific segmental duplications in brain. PMID:30228200
Genome-wide identification of tissue-specific long non-coding RNA in three farm animal species. PMID:30227846
Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease. PMID:30224808
Insights into the Influence of Specific Splicing Events on the Structural Organization of LRRK2. PMID:30223621
lncSLdb: a resource for long non-coding RNA subcellular localization. PMID:30219837
A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer. PMID:30218018
A pan-cancer atlas of cancer hallmark-associated candidate driver lncRNAs. PMID:30216655
Beyond the 3'UTR binding-microRNA-induced protein truncation via DNA binding. PMID:30214689
Refined RIP-seq protocol for epitranscriptome analysis with low input materials. PMID:30212448
The genetic basis and cell of origin of mixed phenotype acute leukaemia. PMID:30209392
Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms. PMID:30202060
Long noncoding RNA LERFS negatively regulates rheumatoid synovial aggression and proliferation. PMID:30198906
Targeting the IGF1R Pathway in Breast Cancer Using Antisense lncRNA-Mediated Promoter cis Competition. PMID:30195750
Characterisation and functional predictions of canine long non-coding RNAs. PMID:30194329
Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses. PMID:30190514
ZFAS1: a novel tumor-related long non-coding RNA. PMID:30186041
Pairs of Adjacent Conserved Noncoding Elements Separated by Conserved Genomic Distances Act as Cis-Regulatory Units. PMID:30184074
Integration of gene interaction information into a reweighted random survival forest approach for accurate survival prediction and survival biomarker discovery. PMID:30181543
Discovering lncRNA mediated sponge interactions in breast cancer molecular subtypes. PMID:30180792
RibORF: Identifying Genome-Wide Translated Open Reading Frames Using Ribosome Profiling. PMID:30178897
Transcriptomic analysis reveals key lncRNAs associated with ribosomal biogenesis and epidermis differentiation in head and neck squamous cell carcinoma. PMID:30178634
Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice. PMID:30177572
Long non-coding RNAs in the failing heart and vasculature. PMID:30175285
Molecular mechanism of activated T cells in breast cancer. PMID:30174439
ANNOgesic: a Swiss army knife for the RNA-seq based annotation of bacterial/archaeal genomes. PMID:30169674
High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs. PMID:30165668
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response. PMID:30158112
Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions. PMID:30157915
Mechanisms of Huangqi Decoction Granules () on Hepatitis B Cirrhosis Patients Based on RNA-Sequencing. PMID:30155678
Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler. PMID:30154186
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space. PMID:30150718
Genome-wide identification of clusters of predicted microRNA binding sites as microRNA sponge candidates. PMID:30142196
Long Non-Coding RNAs Guide the Fine-Tuning of Gene Regulation in B-Cell Development and Malignancy. PMID:30134619
Dysregulation of lncRNAs GM5524 and GM15645 involved in high‑glucose‑induced podocyte apoptosis and autophagy in diabetic nephropathy. PMID:30132544
Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq. PMID:30125121
Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer. PMID:30121958
Intron retention is a source of neoepitopes in cancer. PMID:30114007
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. PMID:30108311
Human proteins that interact with RNA/DNA hybrids. PMID:30108179
Risk assessment model constructed by differentially expressed lncRNAs for the prognosis of glioma. PMID:30106138
Identification of LINC01279 as a cell cycle‑associated long non‑coding RNA in endometriosis with GBA analysis. PMID:30106115
The landscape of the A-to-I RNA editome from 462 human genomes. PMID:30104667
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding. PMID:30097539
Curating Clinically Relevant Transcripts for the Interpretation of Sequence Variants. PMID:30096381
iMapSplice: Alleviating reference bias through personalized RNA-seq alignment. PMID:30096157
Bioinformatics-based analysis of the involvement of AC005550.3, RP11-415D17.3, and RP1-140K8.5 in homocysteine-induced vascular endothelial injury. PMID:30093949
LncFinder: an integrated platform for long non-coding RNA identification utilizing sequence intrinsic composition, structural information and physicochemical property. PMID:30084867
Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data. PMID:30083469
KDM5 histone demethylases repress immune response via suppression of STING. PMID:30080846
The Long Noncoding RNA Landscape in Amygdala Tissues from Schizophrenia Patients. PMID:30077719
Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer. PMID:30069443
Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis. PMID:30061742
exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes. PMID:30053265
Mobile elements contribute to the uniqueness of human genome with 15,000 human-specific insertions and 14 Mbp sequence increase. PMID:30052927
PausePred and Rfeet: webtools for inferring ribosome pauses and visualizing footprint density from ribosome profiling data. PMID:30049792
Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. PMID:30046111
A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma. PMID:30042422
Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT. PMID:30042172
Comprehensive map of age-associated splicing changes across human tissues and their contributions to age-associated diseases. PMID:30026530
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa. PMID:30021804
The Role of Long Non-coding RNAs in the Pathogenesis of RA, SLE, and SS. PMID:30018955
An Evolutionary Mechanism for the Generation of Competing RNA Structures Associated with Mutually Exclusive Exons. PMID:30018239
Matataki: an ultrafast mRNA quantification method for large-scale reanalysis of RNA-Seq data. PMID:30012088
Cancerin: A computational pipeline to infer cancer-associated ceRNA interaction networks. PMID:30011266
Genome-wide association study: Exploring the genetic basis for responsiveness to ketogenic dietary therapies for drug-resistant epilepsy. PMID:30009487
Comparative genomic analysis of eutherian adiponectin genes. PMID:30003153
Downregulation of lncRNA OGFRP1 inhibits hepatocellular carcinoma progression by AKT/mTOR and Wnt/β-catenin signaling pathways. PMID:29997441
Prioritization and functional assessment of noncoding variants associated with complex diseases. PMID:29996888
A deep recurrent neural network discovers complex biological rules to decipher RNA protein-coding potential. PMID:29986088
Identification of transcribed protein coding sequence remnants within lincRNAs. PMID:29986053
Mettl1/Wdr4-Mediated m7G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation. PMID:29983320
Loose ends: almost one in five human genes still have unresolved coding status. PMID:29982784
Clinker: visualizing fusion genes detected in RNA-seq data. PMID:29982439
Principles for targeting RNA with drug-like small molecules. PMID:29977051
Consensus molecular subtype classification of colorectal adenomas. PMID:29968252
Extracellular vesicles in DLBCL provide abundant clues to aberrant transcriptional programming and genomic alterations. PMID:29967128
Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line. PMID:29954844
Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria. PMID:29950443
COSSMO: predicting competitive alternative splice site selection using deep learning. PMID:29949959
Evidence for plant-derived xenomiRs based on a large-scale analysis of public small RNA sequencing data from human samples. PMID:29949574
Platforms for Investigating LncRNA Functions. PMID:29945466
Ribosome elongating footprints denoised by wavelet transform comprehensively characterize dynamic cellular translation events. PMID:29945224
Toward predictive R-loop computational biology: genome-scale prediction of R-loops reveals their association with complex promoter structures, G-quadruplexes and transcriptionally active enhancers. PMID:29945198
Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury. PMID:29941548
Exploring the functional impact of alternative splicing on human protein isoforms using available annotation sources. PMID:29931155
Germline genetic variants were interactively associated with somatic alterations in gastric cancer. PMID:29923336
Identification of differential expressed lncRNAs in human thyroid cancer by a genome-wide analyses. PMID:29923329
Identifying autophagy gene-associated module biomarkers through construction and analysis of an autophagy-mediated ceRNA‑ceRNA interaction network in colorectal cancer. PMID:29916526
In silico read normalization using set multi-cover optimization. PMID:29912280
Integrative Analysis of Dysregulated lncRNA-Associated ceRNA Network Reveals Functional lncRNAs in Gastric Cancer. PMID:29912172
Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. PMID:29895819
Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells. PMID:29893754
Multi-ethnic genome-wide association study for atrial fibrillation. PMID:29892015
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. PMID:29891976
Comparative Annotation Toolkit (CAT)-simultaneous clade and personal genome annotation. PMID:29884752
Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. PMID:29883787
High-resolution comparative analysis of great ape genomes. PMID:29880660
Chromatin Landscape Distinguishes the Genomic Loci of Hundreds of Androgen-Receptor-Associated LincRNAs From the Loci of Non-associated LincRNAs. PMID:29875794
Comprehensive comparative analysis of 5'-end RNA-sequencing methods. PMID:29867192
Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy. PMID:29861391
A Deep Learning Framework for Robust and Accurate Prediction of ncRNA-Protein Interactions Using Evolutionary Information. PMID:29858068
Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. PMID:29855537
Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer. PMID:29853643
Computational analysis of ribonomics datasets identifies long non-coding RNA targets of γ-herpesviral miRNAs. PMID:29846699
From genome-wide associations to candidate causal variants by statistical fine-mapping. PMID:29844615
Identification and analysis of ribosome-associated lncRNAs using ribosome profiling data. PMID:29843593
Analysis of the androgen receptor-regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression. PMID:29808028
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation. PMID:29802342
Soluble inflammatory mediators induce transcriptional re-organization that is independent of dna methylation changes in cultured human chorionic villous trophoblasts. PMID:29800761
Towards a complete map of the human long non-coding RNA transcriptome. PMID:29795125
Non-coding RNAs in Various Stages of Liver Disease Leading to Hepatocellular Carcinoma: Differential Expression of miRNAs, piRNAs, lncRNAs, circRNAs, and sno/mt-RNAs. PMID:29789629
Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells. PMID:29789566
Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing. PMID:29788454
LnChrom: a resource of experimentally validated lncRNA-chromatin interactions in human and mouse. PMID:29788225
Deep Surveying of the Transcriptional and Alternative Splicing Signatures for Decidual CD8+ T Cells at the First Trimester of Human Healthy Pregnancy. PMID:29780389
A long non-coding RNA signature for predicting survival in patients with colorectal cancer. PMID:29774095
GWAS4D: multidimensional analysis of context-specific regulatory variant for human complex diseases and traits. PMID:29771388
Tumor-associated intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation. PMID:29769310
Influenza Virus Mounts a Two-Pronged Attack on Host RNA Polymerase II Transcription. PMID:29768209
Prediction of enhancer-promoter interactions via natural language processing. PMID:29764360
Identification of a 5‑lncRNA signature‑based risk scoring system for survival prediction in colorectal cancer. PMID:29749517
Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma. PMID:29749396
Regulation of osteogenesis by long noncoding RNAs: An epigenetic mechanism contributing to bone formation. PMID:29745821
An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer. PMID:29744254
MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches. PMID:29739426
Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens. PMID:29738525
Functional Characterization of the Osteoarthritis Genetic Risk Residing at ALDH1A2 Identifies rs12915901 as a Key Target Variant. PMID:29732726
Deciphering the roles of lncRNAs in breast development and disease. PMID:29732012
MSIQ: JOINT MODELING OF MULTIPLE RNA-SEQ SAMPLES FOR ACCURATE ISOFORM QUANTIFICATION. PMID:29731954
RNA editing in nascent RNA affects pre-mRNA splicing. PMID:29724793
Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis. PMID:29719633
The fractured landscape of RNA-seq alignment: the default in our STARs. PMID:29718481
Relapse pathway of glioblastoma revealed by single-cell molecular analysis. PMID:29718126
FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer-promoter map. PMID:29716618
An Osteoporosis Risk SNP at 1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expression via Long-Range Loop Formation. PMID:29706346
Bayesian nonparametric discovery of isoforms and individual specific quantification. PMID:29703885
Predicting gene structure changes resulting from genetic variants via exon definition features. PMID:29701825
An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder. PMID:29700473
A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma. PMID:29700321
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies. PMID:29695774
Identification of differential expression lncRNAs in gastric cancer using transcriptome sequencing and bioinformatics analyses. PMID:29693709
The exon-intron gene structure upstream of the initiation codon predicts translation efficiency. PMID:29684192
Mechanistic insights into anticancer properties of oligomeric proanthocyanidins from grape seeds in colorectal cancer. PMID:29684110
Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs. PMID:29670884
Pan-cancer analysis of somatic mutations and transcriptomes reveals common functional gene clusters shared by multiple cancer types. PMID:29662161
Besides Pathology: Long Non-Coding RNA in Cell and Tissue Homeostasis. PMID:29657300
Rare Splice Variants in Long Non-Coding RNAs. PMID:29657294
Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis. PMID:29657277
Inference of the human polyadenylation code. PMID:29648582
PREDICTD PaRallel Epigenomics Data Imputation with Cloud-based Tensor Decomposition. PMID:29643364
Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia. PMID:29643186
Profiling expression of coding genes, long noncoding RNA, and circular RNA in lung adenocarcinoma by ribosomal RNA-depleted RNA sequencing. PMID:29632808
The Immune Landscape of Cancer. PMID:29628290
Recognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship. PMID:29626081
iCopyDAV: Integrated platform for copy number variations-Detection, annotation and visualization. PMID:29621297
iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation. PMID:29619235
Dynamic changes during the treatment of pancreatic cancer. PMID:29599906
Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing. PMID:29598823
QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data. PMID:29592814
Discovery of physiological and cancer-related regulators of 3' UTR processing with KAPAC. PMID:29592812
Single-Cell Digital Lysates Generated by Phase-Switch Microfluidic Device Reveal Transcriptome Perturbation of Cell Cycle. PMID:29589910
Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes. PMID:29563166
A comprehensive catalog of predicted functional upstream open reading frames in humans. PMID:29562350
De novo mutations in regulatory elements in neurodevelopmental disorders. PMID:29562236
Comparative transcriptome profiling of the human and mouse dorsal root ganglia: an RNA-seq-based resource for pain and sensory neuroscience research. PMID:29561359
The Ever-Evolving Concept of the Gene: The Use of RNA/Protein Experimental Techniques to Understand Genome Functions. PMID:29560353
Evaluation of two main RNA-seq approaches for gene quantification in clinical RNA sequencing: polyA+ selection versus rRNA depletion. PMID:29556074
Bivalent Chromatin Domains in Glioblastoma Reveal a Subtype-Specific Signature of Glioma Stem Cells. PMID:29549165
Long non-coding RNAs regulating macrophage functions in homeostasis and disease. PMID:29548902
Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci. PMID:29540241
Unveiling new interdependencies between significant DNA methylation sites, gene expression profiles and glioma patients survival. PMID:29535343
POLARIS: Polygenic LD-adjusted risk score approach for set-based analysis of GWAS data. PMID:29532500
Effects of Cadmium Exposure on DNA Methylation at Imprinting Control Regions and Genome-Wide in Mothers and Newborn Children. PMID:29529597
ChIP-ping the branches of the tree: functional genomics and the evolution of eukaryotic gene regulation. PMID:29529131
Global analysis of A-to-I RNA editing reveals association with common disease variants. PMID:29527417
The pseudogene-derived long non-coding RNA SFTA1P suppresses cell proliferation, migration, and invasion in gastric cancer. PMID:29523596
AltHapAlignR: improved accuracy of RNA-seq analyses through the use of alternative haplotypes. PMID:29514179
A large electronic-health-record-based genome-wide study of serum lipids. PMID:29507422
TERIUS: accurate prediction of lncRNA via high-throughput sequencing data representing RNA-binding protein association. PMID:29504902
Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. PMID:29500431
Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow. PMID:29500430
Identification of long noncoding RNAs involved in muscle differentiation. PMID:29499054
Data Mining of Small RNA-Seq Suggests an Association Between Prostate Cancer and Altered Abundance of 5' Transfer RNA Halves in Seminal Fluid and Prostatic Tissues. PMID:29497340
Novel and Haplotype Specific MicroRNAs Encoded by the Major Histocompatibility Complex. PMID:29497078
The Role of Long Non-Coding RNAs in Hepatocarcinogenesis. PMID:29495592
PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers. PMID:29491376
Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer. PMID:29463813
Dynamics of promoter bivalency and RNAP II pausing in mouse stem and differentiated cells. PMID:29458328
Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. PMID:29456158
Mutation in an alternative transcript of CDKL5 in a boy with early-onset seizures. PMID:29444904
A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. PMID:29441070
The effects of death and post-mortem cold ischemia on human tissue transcriptomes. PMID:29440659
Multi-Omics Driven Assembly and Annotation of the Sandalwood (Santalum album) Genome. PMID:29440596
An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells. PMID:29436261
Non-coding RNAs and retroviruses. PMID:29426337
A phenotype centric benchmark of variant prioritisation tools. PMID:29423277
Small non-coding RNA profiling in human biofluids and surrogate tissues from healthy individuals: description of the diverse and most represented species. PMID:29423032
Estimating the mutational load for cardiovascular diseases in Pakistani population. PMID:29420653
Enhancer redundancy provides phenotypic robustness in mammalian development. PMID:29420474
Region-Specific Methylation Profiling in Acute Myeloid Leukemia. PMID:29405013
Long non-coding and coding RNAs characterization in Peripheral Blood Mononuclear Cells and Spinal Cord from Amyotrophic Lateral Sclerosis patients. PMID:29402919
Crosstalk between long non-coding RNAs and Wnt/β-catenin signalling in cancer. PMID:29392884
Non-coding RNA dysregulation in the amygdala region of schizophrenia patients contributes to the pathogenesis of the disease. PMID:29391398
Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response. PMID:29386352
Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens. PMID:29386114
Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response. PMID:29379200
Mitotically-Associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer. PMID:29378907
Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies. PMID:29377896
Long non-coding RNA MDC1-AS inhibits human gastric cancer cell proliferation and metastasis through an MDC1-dependent mechanism. PMID:29375682
Evidence for a Pan-Neurodegenerative Disease Response in Huntington's and Parkinson's Disease Expression Profiles. PMID:29375298
Over-expression of oncigenic pesudogene DUXAP10 promotes cell proliferation and invasion by regulating LATS1 and β-catenin in gastric cancer. PMID:29374493
Functional Classification and Experimental Dissection of Long Noncoding RNAs. PMID:29373828
Biologically active constituents of the secretome of human W8B2+ cardiac stem cells. PMID:29371689
Expression profiling of snoRNAs in normal hematopoiesis and AML. PMID:29365324
Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World. PMID:29363314
Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast. PMID:29361568
CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion. PMID:29358169
Ultraconserved Enhancers Are Required for Normal Development. PMID:29358049
Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival. PMID:29354286
Integrative Genomic Analysis Predicts Causative Cis-Regulatory Mechanisms of the Breast Cancer-Associated Genetic Variant rs4415084. PMID:29351903
Elucidating distinct ion channel populations on the surface of hippocampal neurons via single-particle tracking recurrence analysis. PMID:29347346
Natural antisense transcripts in diseases: From modes of action to targeted therapies. PMID:29341438
Targeting IRF3 as a YAP agonist therapy against gastric cancer. PMID:29339449
LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations. PMID:29325141
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes. PMID:29311636
Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region. PMID:29311362
The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. PMID:29307494
HOTAIR Long Non-coding RNA: Characterizing the Locus Features by the In Silico Approaches. PMID:29307144
KIAA1109 Variants Are Associated with a Severe Disorder of Brain Development and Arthrogryposis. PMID:29290337
Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development. PMID:29290336
Principles and methods of in-silico prioritization of non-coding regulatory variants. PMID:29288389
Clinicopathological and Prognostic Role of Long Noncoding RNA Linc00152 in Various Human Neoplasms: Evidence from Meta-Analysis. PMID:29285514
Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers. PMID:29284524
DE-kupl: exhaustive capture of biological variation in RNA-seq data through k-mer decomposition. PMID:29284518
Intergenic disease-associated regions are abundant in novel transcripts. PMID:29284497
Detection of de novo single nucleotide variants in offspring of atomic-bomb survivors close to the hypocenter by whole-genome sequencing. PMID:29279608
The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer. PMID:29279323
Long Noncoding RNA in Cancer: Wiring Signaling Circuitry. PMID:29274663
An integrated and comparative approach towards identification, characterization and functional annotation of candidate genes for drought tolerance in sorghum (Sorghum bicolor (L.) Moench). PMID:29273003
RNA-Seq differential expression analysis: An extended review and a software tool. PMID:29267363
Genes uniquely expressed in human growth plate chondrocytes uncover a distinct regulatory network. PMID:29262782
Transcriptomic analysis of mitochondrial TFAM depletion changing cell morphology and proliferation. PMID:29259235
Resolving systematic errors in widely used enhancer activity assays in human cells. PMID:29256496
Beyond Transcription: Roles of Transcription Factors in Pre-mRNA Splicing. PMID:29251915
Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA. PMID:29245011
Collaborative representation-based classification of microarray gene expression data. PMID:29236759
Genomic and Epigenomic Signatures in Ovarian Cancer Associated with Resensitization to Platinum Drugs. PMID:29229600
Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort. PMID:29228364
RNAStructuromeDB: A genome-wide database for RNA structural inference. PMID:29222504
A comprehensive profile of circulating RNAs in human serum. PMID:29219730
Network analysis of pseudogene-gene relationships: from pseudogene evolution to their functional potentials. PMID:29218912
Light-focusing human micro-lenses generated from pluripotent stem cells model lens development and drug-induced cataract in vitro. PMID:29217756
Transcriptomic profiles in peripheral blood between women with unexplained recurrent implantation failure and recurrent miscarriage and the correlation with endometrium: A pilot study. PMID:29216287
LRSim: A Linked-Reads Simulator Generating Insights for Better Genome Partitioning. PMID:29213995
Ginkgo biloba extract EGb 761-induced upregulation of LincRNA-p21 inhibits colorectal cancer metastasis by associating with EZH2. PMID:29207671
Crosstalk in competing endogenous RNA network reveals the complex molecular mechanism underlying lung cancer. PMID:29207642
Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome. PMID:29196558
circlncRNAnet: an integrated web-based resource for mapping functional networks of long or circular forms of noncoding RNAs. PMID:29194536
A multiregional proteomic survey of the postnatal human brain. PMID:29184206
Transcriptome sequencing reveals high isoform diversity in the ant Formica exsecta. PMID:29177112
Rare copy number variants identified in prune belly syndrome. PMID:29174092
Molecular and cellular reorganization of neural circuits in the human lineage. PMID:29170230
Protein complex scaffolding predicted as a prevalent function of long non-coding RNAs. PMID:29165713
Partial bisulfite conversion for unique template sequencing. PMID:29161423
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data. PMID:29161273
Long non-coding RNAs in Colorectal Cancer: Progression and Future Directions. PMID:29158793
The discovery potential of RNA processing profiles. PMID:29155959
Ensembl 2018. PMID:29155950
Modeling positional effects of regulatory sequences with spline transformations increases prediction accuracy of deep neural networks. PMID:29155928
Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition. PMID:29150601
Human Accelerated Regions and Other Human-Specific Sequence Variations in the Context of Evolution and Their Relevance for Brain Development. PMID:29149249
Functional annotation of structural ncRNAs within enhancer RNAs in the human genome: implications for human disease. PMID:29138457
Long noncoding RNA XIST is a prognostic factor in colorectal cancer and inhibits 5-fluorouracil-induced cell cytotoxicity through promoting thymidylate synthase expression. PMID:29137332
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer. PMID:29136504
Deep RNA Sequencing Uncovers a Repertoire of Human Macrophage Long Intergenic Noncoding RNAs Modulated by Macrophage Activation and Associated With Cardiometabolic Diseases. PMID:29133519
Cis-SNPs Set Testing and PrediXcan Analysis for Gene Expression Data using Linear Mixed Models. PMID:29127305
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression. PMID:29127290
The Encyclopedia of DNA elements (ENCODE): data portal update. PMID:29126249
Consensus coding sequence (CCDS) database: a standardized set of human and mouse protein-coding regions supported by expert curation. PMID:29126148
MOAT: efficient detection of highly mutated regions with the Mutations Overburdening Annotations Tool. PMID:29121169
The effect of genetic variation on promoter usage and enhancer activity. PMID:29116076
Genome-wide association study identifies a novel locus for cannabis dependence. PMID:29112194
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. PMID:29109393
Reduced mutation rate in exons due to differential mismatch repair. PMID:29106418
High-throughput annotation of full-length long noncoding RNAs with capture long-read sequencing. PMID:29106417
Identification and Analysis of P53-Mediated Competing Endogenous RNA Network in Human Hepatocellular Carcinoma. PMID:29104512
A functional strategy to characterize expression Quantitative Trait Loci. PMID:29101457
A Long Noncoding RNA Signature That Predicts Pathological Complete Remission Rate Sensitively in Neoadjuvant Treatment of Breast Cancer. PMID:29096247
Two independent modes of chromatin organization revealed by cohesin removal. PMID:29094699
The ISB Cancer Genomics Cloud: A Flexible Cloud-Based Platform for Cancer Genomics Research. PMID:29092928
Transcription start site profiling of 15 anatomical regions of the Macaca mulatta central nervous system. PMID:29087374
Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis. PMID:29074988
Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq. PMID:29072160
Lnc2Meth: a manually curated database of regulatory relationships between long non-coding RNAs and DNA methylation associated with human disease. PMID:29069510
APPRIS 2017: principal isoforms for multiple gene sets. PMID:29069475
OverGeneDB: a database of 5' end protein coding overlapping genes in human and mouse genomes. PMID:29069459
Gene isoforms as expression-based biomarkers predictive of drug response in vitro. PMID:29066719
A heuristic model for computational prediction of human branch point sequence. PMID:29065858
Association analysis identifies 65 new breast cancer risk loci. PMID:29059683
dreamBase: DNA modification, RNA regulation and protein binding of expressed pseudogenes in human health and disease. PMID:29059382
CirGRDB: a database for the genome-wide deciphering circadian genes and regulators. PMID:29059379
Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues. PMID:29058714
Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos. PMID:29056335
LncRNAs: key players and novel insights into diabetes mellitus. PMID:29050364
A comprehensive genome-wide analysis of long noncoding RNA expression profile in hepatocellular carcinoma. PMID:29047230
RMBase v2.0: deciphering the map of RNA modifications from epitranscriptome sequencing data. PMID:29040692
Comprehensive analysis of circRNA expression profiles in humans by RAISE. PMID:29039477
A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome. PMID:29038160
cuRRBS: simple and robust evaluation of enzyme combinations for reduced representation approaches. PMID:29036576
PLncPRO for prediction of long non-coding RNAs (lncRNAs) in plants and its application for discovery of abiotic stress-responsive lncRNAs in rice and chickpea. PMID:29036354
Integrative Analysis of Transcription Factor Combinatorial Interactions Using a Bayesian Tensor Factorization Approach. PMID:29033978
Microarray Analysis Identifies the Potential Role of Long Non-Coding RNA in Regulating Neuroinflammation during Japanese Encephalitis Virus Infection. PMID:29033949
Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer's disease. PMID:29030541
Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons. PMID:29030469
Segway 2.0: Gaussian mixture models and minibatch training. PMID:29028889
Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens. PMID:29023490
The lncRNA TUG1 modulates proliferation in trophoblast cells via epigenetic suppression of RND3. PMID:29022920
Antigen receptor repertoire profiling from RNA-seq data. PMID:29020005
Data Resources for Human Functional Genomics. PMID:28989986
Exon Mapping in Long Noncoding RNAs Using Digital Filters. PMID:28989280
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome. PMID:28985510
Frequent miRNA-convergent fusion gene events in breast cancer. PMID:28983113
Genome-scale detection of positive selection in nine primates predicts human-virus evolutionary conflicts. PMID:28977405
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture. PMID:28973462
Accurate and reproducible functional maps in 127 human cell types via 2D genome segmentation. PMID:28973456
DART: a fast and accurate RNA-seq mapper with a partitioning strategy. PMID:28968831
The Immune Signaling Adaptor LAT Contributes to the Neuroanatomical Phenotype of 16p11.2 BP2-BP3 CNVs. PMID:28965845
Interaction between Social/Psychosocial Factors and Genetic Variants on Body Mass Index: A Gene-Environment Interaction Analysis in a Longitudinal Setting. PMID:28961216
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events. PMID:28959951
Human hepatic gene expression signature of non-alcoholic fatty liver disease progression, a meta-analysis. PMID:28955037
HLAProfiler utilizes k-mer profiles to improve HLA calling accuracy for rare and common alleles in RNA-seq data. PMID:28954626
Identification of hub genes involved in the development of hepatocellular carcinoma by transcriptome sequencing. PMID:28947976
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent. PMID:28941034
START: a system for flexible analysis of hundreds of genomic signal tracks in few lines of SQL-like queries. PMID:28938868
A novel lncRNA, LL22NC03-N64E9.1, represses KLF2 transcription through binding with EZH2 in colorectal cancer. PMID:28938648
A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis. PMID:28935693
CLIP-seq analysis of multi-mapped reads discovers novel functional RNA regulatory sites in the human transcriptome. PMID:28934506
5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers. PMID:28925386
The Function and Therapeutic Potential of Long Non-coding RNAs in Cardiovascular Development and Disease. PMID:28918050
Strategies for In Vivo Screening and Mitigation of Hepatotoxicity Associated with Antisense Drugs. PMID:28918038
An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure. PMID:28913923
Discriminating cirRNAs from other lncRNAs using a hierarchical extreme learning machine (H-ELM) algorithm with feature selection. PMID:28913654
Long non-coding RNA SeT and miR-155 regulate the Tnfα gene allelic expression profile. PMID:28910376
Acute doses of caffeine shift nervous system cell expression profiles toward promotion of neuronal projection growth. PMID:28904364
Catalog of Differentially Expressed Long Non-Coding RNA following Activation of Human and Mouse Innate Immune Response. PMID:28900427
Assessment of T-cell receptor repertoire and clonal expansion in peripheral T-cell lymphoma using RNA-seq data. PMID:28900149
LEF1-AS1, a long-noncoding RNA, promotes malignancy in glioblastoma. PMID:28894380
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer. PMID:28891793
Identification of high-confidence RNA regulatory elements by combinatorial classification of RNA-protein binding sites. PMID:28886744
Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension. PMID:28881789
Up-regulation of long non-coding RNA SPRY4-IT1 promotes tumor cell migration and invasion in lung adenocarcinoma. PMID:28881629
LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression. PMID:28880276
An in-silico approach to predict and exploit synthetic lethality in cancer metabolism. PMID:28878380
Non-parametric genetic prediction of complex traits with latent Dirichlet process regression models. PMID:28878256
APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism. PMID:28878238
Atropos: specific, sensitive, and speedy trimming of sequencing reads. PMID:28875074
The Schistosoma mansoni genome encodes thousands of long non-coding RNAs predicted to be functional at different parasite life-cycle stages. PMID:28874839
Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer. PMID:28874753
Biology and clinical relevance of noncoding sno/scaRNAs. PMID:28869095
Spatial Clustering of de Novo Missense Mutations Identifies Candidate Neurodevelopmental Disorder-Associated Genes. PMID:28867141
Genome-wide computational analysis of potential long noncoding RNA mediated DNA:DNA:RNA triplexes in the human genome. PMID:28865451
Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL. PMID:28863214
Identification of dysregulated lncRNAs profiling and metastasis-associated lncRNAs in colorectal cancer by genome-wide analysis. PMID:28857495
Noncoding RNAs in neurodegeneration. PMID:28855739
RNA-seq reveals more consistent reference genes for gene expression studies in human non-melanoma skin cancers. PMID:28852586
FANTOM5 CAGE profiles of human and mouse reprocessed for GRCh38 and GRCm38 genome assemblies. PMID:28850105
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities. PMID:28847005
Two modes of targeting transposable elements by piRNA pathway in human testis. PMID:28842508
Integrated analysis of long non-coding RNAs in human gastric cancer: An in silico study. PMID:28841672
Characterization of lincRNA expression in the human retinal pigment epithelium and differentiated induced pluripotent stem cells. PMID:28837677
An integrated expression atlas of miRNAs and their promoters in human and mouse. PMID:28829439
Transcriptome analysis reveals long intergenic non-coding RNAs involved in skeletal muscle growth and development in pig. PMID:28821716
Aggregation of population-based genetic variation over protein domain homologues and its potential use in genetic diagnostics. PMID:28815929
Understanding the Role of lncRNAs in Nervous System Development. PMID:28815543
Omni-PolyA: a method and tool for accurate recognition of Poly(A) signals in human genomic DNA. PMID:28810905
Discovery of Variants Underlying Host Susceptibility to Virus Infection Using Whole-Exome Sequencing. PMID:28808973
Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment. PMID:28808237
Identification and characterization of a long non-coding RNA up-regulated during HIV-1 infection. PMID:28803142
Molecular pathogenesis of human prostate basal cell hyperplasia. PMID:28795417
The non-coding RNA landscape of human hematopoiesis and leukemia. PMID:28794406
Downregulation of lncRNA SDPR-AS is associated with poor prognosis in renal cell carcinoma. PMID:28790838
Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena. PMID:28789687
Evaluation and comparison of computational tools for RNA-seq isoform quantification. PMID:28784092
SuperTranscripts: a data driven reference for analysis and visualisation of transcriptomes. PMID:28778180
Integrative whole-genome sequence analysis reveals roles of regulatory mutations in BCL6 and BCL2 in follicular lymphoma. PMID:28765546
Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis. PMID:28757239
High resolution temporal transcriptomics of mouse embryoid body development reveals complex expression dynamics of coding and noncoding loci. PMID:28751729
Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network. PMID:28750683
Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits. PMID:28746338
Identification of four prognostic LncRNAs for survival prediction of patients with hepatocellular carcinoma. PMID:28729955
Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity. PMID:28724976
Bioinformatics analysis to identify the critical genes, microRNAs and long noncoding RNAs in melanoma. PMID:28723760
microRNA dependent and independent deregulation of long non-coding RNAs by an oncogenic herpesvirus. PMID:28715488
Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment. PMID:28695822
Strength of functional signature correlates with effect size in autism. PMID:28687074
Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis. PMID:28680106
Landscape and variation of novel retroduplications in 26 human populations. PMID:28662076
Korean Variant Archive (KOVA): a reference database of genetic variations in the Korean population. PMID:28655895
Metabolic autopsy with next generation sequencing in sudden unexpected death in infancy: Postmortem diagnosis of fatty acid oxidation disorders. PMID:28649538
A genome-wide association scan of biological processes involved in oral lichen planus and oral squamous cell carcinoma. PMID:28640079
Long Noncoding RNAs as Biomarkers in Cancer. PMID:28634418
The islet-resident macrophage is in an inflammatory state and senses microbial products in blood. PMID:28630088
Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription. PMID:28628087
Insights from Global Analyses of Long Noncoding RNAs in Breast Cancer. PMID:28616363
Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls. PMID:28606096
Genetic diagnosis of Mendelian disorders via RNA sequencing. PMID:28604674
Computational prediction of lncRNA-mRNA interactionsby integrating tissue specificity in human transcriptome. PMID:28595592
A DNA methylation map of human cancer at single base-pair resolution. PMID:28581523
Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells. PMID:28579393
Research focused on microRNAs: a link between myocardial remodeling and growth during pathological processes and physical exercises. PMID:28567402
Genome annotation for clinical genomic diagnostics: strengths and weaknesses. PMID:28558813
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. PMID:28552616
Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9. PMID:28550296
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations. PMID:28548104
Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits. PMID:28548082
The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. PMID:28546511
Copy-number variants and candidate gene mutations in isolated split hand/foot malformation. PMID:28539665
Identification and Characterization of a Class of MALAT1-like Genomic Loci. PMID:28538188
A computationally constructed ceRNA interaction network based on a comparison of the SHEE and SHEEC cell lines. PMID:28536623
Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia. PMID:28533390
Coordinates and intervals in graph-based reference genomes. PMID:28521770
Functionally diverse human T cells recognize non-microbial antigens presented by MR1. PMID:28518056
Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer. PMID:28504305
Prediction of gene expression with cis-SNPs using mixed models and regularization methods. PMID:28490319
Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature. PMID:28489852
Common genetic variation drives molecular heterogeneity in human iPSCs. PMID:28489815
Selective expression of long non-coding RNAs in a breast cancer cell progression model. PMID:28488769
The identification and functional annotation of RNA structures conserved in vertebrates. PMID:28487280
Soft Sweeps Are the Dominant Mode of Adaptation in the Human Genome. PMID:28482049
Comparative transcriptomics in human and mouse. PMID:28479595
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. PMID:28474669
Mapping the human DC lineage through the integration of high-dimensional techniques. PMID:28473638
Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia. PMID:28473620
Exploring genetic associations with ceRNA regulation in the human genome. PMID:28472449
RegulatorTrail: a web service for the identification of key transcriptional regulators. PMID:28472408
Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche. PMID:28462379
RIblast: an ultrafast RNA-RNA interaction prediction system based on a seed-and-extension approach. PMID:28459942
A comprehensive analysis of cancer-driving mutations and genes in kidney cancer. PMID:28454375
Accumulation of GAS5 in exosomes is a marker of apoptosis induction. PMID:28451400
Orphan CpG islands define a novel class of highly active enhancers. PMID:28448736
A three-lncRNA expression signature associated with the prognosis of gastric cancer patients. PMID:28444881
Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer. PMID:28441948
Normalized long read RNA sequencing in chicken reveals transcriptome complexity similar to human. PMID:28438136
Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. PMID:28430919
Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. PMID:28426890
Novel lincRNA SLINKY is a prognostic biomarker in kidney cancer. PMID:28423633
Genetic sequence-based prediction of long-range chromatin interactions suggests a potential role of short tandem repeat sequences in genome organization. PMID:28420341
Exploring the molecular pathogenesis and biomarkers of high risk oral premalignant lesions on the basis of long noncoding RNA expression profiling by serial analysis of gene expression. PMID:28418939
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition. PMID:28407681
SnoVault and encodeD: A novel object-based storage system and applications to ENCODE metadata. PMID:28403240
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly. PMID:28396521
High-confidence coding and noncoding transcriptome maps. PMID:28396519
Exploring functions of long noncoding RNAs across multiple cancers through co-expression network. PMID:28389669
De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14+ monocytes and in adipose tissue. PMID:28389524
Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells. PMID:28388430
Aberrant DNA Methylation in Human iPSCs Associates with MYC-Binding Motifs in a Clone-Specific Manner Independent of Genetics. PMID:28388429
LncATLAS database for subcellular localization of long noncoding RNAs. PMID:28386015
Nicotinic alpha 7 receptor expression and modulation of the lung epithelial response to lipopolysaccharide. PMID:28384302
Brain Transcriptome Sequencing of a Natural Model of Alzheimer's Disease. PMID:28373841
Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. PMID:28369036
Exploiting Long Noncoding RNAs as Pharmacological Targets to Modulate Epigenetic Diseases. PMID:28356895
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. PMID:28351387
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection. PMID:28346446
DeepBlueR: large-scale epigenomic analysis in R. PMID:28334349
QRank: a novel quantile regression tool for eQTL discovery. PMID:28334222
Network perturbation by recurrent regulatory variants in cancer. PMID:28333928
CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells. PMID:28321286
Time-dependent genetic effects on gene expression implicate aging processes. PMID:28302734
The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not C10orf55, selectively increasing production of normal PLAU transcripts by megakaryocytes but not granulocytes. PMID:28301587
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors that Can Function as a Cell of Origin for Prostate Cancer. PMID:28297567
Comprehensive RNA-seq transcriptomic profiling in the malignant progression of gliomas. PMID:28291232
Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data. PMID:28288115
The birth of a human-specific neural gene by incomplete duplication and gene fusion. PMID:28279197
TT-seq captures enhancer landscapes immediately after T-cell stimulation. PMID:28270558
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites. PMID:28263315
GuideScan software for improved single and paired CRISPR guide RNA design. PMID:28263296
Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome. PMID:28260531
Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion. PMID:28253259
Uncovering the roles of long non-coding RNAs in cancer stem cells. PMID:28245841
An atlas of human long non-coding RNAs with accurate 5' ends. PMID:28241135
Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression. PMID:28235201
Evolution of Brain Active Gene Promoters in Human Lineage Towards the Increased Plasticity of Gene Regulation. PMID:28233272
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor. PMID:28232751
Comparative genomic analysis of eutherian kallikrein genes. PMID:28224083
Distal CpG islands can serve as alternative promoters to transcribe genes with silenced proximal promoters. PMID:28223400
Manananggal - a novel viewer for alternative splicing events. PMID:28222683
Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects. PMID:28216383
Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer. PMID:28214253
Epigenetic Landscape during Coronavirus Infection. PMID:28212305
Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer. PMID:28209205
Recurrently deregulated lncRNAs in hepatocellular carcinoma. PMID:28194035
Improved regulatory element prediction based on tissue-specific local epigenomic signatures. PMID:28193886
Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. PMID:28193769
Large-scale bioactivity analysis of the small-molecule assayed proteome. PMID:28178331
Dnmt3a restrains mast cell inflammatory responses. PMID:28167789
LocExpress: a web server for efficiently estimating expression of novel transcripts. PMID:28155723
DeepGene: an advanced cancer type classifier based on deep learning and somatic point mutations. PMID:28155641
Long noncoding RNA expression signature to predict platinum-based chemotherapeutic sensitivity of ovarian cancer patients. PMID:28154416
Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom. PMID:28145424
Discovery of Cancer Driver Long Noncoding RNAs across 1112 Tumour Genomes: New Candidates and Distinguishing Features. PMID:28128360
Correlated 5-Hydroxymethylcytosine (5hmC) and Gene Expression Profiles Underpin Gene and Organ-Specific Epigenetic Regulation in Adult Mouse Brain and Liver. PMID:28125731
Immunobiology of Long Noncoding RNAs. PMID:28125358
Lncident: A Tool for Rapid Identification of Long Noncoding RNAs Utilizing Sequence Intrinsic Composition and Open Reading Frame Information. PMID:28116287
Robust and rapid algorithms facilitate large-scale whole genome sequencing downstream analysis in an integrative framework. PMID:28115622
The Long Noncoding RNA Landscape of the Ischemic Human Left Ventricle. PMID:28115490
Tethered Oligonucleotide-Primed Sequencing, TOP-Seq: A High-Resolution Economical Approach for DNA Epigenome Profiling. PMID:28111014
Antisense transcription of the myotonic dystrophy locus yields low-abundant RNAs with and without (CAG)n repeat. PMID:28102759
Mitochondrial respiratory gene expression is suppressed in many cancers. PMID:28099114
Identification of Potential Key lncRNAs and Genes Associated with Aging Based on Microarray Data of Adipocytes from Mice. PMID:28097151
Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia. PMID:28096303
Massive Effect on LncRNAs in Human Monocytes During Fungal and Bacterial Infections and in Response to Vitamins A and D. PMID:28094339
Insertions and Deletions Target Lineage-Defining Genes in Human Cancers. PMID:28089356
RAIN: RNA-protein Association and Interaction Networks. PMID:28077569
Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer. PMID:28077088
Long noncoding RNA repertoire in chicken liver and adipose tissue. PMID:28073357
A potential prognostic lncRNA signature for predicting survival in patients with bladder urothelial carcinoma. PMID:28060759
Genome-Wide DNA Methylation Patterns Analysis of Noncoding RNAs in Temporal Lobe Epilepsy Patients. PMID:28058582
The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states. PMID:28054653
POSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins. PMID:28053162
FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome. PMID:28053114
Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status. PMID:28053090
ChimPipe: accurate detection of fusion genes and transcription-induced chimeras from RNA-seq data. PMID:28049418
Long Noncoding RNA Identification: Comparing Machine Learning Based Tools for Long Noncoding Transcripts Discrimination. PMID:28042575
Human splicing diversity and the extent of unannotated splice junctions across human RNA-seq samples on the Sequence Read Archive. PMID:28038678
Involvement of Host Non-Coding RNAs in the Pathogenesis of the Influenza Virus. PMID:28035991
Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools. PMID:28035947
Integration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci. PMID:28035019
Androgen-induced lncRNA POTEF-AS1 regulates apoptosis-related pathway to facilitate cell survival in prostate cancer cells. PMID:28032932
Targeted Sequencing of FKBP5 in Suicide Attempters with Bipolar Disorder. PMID:28030643
Down syndrome and the complexity of genome dosage imbalance. PMID:28029161
GeneBase 1.1: a tool to summarize data from NCBI gene datasets and its application to an update of human gene statistics. PMID:28025344
Genome-wide mapping of autonomous promoter activity in human cells. PMID:28024146
High-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE. PMID:28011790
Role of lncRNAs in Cellular Aging. PMID:27999563
Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury. PMID:27994070
Using reference-free compressed data structures to analyze sequencing reads from thousands of human genomes. PMID:27986821
A cloud-based workflow to quantify transcript-expression levels in public cancer compendia. PMID:27982081
Integrating Epigenomics into the Understanding of Biomedical Insight. PMID:27980397
Large-scale mapping of mammalian transcriptomes identifies conserved genes associated with different cell states. PMID:27980097
Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells. PMID:27965357
Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts. PMID:27956497
A GC-rich sequence feature in the 3' UTR directs UPF1-dependent mRNA decay in mammalian cells. PMID:27940950
Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs. PMID:27927715
ChIPBase v2.0: decoding transcriptional regulatory networks of non-coding RNAs and protein-coding genes from ChIP-seq data. PMID:27924033
Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line. PMID:27917920
Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis. PMID:27916529
Differential variation patterns between hubs and bottlenecks in human protein-protein interaction networks. PMID:27903259
Identification of laryngeal cancer prognostic biomarkers using an inflammatory gene-related, competitive endogenous RNA network. PMID:27902487
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). PMID:27899670
The BIG Data Center: from deposition to integration to translation. PMID:27899658
The UCSC Genome Browser database: 2017 update. PMID:27899642
Ensembl 2017. PMID:27899575
Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model. PMID:27898737
Prioritization of non-coding disease-causing variants and long non-coding RNAs in liver cancer. PMID:27895760
Discovery and genotyping of structural variation from long-read haploid genome sequence data. PMID:27895111
Simulating Next-Generation Sequencing Datasets from Empirical Mutation and Sequencing Models. PMID:27893777
SPECtre: a spectral coherence--based classifier of actively translated transcripts from ribosome profiling sequence data. PMID:27884106
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences. PMID:27881428
Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer. PMID:27876760
Integrative classification of human coding and noncoding genes through RNA metabolism profiles. PMID:27870833
TACO produces robust multisample transcriptome assemblies from RNA-seq. PMID:27869815
The BLUEPRINT Data Analysis Portal. PMID:27863955
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. PMID:27863251
An imprinted long noncoding RNA located between genes Meg8 and Meg9 in the cattle Dlk1-Dio3 domain. PMID:27858207
Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers. PMID:27856756
Size distribution of function-based human gene sets and the split-merge model. PMID:27853602
Multiparameter functional diversity of human C2H2 zinc finger proteins. PMID:27852650
AnnoLnc: a web server for systematically annotating novel human lncRNAs. PMID:27852242
Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion. PMID:27846841
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. PMID:27841878
Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues. PMID:27835642
Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits. PMID:27833659
The prognostic value of long non coding RNAs in non small cell lung cancer: A meta-analysis. PMID:27833074
A Comprehensive Characterization of the Function of LincRNAs in Transcriptional Regulation Through Long-Range Chromatin Interactions. PMID:27824113
Transcriptome analysis of distinct long non-coding RNA transcriptional fingerprints in lung adenocarcinoma and squamous cell carcinoma. PMID:27797003
Natural Selection in the Great Apes. PMID:27795229
Long non-coding RNA FOXP4-AS1 is an unfavourable prognostic factor and regulates proliferation and apoptosis in colorectal cancer. PMID:27790757
KERIS: kaleidoscope of gene responses to inflammation between species. PMID:27789704
Genetic Variants in Isolated Ebstein Anomaly Implicated in Myocardial Development Pathways. PMID:27788187
Flexible Data Analysis Pipeline for High-Confidence Proteogenomics. PMID:27786492
Transcriptome-wide effects of inverted SINEs on gene expression and their impact on RNA polymerase II activity. PMID:27782844
Divergent lncRNAs take the lead on pluripotent cell differentiation. PMID:27777936
The state of play in higher eukaryote gene annotation. PMID:27773922
Integrated Post-GWAS Analysis Sheds New Light on the Disease Mechanisms of Schizophrenia. PMID:27754856
The human-induced pluripotent stem cell initiative-data resources for cellular genetics. PMID:27733501
Novel microRNA discovery using small RNA sequencing in post-mortem human brain. PMID:27716130
Specific genomic cues regulate Cajal body assembly. PMID:27715441
Alternative Splicing May Not Be the Key to Proteome Complexity. PMID:27712956
lncScore: alignment-free identification of long noncoding RNA from assembled novel transcripts. PMID:27708423
De novo assembly and phasing of a Korean human genome. PMID:27706134
Genome-wide compendium and functional assessment of in vivo heart enhancers. PMID:27703156
Consensus Analysis of Whole Transcriptome Profiles from Two Breast Cancer Patient Cohorts Reveals Long Non-Coding RNAs Associated with Intrinsic Subtype and the Tumour Microenvironment. PMID:27685983
Long noncoding RNA (lincRNA), a new paradigm in gene expression control. PMID:27681237
Genome-wide associations for birth weight and correlations with adult disease. PMID:27680694
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor. PMID:27671624
Analysis of SOX2-Regulated Transcriptome in Glioma Stem Cells. PMID:27669421
Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators. PMID:27667668
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants. PMID:27666373
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing. PMID:27662090
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. PMID:27661255
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. PMID:27647875
CardioTF, a database of deconstructing transcriptional circuits in the heart system. PMID:27635320
Genome-wide identification and characterisation of HOT regions in the human genome. PMID:27633377
The Tetraodon nigroviridis reference transcriptome: developmental transition, length retention and microsynteny of long non-coding RNAs in a compact vertebrate genome. PMID:27628538
Maps of context-dependent putative regulatory regions and genomic signal interactions. PMID:27625394
BmncRNAdb: a comprehensive database of non-coding RNAs in the silkworm, Bombyx mori. PMID:27623959
Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing. PMID:27617755
Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes. PMID:27613107
COME: a robust coding potential calculation tool for lncRNA identification and characterization based on multiple features. PMID:27608726
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome. PMID:27571552
Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control. PMID:27568222
Single-nucleus RNA-seq of differentiating human myoblasts reveals the extent of fate heterogeneity. PMID:27566152
Investigation of novel LPS-induced differentially expressed long non-coding RNAs in endothelial cells. PMID:27565812
Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. PMID:27559081
An integrative transcriptomic atlas of organogenesis in human embryos. PMID:27557446
A molecular conundrum involving hypothalamic responses to and roles of long non-coding RNAs following food deprivation. PMID:27555291
Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults. PMID:27546487
lncRNA expression in the auditory forebrain during postnatal development. PMID:27544636
Identification and functional analysis of long non-coding RNAs in human and mouse early embryos based on single-cell transcriptome data. PMID:27542205
Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases. PMID:27540175
Mouse models of Down syndrome: gene content and consequences. PMID:27538963
Extension of human lncRNA transcripts by RACE coupled with long-read high-throughput sequencing (RACE-Seq). PMID:27531712
reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4(+) memory T cells. PMID:27530917
Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer. PMID:27526323
NOTCH1 mediates a switch between two distinct secretomes during senescence. PMID:27525720
IRWRLDA: improved random walk with restart for lncRNA-disease association prediction. PMID:27517318
Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers. PMID:27513638
IPMiner: hidden ncRNA-protein interaction sequential pattern mining with stacked autoencoder for accurate computational prediction. PMID:27506469
Simultaneous detection and estimation of trait associations with genomic phenotypes. PMID:27496912
Comparative Transcriptome Analysis Reveals Substantial Tissue Specificity in Human Aortic Valve. PMID:27493474
Statistical Methods in Integrative Genomics. PMID:27482531
Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions. PMID:27482468
A targeted sequencing study of glutamatergic candidate genes in suicide attempters with bipolar disorder. PMID:27480506
Investigating long noncoding RNAs using animal models. PMID:27479747
A Long Noncoding RNA Regulates Sister Chromatid Cohesion. PMID:27477908
FocalScan: Scanning for altered genes in cancer based on coordinated DNA and RNA change. PMID:27474725
Secondary structure impacts patterns of selection in human lncRNAs. PMID:27457204
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters. PMID:27455346
Immune DNA signature of T-cell infiltration in breast tumor exomes. PMID:27452728
TALE-directed local modulation of H3K9 methylation shapes exon recognition. PMID:27439481
Expression of evolutionarily novel genes in tumors. PMID:27437030
PETModule: a motif module based approach for enhancer target gene prediction. PMID:27436110
Identification and Classification of New Transcripts in Dorper and Small-Tailed Han Sheep Skeletal Muscle Transcriptomes. PMID:27434270
Long noncoding RNAs and Alzheimer's disease. PMID:27418812
Integrative analysis with ChIP-seq advances the limits of transcript quantification from RNA-seq. PMID:27405803
The genetic architecture of type 2 diabetes. PMID:27398621
Limits of Peripheral Blood Mononuclear Cells for Gene Expression-Based Biomarkers in Juvenile Idiopathic Arthritis. PMID:27385437
A comprehensive analysis of 3' end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation. PMID:27382025
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. PMID:27378374
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. PMID:27376578
Identifying Centromeric RNAs Involved in Histone Dynamics In Vivo. PMID:27372766
Circulating biomarkers to monitor cancer progression and treatment. PMID:27358717
The genetic regulatory signature of type 2 diabetes in human skeletal muscle. PMID:27353450
Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression. PMID:27353328
JAK-STAT signaling in cancer: From cytokines to non-coding genome. PMID:27349799
Overexpression of long non-coding RNA HOTTIP increases chemoresistance of osteosarcoma cell by activating the Wnt/β-catenin pathway. PMID:27347346
Functional annotation of noncoding variants and prioritization of cancer-associated lncRNAs in lung cancer. PMID:27347129
Long non-coding RNAs and complex diseases: from experimental results to computational models. PMID:27345524
Androgen-induced Long Noncoding RNA (lncRNA) SOCS2-AS1 Promotes Cell Growth and Inhibits Apoptosis in Prostate Cancer Cells. PMID:27342777
The Ensembl gene annotation system. PMID:27337980
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq. PMID:27329541
PEDLA: predicting enhancers with a deep learning-based algorithmic framework. PMID:27329130
IntNetLncSim: an integrative network analysis method to infer human lncRNA functional similarity. PMID:27323856
FMLNCSIM: fuzzy measure-based lncRNA functional similarity calculation model. PMID:27322210
Long noncoding RNA variations in cardiometabolic diseases. PMID:27305986
Boiler: lossy compression of RNA-seq alignments using coverage vectors. PMID:27298258
Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research. PMID:27297499
Long noncoding RNAs: Central to nervous system development. PMID:27296516
Emergence and Evolution of Hominidae-Specific Coding and Noncoding Genomic Sequences. PMID:27289096
Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe. PMID:27287230
Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication. PMID:27283940
Global transcriptome analysis for identification of interactions between coding and noncoding RNAs during human erythroid differentiation. PMID:27272188
The Ensembl Variant Effect Predictor. PMID:27268795
Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow. PMID:27250503
Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model. PMID:27246810
A penalized likelihood approach for robust estimation of isoform expression. PMID:27239250
An atlas of gene expression and gene co-regulation in the human retina. PMID:27235414
Long noncoding RNAs in cancer: mechanisms of action and technological advancements. PMID:27233618
Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling. PMID:27232982
Group II mGluRs suppress hyperexcitability in mouse and human nociceptors. PMID:27218869
Prediction and Quantification of Splice Events from RNA-Seq Data. PMID:27218464
Improved definition of the mouse transcriptome via targeted RNA sequencing. PMID:27197243
Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks. PMID:27197224
Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. PMID:27195672
Circulating long non-coding RNAs in cancer: current status and future perspectives. PMID:27189224
Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. PMID:27162171
Dissecting the expression relationships between RNA-binding proteins and their cognate targets in eukaryotic post-transcriptional regulatory networks. PMID:27161996
RNAex: an RNA secondary structure prediction server enhanced by high-throughput structure-probing data. PMID:27137891
IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity. PMID:27111142
A benchmark for RNA-seq quantification pipelines. PMID:27107712
Jointly characterizing epigenetic dynamics across multiple human cell types. PMID:27095202
Candidate SNP Markers of Gender-Biased Autoimmune Complications of Monogenic Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters. PMID:27092142
A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals. PMID:27089393
Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis. PMID:27088242
Allele-Skewed DNA Modification in the Brain: Relevance to a Schizophrenia GWAS. PMID:27087318
Nucleotide excision repair is impaired by binding of transcription factors to DNA. PMID:27075101
Comprehensive analysis of lncRNA expression profiles reveals a novel lncRNA signature to discriminate nonequivalent outcomes in patients with ovarian cancer. PMID:27074572
Long Noncoding RNAs in Cancer Pathways. PMID:27070700
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. PMID:27064257
Enhancer-promoter interactions are encoded by complex genomic signatures on looping chromatin. PMID:27064255
Diagnostic and Biological Significance of KIR Expression Profile Determined by RNA-Seq in Natural Killer/T-Cell Lymphoma. PMID:27060228
Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation. PMID:27049631
Long non-coding RNA Databases in Cardiovascular Research. PMID:27049585
Transcriptomics resources of human tissues and organs. PMID:27044256
Long-read sequence assembly of the gorilla genome. PMID:27034376
Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs. PMID:27034163
Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome. PMID:27030248
Transcript Isoform Variation Associated with Cytosine Modification in Human Lymphoblastoid Cell Lines. PMID:27029734
ILNCSIM: improved lncRNA functional similarity calculation model. PMID:27028993
Long Intergenic Noncoding RNAs Mediate the Human Chondrocyte Inflammatory Response and Are Differentially Expressed in Osteoarthritis Cartilage. PMID:27023358
Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease. PMID:27021820
Transcriptomic and epigenomic characterization of the developing bat wing. PMID:27019111
Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts. PMID:27009863
Mechanisms of long noncoding RNA function in development and disease. PMID:27007508
CTCF-mediated chromatin loops enclose inducible gene regulatory domains. PMID:27004515
dbWGFP: a database and web server of human whole-genome single nucleotide variants and their functional predictions. PMID:26989155
Human Knockout Carriers: Dead, Diseased, Healthy, or Improved? PMID:26988438
CLASS2: accurate and efficient splice variant annotation from RNA-seq reads. PMID:26975657
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. PMID:26974950
RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation. PMID:26974154
Constructing 3D interaction maps from 1D epigenomes. PMID:26960733
Gene expression variability in mammalian embryonic stem cells using single cell RNA-seq data. PMID:26951854
Identification and characterization of lncRNA mediated transcriptional dysregulation dictates lncRNA roles in glioblastoma. PMID:26943771
Identification of STOML2 as a putative novel asthma risk gene associated with IL6R. PMID:26932604
A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes. PMID:26931494
Pseudo-Reference-Based Assembly of Vertebrate Transcriptomes. PMID:26927182
Changes in snoRNA and snRNA Abundance in the Human, Chimpanzee, Macaque, and Mouse Brain. PMID:26926764
An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer. PMID:26921330
Systematic characterization of lncRNAs' cell-to-cell expression heterogeneity in glioblastoma cells. PMID:26918340
Transcriptome Analysis in Domesticated Species: Challenges and Strategies. PMID:26917953
The Role of Long Noncoding RNAs in Neurodegenerative Diseases. PMID:26910817
Genetic mutations associated with metastatic clear cell renal cell carcinoma. PMID:26908440
A Long Non-coding RNA, lncLGR, Regulates Hepatic Glucokinase Expression and Glycogen Storage during Fasting. PMID:26904944
Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs. PMID:26898941
Probabilistic Modeling of Imaging, Genetics and Diagnosis. PMID:26886973
Widespread RNA binding by chromatin-associated proteins. PMID:26883116
IGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicity. PMID:26880249
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading. PMID:26878238
Single-cell Transcriptome Study as Big Data. PMID:26876720
SplAdder: identification, quantification and testing of alternative splicing events from RNA-Seq data. PMID:26873928
CCSI: a database providing chromatin-chromatin spatial interaction information. PMID:26868054
Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer. PMID:26868017
Filtering genetic variants and placing informative priors based on putative biological function. PMID:26866982
Mutation pattern is an influential factor on functional mutation rates in cancer. PMID:26865835
Curated eutherian third party data gene data sets. PMID:26862561
Genome-wide identification and characterization of long intergenic noncoding RNAs and their potential association with larval development in the Pacific oyster. PMID:26861843
Biochemical Methods To Investigate lncRNA and the Influence of lncRNA:Protein Complexes on Chromatin. PMID:26859437
ePIANNO: ePIgenomics ANNOtation tool. PMID:26859295
Redifferentiation of expanded human islet β cells by inhibition of ARX. PMID:26856418
Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines. PMID:26856248
Long non-coding RNA LINC01133 represses KLF2, P21 and E-cadherin transcription through binding with EZH2, LSD1 in non small cell lung cancer. PMID:26840083
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs. PMID:26838501
Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans. PMID:26821746
Comprehensive prediction of lncRNA-RNA interactions in human transcriptome. PMID:26818453
Identifying micro-inversions using high-throughput sequencing reads. PMID:26818118
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer. PMID:26813288
Noncoding RNAs and pancreatic cancer. PMID:26811626
Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes. PMID:26783963
RNAseq analysis for the diagnosis of muscular dystrophy. PMID:26783550
cnvScan: a CNV screening and annotation tool to improve the clinical utility of computational CNV prediction from exome sequencing data. PMID:26764020
Identifying and functionally characterizing tissue-specific and ubiquitously expressed human lncRNAs. PMID:26760768
QuickRNASeq lifts large-scale RNA-seq data analyses to the next level of automation and interactive visualization. PMID:26747388
A proteogenomic approach to understand splice isoform functions through sequence and expression-based computational modeling. PMID:26740460
ELF5 isoform expression is tissue-specific and significantly altered in cancer. PMID:26738740
Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames. PMID:26728094
In Silico Functional Annotation of Genomic Variation. PMID:26724722
Derivation of consensus inactivation status for X-linked genes from genome-wide studies. PMID:26719789
Identification of important long non-coding RNAs and highly recurrent aberrant alternative splicing events in hepatocellular carcinoma through integrative analysis of multiple RNA-Seq datasets. PMID:26711644
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. PMID:26701265
Non-coding yet non-trivial: a review on the computational genomics of lincRNAs. PMID:26697116
Forward Individualized Medicine from Personal Genomes to Interactomes. PMID:26696898
Obesity-related known and candidate SNP markers can significantly change affinity of TATA-binding protein for human gene promoters. PMID:26694100
Long noncoding RNAs in cancer: from function to translation. PMID:26693181
Decreased long noncoding RNA MIR31HG is correlated with poor prognosis and contributes to cell proliferation in gastric cancer. PMID:26692098
Stress and glucocorticoid receptor transcriptional programming in time and space: Implications for the brain-gut axis. PMID:26690871
Ensembl 2016. PMID:26687719
Many lncRNAs, 5'UTRs, and pseudogenes are translated and some are likely to express functional proteins. PMID:26687005
Comprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination. PMID:26683846
A human haploid gene trap collection to study lncRNAs with unusual RNA biology. PMID:26670263
Unique features of long non-coding RNA biogenesis and function. PMID:26666209
Rare copy number variants implicated in posterior urethral valves. PMID:26663319
Detecting actively translated open reading frames in ribosome profiling data. PMID:26657557
proBAMsuite, a Bioinformatics Framework for Genome-Based Representation and Analysis of Proteomics Data. PMID:26657539
The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAs. PMID:26654912
Comparative genomic analysis of eutherian tumor necrosis factor ligand genes. PMID:26646413
Integrating Diverse Types of Genomic Data to Identify Genes that Underlie Adverse Pregnancy Phenotypes. PMID:26641094
RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. PMID:26636579
The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease. PMID:26636336
LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes. PMID:26633036
ADMIRE: analysis and visualization of differential methylation in genomic regions using the Infinium HumanMethylation450 Assay. PMID:26628921
Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors. PMID:26624892
Variable reproducibility in genome-scale public data: A case study using ENCODE ChIP sequencing resource. PMID:26619763
Towards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond. PMID:26615025
DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts. PMID:26612864
Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells. PMID:26602695
RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles. PMID:26597164
The UCSC Genome Browser database: 2016 update. PMID:26590259
deepBase v2.0: identification, expression, evolution and function of small RNAs, LncRNAs and circular RNAs from deep-sequencing data. PMID:26590255
Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain. PMID:26590212
Identification of global regulators of T-helper cell lineage specification. PMID:26589177
A Dual Model for Prioritizing Cancer Mutations in the Non-coding Genome Based on Germline and Somatic Events. PMID:26588488
CpG island erosion, polycomb occupancy and sequence motif enrichment at bivalent promoters in mammalian embryonic stem cells. PMID:26582124
Death of a dogma: eukaryotic mRNAs can code for more than one protein. PMID:26578573
KATZLDA: KATZ measure for the lncRNA-disease association prediction. PMID:26577439
Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells. PMID:26575629
Meta-Analysis of DNA Tumor-Viral Integration Site Selection Indicates a Role for Repeats, Gene Expression and Epigenetics. PMID:26569308
The pig X and Y Chromosomes: structure, sequence, and evolution. PMID:26560630
Union Exon Based Approach for RNA-Seq Gene Quantification: To Be or Not to Be? PMID:26559532
dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs. PMID:26555599
DASHR: database of small human noncoding RNAs. PMID:26553799
Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells. PMID:26550473
A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients. PMID:26549855
Long noncoding RNAs in T lymphocytes. PMID:26538526
Using Population Genetics to Interrogate the Monogenic Nephrotic Syndrome Diagnosis in a Case Cohort. PMID:26534921
Differential expression analysis of human endogenous retroviruses based on ENCODE RNA-seq data. PMID:26530187
The Clinical Relevance of Long Non-Coding RNAs in Cancer. PMID:26516918
How to Use SNP_TATA_Comparator to Find a Significant Change in Gene Expression Caused by the Regulatory SNP of This Gene's Promoter via a Change in Affinity of the TATA-Binding Protein for This Promoter. PMID:26516624
Multiple SNP Set Analysis for Genome-Wide Association Studies Through Bayesian Latent Variable Selection. PMID:26515609
CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors. PMID:26510915
Genetics of RA susceptibility, what comes next? PMID:26509058
Protective alleles and modifier variants in human health and disease. PMID:26503796
Discovery and characterization of Alu repeat sequences via precise local read assembly. PMID:26503250
Promoter-like epigenetic signatures in exons displaying cell type-specific splicing. PMID:26498677
Evidence of Extensive Alternative Splicing in Post Mortem Human Brain HTT Transcription by mRNA Sequencing. PMID:26496077
The potential clinical impact of the release of two drafts of the human proteome. PMID:26496066
DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs. PMID:26493208
Cancer Specific Long Noncoding RNAs Show Differential Expression Patterns and Competing Endogenous RNA Potential in Hepatocellular Carcinoma. PMID:26492393
CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment. PMID:26491539
Third party annotation gene data set of eutherian lysozyme genes. PMID:26484105
Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity. PMID:26483626
Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells. PMID:26480000
Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. PMID:26472073
Genome-wide DNA methylome reveals the dysfunction of intronic microRNAs in major psychosis. PMID:26462620
lncRScan-SVM: A Tool for Predicting Long Non-Coding RNAs Using Support Vector Machine. PMID:26437338
Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families. PMID:26437029
Alternative Splicing QTLs in European and African Populations. PMID:26430802
Linking RNA biology to lncRNAs. PMID:26430155
Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer. PMID:26426411
Transcriptome sequencing and analysis of major genes involved in calcium signaling pathways in pear plants (Pyrus calleryana Decne.). PMID:26424153
Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort. PMID:26411346
Extracellular vesicle-mediated transfer of processed and functional RNY5 RNA. PMID:26392588
BIDCHIPS: bias decomposition and removal from ChIP-seq data clarifies true binding signal and its functional correlates. PMID:26388941
Using mixtures of biological samples as process controls for RNA-sequencing experiments. PMID:26383878
A survey of tandem repeat instabilities and associated gene expression changes in 35 colorectal cancers. PMID:26376692
Devising a Consensus Framework for Validation of Novel Human Coding Loci. PMID:26367542
Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction. PMID:26366811
Co-LncRNA: investigating the lncRNA combinatorial effects in GO annotations and KEGG pathways based on human RNA-Seq data. PMID:26363020
Identification and validation of potential prognostic lncRNA biomarkers for predicting survival in patients with multiple myeloma. PMID:26362431
Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum. PMID:26343451
Tracking Distinct RNA Populations Using Efficient and Reversible Covalent Chemistry. PMID:26340425
Comparison of stranded and non-stranded RNA-seq transcriptome profiling and investigation of gene overlap. PMID:26334759
Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms. PMID:26331722
Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies. PMID:26320941
Architectural and Functional Commonalities between Enhancers and Promoters. PMID:26317464
LARVA: an integrative framework for large-scale analysis of recurrent variants in noncoding annotations. PMID:26304545
Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions. PMID:26300125
Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes. PMID:26300000
Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans. PMID:26297486
Bioinformatics Methods and Tools to Advance Clinical Care. Findings from the Yearbook 2015 Section on Bioinformatics and Translational Informatics. PMID:26293864
Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. PMID:26293461
Evolution of the unspliced transcriptome. PMID:26289325
Read clouds uncover variation in complex regions of the human genome. PMID:26286554
piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammals. PMID:26283688
Systematic chromatin state comparison of epigenomes associated with diverse properties including sex and tissue type. PMID:26282110
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA. PMID:26278472
Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression. PMID:26274327
An Association Rule Mining Approach to Discover lncRNAs Expression Patterns in Cancer Datasets. PMID:26273587
Predicting effective microRNA target sites in mammalian mRNAs. PMID:26267216
Next-generation analysis of gene expression regulation--comparing the roles of synthesis and degradation. PMID:26259698
A gene-based association method for mapping traits using reference transcriptome data. PMID:26258848
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth. PMID:26258633
Nuclear Fractionation Reveals Thousands of Chromatin-Tethered Noncoding RNAs Adjacent to Active Genes. PMID:26257179
The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing. PMID:26253700
Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer. PMID:26253570
Paradigm shifts in genomics through the FANTOM projects. PMID:26253466
A reanalysis of mouse ENCODE comparative gene expression data. PMID:26236466
Integrated analysis of mRNA and miRNA expression in response to interleukin-6 in hepatocytes. PMID:26217794
BayesPI-BAR: a new biophysical model for characterization of regulatory sequence variations. PMID:26202972
Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data. PMID:26201343
Low-frequency germline variants across 6p22.2-6p21.33 are associated with non-obstructive azoospermia in Han Chinese men. PMID:26199320
Creating reference gene annotation for the mouse C57BL6/J genome assembly. PMID:26187010
Data quality aware analysis of differential expression in RNA-seq with NOISeq R/Bioc package. PMID:26184878
A potential signature of eight long non-coding RNAs predicts survival in patients with non-small cell lung cancer. PMID:26183581
Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells--Evidence of unique microRNA cargos. PMID:26176991
Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder. PMID:26173477
MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del. PMID:26173148
RNA editing differently affects protein-coding genes in D. melanogaster and H. sapiens. PMID:26169954
A semi-supervised approach uncovers thousands of intragenic enhancers differentially activated in human cells. PMID:26169177
Long non-coding RNAs in innate and adaptive immunity. PMID:26166759
Revealing Missing Human Protein Isoforms Based on Ab Initio Prediction, RNA-seq and Proteomics. PMID:26156868
Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III. PMID:26151409
Comparison of Gene Coexpression Profiles and Construction of Conserved Gene Networks to Find Functional Modules. PMID:26147120
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. PMID:26132169
Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species. PMID:26129847
Comparison of GENCODE and RefSeq gene annotation and the impact of reference geneset on variant effect prediction. PMID:26110515
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. PMID:26109357
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction. PMID:26109056
SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing. PMID:26104761
Dysregulated transcription across diverse cancer types reveals the importance of RNA-binding protein in carcinogenesis. PMID:26100984
Possible Human Papillomavirus 38 Contamination of Endometrial Cancer RNA Sequencing Samples in The Cancer Genome Atlas Database. PMID:26085148
Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells. PMID:26084335
Natural variability of minimotifs in 1092 people indicates that minimotifs are targets of evolution. PMID:26068475
Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity. PMID:26061969
Alternatively Spliced Homologous Exons Have Ancient Origins and Are Highly Expressed at the Protein Level. PMID:26061177
A general concept for consistent documentation of computational analyses. PMID:26055099
Recurrent somatic mutations in regulatory regions of human cancer genomes. PMID:26053494
Non-coding RNAs: Epigenetic regulators of bone development and homeostasis. PMID:26039869
RNA biomarkers to facilitate the identification of aggressive prostate cancer. PMID:26022941
JAFFA: High sensitivity transcriptome-focused fusion gene detection. PMID:26019724
Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy. PMID:26015570
Spatial genomic heterogeneity within localized, multifocal prostate cancer. PMID:26005866
StarScan: a web server for scanning small RNA targets from degradome sequencing data. PMID:25990732
APPRIS WebServer and WebServices. PMID:25990727
Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events. PMID:25985263
Seq2pathway: an R/Bioconductor package for pathway analysis of next-generation sequencing data. PMID:25979472
Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human aging. PMID:25977295
Recursive splicing in long vertebrate genes. PMID:25970246
Human genomics. The human transcriptome across tissues and individuals. PMID:25954002
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. PMID:25954001
Initial description of primate-specific cystine-knot Prometheus genes and differential gene expansions of D-dopachrome tautomerase genes. PMID:25941635
Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci. PMID:25939698
Low-frequency coding variants at 6p21.33 and 20q11.21 are associated with lung cancer risk in Chinese populations. PMID:25937444
A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation. PMID:25923108
Genetic code evolution reveals the neutral emergence of mutational robustness, and information as an evolutionary constraint. PMID:25919033
Inosine modifications in human tRNAs are incorporated at the precursor tRNA level. PMID:25916855
Cross-population joint analysis of eQTLs: fine mapping and functional annotation. PMID:25906321
ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin. PMID:25905630
Expression and functions of long noncoding RNAs during human T helper cell differentiation. PMID:25903499
Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex. PMID:25903279
Characterization and identification of hidden rare variants in the human genome. PMID:25903059
Applying the new genomics to alcohol dependence. PMID:25896098
Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants. PMID:25878728
The Landscape of long noncoding RNA classification. PMID:25869999
Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic. PMID:25869805
RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells. PMID:25858977
miRGate: a curated database of human, mouse and rat miRNA-mRNA targets. PMID:25858286
Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project. PMID:25854118
Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging. PMID:25853883
Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma. PMID:25848750
The lncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression. PMID:25843708
Disease-Associated Single-Nucleotide Polymorphisms From Noncoding Regions in Juvenile Idiopathic Arthritis Are Located Within or Adjacent to Functional Genomic Elements of Human Neutrophils and CD4+ T Cells. PMID:25833190
A thesaurus of genetic variation for interrogation of repetitive genomic regions. PMID:25820428
Re-annotation of presumed noncoding disease/trait-associated genetic variants by integrative analyses. PMID:25819875
SCAN database: facilitating integrative analyses of cytosine modification and expression QTL. PMID:25818895
Predicting the functions of long noncoding RNAs using RNA-seq based on Bayesian network. PMID:25815337
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in chronic lymphocytic leukemia. PMID:25787252
Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers. PMID:25768983
A comprehensive evaluation of ensembl, RefSeq, and UCSC annotations in the context of RNA-seq read mapping and gene quantification. PMID:25765860
GASS: genome structural annotation for Eukaryotes based on species similarity. PMID:25764973
Using the ENCODE Resource for Functional Annotation of Genetic Variants. PMID:25762420
Designing optogenetically controlled RNA for regulating biological systems. PMID:25758022
Systematic identification and characterization of long intergenic non-coding RNAs in fetal porcine skeletal muscle development. PMID:25753296
Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. PMID:25751143
Interferon-alpha competing endogenous RNA network antagonizes microRNA-1270. PMID:25746225
Prognostic impact of HOTAIR expression is restricted to ER-negative breast cancers. PMID:25739705
Most highly expressed protein-coding genes have a single dominant isoform. PMID:25732134
A survey of imprinted gene expression in mouse trophoblast stem cells. PMID:25711832
LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data. PMID:25707511
Genome-Wide Identification and Classification of MicroRNAs Derived from Repetitive Elements. PMID:25705168
Oncotator: cancer variant annotation tool. PMID:25703262
Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases. PMID:25695269
Epigenomic footprints across 111 reference epigenomes reveal tissue-specific epigenetic regulation of lincRNAs. PMID:25691256
Novel long non-coding RNAs are specific diagnostic and prognostic markers for prostate cancer. PMID:25686826
An integrative analysis of TFBS-clustered regions reveals new transcriptional regulation models on the accessible chromatin landscape. PMID:25682954
Joint annotation of chromatin state and chromatin conformation reveals relationships among domain types and identifies domains of cell-type-specific expression. PMID:25677182
Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells. PMID:25652794
Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets. PMID:25642422
An Island-Based Approach for Differential Expression Analysis. PMID:25632406
Correlation of circular RNA abundance with proliferation--exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues. PMID:25624062
Long Non-Coding RNA BST2/BISPR is Induced by IFN and Regulates the Expression of the Antiviral Factor Tetherin. PMID:25620967
3USS: a web server for detecting alternative 3'UTRs from RNA-seq experiments. PMID:25617413
The landscape of long noncoding RNAs in the human transcriptome. PMID:25599403
A method for calculating probabilities of fitness consequences for point mutations across the human genome. PMID:25599402
Kleat: cleavage site analysis of transcriptomes. PMID:25592595
Identifying mutation specific cancer pathways using a structurally resolved protein interaction network. PMID:25592571
Enhanced transcriptome maps from multiple mouse tissues reveal evolutionary constraint in gene expression. PMID:25582907
A long non-coding RNA links calreticulin-mediated immunogenic cell removal to RB1 transcription. PMID:25579178
Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions. PMID:25572935
Genome-wide discovery of human splicing branchpoints. PMID:25561518
Long non-coding RNAs as regulators of the endocrine system. PMID:25560704
Biased allelic expression in human primary fibroblast single cells. PMID:25557783
Uncapped 5' ends of mRNAs targeted by cytoplasmic capping map to the vicinity of downstream CAGE tags. PMID:25541487
Uncovering RNA Editing Sites in Long Non-Coding RNAs. PMID:25538940
Recombinant renewable polyclonal antibodies. PMID:25530082
Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson's disease. PMID:25528190
Long non-coding RNA normalisers in human brain tissue. PMID:25528156
Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. PMID:25527639
Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature. PMID:25524025
Comprehensive discovery of DNA motifs in 349 human cells and tissues reveals new features of motifs. PMID:25505144
Computational approaches to interpreting genomic sequence variation. PMID:25473426
Proteome sequencing goes deep. PMID:25461719
Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins. PMID:25436857
The RCSB Protein Data Bank: views of structural biology for basic and applied research and education. PMID:25428375
The UCSC Genome Browser database: 2015 update. PMID:25428374
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity. PMID:25419237
Population genetic simulations of complex phenotypes with implications for rare variant association tests. PMID:25417809
Type I Interferon Regulates the Expression of Long Non-Coding RNAs. PMID:25414701
Comparison of the transcriptional landscapes between human and mouse tissues. PMID:25413365
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. PMID:25411453
RADIA: RNA and DNA integrated analysis for somatic mutation detection. PMID:25405470
Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes. PMID:25403180
LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs. PMID:25399417
Splicing mutation analysis reveals previously unrecognized pathways in lymph node-invasive breast cancer. PMID:25394353
Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes. PMID:25387709
Systems biology approaches for studying the pathogenesis of non-alcoholic fatty liver disease. PMID:25386055
Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types. PMID:25383969
Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers. PMID:25383968
A stationary wavelet entropy-based clustering approach accurately predicts gene expression. PMID:25383910
Transcriptome analysis of the human corneal endothelium. PMID:25377225
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex. PMID:25375876
Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line. PMID:25373145
Small and Long Regulatory RNAs in the Immune System and Immune Diseases. PMID:25368617
Understanding gene regulatory mechanisms by integrating ChIP-seq and RNA-seq data: statistical solutions to biological problems. PMID:25364758
Genenames.org: the HGNC resources in 2015. PMID:25361968
Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity. PMID:25359165
Proteogenomics: concepts, applications and computational strategies. PMID:25357241
Ensembl 2015. PMID:25352552
RNAcentral: an international database of ncRNA sequences. PMID:25352543
SeAMotE: a method for high-throughput motif discovery in nucleic acid sequences. PMID:25341390
lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs. PMID:25332394
VAS: a convenient web portal for efficient integration of genomic features with millions of genetic variants. PMID:25306238
MUSIC: identification of enriched regions in ChIP-Seq experiments using a mappability-corrected multiscale signal processing framework. PMID:25292436
Promoter analysis reveals globally differential regulation of human long non-coding RNA and protein-coding genes. PMID:25275320
Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation. PMID:25274727
FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer. PMID:25273974
Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes. PMID:25264628
Long non-coding RNAs and control of gene expression in the immune system. PMID:25262537
lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6. PMID:25253741
High-resolution transcriptome analysis with long-read RNA sequencing. PMID:25251678
PLEK: a tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme. PMID:25239089
Long non-coding RNAs as a source of new peptides. PMID:25233276
LncRBase: an enriched resource for lncRNA information. PMID:25233092
Novel copy-number variants in a population-based investigation of classic heterotaxy. PMID:25232849
Resetting transcription factor control circuitry toward ground-state pluripotency in human. PMID:25215486
The landscape of kinase fusions in cancer. PMID:25204415
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism. PMID:25201977
Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy. PMID:25193853
Transcriptome sequencing of a large human family identifies the impact of rare noncoding variants. PMID:25192044
Advances in translational biomedicine from systems approaches. PMID:25177342
Frameshift alignment: statistics and post-genomic applications. PMID:25172925
The architecture of a scrambled genome reveals massive levels of genomic rearrangement during development. PMID:25171416
Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. PMID:25159147
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. PMID:25150838
Identification of genetic variants associated with alternative splicing using sQTLseekeR. PMID:25140736
Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants. PMID:25133550
Long noncoding RNA associated-competing endogenous RNAs in gastric cancer. PMID:25124853
Complex interactions of transcription factors in mediating cytokine biology in T cells. PMID:25123282
Negative regulation of the interferon response by an interferon-induced long non-coding RNA. PMID:25122750
Down-regulation of long non-coding RNA GAS5 is associated with the prognosis of hepatocellular carcinoma. PMID:25120813
Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer. PMID:25116943
Alternative forms of Y-box binding protein 1 and YB-1 mRNA. PMID:25116735
Identification of copy number variants from exome sequence data. PMID:25102989
Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia. PMID:25083870
SNP@lincTFBS: an integrated database of polymorphisms in human LincRNA transcription factor binding sites. PMID:25075616
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation. PMID:25074712
A wavelet approach to detect enriched regions and explore epigenomic landscapes. PMID:25072902
Missing genetic risk in neural tube defects: can exome sequencing yield an insight? PMID:25044326
Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites. PMID:25034687
Data integration in the era of omics: current and future challenges. PMID:25032990
Identification and characterization of long intergenic non-coding RNAs related to mouse liver development. PMID:25012394
Exploring the stability of long intergenic non-coding RNA in K562 cells by comparative studies of RNA-Seq datasets. PMID:24996425
Coherent somatic mutation in autoimmune disease. PMID:24988487
The effect of homozygous deletion of the BBOX1 and Fibin genes on carnitine level and acyl carnitine profile. PMID:24986124
EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promotes NSCLC cell proliferation and metastasis by affecting the epithelial-mesenchymal transition. PMID:24967960
Defining a personal, allele-specific, and single-molecule long-read transcriptome. PMID:24961374
The emerging era of genomic data integration for analyzing splice isoform function. PMID:24951248
Choice of transcripts and software has a large effect on variant annotation. PMID:24944579
Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes. PMID:24939910
Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease. PMID:24936207
Human 45,X fibroblast transcriptome reveals distinct differentially expressed genes including long noncoding RNAs potentially associated with the pathophysiology of Turner syndrome. PMID:24932682
Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs. PMID:24929436
Capture and Amplification by Tailing and Switching (CATS). An ultrasensitive ligation-independent method for generation of DNA libraries for deep sequencing from picogram amounts of DNA and RNA. PMID:24922482
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing. PMID:24920534
Structured RNAs and synteny regions in the pig genome. PMID:24917120
Genome-wide identification of long intergenic noncoding RNA genes and their potential association with domestication in pigs. PMID:24891613
Computational approaches for isoform detection and estimation: good and bad news. PMID:24885830
Genetic distance as an alternative to physical distance for definition of gene units in association studies. PMID:24884992
Integrative transcriptome meta-analysis reveals widespread sex-biased gene expression at the human fetal-maternal interface. PMID:24867328
Deep sequencing of HIV-infected cells: insights into nascent transcription and host-directed therapy. PMID:24850744
A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization. PMID:24844982
Long non-coding RNAs in stem cells and cancer. PMID:24829860
Global view of enhancer-promoter interactome in human cells. PMID:24821768
Realistic artificial DNA sequences as negative controls for computational genomics. PMID:24803667
Using common variants to indicate cancer genes. PMID:24798945
A comprehensive resequence-analysis of 250 kb region of 8q24.21 in men of African ancestry. PMID:24783269
Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance. PMID:24777452
Genetic interactions affecting human gene expression identified by variance association mapping. PMID:24771767
Multi-ethnic fine-mapping of 14 central adiposity loci. PMID:24760767
Guidelines for investigating causality of sequence variants in human disease. PMID:24759409
Heat shock alters the expression of schizophrenia and autism candidate genes in an induced pluripotent stem cell model of the human telencephalon. PMID:24736721
TF2LncRNA: identifying common transcription factors for a list of lncRNA genes from ChIP-Seq data. PMID:24729968
Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-Seq and ESTs. PMID:24722185
A short guide to long non-coding RNA gene nomenclature. PMID:24716852
Evidence for the biogenesis of more than 1,000 novel human microRNAs. PMID:24708865
Identification and characterization of alternative splicing in parasitic nematode transcriptomes. PMID:24690220
The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity. PMID:24681886
Diversity and dynamics of the Drosophila transcriptome. PMID:24670639
Effects of cytosine methylation on transcription factor binding sites. PMID:24669864
Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing. PMID:24651478
Genome-guided transcript assembly by integrative analysis of RNA sequence data. PMID:24633242
The challenges and importance of structural variation detection in livestock. PMID:24600474
MARIS: method for analyzing RNA following intracellular sorting. PMID:24594682
Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs. PMID:24594072
AnaLysis of Expression on human chromosome 21, ALE-HSA21: a pilot integrated web resource. PMID:24573881
Exome-based mapping and variant prioritization for inherited Mendelian disorders. PMID:24560519
The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection. PMID:24516381
Differentiated human stem cells resemble fetal, not adult, β cells. PMID:24516164
A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events. PMID:24498085
The cleverSuite approach for protein characterization: predictions of structural properties, solubility, chaperone requirements and RNA-binding abilities. PMID:24493033
bwtool: a tool for bigWig files. PMID:24489365
Functional annotation of noncoding sequence variants. PMID:24487584
Combinatorial epigenetic patterns as quantitative predictors of chromatin biology. PMID:24472558
Exon identity crisis: disease-causing mutations that disrupt the splicing code. PMID:24456648
A survey of software for genome-wide discovery of differential splicing in RNA-Seq data. PMID:24447644
Single molecule fluorescence approaches shed light on intracellular RNAs. PMID:24417544
Revisiting the thrifty gene hypothesis via 65 loci associated with susceptibility to type 2 diabetes. PMID:24412096
Dissecting the expression landscape of RNA-binding proteins in human cancers. PMID:24410894
Constitutive patterns of gene expression regulated by RNA-binding proteins. PMID:24401680
Sebnif: an integrated bioinformatics pipeline for the identification of novel large intergenic noncoding RNAs (lincRNAs)--application in human skeletal muscle cells. PMID:24400097
CGAT: computational genomics analysis toolkit. PMID:24395753
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. PMID:24393600
Genomics of alternative splicing: evolution, development and pathophysiology. PMID:24378600
Feature-based classification of amino acid substitutions outside conserved functional protein domains. PMID:24348198
Comparative genomic analysis of eutherian ribonuclease A genes. PMID:24337645
Long non-coding RNAs and chromatin modifiers: their place in the epigenetic code. PMID:24335342
Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments. PMID:24335146
Transparency tools in gene patenting for informing policy and practice. PMID:24316644
The Vertebrate Genome Annotation browser 10 years on. PMID:24316575
DPRP: a database of phenotype-specific regulatory programs derived from transcription factor binding data. PMID:24302579
From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing. PMID:24299736
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. PMID:24297251
Genetic associations with 25-hydroxyvitamin D deficiency in HIV-1-infected youth: fine-mapping for the GC/DBP gene that encodes the vitamin D-binding protein. PMID:24294218
Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs. PMID:24289259
Locus Reference Genomic: reference sequences for the reporting of clinically relevant sequence variants. PMID:24285302
Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma. PMID:24280290
The UCSC Genome Browser database: 2014 update. PMID:24270787
Genetic and epigenetic regulation of human lincRNA gene expression. PMID:24268656
Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification. PMID:24265805
Systematically differentiating functions for alternatively spliced isoforms through integrating RNA-seq data. PMID:24244129
Identification of novel transcripts and noncoding RNAs in bovine skin by deep next generation sequencing. PMID:24225384
Many human accelerated regions are developmental enhancers. PMID:24218637
Current status and new features of the Consensus Coding Sequence database. PMID:24217909
Regulatory Roles for Long ncRNA and mRNA. PMID:24216986
Finding the active genes in deep RNA-seq gene expression studies. PMID:24215113
SelenoDB 2.0: annotation of selenoprotein genes in animals and their genetic diversity in humans. PMID:24194593
Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH. PMID:24185839
Assessment of transcript reconstruction methods for RNA-seq. PMID:24185837
A genome-wide association study of prostate cancer in West African men. PMID:24185611
Large-scale mass spectrometric detection of variant peptides resulting from nonsynonymous nucleotide differences. PMID:24175627
Functional transcriptomics in the post-ENCODE era. PMID:24172201
Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps. PMID:24170599
Transcriptome interrogation of human myometrium identifies differentially expressed sense-antisense pairs of protein-coding and long non-coding RNA genes in spontaneous labor at term. PMID:24168098
Long non-coding RNA HOTAIR in carcinogenesis and metastasis. PMID:24165275
Gene regulation by non-coding RNAs. PMID:24164576
An emerging role for long non-coding RNA dysregulation in neurological disorders. PMID:24129177
A single-molecule long-read survey of the human transcriptome. PMID:24108091
Transcriptome comparison of human neurons generated using induced pluripotent stem cells derived from dental pulp and skin fibroblasts. PMID:24098394
Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expression. PMID:24068946
Transcriptome and genome sequencing uncovers functional variation in humans. PMID:24037378
Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division. PMID:24026178
Noncoding RNA in oncogenesis: a new era of identifying key players. PMID:24013378
Principles of self-organization in biological pathways: a hypothesis on the autogenous association of alpha-synuclein. PMID:24003031
Dynamic regulation of the transcription initiation landscape at single nucleotide resolution during vertebrate embryogenesis. PMID:24002785
Web Apollo: a web-based genomic annotation editing platform. PMID:24000942
Finding the lost treasures in exome sequencing data. PMID:23972387
Transcriptomic signatures in cartilage ageing. PMID:23971731
A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes. PMID:23966869
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor. PMID:23942233
Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR. PMID:23936419
Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation. PMID:23903355
Computational approaches to identify functional genetic variants in cancer genomes. PMID:23900255
Detecting and comparing non-coding RNAs in the high-throughput era. PMID:23887659
Transcription factor binding profiles reveal cyclic expression of human protein-coding genes and non-coding RNAs. PMID:23874175
Assessing association between protein truncating variants and quantitative traits. PMID:23860716
dbNSFP v2.0: a database of human non-synonymous SNVs and their functional predictions and annotations. PMID:23843252
Chromatin-bound RNA and the neurobiology of psychiatric disease. PMID:23831425
Dissecting the Characteristics and Dynamics of Human Protein Complexes at Transcriptome Cascade Using RNA-Seq Data. PMID:23824284
Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PMID:23818866
Transcriptome analysis of human tissues and cell lines reveals one dominant transcript per gene. PMID:23815980
Food, nutrigenomics, and neurodegeneration--neuroprotection by what you eat! PMID:23813102
Analysis of long non-coding RNA expression profiles in gastric cancer. PMID:23801869
Separating homeologs by phasing in the tetraploid wheat transcriptome. PMID:23800085
A probabilistic approach to learn chromatin architecture and accurate inference of the NF-κB/RelA regulatory network using ChIP-Seq. PMID:23771139
The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes. PMID:23729657
A brief review on the Human Encyclopedia of DNA Elements (ENCODE) project. PMID:23722115
A statistical framework for power calculations in ChIP-seq experiments. PMID:23665773
Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs. PMID:23637635
Discovery and mass spectrometric analysis of novel splice-junction peptides using RNA-Seq. PMID:23629695
Genomics and proteomics in solving brain complexity. PMID:23615871
Peppy: proteogenomic search software. PMID:23614390
Conserved expression of natural antisense transcripts in mammals. PMID:23577827
Comprehensive characterization of human genome variation by high coverage whole-genome sequencing of forty four Caucasians. PMID:23577066
A new method for stranded whole transcriptome RNA-seq. PMID:23557989
Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy. PMID:23533785
Long noncoding RNAs: new players in the molecular mechanism for maintenance and differentiation of pluripotent stem cells. PMID:23528033
Genomic and epigenomic insights into nutrition and brain disorders. PMID:23503168
Transcriptional regulation and its misregulation in disease. PMID:23498934
Non-Coding RNAs: Functional Aspects and Diagnostic Utility in Oncology. PMID:23455466
Accurate identification and analysis of human mRNA isoforms using deep long read sequencing. PMID:23450794
Incorporating the human gene annotations in different databases significantly improved transcriptomic and genetic analyses. PMID:23431329
Inference of natural selection from interspersed genomic elements based on polymorphism and divergence. PMID:23386628
Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data. PMID:23382893
Regulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and function. PMID:23337534
DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs. PMID:23193281
ENCODE data in the UCSC Genome Browser: year 5 update. PMID:23193274
APPRIS: annotation of principal and alternative splice isoforms. PMID:23161672
Uniting ENCODE with genome-wide proteomics. PMID:23138303
A fish-specific transposable element shapes the repertoire of p53 target genes in zebrafish. PMID:23118857
STAR: ultrafast universal RNA-seq aligner. PMID:23104886
Differentially expressed, variant U1 snRNAs regulate gene expression in human cells. PMID:23070852
Annotation of functional variation in personal genomes using RegulomeDB. PMID:22955989
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. PMID:22955988
Linking disease associations with regulatory information in the human genome. PMID:22955986
Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements. PMID:22955985
Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome. PMID:22955982
Understanding transcriptional regulation by integrative analysis of transcription factor binding data. PMID:22955978
Toward mapping the biology of the genome. PMID:22955973
What does our genome encode? PMID:22955972
Decoding the human genome. PMID:22955971
The long-range interaction landscape of gene promoters. PMID:22955621
Landscape of transcription in human cells. PMID:22955620
The accessible chromatin landscape of the human genome. PMID:22955617
An integrated encyclopedia of DNA elements in the human genome. PMID:22955616
The GENCODE pseudogene resource. PMID:22951037
GENCODE reference annotation for the human and mouse genomes PubMed citations: 778.

778 articles citing: GENCODE reference annotation for the human and mouse genomes

Potential Roles of Long Noncoding RNAs as Therapeutic Targets in Organ Transplantation. PMID:35359941
Myopia Genetics and Heredity. PMID:35327754
CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML. PMID:35326705
Clr-f expression regulates kidney immune and metabolic homeostasis. PMID:35318366
Incorporating regulatory interactions into gene-set analyses for GWAS data: A controlled analysis with the MAGMA tool. PMID:35316269
ADARs act as potent regulators of circular transcriptome in cancer. PMID:35314703
Gene-Based Analysis Reveals Sex-Specific Genetic Risk Factors of COPD. PMID:35308900
Pervasive occurrence of splice-site-creating mutations and their possible involvement in genetic disorders. PMID:35304488
Targeted long-read sequencing reveals clonally expanded HBV-associated chromosomal translocations in patients with chronic hepatitis B. PMID:35295767
Airway epithelial Paraoxonase-2 in obese asthma. PMID:35286330
Integrative analysis reveals a lineage-specific circular RNA landscape for adipo-osteogenesis of human mesenchymal stem cells. PMID:35279206
Dysregulation of Human Somatic piRNA Expression in Parkinson's Disease Subtypes and Stages. PMID:35269612
Chromatin Remodeler Smarca5 Is Required for Cancer-Related Processes of Primary Cell Fitness and Immortalization. PMID:35269430
A single-cell transcriptomic landscape of innate and adaptive intratumoral immunity in triple negative breast cancer during chemo- and immunotherapies. PMID:35260564
Reducing N6AMT1-mediated 6mA DNA modification promotes breast tumor progression via transcriptional repressing cell cycle inhibitors. PMID:35256595
Signatures of genetic variation in human microRNAs point to processes of positive selection and population-specific disease risks. PMID:35249174
Selective chemical tracking of Dnmt1 catalytic activity in live cells. PMID:35245449
An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer. PMID:35243422
Designing sensitive viral diagnostics with machine learning. PMID:35241837
Enhanced protein isoform characterization through long-read proteogenomics. PMID:35241129
Somatic and Germline Variant Calling from Next-Generation Sequencing Data. PMID:35230682
Neuronal-glial communication perturbations in murine SOD1G93A spinal cord. PMID:35228715
In heart failure reactivation of RNA-binding proteins is associated with the expression of 1,523 fetal-specific isoforms. PMID:35226669
Novel long non-coding RNAs of relevance for ulcerative colitis pathogenesis. PMID:35224318
The Complexity of the Mammalian Transcriptome. PMID:35220563
Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells. PMID:35216346
Distinct Minor Splicing Patterns across Cancers. PMID:35205431
Characterization of Alternative Splicing Events in Porcine Skeletal Muscles with Different Intramuscular Fat Contents. PMID:35204660
Protein prediction for trait mapping in diverse populations. PMID:35202437
Identification of the gene expression changes and gene regulatory aspects in ELF3 mutant bladder cancer. PMID:35199247
Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity. PMID:35198907
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. PMID:35197628
Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis. PMID:35197475
Low-input RNase footprinting for simultaneous quantification of cytosolic and mitochondrial translation. PMID:35193938
Does rapid sequence divergence preclude RNA structure conservation in vertebrates? PMID:35188540
Partial Monosomy 21 Mirrors Gene Expression of Trisomy 21 in a Patient-Derived Neuroepithelial Stem Cell Model. PMID:35186010
Rare coding variants in RCN3 are associated with blood pressure. PMID:35183128
Genome Sequencing for Genetics Diagnosis of Patients With Intellectual Disability: The DEFIDIAG Study. PMID:35178068
Endogenous retroviruses co-opted as divergently transcribed regulatory elements shape the regulatory landscape of embryonic stem cells. PMID:35166831
Identification of Early-Onset Metastasis in SF3B1 Mutated Uveal Melanoma. PMID:35159112
A New Strategy to Identify ceRNA-Based CCDC144NL-AS1/SERPINE1 Regulatory Axis as a Novel Prognostic Biomarker for Stomach Adenocarcinoma via High Throughput Transcriptome Data Mining and Computational Verification. PMID:35155200
Transcriptomic analysis reveals myometrial topologically associated domains linked to the onset of human term labour. PMID:35150271
Efficient in vitro and in vivo RNA editing via recruitment of endogenous ADARs using circular guide RNAs. PMID:35145312
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study. PMID:35144613
Mass cytometric and transcriptomic profiling of epithelial-mesenchymal transitions in human mammary cell lines. PMID:35140234
Comparison of Two Illumina Whole Transcriptome RNA Sequencing Library Preparation Methods Using Human Cancer FFPE Specimens. PMID:35138205
RNA sequencing on muscle biopsy from a 5-week bed rest study reveals the effect of exercise and potential interactions with dorsal root ganglion neurons. PMID:35133080
Mouse genomic and cellular annotations. PMID:35124726
PΨFinder: a practical tool for the identification and visualization of novel pseudogenes in DNA sequencing data. PMID:35114952
Systematic comparative analysis of strand-specific RNA-seq library preparation methods for low input samples. PMID:35110572
Prdm6 controls heart development by regulating neural crest cell differentiation and migration. PMID:35108221
LncRNA-Chromatin Pull-Down Using Biotin-Conjugated DNA Probes. PMID:35103977
Comparative analysis of common alignment tools for single-cell RNA sequencing. PMID:35084033
Facioscapulohumeral dystrophy transcriptome signatures correlate with different stages of disease and are marked by different MRI biomarkers. PMID:35082321
Characterization of the COPD alveolar niche using single-cell RNA sequencing. PMID:35078977
Tissue-specific multi-omics analysis of atrial fibrillation. PMID:35064145
Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation. PMID:35061661
Correction of a Factor VIII genomic inversion with designer-recombinases. PMID:35058465
Clin.iobio: A Collaborative Diagnostic Workflow to Enable Team-Based Precision Genomics. PMID:35055388
Exosomal and Plasma Non-Coding RNA Signature Associated with Urinary Albumin Excretion in Hypertension. PMID:35055008
Genome-wide analysis of copy number variants and normal facial variation in a large cohort of Bantu Africans. PMID:35047866
Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve. PMID:35041643
Deriving Ranges of Optimal Estimated Transcript Expression due to Nonidentifiability. PMID:35041494
LncRNA functional annotation with improved false discovery rate achieved by disease associations. PMID:35035785
Methyl-lysine readers PHF20 and PHF20L1 define two distinct gene expression-regulating NSL complexes. PMID:35033534
Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a). PMID:35027752
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches. PMID:35021063
Automated prediction of the clinical impact of structural copy number variations. PMID:35017614
Enhancer RNA Expression in Response to Glucocorticoid Treatment in Murine Macrophages. PMID:35011590
Profiling transcription factor activity dynamics using intronic reads in time-series transcriptome data. PMID:35007289
ATXN2-mediated translation of TNFR1 promotes esophageal squamous cell carcinoma via m6A-dependent manner. PMID:34995801
Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits. PMID:34995504
RNA sequencing and its applications in cancer and rare diseases. PMID:34988891
Robust T cell activation requires an eIF3-driven burst in T cell receptor translation. PMID:34970966
9-ING-41, a Small Molecule Inhibitor of GSK-3β, Potentiates the Effects of Chemotherapy on Colorectal Cancer Cells. PMID:34955846
Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance. PMID:34951957
Integration of high-resolution promoter profiling assays reveals novel, cell type-specific transcription start sites across 115 human cell and tissue types. PMID:34949670
GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data. PMID:34949163
Immunosenescence in Choroidal Neovascularization (CNV)-Transcriptional Profiling of Naïve and CNV-Associated Retinal Myeloid Cells during Aging. PMID:34948115
Attention-Based Deep Multiple-Instance Learning for Classifying Circular RNA and Other Long Non-Coding RNA. PMID:34946967
Comprehensive Analysis of Large-Scale Transcriptomes from Multiple Cancer Types. PMID:34946814
TMEM176B Regulates AKT/mTOR Signaling and Tumor Growth in Triple-Negative Breast Cancer. PMID:34943938
What is beyond LncRNAs in breast cancer: A special focus on colon cancer-associated Transcript-1 (CCAT-1). PMID:34938928
Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families. PMID:34937932
CTCF-mediated chromatin looping provides a topological framework for the formation of phase-separated transcriptional condensates. PMID:34931241
Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids. PMID:34930826
CCR5 and Biological Complexity: The Need for Data Integration and Educational Materials to Address Genetic/Biological Reductionism at the Interface of Ethical, Legal, and Social Implications. PMID:34925370
Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with global and local ancestries. PMID:34919805
TBX1 functions as a putative oncogene of breast cancer through promoting cell cycle progression. PMID:34919666
Regulation of retinal amacrine cell generation by miR-216b and Foxn3. PMID:34919141
The Prognostic Value and Immune Landscapes of a m6A/m5C/m1A-Related LncRNAs Signature in Head and Neck Squamous Cell Carcinoma. PMID:34917609
R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability. PMID:34916496
SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes. PMID:34903581
SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response. PMID:34901782
Emerging Roles of Long Noncoding RNAs in Immuno-Oncology. PMID:34900986
Analysis of Eukaryotic lincRNA Sequences Indicates Signatures of Hindered Translation Linked to Selection Pressure. PMID:34897509
Lyl-1 regulates primitive macrophages and microglia development. PMID:34887504
The Role of Long Non-Coding RNAs (lncRNAs) in Female Oriented Cancers. PMID:34885213
Variable expression of eighteen common housekeeping genes in human non-cancerous kidney biopsies. PMID:34882702
Natural SINEUP RNAs in Autism Spectrum Disorders: RAB11B-AS1 Dysregulation in a Neuronal CHD8 Suppression Model Leads to RAB11B Protein Increase. PMID:34880900
GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1. PMID:34880217
Identifying the temporal electrophysiological and molecular changes that contribute to TSC-associated epileptogenesis. PMID:34877936
ProteoDisco: A flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies. PMID:34864882
Compendium of human transcription factor effector domains. PMID:34863368
HIF-Dependent NFATC1 Activation Upregulates ITGA5 and PLAUR in Intestinal Epithelium in Inflammatory Bowel Disease. PMID:34858489
Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug. PMID:34857016
RNA editing regulates lncRNA splicing in human early embryo development. PMID:34851956
CRISPRroots: on- and off-target assessment of RNA-seq data in CRISPR-Cas9 edited cells. PMID:34850137
Accurate expression quantification from nanopore direct RNA sequencing with NanoCount. PMID:34850115
recount3: summaries and queries for large-scale RNA-seq expression and splicing. PMID:34844637
Diagnostic Accuracy of Liquid Biopsy in Endometrial Cancer. PMID:34830891
DNA Methylation Signature in Mononuclear Cells and Proinflammatory Cytokines May Define Molecular Subtypes in Sporadic Meniere Disease. PMID:34829759
Molecular Classification and Interpretation of Amyotrophic Lateral Sclerosis Using Deep Convolution Neural Networks and Shapley Values. PMID:34828360
Decoding the Equine Genome: Lessons from ENCODE. PMID:34828313
Regulatory noncoding RNAs: potential biomarkers and therapeutic targets in acute myeloid leukemia. PMID:34824883
The telomere length landscape of prostate cancer. PMID:34824250
LSD1 inhibition sustains T cell invigoration with a durable response to PD-1 blockade. PMID:34819502
A renal cell carcinoma tumorgraft platform to advance precision medicine. PMID:34818533
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions. PMID:34815394
Disruption of β-Catenin-Dependent Wnt Signaling in Colon Cancer Cells Remodels the Microenvironment to Promote Tumor Invasion. PMID:34799404
Machine learning of genomic features in organotropic metastases stratifies progression risk of primary tumors. PMID:34795255
Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage. PMID:34795242
Genetic fusions favor tumorigenesis through degron loss in oncogenes. PMID:34795215
EHMT2 suppresses the variation of transcriptional switches in the mouse embryo. PMID:34793451
lncRNAfunc: a knowledgebase of lncRNA function in human cancer. PMID:34791419
MMP-9 drives the melanomagenic transcription program through histone H3 tail proteolysis. PMID:34785776
TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes. PMID:34779419
Macrophage Selenoproteins Restrict Intracellular Replication of Francisella tularensis and Are Essential for Host Immunity. PMID:34777335
A single-cell atlas of chromatin accessibility in the human genome. PMID:34774128
RNA in formation and regulation of transcriptional condensates. PMID:34772787
AI applications in functional genomics. PMID:34765093
Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells. PMID:34764293
Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease. PMID:34764283
Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. PMID:34762911
Global RNA editing identification and characterization during human pluripotent-to-cardiomyocyte differentiation. PMID:34760335
Three-dimensional genome organization via triplex-forming RNAs. PMID:34759378
APPRIS: selecting functionally important isoforms. PMID:34755885
CSC software corrects off-target mediated gRNA depletion in CRISPR-Cas9 essentiality screens. PMID:34753924
Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination. PMID:34751268
Pol3Base: a resource for decoding the interactome, expression, evolution, epitranscriptome and disease variations of Pol III-transcribed ncRNAs. PMID:34747466
Application of long-read sequencing to elucidate complex pharmacogenomic regions: a proof of principle. PMID:34741133
BDdb: a comprehensive platform for exploration and utilization of birth defect multi-omics data. PMID:34736471
Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency. PMID:34731163
Identification of high-confidence human poly(A) RNA isoform scaffolds using nanopore sequencing. PMID:34728536
Haplotype-aware variant calling with PEPPER-Margin-DeepVariant enables high accuracy in nanopore long-reads. PMID:34725481
The Predictive Role of Immune Related Subgroup Classification in Immune Checkpoint Blockade Therapy for Lung Adenocarcinoma. PMID:34721552
Identification of Epithelial-Mesenchymal Transition- (EMT-) Related LncRNA for Prognostic Prediction and Risk Stratification in Esophageal Squamous Cell Carcinoma. PMID:34712369
Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci. PMID:34699533
Identifying Protein Interactomes of Target RNAs Using HyPR-MS. PMID:34694612
The Resolved Mutual Information Function as a Structural Fingerprint of Biomolecular Sequences for Interpretable Machine Learning Classifiers. PMID:34682081
Single-Cell RNA-Seq Reveals Heterogeneous lncRNA Expression in Xenografted Triple-Negative Breast Cancer Cells. PMID:34681087
Alternative Splicing Mechanisms Underlying Opioid-Induced Hyperalgesia. PMID:34680965
A Multi-mRNA Prognostic Signature for Anti-TNFα Therapy Response in Patients with Inflammatory Bowel Disease. PMID:34679598
Embryonic LTR retrotransposons supply promoter modules to somatic tissues. PMID:34675070
eccDNAs are apoptotic products with high innate immunostimulatory activity. PMID:34671165
PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands. PMID:34667079
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer. PMID:34663921
Comprehensive Genomic Characterization Analysis Identifies an Oncogenic Pseudogene RP11-3543B.1 in Human Gastric Cancer. PMID:34660601
Hyper-IgE Syndrome due to an Elusive Novel Intronic Homozygous Variant in DOCK8. PMID:34657245
Tyrosine phosphatases regulate resistance to ALK inhibitors in ALK+ anaplastic large cell lymphoma. PMID:34657149
RNA Sequencing Data for FFPE Tumor Blocks Can Be Used for Robust Estimation of Tumor Mutation Burden in Individual Biosamples. PMID:34650919
Segmentation and genome annotation algorithms for identifying chromatin state and other genomic patterns. PMID:34648491
Gene.iobio: an interactive web tool for versatile, clinically-driven variant interrogation and prioritization. PMID:34645894
TIGER: The gene expression regulatory variation landscape of human pancreatic islets. PMID:34644572
A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. PMID:34644528
Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae. PMID:34642700
Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT. PMID:34637399
SomaMutDB: a database of somatic mutations in normal human tissues. PMID:34634815
Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesis. PMID:34622232
Mapping and modeling the genomic basis of differential RNA isoform expression at single-cell resolution with LR-Split-seq. PMID:34620214
Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas. PMID:34617407
Epigenomic diversity of cortical projection neurons in the mouse brain. PMID:34616065
Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization. PMID:34615539
Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain. PMID:34610312
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation. PMID:34609283
SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment. PMID:34608315
Identification of Mutation Landscape and Immune Cell Component for Liver Hepatocellular Carcinoma Highlights Potential Therapeutic Targets and Prognostic Markers. PMID:34603396
Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASR complex in mouse models. PMID:34599184
Gene Expression Nebulas (GEN): a comprehensive data portal integrating transcriptomic profiles across multiple species at both bulk and single-cell levels. PMID:34591957
Chemical capping improves template switching and enhances sequencing of small RNAs. PMID:34581823
Ladostigil Attenuates Induced Oxidative Stress in Human Neuroblast-like SH-SY5Y Cells. PMID:34572436
Distinct gene-set burden patterns underlie common generalized and focal epilepsies. PMID:34571366
TransLnc: a comprehensive resource for translatable lncRNAs extends immunopeptidome. PMID:34570220
Identification of Novel Single-Nucleotide Variants With Potential of Mediating Malfunction of MicroRNA in Congenital Heart Disease. PMID:34568467
Integrating Genetic and Transcriptomic Data to Reveal Pathogenesis and Prognostic Markers of Pancreatic Adenocarcinoma. PMID:34567094
Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome. PMID:34561431
Multiomics Analysis of Neuroblastoma Cells Reveals a Diversity of Malignant Transformations. PMID:34557494
Designing libraries for pooled CRISPR functional screens of long noncoding RNAs. PMID:34533605
Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo. PMID:34522901
Activation of Hippo signaling pathway mediates mitochondria dysfunction and dilated cardiomyopathy in mice. PMID:34522223
Molecular Profiling of Coronavirus Disease 2019 (COVID-19) Autopsies Uncovers Novel Disease Mechanisms. PMID:34506752
Usp22 Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice. PMID:34503086
Construction on of a Ferroptosis-Related lncRNA-Based Model to Improve the Prognostic Evaluation of Gastric Cancer Patients Based on Bioinformatics. PMID:34497636
Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients. PMID:34496298
Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors. PMID:34493726
Elucidating the Molecular Mechanism of Ischemic Stroke Using Integrated Analysis of miRNA, mRNA, and lncRNA Expression Profiles. PMID:34483854
Mendelian randomization study of interleukin (IL)-1 family and lung cancer. PMID:34475499
Differential transcript usage analysis of bulk and single-cell RNA-seq data with DTUrtle. PMID:34469510
Investigation of LINC00493/SMIM26 Gene Suggests Its Dual Functioning at mRNA and Protein Level. PMID:34445188
LINC01133 Inhibits Invasion and Promotes Proliferation in an Endometriosis Epithelial Cell Line. PMID:34445100
Metatranscriptomic Analysis of Bacterial Communities on Laundered Textiles: A Pilot Case Study. PMID:34442670
The landscape of alternative polyadenylation in single cells of the developing mouse embryo. PMID:34429411
miQC: An adaptive probabilistic framework for quality control of single-cell RNA-sequencing data. PMID:34428202
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis. PMID:34426578
INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants. PMID:34425882
Illuminating lncRNA Function Through Target Prediction. PMID:34417758
Characterizing miRNA-lncRNA Interplay. PMID:34417757
An integrin αEβ7-dependent mechanism of IgA transcytosis requires direct plasma cell contact with intestinal epithelium. PMID:34417548
DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. PMID:34413299
RNA sequencing reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes. PMID:34407998
A strategy for building and using a human reference pangenome. PMID:34386196
Positive predictive value highlights four novel candidates for actionable genetic screening from analysis of 220,000 clinicogenomic records. PMID:34385667
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. PMID:34381026
Diffusion enables integration of heterogeneous data and user-driven learning in a desktop knowledge-base. PMID:34379637
The molecular basis, genetic control and pleiotropic effects of local gene co-expression. PMID:34376650
Extracellular CIRP Induces an Inflammatory Phenotype in Pulmonary Fibroblasts via TLR4. PMID:34367191
Cloud Computing Based Immunopeptidomics Utilizing Community Curated Variant Libraries Simplifies and Improves Neo-Antigen Discovery in Metastatic Melanoma. PMID:34359654
Transcriptional landscape of cellular networks reveal interactions driving the dormancy mechanisms in cancer. PMID:34349126
Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes. PMID:34340684
Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes. PMID:34338636
An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer. PMID:34326322
Analysis of gene expression and mutation data points on contribution of transcription to the mutagenesis by APOBEC enzymes. PMID:34316712
Cancer LncRNA Census 2 (CLC2): an enhanced resource reveals clinical features of cancer lncRNAs. PMID:34316704
Putatively cancer-specific exon-exon junctions are shared across patients and present in developmental and other non-cancer cells. PMID:34316681
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer. PMID:34312968
RNA-Sequencing Analysis of Differentially Expressed Genes in Human iPSC-Derived Cardiomyocytes. PMID:34302660
The clinical importance of tandem exon duplication-derived substitutions. PMID:34302486
Expanding studies of chromosome structure and function in the era of T2T genomics. PMID:34302168
Altered splicing associated with the pathology of inflammatory bowel disease. PMID:34301333
Single-cell alternative polyadenylation analysis delineates GABAergic neuron types. PMID:34301239
Role of Long Non-Coding RNAs and the Molecular Mechanisms Involved in Insulin Resistance. PMID:34298896
A Panel of rSNPs Demonstrating Allelic Asymmetry in Both ChIP-seq and RNA-seq Data and the Search for Their Phenotypic Outcomes through Analysis of DEGs. PMID:34298860
Ranked Choice Voting for Representative Transcripts with TRaCE. PMID:34297055
Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice. PMID:34289377
Transcriptome-Wide Association Study for Inflammatory Bowel Disease Reveals Novel Candidate Susceptibility Genes in Specific Colon Subsites and Tissue Categories. PMID:34286847
Hairpin sequence and structure is associated with features of isomiR biogenesis. PMID:34286662
Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma. PMID:34286278
Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity. PMID:34284134
A pan-cancer landscape of somatic mutations in non-unique regions of the human genome. PMID:34282324
Effect of substrate stiffness on human intestinal enteroids' infectivity by enteroaggregative Escherichia coli. PMID:34280559
Traces of SARS-CoV-2 RNA in Peripheral Blood Cells of Patients with COVID-19. PMID:34280038
HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing. PMID:34274995
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion. PMID:34272367
An ancestral recombination graph of human, Neanderthal, and Denisovan genomes. PMID:34272242
Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision between Stem Cell Maintenance and Differentiation. PMID:34266896
SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency. PMID:34266387
Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells. PMID:34262050
Accurate transcriptome assembly by Nanopore RNA sequencing reveals novel functional transcripts in hepatocellular carcinoma. PMID:34255396
tRNA-like leader-trailer interaction promotes 3'-end maturation of MALAT1. PMID:34253686
Long reads capture simultaneous enhancer-promoter methylation status for cell-type deconvolution. PMID:34252972
JEDI: circular RNA prediction based on junction encoders and deep interaction among splice sites. PMID:34252942
A functional genomic approach to identify reference genes for human pancreatic beta cell real-time quantitative RT-PCR analysis. PMID:34241569
[Expression profile of intervertebral disc degeneration-specific genes: a transcriptome sequencing-based analysis]. PMID:34238741
High-content single-cell combinatorial indexing. PMID:34226710
Comprehensive Analysis of RNA Expression Correlations between Biofluids and Human Tissues. PMID:34207420
Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex. PMID:34198071
Characterization of Human Genes Modulated by Porphyromonas gingivalis Highlights the Ribosome, Hypothalamus, and Cholinergic Neurons. PMID:34194426
Cytoplasmic long noncoding RNAs are differentially regulated and translated during human neuronal differentiation. PMID:34193551
RNA sequencing reveals potential interacting networks between the altered transcriptome and ncRNome in the skeletal muscle of diabetic mice. PMID:34190986
m6 A modification of HSATIII lncRNAs regulates temperature-dependent splicing. PMID:34184765
Srsf3 mediates alternative RNA splicing downstream of PDGFRα signaling in the facial mesenchyme. PMID:34184034
Direct long-read RNA sequencing identifies a subset of questionable exitrons likely arising from reverse transcription artifacts. PMID:34183059
Expression of Retroelements in Mammalian Gametes and Embryos. PMID:34182464
Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay. PMID:34181717
SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity. PMID:34172724
Memory CD8 T Cells Generated by Cytomegalovirus Vaccine Vector Expressing NKG2D Ligand Have Effector-Like Phenotype and Distinct Functional Features. PMID:34168650
Pseudogenes as Biomarkers and Therapeutic Targets in Human Cancers. PMID:34165724
Pseudogene Profiling for Cancer Subtype Classification. PMID:34165723
GENCODE Pseudogenes. PMID:34165709
Computational Methods for Pseudogene Annotation Based on Sequence Homology. PMID:34165707
Single cell derived mRNA signals across human kidney tumors. PMID:34162837
Bioinformatics Pipeline to Analyze lncRNA Arrays. PMID:34160798
LncRNAs and Available Databases. PMID:34160796
Spike-in normalization for single-cell RNA-seq reveals dynamic global transcriptional activity mediating anticancer drug response. PMID:34159316
Comprehensive identification of transposable element insertions using multiple sequencing technologies. PMID:34158502
Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning. PMID:34157120
RNA Network Interactions During Differentiation of Human Trophoblasts. PMID:34150771
Low Energy Electron Irradiation Is a Potent Alternative to Gamma Irradiation for the Inactivation of (CAR-)NK-92 Cells in ATMP Manufacturing. PMID:34149724
The RNA Atlas expands the catalog of human non-coding RNAs. PMID:34140680
Pan-cancer characterization of lncRNA modifiers of immune microenvironment reveals clinically distinct de novo tumor subtypes. PMID:34140519
Hypoxia-Induced miR-148a Downregulation Contributes to Poor Survival in Colorectal Cancer. PMID:34135940
Transcriptomic Signature Differences Between SARS-CoV-2 and Influenza Virus Infected Patients. PMID:34135895
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins. PMID:34133714
Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner. PMID:34130712
Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ. PMID:34128467
Dissecting the multi-omics atlas of the exosomes released by human lung adenocarcinoma stem-like cells. PMID:34127680
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity. PMID:34119711
NORAD-induced Pumilio phase separation is required for genome stability. PMID:34108682
FnCas9-based CRISPR diagnostic for rapid and accurate detection of major SARS-CoV-2 variants on a paper strip. PMID:34106048
MOCCASIN: a method for correcting for known and unknown confounders in RNA splicing analysis. PMID:34099673
catRAPID omics v2.0: going deeper and wider in the prediction of protein-RNA interactions. PMID:34086933
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. PMID:34083488
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns. PMID:34080738
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. PMID:34078885
Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair. PMID:34078594
Immune and repair responses in joint tissues and lymph nodes after knee arthroplasty surgery in mice. PMID:34076292
The Detection and Bioinformatic Analysis of Alternative 3' UTR Isoforms as Potential Cancer Biomarkers. PMID:34070203
Mechanisms of TP53 Pathway Inactivation in Embryonic and Somatic Cells-Relevance for Understanding (Germ Cell) Tumorigenesis. PMID:34065345
ncFANs v2.0: an integrative platform for functional annotation of non-coding RNAs. PMID:34050762
Pretraining model for biological sequence data. PMID:34050350
Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2. PMID:34047695
Assessing the functional relevance of splice isoforms. PMID:34046593
Genetic effects on liver chromatin accessibility identify disease regulatory variants. PMID:34038741
The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency. PMID:34033652
Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung. PMID:34030460
Discovery of Plasma Membrane-Associated RNAs through APEX-seq. PMID:34028638
The nuclear periphery is a scaffold for tissue-specific enhancers. PMID:34023908
Long-read whole-genome methylation patterning using enzymatic base conversion and nanopore sequencing. PMID:34019650
Interpretation of T cell states from single-cell transcriptomics data using reference atlases. PMID:34017005
Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education. PMID:34014253
imPlatelet classifier: image-converted RNA biomarker profiles enable blood-based cancer diagnostics. PMID:34013585
Chrom-Lasso: a lasso regression-based model to detect functional interactions using Hi-C data. PMID:34013331
Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT. PMID:34003794
A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival. PMID:34002017
Landscape of allele-specific transcription factor binding in the human genome. PMID:33980847
Bisulphite miRNA-seq reveals widespread CpG and non-CpG 5-(hydroxy)methyl-Cytosine in human microRNAs. PMID:33980133
Genetic and epigenetic features of promoters with ubiquitous chromatin accessibility support ubiquitous transcription of cell-essential genes. PMID:33978759
SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes. PMID:33976134
Co-transcriptional splicing efficiencies differ within genes and between cell types. PMID:33975916
Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome. PMID:33971925
Exact transcript quantification over splice graphs. PMID:33971903
Combination of Immune-Related Genomic Alterations Reveals Immune Characterization and Prediction of Different Prognostic Risks in Ovarian Cancer. PMID:33968933
Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints. PMID:33968050
Cold-induction of afadin in brown fat supports its thermogenic capacity. PMID:33963248
TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs. PMID:33961797
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy. PMID:33958760
EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape. PMID:33956915
Trips-Viz: an environment for the analysis of public and user-generated ribosome profiling data. PMID:33950201
Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved alternative splicing nonsense-mediated decay pathways. PMID:33941243
The long and the short of it: unlocking nanopore long-read RNA sequencing data with short-read differential expression analysis tools. PMID:33937765
SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductor-powered RNA-seq analyses. PMID:33932985
The impact of cell type and context-dependent regulatory variants on human immune traits. PMID:33926512
Expression and regulatory roles of lncRNAs in G-CIMP-low vs G-CIMP-high Glioma: an in-silico analysis. PMID:33926464
Long Non-Coding RNA CRNDE Is Involved in Resistance to EGFR Tyrosine Kinase Inhibitor in EGFR-Mutant Lung Cancer via eIF4A3/MUC1/EGFR Signaling. PMID:33924522
Identification of Potential Key lncRNAs in the Context of Mouse Myeloid Differentiation by Systematic Transcriptomics Analysis. PMID:33922442
Pathway analysis for genome-wide genetic variation data: Analytic principles, latest developments, and new opportunities. PMID:33896739
A unified atlas of CD8 T cell dysfunctional states in cancer and infection. PMID:33891860
Increased expression of peptides from non-coding genes in cancer proteomics datasets suggests potential tumor neoantigens. PMID:33888849
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer. PMID:33886505
The cis-regulatory effects of modern human-specific variants. PMID:33885362
Spatiotemporal transcriptional dynamics of the cycling mouse oviduct. PMID:33864778
Loss of coordinated expression between ribosomal and mitochondrial genes revealed by comprehensive characterization of a large family with a rare Mendelian disorder. PMID:33862179
A form of muscular dystrophy associated with pathogenic variants in JAG2. PMID:33861953
The control of polycomb repressive complexes by long noncoding RNAs. PMID:33861025
Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets. PMID:33859189
CytoTalk: De novo construction of signal transduction networks using single-cell transcriptomic data. PMID:33853780
A long non-coding RNAs expression signature to improve prognostic prediction of Wilms tumor in children. PMID:33850811
Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model. PMID:33850167
Transcript Identification Through Long-Read Sequencing. PMID:33835462
Databases for RNA Editing Collections. PMID:33835458
Targeting non-coding RNAs for the treatment of retinal diseases. PMID:33815941
Regulation of TGFβ Signalling by TRPV4 in Chondrocytes. PMID:33805168
Musashi1 Contribution to Glioblastoma Development via Regulation of a Network of DNA Replication, Cell Cycle and Division Genes. PMID:33804958
Approaches to Identify and Characterise the Post-Transcriptional Roles of lncRNAs in Cancer. PMID:33803328
Non-Coding RNA Signatures of B-Cell Acute Lymphoblastic Leukemia. PMID:33799946
Artificial Sweeteners and Whole-Food Science: Could Mice Help Clinicians Make Diet Recommendations for IBD Patients? PMID:33798527
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development. PMID:33797837
Gene Tracer: A smart, interactive, voice-controlled Alexa skill for gene information retrieval and browsing, mutation annotation, and network visualization. PMID:33792640
Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. PMID:33789107
Protocol for comprehensive RNA sequencing analysis of murine long non-coding RNAs during aging. PMID:33786463
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. PMID:33771987
A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies. PMID:33771853
Breast tumours maintain a reservoir of subclonal diversity during expansion. PMID:33762732
Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling. PMID:33743191
Identification of Novel Pleiotropic SNPs Associated with Osteoporosis and Rheumatoid Arthritis. PMID:33740106
Inhibition of KDM1A activity restores adult neurogenesis and improves hippocampal memory in a mouse model of Kabuki syndrome. PMID:33738331
Boosting GWAS using biological networks: A study on susceptibility to familial breast cancer. PMID:33735170
Epigenetic Regulation of the N-Terminal Truncated Isoform of Matrix Metalloproteinase-2 (NTT-MMP-2) and Its Presence in Renal and Cardiac Diseases. PMID:33732288
Mutant non-coding RNA resource in mouse embryonic stem cells. PMID:33729986
Data-independent acquisition-based proteome and phosphoproteome profiling across six melanoma cell lines reveals determinants of proteotypes. PMID:33728422
A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets. PMID:33727337
Association between SNP rs527616 in lncRNA AQP4-AS1 and susceptibility to breast cancer in a southern Brazilian population. PMID:33721012
An immunoscore nomogram for predicting survival in patients with oesophageal cancer. PMID:33714960
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma. PMID:33711272
MAPKAP Kinase-2 Drives Expression of Angiogenic Factors by Tumor-Associated Macrophages in a Model of Inflammation-Induced Colon Cancer. PMID:33708191
Comprehensive profiling of circular RNAs with nanopore sequencing and CIRI-long. PMID:33707777
A two-stream convolutional neural network for microRNA transcription start site feature integration and identification. PMID:33707582
Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses. PMID:33693773
ZRSR1 co-operates with ZRSR2 in regulating splicing of U12-type introns in murine hematopoietic cells. PMID:33691379
Stepwise chromatin and transcriptional acquisition of an intraepithelial lymphocyte program. PMID:33686285
Higher Rates of Processed Pseudogene Acquisition in Humans and Three Great Apes Revealed by Long-Read Assemblies. PMID:33681998
SomatoSim: precision simulation of somatic single nucleotide variants. PMID:33676403
De novo structural mutation rates and gamete-of-origin biases revealed through genome sequencing of 2,396 families. PMID:33675682
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE. PMID:33674594
Proteomic and Transcriptomic Techniques to Decipher the Molecular Evolution of Venoms. PMID:33669432
Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum. PMID:33648633
Signaling-to-chromatin pathways in the immune system. PMID:33644906
Integrative analysis of genomic, epigenomic and transcriptomic data identified molecular subtypes of esophageal carcinoma. PMID:33638948
Enhanced Understanding of Molecular Interactions and Function Underlying Pain Processes Through Networks of Transcript Isoforms, Genes, and Gene Families. PMID:33633454
Haplotype-resolved diverse human genomes and integrated analysis of structural variation. PMID:33632895
Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer's disease. PMID:33630843
NK/ILC1 cells mediate neuroinflammation and brain pathology following congenital CMV infection. PMID:33630019
Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma. PMID:33626351
Transcriptomics analysis of Toxoplasma gondii-infected mouse macrophages reveals coding and noncoding signatures in the presence and absence of MyD88. PMID:33622246
Targeting Human lncRNAs for Treating Cardiometabolic Diseases. PMID:33608863
LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions. PMID:33602314
Ex vivo conditioning of peripheral blood mononuclear cells of diabetic patients promotes vasculogenic wound healing. PMID:33599112
Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data. PMID:33588838
Secreted Phosphoprotein 1 Expression in Retinal Mononuclear Phagocytes Links Murine to Human Choroidal Neovascularization. PMID:33585455
Proteogenomic and metabolomic characterization of human glioblastoma. PMID:33577785
Benchmark study comparing liftover tools for genome conversion of epigenome sequencing data. PMID:33575605
Factorial study of the RNA-seq computational workflow identifies biases as technical gene signatures. PMID:33575596
RNAsamba: neural network-based assessment of the protein-coding potential of RNA sequences. PMID:33575571
A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation. PMID:33575256
Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes. PMID:33575113
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. PMID:33568819
Breaking through the unknowns of the human reference genome. PMID:33568817
TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation. PMID:33554859
PACIFIC: a lightweight deep-learning classifier of SARS-CoV-2 and co-infecting RNA viruses. PMID:33547380
HiC-ACT: improved detection of chromatin interactions from Hi-C data via aggregated Cauchy test. PMID:33545029
Enhancers predominantly regulate gene expression during differentiation via transcription initiation. PMID:33539786
Elevated NSD3 histone methylation activity drives squamous cell lung cancer. PMID:33536620
PopDel identifies medium-size deletions simultaneously in tens of thousands of genomes. PMID:33526789
Gliadin, through the Activation of Innate Immunity, Triggers lncRNA NEAT1 Expression in Celiac Disease Duodenal Mucosa. PMID:33525473
Human pathways in animal models: possibilities and limitations. PMID:33524155
The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress. PMID:33523898
Identification of Potential Prognostic Competing Triplets in High-Grade Serous Ovarian Cancer. PMID:33519912
Identification of hub lncRNA ceRNAs in multiple sclerosis based on ceRNA mechanisms. PMID:33507382
Rapid 3D Bioprinting of Glioblastoma Model Mimicking Native Biophysical Heterogeneity. PMID:33502104
Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions. PMID:33495453
ncRNA BC1 influences translation in the oocyte. PMID:33491548
An integrated approach to determine the abundance, mutation rate and phylogeny of the SARS-CoV-2 genome. PMID:33479725
Large organized chromatin lysine domains help distinguish primitive from differentiated cell populations. PMID:33479238
Compression of quantification uncertainty for scRNA-seq counts. PMID:33471073
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain. PMID:33469025
A platform for curated products from novel open reading frames prompts reinterpretation of disease variants. PMID:33468550
Detection of aberrant gene expression events in RNA sequencing data. PMID:33462443
Long non-coding RNA review and implications in acute lung inflammation. PMID:33454366
Rad18 mediates specific mutational signatures and shapes the genomic landscape of carcinogen-induced tumors in vivo. PMID:33447826
Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. PMID:33437055
The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis. PMID:33435206
Exosome detection via the ultrafast-isolation system: EXODUS. PMID:33432243
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. PMID:33432195
Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference. PMID:33431880
Preprocessing choices affect RNA velocity results for droplet scRNA-seq data. PMID:33428615
Whole exome sequencing and establishment of an organoid culture of the carcinoma showing thymus-like differentiation (CASTLE) of the parotid gland. PMID:33415446
An integrated multi-omics approach to identify regulatory mechanisms in cancer metastatic processes. PMID:33413550
Interplay between host non-coding RNAs and influenza viruses. PMID:33404285
Failure to replicate the association of rare loss-of-function variants in type I IFN immunity genes with severe COVID-19. PMID:33398295
Adaptation to Endoplasmic Reticulum Stress Enhances Resistance of Oral Cancer Cells to Cisplatin by Up-Regulating Polymerase η and Increasing DNA Repair Efficiency. PMID:33396303
Preclinical techniques to investigate exercise training in vascular pathophysiology. PMID:33385323
Transcriptomic Analysis of Naïve Human Embryonic Stem Cells Cultured in Three-Dimensional PEG Scaffolds. PMID:33379237
The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells. PMID:33376132
The Paf1 complex positively regulates enhancer activity in mouse embryonic stem cells. PMID:33376128
Common cell type nomenclature for the mammalian brain. PMID:33372656
bsAS, an antisense long non-coding RNA, essential for correct wing development through regulation of blistered/DSRF isoform usage. PMID:33370262
Unraveling Targetable Systemic and Cell-Type-Specific Molecular Phenotypes of Alzheimer's and Parkinson's Brains With Digital Cytometry. PMID:33362460
Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit. PMID:33357414
Cerina: systematic circRNA functional annotation based on integrative analysis of ceRNA interactions. PMID:33335165
Exercise during pregnancy mitigates negative effects of parental obesity on metabolic function in adult mouse offspring. PMID:33332990
Drug Response Associated With and Prognostic lncRNAs Mediated by DNA Methylation and Transcription Factors in Colon Cancer. PMID:33329694
Anti-tumour immunity induces aberrant peptide presentation in melanoma. PMID:33328638
Annotation of Full-Length Long Noncoding RNAs with Capture Long-Read Sequencing (CLS). PMID:33326074
Liftoff: accurate mapping of gene annotations. PMID:33320174
Functional Screening Techniques to Identify Long Non-Coding RNAs as Therapeutic Targets in Cancer. PMID:33317042
Epigenomic differences in the human and chimpanzee genomes are associated with structural variation. PMID:33303495
Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria. PMID:33296702
Identification of a 6-Gene Signature Associated with Resistance to Tyrosine Kinase Inhibitors: Prognosis for Clear Cell Renal Cell Carcinoma. PMID:33296352
lncRNAs in T lymphocytes: RNA regulation at the heart of the immune response. PMID:33296288
A validated lineage-derived somatic truth data set enables benchmarking in cancer genome analysis. PMID:33293579
A long noncoding RNA, LncMyoD, modulates chromatin accessibility to regulate muscle stem cell myogenic lineage progression. PMID:33293420
Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing. PMID:33292386
Network and Evolutionary Analysis of Human Epigenetic Regulators to Unravel Disease Associations. PMID:33291839
Matrix stiffness epigenetically regulates the oncogenic activation of the Yes-associated protein in gastric cancer. PMID:33288878
Systematic Analyses of the Differentially Expressed Alternative Splicing Events in Gastric Cancer and Its Clinical Significance. PMID:33281863
SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature. PMID:33281748
Rare genetic variants in the gene encoding histone lysine demethylase 4C (KDM4C) and their contributions to susceptibility to schizophrenia and autism spectrum disorder. PMID:33279929
Meiotic Cells Counteract Programmed Retrotransposon Activation via RNA-Binding Translational Repressor Assemblies. PMID:33278343
Distinctive Features of Orbital Adipose Tissue (OAT) in Graves' Orbitopathy. PMID:33266331
MicroRNA-7a2 Regulates Prolactin in Developing Lactotrophs and Prolactinoma Cells. PMID:33248443
Evaluating the Genomic Parameters Governing rAAV-Mediated Homologous Recombination. PMID:33248247
Association between lincRNA expression and overall survival for patients with triple-negative breast cancer. PMID:33247368
The UCSC Genome Browser database: 2021 update. PMID:33221922
Are spliced ncRNA host genes distinct classes of lncRNAs? PMID:33219910
Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data. PMID:33219685
LincSNP 3.0: an updated database for linking functional variants to human long non-coding RNAs, circular RNAs and their regulatory elements. PMID:33219661
Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo. PMID:33217941
Asymmetron: a toolkit for the identification of strand asymmetry patterns in biological sequences. PMID:33211865
FANTOM enters 20th year: expansion of transcriptomic atlases and functional annotation of non-coding RNAs. PMID:33211864
Characterizing the function of EPB41L4A in the predisposition to papillary thyroid carcinoma. PMID:33203992
XPC deficiency increases risk of hematologic malignancies through mutator phenotype and characteristic mutational signature. PMID:33203900
Transcriptome Analysis Identifies SenZfp536, a Sense LncRNA that Suppresses Self-renewal of Cortical Neural Progenitors. PMID:33196962
Biomarker Discovery for the Carcinogenic Heterogeneity Between Colon and Rectal Cancers Based on lncRNA-Associated ceRNA Network Analysis. PMID:33194594
Deep learning based DNA:RNA triplex forming potential prediction. PMID:33183242
Progressive Cactus is a multiple-genome aligner for the thousand-genome era. PMID:33177663
The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice. PMID:33177522
Nonconserved Long Intergenic Noncoding RNAs Associate With Complex Cardiometabolic Disease Traits. PMID:33176448
Decoding myofibroblast origins in human kidney fibrosis. PMID:33176333
ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. PMID:33176148
Gramene 2021: harnessing the power of comparative genomics and pathways for plant research. PMID:33170273
Identification of Dominant Transcripts in Oxidative Stress Response by a Full-Length Transcriptome Analysis. PMID:33168698
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s. PMID:33144593
Expression of EMT-Related Genes in Hybrid E/M Colorectal Cancer Cells Determines Fibroblast Activation and Collagen Remodeling. PMID:33143259
Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity. PMID:33139957
Ensembl 2021. PMID:33137190
Analysis of open chromatin regions in bladder cancer links β-catenin mutations and Wnt signaling with neuronal subtype of bladder cancer. PMID:33122695
HeRA: an atlas of enhancer RNAs across human tissues. PMID:33119754
New Insights on the Mobility of Viral and Host Non-Coding RNAs Reveal Extracellular Vesicles as Intriguing Candidate Antiviral Targets. PMID:33114356
Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function. PMID:33113340
mTOR-dependent translation amplifies microglia priming in aging mice. PMID:33108356
REDIportal: millions of novel A-to-I RNA editing events from thousands of RNAseq experiments. PMID:33104797
Discover novel disease-associated genes based on regulatory networks of long-range chromatin interactions. PMID:33096239
A CRISPR and high-content imaging assay compliant with ACMG/AMP guidelines for clinical variant interpretation in ciliopathies. PMID:33095315
Beyond the RNA-dependent function of LncRNA genes. PMID:33095159
TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes. PMID:33091126
LocusFocus: Web-based colocalization for the annotation and functional follow-up of GWAS. PMID:33090994
Differential Modulation of Mouse Heart Gene Expression by Infection With Two Trypanosoma cruzi Strains: A Transcriptome Analysis. PMID:33088283
crisprSQL: a novel database platform for CRISPR/Cas off-target cleavage assays. PMID:33084893
Differences in maternal gene expression in Cesarean section delivery compared with vaginal delivery. PMID:33082495
Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing. PMID:33081811
Prediction of genome-wide effects of single nucleotide variants on transcription factor binding. PMID:33077858
TransCirc: an interactive database for translatable circular RNAs based on multi-omics evidence. PMID:33074314
Understand variability of COVID-19 through population and tissue variations in expression of SARS-CoV-2 host genes. PMID:33072849
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells. PMID:33057200
smORFunction: a tool for predicting functions of small open reading frames and microproteins. PMID:33054771
LncRNA Platr22 promotes super-enhancer activity and stem cell pluripotency. PMID:33049031
LncExpDB: an expression database of human long non-coding RNAs. PMID:33045751
Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes. PMID:33042023
tRFtarget: a database for transfer RNA-derived fragment targets. PMID:33035346
Involvement of circulating factors in the transmission of paternal experiences through the germline. PMID:33034389
Fattening chips: hypertrophy, feeding, and fasting of human white adipocytes in vitro. PMID:33034335
eIF2α controls memory consolidation via excitatory and somatostatin neurons. PMID:33029011
SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes. PMID:33024961
Discovery and Functional Prediction of Long Non-Coding RNAs Common to Ischemic Stroke and Myocardial Infarction. PMID:33024736
lncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA. PMID:33020484
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency. PMID:33020483
Automated Classification of Osteosarcoma and Benign Tumors using RNA-seq and Plain X-ray. PMID:33018194
An analysis of tissue-specific alternative splicing at the protein level. PMID:33017396
Pseudo2GO: A Graph-Based Deep Learning Method for Pseudogene Function Prediction by Borrowing Information From Coding Genes. PMID:33014009
A High-Resolution Map of Human Enhancer RNA Loci Characterizes Super-enhancer Activities in Cancer. PMID:33007258
Quantitative and time-resolved miRNA pattern of early human T cell activation. PMID:32990751
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice. PMID:32989316
Functional signatures of evolutionarily young CTCF binding sites. PMID:32988407
Tissue-specific usage of transposable element-derived promoters in mouse development. PMID:32988383
Enhancing site-specific DNA integration by a Cas9 nuclease fused with a DNA donor-binding domain. PMID:32986839
Potential role of cellular miRNAs in coronavirus-host interplay. PMID:32983652
A mouse tissue atlas of small noncoding RNA. PMID:32978296
LncMirNet: Predicting LncRNA-miRNA Interaction Based on Deep Learning of Ribonucleic Acid Sequences. PMID:32977679
FuncPEP: A Database of Functional Peptides Encoded by Non-Coding RNAs. PMID:32977531
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure. PMID:32969079
Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification. PMID:32964524
Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing. PMID:32962098
One locus with two roles: microRNA-independent functions of microRNA-host-gene locus-encoded long noncoding RNAs. PMID:32945142
Network analysis of KLF5 targets showing the potential oncogenic role of SNHG12 in colorectal cancer. PMID:32943987
Molecular characteristics associated with ferroptosis in hepatocellular carcinoma progression. PMID:32936424
DNA polymerase α interacts with H3-H4 and facilitates the transfer of parental histones to lagging strands. PMID:32923642
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. PMID:32917713
FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer. PMID:32888433
Conserved UBE3A subcellular distribution between human and mice is facilitated by non-homologous isoforms. PMID:32879944
Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance. PMID:32868340
An integrative proteogenomics approach reveals peptides encoded by annotated lincRNA in the mouse kidney inner medulla. PMID:32866085
Prognostic Molecular Signatures for Metastatic Potential in Clinically Low-Risk Stage I and II Clear Cell Renal Cell Carcinomas. PMID:32850445
Identification of Transcription Factor/Gene Axis in Colon Cancer Using a Methylome Approach. PMID:32849837
ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation. PMID:32848148
Circular DNA intermediates in the generation of large human segmental duplications. PMID:32847497
Integrated Dissection of lncRNA-Perturbated Triplets Reveals Novel Prognostic Signatures Across Cancer Types. PMID:32846981
Elucidating Epigenetic Regulation by Identifying Functional cis-Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage. PMID:32840049
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. PMID:32839606
FAM83H-AS1 is a potential modulator of cancer driver genes across different tumors and a prognostic marker for ER/PR + BRCA patients. PMID:32839509
PINCER: improved CRISPR/Cas9 screening by efficient cleavage at conserved residues. PMID:32821942
Cis and trans effects differentially contribute to the evolution of promoters and enhancers. PMID:32819422
ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition. PMID:32817962
Systematic identification of functional SNPs interrupting 3'UTR polyadenylation signals. PMID:32804959
Identification of Potential Prognostic Biomarkers for Breast Cancer Based on lncRNA-TF-Associated ceRNA Network and Functional Module. PMID:32802855
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency. PMID:32795400
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. PMID:32790644
Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions. PMID:32766783
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. PMID:32762776
Comparative genomic analysis of eutherian fibroblast growth factor genes. PMID:32758140
A lncRNA landscape in breast cancer reveals a potential role for AC009283.1 in proliferation and apoptosis in HER2-enriched subtype. PMID:32753692
Guidelines for human gene nomenclature. PMID:32747822
Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution. PMID:32747416
Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins. PMID:32745093
EDF1 coordinates cellular responses to ribosome collisions. PMID:32744497
Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories. PMID:32736380
Expanded encyclopaedias of DNA elements in the human and mouse genomes. PMID:32728249
Index and biological spectrum of human DNase I hypersensitive sites. PMID:32728217
Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer's disease. PMID:32727612
Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site. PMID:32726316
lncRNA_Mdeep: An Alignment-Free Predictor for Distinguishing Long Non-Coding RNAs from Protein-Coding Transcripts by Multimodal Deep Learning. PMID:32718000
A Pharmacological Interactome between COVID-19 Patient Samples and Human Sensory Neurons Reveals Potential Drivers of Neurogenic Pulmonary Dysfunction. PMID:32714114
RNA-Seq Analysis Reveals Localization-Associated Alternative Splicing across 13 Cell Lines. PMID:32708427
Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes. PMID:32703770
Circadian rhythm influences induction of trained immunity by BCG vaccination. PMID:32692732
Enhancer prediction in the human genome by probabilistic modelling of the chromatin feature patterns. PMID:32689977
3D genome organization contributes to genome instability at fragile sites. PMID:32680994
A long-read RNA-seq approach to identify novel transcripts of very large genes. PMID:32660935
Detecting fitness epistasis in recently admixed populations with genome-wide data. PMID:32652930
Glomerular endothelial cell heterogeneity in Alport syndrome. PMID:32651395
Network of clinically-relevant lncRNAs-mRNAs associated with prognosis of hepatocellular carcinoma patients. PMID:32636408
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer. PMID:32633781
Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM. PMID:32620816
A Chromatin Accessibility Atlas of the Developing Human Telencephalon. PMID:32610082
Competing Endogenous RNAs, Non-Coding RNAs and Diseases: An Intertwined Story. PMID:32605220
mitch: multi-contrast pathway enrichment for multi-omics and single-cell profiling data. PMID:32600408
The Roles of Long Noncoding RNAs HNF1α-AS1 and HNF4α-AS1 in Drug Metabolism and Human Diseases. PMID:32599764
Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples. PMID:32597303
SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes. PMID:32577641
Conserved Small Nucleotidic Elements at the Origin of Concerted piRNA Biogenesis from Genes and lncRNAs. PMID:32570966
Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells. PMID:32563258
The Chromatin Regulator ZMYM2 Restricts Human Pluripotent Stem Cell Growth and Is Essential for Teratoma Formation. PMID:32559458
Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences. PMID:32543182
PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation. PMID:32541091
Closing Human Reference Genome Gaps: Identifying and Characterizing Gap-Closing Sequences. PMID:32532800
SURF: integrative analysis of a compendium of RNA-seq and CLIP-seq datasets highlights complex governing of alternative transcriptional regulation by RNA-binding proteins. PMID:32532357
Fluent genomics with plyranges and tximeta. PMID:32528659
A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites. PMID:32522993
Compound Heterozygous Variants in Pediatric Cancers: A Systematic Review. PMID:32508881
The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impact on Translational Neuroimaging. PMID:32508601
Human gene and disease associations for clinical-genomics and precision medicine research. PMID:32508008
MALAT1 Long Non-Coding RNA: Functional Implications. PMID:32503170
GC-AG Introns Features in Long Non-coding and Protein-Coding Genes Suggest Their Role in Gene Expression Regulation. PMID:32499820
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. PMID:32499560
WHSC1 monomethylates histone H1 and induces stem-cell like features in squamous cell carcinoma of the head and neck. PMID:32497898
A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction. PMID:32497778
A tissue level atlas of the healthy human virome. PMID:32493363
Intrinsic Abnormalities of Cystic Fibrosis Airway Connective Tissue Revealed by an In Vitro 3D Stromal Model. PMID:32492951
BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C-deficient mice. PMID:32484798
Expression Quantitative Trait Loci (eQTL) Mapping in Korean Patients With Crohn's Disease and Identification of Potential Causal Genes Through Integration With Disease Associations. PMID:32477412
Brain-related genes are specifically enriched with long phase 1 introns. PMID:32470086
Transcript expression-aware annotation improves rare variant interpretation. PMID:32461655
A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging. PMID:32460027
Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer. PMID:32455980
Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype. PMID:32446964
Nuclear Parkin Activates the ERRα Transcriptional Program and Drives Widespread Changes in Gene Expression Following Hypoxia. PMID:32444656
RiboToolkit: an integrated platform for analysis and annotation of ribosome profiling data to decode mRNA translation at codon resolution. PMID:32427338
Identification of an Immune-Related Nine-lncRNA Signature Predictive of Overall Survival in Colon Cancer. PMID:32425969
FGviewer: an online visualization tool for functional features of human fusion genes. PMID:32421816
Progress, Challenges, and Surprises in Annotating the Human Genome. PMID:32421357
Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects. PMID:32408067
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver. PMID:32407006
βT87Q-Globin Gene Therapy Reduces Sickle Hemoglobin Production, Allowing for Ex Vivo Anti-sickling Activity in Human Erythroid Cells. PMID:32405513
Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells. PMID:32398033
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response. PMID:32396861
TGFam-Finder: a novel solution for target-gene family annotation in plants. PMID:32392385
A Novel 4-Gene Score to Predict Survival, Distant Metastasis and Response to Neoadjuvant Therapy in Breast Cancer. PMID:32370309
CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection. PMID:32358020
Investigating the effect of dependence between conditions with Bayesian Linear Mixed Models for motif activity analysis. PMID:32357166
REPIC: a database for exploring the N6-methyladenosine methylome. PMID:32345346
Psychiatric Disorders and lncRNAs: A Synaptic Match. PMID:32344798
rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments. PMID:32338139
The Challenges and Opportunities of LncRNAs in Ovarian Cancer Research and Clinical Use. PMID:32326249
Functional Profiling of FSH and Estradiol in Ovarian Granulosa Cell Tumors. PMID:32309755
LncRNA Functions as a New Emerging Epigenetic Factor in Determining the Fate of Stem Cells. PMID:32296461
Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia. PMID:32296054
Obstacles to detecting isoforms using full-length scRNA-seq data. PMID:32293520
The Sox2 transcription factor binds RNA. PMID:32286318
ATP7B variant c.1934T > G p.Met645Arg causes Wilson disease by promoting exon 6 skipping. PMID:32284880
Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing. PMID:32275660
CNGA3 acts as a cold sensor in hypothalamic neurons. PMID:32270761
EPIGENE: genome-wide transcription unit annotation using a multivariate probabilistic model of histone modifications. PMID:32264931
Using multiple reference genomes to identify and resolve annotation inconsistencies. PMID:32264824
Dynamic Expression of Long Non-Coding RNAs Throughout Parasite Sexual and Neural Maturation in Schistosoma japonicum. PMID:32244675
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma. PMID:32234056
To construct a ceRNA regulatory network as prognostic biomarkers for bladder cancer. PMID:32233022
A population-based approach for gene prioritization in understanding complex traits. PMID:32232557
Hardy-Weinberg Equilibrium in the Large Scale Genomic Sequencing Era. PMID:32231685
Integrated Informatics Analysis of Cancer-Related Variants. PMID:32228266
No evidence for DNA N 6-methyladenine in mammals. PMID:32206710
Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism. PMID:32197071
Pharmacological target-focused transcriptomic analysis of native vs cultured human and mouse dorsal root ganglia. PMID:32197039
Efficient identification of multiple pathways: RNA-Seq analysis of livers from 56Fe ion irradiated mice. PMID:32192433
An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation. PMID:32156728
Dnmt3a and Dnmt3b-Decommissioned Fetal Enhancers are Linked to Kidney Disease. PMID:32127410
Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons. PMID:32126975
IRF4 instructs effector Treg differentiation and immune suppression in human cancer. PMID:32125291
Millefy: visualizing cell-to-cell heterogeneity in read coverage of single-cell RNA sequencing datasets. PMID:32122302
Long non-coding RNAs in development and disease: conservation to mechanisms. PMID:32100288
Tximeta: Reference sequence checksums for provenance identification in RNA-seq. PMID:32097405
Recovering signals of ghost archaic introgression in African populations. PMID:32095519
Heparin-based hydrogel scaffolding alters the transcriptomic profile and increases the chemoresistance of MDA-MB-231 triple-negative breast cancer cells. PMID:32091043
A guide to naming human non-coding RNA genes. PMID:32090359
PVT1 Long Non-coding RNA in Gastrointestinal Cancer. PMID:32083000
Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci. PMID:32066938
Variability in estimated gene expression among commonly used RNA-seq pipelines. PMID:32066774
A Novel Prognostic Index Based on Alternative Splicing in Papillary Renal Cell Carcinoma. PMID:32063918
GREG-studying transcriptional regulation using integrative graph databases. PMID:32055858
Methplotlib: analysis of modified nucleotides from nanopore sequencing. PMID:32053166
Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis. PMID:32050897
Reviewing the Limitations of Adult Mammalian Cardiac Regeneration: Noncoding RNAs as Regulators of Cardiomyogenesis. PMID:32050588
Human Long Noncoding RNA Interactome: Detection, Characterization and Function. PMID:32033158
Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. PMID:32020063
An optimized chemical-genetic method for cell-specific metabolic labeling of RNA. PMID:32015544
Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts. PMID:31992710
Transcriptomic and open chromatin atlas of high-resolution anatomical regions in the rhesus macaque brain. PMID:31980617
Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides. PMID:31971508
Germline cancer predisposition variants and pediatric glioma: a population-based study in California. PMID:31970404
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1. PMID:31964861
A potential new mechanism for pregnancy loss: considering the role of LINE-1 retrotransposons in early spontaneous miscarriage. PMID:31964400
The most abundant maternal lncRNA Sirena1 acts post-transcriptionally and impacts mitochondrial distribution. PMID:31956907
The Missing "lnc" between Genetics and Cardiac Disease. PMID:31947625
The Influence of Met Receptor Level on HGF-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma. PMID:31940827
TP63 isoform expression is linked with distinct clinical outcomes in cancer. PMID:31927310
Widespread Dysregulation of Long Noncoding Genes Associated With Fatty Acid Metabolism, Cell Division, and Immune Response Gene Networks in Xenobiotic-exposed Rat Liver. PMID:31926019
Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein. PMID:31918411
Functional annotation of de novo variants from healthy individuals. PMID:31896246
Learning distributed representations of RNA and protein sequences and its application for predicting lncRNA-protein interactions. PMID:31890140
Few SINEs of life: Alu elements have little evidence for biological relevance despite elevated translation. PMID:31886458
Dynamic changes in intron retention are tightly associated with regulation of splicing factors and proliferative activity during B-cell development. PMID:31879760
Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression. PMID:31870430
CancerClock: A DNA Methylation Age Predictor to Identify and Characterize Aging Clock in Pan-Cancer. PMID:31867319
5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma. PMID:31852832
The MathIOmica Toolbox: General Analysis Utilities for Dynamic Omics Datasets. PMID:31851777
Monocytes and Monocyte-Derived Antigen-Presenting Cells Have Distinct Gene Signatures in Experimental Model of Multiple Sclerosis. PMID:31849962
Overcoming challenges and dogmas to understand the functions of pseudogenes. PMID:31848477
Profiles of Long Non-Coding RNAs and mRNA Expression in Human Macrophages Regulated by Interleukin-27. PMID:31835347
A developmental landscape of 3D-cultured human pre-gastrulation embryos. PMID:31830756
Logomaker: beautiful sequence logos in Python. PMID:31821414
GenoSurf: metadata driven semantic search system for integrated genomic datasets. PMID:31820804
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A. PMID:31814998
Current RNA-seq methodology reporting limits reproducibility. PMID:31813948
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis. PMID:31806906
Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection. PMID:31801078
Multimodal Long Noncoding RNA Interaction Networks: Control Panels for Cell Fate Specification. PMID:31796550
Detecting, Categorizing, and Correcting Coverage Anomalies of RNA-Seq Quantification. PMID:31786209
LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation. PMID:31782550
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations. PMID:31768671
A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary. PMID:31759823
High-resolution genome-wide expression analysis of single myofibers using SMART-Seq. PMID:31753917
Structural variant calling: the long and the short of it. PMID:31747936
A heterodimer of evolved designer-recombinases precisely excises a human genomic DNA locus. PMID:31745551
DIANA-LncBase v3: indexing experimentally supported miRNA targets on non-coding transcripts. PMID:31732741
Comparative genomic analysis of eutherian connexin genes. PMID:31729432
Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist. PMID:31729316
SyntDB: defining orthologues of human long noncoding RNAs across primates. PMID:31728519
A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2. PMID:31722198
Characterization of novel primary miRNA transcription units in human cells using Bru-seq nascent RNA sequencing. PMID:31709421
PyGMQL: scalable data extraction and analysis for heterogeneous genomic datasets. PMID:31703553
Ensembl 2020. PMID:31691826
EPD in 2020: enhanced data visualization and extension to ncRNA promoters. PMID:31680159
Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation during DNA Replication. PMID:31675501
NPInter v4.0: an integrated database of ncRNA interactions. PMID:31670377
Further evidence of involvement of TMEM132E in autosomal recessive nonsyndromic hearing impairment. PMID:31656313
Comprehensive Analysis of Human microRNA-mRNA Interactome. PMID:31649721
ExonSkipDB: functional annotation of exon skipping event in human. PMID:31642488
The Caenorhabditis elegans RIG-I Homolog DRH-1 Mediates the Intracellular Pathogen Response upon Viral Infection. PMID:31619561
RNA Expression Profiling of Lymphoepithelioma-Like Carcinoma of the Bladder Reveals a Basal-Like Molecular Subtype. PMID:31610173
A systematic evaluation of single cell RNA-seq analysis pipelines. PMID:31604912
QTLbase: an integrative resource for quantitative trait loci across multiple human molecular phenotypes. PMID:31598699
APAatlas: decoding alternative polyadenylation across human tissues. PMID:31586392
Debutant iOS app and gene-disease complexities in clinical genomics and precision medicine. PMID:31586224
Tolerance to Selenoprotein Loss Differs between Human and Mouse. PMID:31560400
Discovery of high-confidence human protein-coding genes and exons by whole-genome PhyloCSF helps elucidate 118 GWAS loci. PMID:31537640
LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly. PMID:31537638
IRES-mediated cap-independent translation, a path leading to hidden proteome. PMID:31504667
Cell-type-specific analysis of alternative polyadenylation using single-cell transcriptomics data. PMID:31501864
Interplay of LIS1 and MeCP2: Interactions and Implications With the Neurodevelopmental Disorders Lissencephaly and Rett Syndrome. PMID:31474834
Comprehensive transcriptomic analysis indicates brain regional specific alterations in type 2 diabetes. PMID:31449493
Long non-coding RNA CASC19 is associated with the progression and prognosis of advanced gastric cancer. PMID:31422382
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1. PMID:31409373
Nonparametric expression analysis using inferential replicate counts. PMID:31372651
Spatial chromatin architecture alteration by structural variations in human genomes at the population scale. PMID:31362752
An expanded landscape of human long noncoding RNA. PMID:31350901
Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages. PMID:31323189
Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis. PMID:31303496
Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome. PMID:31279658
Identification of HIV transmitting CD11c+ human epidermal dendritic cells. PMID:31227717
p73 regulates epidermal wound healing and induced keratinocyte programming. PMID:31216312
Comprehensive epigenetic analyses reveal master regulators driving lung metastasis of breast cancer. PMID:31215771
Computational Methods for Mapping, Assembly and Quantification for Coding and Non-coding Transcripts. PMID:31193391
Long noncoding RNA in cardiac aging and disease. PMID:31152659
LnCompare: gene set feature analysis for human long non-coding RNAs. PMID:31147707
A comparison of two workflows for regulome and transcriptome-based prioritization of genetic variants associated with myocardial mass. PMID:31145509
Circular RNAs as potential biomarkers and therapeutics for cardiovascular disease. PMID:31119072
Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight. PMID:31104630
Next-generation genome annotation: we still struggle to get it right. PMID:31097009
ARMOR: An Automated Reproducible MOdular Workflow for Preprocessing and Differential Analysis of RNA-seq Data. PMID:31088905
Predicting the change of exon splicing caused by genetic variant using support vector regression. PMID:31070294
Long Noncoding RNAs in Host-Pathogen Interactions. PMID:31053495
RIG-I Activation by a Designer Short RNA Ligand Protects Human Immune Cells against Dengue Virus Infection without Causing Cytotoxicity. PMID:31043531
Non-Coding RNAs as New Therapeutic Targets in the Context of Renal Fibrosis. PMID:31018516
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis. PMID:31015462
Comprehensive analysis of differentially expressed profiles and reconstruction of a competing endogenous RNA network in papillary renal cell carcinoma. PMID:30957192
The role of ABCA7 in Alzheimer's disease: evidence from genomics, transcriptomics and methylomics. PMID:30903345
Cellular Gene Expression during Hepatitis C Virus Replication as Revealed by Ribosome Profiling. PMID:30875926
Genomic Characterization of the Zinc Transcriptional Regulatory Element Reveals Potential Functional Roles of ZNF658. PMID:30734197
The 26th annual Nucleic Acids Research database issue and Molecular Biology Database Collection. PMID:30626175
The European Bioinformatics Institute in 2018: tools, infrastructure and training. PMID:30445657
GENCODE 2021 PubMed citations: 52.

52 articles citing: GENCODE 2021

Identification of miRNA biomarkers for stomach adenocarcinoma. PMID:35578189
Comprehensive Analysis of Long Noncoding RNA Modified by m6A Methylation in Oxidative and Glycolytic Skeletal Muscles. PMID:35562992
Skin-Expressing lncRNAs in Inflammatory Responses. PMID:35559048
Comprehensive Analysis of Subtypes and Identification of Key lncRNAs Based on Glutamine Metabolism-Related Long Noncoding RNAs. PMID:35529265
Comprehensive Analysis of lncRNA Expression Profile and the Potential Role of ENST00000604491 in Graves' Disease. PMID:35509980
"Pseudo-pseudogenes" in bacterial genomes: Proteogenomics reveals a wide but low protein expression of pseudogenes in Salmonella enterica. PMID:35489061
Micro-dissection and integration of long and short reads to create a robust catalog of kidney compartment-specific isoforms. PMID:35468141
Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer's Disease Patients. PMID:35456941
m5CRegpred: Epitranscriptome Target Prediction of 5-Methylcytosine (m5C) Regulators Based on Sequencing Features. PMID:35456483
Tandem Exon Duplications Expanding the Alternative Splicing Repertoire. PMID:35441045
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism. PMID:35411077
A joint NCBI and EMBL-EBI transcript set for clinical genomics and research. PMID:35388217
Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians. PMID:35313924
Sequencing of individual barcoded cDNAs using Pacific Biosciences and Oxford Nanopore Technologies reveals platform-specific error patterns. PMID:35301264
RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. PMID:35253846
Will Cannabigerol Trigger Neuroregeneration after a Spinal Cord Injury? An In Vitro Answer from NSC-34 Scratch-Injured Cells Transcriptome. PMID:35215230
Single molecule, long-read Apoer2 sequencing identifies conserved and species-specific splicing patterns. PMID:35192893
Understanding the Critical Role of Glycolysis-Related lncRNAs in Lung Adenocarcinoma Based on Three Molecular Subtypes. PMID:35178454
Mouse genomic and cellular annotations. PMID:35124726
ImReLnc: Identifying Immune-Related LncRNA Characteristics in Human Cancers Based on Heuristic Correlation Optimization. PMID:35082835
Missing lnc(RNAs) in Alzheimer's Disease? PMID:35052379
MGcount: a total RNA-seq quantification tool to address multi-mapping and multi-overlapping alignments ambiguity in non-coding transcripts. PMID:35030988
Reciprocal modulation of long noncoding RNA EMS and p53 regulates tumorigenesis. PMID:35022235
Distinct transcription kinetics of pluripotent cell states. PMID:35020268
Identification of Novel Micropeptides Derived from Hepatocellular Carcinoma-Specific Long Noncoding RNA. PMID:35008483
Common Features in lncRNA Annotation and Classification: A Survey. PMID:34940758
What is beyond LncRNAs in breast cancer: A special focus on colon cancer-associated Transcript-1 (CCAT-1). PMID:34938928
Characterizing the Copy Number Variation of Non-Coding RNAs Reveals Potential Therapeutic Targets and Prognostic Markers of LUSC. PMID:34925461
De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy. PMID:34922620
RefSeq Functional Elements as experimentally assayed nongenic reference standards and functional interactions in human and mouse. PMID:34876495
Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling. PMID:34872593
Origins and Function of VL30 lncRNA Packaging in Small Extracellular Vesicles: Implications for Cellular Physiology and Pathology. PMID:34829970
Ensembl 2022. PMID:34791404
ReMap 2022: a database of Human, Mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments. PMID:34751401
Functional Roles of Non-coding RNAs in the Interaction Between Host and Influenza A Virus. PMID:34745043
Mouse Genome Informatics (MGI): latest news from MGD and GXD. PMID:34698891
Comprehensive Genomic Characterization Analysis Identifies an Oncogenic Pseudogene RP11-3543B.1 in Human Gastric Cancer. PMID:34660601
Translational Applications of Linear and Circular Long Noncoding RNAs in Endometriosis. PMID:34638965
Impact of human gene annotations on RNA-seq differential expression analysis. PMID:34625021
Automatic Prediction and Annotation: There Are Strong Biases for Multigenic Families. PMID:34603370
Performance Evaluation of SpliceAI for the Prediction of Splicing of NF1 Variants. PMID:34573290
COVID19db: a comprehensive database platform to discover potential drugs and targets of COVID-19 at whole transcriptomic scale. PMID:34554255
Altered DNA Methylation Profiles in SF3B1 Mutated CLL Patients. PMID:34502260
The value of primary transcripts to the clinical and non-clinical genomics community: Survey results and roadmap for improvements. PMID:34435752
Cost-Effective Mapping of Genetic Interactions in Mammalian Cells. PMID:34434222
The Evolution of G-quadruplex Structure in mRNA Untranslated Region. PMID:34366661
Role of Virus-Induced Host Cell Epigenetic Changes in Cancer. PMID:34361112
From Junk to Function: LncRNAs in CNS Health and Disease. PMID:34349622
PLEKHA8P1 Promotes Tumor Progression and Indicates Poor Prognosis of Liver Cancer. PMID:34299245
Extending the Horizon of Homology Detection with Coevolution-based Structure Prediction. PMID:34139218
Genome-wide analysis of primary microRNA expression using H3K36me3 ChIP-seq data. PMID:33995896
The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis. PMID:33435206

Tags:

Tags
More detailed information about this field from each metasource.

biotype
metasource: re3data.org
version: re3data.org: GENCODE; editing status 2022-04-29; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R38055 last accessed: 2022-11-04

chromosomes
metasource: re3data.org
version: re3data.org: GENCODE; editing status 2022-04-29; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R38055 last accessed: 2022-11-04

genes
metasource: re3data.org
version: re3data.org: GENCODE; editing status 2022-04-29; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R38055 last accessed: 2022-11-04

human
metasource: re3data.org
version: re3data.org: GENCODE; editing status 2022-04-29; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R38055 last accessed: 2022-11-04

mouse
metasource: re3data.org
version: re3data.org: GENCODE; editing status 2022-04-29; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R38055 last accessed: 2022-11-04

protein
metasource: re3data.org
version: re3data.org: GENCODE; editing status 2022-04-29; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R38055 last accessed: 2022-11-04

workflows
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:07.713103

functional, regulatory and non-coding rna
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:07.713103

genomics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:07.713103

biotype chromosomes gene human mouse protein workflows functional, regulatory and non-coding rna genomics

More to explore:

1/20

Previous Next

Need help integrating and/or managing biomedical data?

GENCODE

Webpage:

Licence:

More to explore:

1/20

ENCODE Project

Encyclopedia of DNA Elements at UCSC

modENCODE

Mouse Genome Database - a Mouse Genome Informatics (MGI) Resource

The Consensus CDS

UCSC Genome Browser database

Ensembl

International Mouse Phenotyping Consortium

Kyoto Encyclopedia of Genes and Genomes

Human Protein Atlas

RSSsite

InterFil

Gene Ontology Annotation Database

Gene Ontology

International HapMap Project

ORFDB

SAHG

GenomeTraFaC

Deciphering the Mechanisms of Developmental Disorders

Human Reference Protein Interactome Mapping Project