Atlas of Cancer Signalling Network

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Atlas of Cancer Signalling Network

metasource: Fairsharing.org
version: None

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ACSN

metasource: Fairsharing.org
version: None

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Other names: ACSN

ACSN is a web-based multi-scale resource of biological maps depicting molecular processes in cancer cell and tumor microenvironment. The Atlas represents interconnected cancer-related signalling and metabolic network maps. Molecular mechanisms are depicted on the maps at the level of biochemical interactions, forming a large seamless network. The Atlas is a "geographic-like" interactive "world map" of molecular interactions leading the hallmarks of cancer as described by Hanahan and Weinberg.

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Publications

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Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps
PMID: 26192618

metasource: Fairsharing.org
version: None

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• Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps PubMed citations: 59.

  59 articles citing: Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps

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  Discrete modeling for integration and analysis of large-scale signaling networks. PMID:35696426

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  Innovations in Genomics and Big Data Analytics for Personalized Medicine and Health Care: A Review. PMID:35563034

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  Computational Models for Clinical Applications in Personalized Medicine-Guidelines and Recommendations for Data Integration and Model Validation. PMID:35207655

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  Patient-specific Boolean models of signalling networks guide personalised treatments. PMID:35164900

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  Humans and machines in biomedical knowledge curation: hypertrophic cardiomyopathy molecular mechanisms' representation. PMID:34600580

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  Protein-gene Expression Nexus: Comprehensive characterization of human cancer cell lines with proteogenomic analysis. PMID:34504668

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  A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization. PMID:34040048

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  A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation. PMID:33975535

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  Reusability and composability in process description maps: RAS-RAF-MEK-ERK signalling. PMID:33834185

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  Histamine, Metabolic Remodelling and Angiogenesis: A Systems Level Approach. PMID:33799732

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  SBGN Bricks Ontology as a tool to describe recurring concepts in molecular networks. PMID:33758926

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  Integrated intra- and intercellular signaling knowledge for multicellular omics analysis. PMID:33749993

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  Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach. PMID:33659043

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  LimeMap: a comprehensive map of lipid mediator metabolic pathways. PMID:33504811

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  The status of causality in biological databases: data resources and data retrieval possibilities to support logical modeling. PMID:33378765

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  Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer: Deciphering Key Mechanisms Using Computational Systems Biology Approaches. PMID:33374292

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  Gene- and pathway-level analyses of iCOGS variants highlight novel signaling pathways underlying familial breast cancer susceptibility. PMID:33368296

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  A Middle-Out Modeling Strategy to Extend a Colon Cancer Logical Model Improves Drug Synergy Predictions in Epithelial-Derived Cancer Cell Lines. PMID:33195403

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  Computational Verification of Large Logical Models-Application to the Prediction of T Cell Response to Checkpoint Inhibitors. PMID:33101049

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  A systematic study of critical miRNAs on cells proliferation and apoptosis by the shortest path. PMID:32894041

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  An Integrated Genomic Strategy to Identify CHRNB4 as a Diagnostic/Prognostic Biomarker for Targeted Therapy in Head and Neck Cancer. PMID:32455963

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  Automated inference of Boolean models from molecular interaction maps using CaSQ. PMID:32403123

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  Comprehensive Map of the Regulated Cell Death Signaling Network: A Powerful Analytical Tool for Studying Diseases. PMID:32316560

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  RA-map: building a state-of-the-art interactive knowledge base for rheumatoid arthritis. PMID:32311035

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  A Computational Approach for Mapping Heme Biology in the Context of Hemolytic Disorders. PMID:32211383

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  Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines. PMID:32119655

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  A scalable method for parameter-free simulation and validation of mechanistic cellular signal transduction network models. PMID:31934349

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  Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines. PMID:31733513

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  pathDIP 4: an extended pathway annotations and enrichment analysis resource for human, model organisms and domesticated species. PMID:31733064

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  Acquisition of Invasiveness by Breast Adenocarcinoma Cells Engages Established Hallmarks and Novel Regulatory Mechanisms. PMID:31659104

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  A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures. PMID:31641119

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  CancerGeneNet: linking driver genes to cancer hallmarks. PMID:31598703

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  MINERVA API and plugins: opening molecular network analysis and visualization to the community. PMID:31074494

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  The 2017 Network Tools and Applications in Biology (NETTAB) workshop: aims, topics and outcomes. PMID:30999855

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  Metabolic and signalling network maps integration: application to cross-talk studies and omics data analysis in cancer. PMID:30999838

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  Computational Approaches in Theranostics: Mining and Predicting Cancer Data. PMID:30871264

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  The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. PMID:30371894

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  Clustering approaches for visual knowledge exploration in molecular interaction networks. PMID:30157777

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  Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms. PMID:29872544

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  A comparison of mechanistic signaling pathway activity analysis methods. PMID:29868818

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  A computational framework for complex disease stratification from multiple large-scale datasets. PMID:29843806

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  Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy. PMID:29760221

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  Signalling maps in cancer research: construction and data analysis. PMID:29688383

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  Community-driven roadmap for integrated disease maps. PMID:29688273

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  Navigating the disease landscape: knowledge representations for contextualizing molecular signatures. PMID:29684165

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  A graphical and computational modeling platform for biological pathways. PMID:29543794

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  Inferring hidden causal relations between pathway members using reduced Google matrix of directed biological networks. PMID:29370181

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  Classification of gene signatures for their information value and functional redundancy. PMID:29263798

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  MINERVA-a platform for visualization and curation of molecular interaction networks. PMID:28725475

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  Logic Modeling in Quantitative Systems Pharmacology. PMID:28681552

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  Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation. PMID:28499365

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  NaviCom: a web application to create interactive molecular network portraits using multi-level omics data. PMID:28415074

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  STON: exploring biological pathways using the SBGN standard and graph databases. PMID:27919219

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  Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors. PMID:27559053

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  Human Prostate Cancer Hallmarks Map. PMID:27476486

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  Integration and Visualization of Translational Medicine Data for Better Understanding of Human Diseases. PMID:27441714

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  Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine. PMID:27191992

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  ROMA: Representation and Quantification of Module Activity from Target Expression Data. PMID:26925094

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  DeDaL: Cytoscape 3 app for producing and morphing data-driven and structure-driven network layouts. PMID:26271256

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cancer

metasource: Fairsharing.org
version: None

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cell cycle

metasource: Fairsharing.org
version: None

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cell morphology

metasource: Fairsharing.org
version: None

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cellular assay

metasource: Fairsharing.org
version: None

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signaling

metasource: Fairsharing.org
version: None

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tumor

metasource: Fairsharing.org
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cancer cell cycle cell morphology cellular assay signaling tumor