R3K34M last accessed: 2022-11-04

Other names: TCGA, Cancer GenomeAtlas Data Portal, Cancer Genome Atlas Data Portal, TCGA Data Portal

The Cancer Genome Atlas (TCGA) is a comprehensive, collaborative effort led by the National Institutes of Health (NIH) to map the genomic changes associated with specific types of tumors to improve the prevention, diagnosis and treatment of cancer. Its mission is to accelerate the understanding of the molecular basis of cancer through the application of genome analysis and characterization technologies.

Webpage:

http://cancergenome.nih.gov/

Licence:

Name: The Cancer Genome Atlas data policies and guidelines
URL: https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga/history/policies

Publications:

Publications
More detailed information about this field from each metasource.

The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge
PMID: 25691825
metasource: Fairsharing.org
version: FAIRsharing.org: TCGA; The Cancer Genome Atlas; DOI: https://doi.org/10.25504/FAIRsharing.m8wewa; Last edited: Jan. 3, 2020, 3:17 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

Cancer genomics: from discovery science to personalized medicine
PMID: 21383744
metasource: Fairsharing.org
version: FAIRsharing.org: TCGA; The Cancer Genome Atlas; DOI: https://doi.org/10.25504/FAIRsharing.m8wewa; Last edited: Jan. 3, 2020, 3:17 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

Making sense of cancer genomic data
PMID: 21406553
metasource: Fairsharing.org
version: FAIRsharing.org: TCGA; The Cancer Genome Atlas; DOI: https://doi.org/10.25504/FAIRsharing.m8wewa; Last edited: Jan. 3, 2020, 3:17 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

The future of cancer genomics
PMID: 25654590
metasource: Fairsharing.org
version: FAIRsharing.org: TCGA; The Cancer Genome Atlas; DOI: https://doi.org/10.25504/FAIRsharing.m8wewa; Last edited: Jan. 3, 2020, 3:17 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge PubMed citations: 1231.

1231 articles citing: The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge

Multimodal Dimension Reduction and Subtype Classification of Head and Neck Squamous Cell Tumors. PMID:35912202
Identifying the Antitumor Effects of Curcumin on Lung Adenocarcinoma Using Comprehensive Bioinformatics Analysis. PMID:35910781
RAB39B as a Chemosensitivity-Related Biomarker for Diffuse Large B-Cell Lymphoma. PMID:35910358
Identification of immune-related and autophagy-related genes for the prediction of survival in bladder cancer. PMID:35909123
PO2RDF: representation of real-world data for precision oncology using resource description framework. PMID:35907849
Characterizing the extracellular matrix transcriptome of cervical, endometrial, and uterine cancers. PMID:35898192
Evaluating the utility of an immune checkpoint-related lncRNA signature for identifying the prognosis and immunotherapy response of lung adenocarcinoma. PMID:35896612
New Drug Development and Clinical Trial Design by Applying Genomic Information Management. PMID:35893795
Pan-Cancer Analysis Reveals the Prognostic Potential of the THAP9/THAP9-AS1 Sense-Antisense Gene Pair in Human Cancers. PMID:35893234
Multi-Level Biological Network Analysis and Drug Repurposing Based on Leukocyte Transcriptomics in Severe COVID-19: In Silico Systems Biology to Precision Medicine. PMID:35887528
Conserved Control Path in Multilayer Networks. PMID:35885201
EGFAFS: A Novel Feature Selection Algorithm Based on Explosion Gravitation Field Algorithm. PMID:35885095
An Integrated Bioinformatics Analysis towards the Identification of Diagnostic, Prognostic, and Predictive Key Biomarkers for Urinary Bladder Cancer. PMID:35884419
Deciphering Prognostic Value of TTN and Its Correlation With Immune Infiltration in Lung Adenocarcinoma. PMID:35875159
Arecoline Is Associated With Inhibition of Cuproptosis and Proliferation of Cancer-Associated Fibroblasts in Oral Squamous Cell Carcinoma: A Potential Mechanism for Tumor Metastasis. PMID:35875097
Molecular Subtyping Based on Cuproptosis-Related Genes and Characterization of Tumor Microenvironment Infiltration in Kidney Renal Clear Cell Carcinoma. PMID:35875087
Chromatin Separation Regulators Predict the Prognosis and Immune Microenvironment Estimation in Lung Adenocarcinoma. PMID:35873497
Advances and Trends in Omics Technology Development. PMID:35860739
GRAMD1A Is a Biomarker of Kidney Renal Clear Cell Carcinoma and Is Associated with Immune Infiltration in the Tumour Microenvironment. PMID:35860689
Expression characteristics of long non-coding RNA in colon adenocarcinoma and its potential value for judging the survival and prognosis of patients: bioinformatics analysis based on The Cancer Genome Atlas database. PMID:35837189
Overexpressed SNRPB/D1/D3/E/F/G correlate with poor survival and immune infiltration in hepatocellular carcinoma. PMID:35836882
A systematic pan-cancer analysis identifies RIOK3 as an immunological and prognostic biomarker. PMID:35836879
DriverRWH: discovering cancer driver genes by random walk on a gene mutation hypergraph. PMID:35831792
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery. PMID:35831314
Identifying KRT20 as a Potential Key Gene in Lymphatic Metastasis of Head and Neck Squamous Cell Carcinoma. PMID:35815926
Differential Private Deep Learning Models for Analyzing Breast Cancer Omics Data. PMID:35814415
Contrast-Enhanced Computed Tomography-Based Radiogenomics Analysis for Predicting Prognosis in Gastric Cancer. PMID:35814414
Potential Diagnostic and Prognostic Values of CBX8 Expression in Liver Hepatocellular Carcinoma, Kidney Renal Clear Cell Carcinoma, and Ovarian Cancer: A Study Based on TCGA Data Mining. PMID:35813444
Long non-coding RNA lncHUPC1 induced by FOXA1 promotes tumor progression by inhibiting apoptosis via miR-133b/SDCCAG3 in prostate cancer. PMID:35812058
HistoML, a markup language for representation and exchange of histopathological features in pathology images. PMID:35803960
Identification of Two Subtypes and Prognostic Characteristics of Lung Adenocarcinoma Based on Pentose Phosphate Metabolic Pathway-Related Long Non-coding RNAs. PMID:35801241
Potential Application of Pyroptosis in Kidney Renal Clear Cell Carcinoma Immunotherapy and Targeted Therapy. PMID:35795559
A Necroptosis-Related lncRNA Signature Predicts Prognosis and Indicates the Immune Microenvironment in Soft Tissue Sarcomas. PMID:35795204
A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets. PMID:35791393
Recognition of Key Genes in Human Anaplastic Thyroid Cancer via the Weighing Gene Coexpression Network. PMID:35782055
Precision Medicine: An Optimal Approach to Patient Care in Renal Cell Carcinoma. PMID:35775004
Znet: Deep Learning Approach for 2D MRI Brain Tumor Segmentation. PMID:35774412
INK4 cyclin-dependent kinase inhibitors as potential prognostic biomarkers and therapeutic targets in hepatocellular carcinoma. PMID:35771229
Identification and Validation of lncRNA-AC087588.2 in Lung Adenocarcinoma: A Novel Prognostic and Diagnostic Indicator. PMID:35769906
Comprehensive analysis of CXCR family members in lung adenocarcinoma with prognostic values. PMID:35768814
Network-based machine learning approach to predict immunotherapy response in cancer patients. PMID:35764641
Prognostic Implication and Immunological Role of PSMD2 in Lung Adenocarcinoma. PMID:35754829
[The Expression of RTN1 in Lung Adenocarcinoma and Its Effect on Immune Microenvironment]. PMID:35747917
MDMF: Predicting miRNA-Disease Association Based on Matrix Factorization with Disease Similarity Constraint. PMID:35743670
Machine Learning of Raman Spectroscopy Data for Classifying Cancers: A Review of the Recent Literature. PMID:35741300
Identifying the Potential Roles of PBX4 in Human Cancers Based on Integrative Analysis. PMID:35740947
Digital Analysis of Smart Registration Methods for Magnetic Resonance Images in Public Healthcare. PMID:35734757
Promising prognostic value of Transglutaminase type 2 and its correlation with tumor-infiltrating immune cells in skin cutaneous melanoma. PMID:35725560
Potential of Mitochondrial Ribosomal Genes as Cancer Biomarkers Demonstrated by Bioinformatics Results. PMID:35719986
Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer. PMID:35719950
Towards 'end-to-end' analysis and understanding of biological timecourse data. PMID:35713413
Comprehensive Characterization of Necroptosis-Related lncRNAs in Bladder Cancer Identifies a Novel Signature for Prognosis Prediction. PMID:35711565
Copula diagnostics for asymmetries and conditional dependence. PMID:35707577
The 1q21.3 region driver gene EFNA3 promotes disease progression via inhibition of lung adenocarcinoma cell apoptosis. PMID:35706812
An integrative pan-cancer analysis of molecular characteristics and oncogenic role of mitochondrial creatine kinase 1A (CKMT1A) in human tumors. PMID:35705641
Comprehensive analysis of KCTD family genes associated with hypoxic microenvironment and immune infiltration in lung adenocarcinoma. PMID:35705627
Immunological role and prognostic potential of CLEC10A in pan-cancer. PMID:35702069
Bioinformatic Analysis Identifying PSMB 1/2/3/4/6/8/9/10 as Prognostic Indicators in Clear Cell Renal Cell Carcinoma. PMID:35693739
Comprehensive Analysis of Prognostic Value and Immune Infiltration of NLRC4 and CASP1 in Colorectal Cancer. PMID:35692355
A Genomic Information Management System for Maintaining Healthy Genomic States and Application of Genomic Big Data in Clinical Research. PMID:35682641
GNOSIS: an R Shiny app supporting cancer genomics survival analysis with cBioPortal. PMID:35677713
Characterization of 7-Methylguanosine Identified Biochemical Recurrence and Tumor Immune Microenvironment in Prostate Cancer. PMID:35677157
Distinctive functional regime of endogenous lncRNAs in dark regions of human genome. PMID:35664234
A novel integrative computational framework for breast cancer radiogenomic biomarker discovery. PMID:35664228
Survival-Associated Metabolic Genes and Risk Scoring System in HER2-Positive Breast Cancer. PMID:35663326
Long Non-Coding RNA AL139385.1 as a Novel Prognostic Biomarker in Lung Adenocarcinoma. PMID:35651789
Over-Expression of Long Non-Coding RNA-AC099850.3 Correlates With Tumor Progression and Poor Prognosis in Lung Adenocarcinoma. PMID:35646670
An Integrated Systematic Analysis and the Clinical Significance of Hepcidin in Common Malignancies of the Male Genitourinary System. PMID:35646093
Obesity-Associated Differentially Methylated Regions in Colon Cancer. PMID:35629083
Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease. PMID:35627149
Effects of Multi-Omics Characteristics on Identification of Driver Genes Using Machine Learning Algorithms. PMID:35627101
Association of a Novel DOCK2 Mutation-Related Gene Signature With Immune in Hepatocellular Carcinoma. PMID:35620462
Identification of gene signatures for COAD using feature selection and Bayesian network approaches. PMID:35610288
Human-centered explainability for life sciences, healthcare, and medical informatics. PMID:35607616
A N7-Methylguanine-Related Gene Signature Applicable for the Prognosis and Microenvironment of Prostate Cancer. PMID:35602299
DeepLION: Deep Multi-Instance Learning Improves the Prediction of Cancer-Associated T Cell Receptors for Accurate Cancer Detection. PMID:35601486
A Four-Gene Prognostic Signature Based on the TEAD4 Differential Expression Predicts Overall Survival and Immune Microenvironment Estimation in Lung Adenocarcinoma. PMID:35600867
Role of CDH23 as a prognostic biomarker and its relationship with immune infiltration in acute myeloid leukemia. PMID:35597916
Multi-Omics Approaches Identify Necroptosis‑Related Prognostic Signature and Associated Regulatory Axis in Cervical Cancer. PMID:35592536
Identification and Verification of m7G Modification Patterns and Characterization of Tumor Microenvironment Infiltration via Multi-Omics Analysis in Clear Cell Renal Cell Carcinoma. PMID:35592316
OAS3 is a Co-Immune Biomarker Associated With Tumour Microenvironment, Disease Staging, Prognosis, and Treatment Response in Multiple Cancer Types. PMID:35592250
Tumor Suppressive Role of MUC6 in Wilms Tumor via Autophagy-Dependent β-Catenin Degradation. PMID:35574418
Gene Expression Profiling of Glioblastoma to Recognize Potential Biomarker Candidates. PMID:35571016
High expression of C10orf91 and LINC01224 in hepatocellular carcinoma and poor prognosis. PMID:35559369
A Pan-Cancer Analysis of the Oncogenic Role of WD Repeat Domain 74 in Multiple Tumors. PMID:35559034
Identification of potential prognostic biomarkers for hepatocellular carcinoma. PMID:35557563
Identification of the key genes controlling stomach adenocarcinoma stem cell characteristics via an analysis of stemness indices. PMID:35557559
Digital Pathology and Artificial Intelligence Applications in Pathology. PMID:35545826
Mining the prognostic significance and immune infiltration of STAT family members in human breast cancer by bioinformatics analysis. PMID:35531108
LAMP2 as a Biomarker Related to Prognosis and Immune Infiltration in Esophageal Cancer and Other Cancers: A Comprehensive Pan-Cancer Analysis. PMID:35530327
Identification of immune-related biomarkers associated with tumorigenesis and prognosis in skin cutaneous melanoma. PMID:35530289
Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation. PMID:35528975
Potential Key Markers for Predicting the Prognosis of Gastric Adenocarcinoma Based on the Expression of Ferroptosis-Related lncRNA. PMID:35528617
Noncoding RNAs endogenously rule the cancerous regulatory realm while proteins govern the normal. PMID:35521545
Functional deficiency of succinate dehydrogenase promotes tumorigenesis and development of clear cell renal cell carcinoma through weakening of ferroptosis. PMID:35510387
Comprehensive Analysis of Phagocytosis-Related Regulators to Aid Prognostic Prediction and Immunotherapy in Patients with Low-Grade Glioma. PMID:35510040
Differentially Expressed Genes in Nasopharyngeal Carcinoma Tissues and Their Correlation with Recurrence and Metastasis of Nasopharyngeal Carcinoma. PMID:35509856
miRModuleNet: Detecting miRNA-mRNA Regulatory Modules. PMID:35495139
SRSF3 Expression Serves as a Potential Biomarker for Prognostic and Immune Response in Pan-Cancer. PMID:35494088
Development and Validation of TACE Refractoriness-Related Diagnostic and Prognostic Scores and Characterization of Tumor Microenvironment Infiltration in Hepatocellular Carcinoma. PMID:35493518
Overexpression of SSR2 promotes proliferation of liver cancer cells and predicts prognosis of patients with hepatocellular carcinoma. PMID:35481617
A Bioinformatic Analysis: The Overexpression and Prognostic Potential of GPX7 in Lower-Grade Glioma. PMID:35480989
Comprehensive Landscape of Prognostic Significance and Immune Characteristics of Myosins in Squamous Cell Carcinoma of the Head and Neck. PMID:35478939
The identification of liver metastasis- and prognosis-associated genes in pancreatic ductal adenocarcinoma. PMID:35477379
Construction of an algorithm based on oncosis-related LncRNAs comprising the molecular subtypes and a risk assessment model in lung adenocarcinoma. PMID:35476781
Comprehensive analysis of the expression, prognosis, and immune infiltrates for CHDs in human lung cancer. PMID:35467222
Construction of a Two-Gene Immunogenomic-Related Prognostic Signature in Lung Squamous Cell Carcinoma. PMID:35463955
Network Pharmacology-Based Approach Combined with Bioinformatic Analytics to Elucidate the Potential of Curcumol against Hepatocellular Carcinoma. PMID:35456457
De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet. PMID:35439941
Comprehensive Analysis on Prognosis and Immune Infiltration of Lysyl Oxidase Family Members in Pancreatic Adenocarcinoma With Experimental Verification. PMID:35433829
Exploring Histological Similarities Across Cancers From a Deep Learning Perspective. PMID:35433493
lncRNA CDKN2B-AS1 Could Be an Indicator to Identify Prognosis and Status of Immune Microenvironment in Thyroid Cancer. PMID:35432631
Ferroptosis-Related Long Noncoding RNAs as Prognostic Marker for Colon Adenocarcinoma. PMID:35432591
Expression Profiles of HOXC6 Predict the Survival of Glioblastoma Patients and Correlate with Cell Cycle. PMID:35432534
Editorial: Clinical Genome Sequencing: Bioinformatics Challenges and Key Considerations. PMID:35432455
Targeting mutations in cancer. PMID:35426374
Systematic Characterization of the Clinical Relevance of KPNA4 in Pancreatic Ductal Adenocarcinoma. PMID:35425701
Prognostic Implications and Immune Infiltration Characteristics of Chromosomal Instability-Related Dysregulated CeRNA in Lung Adenocarcinoma. PMID:35419410
Bioinformatics Analysis Identified Five Widely Expressed Genes Associated with Prognosis in Sarcoma. PMID:35414751
PTH2R is related to cell proliferation and migration in ovarian cancer: a multi-omics analysis of bioinformatics and experiments. PMID:35410353
Identification and New Indication of Melanin-Concentrating Hormone Receptor 1 (MCHR1) Antagonist Derived from Machine Learning and Transcriptome-Based Drug Repositioning Approaches. PMID:35409167
BRCA1/2 Serves as a Biomarker for Poor Prognosis in Breast Carcinoma. PMID:35409110
A Comparison of Network-Based Methods for Drug Repurposing along with an Application to Human Complex Diseases. PMID:35409062
CCNA2 as an Immunological Biomarker Encompassing Tumor Microenvironment and Therapeutic Response in Multiple Cancer Types. PMID:35401923
Screening and Validation of a Carvacrol-Targeting Viability-Regulating Protein, SLC6A3, in Liver Hepatocellular Carcinoma. PMID:35401884
Comprehensive Analysis of Colorectal Cancer Immunity and Identification of Immune-Related Prognostic Targets. PMID:35401882
Comprehensive Analysis of YTHDF1 Immune Infiltrates and ceRNA in Human Esophageal Carcinoma. PMID:35401696
SLC2A1 is a Diagnostic Biomarker Involved in Immune Infiltration of Colorectal Cancer and Associated With m6A Modification and ceRNA. PMID:35399515
The Valuable Role of ARMC1 in Invasive Breast Cancer as a Novel Biomarker. PMID:35378785
Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non-small cell lung cancer cells via p53-p21 signaling pathway. PMID:35373420
Cleavage Stimulation Factor Subunit 2: Function Across Cancers and Potential Target for Chemotherapeutic Drugs. PMID:35370655
A Novel Deep Learning Method to Predict Lung Cancer Long-Term Survival With Biological Knowledge Incorporated Gene Expression Images and Clinical Data. PMID:35368657
cSurvival: a web resource for biomarker interactions in cancer outcomes and in cell lines. PMID:35368077
Identification of Pathologic and Prognostic Genes in Prostate Cancer Based on Database Mining. PMID:35360870
The High Expression of Minichromosome Maintenance Complex Component 5 Is an Adverse Prognostic Factor in Lung Adenocarcinoma. PMID:35360518
Solid Tumor Opioid Receptor Expression and Oncologic Outcomes: Analysis of the Cancer Genome Atlas and Genotype Tissue Expression Project. PMID:35359418
A Pan-Cancer Bioinformatic Analysis of RAD51 Regarding the Values for Diagnosis, Prognosis, and Therapeutic Prediction. PMID:35359409
SNRPD1/E/F/G Serve as Potential Prognostic Biomarkers in Lung Adenocarcinoma. PMID:35356432
Construction and Validation of Two Hepatocellular Carcinoma-Progression Prognostic Scores Based on Gene Set Variation Analysis. PMID:35356272
Comprehensive Analysis of ANLN in Human Tumors: A Prognostic Biomarker Associated with Cancer Immunity. PMID:35340220
Deciphering Tumour Heterogeneity: From Tissue to Liquid Biopsy. PMID:35326534
Identification of autophagy-related long non-coding RNAs in endometrial cancer via comprehensive bioinformatics analysis. PMID:35321716
CCDC134 as a Prognostic-Related Biomarker in Breast Cancer Correlating With Immune Infiltrates. PMID:35311121
Analysis of Stemness and Prognosis of Subtypes in Breast Cancer Using the Transcriptome Sequencing Data. PMID:35310908
Identification of a Methylation-Regulating Genes Prognostic Signature to Predict the Prognosis and Aid Immunotherapy of Clear Cell Renal Cell Carcinoma. PMID:35309925
A one-dimensional parameter-free model for carcinogenesis in gene expression space. PMID:35306505
A general calculus of fitness landscapes finds genes under selection in cancers. PMID:35301263
Identification of CXCL10 as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma. PMID:35296026
FDA-led consortium studies advance quality control of targeted next generation sequencing assays for precision oncology. PMID:35282311
The expression of HOXC10 is correlated with tumor-infiltrating immune cells in basal-like breast cancer and serves as a prognostic biomarker. PMID:35282072
Elevated SNRPA1, as a Promising Predictor Reflecting Severe Clinical Outcome via Effecting Tumor Immunity for ccRCC, Is Related to Cell Invasion, Metastasis, and Sunitinib Sensitivity. PMID:35281041
Big Data to Knowledge: Application of Machine Learning to Predictive Modeling of Therapeutic Response in Cancer. PMID:35273457
Role of the Circadian Clock "Death-Loop" in the DNA Damage Response Underpinning Cancer Treatment Resistance. PMID:35269502
Comprehensive Analysis of the Prognosis and Drug Sensitivity of Differentiation-Related lncRNAs in Papillary Thyroid Cancer. PMID:35267662
LINC01094 Predicts Poor Prognosis in Patients With Gastric Cancer and is Correlated With EMT and Macrophage Infiltration. PMID:35254147
MLLT11-TRIL complex promotes the progression of endometrial cancer through PI3K/AKT/mTOR signaling pathway. PMID:35253622
Identification and Comprehensive Analysis of FREM2 Mutation as a Potential Prognostic Biomarker in Colorectal Cancer. PMID:35252356
A Pan-Cancer Analysis of the Oncogenic Role of Cell Division Cycle-Associated Protein 4 (CDCA4) in Human Tumors. PMID:35251007
Fatty Acid Metabolic Signaling Pathway Alternation Predict Prognosis of Immune Checkpoint Inhibitors in Glioblastoma. PMID:35251000
Expression Profile and Prognostic Values of CDH Family Members in Lung Adenocarcinoma. PMID:35242247
Identification of novel prostate cancer genes in patients stratified by Gleason classification: Role of antitumoral genes. PMID:35234293
Pyroptosis-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with UCEC. PMID:35228898
Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis. PMID:35227296
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway. PMID:35222724
Fatty Acid Metabolism in Ovarian Cancer: Therapeutic Implications. PMID:35216285
Stage-differentiated ensemble modeling of DNA methylation landscapes uncovers salient biomarkers and prognostic signatures in colorectal cancer progression. PMID:35202405
FAM65A as a novel prognostic biomarker in human tumors reveal by a pan-cancer analysis. PMID:35201499
Cloud-based archived metabolomics data: A resource for in-source fragmentation/annotation, meta-analysis and systems biology. PMID:35190800
Targets and Potential Mechanism of Scutellaria baicalensis in Treatment of Primary Hepatocellular Carcinoma Based on Bioinformatics Analysis. PMID:35190740
Serum Exosomal lncRNA AC007099.1 Regulates the Expression of Neuropeptide-Related FAP, as a Potential Biomarker for Hepatocarcinogenesis. PMID:35186170
DecOT: Bulk Deconvolution With Optimal Transport Loss Using a Single-Cell Reference. PMID:35186040
Comprehensive analysis of the expression and significance of CXCLs in human diffuse large B-cell lymphoma. PMID:35181719
Novel insight into pancreatic adenocarcinoma pathogenesis using liquid association analysis. PMID:35180880
Validating RRP12 Expression and Its Prognostic Significance in HCC Based on Data Mining and Bioinformatics Methods. PMID:35178347
Comprehensive pan-cancer analysis on CBX3 as a prognostic and immunological biomarker. PMID:35172803
Theranostic Interpolation of Genomic Instability in Breast Cancer. PMID:35163783
How to Slow down the Ticking Clock: Age-Associated Epigenetic Alterations and Related Interventions to Extend Life Span. PMID:35159278
Data Integration Challenges for Machine Learning in Precision Medicine. PMID:35145977
Immune Infiltration of CD8+ T Cells in Patients With Diabetic Pancreatic Cancer Reduces the Malignancy of Cancer Tissues: An In Silico Study. PMID:35145483
Somatic mutational profiles and germline polygenic risk scores in human cancer. PMID:35144655
Comparative analysis of molecular signatures reveals a hybrid approach in breast cancer: Combining the Nottingham Prognostic Index with gene expressions into a hybrid signature. PMID:35143511
CPNE1 is a potential prognostic biomarker, associated with immune infiltrates and promotes progression of hepatocellular carcinoma. PMID:35139863
Immune Checkpoint Gene Expression Profiling Identifies Programmed Cell Death Ligand-1 Centered Immunologic Subtypes of Oral and Squamous Cell Carcinoma With Favorable Survival. PMID:35127742
Federated learning and differential privacy for medical image analysis. PMID:35121774
Identification of tumor microenvironment-related genes in lower-grade gliomas by mining TCGA database. PMID:35117823
Gastric cancer risk-scoring system based on analysis of a competing endogenous RNA network. PMID:35117756
Construction and integrated analysis of a lncRNA-associated competing endogenous RNA network reveal functional lncRNAs in pancreatic cancer. PMID:35117727
Cyclophilin B overexpression predicts a poor prognosis and activates metastatic pathways in colon cancer. PMID:35117721
Higher T cell immunoglobulin mucin-3 (Tim-3) expression in cervical cancer is associated with a satisfactory prognosis. PMID:35117637
Candidate genes for predicting the survival of patients with gastric cancer: a study based on The Cancer Genome Atlas (TCGA) database. PMID:35117619
MAFA-AS1, a long non-coding RNA, predicts for poor survival of hepatocellular carcinoma. PMID:35117604
The expression and prognostic value of RNA binding proteins in clear cell renal cell carcinoma. PMID:35117342
Screening of differential expressed genes from gene chip and sequencing data and evaluate its prognostic values in males with digestive system neoplasms. PMID:35116986
Survival-based bioinformatics analysis to identify hub genes and key pathways in non-small cell lung cancer. PMID:35116861
Pan-cancer analysis of CXCR4 carcinogenesis in human tumors. PMID:35116714
An investigation to identify tumor microenvironment-related genes of prognostic value in lung squamous cell carcinoma based on The Cancer Genome Atlas. PMID:35116510
A comprehensive analysis of the expression and regulation network of lymphocyte-specific protein tyrosine kinase in breast cancer. PMID:35116477
ANKDD1A may serve as a critical gene in the immune microenvironment of breast cancer. PMID:35116461
Identification and validation of tumor microenvironment-related prognostic biomarkers in breast cancer. PMID:35116294
Liver-specific LINC01146, a promising prognostic indicator, inhibits the malignant phenotype of hepatocellular carcinoma cells both in vitro and in vivo. PMID:35101062
Prognostic Signatures and Therapeutic Value Based on the Notch Pathway in Renal Clear Cell Carcinoma. PMID:35096263
Identification of Novel Subtypes in Lung Adenocarcinoma: Evidence from Gene Set Variation Analysis in Tumor and Adjacent Nontumor Samples. PMID:35096200
The oncogenic role of treacle ribosome biogenesis factor 1 (TCOF1) in human tumors: a pan-cancer analysis. PMID:35093935
CKMT1A is a novel potential prognostic biomarker in patients with endometrial cancer. PMID:35077462
ROSIE: RObust Sparse ensemble for outlIEr detection and gene selection in cancer omics data. PMID:35072570
Gene signature to predict prognostic survival of hepatocellular carcinoma. PMID:35071775
Prognostic prediction and gene regulation network of EIF2S2 in hepatocellular carcinoma based on data mining. PMID:35070430
Evaluation of the Prognostic Value of Long Noncoding RNAs in Lung Squamous Cell Carcinoma. PMID:35069738
Pan-Cancer Analysis Revealed SRSF9 as a New Biomarker for Prognosis and Immunotherapy. PMID:35069733
Landscape Analysis of Matrix Metalloproteinases Unveils Key Prognostic Markers for Patients With Breast Cancer. PMID:35069702
CpG Island Methylator Phenotype-A Hope for the Future or a Road to Nowhere? PMID:35055016
Molecular Mechanisms of lncRNAs in the Dependent Regulation of Cancer and Their Potential Therapeutic Use. PMID:35054945
Noncoding RNAs and Deep Learning Neural Network Discriminate Multi-Cancer Types. PMID:35053515
The initial expression alterations occurring to transcription factors during the formation of breast cancer: Evidence from bioinformatics. PMID:35037412
The functions and prognostic value of Krüppel-like factors in breast cancer. PMID:35033064
Circular RNA hsa_circ_0032683 inhibits the progression of hepatocellular carcinoma by sponging microRNA-338-5p. PMID:35030979
A Novel Angiogenesis-Related Prognostic Signature Associated with the Hepatocellular Carcinoma Immune Microenvironment and Survival Outcome. PMID:35027841
Characterization of an Autophagy-Immune Related Genes Score Signature and Prognostic Model and its Correlation with Immune Response for Bladder Cancer. PMID:35023971
MiR-423-5p prevents MALAT1-mediated proliferation and metastasis in prostate cancer. PMID:35016717
LncRNA TP73-AS1 promotes nasopharyngeal carcinoma progression through targeting miR-342-3p and M2 polarization via exosomes. PMID:35012518
Potential biomarkers and signaling pathways associated with the pathogenesis of primary salivary gland carcinoma: a bioinformatics study. PMID:35012286
Unveiling a Ghost Proteome in the Glioblastoma Non-Coding RNAs. PMID:35004666
ANXA9 as a novel prognostic biomarker associated with immune infiltrates in gastric cancer. PMID:35003923
Construction and Clinical Translation of Causal Pan-Cancer Gene Score Across Cancer Types. PMID:35003220
Exome sequencing of glioblastoma-derived cancer stem cells reveals rare clinically relevant frameshift deletion in MLLT1 gene. PMID:34996478
Single-Cell Sequencing of Hepatocellular Carcinoma Reveals Cell Interactions and Cell Heterogeneity in the Microenvironment. PMID:34992435
M2PP: a novel computational model for predicting drug-targeted pathogenic proteins. PMID:34983358
Unbox the black-box for the medical explainable AI via multi-modal and multi-centre data fusion: A mini-review, two showcases and beyond. PMID:34980946
Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer. PMID:34980144
KRAS Mutations in Squamous Cell Carcinomas of the Lung. PMID:34976827
Application of Sparse Representation in Bioinformatics. PMID:34976030
High Expression of CEMIP Correlates Poor Prognosis and the Tumur Microenvironment in Breast Cancer as a Promisingly Prognostic Biomarker. PMID:34966410
Identification of MCM4 as a Prognostic Marker of Hepatocellular Carcinoma. PMID:34961841
Identification of an Autophagy-Related lncRNA Prognostic Signature and Related Tumor Immunity Research in Lung Adenocarcinoma. PMID:34956321
An immune-related lncRNA risk coefficient model to predict the outcomes in clear cell renal cell carcinoma. PMID:34954690
ITGB3BP is a potential biomarker associated with poor prognosis of glioma. PMID:34953037
Synergistic Effects of Different Levels of Genomic Data for the Staging of Lung Adenocarcinoma: An Illustrative Study. PMID:34946821
An integrative pan-cancer analysis reveals the oncogenic role of mutS homolog 6 (MSH6) in human tumors. PMID:34941572
Identification of potential key genes and functional role of CENPF in osteosarcoma using bioinformatics and experimental analysis. PMID:34934449
GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation. PMID:34933446
Metabolic syndrome related gene signature predicts the prognosis of patients with pancreatic ductal carcinoma. A novel link between metabolic dysregulation and pancreatic ductal carcinoma. PMID:34930261
Comprehensive analysis identifies IFI16 as a novel signature associated with overall survival and immune infiltration of skin cutaneous melanoma. PMID:34930258
Comprehensive Analysis of Aldehyde Dehydrogenases (ALDHs) and Its Significant Role in Hepatocellular Carcinoma. PMID:34928471
Single-Nucleotide Polymorphisms Promote Dysregulation Activation by Essential Gene Mediated Bio-Molecular Interaction in Breast Cancer. PMID:34926308
Characterizing the Copy Number Variation of Non-Coding RNAs Reveals Potential Therapeutic Targets and Prognostic Markers of LUSC. PMID:34925461
Prognostic Implications and Immune Infiltration Analysis of ALDOA in Lung Adenocarcinoma. PMID:34925439
Antiviral Responses in Cancer: Boosting Antitumor Immunity Through Activation of Interferon Pathway in the Tumor Microenvironment. PMID:34925363
Promoter methylation-mediated repression of UNC5 receptors and the associated clinical significance in human colorectal cancer. PMID:34922605
C1632 suppresses the migration and proliferation of non-small-cell lung cancer cells involving LIN28 and FGFR1 pathway. PMID:34913237
Exploring Pathway-Based Group Lasso for Cancer Survival Analysis: A Special Case of Multi-Task Learning. PMID:34912376
Identification and Development of Subtypes with Poor Prognosis in Gastric Cancer Based on Both Hypoxia and Immune Cell Infiltration. PMID:34908867
LRMP Associates With Immune Infiltrates and Acts as a Prognostic Biomarker in Lung Adenocarcinoma. PMID:34901148
Development of an Oxidative Phosphorylation-Related and Immune Microenvironment Prognostic Signature in Uterine Corpus Endometrial Carcinoma. PMID:34901000
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. PMID:34900668
MultiCapsNet: A General Framework for Data Integration and Interpretable Classification. PMID:34899854
Excavating novel diagnostic and prognostic long non-coding RNAs (lncRNAs) for head and neck squamous cell carcinoma: an integrated bioinformatics analysis of competing endogenous RNAs (ceRNAs) and gene co-expression networks. PMID:34898376
De novo Prediction of Cell-Drug Sensitivities Using Deep Learning-based Graph Regularized Matrix Factorization. PMID:34890156
Optimised expression and purification of RBP4 and preparation of anti-RBP4 monoclonal antibody. PMID:34889069
Experimental and Meta-Analytic Validation of RNA Sequencing Signatures for Predicting Status of Microsatellite Instability. PMID:34888350
Landscape of the oncogenic role of fatty acid synthase in human tumors. PMID:34879004
TIFAB accelerates MLL-AF9-Induced acute myeloid leukemia through upregulation of HOXA9. PMID:34877491
Gene Co-Expression in Breast Cancer: A Matter of Distance. PMID:34868919
Identification of SOX6 and SOX12 as Prognostic Biomarkers for Clear Cell Renal Cell Carcinoma: A Retrospective Study Based on TCGA Database. PMID:34868396
CD73 Severed as a Potential Prognostic Marker and Promote Lung Cancer Cells Migration via Enhancing EMT Progression. PMID:34868205
Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification. PMID:34859007
Key Markers Involved in the Anticolon Cancer Response of CD8+ T Cells through the Regulation of Cholesterol Metabolism. PMID:34858500
A Transcriptional Signature of IL-2 Expanded Natural Killer Cells Predicts More Favorable Prognosis in Bladder Cancer. PMID:34858395
miRTarBase update 2022: an informative resource for experimentally validated miRNA-target interactions. PMID:34850920
Challenges and opportunities in network-based solutions for biological questions. PMID:34849568
Microenvironment-associated gene HSD11B1 may serve as a prognostic biomarker in clear cell renal cell carcinoma: a study based on TCGA, RT‑qPCR, Western blotting, and immunohistochemistry. PMID:34845968
A Pan-Cancer Analysis of Clinical Prognosis and Immune Infiltration of CKS1B in Human Tumors. PMID:34845438
Identification and Potential Mechanisms of a 7-MicroRNA Signature That Predicts Prognosis in Patients with Lower-Grade Glioma. PMID:34845420
Comprehensive Analysis of CPA4 as a Poor Prognostic Biomarker Correlated with Immune Cells Infiltration in Bladder Cancer. PMID:34827136
In silico Methods for Identification of Potential Therapeutic Targets. PMID:34826045
Are we there yet? A machine learning architecture to predict organotropic metastases. PMID:34819069
Identification of miRNAs and genes for predicting Barrett's esophagus progressing to esophageal adenocarcinoma using miRNA-mRNA integrated analysis. PMID:34818353
The role of complement in the clinical course of hepatocellular carcinoma. PMID:34813686
Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targets. PMID:34804946
Leptin Receptor Overlapping Transcript (LEPROT) Is Associated with the Tumor Microenvironment and a Prognostic Predictor in Pan-Cancer. PMID:34804118
Construction of circRNA-miRNA-mRNA network and identification of novel potential biomarkers for non-small cell lung cancer. PMID:34801043
Extracellular vesicles miR-210 as a potential biomarker for diagnosis and survival prediction of oral squamous cell carcinoma patients. PMID:34800057
Prognostic Value of E2F Transcription Factor Expression in Pancreatic Adenocarcinoma. PMID:34799547
Construction of a single nucleotide variant score-related gene-based prognostic model in hepatocellular carcinoma: analysis of multi-independent databases and validation in vitro. PMID:34794449
Prognostic and immune infiltrates for the Chromobox (CBX) protein family in human pancreatic adenocarcinoma. PMID:34790394
KDM4 Involvement in Breast Cancer and Possible Therapeutic Approaches. PMID:34778065
CTNNB1 Alternation Is a Potential Biomarker for Immunotherapy Prognosis in Patients With Hepatocellular Carcinoma. PMID:34777372
Computational methods for protein localization prediction. PMID:34765098
Approximate distance correlation for selecting highly interrelated genes across datasets. PMID:34752449
Analysis of Genome-Wide Alternative Splicing Profiling and Development of Potential Drugs in Lung Adenocarcinoma. PMID:34737768
A mixture model for signature discovery from sparse mutation data. PMID:34724984
Using Genomic and Transcriptome Analyses to Identify the Role of the Oxidative Stress Pathway in Renal Clear Cell Carcinoma and Its Potential Therapeutic Significance. PMID:34721758
Urine TERT promoter mutations-based tumor DNA detection in patients with bladder cancer: A pilot study. PMID:34712485
Comprehensive Analysis of Hexokinase 2 Immune Infiltrates and m6A Related Genes in Human Esophageal Carcinoma. PMID:34708035
Gene regulatory network inference as relaxed graph matching. PMID:34707916
Identification and validation of an autophagy-related signature for predicting survival in lower-grade glioma. PMID:34696669
Nkx3-1 and Fech genes might be switch genes involved in pituitary non-functioning adenoma invasiveness. PMID:34686726
Microarray profile analysis identifies ETS1 as potential biomarker regulated by miR-23b and modulates TCF4 in gastric cancer. PMID:34686186
Epigenetic DNA Modifications Upregulate SPRY2 in Human Colorectal Cancers. PMID:34685612
Trends in oligomannosylation and α1,2-mannosidase expression in human cancers. PMID:34676051
Study of Clinical Predictive Value and Immune Characterization of SLFN11 in Clear Cell Renal Cell Carcinoma. PMID:34675634
Comprehensive Analysis of Ferroptosis-Related LncRNAs in Breast Cancer Patients Reveals Prognostic Value and Relationship With Tumor Immune Microenvironment. PMID:34671639
Identification of key genes for HNSCC from public databases using bioinformatics analysis. PMID:34663338
The Landscape of the Tumor Microenvironment in Skin Cutaneous Melanoma Reveals a Prognostic and Immunotherapeutically Relevant Gene Signature. PMID:34660598
Analysis of Methylation-driven Genes in Pancreatic Ductal Adenocarcinoma for Predicting Prognosis. PMID:34659542
The Expression Patterns and Prognostic Value of the Proteasome Activator Subunit Gene Family in Gastric Cancer Based on Integrated Analysis. PMID:34650966
Integrative Analysis of Histopathological Images and Genomic Data in Colon Adenocarcinoma. PMID:34646756
CancerSCEM: a database of single-cell expression map across various human cancers. PMID:34643725
A Survey of Autoencoder Algorithms to Pave the Diagnosis of Rare Diseases. PMID:34639231
Low Levels of TRIM28-Interacting KRAB-ZNF Genes Associate with Cancer Stemness and Predict Poor Prognosis of Kidney Renal Clear Cell Carcinoma Patients. PMID:34638319
SomaMutDB: a database of somatic mutations in normal human tissues. PMID:34634815
CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma. PMID:34631884
High Expression of SLC16A1 as a Biomarker to Predict Poor Prognosis of Urological Cancers. PMID:34631536
An Integrative Pan-Cancer Analysis of the Prognostic and Immunological Role of Casein Kinase 2 Alpha Protein 1 (CSNK2A1) in Human Cancers: A Study Based on Bioinformatics and Immunohistochemical Analysis. PMID:34621130
Overexpression of EWSR1 (Ewing sarcoma breakpoint region 1/EWS RNA binding protein 1) predicts poor survival in patients with hepatocellular carcinoma. PMID:34612781
A novel prognostic immunoscore based on The Cancer Genome Atlas to predict overall survival in colorectal cancer patients. PMID:34608935
A seven-gene signature and the C-C motif chemokine receptor family genes are the sarcoma-related immune genes. PMID:34605725
A Computational Framework to Identify Transcriptional and Network Differences between Hepatocellular Carcinoma and Normal Liver Tissue and Their Applications in Repositioning Drugs. PMID:34604388
Identification of Mutation Landscape and Immune Cell Component for Liver Hepatocellular Carcinoma Highlights Potential Therapeutic Targets and Prognostic Markers. PMID:34603396
A Novel TCGA-Validated, MiRNA-Based Signature for Prediction of Breast Cancer Prognosis and Survival. PMID:34589485
B4GALNT2 Gene Promotes Proliferation, and Invasiveness and Migration Abilities of Model Triple Negative Breast Cancer (TNBC) Cells by Interacting With HLA-B Protein. PMID:34589428
Cancer DEIso: An integrative analysis platform for investigating differentially expressed gene-level and isoform-level human cancer markers. PMID:34589189
MMP1 and MMP9 are potential prognostic biomarkers and targets for uveal melanoma. PMID:34587931
Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogene. PMID:34585645
HNRNPC Promotes Proliferation, Metastasis and Predicts Prognosis in Prostate Cancer. PMID:34584453
Shifting Gears in Precision Oncology-Challenges and Opportunities of Integrative Data Analysis. PMID:34572523
Marginal Contribution Feature Importance - an Axiomatic Approach for Explaining Data. PMID:34568830
Integrating Genetic and Transcriptomic Data to Reveal Pathogenesis and Prognostic Markers of Pancreatic Adenocarcinoma. PMID:34567094
Overcoming barriers to data sharing with medical image generation: a comprehensive evaluation. PMID:34561528
HOXD9‑induced SCNN1A upregulation promotes pancreatic cancer cell proliferation, migration and predicts prognosis by regulating epithelial‑mesenchymal transformation. PMID:34558641
Determination of Genetic and Epigenetic Modifications-Related Prognostic Biomarkers of Breast Cancer: Genome High-Throughput Data Analysis. PMID:34557230
SOX10 Knockdown Inhibits Melanoma Cell Proliferation via Notch Signaling Pathway. PMID:34557039
Midkine promotes glioblastoma progression via PI3K-Akt signaling. PMID:34556138
The Immune Landscape of Chinese Head and Neck Adenoid Cystic Carcinoma and Clinical Implication. PMID:34552580
A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers. PMID:34550356
Identification of colorectal cancer associated biomarkers: an integrated analysis of miRNA expression. PMID:34547721
Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy. PMID:34545095
Identification of potential genes related to breast cancer brain metastasis in breast cancer patients. PMID:34541602
Comprehensive Analysis of a Nine-Gene Signature Related to Tumor Microenvironment in Lung Adenocarcinoma. PMID:34540825
A Transcriptional Signature of PDGF-DD Activated Natural Killer Cells Predicts More Favorable Prognosis in Low-Grade Glioma. PMID:34539622
Comprehensive Analysis to Identify Enhancer-Regulated Inflammation-Associated Genes in Lung Adenocarcinoma. PMID:34539188
Comprehensive Analysis of the Expression and Prognosis for E2Fs in Human Clear Cell Renal Cell Carcinoma. PMID:34531966
A cross-study analysis of drug response prediction in cancer cell lines. PMID:34524425
Protein tyrosine phosphatase, receptor type B is a potential biomarker and facilitates cervical cancer metastasis via epithelial-mesenchymal transition. PMID:34516350
A New Survival Model Based on Cholesterol Biosynthesis-Related Genes for Prognostic Prediction in Clear Cell Renal Cell Carcinoma. PMID:34513998
ESPL1 Is a Novel Prognostic Biomarker Associated With the Malignant Features of Glioma. PMID:34512713
Predicting drug sensitivity of cancer cells based on DNA methylation levels. PMID:34506489
A novel long non-coding RNA-based prognostic signature for renal cell carcinoma patients with stage IV and histological grade G4. PMID:34499010
Prioritizing Susceptible Genes for Thyroid Cancer Based on Gene Interaction Network. PMID:34497810
Dysregulation of KIF14 regulates the cell cycle and predicts poor prognosis in cervical cancer: a study based on integrated approaches. PMID:34495250
Transcriptional analysis of the expression, prognostic value and immune infiltration activities of the COMMD protein family in hepatocellular carcinoma. PMID:34493238
Machine Learning Approaches on High Throughput NGS Data to Unveil Mechanisms of Function in Biology and Disease. PMID:34479914
Prognostic Value of an m5C RNA Methylation Regulator-Related Signature for Clear Cell Renal Cell Carcinoma. PMID:34471382
VERTIcal Grid lOgistic regression with Confidence Intervals (VERTIGO-CI). PMID:34457150
Pan-cancer analysis of the oncogenic role of discs large homolog associated protein 5 (DLGAP5) in human tumors. PMID:34454476
The role of deep learning-based survival model in improving survival prediction of patients with glioblastoma. PMID:34453413
A Transcriptomic Analysis of Head and Neck Squamous Cell Carcinomas for Prognostic Indications. PMID:34442426
Predicting Agents That Can Overcome 5-FU Resistance in Colorectal Cancers via Pharmacogenomic Analysis. PMID:34440086
Flexible co-data learning for high-dimensional prediction. PMID:34438466
Robust biomarker discovery for hepatocellular carcinoma from high-throughput data by multiple feature selection methods. PMID:34433487
IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat. PMID:34424450
Low expression of IL6R predicts poor prognosis for lung adenocarcinoma. PMID:34422969
Molecular Subtypes of Oral Squamous Cell Carcinoma Based on Immunosuppression Genes Using a Deep Learning Approach. PMID:34422810
Ovarian cancer: epigenetics, drug resistance, and progression. PMID:34404407
Integrated bioinformatics analysis reveals CDK1 and PLK1 as potential therapeutic targets of lung adenocarcinoma. PMID:34397869
Bioinformatic Analysis of Prognostic and Immune-Related Genes in Pancreatic Cancer. PMID:34394706
A High Epigenetic Risk Score Shapes the Non-Inflamed Tumor Microenvironment in Breast Cancer. PMID:34381812
Prognostic and Immunological Role of Gasdermin E in Pan-Cancer Analysis. PMID:34381728
k-core genes underpin structural features of breast cancer. PMID:34381069
Cloud Computing Enabled Big Multi-Omics Data Analytics. PMID:34376975
Adaptor Protein Complex 1 Sigma 3 Is Highly Expressed in Glioma and Could Enhance Its Progression. PMID:34367317
An Immune-Related Gene-Based Signature as Prognostic Tool in Ovarian Serous Cystadenocarcinoma. PMID:34354370
m6A-Related lncRNA to Develop Prognostic Signature and Predict the Immune Landscape in Bladder Cancer. PMID:34349798
MiREDiBase, a manually curated database of validated and putative editing events in microRNAs. PMID:34349127
SuMO-Fil: Supervised multi-omic filtering prior to performing network analysis. PMID:34343218
Quantification of long non-coding RNAs using qRT-PCR: comparison of different cDNA synthesis methods and RNA stability. PMID:34336028
Prediction of Disease Genes Based on Stage-Specific Gene Regulatory Networks in Breast Cancer. PMID:34335705
Prognosis of Non-small-cell Lung Cancer Patients With Lipid Metabolism Pathway Alternations to Immunotherapy. PMID:34335679
NPM1 Is a Prognostic Biomarker Involved in Immune Infiltration of Lung Adenocarcinoma and Associated With m6A Modification and Glycolysis. PMID:34335635
Large-Scale Transcriptome Analysis Identified a Novel Cancer Driver Genes Signature for Predicting the Prognostic of Patients With Hepatocellular Carcinoma. PMID:34335239
Database mining analysis revealed the role of the putative H+/sugar transporter solute carrier family 45 in skin cutaneous melanoma. PMID:34334114
On the impact of batch effect correction in TCGA isomiR expression data. PMID:34316700
SPONGEdb: a pan-cancer resource for competing endogenous RNA interactions. PMID:34316695
Integrative analysis reveals the prognostic value and functions of splicing factors implicated in hepatocellular carcinoma. PMID:34312475
MUSTARD-a comprehensive resource of mutation-specific therapies in cancer. PMID:34309639
Identification of Arp2/3 Complex Subunits as Prognostic Biomarkers for Hepatocellular Carcinoma. PMID:34307456
The Impact of NOTCH Pathway Alteration on Tumor Microenvironment and Clinical Survival of Immune Checkpoint Inhibitors in NSCLC. PMID:34305884
Translational Utility of Liquid Biopsies in Thyroid Cancer Management. PMID:34298656
MOUSSE: Multi-Omics Using Subject-Specific SignaturEs. PMID:34298641
Web tools to perform long non-coding RNAs analysis in oncology research. PMID:34296748
Fostering reproducibility, reusability, and technology transfer in health informatics. PMID:34296072
Prognostic Values of E2F1/2 Transcriptional Expressions in Chromophobe Renal Cell Carcinoma Patients: Evidence from Bioinformatics Analysis. PMID:34295182
Risk Score Based on Two microRNAs as a Prognostic Marker of Hepatocellular Carcinoma and the Corresponding Competitive Endogenous RNA Network. PMID:34285562
Establishment of a prognostic-related microRNAs risk model for glioma by bioinformatics analysis. PMID:34277822
Long Non-coding RNAs: Mechanisms, Experimental, and Computational Approaches in Identification, Characterization, and Their Biomarker Potential in Cancer. PMID:34276764
A Novel Computational Framework to Predict Disease-Related Copy Number Variations by Integrating Multiple Data Sources. PMID:34267783
The Early Diagnostic and Prognostic Value of BIRC5 in Clear-Cell Renal Cell Carcinoma Based on the Cancer Genome Atlas Data. PMID:34265766
FSTL3 is a Prognostic Biomarker in Gastric Cancer and is Correlated with M2 Macrophage Infiltration. PMID:34262295
The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18. PMID:34262023
A comprehensive analysis of immune infiltration in the tumor microenvironment of osteosarcoma. PMID:34258887
Identification of Biomarkers Related to Immune Cell Infiltration in Hepatocellular Carcinoma Using Gene Co-Expression Network. PMID:34257558
OncoThreads: visualization of large-scale longitudinal cancer molecular data. PMID:34252935
Automatic Pancreatic Ductal Adenocarcinoma Detection in Whole Slide Images Using Deep Convolutional Neural Networks. PMID:34249702
Identification and Comparative Analysis of Long Non-coding RNAs in High- and Low-Fecundity Goat Ovaries During Estrus. PMID:34249080
A DNA methylation profile of long non-coding RNAs can predict OS in prostate cancer. PMID:34238128
Identification of key genes involved in the recurrence of glioblastoma multiforme using weighted gene co-expression network analysis and differential expression analysis. PMID:34238116
The TP53-Related Signature Predicts Immune Cell Infiltration, Therapeutic Response, and Prognosis in Patients With Esophageal Carcinoma. PMID:34234806
Weighted Gene Coexpression Network Analysis to Construct Competitive Endogenous RNA Network in Chromogenic Renal Cell Carcinoma. PMID:34222474
Identification of Early Diagnostic and Prognostic Biomarkers via WGCNA in Stomach Adenocarcinoma. PMID:34221961
Differential expression analysis in ovarian cancer: A functional genomics and systems biology approach. PMID:34220265
A Comprehensive Bioinformatics Analysis of Notch Pathways in Bladder Cancer. PMID:34205690
Identifying Cancer Drivers Using DRIVE: A Feature-Based Machine Learning Model for a Pan-Cancer Assessment of Somatic Missense Mutations. PMID:34205004
Accurate Segmentation of Nuclear Regions with Multi-Organ Histopathology Images Using Artificial Intelligence for Cancer Diagnosis in Personalized Medicine. PMID:34199932
Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer. PMID:34198846
Genomic and Transcriptome Analysis to Identify the Role of the mTOR Pathway in Kidney Renal Clear Cell Carcinoma and Its Potential Therapeutic Significance. PMID:34194607
KRT7 Overexpression is Associated with Poor Prognosis and Immune Cell Infiltration in Patients with Pancreatic Adenocarcinoma. PMID:34188523
m6A RNA methylation regulators were associated with the malignancy and prognosis of ovarian cancer. PMID:34187307
CircRNA_100290 promotes GC cell proliferation and invasion via the miR-29b-3p/ITGA11 axis and is regulated by EIF4A3. PMID:34182990
Analysis of Nuclear Encoded Mitochondrial Gene Networks in Cervical Cancer. PMID:34181336
Competing Endogenous RNA in Colorectal Cancer: An Analysis for Colon, Rectum, and Rectosigmoid Junction. PMID:34178670
Systemic Analysis of the DNA Replication Regulator MCM Complex in Ovarian Cancer and Its Prognostic Value. PMID:34178669
The Correlation Between SPP1 and Immune Escape of EGFR Mutant Lung Adenocarcinoma Was Explored by Bioinformatics Analysis. PMID:34178613
An Overview of the Computational Models Dealing with the Regulatory ceRNA Mechanism and ceRNA Deregulation in Cancer. PMID:34165714
KDELC1 and TRMT1 Serve as Prognosis-Related SARS-CoV-2 Proteins Binding Human mRNAs and Promising Biomarkers in Clear Cell Renal Cell Carcinoma. PMID:34163216
CXCL10 potentiates immune checkpoint blockade therapy in homologous recombination-deficient tumors. PMID:34158843
[Expression of RASGRP2 in Lung Adenocarcinoma and Its Effect on Immune Microenvironment]. PMID:34157800
Upregulation of LIMK1 Is Correlated With Poor Prognosis and Immune Infiltrates in Lung Adenocarcinoma. PMID:34149814
Ten-year outcomes of uveal melanoma based on The Cancer Genome Atlas (TCGA) classification in 1001 cases. PMID:34146040
The m6A-related gene signature for predicting the prognosis of breast cancer. PMID:34141492
LINC02678 as a Novel Prognostic Marker Promotes Aggressive Non-small-cell Lung Cancer. PMID:34124072
Comprehensive Analysis of GLUT1 Immune Infiltrates and ceRNA Network in Human Esophageal Carcinoma. PMID:34123828
Benign vs malignant pancreatic lesions: Molecular insights to an ongoing debate. PMID:34122731
A Pan-Cancer Analysis of the Oncogenic Role of Twinfilin Actin Binding Protein 1 in Human Tumors. PMID:34113576
TTSurv: Exploring the Multi-Gene Prognosis in Thousands of Tumors. PMID:34113575
A Bioinformatics Analysis of the Potential Roles of Aquaporin 4 in Human Brain Tumors: An Immune-Related Process. PMID:34113257
A novel method to identify gene interaction patterns. PMID:34112093
Hyaluronan-mediated motility receptor expression functions as a prognostic biomarker in uterine carcinosarcoma based on bioinformatics analysis. PMID:34111996
Interpreting the Molecular Mechanisms of Yinchenhao Decoction on Hepatocellular Carcinoma through Absorbed Components Based on Network Pharmacology. PMID:34104649
PPFIA4 Promotes Colon Cancer Cell Proliferation and Migration by Enhancing Tumor Glycolysis. PMID:34094943
Bioinformatics Analysis of a Prognostic miRNA Signature and Potential Key Genes in Pancreatic Cancer. PMID:34094925
2-kupl: mapping-free variant detection from DNA-seq data of matched samples. PMID:34090332
Oncogenic Landscape of Somatic Mutations Perturbing Pan-Cancer lncRNA-ceRNA Regulation. PMID:34079798
Pan-cancer analysis of the prognostic value of C12orf75 based on data mining. PMID:34074799
Genetic and biological hallmarks of colorectal cancer. PMID:34074695
Molecular Landscape and Therapeutic Strategies in Cholangiocarcinoma: An Integrated Translational Approach towards Precision Medicine. PMID:34070643
The Detection and Bioinformatic Analysis of Alternative 3' UTR Isoforms as Potential Cancer Biomarkers. PMID:34070203
Biomarker Identification through Multiomics Data Analysis of Prostate Cancer Prognostication Using a Deep Learning Model and Similarity Network Fusion. PMID:34064004
The expression profiles and prognostic values of HSP70s in hepatocellular carcinoma. PMID:34059060
Multiple Reaction Monitoring-Based Targeted Assays for the Validation of Protein Biomarkers in Brain Tumors. PMID:34055594
The Unreasonable Effectiveness of Inverse Reinforcement Learning in Advancing Cancer Research. PMID:34055465
dbGENVOC: database of GENomic Variants of Oral Cancer, with special reference to India. PMID:34048545
Identification of biomarkers complementary to homologous recombination deficiency for improving the clinical outcome of ovarian serous cystadenocarcinoma. PMID:34047476
The roles and prognostic significance of ABI1-TSV-11 expression in patients with left-sided colorectal cancer. PMID:34031495
CDSeqR: fast complete deconvolution for gene expression data from bulk tissues. PMID:34030626
A comprehensive review of m6A/m6Am RNA methyltransferase structures. PMID:34023900
Permutation-based identification of important biomarkers for complex diseases via machine learning models. PMID:34021151
Fenchel duality of Cox partial likelihood with an application in survival kernel learning. PMID:34020756
In silico analysis suggests disruption of interactions between HAMP from hepatocytes and SLC40A1 from macrophages in hepatocellular carcinoma. PMID:34001107
Identification and Validation of SNP-Containing Genes With Prognostic Value in Gastric Cancer via Integrated Bioinformatics Analysis. PMID:33987081
Mining TCGA database for gene expression in ovarian serous cystadenocarcinoma microenvironment. PMID:33987033
Identification of prognosis-related molecular subgroups based on DNA methylation in pancreatic cancer. PMID:33980289
The Immune-Related Gene HCST as a Novel Biomarker for the Diagnosis and Prognosis of Clear Cell Renal Cell Carcinoma. PMID:33968730
Tumor Mutation Burden and Immune Invasion Characteristics in Triple Negative Breast Cancer: Genome High-Throughput Data Analysis. PMID:33968045
A Prognostic Model Based on the Immune-Related lncRNAs in Colorectal Cancer. PMID:33959151
Luminal A Breast Cancer Co-expression Network: Structural and Functional Alterations. PMID:33959148
APE1 and SSRP1 is overexpressed in muscle invasive bladder cancer and associated with poor survival. PMID:33948507
Genetic network and gene set enrichment analyses identify MND1 as potential diagnostic and therapeutic target gene for lung adenocarcinoma. PMID:33941804
Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers. PMID:33941616
Transcriptome Based Estrogen Related Genes Biomarkers for Diagnosis and Prognosis in Non-small Cell Lung Cancer. PMID:33936178
Establishment of a prognostic model of four genes in gastric cancer based on multiple data sets. PMID:33934516
A Panel of Five-lncRNA Signature as a Potential Biomarker for Predicting Survival in Gastric and Thoracic Cancers. PMID:33927753
The Challenges and Strategies of Antisense Oligonucleotide Drug Delivery. PMID:33923688
Precision Medicine and Melanoma: Multi-Omics Approaches to Monitoring the Immunotherapy Response. PMID:33917181
MicroRNA-1226-3p has a tumor-promoting role in osteosarcoma. PMID:33907584
M6ADD: a comprehensive database of m6A modifications in diseases. PMID:33906563
Increasing prediction accuracy of pathogenic staging by sample augmentation with a GAN. PMID:33905431
The expression and prognostic value of the epidermal growth factor receptor family in glioma. PMID:33892666
Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra®. PMID:33889297
Systematic analysis of the function and prognostic value of RNA binding proteins in Colon Adenocarcinoma. PMID:33854615
Identification and validation of the prognostic value of cyclic GMP-AMP synthase-stimulator of interferon (cGAS-STING) related genes in gastric cancer. PMID:33843442
Integrative Pan-Cancer Analysis Reveals Decreased Melatonergic Gene Expression in Carcinogenesis and RORA as a Prognostic Marker for Hepatocellular Carcinoma. PMID:33842355
PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology. PMID:33841428
Tackling Diversity in Prostate Cancer Clinical Trials: A Report From the Diversity Working Group of the IRONMAN Registry. PMID:33835826
A study of transposable element-associated structural variations (TASVs) using a de novo-assembled Korean genome. PMID:33833373
Genomic analysis of pancreatic cancer reveals 3 molecular subtypes with different clinical outcomes. PMID:33832071
Role of tumor mutation burden-related signatures in the prognosis and immune microenvironment of pancreatic ductal adenocarcinoma. PMID:33827590
Downregulated ZNF132 predicts unfavorable outcomes in breast Cancer via Hypermethylation modification. PMID:33827486
An R package for divergence analysis of omics data. PMID:33819273
ORN: Inferring patient-specific dysregulation status of pathway modules in cancer with OR-gate Network. PMID:33819263
Analysis of SEC24D Gene in Breast Cancer Based on UALCAN Database. PMID:33817210
MKL-GRNI: A parallel multiple kernel learning approach for supervised inference of large-scale gene regulatory networks. PMID:33817013
Coupling Machine Learning and Lipidomics as a Tool to Investigate Metabolic Dysfunction-Associated Fatty Liver Disease. A General Overview. PMID:33810079
Aberrations of Chromosomes 1 and 16 in Breast Cancer: A Framework for Cooperation of Transcriptionally Dysregulated Genes. PMID:33808143
Identifying Molecular Signatures of Distinct Modes of Collective Migration in Response to the Microenvironment Using Three-Dimensional Breast Cancer Models. PMID:33804802
The Burden of Post-Translational Modification (PTM)-Disrupting Mutations in the Tumor Matrisome. PMID:33802493
Integrative Data Analytic Framework to Enhance Cancer Precision Medicine. PMID:33796878
Machine Learning for Building Immune Genetic Model in Hepatocellular Carcinoma Patients. PMID:33790969
Novel insights into clear cell renal cell carcinoma prognosis by comprehensive characterization of aberrant alternative splicing signature: a study based on large-scale sequencing data. PMID:33783315
Development of alternative splicing signature in lung squamous cell carcinoma. PMID:33772655
Identifying modules of cooperating cancer drivers. PMID:33769711
An Accurate Tool for Uncovering Cancer Subtypes by Fast Kernel Learning Method to Integrate Multiple Profile Data. PMID:33763416
Classification of Clear Cell Renal Cell Carcinoma based on Tumor Suppressor Genomic Profiling. PMID:33758612
PTENε suppresses tumor metastasis through regulation of filopodia formation. PMID:33755220
The direct miR-874-3p-target FAM84A promotes tumor development in papillary thyroid cancer. PMID:33751775
Appyters: Turning Jupyter Notebooks into data-driven web apps. PMID:33748796
CRISPR/Cas: Advances, Limitations, and Applications for Precision Cancer Research. PMID:33748164
High Expression of CLEC11A Predicts Favorable Prognosis in Acute Myeloid Leukemia. PMID:33747924
Multi-Omics Data Fusion via a Joint Kernel Learning Model for Cancer Subtype Discovery and Essential Gene Identification. PMID:33747053
STATegra: Multi-Omics Data Integration - A Conceptual Scheme With a Bioinformatics Pipeline. PMID:33747045
Prediction of LncRNA-encoded small peptides in glioma and oligomer channel functional analysis using in silico approaches. PMID:33735310
COMSUC: A web server for the identification of consensus molecular subtypes of cancer based on multiple methods and multi-omics data. PMID:33735194
A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets. PMID:33727337
A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer. PMID:33726687
Feature Selection for Breast Cancer Classification by Integrating Somatic Mutation and Gene Expression. PMID:33719339
Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks. PMID:33709075
A multi-scale integrated analysis identifies KRT8 as a pan-cancer early biomarker. PMID:33691026
Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study. PMID:33684886
Integrative Survival Analysis of Breast Cancer with Gene Expression and DNA Methylation Data. PMID:33681976
Visualization and Analysis in the Field of Pan-Cancer Studies and Its Application in Breast Cancer Treatment. PMID:33681260
Differential Interactome Proposes Subtype-Specific Biomarkers and Potential Therapeutics in Renal Cell Carcinomas. PMID:33672271
Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo. PMID:33671096
Recent Advances in Integrative Multi-Omics Research in Breast and Ovarian Cancer. PMID:33669749
Knowledge-Guided "Community Network" Analysis Reveals the Functional Modules and Candidate Targets in Non-Small-Cell Lung Cancer. PMID:33669233
Interleukin-1 receptor-associated kinase 4 as a potential biomarker: Overexpression predicts poor prognosis in patients with glioma. PMID:33664818
Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data from Chinese Glioma Patients. PMID:33662628
A Novel DNA Methylation Signature as an Independent Prognostic Factor in Muscle-Invasive Bladder Cancer. PMID:33659216
Identification of a PLCE1‑regulated competing endogenous RNA regulatory network for esophageal squamous cell carcinoma. PMID:33650665
Multi-dimensional data integration algorithm based on random walk with restart. PMID:33639858
Bioinformatics analysis of the prognosis and biological significance of VCAN in gastric cancer. PMID:33631054
Long non-coding RNA-based signature for predicting prognosis of hepatocellular carcinoma. PMID:33622186
A signature of 13 autophagy‑related gene pairs predicts prognosis in hepatocellular carcinoma. PMID:33622179
Abnormal expression of HOXD11 promotes the malignant behavior of glioma cells and leads to poor prognosis of glioma patients. PMID:33614284
Comprehensive Analysis of Prognostic and Immune Infiltrates for E2F Transcription Factors in Human Pancreatic Adenocarcinoma. PMID:33604289
The expression characteristics and prognostic roles of autophagy-related genes in gastric cancer. PMID:33604190
The immune-related biomarker TEK inhibits the development of clear cell renal cell carcinoma (ccRCC) by regulating AKT phosphorylation. PMID:33602230
Identification of hub genes associated with adult acute myeloid leukemia progression through weighted gene co-expression network analysis. PMID:33592582
Development of an Immune-Related Gene Signature for Prognosis in Melanoma. PMID:33585219
Ranking cancer drivers via betweenness-based outlier detection and random walks. PMID:33568049
Expression of cell divisioncycle-associated genes and their prognostic significance in hepatocellular carcinoma. PMID:33564348
Multi-omic modelling of inflammatory bowel disease with regularized canonical correlation analysis. PMID:33556098
MUC4 is a novel mediator in H. pylori infection-related pancreatic cancer. PMID:33552244
A Novel Prognostic Model of Early-Stage Lung Adenocarcinoma Integrating Methylation and Immune Biomarkers. PMID:33552145
Pan-Cancer analysis of the expression and regulation of matrisome genes across 32 tumor types. PMID:33543003
Identification of key genes and microRNA regulatory network in development and progression of urothelial bladder carcinoma. PMID:33532331
Information-incorporated Gaussian graphical model for gene expression data. PMID:33527365
LAPTM5 Plays a Key Role in the Diagnosis and Prognosis of Testicular Germ Cell Tumors. PMID:33521125
Mutational burden and chromosomal aneuploidy synergistically predict survival from radiotherapy in non-small cell lung cancer. PMID:33514859
High heterogeneity undermines generalization of differential expression results in RNA-Seq analysis. PMID:33509298
Identification of a Five-Autophagy-Related-lncRNA Signature as a Novel Prognostic Biomarker for Hepatocellular Carcinoma. PMID:33505990
Identification of an Immunologic Signature of Lung Adenocarcinomas Based on Genome-Wide Immune Expression Profiles. PMID:33505988
Cryptotanshinone Is a Intervention for ER-Positive Breast Cancer: An Integrated Approach to the Study of Natural Product Intervention Mechanisms. PMID:33505309
Identification of IL10RA by Weighted Correlation Network Analysis and in vitro Validation of Its Association With Prognosis of Metastatic Melanoma. PMID:33490091
Online informatics resources to facilitate cancer target and chemical probe discovery. PMID:33479663
Loss of wild type KRAS in KRASMUT lung adenocarcinoma is associated with cancer mortality and confers sensitivity to FASN inhibitors. PMID:33465697
Breast cancer is marked by specific, Public T-cell receptor CDR3 regions shared by mice and humans. PMID:33465095
Kinase-substrate Edge Biomarkers Provide a More Accurate Prognostic Prediction in ER-negative Breast Cancer. PMID:33450402
Identification of Hub Genes as Potential Prognostic Biomarkers in Cervical Cancer Using Comprehensive Bioinformatics Analysis and Validation Studies. PMID:33447084
Transcriptome-wide high-throughput mapping of protein-RNA occupancy profiles using POP-seq. PMID:33441968
Mitochondria-related core genes and TF-miRNA-hub mrDEGs network in breast cancer. PMID:33439992
Expression and clinical significance of miR-3615 in hepatocellular carcinoma. PMID:33435769
GVES: machine learning model for identification of prognostic genes with a small dataset. PMID:33431999
Cancer Omics in Africa: Present and Prospects. PMID:33425763
circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression. PMID:33425493
An Integrative Computational Approach Based on Expression Similarity Signatures to Identify Protein-Protein Interaction Networks in Female-Specific Cancers. PMID:33424936
Untangling a complex web: Computational analyses of tumor molecular profiles to decode driver mechanisms. PMID:33423960
Identification of key modules and hub genes in glioblastoma multiforme based on co-expression network analysis. PMID:33423377
Noncoding RNAs Serve as the Deadliest Universal Regulators of all Cancers. PMID:33419895
Identification and Validation of Two Lung Adenocarcinoma-Development Characteristic Gene Sets for Diagnosing Lung Adenocarcinoma and Predicting Prognosis. PMID:33408736
Generating real-world evidence from unstructured clinical notes to examine clinical utility of genetic tests: use case in BRCAness. PMID:33407429
Overexpression of TC2N is associated with poor prognosis in gastric cancer. PMID:33403038
The Biological Meaning of Radiomic Features. PMID:33399513
Identification of KIF4A and its effect on the progression of lung adenocarcinoma based on the bioinformatics analysis. PMID:33398330
Identification of lncRNA-mRNA Regulatory Module to Explore the Pathogenesis and Prognosis of Melanoma. PMID:33392203
Long Non-Coding RNAs: The Regulatory Mechanisms, Research Strategies, and Future Directions in Cancers. PMID:33392092
Alteration of Proteotranscriptomic Landscape Reveals the Transcriptional Regulatory Circuits Controlling Key-Signaling Pathways and Metabolic Reprogramming During Tumor Evolution. PMID:33384992
Role of PRDM1 in Tumor Immunity and Drug Response: A Pan-Cancer Analysis. PMID:33384601
Identification of Somatic Mutations in Papanicolaou Smear DNA and Plasma Circulating Cell-Free DNA for Detection of Endometrial and Epithelial Ovarian Cancers: A Pilot Study. PMID:33381450
[MiR-4443 promotes migration and invasion of breast cancer cells by inhibiting PEBP1 expression]. PMID:33380387
Identification of 6 Hub Proteins and Protein Risk Signature of Colorectal Cancer. PMID:33376727
Application of Biological Domain Knowledge Based Feature Selection on Gene Expression Data. PMID:33374969
m5C RNA Methylation Primarily Affects the ErbB and PI3K-Akt Signaling Pathways in Gastrointestinal Cancer. PMID:33365328
SLC12A8 plays a key role in bladder cancer progression and EMT. PMID:33364434
Acyl-CoA Thioesterase 8 and 11 as Novel Biomarkers for Clear Cell Renal Cell Carcinoma. PMID:33362855
FAM83A as a Potential Biological Marker Is Regulated by miR-206 to Promote Cervical Cancer Progression Through PI3K/AKT/mTOR Pathway. PMID:33344485
Comprehensive pathway-related genes signature for prognosis and recurrence of ovarian cancer. PMID:33344083
A New Era for Space Life Science: International Standards for Space Omics Processing. PMID:33336201
Establishment of Immune-related Gene Pair Signature to Predict Lung Adenocarcinoma Prognosis. PMID:33334139
Data structures based on k-mers for querying large collections of sequencing data sets. PMID:33328168
Identification of a Transcriptomic Prognostic Signature by Machine Learning Using a Combination of Small Cohorts of Prostate Cancer. PMID:33324443
Comparative expression analysis of PD-1, PD-L1, and CD8A in lung adenocarcinoma. PMID:33313223
A meta-learning approach for genomic survival analysis. PMID:33311484
Differential genetic mutations of ectoderm, mesoderm, and endoderm-derived tumors in TCGA database. PMID:33308219
A Combined Effect of Expression Levels of Obesity-Related Genes and Clinical Factors on Cancer Survival Rate. PMID:33299884
Genomic investigation of co-targeting tumor immune microenvironment and immune checkpoints in pan-cancer immunotherapy. PMID:33299118
An Integrated Bioinformatic Analysis of the S100 Gene Family for the Prognosis of Colorectal Cancer. PMID:33294444
SNRPB-mediated RNA splicing drives tumor cell proliferation and stemness in hepatocellular carcinoma. PMID:33289700
NCEH1 may be a prognostic biomarker for pancreatic cancer. PMID:33284889
The SIRT3 and SIRT6 Promote Prostate Cancer Progression by Inhibiting Necroptosis-Mediated Innate Immune Response. PMID:33282964
Mastermind: A Comprehensive Genomic Association Search Engine for Empirical Evidence Curation and Genetic Variant Interpretation. PMID:33281875
DNA methylation subtypes for ovarian cancer prognosis. PMID:33278864
Screening of T Cell-Related Long Noncoding RNA-MicroRNA-mRNA Regulatory Networks in Non-Small-Cell Lung Cancer. PMID:33274216
Machine Learning Identifies Robust Matrisome Markers and Regulatory Mechanisms in Cancer. PMID:33266472
Identification and Development of Long Non-coding RNA Associated Regulatory Network in Pancreatic Adenocarcinoma. PMID:33262608
LNX1 Modulates Notch1 Signaling to Promote Expansion of the Glioma Stem Cell Population during Temozolomide Therapy in Glioblastoma. PMID:33255632
SPOCK2 Serves as a Potential Prognostic Marker and Correlates With Immune Infiltration in Lung Adenocarcinoma. PMID:33244319
Tumor Derived SIGLEC Family Genes May Play Roles in Tumor Genesis, Progression, and Immune Microenvironment Regulation. PMID:33240817
Discovering novel driver mutations from pan-cancer analysis of mutational and gene expression profiles. PMID:33232371
Upregulation of KIF20A promotes tumor proliferation and invasion in renal clear cell carcinoma and is associated with adverse clinical outcome. PMID:33232285
IGF2BP2 Promotes Liver Cancer Growth Through an m6A-FEN1-Dependent Mechanism. PMID:33224879
RADIO-IBAG: RADIOMICS-BASED INTEGRATIVE BAYESIAN ANALYSIS OF MULTIPLATFORM GENOMIC DATA. PMID:33224404
Identification of Prognosis-Related Genes in Bladder Cancer Microenvironment across TCGA Database. PMID:33204728
An Integrating Immune-Related Signature to Improve Prognosis of Hepatocellular Carcinoma. PMID:33204302
Identification of two molecular subtypes of dysregulated immune lncRNAs in ovarian cancer. PMID:33203236
Development of cancer prognostic signature based on pan-cancer proteomics. PMID:33200655
A comparison of mRNA and circRNA expression between squamous cell carcinoma and adenocarcinoma of the lungs. PMID:33196759
Nuclear Segmentation in Histopathological Images Using Two-Stage Stacked U-Nets With Attention Mechanism. PMID:33195135
Comprehensive Analysis of ATP6V1s Family Members in Renal Clear Cell Carcinoma With Prognostic Values. PMID:33194650
Prognostic model of invasive ductal carcinoma of the breast based on differentially expressed glycolysis-related genes. PMID:33194424
Identification and validation of prognostic signature for breast cancer based on genes potentially involved in autophagy. PMID:33194339
Identifying M1 Macrophage-Related Genes Through a Co-expression Network to Construct a Four-Gene Risk-Scoring Model for Predicting Thyroid Cancer Prognosis. PMID:33193731
Integration of Online Omics-Data Resources for Cancer Research. PMID:33193699
A Review of Integrative Imputation for Multi-Omics Datasets. PMID:33193667
Bioinformatics Analysis Discovers Microtubular Tubulin Beta 6 Class V (TUBB6) as a Potential Therapeutic Target in Glioblastoma. PMID:33193654
A Novel Six-Gene Signature for Prognosis Prediction in Ovarian Cancer. PMID:33193589
A Novel Signature of 23 Immunity-Related Gene Pairs Is Prognostic of Cutaneous Melanoma. PMID:33193373
DORGE: Discovery of Oncogenes and tumoR suppressor genes using Genetic and Epigenetic features. PMID:33177077
Data mining of immune-related prognostic genes in metastatic melanoma microenvironment. PMID:33169786
Interactions between tumor mutation burden and immune infiltration in ovarian cancer. PMID:33165430
The tumor immune microenvironment transcriptomic subtypes of colorectal cancer for prognosis and development of precise immunotherapy. PMID:33163194
Construction and investigation of a combined hypoxia and stemness index lncRNA-associated ceRNA regulatory network in lung adenocarcinoma. PMID:33148251
LINC00968 can inhibit the progression of lung adenocarcinoma through the miR-21-5p/SMAD7 signal axis. PMID:33147570
Spliceosome-Associated microRNAs Signify Breast Cancer Cells and Portray Potential Novel Nuclear Targets. PMID:33143250
Regulation of Canonical Oncogenic Signaling Pathways in Cancer via DNA Methylation. PMID:33143142
Revealing Prognosis-Related Pathways at the Individual Level by a Comprehensive Analysis of Different Cancer Transcription Data. PMID:33138076
Complete deconvolution of DNA methylation signals from complex tissues: a geometric approach. PMID:33135072
Kernel Fusion Method for Detecting Cancer Subtypes via Selecting Relevant Expression Data. PMID:33133130
lncRNA MRUL Suppressed Non-Small Cell Lung Cancer Cells Proliferation and Invasion by Targeting miR-17-5p/SRSF2 Axis. PMID:33123591
RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis. PMID:33116296
Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth. PMID:33110234
Comprehensive analysis of the expression of SLC30A family genes and prognosis in human gastric cancer. PMID:33110097
CKS1B as Drug Resistance-Inducing Gene-A Potential Target to Improve Cancer Therapy. PMID:33102238
Construction and Characterization of a Synergistic lncRNA-miRNA Network Reveals a Crucial and Prognostic Role of lncRNAs in Colon Cancer. PMID:33101392
PyGNA: a unified framework for geneset network analysis. PMID:33092528
Prediction of Poor Prognosis of HCC by Early Warning Model for Co-Expression of miRNA and mRNA Based on Bioinformatics Analysis. PMID:33089765
Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods. PMID:33076847
Identification of key genes unique to the luminal a and basal-like breast cancer subtypes via bioinformatic analysis. PMID:33066779
A machine learning analysis of a "normal-like" IDH-WT diffuse glioma transcriptomic subgroup associated with prolonged survival reveals novel immune and neurotransmitter-related actionable targets. PMID:33059718
LibMI: An Open Source Library for Efficient Histopathological Image Processing. PMID:33042605
Identification and validation of a ten-gene set variation score as a diagnostic and prognostic stratification tool in hepatocellular carcinoma. PMID:33042448
A Bayesian 2D functional linear model for gray-level co-occurrence matrices in texture analysis of lower grade gliomas. PMID:33035963
Diagnostic and prognostic value of thymidylate synthase expression in breast cancer. PMID:33030246
TOP2A and CENPF are synergistic master regulators activated in cervical cancer. PMID:33023625
Genomic, transcriptomic, and viral integration profiles associated with recurrent/metastatic progression in high-risk human papillomavirus cervical carcinomas. PMID:33017516
The future of digital health with federated learning. PMID:33015372
Prediction of Radiosensitivity in Head and Neck Squamous Cell Carcinoma Based on Multiple Omics Data. PMID:33014019
The relationship between chimeric RNAs and gene fusions: Potential implications of reciprocity in cancer. PMID:33008771
Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis. PMID:33008459
A survey on deep learning in DNA/RNA motif mining. PMID:33005921
Integrative Analysis of Membrane Proteome and MicroRNA Reveals Novel Lung Cancer Metastasis Biomarkers. PMID:33005184
BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A. PMID:33001583
An interactive network of alternative splicing events with prognostic value in geriatric lung adenocarcinoma via the regulation of splicing factors. PMID:33000861
Mammaglobin B may be a prognostic biomarker of uterine corpus endometrial cancer. PMID:32994818
Tac2-N serves an oncogenic role and promotes drug resistance in human gastric cancer cells. PMID:32989391
Matrix Metallopeptidase 14: A Candidate Prognostic Biomarker for Diffuse Large B-Cell Lymphoma. PMID:32974187
How Can Gene-Expression Information Improve Prognostic Prediction in TCGA Cancers: An Empirical Comparison Study on Regularization and Mixed Cox Models. PMID:32973875
High ADAMTS18 expression is associated with poor prognosis in stomach adenocarcinoma. PMID:32963617
Cancer gene expression profiles associated with clinical outcomes to chemotherapy treatments. PMID:32948183
miRTissue ce: extending miRTissue web service with the analysis of ceRNA-ceRNA interactions. PMID:32938402
Developing the novel bioinformatics algorithms to systematically investigate the connections among survival time, key genes and proteins for Glioblastoma multiforme. PMID:32938364
The New Paradigm of Network Medicine to Analyze Breast Cancer Phenotypes. PMID:32932728
BRD4/8/9 are prognostic biomarkers and associated with immune infiltrates in hepatocellular carcinoma. PMID:32927435
Carbonic Anhydrase 4 serves as a Clinicopathological Biomarker for Outcomes and Immune Infiltration in Renal Cell Carcinoma, Lower Grade Glioma, Lung Adenocarcinoma and Uveal Melanoma. PMID:32922550
Potential mechanism of RRM2 for promoting Cervical Cancer based on weighted gene co-expression network analysis. PMID:32922202
Construction of a circRNA-Related ceRNA Prognostic Regulatory Network in Breast Cancer. PMID:32922032
A pan-cancer assessment of alterations of the kinase domain of ULK1, an upstream regulator of autophagy. PMID:32913252
Overexpressed Pseudogene HLA-DPB2 Promotes Tumor Immune Infiltrates by Regulating HLA-DPB1 and Indicates a Better Prognosis in Breast Cancer. PMID:32903535
Human Endogenous Retrovirus Expression Is Associated with Head and Neck Cancer and Differential Survival. PMID:32872377
Methylation of immune-regulatory cytokine genes and pancreatic cancer outcomes. PMID:32867538
Identification of a novel prognostic DNA methylation signature for lung adenocarcinoma based on consensus clustering method. PMID:32860318
Identification of MiR-211-5p as a tumor suppressor by targeting ACSL4 in Hepatocellular Carcinoma. PMID:32859232
Identification of key differentially expressed mRNAs and microRNAs in non-small cell lung cancer using bioinformatics analysis. PMID:32855723
Development of Multiscale Transcriptional Regulatory Network in Esophageal Cancer Based on Integrated Analysis. PMID:32851080
Analysis of Epithelial-Mesenchymal Transition Metabolism Identifies Possible Cancer Biomarkers Useful in Diverse Genetic Backgrounds. PMID:32850411
Prognostic Value of Immune-Related Genes in the Tumor Microenvironment of Bladder Cancer. PMID:32850407
Gene Co-expression Is Distance-Dependent in Breast Cancer. PMID:32850369
A Bioinformatics Research on Novel Mechanism of Compound Kushen Injection for Treating Breast Cancer by Network Pharmacology and Molecular Docking Verification. PMID:32849897
Genome-Wide Transcriptional Analysis Reveals Alternative Splicing Event Profiles in Hepatocellular Carcinoma and Their Prognostic Significance. PMID:32849842
The Biological Significance of Multi-copy Regions and Their Impact on Variant Discovery. PMID:32827758
Advancing Medical Imaging Informatics by Deep Learning-Based Domain Adaptation. PMID:32823306
m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome. PMID:32821938
The three dimensions of somatic evolution: Integrating the role of genetic damage, life-history traits, and aging in carcinogenesis. PMID:32821273
De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection. PMID:32817363
A multinational review: Oesophageal cancer in low to middle-income countries. PMID:32802164
Identification of critical genes in gastric cancer to predict prognosis using bioinformatics analysis methods. PMID:32793728
A three-mRNA status risk score has greater predictive ability compared with a lncRNA-based risk score for predicting prognosis in patients with hepatocellular carcinoma. PMID:32788937
Potential five-mRNA signature model for the prediction of prognosis in patients with papillary thyroid carcinoma. PMID:32782547
Personal Health Information Inference Using Machine Learning on RNA Expression Data from Patients With Cancer: Algorithm Validation Study. PMID:32773372
Machine learning: A powerful tool for gene function prediction in plants. PMID:32765975
Genomic data imputation with variational auto-encoders. PMID:32761097
Classifying Breast Cancer Subtypes Using Deep Neural Networks Based on Multi-Omics Data. PMID:32759821
Gene expression-based clinical predictions in lung adenocarcinoma. PMID:32756002
Mining novel cell glycolysis related gene markers that can predict the survival of colon adenocarcinoma patients. PMID:32744303
KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells. PMID:32743551
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression. PMID:32733879
Integrative Bioinformatics Approaches to Screen Potential Prognostic Immune-Related Genes and Drugs in the Cervical Cancer Microenvironment. PMID:32733542
Genomic analysis of biomarkers related to the prognosis of acute myeloid leukemia. PMID:32724426
Automatic detection of squamous cell carcinoma metastasis in esophageal lymph nodes using semantic segmentation. PMID:32722861
CNSA: a data repository for archiving omics data. PMID:32705130
Establishment of a novel cell cycle-related prognostic signature predicting prognosis in patients with endometrial cancer. PMID:32699528
Gene regulation network analysis reveals core genes associated with survival in glioblastoma multiforme. PMID:32696617
Comprehensive Analysis of Differentially Expressed lncRNAs in Gastric Cancer. PMID:32695786
Comprehensive analysis of the expression of sodium/potassium-ATPase α subunits and prognosis of ovarian serous cystadenocarcinoma. PMID:32684846
Long Non-coding RNA TDRKH-AS1 Promotes Colorectal Cancer Cell Proliferation and Invasion Through the β-Catenin Activated Wnt Signaling Pathway. PMID:32670860
Construction of a Comprehensive Multiomics Map of Hepatocellular Carcinoma and Screening of Possible Driver Genes. PMID:32670354
Association of CXCL13 and Immune Cell Infiltration Signature in Clear Cell Renal Cell Carcinoma. PMID:32669964
Bioinformatics-based analysis of the lncRNA-miRNA-mRNA and TF regulatory networks reveals functional genes in esophageal squamous cell carcinoma. PMID:32662828
Genome-wide analyses of the prognosis-related mRNA alternative splicing landscape and novel splicing factors based on large-scale low grade glioma cohort. PMID:32658870
Improved survival analysis by learning shared genomic information from pan-cancer data. PMID:32657401
REINDEER: efficient indexing of k-mer presence and abundance in sequencing datasets. PMID:32657392
Prognostic and immune regulating roles of YIF1B in Pan-Cancer: a potential target for both survival and therapy response evaluation. PMID:32648580
Weighted correlation gene network analysis reveals a new stemness index-related survival model for prognostic prediction in hepatocellular carcinoma. PMID:32644941
New Analysis Framework Incorporating Mixed Mutual Information and Scalable Bayesian Networks for Multimodal High Dimensional Genomic and Epigenomic Cancer Data. PMID:32625238
Development and validation of a novel immune-related prognostic model in lung squamous cell carcinoma. PMID:32624696
Quiescent stem cell marker genes in glioma gene networks are sufficient to distinguish between normal and glioblastoma (GBM) samples. PMID:32616845
Systems biology comprehensive analysis on breast cancer for identification of key gene modules and genes associated with TNM-based clinical stages. PMID:32616754
An Analysis Regarding the Association Between the ISLR Gene and Gastric Carcinogenesis. PMID:32612640
Identification of SPRR3 as a novel diagnostic/prognostic biomarker for oral squamous cell carcinoma via RNA sequencing and bioinformatic analyses. PMID:32596058
Bioinformatics Analysis of Prognostic miRNA Signature and Potential Critical Genes in Colon Cancer. PMID:32582275
Identification of a Robust Five-Gene Risk Model in Prostate Cancer: A Robust Likelihood-Based Survival Analysis. PMID:32566639
Identification and validation of seven prognostic long non-coding RNAs in oral squamous cell carcinoma. PMID:32566023
Identification of Prion Disease-Related Somatic Mutations in the Prion Protein Gene (PRNP) in Cancer Patients. PMID:32560489
Bladder Cancer at the time of COVID-19 Outbreak. PMID:32549074
Construction and Analysis of a Long Non-Coding RNA-Associated Competing Endogenous RNA Network Identified Potential Prognostic Biomarkers in Luminal Breast Cancer. PMID:32547061
Integrative computational epigenomics to build data-driven gene regulation hypotheses. PMID:32543653
Identification of methylation-driven genes related to the prognosis of papillary renal cell carcinoma: a study based on The Cancer Genome Atlas. PMID:32536823
Comprehensive Analysis of Competing Endogenous RNA (ceRNA) Network Based on RNAs Differentially Expressed in Lung Adenocarcinoma Using The Cancer Genome Atlas (TCGA) Database. PMID:32533823
SURF: integrative analysis of a compendium of RNA-seq and CLIP-seq datasets highlights complex governing of alternative transcriptional regulation by RNA-binding proteins. PMID:32532357
Detecting Prognosis Risk Biomarkers for Colon Cancer Through Multi-Omics-Based Prognostic Analysis and Target Regulation Simulation Modeling. PMID:32528533
Reveal the Regulation Patterns of Prognosis-Related miRNAs and lncRNAs Across Solid Tumors in the Cancer Genome Atlas. PMID:32523951
KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis. PMID:32519739
DSG2 expression is correlated with poor prognosis and promotes early-stage cervical cancer. PMID:32514251
Machine learning-based genome-wide interrogation of somatic copy number aberrations in circulating tumor DNA for early detection of hepatocellular carcinoma. PMID:32512514
Kinesin family members KIF2C/4A/10/11/14/18B/20A/23 predict poor prognosis and promote cell proliferation in hepatocellular carcinoma. PMID:32509165
Identification of immune-related biomarkers associated with tumorigenesis and prognosis in cutaneous melanoma patients. PMID:32508531
Calreticulin couples with immune checkpoints in pancreatic cancer. PMID:32508042
Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors. PMID:32502294
Nine glycolysis-related gene signature predicting the survival of patients with endometrial adenocarcinoma. PMID:32489319
SCDb: an integrated database of stomach cancer. PMID:32487193
Pharmacogenetics: An Important Part of Drug Development with A Focus on Its Application. PMID:32467882
Prognostic value of prostaglandin I2 synthase and its correlation with tumor-infiltrating immune cells in lung cancer, ovarian cancer, and gastric cancer. PMID:32463792
AKNA Is a Potential Prognostic Biomarker in Gastric Cancer and Function as a Tumor Suppressor by Modulating EMT-Related Pathways. PMID:32462010
Identification of Prognostic miRNA Signature and Lymph Node Metastasis-Related Key Genes in Cervical Cancer. PMID:32457603
Comprehensive analysis of competitive endogenous RNAs network reveals potential prognostic lncRNAs in gastric cancer. PMID:32455175
PathwayPCA: an R/Bioconductor Package for Pathway Based Integrative Analysis of Multi-Omics Data. PMID:32430990
Uncovering the prognostic gene signatures for the improvement of risk stratification in cancers by using deep learning algorithm coupled with wavelet transform. PMID:32429941
Metabolomics and Multi-Omics Integration: A Survey of Computational Methods and Resources. PMID:32429287
MCM2 and NUSAP1 Are Potential Biomarkers for the Diagnosis and Prognosis of Pancreatic Cancer. PMID:32420375
Integrative genomics approach identifies molecular features associated with early-stage ovarian carcinoma histotypes. PMID:32409713
STAT1-induced upregulation of lncRNA LINC01123 predicts poor prognosis and promotes the progression of endometrial cancer through miR-516b/KIF4A. PMID:32401659
The expression change of OTUD3-PTEN signaling axis in glioma cells. PMID:32395534
The emerging roles of WBP2 oncogene in human cancers. PMID:32393834
methCancer-gen: a DNA methylome dataset generator for user-specified cancer type based on conditional variational autoencoder. PMID:32393170
BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization. PMID:32392297
Identification of HMG-box family establishes the significance of SOX6 in the malignant progression of glioblastoma. PMID:32388501
Comprehensive analysis of aberrantly expressed long non‑coding RNAs, microRNAs, and mRNAs associated with the competitive endogenous RNA network in cervical cancer. PMID:32377727
Promising diagnostic and prognostic value of six genes in human hepatocellular carcinoma. PMID:32355538
HMGA1-Regulating microRNAs Let-7a and miR-26a are Downregulated in Human Seminomas. PMID:32344629
Genomic analysis and clinical implications of immune cell infiltration in gastric cancer. PMID:32338286
Accurate estimation of cell composition in bulk expression through robust integration of single-cell information. PMID:32332754
Molecular signatures for inflammation vary across cancer types and correlate significantly with tumor stage, sex and vital status of patients. PMID:32330128
Statistics in the Genomic Era. PMID:32325634
Expression based biomarkers and models to classify early and late-stage samples of Papillary Thyroid Carcinoma. PMID:32324757
Development of a risk scoring system for evaluating the prognosis of patients with Her2-positive breast cancer. PMID:32322168
Consistent RNA sequencing contamination in GTEx and other data sets. PMID:32321923
Immune system‑associated genes increase malignant progression and can be used to predict clinical outcome in patients with hepatocellular carcinoma. PMID:32319580
HECTD1 regulates the expression of SNAIL: Implications for epithelial‑mesenchymal transition. PMID:32319576
An Effective Graph Clustering Method to Identify Cancer Driver Modules. PMID:32318558
Computational Oncology in the Multi-Omics Era: State of the Art. PMID:32318338
Comprehensive Map of the Regulated Cell Death Signaling Network: A Powerful Analytical Tool for Studying Diseases. PMID:32316560
Comprehensive insights on pivotal prognostic signature involved in clear cell renal cell carcinoma microenvironment using the ESTIMATE algorithm. PMID:32311223
A Novel Attribute-Based Symmetric Multiple Instance Learning for Histopathological Image Analysis. PMID:32305904
PathME: pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data. PMID:32299344
Elucidation of Functional Roles of Sialic Acids in Cancer Migration. PMID:32296639
Early Diagnosis of Hepatocellular Carcinoma Using Machine Learning Method. PMID:32292778
Emerging role of deep learning-based artificial intelligence in tumor pathology. PMID:32277744
Comparative bioinformatical analysis of pancreatic head cancer and pancreatic body/tail cancer. PMID:32277286
Comprehensive Analysis of the Expression and Prognosis for GBPs in Head and neck squamous cell carcinoma. PMID:32269280
Identification of core genes associated with prostate cancer progression and outcome via bioinformatics analysis in multiple databases. PMID:32266115
Improved Prediction of miRNA-Disease Associations Based on Matrix Completion with Network Regularization. PMID:32260218
GenoPheno: cataloging large-scale phenotypic and next-generation sequencing data within human datasets. PMID:32249310
Triple-Negative Breast Cancer: A Review of Conventional and Advanced Therapeutic Strategies. PMID:32245065
How Machine Learning Will Transform Biomedicine. PMID:32243801
Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets. PMID:32232009
The relationship of human tissue microRNAs with those from body fluids. PMID:32221351
MeCP2 Promotes Colorectal Cancer Metastasis by Modulating ZEB1 Transcription. PMID:32210086
The potential drug for treatment in pancreatic adenocarcinoma: a bioinformatical study based on distinct drug databases. PMID:32206083
An Integrated Meta-Analysis of Secretome and Proteome Identify Potential Biomarkers of Pancreatic Ductal Adenocarcinoma. PMID:32197468
Identification of hub driving genes and regulators of lung adenocarcinoma based on the gene Co-expression network. PMID:32196072
Pan-cancer diagnostic consensus through searching archival histopathology images using artificial intelligence. PMID:32195366
High expression of interleukin-enhancer binding factor 3 predicts poor prognosis in patients with lung adenocarcinoma. PMID:32194712
Fatty acid-binding protein 5 predicts poor prognosis in patients with uveal melanoma. PMID:32194670
Repositioning of Hypoglycemic Drug Linagliptin for Cancer Treatment. PMID:32194417
Identification of Key Components in Colon Adenocarcinoma Using Transcriptome to Interactome Multilayer Framework. PMID:32193399
Machine learning prediction of oncology drug targets based on protein and network properties. PMID:32171238
Segmentation and Classification in Digital Pathology for Glioma Research: Challenges and Deep Learning Approaches. PMID:32153349
The Application of Deep Learning in Cancer Prognosis Prediction. PMID:32150991
Bioinformatics Analysis to Screen the Key Prognostic Genes in Tumor Microenvironment of Bladder Cancer. PMID:32149116
Upregulated Seizure-Related 6 Homolog-Like 2 Is a Prognostic Predictor of Hepatocellular Carcinoma. PMID:32148567
Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability. PMID:32144251
Big data in digital healthcare: lessons learnt and recommendations for general practice. PMID:32139886
Functionally Enigmatic Genes in Cancer: Using TCGA Data to Map the Limitations of Annotations. PMID:32139709
DeepSurvNet: deep survival convolutional network for brain cancer survival rate classification based on histopathological images. PMID:32124225
Targeting Metabolic Deregulation Landscapes in Breast Cancer Subtypes. PMID:32117749
Systemic Analysis of RNA Alternative Splicing Signals Related to the Prognosis for Head and Neck Squamous Cell Carcinoma. PMID:32117741
Comprehensive Review of Web Servers and Bioinformatics Tools for Cancer Prognosis Analysis. PMID:32117725
PLXNC1 Enhances Carcinogenesis Through Transcriptional Activation of IL6ST in Gastric Cancer. PMID:32117710
Disparity between Inter-Patient Molecular Heterogeneity and Repertoires of Target Drugs Used for Different Types of Cancer in Clinical Oncology. PMID:32111026
Enhanced CXCR4 Expression Associates with Increased Gene Body 5-Hydroxymethylcytosine Modification but not Decreased Promoter Methylation in Colorectal Cancer. PMID:32110952
Identification of molecular markers associated with the progression and prognosis of endometrial cancer: a bioinformatic study. PMID:32099532
Pan-cancer mapping of differential protein-protein interactions. PMID:32094374
Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer. PMID:32093698
ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma. PMID:32093682
Risk score based on expression of five novel genes predicts survival in soft tissue sarcoma. PMID:32084007
Prognostic Value and Potential Regulatory Mechanism of Alternative Splicing in Geriatric Breast Cancer. PMID:32079071
Multi-omics Data Integration, Interpretation, and Its Application. PMID:32076369
Predict New Therapeutic Drugs for Hepatocellular Carcinoma Based on Gene Mutation and Expression. PMID:32047745
Long non-coding RNA TCL6 enhances preferential toxicity of paclitaxel to renal cell carcinoma cells. PMID:32047545
'Omics Approaches to Explore the Breast Cancer Landscape. PMID:32039208
Long Non-coding RNAs Involved in Resistance to Chemotherapy in Ovarian Cancer. PMID:32039022
Non-Negative Symmetric Low-Rank Representation Graph Regularized Method for Cancer Clustering Based on Score Function. PMID:32038712
Comprehensive Analysis of Differential Gene Expression to Identify Common Gene Signatures in Multiple Cancers. PMID:32035007
Artificial intelligence and big data facilitated targeted drug discovery. PMID:32030204
Metabolic classification of circulating tumor cells as a biomarker for metastasis and prognosis in breast cancer. PMID:32028979
Notch1/2/3/4 are prognostic biomarker and correlated with immune infiltrates in gastric cancer. PMID:32028262
Methylation‑driven genes PMPCAP1, SOWAHC and ZNF454 as potential prognostic biomarkers in lung squamous cell carcinoma. PMID:32016477
Promoter methylation status of ASC/TMS1/PYCARD is associated with decreased overall survival and TNM status in patients with early stage non-small cell lung cancer (NSCLC). PMID:32010578
Identification of Key Biomarkers in Bladder Cancer: Evidence from a Bioinformatics Analysis. PMID:31991631
Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer. PMID:31979117
Flexible Data Trimming Improves Performance of Global Machine Learning Methods in Omics-Based Personalized Oncology. PMID:31979006
MicroRNA Biomarker hsa-miR-195-5p for Detecting the Risk of Lung Cancer. PMID:31976313
An introduction to deep learning in medical physics: advantages, potential, and challenges. PMID:31972556
Comprehensive molecular characterization of inhibitors of apoptosis proteins (IAPs) for therapeutic targeting in cancer. PMID:31964418
An Optimised Protocol Harnessing Laser Capture Microdissection for Transcriptomic Analysis on Matched Primary and Metastatic Colorectal Tumours. PMID:31959771
Variable Mutations at the p53-R273 Oncogenic Hotspot Position Leads to Altered Properties. PMID:31952808
miR-TV: an interactive microRNA Target Viewer for microRNA and target gene expression interrogation for human cancer studies. PMID:31950188
Correlating Transcriptional Networks to Papillary Renal Cell Carcinoma Survival: A Large-Scale Coexpression Analysis and Clinical Validation. PMID:31948514
Prognostic value of epithelial-mesenchymal transition markers in clear cell renal cell carcinoma. PMID:31915310
BEM: Mining Coregulation Patterns in Transcriptomics via Boolean Matrix Factorization. PMID:31913438
MatchMixeR: a cross-platform normalization method for gene expression data integration. PMID:31904810
Brain Imaging Genomics: Integrated Analysis and Machine Learning. PMID:31902950
Monitoring methylation-driven genes as prognostic biomarkers in patients with lung squamous cell cancer. PMID:31897186
Prognostic implications of the BRAF-V600E mutation in papillary thyroid carcinoma based on a new cut-off age stratification. PMID:31897179
Three-microRNA expression signature predicts survival in triple-negative breast cancer. PMID:31897142
Directional association test reveals high-quality putative cancer driver biomarkers including noncoding RNAs. PMID:31888644
Multi-cancer samples clustering via graph regularized low-rank representation method under sparse and symmetric constraints. PMID:31888442
The exploration of disease-specific gene regulatory networks in esophageal carcinoma and stomach adenocarcinoma. PMID:31888440
Impact of image preprocessing methods on reproducibility of radiomic features in multimodal magnetic resonance imaging in glioblastoma. PMID:31880401
Genetic links between endometriosis and cancers in women. PMID:31879572
PROMO: an interactive tool for analyzing clinically-labeled multi-omic cancer datasets. PMID:31878868
A systematic evaluation of copy number alterations detection methods on real SNP array and deep sequencing data. PMID:31874603
Identification of Differently Expressed Genes Associated With Prognosis and Growth in Colon Adenocarcinoma Based on Integrated Bioinformatics Analysis. PMID:31867042
Identification of lung cancer gene markers through kernel maximum mean discrepancy and information entropy. PMID:31856830
Improved cell composition deconvolution method of bulk gene expression profiles to quantify subsets of immune cells. PMID:31856824
Knowledge Base Commons (KBCommons) v1.1: a universal framework for multi-omics data integration and biological discoveries. PMID:31856718
Identification of prognostic genes in adrenocortical carcinoma microenvironment based on bioinformatic methods. PMID:31856409
Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma. PMID:31853539
7-lncRNA Assessment Model for Monitoring and Prognosis of Breast Cancer Patients: Based on Cox Regression and Co-expression Analysis. PMID:31850229
IBI: Identification of Biomarker Genes in Individual Tumor Samples. PMID:31850079
PRKD2 Promotes Progression and Chemoresistance of AML via Regulating Notch1 Pathway. PMID:31849496
Checkpoint inhibitor failure in hypermutated and mismatch repair-mutated recurrent high-grade gliomas. PMID:31832212
Integrative Analysis Reveals Comprehensive Altered Metabolic Genes Linking with Tumor Epigenetics Modification in Pan-Cancer. PMID:31828117
The Role of Serine Peptidase Inhibitor Kazal Type 13 (SPINK13) as a Clinicopathological and Prognostic Biomarker in Patients with Clear Cell Renal Cell Carcinoma. PMID:31825950
Longitudinal linear combination test for gene set analysis. PMID:31822265
A twenty gene-based gene set variation score reflects the pathological progression from cirrhosis to hepatocellular carcinoma. PMID:31811111
Reduced expression of microRNA-139-5p in hepatocellular carcinoma results in a poor outcome: An exploration the roles of microRNA-139-5p in tumorigenesis, advancement and prognosis at the molecular biological level using an integrated meta-analysis and bioinformatic investigation. PMID:31807180
Identification of key candidate genes and pathways in endometrial cancer: Evidence from bioinformatics analysis. PMID:31807178
Analysis of CASP12 diagnostic and prognostic values in cervical cancer based on TCGA database. PMID:31804677
Genome-wide screening of abberant methylated drivers combined with relative risk loci in bladder cancer. PMID:31794632
A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subtyping. PMID:31774481
Epigenomics of Pancreatic Cancer: A Critical Role for Epigenome-Wide Studies. PMID:31772762
Expression and potential prognostic value of histone family gene signature in breast cancer. PMID:31772649
Ovarian Cancer-Why Lipids Matter. PMID:31769430
Commentary: Prognostication of uveal melanoma based on molecular diagnosis - Are we there yet? PMID:31755429
Prognostication of uveal melanoma is simple and highly predictive using The Cancer Genome Atlas (TCGA) classification: A review. PMID:31755428
Systematic profiling of alternative splicing signature reveals prognostic predictor for cervical cancer. PMID:31744495
Defining Signatures of Arm-Wise Copy Number Change and Their Associated Drivers in Kidney Cancers. PMID:31744086
Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome. PMID:31739726
Purification of viable peripheral blood mononuclear cells for biobanking using a robotized liquid handling workstation. PMID:31718655
LncTarD: a manually-curated database of experimentally-supported functional lncRNA-target regulations in human diseases. PMID:31713618
Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma. PMID:31703694
Genome-wide mutation profiling and related risk signature for prognosis of papillary renal cell carcinoma. PMID:31700863
Melittin inhibits proliferation, migration and invasion of bladder cancer cells by regulating key genes based on bioinformatics and experimental assays. PMID:31691530
Multi-omics Analysis of Microenvironment Characteristics and Immune Escape Mechanisms of Hepatocellular Carcinoma. PMID:31681571
A multi-sample approach increases the accuracy of transcript assembly. PMID:31676772
Role of alternative splicing signatures in the prognosis of glioblastoma. PMID:31674730
Prediction and Analysis of Skin Cancer Progression using Genomics Profiles of Patients. PMID:31673075
The Many Faces of Gene Regulation in Cancer: A Computational Oncogenomics Outlook. PMID:31671657
Unraveling allosteric landscapes of allosterome with ASD. PMID:31665428
Artificial Intelligence in Lung Cancer Pathology Image Analysis. PMID:31661863
A comprehensive genome-wide profiling comparison between HBV and HCV infected hepatocellular carcinoma. PMID:31660973
An eight-mRNA signature predicts the prognosis of patients with bladder urothelial carcinoma. PMID:31660264
LncRNAs as Chromatin Regulators in Cancer: From Molecular Function to Clinical Potential. PMID:31658672
miRTarBase 2020: updates to the experimentally validated microRNA-target interaction database. PMID:31647101
Robust hypergraph regularized non-negative matrix factorization for sample clustering and feature selection in multi-view gene expression data. PMID:31639067
β‑elemene inhibits the generation of peritoneum effusion in pancreatic cancer via suppression of the HIF1A‑VEGFA pathway based on network pharmacology. PMID:31638231
Integrative Analysis Reveals Across-Cancer Expression Patterns and Clinical Relevance of Ribonucleotide Reductase in Human Cancers. PMID:31637211
RARRES1 is a novel immune-related biomarker in GBM. PMID:31632537
MUDENG Expression Profiling in Cohorts and Brain Tumor Biospecimens to Evaluate Its Role in Cancer. PMID:31616474
D-GPM: A Deep Learning Method for Gene Promoter Methylation Inference. PMID:31615113
Deep learning for stage prediction in neuroblastoma using gene expression data. PMID:31610626
Comprehensive investigation of the clinical significance and molecular mechanisms of plasmacytoma variant translocation 1 in sarcoma using genome-wide RNA sequencing data. PMID:31598169
A robust 6-mRNA signature for prognosis prediction of pancreatic ductal adenocarcinoma. PMID:31595147
Effects of ABT-737 combined with irradiation treatment on uterine cervical cancer cells. PMID:31579427
Systematic profiling of a novel prognostic alternative splicing signature in hepatocellular carcinoma. PMID:31578577
Targeting of copper-trafficking chaperones causes gene-specific systemic pathology in Drosophila melanogaster: prospective expansion of mutational landscapes that regulate tumor resistance to cisplatin. PMID:31575544
Personalized treatment options for thyroid cancer: current perspectives. PMID:31571972
The Need for Multi-Omics Biomarker Signatures in Precision Medicine. PMID:31561483
Identification of key genes and microRNAs involved in kidney Wilms tumor by integrated bioinformatics analysis. PMID:31555364
Genome-Wide Profiling of Prognostic Alternative Splicing Pattern in Pancreatic Cancer. PMID:31552163
Genome-wide screening identifies novel genes implicated in cellular sensitivity to BRAFV600E expression. PMID:31548614
Chromosomal Density of Cancer Up-Regulated Genes, Aberrant Enhancer Activity and Cancer Fitness Genes Are Associated with Transcriptional Cis-Effects of Broad Copy Number Gains in Colorectal Cancer. PMID:31546890
Transcriptomic analysis and identification of prognostic biomarkers in cholangiocarcinoma. PMID:31545466
LINC00461 affects the survival of patients with renal cell carcinoma by acting as a competing endogenous RNA for microRNA‑942. PMID:31545458
Biclustering-based association rule mining approach for predicting cancer-associated protein interactions. PMID:31538957
3D spatial organization and network-guided comparison of mutation profiles in Glioblastoma reveals similarities across patients. PMID:31527881
Estrogen receptors promote NSCLC progression by modulating the membrane receptor signaling network: a systems biology perspective. PMID:31511014
Identification of a Specific Gene Module for Predicting Prognosis in Glioblastoma Patients. PMID:31508371
High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma. PMID:31506425
Pathway analysis of genomic pathology tests for prognostic cancer subtyping. PMID:31499184
Prognostic value and immune infiltration of novel signatures in clear cell renal cell carcinoma microenvironment. PMID:31493764
Identification of prognosis-related alternative splicing events in kidney renal clear cell carcinoma. PMID:31489763
C3: Consensus Cancer Driver Gene Caller. PMID:31465854
Identification of clinical trait-related lncRNA and mRNA biomarkers with weighted gene co-expression network analysis as useful tool for personalized medicine in ovarian cancer. PMID:31462944
Tumor Transcriptome Reveals High Expression of IL-8 in Non-Small Cell Lung Cancer Patients with Low Pectoralis Muscle Area and Reduced Survival. PMID:31455042
Development of a 21-miRNA Signature Associated With the Prognosis of Patients With Bladder Cancer. PMID:31448232
Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma. PMID:31446433
Post-transcriptional Regulation of Colorectal Cancer: A Focus on RNA-Binding Proteins. PMID:31440515
SFRP4 expression correlates with epithelial mesenchymal transition-linked genes and poor overall survival in colon cancer patients. PMID:31435461
Parkin gene mutations are not common, but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients. PMID:31429726
Distinct signatures of lung cancer types: aberrant mucin O-glycosylation and compromised immune response. PMID:31429720
Targeting Oncogenic BRAF: Past, Present, and Future. PMID:31426419
Analysis of clinical characteristics of macrophage capping protein (CAPG) gene expressed in glioma based on TCGA data and clinical experiments. PMID:31423196
Discovery of core genes in colorectal cancer by weighted gene co-expression network analysis. PMID:31402962
Artificial intelligence in digital pathology - new tools for diagnosis and precision oncology. PMID:31399699
Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants. PMID:31391007
Why Do Data Users Say Health Care Data Are Difficult to Use? A Cross-Sectional Survey Study. PMID:31389335
Clustering analysis of microRNA and mRNA expression data from TCGA using maximum edge-weighted matching algorithms. PMID:31382962
Survival Analysis of Multi-Omics Data Identifies Potential Prognostic Markers of Pancreatic Ductal Adenocarcinoma. PMID:31379917
Prognostic roles of the transcriptional expression of exportins in hepatocellular carcinoma. PMID:31371628
Next-generation sequencing in liquid biopsy: cancer screening and early detection. PMID:31370908
DNA Methylation Module Network-Based Prognosis and Molecular Typing of Cancer. PMID:31357729
High FREM2 Gene and Protein Expression Are Associated with Favorable Prognosis of IDH-WT Glioblastomas. PMID:31357584
Inferring the Disease-Associated miRNAs Based on Network Representation Learning and Convolutional Neural Networks. PMID:31349729
Quantifying gene selection in cancer through protein functional alteration bias. PMID:31334812
Bioinformatics-based discovery of PYGM and TNNC2 as potential biomarkers of head and neck squamous cell carcinoma. PMID:31324732
Genome‑wide investigation of the clinical significance and prospective molecular mechanisms of kinesin family member genes in patients with lung adenocarcinoma. PMID:31322267
Multilayered control of exon acquisition permits the emergence of novel forms of regulatory control. PMID:31315652
Genomics-Guided Immunotherapy for Precision Medicine in Cancer. PMID:31314580
KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition. PMID:31293655
BioNetStat: A Tool for Biological Networks Differential Analysis. PMID:31293621
Integrated analysis of competing endogenous RNA network revealing potential prognostic biomarkers of hepatocellular carcinoma. PMID:31289599
Increased expression of methionine sulfoxide reductases B3 is associated with poor prognosis in gastric cancer. PMID:31289518
Elevated tumor mutation burden and immunogenic activity in patients with hormone receptor-negative or human epidermal growth factor receptor 2-positive breast cancer. PMID:31289516
Identification of potential diagnostic and therapeutic target genes for lung squamous cell carcinoma. PMID:31289486
Identification of methylation-driven genes related to prognosis in clear-cell renal cell carcinoma. PMID:31273792
Studying metabolic flux adaptations in cancer through integrated experimental-computational approaches. PMID:31272436
Integrating proteomics and transcriptomics for the identification of potential targets in early colorectal cancer. PMID:31268166
Lack of B and T cell reactivity towards IDH1R132H in blood and tumor tissue from LGG patients. PMID:31240524
Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming. PMID:31212628
Integrative analysis of common genes and driver mutations implicated in hormone stimulation for four cancers in women. PMID:31205821
Construction of prognostic risk prediction model of oral squamous cell carcinoma based on co-methylated genes. PMID:31198983
Screening of differentially expressed genes and identification of NUF2 as a prognostic marker in breast cancer. PMID:31198978
Integrated Bioinformatic Analysis of a Competing Endogenous RNA Network Reveals a Prognostic Signature in Endometrial Cancer. PMID:31192139
PLEKHO1 knockdown inhibits RCC cell viability in vitro and in vivo, potentially by the Hippo and MAPK/JNK pathways. PMID:31180521
Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome. PMID:31162827
Investigating the dysfunctional pathogenesis of Wilms' tumor through a multidimensional integration strategy. PMID:31157257
Identifying the Antiproliferative Effect of Astragalus Polysaccharides on Breast Cancer: Coupling Network Pharmacology With Targetable Screening From the Cancer Genome Atlas. PMID:31157164
Hematopoietic-substrate-1 associated protein X-1 (HAX-1) regulates liver cancer cells growth, metastasis, and angiogenesis through Akt. PMID:31132019
Plastic diagnostics: The remaking of disease and evidence in personalized medicine. PMID:31130237
FN1, SPARC, and SERPINE1 are highly expressed and significantly related to a poor prognosis of gastric adenocarcinoma revealed by microarray and bioinformatics. PMID:31127138
Biobanking for necrotizing enterocolitis: Needs and standards. PMID:31126684
Identification of portal vein tumor thrombus with an independent clonal origin in hepatocellular carcinoma via multi-omics data analysis. PMID:31119055
Fibronectin 1 promotes melanoma proliferation and metastasis by inhibiting apoptosis and regulating EMT. PMID:31118673
Identification of Potential Crucial Genes Associated With the Pathogenesis and Prognosis of Endometrial Cancer. PMID:31105744
Titin mutation associated with responsiveness to checkpoint blockades in solid tumors. PMID:31092729
Identification of a putative competitive endogenous RNA network for lung adenocarcinoma using TCGA datasets. PMID:31065463
Bioinformatics identification of lncRNA biomarkers associated with the progression of esophageal squamous cell carcinoma. PMID:31059058
Exploration of prognosis-related microRNA and transcription factor co-regulatory networks across cancer types. PMID:31046554
High Expression of DEPDC1 Promotes Malignant Phenotypes of Breast Cancer Cells and Predicts Poor Prognosis in Patients With Breast Cancer. PMID:31032225
A Simple Competing Endogenous RNA Network Identifies Novel mRNA, miRNA, and lncRNA Markers in Human Cholangiocarcinoma. PMID:31019967
The French glioblastoma biobank (FGB): a national clinicobiological database. PMID:31014363
Predicting synthetic lethal interactions using conserved patterns in protein interaction networks. PMID:30995217
Discovering novel mutation signatures by latent Dirichlet allocation with variational Bayes inference. PMID:30993319
Long Noncoding RNA Expression Signatures of Colon Cancer Based on the ceRNA Network and Their Prognostic Value. PMID:30984308
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner. PMID:30971297
mTOR Signalling in Head and Neck Cancer: Heads Up. PMID:30970654
Construction and Analysis of lncRNA-Mediated ceRNA Network in Cervical Squamous Cell Carcinoma by Weighted Gene Co-Expression Network Analysis. PMID:30965350
Linc01194 acts as an oncogene in colorectal carcinoma and is associated with poor survival outcome. PMID:30962722
Association Analysis of Deep Genomic Features Extracted by Denoising Autoencoders in Breast Cancer. PMID:30959966
A STATISTICAL FRAMEWORK FOR DATA INTEGRATION THROUGH GRAPHICAL MODELS WITH APPLICATION TO CANCER GENOMICS. PMID:30956747
OMICfpp: a fuzzy approach for paired RNA-Seq counts. PMID:30940089
Genomic Common Data Model for Seamless Interoperation of Biomedical Data in Clinical Practice: Retrospective Study. PMID:30912749
Upregulated MMP28 in Hepatocellular Carcinoma Promotes Metastasis via Notch3 Signaling and Predicts Unfavorable Prognosis. PMID:30906212
The expression, significance and function of cancer susceptibility candidate 9 in lung squamous cell carcinoma: A bioinformatics and in vitro investigation. PMID:30896821
Identification of DNA methylation-driven genes in esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas. PMID:30886542
SNP mutation-related genes in breast cancer for monitoring and prognosis of patients: A study based on the TCGA database. PMID:30883028
The Y-linked proto-oncogene TSPY contributes to poor prognosis of the male hepatocellular carcinoma patients by promoting the pro-oncogenic and suppressing the anti-oncogenic gene expression. PMID:30867900
Classifying Breast Cancer Subtypes Using Multiple Kernel Learning Based on Omics Data. PMID:30866472
Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences. PMID:30865299
Semantic workflows for benchmark challenges: Enhancing comparability, reusability and reproducibility. PMID:30864323
The X-linked tumor suppressor TSPX downregulates cancer-drivers/oncogenes in prostate cancer in a C-terminal acidic domain dependent manner. PMID:30863497
Promising diagnostic and prognostic value of E2Fs in human hepatocellular carcinoma. PMID:30863181
Correlations of lncRNAs with cervical lymph node metastasis and prognosis of papillary thyroid carcinoma. PMID:30863094
Population Substructure Has Implications in Validating Next-Generation Cancer Genomics Studies with TCGA. PMID:30857229
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway. PMID:30854129
New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx. PMID:30835723
isma: an R package for the integrative analysis of mutations detected by multiple pipelines. PMID:30819096
Overexpression of BHLHE41, correlated with DNA hypomethylation in 3'UTR region, promotes the growth of human clear cell renal cell carcinoma. PMID:30816499
Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of patients with head and neck cancer. PMID:30816478
Prognostic significance of deregulated microRNAs in uveal melanomas. PMID:30816460
IPCT: Integrated Pharmacogenomic Platform of Human Cancer Cell Lines and Tissues. PMID:30813377
The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism. PMID:30809670
Discovering Cancer Subtypes via an Accurate Fusion Strategy on Multiple Profile Data. PMID:30804977
Comprehensive Genomic Characterization of Parathyroid Cancer Identifies Novel Candidate Driver Mutations and Core Pathways. PMID:30788456
Redefining the IBDs using genome-scale molecular phenotyping. PMID:30787446
CircSMARCA5 Regulates VEGFA mRNA Splicing and Angiogenesis in Glioblastoma Multiforme Through the Binding of SRSF1. PMID:30736462
Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs. PMID:30728774
Prognostic values of GMPS, PR, CD40, and p21 in ovarian cancer. PMID:30701134
Mutation Hotspots in the β-Catenin Gene: Lessons from the Human Cancer Genome Databases. PMID:30699286
Data Lakes, Clouds, and Commons: A Review of Platforms for Analyzing and Sharing Genomic Data. PMID:30691868
Use case driven evaluation of open databases for pediatric cancer research. PMID:30675185
Weighted gene co‑expression network analysis for identifying hub genes in association with prognosis in Wilms tumor. PMID:30664180
Pathway Instability Is an Effective New Mutation-Based Type of Cancer Biomarkers. PMID:30662873
Identification of prognostic genes in colorectal cancer through transcription profiling of multi-stage carcinogenesis. PMID:30655784
High expression of density-regulated re-initiation and release factor drives tumourigenesis and affects clinical outcome. PMID:30655749
Precision medicine review: rare driver mutations and their biophysical classification. PMID:30610579
The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens. PMID:30606230
Optimizing gene set annotations combining GO structure and gene expression data. PMID:30598093
Enabling precision medicine via standard communication of HTS provenance, analysis, and results. PMID:30596645
Systematics for types and effects of DNA variations. PMID:30591019
A comprehensive review of available omics data resources and molecular profiling for precision glioma studies. PMID:30588296
Screening of prognostic biomarkers for endometrial carcinoma based on a ceRNA network. PMID:30581678
Cancer biomarker discovery and translation: proteomics and beyond. PMID:30556752
Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health. PMID:30545954
Exploration of methylation-driven genes for monitoring and prognosis of patients with lung adenocarcinoma. PMID:30498398
canSAR: update to the cancer translational research and drug discovery knowledgebase. PMID:30496479
Co-differential Gene Selection and Clustering Based on Graph Regularized Multi-View NMF in Cancer Genomic Data. PMID:30487464
Single-Cell Transcriptomics in Cancer Immunobiology: The Future of Precision Oncology. PMID:30483257
Transcriptional expressions of Chromobox 1/2/3/6/8 as independent indicators for survivals in hepatocellular carcinoma patients. PMID:30481161
Data-Independent Acquisition Mass Spectrometry To Quantify Protein Levels in FFPE Tumor Biopsies for Molecular Diagnostics. PMID:30481034
CMTCN: a web tool for investigating cancer-specific microRNA and transcription factor co-regulatory networks. PMID:30473937
Imitating Pathologist Based Assessment With Interpretable and Context Based Neural Network Modeling of Histology Images. PMID:30450002
DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis. PMID:30417471
Transcriptomic and genomic profiling of early-stage ovarian carcinomas associated with histotype and overall survival. PMID:30416686
Identification of Six Potentially Long Noncoding RNAs as Biomarkers Involved Competitive Endogenous RNA in Clear Cell Renal Cell Carcinoma. PMID:30406146
From Single Level Analysis to Multi-Omics Integrative Approaches: A Powerful Strategy towards the Precision Oncology. PMID:30373182
Candidate Biomarkers and Molecular Mechanism Investigation for Glioblastoma Multiforme Utilizing WGCNA. PMID:30356407
Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancer. PMID:30323202
Prognostic value of DKK2 from the Dickkopf family in human breast cancer. PMID:30320375
Haplosaurus computes protein haplotypes for use in precision drug design. PMID:30297836
Colonic epithelial miR-31 associates with the development of Crohn's phenotypes. PMID:30282822
An Improved Method for Prediction of Cancer Prognosis by Network Learning. PMID:30279327
psichomics: graphical application for alternative splicing quantification and analysis. PMID:30277515
A Review of Matched-pairs Feature Selection Methods for Gene Expression Data Analysis. PMID:30275937
Treatment with olaparib monotherapy for BRCA2-mutated refractory intrahepatic cholangiocarcinoma: a case report. PMID:30271179
Integrated analysis of transcription factors and targets co-expression profiles reveals reduced correlation between transcription factors and target genes in cancer. PMID:30251028
MaxMIF: A New Method for Identifying Cancer Driver Genes through Effective Data Integration. PMID:30250803
A meta-analysis and bioinformatics exploration of the diagnostic value and molecular mechanism of miR-193a-5p in lung cancer. PMID:30250529
Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing data. PMID:30243491
Integrated Analysis of a Competing Endogenous RNA Network Revealing a Prognostic Signature for Cervical Cancer. PMID:30237984
ColXα1 is a stromal component that colocalizes with elastin in the breast tumor extracellular matrix. PMID:30207088
AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors. PMID:30204897
TAP: a targeted clinical genomics pipeline for detecting transcript variants using RNA-seq data. PMID:30200994
Network-Based Approaches to Explore Complex Biological Systems towards Network Medicine. PMID:30200360
A machine learning approach for somatic mutation discovery. PMID:30185652
Fractalis: a scalable open-source service for platform-independent interactive visual analysis of biomedical data. PMID:30165440
Time-Series Analysis of Tumorigenesis in a Murine Skin Carcinogenesis Model. PMID:30158594
Turning omics data into therapeutic insights. PMID:30149217
Biotinylated amplicon sequencing: A method for preserving DNA samples of limited quantity. PMID:30140723
Construction and analysis of mRNA, miRNA, lncRNA, and TF regulatory networks reveal the key genes associated with prostate cancer. PMID:30138363
Characteristics of The Cancer Genome Atlas cases relative to U.S. general population cancer cases. PMID:30131556
The knockdown of the Mediator complex subunit MED15 restrains urothelial bladder cancer cells' malignancy. PMID:30127891
Genome-scale analysis to identify prognostic microRNA biomarkers in patients with early stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy. PMID:30127641
An integrated bioinformatical analysis to evaluate the role of KIF4A as a prognostic biomarker for breast cancer. PMID:30127624
Evolving systems biology approaches to understanding non-coding RNAs in pulmonary hypertension. PMID:30113078
Mouse models in the era of large human tumour sequencing studies. PMID:30111589
Establishment of a SVM classifier to predict recurrence of ovarian cancer. PMID:30106117
A Survey of Molecular Heterogeneity in Hepatocellular Carcinoma. PMID:30094405
TLR-3 Stimulation Skews M2 Macrophages to M1 Through IFN-αβ Signaling and Restricts Tumor Progression. PMID:30072995
Genome‑scale analysis to identify potential prognostic microRNA biomarkers for predicting overall survival in patients with colon adenocarcinoma. PMID:30066920
Integrated genomic analysis for prediction of survival for patients with liver cancer using The Cancer Genome Atlas. PMID:30065560
Multimodal 3D DenseNet for IDH Genotype Prediction in Gliomas. PMID:30061525
Targeted Suppression and Knockout of ASCT2 or LAT1 in Epithelial and Mesenchymal Human Liver Cancer Cells Fail to Inhibit Growth. PMID:30029480
Identification and Analysis of Human Sex-biased MicroRNAs. PMID:30005964
Alternative empirical Bayes models for adjusting for batch effects in genomic studies. PMID:30001694
An integrated analysis of genome-wide DNA methylation and gene expression data in hepatocellular carcinoma. PMID:29988590
Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients. PMID:29970036
Two critical positions in zinc finger domains are heavily mutated in three human cancer types. PMID:29953437
Pancreatic cancer as a sentinel for hereditary cancer predisposition. PMID:29945567
Optimization of a microfluidics-based next generation sequencing assay for clinical oncology diagnostics. PMID:29911110
Discovering mutated driver genes through a robust and sparse co-regularized matrix factorization framework with prior information from mRNA expression patterns and interaction network. PMID:29871594
Sorting nexin-1 is a candidate tumor suppressor and potential prognostic marker in gastric cancer. PMID:29868263
Expression Differentiation Is Not Helpful in Identifying Prognostic Genes Based on TCGA Datasets. PMID:29858064
Dramatic dysbalancing of the Wnt pathway in breast cancers. PMID:29743726
Candidate genes in gastric cancer identified by constructing a weighted gene co-expression network. PMID:29740513
Identification of potential prognostic microRNA biomarkers for predicting survival in patients with hepatocellular carcinoma. PMID:29713196
Prostate Cancer Genomics: Recent Advances and the Prevailing Underrepresentation from Racial and Ethnic Minorities. PMID:29690565
What Does This Mutation Mean? The Tools and Pitfalls of Variant Interpretation in Lymphoid Malignancies. PMID:29677173
Specific breast cancer prognosis-subtype distinctions based on DNA methylation patterns. PMID:29675884
RNA-seq Reveals the Overexpression of IGSF9 in Endometrial Cancer. PMID:29666643
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. PMID:29625051
Finding cancer driver mutations in the era of big data research. PMID:29611034
Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase. PMID:29542011
PRR4: A novel downregulated gene in laryngeal cancer. PMID:29541239
Unmasking molecular profiles of bladder cancer. PMID:29520382
Identification of a gene expression signature predicting survival in oral cavity squamous cell carcinoma using Monte Carlo cross validation. PMID:29496061
Unexplored therapeutic opportunities in the human genome. PMID:29472638
Five Novel Oncogenic Signatures Could Be Utilized as AFP-Related Diagnostic Biomarkers for Hepatocellular Carcinoma Based on Next-Generation Sequencing. PMID:29442275
miR-221 inhibits autophagy and targets TP53INP1 in colorectal cancer cells. PMID:29434757
Genetic insights into the morass of metastatic heterogeneity. PMID:29422598
lncRNA in HNSCC: challenges and potential. PMID:29416430
Identification of regulatory role of DNA methylation in colon cancer gene expression via systematic bioinformatics analysis. PMID:29381923
Opportunities of next-generation sequencing in non-muscle invasive bladder cancer outcome prediction. PMID:29354491
Discovering Altered Regulation and Signaling Through Network-based Integration of Transcriptomic, Epigenomic, and Proteomic Tumor Data. PMID:29344883
Integrated genomic analyses of lung squamous cell carcinoma for identification of a possible competitive endogenous RNA network by means of TCGA datasets. PMID:29340250
Identification of bladder cancer prognostic biomarkers using an ageing gene-related competitive endogenous RNA network. PMID:29340088
A novel messenger RNA signature as a prognostic biomarker for predicting relapse in pancreatic ductal adenocarcinoma. PMID:29340021
Characterizing genomic differences of human cancer stratified by the TP53 mutation status. PMID:29330617
B-CAN: a resource sharing platform to improve the operation, visualization and integrated analysis of TCGA breast cancer data. PMID:29312567
Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer. PMID:29295608
Integrated MicroRNA-mRNA Analysis Reveals miR-204 Inhibits Cell Proliferation in Gastric Cancer by Targeting CKS1B, CXCL1 and GPRC5A. PMID:29283424
GADD45β Loss Ablates Innate Immunosuppression in Cancer. PMID:29279355
Integrative analysis of lncRNAs and miRNAs with coding RNAs associated with ceRNA crosstalk network in triple negative breast cancer. PMID:29276392
TCGA-assembler 2: software pipeline for retrieval and processing of TCGA/CPTAC data. PMID:29272348
Restoration of type 1 iodothyronine deiodinase expression in renal cancer cells downregulates oncoproteins and affects key metabolic pathways as well as anti-oxidative system. PMID:29272308
Usability and Suitability of the Omics-Integrating Analysis Platform tranSMART for Translational Research and Education. PMID:29270954
Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework. PMID:29254494
Bioinformatics analysis of gene expression profiles to identify causal genes in luminal B2 breast cancer. PMID:29250180
Melanoma Tumor Characteristics: An Analysis of Mutational Burden and Copy Number Alterations by Patient Age and Stage. PMID:29221686
Comparative gene co-expression network analysis of epithelial to mesenchymal transition reveals lung cancer progression stages. PMID:29212455
The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery. PMID:29186335
Colorectal cancer stages transcriptome analysis. PMID:29182684
Non-coding RNA networks in cancer. PMID:29170536
miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions. PMID:29126174
Systematic analyses of glutamine and glutamate metabolisms across different cancer types. PMID:29116024
Phosphatidylinositol 3-kinase (PI3Kα)/AKT axis blockade with taselisib or ipatasertib enhances the efficacy of anti-microtubule drugs in human breast cancer cells. PMID:29100327
The ISB Cancer Genomics Cloud: A Flexible Cloud-Based Platform for Cancer Genomics Research. PMID:29092928
LncRNA PVT1 as an effective biomarker for cancer diagnosis and detection based on transcriptome data and meta-analysis. PMID:29088881
Identification and validation of a prognostic 9-genes expression signature for gastric cancer. PMID:29088749
Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival. PMID:29088295
Identification of the key miRNAs associated with survival time in stomach adenocarcinoma. PMID:29085454
lncRNASNP2: an updated database of functional SNPs and mutations in human and mouse lncRNAs. PMID:29077939
Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons. PMID:29050359
RIFS: a randomly restarted incremental feature selection algorithm. PMID:29026108
Single-cell transcriptomics to explore the immune system in health and disease. PMID:28983043
paraGSEA: a scalable approach for large-scale gene expression profiling. PMID:28973463
Big data management challenges in health research-a literature review. PMID:28968677
Network analysis based on TCGA reveals hub genes in colon cancer. PMID:28947883
Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics. PMID:28941356
Next-Generation Sequencing: The Translational Medicine Approach from "Bench to Bedside to Population". PMID:28930123
Identification of genes associated with histologic tumor grade of esophageal squamous cell carcinoma. PMID:28904855
Associations of two-pore domain potassium channels and triple negative breast cancer subtype in The Cancer Genome Atlas: systematic evaluation of gene expression and methylation. PMID:28899398
Identification of prognostic genes through expression differentiation during metastatic process in lung adenocarcinoma. PMID:28894185
An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma. PMID:28860812
Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains. PMID:28814324
Clinical Relevance of microRNA Expressions in Breast Cancer Validated Using the Cancer Genome Atlas (TCGA). PMID:28766230
VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer. PMID:28733631
UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses. PMID:28732212
BRCA1 and BRCA2 mutations and treatment strategies for breast cancer. PMID:28706734
Network-based approaches that exploit inferred transcription factor activity to analyze the impact of genetic variation on gene expression. PMID:28691107
Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF. PMID:28676500
OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc. PMID:28628118
Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls. PMID:28606096
MYC Deregulation in Primary Human Cancers. PMID:28587062
Analysis of healthy and tumour DNA methylation distributions in kidney-renal-clear-cell-carcinoma using Kullback-Leibler and Jensen-Shannon distance measures. PMID:28518060
Establishment of a Strong Link Between Smoking and Cancer Pathogenesis through DNA Methylation Analysis. PMID:28500316
RNA-Seq based genome-wide analysis reveals loss of inter-chromosomal regulation in breast cancer. PMID:28496157
Bioinformatics in translational drug discovery. PMID:28487472
Identifying biomarkers of papillary renal cell carcinoma associated with pathological stage by weighted gene co-expression network analysis. PMID:28427189
Circumvent the uncertainty in the applications of transcriptional signatures to tumor tissues sampled from different tumor sites. PMID:28427173
Genome-wide DNA methylation analysis reveals molecular subtypes of pancreatic cancer. PMID:28423671
Milestones in pathology-from histology to molecular biology. PMID:28367253
Genomic profiling reveals mutational landscape in parathyroid carcinomas. PMID:28352668
BCIP: a gene-centered platform for identifying potential regulatory genes in breast cancer. PMID:28327601
Transcriptomic analyses of RNA-binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma. PMID:28231410
Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer. PMID:28187158
DeepGene: an advanced cancer type classifier based on deep learning and somatic point mutations. PMID:28155641
The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas. PMID:28123877
Identification of Genetic and Epigenetic Variants Associated with Breast Cancer Prognosis by Integrative Bioinformatics Analysis. PMID:28096648
Identification of Biomarkers for Breast Cancer Using Databases. PMID:28053957
How Can We Treat Cancer Disease Not Cancer Cells? PMID:28052653
The Mutational Landscape of the Oncogenic MZF1 SCAN Domain in Cancer. PMID:28018905
Flexible model-based clustering of mixed binary and continuous data: application to genetic regulation and cancer. PMID:27994031
Endogenous retroviral promoter exaptation in human cancer. PMID:27980689
The ability of human nuclear DNA to cause false positive low-abundance heteroplasmy calls varies across the mitochondrial genome. PMID:27955616
Salivary DNA Methylation Profiling: Aspects to Consider for Biomarker Identification. PMID:27901320
DiseaseMeth version 2.0: a major expansion and update of the human disease methylation database. PMID:27899673
The Emergence of Pan-Cancer CIMP and Its Elusive Interpretation. PMID:27879658
The Role of DNA Methylation in Cancer. PMID:27826838
Dissecting the biological relationship between TCGA miRNA and mRNA sequencing data using MMiRNA-Viewer. PMID:27766936
The bone microenvironment - Multiple players involved in cancer progression. PMID:27761362
Implications of Circadian Rhythm Regulation by microRNAs in Colorectal Cancer. PMID:27747302
Precision targeted therapy of ovarian cancer. PMID:27746277
In silico frameworks for systematic pre-clinical screening of potential anti-leukemia therapeutics. PMID:27689915
Expression and prognostic value of E2F activators in NSCLC and subtypes: a research based on bioinformatics analysis. PMID:27655285
Defining Glomerular Disease in Mechanistic Terms: Implementing an Integrative Biology Approach in Nephrology. PMID:27630182
The association between phosphatase and tensin homolog hypermethylation and patients with breast cancer, a meta-analysis and literature review. PMID:27620353
Systems-level effects of ectopic galectin-7 reconstitution in cervical cancer and its microenvironment. PMID:27558259
Expression and Critical Role of Interleukin Enhancer Binding Factor 2 in Hepatocellular Carcinoma. PMID:27556459
Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer. PMID:27556158
Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in Cancer. PMID:27540857
The biorepository portal toolkit: an honest brokered, modular service oriented software tool set for biospecimen-driven translational research. PMID:27535360
ExSurv: A Web Resource for Prognostic Analyses of Exons Across Human Cancers Using Clinical Transcriptomes. PMID:27528797
Joint analysis of multiple high-dimensional data types using sparse matrix approximations of rank-1 with applications to ovarian and liver cancer. PMID:27478503
Systemic transcriptome analysis of hepatocellular carcinoma. PMID:27460080
TCF/LEF Transcription Factors: An Update from the Internet Resources. PMID:27447672
MUFFINN: cancer gene discovery via network analysis of somatic mutation data. PMID:27333808
Targeted Vaccination against Human α-Lactalbumin for Immunotherapy and Primary Immunoprevention of Triple Negative Breast Cancer. PMID:27322324
A microscopic landscape of the invasive breast cancer genome. PMID:27283966
ICM: a web server for integrated clustering of multi-dimensional biomedical data. PMID:27131784
A bioinformatics approach for precision medicine off-label drug drug selection among triple negative breast cancer patients. PMID:27107440
Survival in acute myeloid leukemia is associated with NKp44 splice variants. PMID:27102296
Deletion and low expression of NFKBIA are associated with poor prognosis in lower-grade glioma patients. PMID:27052952
Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients. PMID:26989022
Special Section Guest Editorial:Radiomics and Imaging Genomics: Quantitative Imaging for Precision Medicine. PMID:26839908
Mutations of Chromatin Structure Regulating Genes in Human Malignancies. PMID:26796307
CrossHub: a tool for multi-way analysis of The Cancer Genome Atlas (TCGA) in the context of gene expression regulation mechanisms. PMID:26773058
Developmental genes significantly afflicted by aberrant promoter methylation and somatic mutation predict overall survival of late-stage colorectal cancer. PMID:26691761
CancerResource--updated database of cancer-relevant proteins, mutations and interacting drugs. PMID:26590406
Extracting tumor tissue immune status from expression profiles: correlating renal cancer prognosis with tumor-associated immunome. PMID:26384298
Use of semantic workflows to enhance transparency and reproducibility in clinical omics. PMID:26289940
Dietary MicroRNA Database (DMD): An Archive Database and Analytic Tool for Food-Borne microRNAs. PMID:26030752
Cancer genomics: from discovery science to personalized medicine PubMed citations: 220.

220 articles citing: Cancer genomics: from discovery science to personalized medicine

Costs of Next-Generation Sequencing Assays in Non-Small Cell Lung Cancer: A Micro-Costing Study. PMID:35892985
The Onset of In-Vivo Dehydration in Gas -Based Intraperitoneal Hyperthermia and Its Cytotoxic Effects on Colon Cancer Cells. PMID:35847916
Construction of a Novel MYC-Associated ceRNA Regulatory Network to Identify Prognostic Biomarkers in Colon Adenocarcinoma. PMID:35847359
Data-Driven Identification of Biomarkers for In Situ Monitoring of Drug Treatment in Bladder Cancer Organoids. PMID:35805961
Flexible Sensing Systems for Cancer Diagnostics. PMID:35760996
Potential of Mitochondrial Ribosomal Genes as Cancer Biomarkers Demonstrated by Bioinformatics Results. PMID:35719986
Identifying network biomarkers of cancer by sample-specific differential network. PMID:35705908
Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma. PMID:35637432
Amplified piezoelectrically actuated on-chip flow switching for a rapid and stable microfluidic fluorescence activated cell sorter. PMID:35520855
Association of breast cancer risk, density, and stiffness: global tissue stiffness on breast MR elastography (MRE). PMID:35501423
Ontologies and Knowledge Graphs in Oncology Research. PMID:35454813
A general calculus of fitness landscapes finds genes under selection in cancers. PMID:35301263
Valid-NEO: A Multi-Omics Platform for Neoantigen Detection and Quantification from Limited Clinical Samples. PMID:35267551
High-intermediate risk endometrial cancer: moving toward a molecularly based risk assessment profile. PMID:35038071
Impact of molecular tumour board discussion on targeted therapy allocation in advanced prostate cancer. PMID:34912074
Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach. PMID:34910921
Personalized medicine of non-gene-specific chemotherapies for non-small cell lung cancer. PMID:34900526
Interpretation of network-based integration from multi-omics longitudinal data. PMID:34883510
Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring. PMID:34830837
Machine learning applications for therapeutic tasks with genomics data. PMID:34693370
Identification of putative actionable alterations in clinically relevant genes in breast cancer. PMID:34455425
Cancer: An unknown territory; rethinking before going ahead. PMID:34291136
Integrative Analysis of Next-Generation Sequencing for Next-Generation Cancer Research toward Artificial Intelligence. PMID:34202427
Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer. PMID:34198846
driveR: a novel method for prioritizing cancer driver genes using somatic genomics data. PMID:34030627
Integrated Genomic and Transcriptomic Analysis reveals key genes for predicting dual-phenotype Hepatocellular Carcinoma Prognosis. PMID:33854600
Characterization of AKT Somatic Mutations in Chinese Breast Cancer Patients. PMID:33854375
Radiomic and Genomic Machine Learning Method Performance for Prostate Cancer Diagnosis: Systematic Literature Review. PMID:33792552
Stem Cell Impairment at the Host-Microbiota Interface in Colorectal Cancer. PMID:33673612
Nanogels Capable of Triggered Release. PMID:33665715
Oncological Ligand-Target Binding Systems and Developmental Approaches for Cancer Theranostics. PMID:33423212
FI-Net: Identification of Cancer Driver Genes by Using Functional Impact Prediction Neural Network. PMID:33244318
Cellular State Transformations Using Deep Learning for Precision Medicine Applications. PMID:33205131
A gene-based survival score for lung adenocarcinoma by multiple transcriptional datasets analysis. PMID:33129284
CT Radiomics in Predicting EGFR Mutation in Non-small Cell Lung Cancer: A Single Institutional Study. PMID:33117680
The difference in knowledge and attitudes of using mobile health applications between actual user and non-user among adults aged 50 and older. PMID:33108792
Implementing a clinical cutting-edge and decision-making activity: an ethnographic teamwork approach to a molecular tumorboard. PMID:33028316
Genomics and Transcriptomics: The Powerful Technologies in Precision Medicine. PMID:32982380
Genome-wide association study-based deep learning for survival prediction. PMID:32974946
Prospective Decision Analysis Study of Clinical Genomic Testing in Metastatic Breast Cancer: Impact on Outcomes and Patient Perceptions. PMID:32923860
Gene expression-based clinical predictions in lung adenocarcinoma. PMID:32756002
Study on the Selection of the Targets of Esophageal Carcinoma and Interventions of Ginsenosides Based on Network Pharmacology and Bioinformatics. PMID:32714406
A frequent somatic mutation in the 3'UTR of GAPDH facilitates the development of ovarian cancer by creating a miR‑125b binding site. PMID:32705257
Organotypic Models in Drug Development "Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development". PMID:32548785
Metastatic breast cancer patient perceptions of somatic tumor genomic testing. PMID:32375690
RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways. PMID:32350291
A decision tree to improve identification of pathogenic mutations in clinical practice. PMID:32151256
Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability. PMID:32144251
Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population. PMID:32098350
Brief introduction of medical database and data mining technology in big data era. PMID:32086994
Operational strategies in US cancer centers of excellence that support the successful accrual of racial and ethnic minorities in clinical trials. PMID:32055746
Turning liabilities into opportunities: Off-target based drug repurposing in cancer. PMID:32044472
Long Non-coding RNAs Involved in Resistance to Chemotherapy in Ovarian Cancer. PMID:32039022
Artificial intelligence and big data facilitated targeted drug discovery. PMID:32030204
The genetics of drug-related movement disorders, an umbrella review of meta-analyses. PMID:32020047
Long Noncoding RNA RAET1K Enhances CCNE1 Expression and Cell Cycle Arrest of Lung Adenocarcinoma Cell by Sponging miRNA-135a-5p. PMID:32010197
Identification of key genes as potential biomarkers for triple‑negative breast cancer using integrating genomics analysis. PMID:31974598
Long-term overall survival and prognostic score predicting survival: the IMPACT study in precision medicine. PMID:31888672
Immunohistochemical Analysis Revealed a Correlation between Musashi-2 and Cyclin-D1 Expression in Patients with Oral Squamous Cells Carcinoma. PMID:31878037
Evaluating the consistency of large-scale pharmacogenomic studies. PMID:31846027
Advancing functional and translational microbiome research using meta-omics approaches. PMID:31810497
Multimodal Composite Iron Oxide Nanoparticles for Biomedical Applications. PMID:31624701
On measuring selection in cancer from subclonal mutation frequencies. PMID:31557163
High expression of bone morphogenetic protein (BMP) 6 and BMP7 are associated with higher immune cell infiltration and better survival in estrogen receptor‑positive breast cancer. PMID:31524275
Three-Dimensional Autofocusing Visual Feedback for Automated Rare Cells Sorting in Fluorescence Microscopy. PMID:31461976
miRNA profile obtained by next‑generation sequencing in metastatic breast cancer patients is able to predict the response to systemic treatments. PMID:31364724
Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs. PMID:31216647
Research Needs for Implementing Cancer Prevention and Early Detection in Developing Countries: From Scientists' to Implementers' Perspectives. PMID:31205949
Novel secretome-to-transcriptome integrated or secreto-transcriptomic approach to reveal liquid biopsy biomarkers for predicting individualized prognosis of breast cancer patients. PMID:31146747
Development of a Colorectal Cancer 3D Micro-tumor Construct Platform From Cell Lines and Patient Tumor Biospecimens for Standard-of-Care and Experimental Drug Screening. PMID:31020445
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner. PMID:30961661
Using association signal annotations to boost similarity network fusion. PMID:30863842
Development of a risk scoring system for patients with papillary thyroid cancer. PMID:30729678
Predict drug sensitivity of cancer cells with pathway activity inference. PMID:30704449
Hypoxia-targeted drug delivery. PMID:30575832
Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health. PMID:30545954
DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis. PMID:30417471
Brain Somatic Mutations in Epileptic Disorders. PMID:30352490
The Genomic Basis of Tumor Regression in Tasmanian Devils (Sarcophilus harrisii). PMID:30321343
A novel long non-coding RNA, AC012456.4, as a valuable and independent prognostic biomarker of survival in oral squamous cell carcinoma. PMID:30128179
Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients. PMID:29970036
Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models. PMID:29874987
Controllable extension of hairpin-structured flaps to allow low-background cascade invasive reaction for a sensitive DNA logic sensor for mutation detection. PMID:29675214
Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells. PMID:29497138
Transcriptome analysis and prognosis of ALDH isoforms in human cancer. PMID:29426835
miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells. PMID:29416005
Break Breast Cancer Addiction by CRISPR/Cas9 Genome Editing. PMID:29344267
Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues. PMID:29337142
B-CAN: a resource sharing platform to improve the operation, visualization and integrated analysis of TCGA breast cancer data. PMID:29312567
Tamoxifen sensitivity-related microRNA-342 is a useful biomarker for breast cancer survival. PMID:29245954
Overexpression of suppressive microRNAs, miR-30a and miR-200c are associated with improved survival of breast cancer patients. PMID:29162923
Applying systems biology to biomedical research and health care: a précising definition of systems medicine. PMID:29162092
Association of Omics Features with Histopathology Patterns in Lung Adenocarcinoma. PMID:29153840
PPARγ sumoylation-mediated lipid accumulation in lung cancer. PMID:29137280
Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT): An MD Anderson Precision Medicine Study. PMID:29082359
Comprehensive Analysis of Cancer-Proteogenome to Identify Biomarkers for the Early Diagnosis and Prognosis of Cancer. PMID:29068423
Topological methods for genomics: present and future directions. PMID:28983521
XCAVATOR: accurate detection and genotyping of copy number variants from second and third generation whole-genome sequencing experiments. PMID:28934930
Implementation and utilization of the molecular tumor board to guide precision medicine. PMID:28915716
Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations. PMID:28912564
A data mining approach for identifying pathway-gene biomarkers for predicting clinical outcome: A case study of erlotinib and sorafenib. PMID:28792525
Prediction-Oriented Marker Selection (PROMISE): With Application to High-Dimensional Regression. PMID:28785367
Clinical Relevance of microRNA Expressions in Breast Cancer Validated Using the Cancer Genome Atlas (TCGA). PMID:28766230
Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF. PMID:28676500
More Is Better: Recent Progress in Multi-Omics Data Integration Methods. PMID:28670325
Quantification of within-sample genetic heterogeneity from SNP-array data. PMID:28607403
Somatic Mutations Drive Distinct Imaging Phenotypes in Lung Cancer. PMID:28566328
The spike-and-slab lasso Cox model for survival prediction and associated genes detection. PMID:28472220
Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. PMID:28348404
Detecting truly clonal alterations from multi-region profiling of tumours. PMID:28344344
Systems Pharmacology-Based Discovery of Natural Products for Precision Oncology Through Targeting Cancer Mutated Genes. PMID:28294568
Transcriptomic analyses of RNA-binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma. PMID:28231410
New options in the management of intractable ALK(+) metastatic non-small-cell lung cancer. PMID:28210140
Recent progress in single-cell cancer genomics. PMID:28126650
Frequent amplification of receptor tyrosine kinase genes in welldifferentiated/ dedifferentiated liposarcoma. PMID:28099935
A time-and-motion approach to micro-costing of high-throughput genomic assays. PMID:27803594
The Spike-and-Slab Lasso Generalized Linear Models for Prediction and Associated Genes Detection. PMID:27799277
Defining Glomerular Disease in Mechanistic Terms: Implementing an Integrative Biology Approach in Nephrology. PMID:27630182
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1. PMID:27600491
ExSurv: A Web Resource for Prognostic Analyses of Exons Across Human Cancers Using Clinical Transcriptomes. PMID:27528797
Integration of Multi-Modal Biomedical Data to Predict Cancer Grade and Patient Survival. PMID:27493999
The value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancers. PMID:27338857
Transcriptome sequencing uncovers a three-long noncoding RNA signature in predicting breast cancer survival. PMID:27338266
Predictive value of ex vivo biodynamic imaging in determining response to chemotherapy in dogs with spontaneous non-Hodgkin's lymphomas: a preliminary study. PMID:27280042
Personalized in vitro cancer models to predict therapeutic response: Challenges and a framework for improvement. PMID:27218886
JAG1 Is Associated with Poor Survival through Inducing Metastasis in Lung Cancer. PMID:26930648
Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor. PMID:26918358
Mutation pattern is an influential factor on functional mutation rates in cancer. PMID:26865835
Reads meet rotamers: structural biology in the age of deep sequencing. PMID:26658741
Systematic Prioritization of Druggable Mutations in ∼5000 Genomes Across 16 Cancer Types Using a Structural Genomics-based Approach. PMID:26657081
Perspectives on research activity in the USA on Cancer Precision Medicine. PMID:26531706
The La-Related Proteins, a Family with Connections to Cancer. PMID:26501340
Patient-centric trials for therapeutic development in precision oncology. PMID:26469047
CDK7-dependent transcriptional addiction in triple-negative breast cancer. PMID:26406377
Preclinical mouse cancer models: a maze of opportunities and challenges. PMID:26406370
Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer. PMID:26370119
Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes. PMID:26307061
A New Era of Low-Dose Radiation Epidemiology. PMID:26231501
Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease. PMID:26220939
Big Data: Astronomical or Genomical? PMID:26151137
Genetic heterogeneity in cholangiocarcinoma: a major challenge for targeted therapies. PMID:26142706
Suspension arrays based on nanoparticle-encoded microspheres for high-throughput multiplexed detection. PMID:26021602
Estrogen receptor mutations and their role in breast cancer progression. PMID:25928204
Characterization and identification of hidden rare variants in the human genome. PMID:25903059
Induced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous System. PMID:25794298
miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression. PMID:25698578
The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge. PMID:25691825
Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation. PMID:25598308
Patient-specific driver gene prediction and risk assessment through integrated network analysis of cancer omics profiles. PMID:25572314
Translational cancer research: balancing prevention and treatment to combat cancer globally. PMID:25515230
The UCSC Cancer Genomics Browser: update 2015. PMID:25392408
Classification models for clear cell renal carcinoma stage progression, based on tumor RNAseq expression trained supervised machine learning algorithms. PMID:25374611
Functional consequences of somatic mutations in cancer using protein pocket-based prioritization approach. PMID:25360158
Robust prediction of anti-cancer drug sensitivity and sensitivity-specific biomarker. PMID:25329067
Short hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathway. PMID:25285958
Statistical methods for detecting differentially methylated loci and regions. PMID:25278959
The potential of microRNAs in personalized medicine against cancers. PMID:25243170
Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. PMID:25147954
The promise of methylation on beads for cancer detection and treatment. PMID:25136840
Three-dimensional in vitro tumor models for cancer research and drug evaluation. PMID:25116894
Bioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancer. PMID:25096367
Synergy and competition between cancer genome sequencing and epigenome mapping projects. PMID:25031623
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis. PMID:24952744
Principles and methods of integrative genomic analyses in cancer. PMID:24759209
Prediction and prioritization of rare oncogenic mutations in the cancer Kinome using novel features and multiple classifiers. PMID:24743239
Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis. PMID:24657165
Combining multidimensional genomic measurements for predicting cancer prognosis: observations from TCGA. PMID:24632304
Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging. PMID:24631862
Deregulation of cell signaling in cancer. PMID:24561200
The gene regulatory network for breast cancer: integrated regulatory landscape of cancer hallmarks. PMID:24550935
Advances in molecular biomarkers for gastric cancer: miRNAs as emerging novel cancer markers. PMID:24456939
Prostate cancer: from the pathophysiologic implications of some genetic risk factors to translation in personalized cancer treatments. PMID:24407349
Enhancing systems medicine beyond genotype data by dynamic patient signatures: having information and using it too. PMID:24312119
In vitro models of tumor vessels and matrix: engineering approaches to investigate transport limitations and drug delivery in cancer. PMID:24309015
Strategies to modulate heritable epigenetic defects in cellular machinery: lessons from nature. PMID:24275784
Impact of exome sequencing in inflammatory bowel disease. PMID:24187447
Activating ESR1 mutations in hormone-resistant metastatic breast cancer. PMID:24185510
Making connections: using networks to stratify human tumors. PMID:24173383
Cancer genomics identifies disrupted epigenetic genes. PMID:24104525
Single-cell mutational profiling and clonal phylogeny in cancer. PMID:24056532
Network-based stratification of tumor mutations. PMID:24037242
A novel algorithm for simplification of complex gene classifiers in cancer. PMID:23913937
Structural analysis of mitochondrial mutations reveals a role for bigenomic protein interactions in human disease. PMID:23874847
Revealing selection in cancer using the predicted functional impact of cancer mutations. Application to nomination of cancer drivers. PMID:23819556
Integrating multi-platform genomic data using hierarchical Bayesian relevance vector machines. PMID:23809014
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. PMID:23788652
FGFR fusions in the driver's seat. PMID:23749526
Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis. PMID:23681892
Laparoscopic total gastrectomy and gastric cancer genome architecture: lessons, cautions, and promises. PMID:23660723
From finger pricks to point-and-click. PMID:23601677
Identification of targetable FGFR gene fusions in diverse cancers. PMID:23558953
The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells. PMID:23549172
CancerDR: cancer drug resistance database. PMID:23486013
From single protein to colorectal cancer genome landscape and network biology-based biomarkers. PMID:23443481
Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. PMID:23401433
Collections of simultaneously altered genes as biomarkers of cancer cell drug response. PMID:23338612
Personalized nanomedicine: future medicine for cancer treatment. PMID:23326194
Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes. PMID:23295441
Architecture of pharmacogenomic associations: structures with functional foundations or castles made of sand? PMID:23252941
Activating HER2 mutations in HER2 gene amplification negative breast cancer. PMID:23220880
It's about time: lessons for solid tumors from chronic myelogenous leukemia therapy. PMID:23204432
Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes. PMID:23091610
The autoimmune side of heart and lung diseases. PMID:23054981
Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative. PMID:22966018
From drug discovery to biomarker-driven clinical trials in lymphoma. PMID:22965151
Recurrent R-spondin fusions in colon cancer. PMID:22895193
Thioredoxin reductase is inhibited by the carbamoylating activity of the anticancer sulfonylhydrazine drug laromustine. PMID:22864532
A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts. PMID:22848790
Personalizing lung cancer prevention through a reverse migration strategy. PMID:22752582
Managing drug resistance in cancer: lessons from HIV therapy. PMID:22673150
Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells. PMID:22461507
Cancer: Solving an age-old problem. PMID:22378123
Cancer biomarkers: selecting the right drug for the right patient. PMID:22322254
Translating cancer 'omics' to improved outcomes. PMID:22301133
Clonal evolution in cancer. PMID:22258609
Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils. PMID:21953712
Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies. PMID:21941554
Genetics, genomics, and cancer risk assessment: State of the Art and Future Directions in the Era of Personalized Medicine. PMID:21858794
A pilot clinical study of treatment guided by personalized tumorgrafts in patients with advanced cancer. PMID:21673092
Somatic variation and cancer: therapies lost in the mix. PMID:21643984
Making sense of cancer genomic data PubMed citations: 155.

155 articles citing: Making sense of cancer genomic data

Activation of PPARγ in bladder cancer via introduction of the long arm of human chromosome 9. PMID:35154423
Distinct genetic landscape and a low response to doxorubicin in a luminal-A breast cancer cell line of Pakistani origin. PMID:34495459
SuMO-Fil: Supervised multi-omic filtering prior to performing network analysis. PMID:34343218
Gene expression analysis of MCF7 cell lines of breast cancer treated with herbal extract of Cissampelos pareira revealed association with viral diseases. PMID:33907720
A clinical study on the factors associated with nasopharyngeal carcinoma among the Chinese population. PMID:33732348
Identification of significantly mutated subnetworks in the breast cancer genome. PMID:33436820
Postzygotic Somatic Mutations in the Human Brain Expand the Threshold-Liability Model of Schizophrenia. PMID:33192734
Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors. PMID:32852769
CRISPR and transposon in vivo screens for cancer drivers and therapeutic targets. PMID:32811551
Identification of Prognostic Organic Cation and Anion Transporters in Different Cancer Entities by In Silico Analysis. PMID:32599841
The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver. PMID:32587399
Visualizing and interpreting cancer genomics data via the Xena platform. PMID:32444850
Whole transcriptome signature for prognostic prediction (WTSPP): application of whole transcriptome signature for prognostic prediction in cancer. PMID:32144347
Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome. PMID:31739726
Lung Carcinoma Presenting as a Superior Vena Cava Syndrome, Burnt and Twice Reborn as Adrenal and Facial Tumors. PMID:31723507
MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM. PMID:31690663
Circular RNAs: pivotal molecular regulators and novel diagnostic and prognostic biomarkers in non-small cell lung cancer. PMID:31630262
circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression. PMID:31623653
Predicting stage-specific cancer related genes and their dynamic modules by integrating multiple datasets. PMID:31074385
Transcriptome analysis identifies metallothionein as biomarkers to predict recurrence in hepatocellular cacinoma. PMID:31056863
Comparable Genomic Copy Number Aberrations Differ across Astrocytoma Malignancy Grades. PMID:30871102
Genomics for All: International Open Science Genomics Projects and Capacity Building in the Developing World. PMID:30828348
Precise targeting of POLR2A as a therapeutic strategy for human triple negative breast cancer. PMID:30804480
Development of a risk scoring system for patients with papillary thyroid cancer. PMID:30729678
Temporal dynamics in meta longitudinal RNA-Seq data. PMID:30679697
The many faces of mathematical modelling in oncology. PMID:30485129
DEP domain containing 1 predicts prognosis of hepatocellular carcinoma patients and regulates tumor proliferation and metastasis. PMID:30417471
Using Semantic Web Technologies to Enable Cancer Genomics Discovery at Petabyte Scale. PMID:30283230
MERIT: Systematic Analysis and Characterization of Mutational Effect on RNA Interactome Topology. PMID:30153342
Precision Medicine in Relapsed and Refractory Childhood Cancers: Single-center Experience, Literature Review, and Meta-analysis. PMID:30089094
Bayesian variable selection with graphical structure learning: Applications in integrative genomics. PMID:30059495
A comprehensive analysis of prognosis prediction models based on pathway‑level, gene‑level and clinical information for glioblastoma. PMID:30015853
Cancer CRISPR Screens In Vivo. PMID:29709259
RNA-seq Reveals the Overexpression of IGSF9 in Endometrial Cancer. PMID:29666643
Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. PMID:29503867
Beyond genomics: understanding exposotypes through metabolomics. PMID:29373992
NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis. PMID:29176703
Tumor molecular profiling of NSCLC patients using next generation sequencing. PMID:29130105
Statistical Contributions to Bioinformatics: Design, Modeling, Structure Learning, and Integration. PMID:29129969
Identification of candidate genes for devil facial tumour disease tumourigenesis. PMID:28821767
An Optimal Mean Based Block Robust Feature Extraction Method to Identify Colorectal Cancer Genes with Integrated Data. PMID:28819308
Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance. PMID:28781887
A Novel Unsupervised Algorithm for Biological Process-based Analysis on Cancer. PMID:28680165
Circular RNAs: Biogenesis, Function and Role in Human Diseases. PMID:28634583
A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo. PMID:28530655
Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer. PMID:28402947
Identification of outcome-related driver mutations in cancer using conditional co-occurrence distributions. PMID:28240231
Transcriptomic analyses of RNA-binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma. PMID:28231410
Functionally-focused algorithmic analysis of high resolution microarray-CGH genomic landscapes demonstrates comparable genomic copy number aberrations in MSI and MSS sporadic colorectal cancer. PMID:28231327
SMITE: an R/Bioconductor package that identifies network modules by integrating genomic and epigenomic information. PMID:28100166
Molecular predictive markers in tumors of the gastrointestinal tract. PMID:27895815
Identification of gene-drug interactions that impact patient survival in TCGA. PMID:27716027
The biorepository portal toolkit: an honest brokered, modular service oriented software tool set for biospecimen-driven translational research. PMID:27535360
Upregulation of Cyclooxygenase-2/Prostaglandin E2 (COX-2/PGE2) Pathway Member Multiple Drug Resistance-Associated Protein 4 (MRP4) and Downregulation of Prostaglandin Transporter (PGT) and 15-Prostaglandin Dehydrogenase (15-PGDH) in Triple-Negative Breast Cancer. PMID:27257388
A phase 1 study of buparlisib and bevacizumab in patients with metastatic renal cell carcinoma progressing on vascular endothelial growth factor-targeted therapies. PMID:27198170
Characterizing genomic alterations in cancer by complementary functional associations. PMID:27088724
Registered report: Diverse somatic mutation patterns and pathway alterations in human cancers. PMID:26894955
Multiplex Preamplification of Serum DNA to Facilitate Reliable Detection of Extremely Rare Cancer Mutations in Circulating DNA by Digital PCR. PMID:26752305
TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data. PMID:26704973
Notes for developing a molecular test for the full characterization of circulating tumor cells. PMID:26543333
Classification of Cancer Primary Sites Using Machine Learning and Somatic Mutations. PMID:26539502
Exploratory biomarker analysis for treatment response in KRAS wild type metastatic colorectal cancer patients who received cetuximab plus irinotecan. PMID:26486455
Oncogenomic portals for the visualization and analysis of genome-wide cancer data. PMID:26484415
Targeting tumor suppressor genes for cancer therapy. PMID:26445307
Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential. PMID:26391647
Copy number alterations detected by whole-exome and whole-genome sequencing of esophageal adenocarcinoma. PMID:26374103
Synthetic dosage lethality in the human metabolic network is highly predictive of tumor growth and cancer patient survival. PMID:26371301
Multiple signatures of a disease in potential biomarker space: Getting the signatures consensus and identification of novel biomarkers. PMID:26100469
Oncogenes and tumor suppressor genes: comparative genomics and network perspectives. PMID:26099335
Molecular Markers in Low-Grade Glioma-Toward Tumor Reclassification. PMID:26050585
CEMP1 Induces Transformation in Human Gingival Fibroblasts. PMID:26011628
TopFed: TCGA tailored federated query processing and linking to LOD. PMID:25937882
Widespread macromolecular interaction perturbations in human genetic disorders. PMID:25910212
ENCAPP: elastic-net-based prognosis prediction and biomarker discovery for human cancers. PMID:25887568
Generating a focused view of disease ontology cancer terms for pan-cancer data integration and analysis. PMID:25841438
Analysis of human upstream open reading frames and impact on gene expression. PMID:25800702
Protein domain-level landscape of cancer-type-specific somatic mutations. PMID:25794154
A map of directional genetic interactions in a metazoan cell. PMID:25748138
Computational characterisation of cancer molecular profiles derived using next generation sequencing. PMID:25691827
miRNA-target gene regulatory networks: A Bayesian integrative approach to biomarker selection with application to kidney cancer. PMID:25639276
A proteome-scale map of the human interactome network. PMID:25416956
The UCSC Cancer Genomics Browser: update 2015. PMID:25392408
Classification models for clear cell renal carcinoma stage progression, based on tumor RNAseq expression trained supervised machine learning algorithms. PMID:25374611
Bayesian disease classification using copy number data. PMID:25336897
A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation. PMID:25329316
The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma. PMID:25298407
Short hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathway. PMID:25285958
One patient, two lesions, two oncogenic drivers of gastric cancer. PMID:25222187
Gene Therapies for Cancer: Strategies, Challenges and Successes. PMID:25196387
The Candidate Cancer Gene Database: a database of cancer driver genes from forward genetic screens in mice. PMID:25190456
Precision therapy for lymphoma--current state and future directions. PMID:25135367
Approaches to integrating germline and tumor genomic data in cancer research. PMID:25115441
Bioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancer. PMID:25096367
Functional characterization of breast cancer using pathway profiles. PMID:25041817
A highly recurrent RPS27 5'UTR mutation in melanoma. PMID:24913145
Superficial scrapings from breast tumors is a source for biobanking and research purposes. PMID:24776644
2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. PMID:24619206
Deregulation of microRNA expression in thyroid tumors. PMID:24599686
SAVI: a statistical algorithm for variant frequency identification. PMID:24564980
Cancer Systems Biology: a peek into the future of patient care? PMID:24492837
Integrative gene set analysis of multi-platform data with sample heterogeneity. PMID:24489370
Bionimbus: a cloud for managing, analyzing and sharing large genomics datasets. PMID:24464852
Integrative genomics with mediation analysis in a survival context. PMID:24454535
Chromosome 10, frequently lost in human melanoma, encodes multiple tumor-suppressive functions. PMID:24453001
Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells. PMID:24401838
Systematic genomic identification of colorectal cancer genes delineating advanced from early clinical stage and metastasis. PMID:24308539
Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia. PMID:24170027
Intragenic breakpoint: a marker of genome instability in glioblastoma. PMID:24145229
Integrative genomic and functional profiling of the pancreatic cancer genome. PMID:24041470
Emerging patterns of somatic mutations in cancer. PMID:24022702
Network and data integration for biomarker signature discovery via network smoothed T-statistics. PMID:24019896
Has discovery-based cancer research been a bust? PMID:24002944
Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE). PMID:23986566
The role of balanced training and testing data sets for binary classifiers in bioinformatics. PMID:23874456
Revealing selection in cancer using the predicted functional impact of cancer mutations. Application to nomination of cancer drivers. PMID:23819556
From human genome to cancer genome: the first decade. PMID:23817046
A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival. PMID:23796897
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer. PMID:23666744
IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer. PMID:23594372
Pathway-based personalized analysis of cancer. PMID:23547110
Drilling into big cancer-genome data. PMID:23538863
Molecular dissection of microsatellite instable colorectal cancer. PMID:23454900
Ehd4 encodes a novel and Oryza-genus-specific regulator of photoperiodic flowering in rice. PMID:23437005
Identifying master regulators of cancer and their downstream targets by integrating genomic and epigenomic features. PMID:23424118
Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. PMID:23321323
Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer. PMID:23319804
STOP gene Phactr4 is a tumor suppressor. PMID:23319639
Objective assessment of cancer genes for drug discovery. PMID:23274470
Medulloblastomics: the end of the beginning. PMID:23175120
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis. PMID:23161690
iBAG: integrative Bayesian analysis of high-dimensional multiplatform genomics data. PMID:23142963
Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes. PMID:23132910
Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes. PMID:23091610
Challenges in identifying candidate amplification targets in human cancers: chromosome 8q21 as a case study. PMID:23050042
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. PMID:23028188
Next-generation sequencing in breast cancer: first take home messages. PMID:23014189
Bioinformatics for cancer immunology and immunotherapy. PMID:22986455
What are we learning from the cancer genome? PMID:22965149
Interactome of Radiation-Induced microRNA-Predicted Target Genes. PMID:22924026
ROS-activated anticancer prodrugs: a new strategy for tumor-specific damage. PMID:22900465
Spectrum of somatic mitochondrial mutations in five cancers. PMID:22891333
Toward personalized cancer nanomedicine - past, present, and future. PMID:22858688
Viral quasispecies evolution. PMID:22688811
A methodological approach to unravel organ-specific breast cancer metastasis. PMID:22628182
Integrated Analysis Reveals hsa-miR-142 as a Representative of a Lymphocyte-Specific Gene Expression and Methylation Signature. PMID:22570537
Emerging insights into the molecular and cellular basis of glioblastoma. PMID:22508724
An emerging toolkit for targeted cancer therapies. PMID:22301131
Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients. PMID:22186935
Conserved RB functions in development and tumor suppression. PMID:22180086
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. PMID:22158988
Quasispecies as a matter of fact: viruses and beyond. PMID:21945638
Cancer research: past, present and future. PMID:21918542
Genome-based versus gene-based theory of cancer: possible implications for clinical practice. PMID:21857118
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. PMID:21840483
Genome-wide approaches for cancer gene discovery. PMID:21757246
The future of cancer genomics PubMed citations: 19.

19 articles citing: The future of cancer genomics

Functionally Enigmatic Genes in Cancer: Using TCGA Data to Map the Limitations of Annotations. PMID:32139709
Three-microRNA expression signature predicts survival in triple-negative breast cancer. PMID:31897142
Inclusiveness and ethical considerations for observational, translational, and clinical cancer health disparity research. PMID:31502259
Integrated bioinformatics analysis to identify 15 hub genes in breast cancer. PMID:31423162
A comprehensive review of available omics data resources and molecular profiling for precision glioma studies. PMID:30588296
Single-Cell Transcriptomics in Cancer Immunobiology: The Future of Precision Oncology. PMID:30483257
Data-Independent Acquisition Mass Spectrometry To Quantify Protein Levels in FFPE Tumor Biopsies for Molecular Diagnostics. PMID:30481034
Using Semantic Web Technologies to Enable Cancer Genomics Discovery at Petabyte Scale. PMID:30283230
Emerging application of genomics-guided therapeutics in personalized lung cancer treatment. PMID:29911108
Non-coding RNA networks in cancer. PMID:29170536
The Cancer Genomics Cloud: Collaborative, Reproducible, and Democratized-A New Paradigm in Large-Scale Computational Research. PMID:29092927
Implications of MicroRNAs in Oncolytic Virotherapy. PMID:28725635
Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer. PMID:28454214
Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with Deregulation of Extrinsic and Intrinsic Cell Death Pathways. PMID:28039268
The bone microenvironment - Multiple players involved in cancer progression. PMID:27761362
Unravelling tumour heterogeneity using next-generation imaging: radiomics, radiogenomics, and habitat imaging. PMID:27742105
ExSurv: A Web Resource for Prognostic Analyses of Exons Across Human Cancers Using Clinical Transcriptomes. PMID:27528797
A microscopic landscape of the invasive breast cancer genome. PMID:27283966
The Influence of Tissue Ischemia Time on RNA Integrity and Patient-Derived Xenografts (PDX) Engraftment Rate in a Non-Small Cell Lung Cancer (NSCLC) Biobank. PMID:26731692

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cancer
metasource: Fairsharing.org
version: FAIRsharing.org: TCGA; The Cancer Genome Atlas; DOI: https://doi.org/10.25504/FAIRsharing.m8wewa; Last edited: Jan. 3, 2020, 3:17 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

dna
metasource: re3data.org
version: re3data.org: Cancer GenomeAtlas Data Portal; editing status 2021-09-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3K34M last accessed: 2022-11-04

rna
metasource: re3data.org
version: re3data.org: Cancer GenomeAtlas Data Portal; editing status 2021-09-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3K34M last accessed: 2022-11-04

bioinformatics
metasource: re3data.org
version: re3data.org: Cancer GenomeAtlas Data Portal; editing status 2021-09-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3K34M last accessed: 2022-11-04

cancer detection
metasource: re3data.org
version: re3data.org: Cancer GenomeAtlas Data Portal; editing status 2021-09-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3K34M last accessed: 2022-11-04

cancer prevention
metasource: re3data.org
version: re3data.org: Cancer GenomeAtlas Data Portal; editing status 2021-09-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3K34M last accessed: 2022-11-04

disease
metasource: re3data.org
version: re3data.org: Cancer GenomeAtlas Data Portal; editing status 2021-09-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3K34M last accessed: 2022-11-04

genomics
metasource: re3data.org
version: re3data.org: Cancer GenomeAtlas Data Portal; editing status 2021-09-08; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3K34M last accessed: 2022-11-04

cancer dna rna bioinformatics cancer detection cancer prevention disease genomics

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Cancer Genomics Hub

The Cancer Immunome Atlas

National Cancer Institute's Genomic Data Commons

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Clinical Proteomic Tumor Analysis Consortium Data Portal

Broad GDAC Firehose

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CanGEM

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CancerGenes

NCI Center for Strategic Scientific Initiatives Data Coordinating Center

CGIdb

Cancer Genome Interpreter Cancer Biomarkers database

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