Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function.
PMID:34980917
Enhanced epigenetic profiling of classical human monocytes reveals a specific signature of healthy aging in the DNA methylome.
PMID:34796338
ReMap 2022: a database of Human, Mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments.
PMID:34751401
Defining the Role of Nuclear Factor (NF)-κB p105 Subunit in Human Macrophage by Transcriptomic Analysis of NFKB1 Knockout THP1 Cells.
PMID:34721373
SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits.
PMID:34493297
CellCall: integrating paired ligand-receptor and transcription factor activities for cell-cell communication.
PMID:34331449
Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations.
PMID:33268804
Exploring functionally annotated transcriptional consensus regulatory elements with CONREL.
PMID:33186463
A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer.
PMID:32859160
Dynamical gene regulatory networks are tuned by transcriptional autoregulation with microRNA feedback.
PMID:32737375
DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance.
PMID:32718321
Hierarchical cooperation of transcription factors from integration analysis of DNA sequences, ChIP-Seq and ChIA-PET data.
PMID:32039697
Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy.
PMID:31919106
NicheNet: modeling intercellular communication by linking ligands to target genes.
PMID:31819264
A comprehensive resource for retrieving, visualizing, and integrating functional genomics data.
PMID:31818883
ReMap 2020: a database of regulatory regions from an integrative analysis of Human and Arabidopsis DNA-binding sequencing experiments.
PMID:31665499
Regulatory annotation of genomic intervals based on tissue-specific expression QTLs.
PMID:31504167
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.
PMID:31477735
TAGOOS: genome-wide supervised learning of non-coding loci associated to complex phenotypes.
PMID:31045203
Associations between Maternal Tobacco Smoke Exposure and the Cord Blood [Formula: see text] DNA Methylome.
PMID:31039056
Mechanism of Action for HDAC Inhibitors-Insights from Omics Approaches.
PMID:30939743
RECAP reveals the true statistical significance of ChIP-seq peak calls.
PMID:30824903
Genetic association and transcriptome integration identify contributing genes and tissues at cystic fibrosis modifier loci.
PMID:30807572
Enrichment of Genomic Pathways Based on Differential DNA Methylation Associated With Chronic Postsurgical Pain and Anxiety in Children: A Prospective, Pilot Study.
PMID:30639570
ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.
PMID:30478421
TFmapper: A Tool for Searching Putative Factors Regulating Gene Expression Using ChIP-seq Data.
PMID:30416387
Diesel exhaust and house dust mite allergen lead to common changes in the airway methylome and hydroxymethylome.
PMID:30090644
Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations.
PMID:29895819
LOLAweb: a containerized web server for interactive genomic locus overlap enrichment analysis.
PMID:29878235
Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs.
PMID:29855537
Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.
PMID:29808619
Nasal DNA methylation is associated with childhood asthma.
PMID:29692198
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity.
PMID:29662164
Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region.
PMID:29348432
Systematic target function annotation of human transcription factors.
PMID:29325558
ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments.
PMID:29126285
DNA methylation at enhancers identifies distinct breast cancer lineages.
PMID:29123100
Beyond genome-wide scan: Association of a cis-regulatory NCR3 variant with mild malaria in a population living in the Republic of Congo.
PMID:29121672
Orchid: a novel management, annotation and machine learning framework for analyzing cancer mutations.
PMID:29106441
Integrative Analysis of Transcription Factor Combinatorial Interactions Using a Bayesian Tensor Factorization Approach.
PMID:29033978
Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state.
PMID:28946896
Identification of a p53-repressed gene module in breast cancer cells.
PMID:28915555
Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.
PMID:28877031
Dissecting the genomic activity of a transcriptional regulator by the integrative analysis of omics data.
PMID:28819152
Integrative whole-genome sequence analysis reveals roles of regulatory mutations in BCL6 and BCL2 in follicular lymphoma.
PMID:28765546
Association of a functional TNF variant with Plasmodium falciparum parasitaemia in a congolese population.
PMID:28703132
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
PMID:28628103
Intervene: a tool for intersection and visualization of multiple gene or genomic region sets.
PMID:28569135
DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion.
PMID:28533693
Detecting the Molecular System Signatures of Idiopathic Pulmonary Fibrosis through Integrated Genomic Analysis.
PMID:28484236
CHD1 regulates cell fate determination by activation of differentiation-induced genes.
PMID:28475736
ConTra v3: a tool to identify transcription factor binding sites across species, update 2017.
PMID:28472390
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
PMID:28408400
Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner.
PMID:28369619
Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics.
PMID:28171547
Contextual Refinement of Regulatory Targets Reveals Effects on Breast Cancer Prognosis of the Regulome.
PMID:28103241
Inferring condition-specific targets of human TF-TF complexes using ChIP-seq data.
PMID:28068916
Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay.
PMID:27782208
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline.
PMID:27716038
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.
PMID:27677335
BRD4 localization to lineage-specific enhancers is associated with a distinct transcription factor repertoire.
PMID:27651452
Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA).
PMID:27585267
A microRNA-328 binding site in PAX6 is associated with centrotemporal spikes of rolandic epilepsy.
PMID:27386500
Goldmine integrates information placing genomic ranges into meaningful biological contexts.
PMID:27257071
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.
PMID:27127234
Recent advances in ChIP-seq analysis: from quality management to whole-genome annotation.
PMID:26979602
Gene expression changes in damaged osteoarthritic cartilage identify a signature of non-chondrogenic and mechanical responses.
PMID:26973327
The Inflammatory Transcription Factors NFκB, STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human Kidney.
PMID:26678048
Modeling co-occupancy of transcription factors using chromatin features.
PMID:26590261
LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor.
PMID:26508757
Androgen receptor profiling predicts prostate cancer outcome.
PMID:26412853
By the company they keep: interaction networks define the binding ability of transcription factors.
PMID:26089389