CentrosomeDB
Names
More detailed information about this field from each metasource.
CentrosomeDB
metasource: Fairsharing.org
version: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:29.705867
centrosomedb
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:29.705867
Names
More detailed information about this field from each metasource.
CentrosomeDB
metasource: Fairsharing.orgversion: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:29.705867
centrosomedb
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:29.705867
Names
More detailed information about this field from each metasource.
CentrosomeDB
metasource: Fairsharing.orgversion: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:29.705867
centrosomedb
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:29.705867
This source may no longer be available. No known URL could be resolved successfully.
CentrosomeDB is a collection of human and drosophila centrosomal genes that were reported in the literature and other sources. The database offers the possibility to study the evolution, function, and structure of the centrosome. They have compiled information from many sources, including Gene Ontology, disease-association, single nucleotide polymorphisms, and associated gene expression experiments.
Description
More detailed information about this field from each metasource.
CentrosomeDB is a collection of human and drosophila centrosomal genes that were reported in the literature and other sources. The database offers the possibility to study the evolution, function, and structure of the centrosome. They have compiled information from many sources, including Gene Ontology, disease-association, single nucleotide polymorphisms, and associated gene expression experiments.
metasource: Fairsharing.orgversion: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
We present the second generation of centrosomeDB, available online at http://centrosome.cnb.csic.es, with a significant expansion of 1357 human and drosophila centrosomal genes and their corresponding information. The centrosome of animal cells takes part in important biological processes such as the organization of the interphase microtubule cytoskeleton and the assembly of the mitotic spindle. The active research done during the past decades has produced lots of data related to centrosomal proteins. Unfortunately, the accumulated data is dispersed among diverse and heterogeneous sources of information. We believe that the availability of a repository collecting curated evidences of centrosomal proteins would constitute a key resource for the scientific community. This was our first motivation to introduce CentrosomeDB in NAR database issue in 2009, collecting a set of human centrosomal proteins that were reported in the literature and other sources. The intensive use of this resource during these years has encouraged us to present this new expanded version. Using our database, the researcher is offered the possibility to study the evolution, function, and structure of the centrosome. We have compiled information from many sources, including Gene Ontology, disease-association, single nucleotide polymorphisms, and associated gene expression experiments. Special interest has been paid to protein-protein interaction.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Set of human and fly genes encoding proteins that are localized in the centrosome, either as centrosome constituents or as centrosome visitors. Genes have been considered as centrosomal on the basis of different kinds of evidences including high-throughput proteomics assays, annotations in public databases and orthology relationships to centrosomal genes in closely related species (e.g. mouse).
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:29.705867
Webpage:
http://centrosome.cnb.csic.esWebpage
More detailed information about this field from each metasource.
http://centrosome.cnb.csic.es
metasource: Fairsharing.orgversion: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
http://centrosome.cnb.csic.es/human/centrosome
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:29.705867
Publications:
Publications
More detailed information about this field from each metasource.
CentrosomeDB: a new generation of the centrosomal proteins database for Human and Drosophila melanogaster
PMID: 24270791
metasource: Fairsharing.org
version: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:29.705867
http://dx.doi.org/10.1093/nar/gkt1126
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
CentrosomeDB: a new generation of the centrosomal proteins database for Human and Drosophila melanogaster
PMID: 24270791
metasource: Fairsharing.org
version: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:29.705867
http://dx.doi.org/10.1093/nar/gkt1126
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
-
CentrosomeDB: a new generation of the centrosomal proteins database for Human and Drosophila melanogaster
PubMed citations: 28.
28 articles citing: CentrosomeDB: a new generation of the centrosomal proteins database for Human and Drosophila melanogaster
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity. PMID:35674692
Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly. PMID:35505659
The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification. PMID:35089929
The Transformation of the Centrosome into the Basal Body: Similarities and Dissimilarities between Somatic and Male Germ Cells and Their Relevance for Male Fertility. PMID:34571916
SAPs as a new model to probe the pathway of centriole and centrosome assembly. PMID:33960367
ANKRD26 recruits PIDD1 to centriolar distal appendages to activate the PIDDosome following centrosome amplification. PMID:33350495
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome. PMID:32553112
With Age Comes Maturity: Biochemical and Structural Transformation of a Human Centriole in the Making. PMID:32526902
Drosophila Sas-6, Ana2 and Sas-4 self-organise into macromolecular structures that can be used to probe centriole and centrosome assembly. PMID:32409564
WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication. PMID:31874114
Evidence that a positive feedback loop drives centrosome maturation in fly embryos. PMID:31498081
NudC-like protein 2 restrains centriole amplification by stabilizing HERC2. PMID:31427565
Spatial and proteomic profiling reveals centrosome-independent features of centriolar satellites. PMID:31304627
Trisomy 21 Represses Cilia Formation and Function. PMID:30100262
NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization. PMID:29899413
A novel atypical sperm centriole is functional during human fertilization. PMID:29880810
Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation. PMID:29425198
The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling. PMID:28814505
Centrosome - a promising anti-cancer target. PMID:28008224
Myc-binding protein orthologue interacts with AKAP240 in the central pair apparatus of the Chlamydomonas flagella. PMID:27287193
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. PMID:26638075
Identification of Genes Uniquely Expressed in the Germ-Line Tissues of the Jewel Wasp Nasonia vitripennis. PMID:26464360
Centrosome function and assembly in animal cells. PMID:26373263
Probing mammalian centrosome structure using BioID proximity-dependent biotinylation. PMID:26175438
The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM. PMID:26157019
MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle. PMID:25392421
A network-based approach to dissect the cilia/centrosome complex interactome. PMID:25102769
The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation. PMID:24656740 - http://dx.doi.org/10.1093/nar/gkt1126
Tags:
Tags
More detailed information about this field from each metasource.
centrosome
metasource: Fairsharing.org
version: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein identification
metasource: Fairsharing.org
version: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
region
metasource: Fairsharing.org
version: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein sequence databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
protein localization and targeting
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
molecular biology
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:29.705867
Tags
More detailed information about this field from each metasource.
centrosome
metasource: Fairsharing.orgversion: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein identification
metasource: Fairsharing.orgversion: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
region
metasource: Fairsharing.orgversion: FAIRsharing.org: CentrosomeDB; CentrosomeDB; DOI: https://doi.org/10.25504/FAIRsharing.34pfmc; Last edited: Jan. 8, 2019, 1:20 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
protein sequence databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
protein localization and targeting
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
molecular biology
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:29.705867
centrosome protein identification region protein sequence protein localization and targeting molecular biology
Need help integrating and/or managing biomedical data?