Tumor Associated Gene database
Names
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Tumor Associated Gene database
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
TAG
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Names
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Tumor Associated Gene database
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
TAG
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Names
More detailed information about this field from each metasource.
Tumor Associated Gene database
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
TAG
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The tumor-associated gene (TAG) database was designed to utilize information from well-characterized oncogenes and tumor suppressor genes to facilitate cancer research. All target genes were identified through text-mining approach from the PubMed database.
Description
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The tumor-associated gene (TAG) database was designed to utilize information from well-characterized oncogenes and tumor suppressor genes to facilitate cancer research. All target genes were identified through text-mining approach from the PubMed database.
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
The completion of human genome sequence has advanced a gigantic step toward a new era of biomedical research. Though the sequence itself is not the key for many currently unanswered questions related to human diseases, it sheds light on potential genetic solution of these diseases. We believe that the available annotations including physical characterization and functional protein domains of known tumor-related genes can be used to study the mechanisms underlying tumorigenesis. The tumor-associated gene (TAG; http://www.binfo.ncku.edu.tw/TAG) database was designed to utilize information from well-characterized oncogenes and tumor suppressor genes to facilitate cancer research. All target genes were identified through text-mining approach from the PubMed database. A semi-automatic information retrieving engine was built to collect specific information of these target genes from various resources and store in the TAG database. The information are arranged into five tables including ¡§Gene content¡¨, ¡§Protein domain/family¡¨, ¡§Gene Ontology¡¨, ¡§Disorder & Mutation¡¨, and ¡§Cross reference¡¨. At current stage, TAG database contains information for 198 oncogenes and 167 tumor suppressor genes that were known to be involved in the tumorigenesis in at least one cancer type. In addition, 151 genes that are known to be involved in oncogenesis but the genes actions have not been classified were also collected in the TAG database. We have designed user-friendly web interfaces that provide functions in searching and analysis of TAG information. Furthermore, we categorized all TAG domains and generate a weight matrix table to provide additional analysis in "oncogenic potential" for any customer-provided protein. The TAG is an integrated database that collected only well studied gene in related to oncogenesis. Beside to provide comprehensive information of well-known tumor-related genes to promote biomedical studies, our final goal is to identify novel TAG and study their role in tumorigenesis using a more systemic approach.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://www.binfo.ncku.edu.tw/TAG/GeneDoc.phpWebpage
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http://www.binfo.ncku.edu.tw/TAG/GeneDoc.php
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Licence:
Name: Open Data Commons (ODC) Public Domain Dedication and Licence (PDDL) 1.0Licence name
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Open Data Commons (ODC) Public Domain Dedication and Licence (PDDL) 1.0
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Licence URL
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http://opendatacommons.org/licenses/pddl/1.0/
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Publications:
Publications
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In silico identification of oncogenic potential of fyn-related kinase in hepatocellular carcinoma
PMID: 23267173
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
Publications
More detailed information about this field from each metasource.
In silico identification of oncogenic potential of fyn-related kinase in hepatocellular carcinoma
PMID: 23267173
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
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In silico identification of oncogenic potential of fyn-related kinase in hepatocellular carcinoma
PubMed citations: 73.
73 articles citing: In silico identification of oncogenic potential of fyn-related kinase in hepatocellular carcinoma
Multivariate competing endogenous RNA network characterization for cancer microRNA biomarker discovery: a novel bioinformatics model with application to prostate cancer metastasis. PMID:35821682
Isolation of a Human Betaretrovirus from Patients with Primary Biliary Cholangitis. PMID:35632628
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. PMID:34900668
A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma. PMID:34569064
S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation. PMID:33523865
Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia. PMID:33233470
CENPE, PRC1, TTK, and PLK4 May Play Crucial Roles in the Osteosarcoma Progression. PMID:33176597
Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned so Far. PMID:32498343
Identification of key differentially expressed genes and gene mutations in breast ductal carcinoma in situ using RNA-seq analysis. PMID:32156290
Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans. PMID:31827597
Oncogenes, tumor suppressor and differentiation genes represent the oldest human gene classes and evolve concurrently. PMID:31712655
DNA methylation profiling identifies potentially significant epigenetically-regulated genes in glioblastoma multiforme. PMID:31423235
miRDRN-miRNA disease regulatory network: a tool for exploring disease and tissue-specific microRNA regulatory networks. PMID:31404401
Protective potential of miR-146a-5p and its underlying molecular mechanism in diverse cancers: a comprehensive meta-analysis and bioinformatics analysis. PMID:31285693
miR-19 promotes the proliferation of clear cell renal cell carcinoma by targeting the FRK-PTEN axis. PMID:31043790
Diagnostic and prognostic value of CEP55 in clear cell renal cell carcinoma as determined by bioinformatics analysis. PMID:30896867
Plasma miR-21, miR-155, miR-10b, and Let-7a as the potential biomarkers for the monitoring of breast cancer patients. PMID:30568292
Roles of Cyclin A, Myc, Jun and Ppm1l in tumourigenic transformation of NIH3T3 cell. PMID:30555065
The Overexpression of CD80 and ISG15 Are Associated with the Progression and Metastasis of Breast Cancer by a Meta-Analysis Integrating Three Microarray Datasets. PMID:30411299
Exploring the molecular pathogenesis associated with T-cell prolymphocytic leukemia based on a comprehensive bioinformatics analysis. PMID:29928415
Multiproteomic and Transcriptomic Analysis of Oncogenic β-Catenin Molecular Networks. PMID:29747501
Exploring the molecular mechanisms of osteosarcoma by the integrated analysis of mRNAs and miRNA microarrays. PMID:29620143
Identification of potential key genes and high-frequency mutant genes in prostate cancer by using RNA-Seq data. PMID:29616087
Identification of key genes associated with bladder cancer using gene expression profiles. PMID:29375713
FRK inhibits breast cancer cell migration and invasion by suppressing epithelial-mesenchymal transition. PMID:29348886
An integrative analysis of DNA methylation in osteosarcoma. PMID:29234590
Proteomic profiling of human HepG2 cells treated with hesperidin using antibody array. PMID:28849065
Molecular mechanisms of breast cancer metastasis by gene expression profile analysis. PMID:28791367
Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas. PMID:28627654
Silencing TAK1 alters gene expression signatures in bladder cancer cells. PMID:28521404
Identification of molecular characteristics induced by radiotherapy in rectal cancer based on microarray data. PMID:28454466
Identification of genes associated with tongue cancer in patients with a history of tobacco and/or alcohol use. PMID:28356939
Analysis of gene expression changes associated with human carcinoma-associated fibroblasts in non-small cell lung carcinoma. PMID:28231844
Therapeutic effects of Euphorbia Pekinensis and Glycyrrhiza glabra on Hepatocellular Carcinoma Ascites Partially Via Regulating the Frk-Arhgdib-Inpp5d-Avpr2-Aqp4 Signal Axis. PMID:28165501
Co-expression network analysis of long noncoding RNAs (IncRNAs) and cancer genes revealsSFTA1P and CASC2abnormalities in lung squamous cell carcinoma. PMID:28118064
Altered Pathway Analyzer: A gene expression dataset analysis tool for identification and prioritization of differentially regulated and network rewired pathways. PMID:28084397
Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins. PMID:28008934
Analysis of the molecular mechanism of osteosarcoma using a bioinformatics approach. PMID:27899966
Potential molecular characteristics in situ in response to repetitive UVB irradiation. PMID:27829444
Microarray data analysis to identify crucial genes regulated by CEBPB in human SNB19 glioma cells. PMID:27716259
Bioinformatics analysis of the molecular mechanism of diffuse intrinsic pontine glioma. PMID:27698822
Hsa-miR-137, hsa-miR-520e and hsa-miR-590-3p perform crucial roles in Lynch syndrome. PMID:27602130
Identification of differentially expressed genes in salivary adenoid cystic carcinoma cells associated with metastasis. PMID:27478471
Predicting associations between microRNAs and target genes in breast cancer by bioinformatics analyses. PMID:27446395
Identification of candidate genes for myeloma-induced osteocyte death based on microarray data. PMID:27405725
Gene expression profiling analysis of ovarian cancer. PMID:27347159
Identification of key genes in glioblastoma-associated stromal cells using bioinformatics analysis. PMID:27313730
CoReCG: a comprehensive database of genes associated with colon-rectal cancer. PMID:27114494
Subtypes of HPV-Positive Head and Neck Cancers Are Associated with HPV Characteristics, Copy Number Alterations, PIK3CA Mutation, and Pathway Signatures. PMID:27091409
Identification of colorectal cancer-restricted microRNAs and their target genes based on high-throughput sequencing data. PMID:27069368
Time course analysis based on gene expression profile and identification of target molecules for colorectal cancer. PMID:27013928
The identification of age-associated cancer markers by an integrative analysis of dynamic DNA methylation changes. PMID:26949191
Identification of genes and pathways associated with pancreatic ductal adenocarcinoma by bioinformatics analyses. PMID:26893748
Identification of genes and signaling pathways associated with squamous cell carcinoma by bioinformatics analysis. PMID:26893747
Bioinformatics analysis of hepatitis C virus genotype 2a-induced human hepatocellular carcinoma in Huh7 cells. PMID:26811688
Role of NSC319726 in ovarian cancer based on the bioinformatics analyses. PMID:26719703
The potential role of PHF6 as an oncogene: a genotranscriptomic/proteomic meta-analysis. PMID:26561469
Gene Network Rewiring to Study Melanoma Stage Progression and Elements Essential for Driving Melanoma. PMID:26558755
Gene expression profile analysis of ventilator-associated pneumonia. PMID:26459786
Bioinformatics analyses of differentially expressed genes associated with bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma. PMID:26445550
How do oncoprotein mutations rewire protein-protein interaction networks? PMID:26325016
Identification of the key genes connected with plasma cells of multiple myeloma using expression profiles. PMID:26229487
Effects of β-catenin on differentially expressed genes in multiple myeloma. PMID:26223925
Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic. PMID:26046465
Molecular mechanisms for alcoholic hepatitis based on analysis of gene expression profile. PMID:26045708
Prediction of cancer proteins by integrating protein interaction, domain frequency, and domain interaction data using machine learning algorithms. PMID:25866773
Identification of stage-specific biomarkers in lung adenocarcinoma based on RNA-seq data. PMID:25861020
Transcription factor and microRNA-regulated network motifs for cancer and signal transduction networks. PMID:25707690
Crucial microRNAs and genes of human primary breast cancer explored by microRNA-mRNA integrated analysis. PMID:25680412
Identification of core miRNA based on small RNA-seq and RNA-seq for colorectal cancer by bioinformatics. PMID:25412953
The influence of mtDNA deletion on lung cancer cells under the conditions of hypoxia and irradiation. PMID:25218334
Modulation of age- and cancer-associated DNA methylation change in the healthy colon by aspirin and lifestyle. PMID:24973978
FRK inhibits migration and invasion of human glioma cells by promoting N-cadherin/β-catenin complex formation. PMID:24969324
Tags:
Tags
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cancer
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
gene
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
text mining
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
tumor
metasource: Fairsharing.org
version: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
human genes and diseases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
cancer gene databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Tags
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cancer
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
gene
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
text mining
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
tumor
metasource: Fairsharing.orgversion: FAIRsharing.org: TAG; Tumor Associated Gene database; DOI: https://doi.org/10.25504/FAIRsharing.znjr4p; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:08 p.m.
human genes and diseases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
cancer gene databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
cancer gene text mining tumor human genes and diseases cancer-related genes
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