COLOMBOS v2.0: An ever expanding collection of bacterial expression compendia

The COLOMBOS database (http://www.colombos.net) features comprehensive organism-specific cross-platform gene expression compendia of several bacterial model organisms and is supported by a fully interactive web portal and an extensive web API. COLOMBOS, name derived from the acronym 'COLections Of for Bacterial OrganismS', was originally published in PLoS One (1) and hosts several large expression compendia derived from high-throughput expression experiments with an explicit focus on bacterial organisms. The expression experiments available in COLOMBOS are derived from public resources, such as the Gene Expression Omnibus(2) or ArrayExpress(3) repositories, but the actual data originates from a reanalysis starting from the raw hybridization intensities for microarrays or short read sequences for RNA-seq using a consistent and robust normalization pipeline with stringent quality controls at each step. This procedure yields high quality expression compendia that can directly integrate high-throughput expression data from different technological platforms.

Webpage:
http://colombos.net/

Publications:

Tags:

microarray data and other gene expression

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