R33K90 last accessed: 2022-11-04

hmdb
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

Other names: HMDB, HMDB - The Human Metabolome Database, Human Metabolome Database, hmdb

The Human Metabolome Database (HMDB) is a database containing detailed information about small molecule metabolites found in the human body.It contains or links 1) chemical 2) clinical and 3) molecular biology/biochemistry data.

Webpage:

http://www.hmdb.ca

Licence:

Name: HMDB Attribution required
URL: https://hmdb.ca/citing

Publications:

Publications
More detailed information about this field from each metasource.

HMDB 3.0--The Human Metabolome Database in 2013
PMID: 23161693
metasource: Fairsharing.org
version: FAIRsharing.org: HMDB; The Human Metabolome Database; DOI: https://doi.org/10.25504/FAIRsharing.sye5js; Last edited: April 26, 2021, 3:27 p.m.; Last accessed: Jan 03 2022 7:08 p.m.

HMDB: the Human Metabolome Database
PMID: 17202168
metasource: Fairsharing.org
version: FAIRsharing.org: HMDB; The Human Metabolome Database; DOI: https://doi.org/10.25504/FAIRsharing.sye5js; Last edited: April 26, 2021, 3:27 p.m.; Last accessed: Jan 03 2022 7:08 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

HMDB: a knowledgebase for the human metabolome
PMID: 18953024
metasource: Fairsharing.org
version: FAIRsharing.org: HMDB; The Human Metabolome Database; DOI: https://doi.org/10.25504/FAIRsharing.sye5js; Last edited: April 26, 2021, 3:27 p.m.; Last accessed: Jan 03 2022 7:08 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

Metabolomics: the principles and potential applications to transplantation
PMID: 16302993
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

http://dx.doi.org/10.1093/nar/gks1065
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

HMDB 3.0--The Human Metabolome Database in 2013 PubMed citations: 1199.

1199 articles citing: HMDB 3.0--The Human Metabolome Database in 2013

Trans- and Multigenerational Maternal Social Isolation Stress Programs the Blood Plasma Metabolome in the F3 Generation. PMID:35888696
Combined Analysis of BSA-Seq Based Mapping, RNA-Seq, and Metabolomic Unraveled Candidate Genes Associated with Panicle Grain Number in Rice (Oryza sativa L.). PMID:35883474
Whole-body metabolic modelling predicts isoleucine dependency of SARS-CoV-2 replication. PMID:35874091
MetHoS: a platform for large-scale processing, storage and analysis of metabolomics data. PMID:35804309
Plasma metabolomic analysis indicates flavonoids and sorbic acid are associated with incident diabetes: A nested case-control study among Women's Interagency HIV Study participants. PMID:35802662
Identifying potential biomarkers and therapeutic targets for dogs with sepsis using metabolomics and lipidomics analyses. PMID:35802586
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions. PMID:35768426
Metabolomic and Transcriptomic Profiling Uncover the Underlying Mechanism of Color Differentiation in Scutellaria baicalensis Georgi. Flowers. PMID:35755689
Targeted gut microbiota manipulation attenuates seizures in a model of infantile spasms syndrome. PMID:35730569
Integration of Transcriptomics Data and Metabolomic Data Using Biomedical Literature Mining and Pathway Analysis. PMID:35713871
Addition of Prebiotics to the Ketogenic Diet Improves Metabolic Profile but Does Not Affect Seizures in a Rodent Model of Infantile Spasms Syndrome. PMID:35684010
NMR-Based Metabolomic Approach for Evaluation of the Harvesting Time and Cooking Characteristics of Different Cassava Genotypes. PMID:35681401
Effect of Supplementation on Levels of Homovanillic and Vanillylmandelic Acids in Children with Autism Spectrum Disorders. PMID:35629927
Transcriptome and metabolome profiling in different stages of infestation of Eucalyptus urophylla clones by Ralstonia solanacearum. PMID:35616707
Postprandial Responses on Serum Metabolome to Milk and Yogurt Intake in Young and Older Men. PMID:35600812
Metabolism and Endocrine Disorders: What Wnt Wrong? PMID:35600583
Chronic exposure to high-density polyethylene microplastic through feeding alters the nutrient metabolism of juvenile yellow perch (Perca flavescens). PMID:35573095
Metabolomic Profiling of Plasma Reveals Differential Disease Severity Markers in COVID-19 Patients. PMID:35572676
Discriminant Analysis of the Nutritional Components between Organic Eggs and Conventional Eggs: A 1H NMR-Based Metabolomics Study. PMID:35566355
Integrative Analysis of Metabolomics and Transcriptomics Reveals Molecular Mechanisms of Anthocyanin Metabolism in the Zikui Tea Plant (Camellia sinensis cv. Zikui). PMID:35563169
A non-invasive approach to explore the discriminatory potential of the urinary volatilome of invasive ductal carcinoma of the breast. PMID:35542123
Metabolic profiling putatively identifies plasma biomarkers of male infertility using UPLC-ESI-IT-TOFMS. PMID:35541937
Exploring the biomarkers and therapeutic mechanism of kidney-yang deficiency syndrome treated by You-gui pill using systems pharmacology and serum metabonomics. PMID:35539000
The N-Terminus of Human Sulfotransferase 2B1b─a Sterol-Sensing Allosteric Site. PMID:35523209
A metabolomic study for chronic heart failure patients based on a dried blood spot mass spectrometry approach. PMID:35515477
The exposome paradigm to predict environmental health in terms of systemic homeostasis and resource balance based on NMR data science. PMID:35480260
Multiplatform Metabolomics Studies of Human Cancers With NMR and Mass Spectrometry Imaging. PMID:35463966
The Potential Antipyretic Mechanism of Ellagic Acid with Brain Metabolomics Using Rats with Yeast-Induced Fever. PMID:35458665
Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice. PMID:35448524
Comparison of Microbial Community and Metabolites in Four Stomach Compartments of Myostatin-Gene-Edited and Non-edited Cattle. PMID:35401485
Heart Failure and Drug Therapies: A Metabolic Review. PMID:35328390
Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines. PMID:35315332
Detection of the Disorders of Glycerophospholipids and Amino Acids Metabolism in Lung Tissue From Male COPD Patients. PMID:35309511
Identification of neurodegeneration indicators and disease progression in metachromatic leukodystrophy using quantitative NMR-based urinary metabolomics. PMID:35281658
Pharmacophore-Based Discovery of Substrates of a Novel Drug/Proton-Antiporter in the Human Brain Endothelial hCMEC/D3 Cell Line. PMID:35213988
The Potential of Metabolomics in Biomedical Applications. PMID:35208267
Comprehensive Peak Characterization (CPC) in Untargeted LC-MS Analysis. PMID:35208212
Postmortem Metabolomics Reveal Acylcarnitines as Potential Biomarkers for Fatal Oxycodone-Related Intoxication. PMID:35208184
Early Time-Restricted Feeding Amends Circadian Clock Function and Improves Metabolic Health in Male and Female Nile Grass Rats. PMID:35200758
Acute aerobic exercise reveals that FAHFAs distinguish the metabolomes of overweight and normal-weight runners. PMID:35192550
Identifying the Metabolic Signatures of PPARD-Overexpressing Gastric Tumors. PMID:35163565
Serum Metabolic Fingerprints on Bowl-Shaped Submicroreactor Chip for Chemotherapy Monitoring. PMID:35099942
Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms. PMID:35090836
Experimental determination of Escherichia coli biomass composition for constraint-based metabolic modeling. PMID:35085271
Targeting Colorectal Cancer Cells with a Functionalised Calix[4]arene Receptor: Biophysical Studies. PMID:35056825
Myostatin Knockout Regulates Bile Acid Metabolism by Promoting Bile Acid Synthesis in Cattle. PMID:35049827
Metabolomic Alteration in the Plasma of Wild Rodents Environmentally Exposed to Lead: A Preliminary Study. PMID:35010801
Gut Microbiota as a Source of Uremic Toxins. PMID:35008909
HMDB 5.0: the Human Metabolome Database for 2022. PMID:34986597
Tumor microenvironment metabolites directing T cell differentiation and function. PMID:34973923
Mass-Spectrometry-Based Functional Proteomic and Phosphoproteomic Technologies and Their Application for Analyzing Ex Vivo and In Vitro Models of Hypertrophic Cardiomyopathy. PMID:34948439
7-Ketocholesterol Induces Lipid Metabolic Reprogramming and Enhances Cholesterol Ester Accumulation in Cardiac Cells. PMID:34944104
Fully Automated Quantitative Measurement of Serum Organic Acids via LC-MS/MS for the Diagnosis of Organic Acidemias: Establishment of an Automation System and a Proof-of-Concept Validation. PMID:34943431
A Metabolomics Approach to Increasing Chinese Hamster Ovary (CHO) Cell Productivity. PMID:34940581
Diel investments in metabolite production and consumption in a model microbial system. PMID:34921302
Recent Metabolomics Analysis in Tumor Metabolism Reprogramming. PMID:34901157
Transcriptomic and metabolomic changes triggered by Macrosiphum rosivorum in rose (Rosa longicuspis). PMID:34886808
UPLC-MS/MS and Network Pharmacology-Based Analysis of Bioactive Anti-Depression Compounds in Betel Nut. PMID:34880597
A Network Pharmacology-Based Study on Irritable Bowel Syndrome Prevention and Treatment Utilizing Shenling Baizhu Powder. PMID:34859100
Mining Anti-Inflammation Molecules From Nippostrongylus brasiliensis-Derived Products Through the Metabolomics Approach. PMID:34858883
A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation. PMID:34858137
Bacterial challenge-associated metabolic phenotypes in Hermetia illucens defining nutritional and functional benefits. PMID:34857836
Mild Muscle Mitochondrial Fusion Distress Extends Drosophila Lifespan through an Early and Systemic Metabolome Reorganization. PMID:34830014
Metabolomic and lipidomic characterization of an X-chromosome deletion disorder in neural progenitor cells by UHPLC-HRMS. PMID:34820667
Metabolic profile changes in serum of migraine patients detected using 1H-NMR spectroscopy. PMID:34819016
Foodomics: Analytical Opportunities and Challenges. PMID:34813295
A Single Human-Relevant Fast Food Meal Rapidly Reorganizes Metabolomic and Transcriptomic Signatures in a Gut Microbiota-Dependent Manner. PMID:34804604
A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria. PMID:34799606
Metabolomic diferences between COVID-19 and H1N1 influenza induced ARDS. PMID:34781986
Metabolite Identification Using Infrared Ion Spectroscopy─Novel Biomarkers for Pyridoxine-Dependent Epilepsy. PMID:34756024
Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice. PMID:34707105
Secondary Metabolism and Hormone Response Reveal the Molecular Mechanism of Triploid Mulberry (Morus Alba L.) Trees Against Drought. PMID:34691101
Pharmacometabolomics by NMR in Oncology: A Systematic Review. PMID:34681239
Integrative Metabolomics Reveals Deep Tissue and Systemic Metabolic Remodeling in Glioblastoma. PMID:34680306
Lipid Profiling in Cancer Diagnosis with Hand-Held Ambient Mass Spectrometry Probes: Addressing the Late-Stage Performance Concerns. PMID:34677375
Untargeted plasma metabolomics identifies broad metabolic perturbations in glycogen storage disease type I. PMID:34671989
Longitudinal Multi-Omics Study of a Mother-Infant Dyad from Breastfeeding to Weaning: An Individualized Approach to Understand the Interactions Among Diet, Fecal Metabolome and Microbiota Composition. PMID:34671642
Dynamic Transcriptomic and Metabolomic Analyses of Madhuca pasquieri (Dubard) H. J. Lam During the Post-germination Stages. PMID:34659296
Direct on-swab metabolic profiling of vaginal microbiome host interactions during pregnancy and preterm birth. PMID:34645809
Changes in serum and urinary metabolomic profile after a dietary intervention in patients with irritable bowel syndrome. PMID:34634050
Liquid Chromatography-Mass Spectrometry for Clinical Metabolomics: An Overview. PMID:34628633
Automated metabolic assignment: Semi-supervised learning in metabolic analysis employing two dimensional Nuclear Magnetic Resonance (NMR). PMID:34589182
Branched-Chain Amino Acids and Risk of Breast Cancer. PMID:34585062
Metabolomics Analysis of Amniotic Fluid in Euploid Foetuses with Thickened Nuchal Translucency by Gas Chromatography-Mass Spectrometry. PMID:34575062
Lipid Metabolite Biomarkers in Cardiovascular Disease: Discovery and Biomechanism Translation from Human Studies. PMID:34564437
Transcriptome and Metabolome Analyses of the Flowers and Leaves of Chrysanthemum dichrum. PMID:34531898
Food Composition Databases: Does It Matter to Human Health? PMID:34444976
Profiling Analysis of Volatile and Non-volatile Compounds in Vitis Vinifera Berries (cv. Chardonnay) and Spontaneous Bud Mutation. PMID:34422886
A Warburg-like metabolic program coordinates Wnt, AMPK, and mTOR signaling pathways in epileptogenesis. PMID:34358226
Serum Metabolomic Analysis Suggests Impairment of Myocardial Energy Production in Takotsubo Syndrome. PMID:34357333
Serum Metabolic Disturbances Associated with Acute-on-chronic Liver Failure in Patients with Underlying Alcoholic Liver Diseases: An Elaborative NMR-based Metabolomics Study. PMID:34349490
Impact of Weaning and Maternal Immune Activation on the Metabolism of Pigs. PMID:34336923
Analysis of Bioactive Components in the Fruit, Roots, and Leaves of Alpinia oxyphylla by UPLC-MS/MS. PMID:34335828
Proteomics, Lipidomics, Metabolomics, and 16S DNA Sequencing of Dental Plaque From Patients With Diabetes and Periodontal Disease. PMID:34332123
Single Quadrupole Multiple Fragment Ion Monitoring Quantitative Mass Spectrometry. PMID:34313111
DNAJA1 Dysregulates Metabolism Promoting an Antiapoptotic Phenotype in Pancreatic Ductal Adenocarcinoma. PMID:34264680
Paired maternal and fetal metabolomics reveal a differential fingerprint in preeclampsia versus fetal growth restriction. PMID:34257400
What We Know So Far about the Metabolite-Mediated Microbiota-Intestinal Immunity Dialogue and How to Hear the Sound of This Crosstalk. PMID:34205653
Unraveling the Regulatory Mechanism of Color Diversity in Camellia japonica Petals by Integrative Transcriptome and Metabolome Analysis. PMID:34178004
Metabolomic Profiling Demonstrates Postprandial Changes in Fatty Acids and Glycerophospholipids Are Associated with Fasting Inflammation in Guatemalan Adults. PMID:34113999
Urine metabolite profiling of Indian Antarctic Expedition members: NMR spectroscopy-based metabolomic investigation. PMID:34113732
Application of Volatilome Analysis to the Diagnosis of Mycobacteria Infection in Livestock. PMID:34109231
Comparative analysis of tuberous root metabolites between cultivated and wild varieties of Rehmannia glutinosa by widely targeted metabolomics. PMID:34075137
Metabolomic Analysis Evidences That Uterine Epithelial Cells Enhance Blastocyst Development in a Microfluidic Device. PMID:34068340
Automated Sequential Analysis of Hydrophilic and Lipophilic Fractions of Biological Samples: Increasing Single-Injection Chemical Coverage in Untargeted Metabolomics. PMID:34063084
Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions. PMID:34043632
The Effects of Sampling and Storage Conditions on the Metabolite Profile of the Marine Sponge Geodia barretti. PMID:34041223
Transcriptomic and metabolomic joint analysis reveals distinct flavonoid biosynthesis regulation for variegated testa color development in peanut (Arachis hypogaea L.). PMID:34021210
RcTGA1 and glucosinolate biosynthesis pathway involvement in the defence of rose against the necrotrophic fungus Botrytis cinerea. PMID:34001006
Evaluation of potential metabolomic-based biomarkers of protein, carbohydrate and fat intakes using a controlled feeding study. PMID:33991228
Metabolomics in cancer research and emerging applications in clinical oncology. PMID:33982817
NMR analysis of the correlation of metabolic changes in blood and cerebrospinal fluid in Alzheimer model male and female mice. PMID:33970919
Kidney Diseases: The Age of Molecular Markers. PMID:33959903
Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI. PMID:33948567
Quo Vadis Caenorhabditis elegans Metabolomics-A Review of Current Methods and Applications to Explore Metabolism in the Nematode. PMID:33947148
Precision Oncology via NMR-Based Metabolomics: A Review on Breast Cancer. PMID:33925233
Fecal Metabolic Profiling of Breast Cancer Patients during Neoadjuvant Chemotherapy Reveals Potential Biomarkers. PMID:33919750
Drug repurposing for cancer treatment through global propagation with a greedy algorithm in a multilayer network. PMID:33893730
A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases. PMID:33883556
NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. PMID:33843271
Gaussian graphical modeling of the serum exposome and metabolome reveals interactions between environmental chemicals and endogenous metabolites. PMID:33828161
The Importance of Objective Stool Classification in Fecal 1H-NMR Metabolomics: Exponential Increase in Stool Crosslinking Is Mirrored in Systemic Inflammation and Associated to Fecal Acetate and Methionine. PMID:33809780
SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome. PMID:33807773
Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors. PMID:33803907
Effects of Low Dose Space Radiation Exposures on the Splenic Metabolome. PMID:33802822
Benchmarking Non-Targeted Metabolomics Using Yeast-Derived Libraries. PMID:33802096
Prolyl Hydroxylase 3 Knockdown Accelerates VHL-Mutant Kidney Cancer Growth In Vivo. PMID:33799686
Dynamic Bayesian Networks for Integrating Multi-omics Time Series Microbiome Data. PMID:33785573
Effects of Clostridium butyricum on growth performance, metabonomics and intestinal microbial differences of weaned piglets. PMID:33752593
Rewiring of purine metabolism in response to acidosis stress in glioma stem cells. PMID:33723244
Systems-wide effects of short-term feed deprivation in obese mice. PMID:33707503
Metabolites and metabolic pathways associated with glucocorticoid resistance in pregnant African-American women. PMID:33693436
Empowering large chemical knowledge bases for exposomics: PubChemLite meets MetFrag. PMID:33685519
Ranking Metabolite Sets by Their Activity Levels. PMID:33670102
Comprehensive Evaluation of Metabolites and Minerals in 6 Microgreen Species and the Influence of Maturity. PMID:33644632
Megasphaera lornae sp. nov., Megasphaera hutchinsoni sp. nov., and Megasphaera vaginalis sp. nov.: novel bacteria isolated from the female genital tract. PMID:33616513
Serum Metabolomics Study of Papillary Thyroid Carcinoma Based on HPLC-Q-TOF-MS/MS. PMID:33598460
Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. PMID:33574263
ChemSpectra: a web-based spectra editor for analytical data. PMID:33568182
Metabolic dysfunction in pregnancy: Fingerprinting the maternal metabolome using proton nuclear magnetic resonance spectroscopy. PMID:33532625
Integration of metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction. PMID:33522389
Differences between infected and noninfected synovial fluid. PMID:33502243
A Nuclear Magnetic Resonance-Based Metabolomic Study to Identify Metabolite Differences between Iranian Isolates of Leishmania major and Leishmania tropica. PMID:33487791
A dynamic multi-tissue model to study human metabolism. PMID:33483512
An Ion Chromatography-Ultrahigh-Resolution-MS1/Data-Independent High-Resolution MS2 Method for Stable Isotope-Resolved Metabolomics Reconstruction of Central Metabolic Networks. PMID:33482055
Muscle metabolic remodelling patterns in Duchenne muscular dystrophy revealed by ultra-high-resolution mass spectrometry imaging. PMID:33479270
HastaLaVista, a web-based user interface for NMR-based untargeted metabolic profiling analysis in biomedical sciences: towards a new publication standard. PMID:33430999
MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor-1. PMID:33416496
Creation and filtering of a recurrent spectral library of CHO cell metabolites and media components. PMID:33404064
Single cell metabolomics using mass spectrometry: Techniques and data analysis. PMID:33384110
Discovery and validation of an NMR-based metabolomic profile in urine as TB biomarker. PMID:33339845
Functional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming. PMID:33330447
Identification and quantification of honeybee venom constituents by multiplatform metabolomics. PMID:33303913
Targeting Mitochondrial Complex I Overcomes Chemoresistance in High OXPHOS Pancreatic Cancer. PMID:33294863
Metabolomics: The Stethoscope for the Twenty-First Century. PMID:33271569
Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts. PMID:33268560
Mapping choline metabolites in normal and transformed cells. PMID:33249526
Widely Targeted UHPLC-MS/MS Metabolomic Analysis on the Chemical Variation in Blueberry-Filled Pastries During Processing. PMID:33240917
Network Analysis of Gut Microbiome and Metabolome to Discover Microbiota-Linked Biomarkers in Patients Affected by Non-Small Cell Lung Cancer. PMID:33227982
Alterations of Gut Microbiome and Metabolite Profiling in Mice Infected by Schistosoma japonicum. PMID:33162984
Soluble Immune Checkpoints, Gut Metabolites and Performance Status as Parameters of Response to Nivolumab Treatment in NSCLC Patients. PMID:33158018
Metabolite signatures of diverse Camellia sinensis tea populations. PMID:33149146
Microbiota-Derived Short-Chain Fatty Acids Promote LAMTOR2-Mediated Immune Responses in Macrophages. PMID:33144310
Characteristic of Metabolic Status in Heart Failure and Its Impact in Outcome Perspective. PMID:33138215
Metabolomic Profiling After a Meal Shows Greater Changes and Lower Metabolic Flexibility in Cardiometabolic Diseases. PMID:33134764
Immunometabolic Interplay in the Tumor Microenvironment. PMID:33125860
Metabolomics analysis reveals Embden Meyerhof Parnas pathway activation and flavonoids accumulation during dormancy transition in tree peony. PMID:33096979
Postmortomics: The Potential of Untargeted Metabolomics to Highlight Markers for Time Since Death. PMID:33095683
NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition. PMID:33092571
Transcriptome and metabolite profiling reveals the effects of Funneliformis mosseae on the roots of continuously cropped soybeans. PMID:33087042
Untargeted metabolic profiling in dried blood spots identifies disease fingerprint for pyruvate kinase deficiency. PMID:33054133
NMR-Based Metabolomic Analysis and Microbial Composition of Soil Supporting Burkea africana Growth. PMID:33050369
Altered metabolomic profiling of overweight and obese adolescents after combined training is associated with reduced insulin resistance. PMID:33037261
Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites. PMID:33033375
Mapping metabolic oscillations during cell cycle progression. PMID:33016215
Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas. PMID:32993063
Laser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening. PMID:32980699
Metabolic Response in Patients With Post-treatment Lyme Disease Symptoms/Syndrome. PMID:32975577
Preanalytical Sample Handling Conditions and Their Effects on the Human Serum Metabolome in Epidemiologic Studies. PMID:32959873
Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti. PMID:32948809
Metabolic Profiling of a Porcine Combat Trauma-Injury Model Using NMR and Multi-Mode LC-MS Metabolomics-A Preliminary Study. PMID:32948079
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis. PMID:32937194
Transcriptome and Flavonoids Metabolomic Analysis Identifies Regulatory Networks and Hub Genes in Black and White Fruits of Lycium ruthenicum Murray. PMID:32922426
Effects of time and temperature during melanging on the volatile profile of dark chocolate. PMID:32913253
3,3'-Dichlorobiphenyl Is Metabolized to a Complex Mixture of Oxidative Metabolites, Including Novel Methoxylated Metabolites, by HepG2 Cells. PMID:32910851
Analysis of Flavonoid Metabolites in Chaenomeles Petals Using UPLC-ESI-MS/MS. PMID:32887276
Food Phenotyping: Recording and Processing of Non-Targeted Liquid Chromatography Mass Spectrometry Data for Verifying Food Authenticity. PMID:32878155
Plasma metabolomic study in perinatally HIV-infected children using 1H NMR spectroscopy reveals perturbed metabolites that sustain during therapy. PMID:32866201
Alterations in the Gut Microbiome and Cecal Metabolome During Klebsiella pneumoniae-Induced Pneumosepsis. PMID:32849494
Tracking the carbons supplying gluconeogenesis. PMID:32817317
Hyperoxia affects the lung tissue: A porcine histopathological and metabolite study using five hours of apneic oxygenation. PMID:32812938
Metabolomics in Radiation Biodosimetry: Current Approaches and Advances. PMID:32796693
CoMNRank: An integrated approach to extract and prioritize human microbial metabolites from MEDLINE records. PMID:32791237
Comparative Metabolomic Analysis of Dendrobium officinale under Different Cultivation Substrates. PMID:32785071
Excretory/Secretory Metabolome of the Zoonotic Roundworm Parasite Toxocara canis. PMID:32781793
Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway. PMID:32774853
Air Pollution and Adverse Pregnancy and Birth Outcomes: Mediation Analysis Using Metabolomic Profiles. PMID:32770318
Biochemical Assessments of Seminal Plasma Zinc, Testis-Expressed Sequence 101 and Free Amino Acids and Their Correlations with Reproductive Hormones in Male Infertility. PMID:32767245
A Novel Network Pharmacology Strategy to Decode Metabolic Biomarkers and Targets Interactions for Depression. PMID:32760300
Metabolic response of blood vessels to TNFα. PMID:32749215
Exercise Induced Changes in Salivary and Serum Metabolome in Trained Standardbred, Assessed by 1H-NMR. PMID:32708237
Antigen Retrieval and Its Effect on the MALDI-MSI of Lipids in Formalin-Fixed Paraffin-Embedded Tissue. PMID:32678590
A quest to identify suitable organic tracers for estimating children's dust ingestion rates. PMID:32661335
Novel Metabolomics Serum Biomarkers for Pancreatic Ductal Adenocarcinoma by the Comparison of Pre-, Postoperative and Normal Samples. PMID:32626510
MCR-ALS analysis of 1H NMR spectra by segments to study the zebrafish exposure to acrylamide. PMID:32617759
Longitudinal wastewater sampling in buildings reveals temporal dynamics of metabolites. PMID:32598361
Macronutrient, Energy, and Bile Acid Metabolism Pathways Altered Following a Physiological Meal Challenge, Relative to Fasting, among Guatemalan Adults. PMID:32597983
Plasma metabolome and cognitive skills in Down syndrome. PMID:32591596
Automatic extraction, prioritization and analysis of gut microbial metabolites from biomedical literature. PMID:32561832
In Vitro Fermentation of Sheep and Cow Milk Using Infant Fecal Bacteria. PMID:32560419
Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis. PMID:32539684
Phosphorus NMR and Its Application to Metabolomics. PMID:32530272
NMR and MS-based Stable Isotope-Resolved Metabolomics and Applications in Cancer Metabolism. PMID:32523238
The Bovine Metabolome. PMID:32517015
Metabolic alterations caused by the mutation and overexpression of the Tmem135 gene. PMID:32515224
Applications of Chromatography-Ultra High-Resolution MS for Stable Isotope-Resolved Metabolomics (SIRM) Reconstruction of Metabolic Networks. PMID:32483395
A Translational In Vivo and In Vitro Metabolomic Study Reveals Altered Metabolic Pathways in Red Blood Cells of Type 2 Diabetes. PMID:32471219
Personalized whole-body models integrate metabolism, physiology, and the gut microbiome. PMID:32463598
Metabolomics window into the role of acute kidney injury after coronary artery bypass grafting in diabetic nephropathy progression. PMID:32461830
Cross-Omics: Integrating Genomics with Metabolomics in Clinical Diagnostics. PMID:32443577
Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease. PMID:32442208
Can joint fluid metabolic profiling (or "metabonomics") reveal biomarkers for osteoarthritis and inflammatory joint disease?: A systematic review. PMID:32435463
Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-based Bioprocesses. PMID:32429145
Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice. PMID:32421118
A single administration of the antibiotic, minocycline, reduces fear processing and improves implicit learning in healthy volunteers: analysis of the serum metabolome. PMID:32404908
Pathway-Activity Likelihood Analysis and Metabolite Annotation for Untargeted Metabolomics Using Probabilistic Modeling. PMID:32375258
Characterization of cold stress responses in different rapeseed ecotypes based on metabolomics and transcriptomics analyses. PMID:32266113
"notame": Workflow for Non-Targeted LC-MS Metabolic Profiling. PMID:32244411
Altered composition and functional profile of high-density lipoprotein in leprosy patients. PMID:32226013
Metabolic reprogramming in tumors: Contributions of the tumor microenvironment. PMID:32215288
Deriving Lipid Classification Based on Molecular Formulas. PMID:32214009
Metabolomics of sleep disorders in HIV: a narrative review. PMID:32198720
A Solution to Antifolate Resistance in Group B Streptococcus: Untargeted Metabolomics Identifies Human Milk Oligosaccharide-Induced Perturbations That Result in Potentiation of Trimethoprim. PMID:32184236
Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites. PMID:32160915
Metabolome Analysis Identified Okaramines in the Soybean Rhizosphere as a Legacy of Hairy Vetch. PMID:32153648
Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study. PMID:32148965
Analysis and Simulation of Glioblastoma Cell Lines-Derived Extracellular Vesicles Metabolome. PMID:32131411
Classification of Flavonoid Metabolomes via Data Mining and Quantification of Hydroxyl NMR Signals. PMID:32108467
A Metabolomic Investigation of the Effect of Eosin B on Game-tocyte of Plasmodium falciparum Using 1HNMR Spectroscopy. PMID:32099562
Higher Levels of Low Molecular Weight Sulfur Compounds and Homocysteine Thiolactone in the Urine of Autistic Children. PMID:32098164
Metabolic Reprogramming of Host Cells in Response to Enteroviral Infection. PMID:32085644
A salivary metabolite signature that reflects gingival host-microbe interactions: instability predicts gingivitis susceptibility. PMID:32080300
Vanillin and vanillic acid modulate antioxidant defense system via amelioration of metabolic complications linked to Fe2+-induced brain tissues damage. PMID:32065337
Urine Metabolite Profiles and Nutrient Intake Based on 4-Day Weighed Food Diary in Habitual Vegans, Vegetarians, and Omnivores. PMID:32047921
Plasma lipid profile associates with the improvement of psychological well-being in individuals with perceived stress symptoms. PMID:32034255
Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis. PMID:32025330
Characterisation of the Serum Metabolic Signature of Cholangiocarcinoma in a United Kingdom Cohort. PMID:32025163
Untargeted Metabolomics for Metabolic Diagnostic Screening with Automated Data Interpretation Using a Knowledge-Based Algorithm. PMID:32024143
Gut metabolomics profiling of non-small cell lung cancer (NSCLC) patients under immunotherapy treatment. PMID:32014010
Predicting octanol/water partition coefficients for the SAMPL6 challenge using the SM12, SM8, and SMD solvation models. PMID:32002781
Absence of the Caspases 1/11 Modulates Liver Global Lipid Profile and Gut Microbiota in High-Fat-Diet-Induced Obese Mice. PMID:31998283
A serum metabolomics study of patients with nAMD in response to anti-VEGF therapy. PMID:31992792
Integrative Metabolic Pathway Analysis Reveals Novel Therapeutic Targets in Osteoarthritis. PMID:31980557
Activated corticosterone synthetic pathway is involved in poor responses to re-oxygenation after prolonged hypoxia. PMID:31966693
Sangiovese cv Pomace Seeds Extract-Fortified Kefir Exerts Anti-Inflammatory Activity in an In Vitro Model of Intestinal Epithelium Using Caco-2 Cells. PMID:31936207
Expression of FXR and HRG and their clinicopathological significance in benign and malignant pancreatic lesions. PMID:31934033
DESI-MSI and METASPACE indicates lipid abnormalities and altered mitochondrial membrane components in diabetic renal proximal tubules. PMID:31925564
Direct Implementation of Intestinal Permeability Test in NMR Metabolomics for Simultaneous Biomarker Discovery-A Feasibility Study in a Preterm Piglet Model. PMID:31906404
Differential Network Analysis Reveals Metabolic Determinants Associated with Mortality in Acute Myocardial Infarction Patients and Suggests Potential Mechanisms Underlying Different Clinical Scores Used To Predict Death. PMID:31899863
DHA-Induced Perturbation of Human Serum Metabolome. Role of the Food Matrix and Co-Administration of Oat β-glucan and Anthocyanins. PMID:31892215
Characterisation of the Urinary Metabolic Profile of Liver Fluke-Associated Cholangiocarcinoma. PMID:31889746
A Perspective and Framework for Developing Sample Type Specific Databases for LC/MS-Based Clinical Metabolomics. PMID:31877765
Relationship between gut microbiota and circulating metabolites in population-based cohorts. PMID:31862950
Metabolomics of Small Intestine Neuroendocrine Tumors and Related Hepatic Metastases. PMID:31835679
Metabolic reprogramming of Salmonella infected macrophages and its modulation by iron availability and the mTOR pathway. PMID:31832425
High-resolution metabolomic profiling of Alzheimer's disease in plasma. PMID:31828981
Host Metabolic Response in Early Lyme Disease. PMID:31821002
Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine. PMID:31815377
Untargeted Metabolomics-Based Screening Method for Inborn Errors of Metabolism using Semi-Automatic Sample Preparation with an UHPLC- Orbitrap-MS Platform. PMID:31779119
A comparative metabolomics analysis of the components of heartwood and sapwood in Taxus chinensis (Pilger) Rehd. PMID:31776382
An Integrated Analysis of the Rice Transcriptome and Metabolome Reveals Root Growth Regulation Mechanisms in Response to Nitrogen Availability. PMID:31771277
Analytical considerations for postmortem metabolomics using GC-high-resolution MS. PMID:31758199
Identifying novel sphingosine kinase 1 inhibitors as therapeutics against breast cancer. PMID:31752564
Global metabolite profiles of rice brown planthopper-resistant traits reveal potential secondary metabolites for both constitutive and inducible defenses. PMID:31741127
Prediction of disease-related metabolites using bi-random walks. PMID:31730648
The plasma metabolome of women in early pregnancy differs from that of non-pregnant women. PMID:31726468
Untargeted Urinary 1H NMR-Based Metabolomic Pattern as a Potential Platform in Breast Cancer Detection. PMID:31703396
Metabolomic studies of Pseudomonas aeruginosa. PMID:31701321
Mass Spectrometry: A Guide for the Clinician. PMID:31695250
Metabolomic Analysis of Influenza A Virus A/WSN/1933 (H1N1) Infected A549 Cells during First Cycle of Viral Replication. PMID:31683654
Influence of Drying Method on NMR-Based Metabolic Profiling of Human Cell Lines. PMID:31683565
LC-MS based metabolomic profiling for renal cell carcinoma histologic subtypes. PMID:31666664
Classifying the antibody-negative NMO syndromes: Clinical, imaging, and metabolomic modeling. PMID:31659123
Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics. PMID:31640247
ncRNA2MetS: a manually curated database for non-coding RNAs associated with metabolic syndrome. PMID:31637139
Assessing the Pre-Analytical Stability of Small-Molecule Metabolites in Cerebrospinal Fluid Using Direct-Infusion Metabolomics. PMID:31635433
Metabolic Profiling and Compound-Class Identification Reveal Alterations in Serum Triglyceride Levels in Mice Immunized with Human Vaccine Adjuvant Alum. PMID:31625748
The Rise of Physiologic Media. PMID:31623927
Metandem: An online software tool for mass spectrometry-based isobaric labeling metabolomics. PMID:31623721
Metabolomic Perspectives in Antiblastic Cardiotoxicity and Cardioprotection. PMID:31590338
An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs. PMID:31587113
Monosodium Glutamate (MSG) Renders Alkalinizing Properties and Its Urinary Metabolic Markers of MSG Consumption in Rats. PMID:31569818
Metabolic profiles of serum samples from ground glass opacity represent potential diagnostic biomarkers for lung cancer. PMID:31555521
Untargeted Metabolomics for Autism Spectrum Disorders: Current Status and Future Directions. PMID:31551836
The metaRbolomics Toolbox in Bioconductor and beyond. PMID:31548506
Metabolomics and microbial composition increase insight into the impact of dietary differences in cirrhosis. PMID:31544308
Uncovering sperm metabolome to discover biomarkers for bull fertility. PMID:31533629
R-MetaboList 2: A Flexible Tool for Metabolite Annotation from High-Resolution Data-Independent Acquisition Mass Spectrometry Analysis. PMID:31533242
Redesigning the T-probe for mass spectrometry analysis of online lysis of non-adherent single cells. PMID:31519234
ADAPTIVE: leArning DAta-dePendenT, concIse molecular VEctors for fast, accurate metabolite identification from tandem mass spectra. PMID:31510641
Metabolic modulations of Pseudomonas graminis in response to H2O2 in cloud water. PMID:31488860
Tools for Enhanced NMR-Based Metabolomics Analysis. PMID:31463858
NMR Metabolomics Protocols for Drug Discovery. PMID:31463851
LAS: A Lipid Annotation Service Capable of Explaining the Annotations It Generates. PMID:31462967
Screening of Microbial Volatile Organic Compounds for Detection of Disease in Cattle: Development of Lab-scale Method. PMID:31431630
Ferulic Acid Modulates Dysfunctional Metabolic Pathways and Purinergic Activities, While Stalling Redox Imbalance and Cholinergic Activities in Oxidative Brain Injury. PMID:31422569
Stoichiometric gene-to-reaction associations enhance model-driven analysis performance: Metabolic response to chronic exposure to Aldrin in prostate cancer. PMID:31416420
Untargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models. PMID:31398922
Crystal structure of zymonic acid and a redetermination of its precursor, pyruvic acid. PMID:31391982
Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia. PMID:31387889
Salivary Metabolomics of Total Body Irradiated Nonhuman Primates Reveals Long-Term Normal Tissue Responses to Radiation. PMID:31352081
Lipid remodeling regulator 1 (LRL1) is differently involved in the phosphorus-depletion response from PSR1 in Chlamydomonas reinhardtii. PMID:31350858
Transcriptome analysis of acerola fruit ripening: insights into ascorbate, ethylene, respiration, and softening metabolisms. PMID:31338671
De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues. PMID:31337706
Nuclear magnetic resonance-based metabolomics and metabolic pathway networks from patient-matched esophageal carcinoma, adjacent noncancerous tissues and urine. PMID:31333313
Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy. PMID:31323682
Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne. PMID:31310630
Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia. PMID:31292453
Comprehensive Metabolomic Analysis of IDH1R132H Clinical Glioma Samples Reveals Suppression of β-oxidation Due to Carnitine Deficiency. PMID:31278288
Metabolome signature of autism in the human prefrontal cortex. PMID:31263778
PerMM: A Web Tool and Database for Analysis of Passive Membrane Permeability and Translocation Pathways of Bioactive Molecules. PMID:31259547
Metabolomic profiling of the excretory-secretory products of hookworm and whipworm. PMID:31254203
Metabolomic profiling suggests systemic signatures of premature aging induced by Hutchinson-Gilford progeria syndrome. PMID:31254107
NMR Spectroscopy for Metabolomics Research. PMID:31252628
Metabolic Effect of Dietary Taurine Supplementation on Grouper (Epinephelus coioides): A 1H-NMR-Based Metabolomics Study. PMID:31212947
Effects of saccharicterpenin on antioxidant status and urinary metabolic profile of rats. PMID:31193876
Antibiotic Exposure Has Sex-Dependent Effects on the Gut Microbiota and Metabolism of Short-Chain Fatty Acids and Amino Acids in Mice. PMID:31164448
Serum metabolite profiles of habitual diet: evaluation by 1H-nuclear magnetic resonance analysis. PMID:31127814
Metabolomics Analyses from Tissues in Parkinson's Disease. PMID:31127560
Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom population. PMID:31118840
13C Labeling of Nematode Worms to Improve Metabolome Coverage by Heteronuclear Nuclear Magnetic Resonance Experiments. PMID:31106208
Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease. PMID:31102408
Metabolomics Analysis in Serum from Patients with Colorectal Polyp and Colorectal Cancer by 1H-NMR Spectrometry. PMID:31089393
An Integrated Analysis of the Rice Transcriptome and Metabolome Reveals Differential Regulation of Carbon and Nitrogen Metabolism in Response to Nitrogen Availability. PMID:31083591
Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle. PMID:31080489
Evaluating sub-lethal stress from Roundup® exposure in Artemia franciscana using 1H NMR and GC-MS. PMID:31077969
Phospholipid levels in blood during community-acquired pneumonia. PMID:31063483
Metabolomics of Male Infertility: A New Tool for Diagnostic Tests. PMID:31058049
Gestational route to healthy birth (GaRBH): protocol for an Indian prospective cohort study. PMID:31048433
Characterizing novel olfactory receptors expressed in the murine renal cortex. PMID:31042061
An integrated genomic and metabolomic approach for defining survival time in adult oligodendrogliomas patients. PMID:31037432
Navigating in vitro bioactivity data by investigating available resources using model compounds. PMID:31036807
Use of faecal volatile organic compound analysis for ante-mortem discrimination between CWD-positive, -negative exposed, and -known negative white-tailed deer (Odocoileus virginianus). PMID:31032718
Microdialysis Workflow for Metabotyping Superficial Pathologies: Application to Burn Injury. PMID:31021084
Reverting Metabolic Dysfunction in Cortex and Cerebellum of APP/PS1 Mice, a Model for Alzheimer's Disease by Pioglitazone, a Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Agonist. PMID:31016475
Characterization of Tapeworm Metabolites and Their Reported Biological Activities. PMID:30991712
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production. PMID:30982734
Integrating a generalized data analysis workflow with the Single-probe mass spectrometry experiment for single cell metabolomics. PMID:30982520
Rapid Solution-Phase Hydrogen/Deuterium Exchange for Metabolite Compound Identification. PMID:30980382
Evaluation of an untargeted nano-liquid chromatography-mass spectrometry approach to expand coverage of low molecular weight dissolved organic matter in Arctic soil. PMID:30967565
Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population. PMID:30939782
The GC-MS metabolomics signature in patients with fibromyalgia syndrome directs to dysbiosis as an aspect contributing factor of FMS pathophysiology. PMID:30919098
Metabolomics applied to maternal and perinatal health: a review of new frontiers with a translation potential. PMID:30916173
Untargeted Metabolomics Differentiates l-Carnitine Treated Septic Shock 1-Year Survivors and Nonsurvivors. PMID:30895797
Long Noncoding RNA and Protein Interactions: From Experimental Results to Computational Models Based on Network Methods. PMID:30875752
De novo structure determination of 3-((3-aminopropyl)amino)-4-hydroxybenzoic acid, a novel and abundant metabolite in Acinetobacter baylyi ADP1. PMID:30874951
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory. PMID:30862783
A metabolic database for biomedical studies of biopsy specimens by high-resolution magic angle spinning nuclear MR: a qualitative and quantitative tool. PMID:30847981
Metabolomic Insights into Human Arboviral Infections: Dengue, Chikungunya, and Zika Viruses. PMID:30845653
Assessing the Effectiveness of Direct Data Merging Strategy in Long-Term and Large-Scale Pharmacometabonomics. PMID:30842738
Selective galactose culture condition reveals distinct metabolic signatures in pyruvate dehydrogenase and complex I deficient human skin fibroblasts. PMID:30830487
Elevated CO2 and virus infection impacts wheat and aphid metabolism. PMID:30830473
Nitrogen deprivation in Fusarium oxysporum promotes mycotoxin production via intermediates in the Krebs cycle and unreported methylmalonyl-CoA mutase activity. PMID:30830469
RANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies. PMID:30830432
Diagnosis of post-surgical fine-needle aspiration biopsies of thyroid lesions with indeterminate cytology using HRMAS NMR-based metabolomics. PMID:30830426
Juice Index: an integrated Sauvignon blanc grape and wine metabolomics database shows mainly seasonal differences. PMID:30830411
An LC-MS-based lipidomics pre-processing framework underpins rapid hypothesis generation towards CHO systems biotechnology. PMID:30830409
Comparative analysis of creatinine and osmolality as urine normalization strategies in targeted metabolomics for the differential diagnosis of asthma and COPD. PMID:30830407
Identification of a urine metabolite constellation characteristic for kidney allograft rejection. PMID:30830387
Diagnosis of Clostridium difficile infection using an UPLC-MS based metabolomics method. PMID:30830376
Metabolomic characterization of hypertension and dyslipidemia. PMID:30830367
Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement. PMID:30830337
Organic washes of tissue sections for comprehensive analysis of small molecule metabolites by MALDI MS imaging of rat brain following status epilepticus. PMID:30830331
Uncovering the metabolic response of abalone (Haliotis midae) to environmental hypoxia through metabolomics. PMID:30830330
Metabolomic study of the response to cold shock in a strain of Pseudomonas syringae isolated from cloud water. PMID:30830325
Identification of bioactive metabolites using activity metabolomics. PMID:30814649
Function, Detection and Alteration of Acylcarnitine Metabolism in Hepatocellular Carcinoma. PMID:30795537
Quality Control of Therapeutic Peptides by 1H NMR HiFSA Sequencing. PMID:30793905
Multigenerational metabolic profiling in the Michigan PBB registry. PMID:30782538
Transforming presumptive forensic testing: in situ identification and age estimation of human bodily fluids. PMID:30774902
Breast cancer risk in relation to plasma metabolites among Hispanic and African American women. PMID:30771047
Metabolomics Approaches for the Diagnosis and Understanding of Kidney Diseases. PMID:30769897
Sedoheptulose-1,7-bisphospate Accumulation and Metabolic Anomalies in Hepatoma Cells Exposed to Oxidative Stress. PMID:30755786
Data-driven multiple-level analysis of gut-microbiome-immune-joint interactions in rheumatoid arthritis. PMID:30744546
Metabolomic Responses to Manganese Dose in SH-SY5Y Human Neuroblastoma Cells. PMID:30715528
The growing role of precision and personalized medicine for cancer treatment. PMID:30713991
Context-sensitive network analysis identifies food metabolites associated with Alzheimer's disease: an exploratory study. PMID:30704467
NMR Metabolomic Analysis of Skeletal Muscle, Heart, and Liver of Hatchling Loggerhead Sea Turtles (Caretta caretta) Experimentally Exposed to Crude Oil and/or Corexit. PMID:30691098
Biomarkers for Acute Respiratory Distress syndrome and prospects for personalised medicine. PMID:30675131
Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes. PMID:30670556
A Biomphalaria glabrata peptide that stimulates significant behaviour modifications in aquatic free-living Schistosoma mansoni miracidia. PMID:30668561
Dimethyl fumarate treatment induces lipid metabolism alterations that are linked to immunological changes. PMID:30656182
Rapid Cerebral Metabolic Shift during Neonatal Sepsis Is Attenuated by Enteral Colostrum Supplementation in Preterm Pigs. PMID:30641988
Direct Infusion Based Metabolomics Identifies Metabolic Disease in Patients' Dried Blood Spots and Plasma. PMID:30641898
Leveraging Multilayered "Omics" Data for Atopic Dermatitis: A Road Map to Precision Medicine. PMID:30631320
Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. PMID:30619992
NMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort. PMID:30616610
Extending the Scope of 1H NMR Spectroscopy for the Analysis of Cellular Coenzyme A and Acetyl Coenzyme A. PMID:30608643
Vernonia Amygdalina Del. stimulated glucose uptake in brain tissues enhances antioxidative activities; and modulates functional chemistry and dysregulated metabolic pathways. PMID:30607820
Random Forest Analysis of Untargeted Metabolomics Data Suggests Increased Use of Omega Fatty Acid Oxidation Pathway in Drosophila Melanogaster Larvae Fed a Medium Chain Fatty Acid Rich High-Fat Diet. PMID:30602659
Network spectra for drug-target identification in complex diseases: new guns against old foes. PMID:30596144
Plasma mitochondrial DNA and metabolomic alterations in severe critical illness. PMID:30594224
Revealing Different Lung Metastatic Potentials Induced Metabolic Alterations of Hepatocellular Carcinoma Cells via Proton Nuclear Magnetic Resonance Spectroscopy. PMID:30588254
Elucidation of a Human Urine Metabolite as a Seryl-Leucine Glycopeptide and as a Biomarker of Effective Anti-Tuberculosis Therapy. PMID:30585483
Inhibition of early response genes prevents changes in global joint metabolomic profiles in mouse post-traumatic osteoarthritis. PMID:30572121
A robust intracellular metabolite extraction protocol for human neutrophil metabolic profiling. PMID:30571714
Tumor suppressor RARRES1- A novel regulator of fatty acid metabolism in epithelial cells. PMID:30557378
UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways. PMID:30556651
Personalized Medicine and Molecular Interaction Networks in Amyotrophic Lateral Sclerosis (ALS): Current Knowledge. PMID:30551677
Metabolic Signature of Dietary Iron Overload in a Mouse Model. PMID:30544931
Exploratory machine-learned theoretical chemical shifts can closely predict metabolic mixture signals. PMID:30542569
Assessing the potential of sputtered gold nanolayers in mass spectrometry imaging for metabolomics applications. PMID:30540827
Systematic domain-based aggregation of protein structures highlights DNA-, RNA- and other ligand-binding positions. PMID:30535108
Metabolomic Response to Acute Hypoxic Exercise and Recovery in Adult Males. PMID:30534085
Metabolomics for predicting fetal growth restriction: protocol for a systematic review and meta-analysis. PMID:30530473
Metabolome-wide association study of anti-epileptic drug treatment during pregnancy. PMID:30521819
Metabolomic assessment of exposure to near-highway ultrafine particles. PMID:30518795
Serum-based metabolic alterations in patients with papillary thyroid carcinoma unveiled by non-targeted 1H-NMR metabolomics approach. PMID:30483387
A Sensitive and Wide Coverage Ambient Mass Spectrometry Imaging Method for Functional Metabolites Based Molecular Histology. PMID:30479912
Histology-guided high-resolution AP-SMALDI mass spectrometry imaging of wheat-Fusarium graminearum interaction at the root-shoot junction. PMID:30473724
Lung Protection Strategies during Cardiopulmonary Bypass Affect the Composition of Blood Electrolytes and Metabolites-A Randomized Controlled Trial. PMID:30469433
A Simple and Convenient Synthesis of Unlabeled and 13C-Labeled 3-(3-Hydroxyphenyl)-3-Hydroxypropionic Acid and Its Quantification in Human Urine Samples. PMID:30469313
Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity. PMID:30456364
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis. PMID:30449686
Gabapentin Can Suppress Cell Proliferation Independent of the Cytosolic Branched-Chain Amino Acid Transferase 1 (BCAT1). PMID:30427175
Gene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis. PMID:30420728
Biomarker Phenotype for Early Diagnosis and Triage of Sepsis to the Pediatric Intensive Care Unit. PMID:30413795
Imaging Mass Spectrometry Reveals Crosstalk between the Fallopian Tube and the Ovary that Drives Primary Metastasis of Ovarian Cancer. PMID:30410974
The proteomic and metabolomic characterization of exercise-induced sweat for human performance monitoring: A pilot investigation. PMID:30383773
Facilitated Diffusion Mechanisms in DNA Base Excision Repair and Transcriptional Activation. PMID:30379068
Profiling the impact of thermal processing on black raspberry phytochemicals using untargeted metabolomics. PMID:30373008
The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. PMID:30371894
An automated framework for NMR chemical shift calculations of small organic molecules. PMID:30367288
UHPLC-Q-TOF MS-Based Metabolic Analysis for the Therapeutic Efficacy of "Xuebijing Injection" against Sepsis-Induced Acute Lung Injury. PMID:30344613
Alzheimer's Biomarkers From Multiple Modalities Selectively Discriminate Clinical Status: Relative Importance of Salivary Metabolomics Panels, Genetic, Lifestyle, Cognitive, Functional Health and Demographic Risk Markers. PMID:30333744
Oral Administration of Porphyromonas gingivalis Alters the Gut Microbiome and Serum Metabolome. PMID:30333180
Analysis of impact metrics for the Protein Data Bank. PMID:30325351
Screening of candidate substrates and coupling ions of transporters by thermostability shift assays. PMID:30320551
Hydroxyurea Treated β-Thalassemia Children Demonstrate a Shift in Metabolism Towards Healthy Pattern. PMID:30310134
Anti-inflammatory and preventive activity of white mulberry root bark extract in an experimental model of pancreatitis. PMID:30302330
Intracrine Regulation of Estrogen and Other Sex Steroid Levels in Endometrium and Non-gynecological Tissues; Pathology, Physiology, and Drug Discovery. PMID:30283331
A framework for large-scale metabolome drug profiling links coenzyme A metabolism to the toxicity of anti-cancer drug dichloroacetate. PMID:30271981
Profiling the Metabolism of Human Cells by Deep 13C Labeling. PMID:30270114
Lung Protection Strategies during Cardiopulmonary Bypass Affect the Composition of Bronchoalveolar Fluid and Lung Tissue in Cardiac Surgery Patients. PMID:30241409
Salivary metabolite profiling distinguishes patients with oral cavity squamous cell carcinoma from normal controls. PMID:30235319
Particulate metal exposures induce plasma metabolome changes in a commuter panel study. PMID:30231074
Tibetan Medical Formula Shi-Wei-Gan-Ning-Pill Protects Against Carbon Tetrachloride-Induced Liver Fibrosis - An NMR-Based Metabolic Profiling. PMID:30210344
Metabolic profiling and targeted lipidomics reveals a disturbed lipid profile in mothers and fetuses with intrauterine growth restriction. PMID:30206284
Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response. PMID:30193848
900MHz 1H-/13C-NMR analysis of 2-hydroxyglutarate and other brain metabolites in human brain tumor tissue extracts. PMID:30192797
Exploring the potential of NTME/GC-MS, in the establishment of urinary volatomic profiles. Lung cancer patients as case study. PMID:30166567
Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension. PMID:30159317
The Omics Revolution Continues: The Maturation of High-Throughput Biological Data Sources. PMID:30157526
Prenatal Maternal Stress from a Natural Disaster Alters Urinary Metabolomic Profiles in Project Ice Storm Participants. PMID:30154530
Main Human Urinary Metabolites after Genipap (Genipa americana L.) Juice Intake. PMID:30149503
Redox Signaling by Reactive Electrophiles and Oxidants. PMID:30148624
Applications of Parametrized NMR Spin Systems of Small Molecules. PMID:30125102
Online Liquid Chromatography-Sheath-Flow Surface Enhanced Raman Detection of Phosphorylated Carbohydrates. PMID:30119606
T-Probe: An Integrated Microscale Device for Online In Situ Single Cell Analysis and Metabolic Profiling Using Mass Spectrometry. PMID:30119596
Authentic compound-free strategy for simultaneous determination of primary coumarins in Peucedani Radix using offline high performance liquid chromatography-nuclear magnetic resonance spectroscopy-tandem mass spectrometry. PMID:30109188
Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours. PMID:30097636
The Recognition of Unrelated Ligands by Identical Proteins. PMID:30095890
Global metabolomic responses in urine from atm deficient mice in response to LD50/30 gamma irradiation doses. PMID:30095186
Multi-tissue metabolic responses of goldfish (Carassius auratus) exposed to glyphosate-based herbicide. PMID:30090411
New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites. PMID:30090311
Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury. PMID:30069831
A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects. PMID:30048547
Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep. PMID:30046159
DrugMetab: An Integrated Machine Learning and Lexicon Mapping Named Entity Recognition Method for Drug Metabolite. PMID:30033622
Storage conditions modulate the metabolomic profile of a black raspberry nectar with minimal impact on bioactivity. PMID:30022172
Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective. PMID:30020984
NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer. PMID:30016349
Computational Methodologies in the Exploration of Marine Natural Product Leads. PMID:30011882
Metabolic Fingerprinting of Seminal Plasma from Non-obstructive Azoospermia Patients: Positive Versus Negative Sperm Retrieval. PMID:30009145
Metabolic fingerprint of insulin resistance in human polymorphonuclear leucocytes. PMID:30005063
Roux-en-Y gastric bypass surgery alters serum metabolites and fatty acids in patients with morbid obesity. PMID:30003682
The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. PMID:30003207
High-Throughput Metabolomics by 1D NMR. PMID:29999221
Metabolic Profiles of Propofol and Fospropofol: Clinical and Forensic Interpretative Aspects. PMID:29992157
Effect of Tumor Relevant Acidic Environment in the Interaction of a N-hydroxyindole-2-Carboxylic Derivative with the Phospholipid Bilayer. PMID:29987655
Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice. PMID:29982657
MetaboRank: network-based recommendation system to interpret and enrich metabolomics results. PMID:29982278
Higher Concentrations of BCAAs and 3-HIB Are Associated with Insulin Resistance in the Transition from Gestational Diabetes to Type 2 Diabetes. PMID:29967793
SIMPLE: Sparse Interaction Model over Peaks of moLEcules for fast, interpretable metabolite identification from tandem mass spectra. PMID:29950009
Bayesian networks for mass spectrometric metabolite identification via molecular fingerprints. PMID:29949965
Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets. PMID:29946055
Systems-Based Interactome Analysis for Hematopoiesis Effect of Angelicae sinensis Radix: Regulated Network of Cell Proliferation towards Hemopoiesis. PMID:29943236
Karenia brevis allelopathy compromises the lipidome, membrane integrity, and photosynthesis of competitors. PMID:29934632
Metabolomic Profiles for Primary Progressive Multiple Sclerosis Stratification and Disease Course Monitoring. PMID:29915533
Comparative Evaluation of MS-based Metabolomics Software and Its Application to Preclinical Alzheimer's Disease. PMID:29915347
LC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study. PMID:29914076
Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids. PMID:29907951
In silico prediction of potential chemical reactions mediated by human enzymes. PMID:29897324
Increased urinary l-histidine in patients with asthma-COPD overlap: a pilot study. PMID:29892192
Tocotrienol-Rich Fraction of Palm Oil Improves Behavioral Impairments and Regulates Metabolic Pathways in AβPP/PS1 Mice. PMID:29889072
Metabolomics and Ionomics of Potato Tuber Reveals an Influence of Cultivar and Market Class on Human Nutrients and Bioactive Compounds. PMID:29876353
Global untargeted serum metabolomic analyses nominate metabolic pathways responsive to loss of expression of the orphan metallo β-lactamase, MBLAC1. PMID:29868674
A Metabolomics Study of BPTES Altered Metabolism in Human Breast Cancer Cell Lines. PMID:29868609
Combining mechanism-based prediction with patient-based profiling for psoriasis metabolomics biomarker discovery. PMID:29854244
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome. PMID:29851973
Novel Biomarker Candidates for Febrile Neutropenia in Hematological Patients Using Nontargeted Metabolomics. PMID:29849825
In silico design of novel proton-pump inhibitors with reduced adverse effects. PMID:29845582
Burkholderia bacteria use chemotaxis to find social amoeba Dictyostelium discoideum hosts. PMID:29795447
In-Vivo NMR Spectroscopy: A Powerful and Complimentary Tool for Understanding Environmental Toxicity. PMID:29795000
Target-Decoy-Based False Discovery Rate Estimation for Large-Scale Metabolite Identification. PMID:29790753
Association of Plasma Lipids and Polar Metabolites with Low Bone Mineral Density in Singaporean-Chinese Menopausal Women: A Pilot Study. PMID:29789485
Lipid metabolism reprogramming and its potential targets in cancer. PMID:29784041
Oral ibuprofen differentially affects plasma and sweat lipid mediator profiles in healthy adult males. PMID:29778785
Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses. PMID:29775592
The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation. PMID:29749372
Androgen Receptor Signaling in Castration-Resistant Prostate Cancer Alters Hyperpolarized Pyruvate to Lactate Conversion and Lactate Levels In Vivo. PMID:29748904
Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics. PMID:29748461
Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. PMID:29742587
1H-NMR metabolomic profiling reveals a distinct metabolic recovery response in shoots and roots of temporarily drought-stressed sugar beets. PMID:29738573
Comparative metabolomics of aging in a long-lived bat: Insights into the physiology of extreme longevity. PMID:29715267
Metabolite profiling for biomarkers in Schistosoma haematobium infection and associated bladder pathologies. PMID:29708967
Serum metabolomics using ultra performance liquid chromatography coupled to mass spectrometry in lactating dairy cows following a single dose of sporidesmin. PMID:29706850
An untargeted metabolomics method for archived newborn dried blood spots in epidemiologic studies. PMID:29706849
Cardiovascular Metabolomics. PMID:29700070
A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. PMID:29695840
Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice. PMID:29686991
Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells. PMID:29684492
A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence. PMID:29679203
Identifying diseases-related metabolites using random walk. PMID:29671398
Discovery of Lipidome Alterations Following Traumatic Brain Injury via High-Resolution Metabolomics. PMID:29671324
A systems biology approach to predict and characterize human gut microbial metabolites in colorectal cancer. PMID:29670137
Propagating annotations of molecular networks using in silico fragmentation. PMID:29668671
A prototypic small molecule database for bronchoalveolar lavage-based metabolomics. PMID:29664467
Substrate Specificities and Efflux Efficiencies of RND Efflux Pumps of Acinetobacter baumannii. PMID:29661860
Metabolomic study of human tissue and urine in clear cell renal carcinoma by LC-HRMS and PLS-DA. PMID:29658093
Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung. PMID:29656123
Novel Indole-fused benzo-oxazepines (IFBOs) inhibit invasion of hepatocellular carcinoma by targeting IL-6 mediated JAK2/STAT3 oncogenic signals. PMID:29651140
Extraction and Analysis of Pan-metabolome Polar Metabolites by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS). PMID:29623284
Discrimination between the human prostate normal and cancer cell exometabolome by GC-MS. PMID:29615722
High Glucose-Induced Cardiomyocyte Death May Be Linked to Unbalanced Branched-Chain Amino Acids and Energy Metabolism. PMID:29614759
Bayesian estimation of the number of protonation sites for urinary metabolites from NMR spectroscopic data. PMID:29606928
Route of Glucose Uptake in the Group a Streptococcus Impacts SLS-Mediated Hemolysis and Survival in Human Blood. PMID:29594067
Intestinal Metagenomes and Metabolomes in Healthy Young Males: Inactivity and Hypoxia Generated Negative Physiological Symptoms Precede Microbial Dysbiosis. PMID:29593560
Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer. PMID:29582397
The Transcriptional Regulator BpsR Controls the Growth of Bordetella bronchiseptica by Repressing Genes Involved in Nicotinic Acid Degradation. PMID:29581411
Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier. PMID:29562936
Placenta-Derived Cells for Acute Brain Injury. PMID:29562781
GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells. PMID:29562689
Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques. PMID:29562241
Unraveling the unknown areas of the human metabolome: the role of infrared ion spectroscopy. PMID:29556837
Tulobuterol patch alleviates allergic asthmic inflammation by blockade of Syk and NF-κB activation in mice. PMID:29552299
Metabolic profiling of the three neural derived embryonal pediatric tumors retinoblastoma, neuroblastoma and medulloblastoma, identifies distinct metabolic profiles. PMID:29541417
Multiomics tools for the diagnosis and treatment of rare neurological disease. PMID:29536202
Probing the application range and selectivity of a differential mobility spectrometry-mass spectrometry platform for metabolomics. PMID:29532192
IMPPAT: A curated database of Indian Medicinal Plants, Phytochemistry And Therapeutics. PMID:29531263
Untargeted metabolomics reveals multiple metabolites influencing smoking-related DNA methylation. PMID:29528243
IntLIM: integration using linear models of metabolomics and gene expression data. PMID:29506475
Expanding the Coverage of the Metabolome with Nitrogen-Based NMR. PMID:29505241
From correlation to causation: analysis of metabolomics data using systems biology approaches. PMID:29503602
Study of the Serum Metabolomic Profile in Nonalcoholic Fatty Liver Disease: Research and Clinical Perspectives. PMID:29495258
speaq 2.0: A complete workflow for high-throughput 1D NMR spectra processing and quantification. PMID:29494588
Susceptibility and tolerance of rice crop to salt threat: Physiological and metabolic inspections. PMID:29489838
Elastic net regularized regression for time-series analysis of plasma metabolome stability under sub-optimal freezing condition. PMID:29483546
Diastolic Dysfunction in Individuals With Human Immunodeficiency Virus Infection: Literature Review, Rationale and Design of the Characterizing Heart Function on Antiretroviral Therapy (CHART) Study. PMID:29482027
Recommended strategies for spectral processing and post-processing of 1D 1H-NMR data of biofluids with a particular focus on urine. PMID:29479299
Borrelia burgdorferi genes, bb0639-0642, encode a putative putrescine/spermidine transport system, PotABCD, that is spermidine specific and essential for cell survival. PMID:29476656
Differences in Urinary Amino Acid Patterns in Individuals with Different Types of Urological Tumor Urinary Amino Acid Patterns as Markers of Urological Tumors. PMID:29475932
1H NMR-Based Identification of Intestinally Absorbed Metabolites by Ussing Chamber Analysis of the Rat Cecum. PMID:29474787
RaMP: A Comprehensive Relational Database of Metabolomics Pathways for Pathway Enrichment Analysis of Genes and Metabolites. PMID:29470400
Application of kernel principal component analysis and computational machine learning to exploration of metabolites strongly associated with diet. PMID:29467421
Serum Metabolomics of Activity Energy Expenditure and its Relation to Metabolic Syndrome and Obesity. PMID:29459697
Metabolic Profile of Oral Squamous Carcinoma Cell Lines Relies on a Higher Demand of Lipid Metabolism in Metastatic Cells. PMID:29456966
Characterization of a novel miniaturized burst-mode infrared laser system for IR-MALDESI mass spectrometry imaging. PMID:29455285
Monitoring of erlotinib in pancreatic cancer patients during long-time administration and comparison to a physiologically based pharmacokinetic model. PMID:29453635
Plasma and urinary metabolomic profiles of Down syndrome correlate with alteration of mitochondrial metabolism. PMID:29445163
Ion-neutral Clustering of Bile Acids in Electrospray Ionization Across UPLC Flow Regimes. PMID:29427066
Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics. PMID:29425024
Metabolomic alterations in invasive ductal carcinoma of breast: A comprehensive metabolomic study using tissue and serum samples. PMID:29416801
Application of Metabolomics in Alzheimer's Disease. PMID:29375465
Targeted and Untargeted Metabolic Profiling of Wild Grassland Plants identifies Antibiotic and Anthelmintic Compounds Targeting Pathogen Physiology, Metabolism and Reproduction. PMID:29374230
Metabolite Profiling of 14 Wuyi Rock Tea Cultivars Using UPLC-QTOF MS and UPLC-QqQ MS Combined with Chemometrics. PMID:29364152
The role of the clinician in the multi-omics era: are you ready? PMID:29362952
From Genomics to Omics Landscapes of Parkinson's Disease: Revealing the Molecular Mechanisms. PMID:29356624
Serum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry. PMID:29354104
Discovering Altered Regulation and Signaling Through Network-based Integration of Transcriptomic, Epigenomic, and Proteomic Tumor Data. PMID:29344883
Structure Elucidation of Unknown Metabolites in Metabolomics by Combined NMR and MS/MS Prediction. PMID:29342073
Untargeted Metabolomics Approach in Halophiles: Understanding the Biodeterioration Process of Building Materials. PMID:29321766
Combined Metabolomic Analysis of Plasma and Urine Reveals AHBA, Tryptophan and Serotonin Metabolism as Potential Risk Factors in Gestational Diabetes Mellitus (GDM). PMID:29312952
Construction of Viable Soil Defined Media Using Quantitative Metabolomics Analysis of Soil Metabolites. PMID:29312276
Chemical encoding of risk perception and predator detection among estuarine invertebrates. PMID:29311305
Metabolomics technology and bioinformatics for precision medicine. PMID:29304189
Network-Based Differential Analysis to Identify Molecular Features of Tumorigenesis for Esophageal Squamous Carcinoma. PMID:29301256
Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data. PMID:29291722
Unique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis. PMID:29291380
1H-NMR metabolomic study of whole blood from hatchling loggerhead sea turtles (Caretta caretta) exposed to crude oil and/or Corexit. PMID:29291126
Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA. PMID:29288256
Microprobe Capillary Electrophoresis Mass Spectrometry for Single-cell Metabolomics in Live Frog (Xenopus laevis) Embryos. PMID:29286491
Synthesis of [15 N]-cholamine bromide hydrobromide. PMID:29278650
The Major Chromophore Arising from Glucose Degradation and Oxidative Stress Occurrence during Lens Proteins Glycation Induced by Glucose. PMID:29271874
Identification of SPOP related metabolic pathways in prostate cancer. PMID:29262542
Molecular structures enumeration and virtual screening in the chemical space with RetroPath2.0. PMID:29260340
Nutritional metabolomics in critical illness. PMID:29251691
Linking physiologically-based pharmacokinetic and genome-scale metabolic networks to understand estradiol biology. PMID:29246152
Hepatic Dysfunction Caused by Consumption of a High-Fat Diet. PMID:29241556
A Chemometrics Approach for Nuclear Magnetic Resonance Data to Characterize the Partial Metabolome Banana Peels from Southern Brazil. PMID:29236677
EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer. PMID:29228577
Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines. PMID:29226804
Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections. PMID:29221465
Untargeted serum metabonomics study of psoriasis vulgaris based on ultra-performance liquid chromatography coupled to mass spectrometry. PMID:29221177
Database of resistance related metabolites in Wheat Fusarium head blight Disease (MWFD). PMID:29220474
Null diffusion-based enrichment for metabolomics data. PMID:29211807
Urinary metabolomic analysis to identify preterm neonates exposed to histological chorioamnionitis: A pilot study. PMID:29211784
Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease. PMID:29208041
Rhizobium Impacts on Seed Productivity, Quality, and Protection of Pisum sativum upon Disease Stress Caused by Didymella pinodes: Phenotypic, Proteomic, and Metabolomic Traits. PMID:29204150
Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy. PMID:29194434
Exploring the Impact of Food on the Gut Ecosystem Based on the Combination of Machine Learning and Network Visualization. PMID:29194366
New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report. PMID:29192815
Annotation of Peptide Structures Using SMILES and Other Chemical Codes-Practical Solutions. PMID:29186902
Metabolic Perturbations in a Bacillus subtilis clpP Mutant during Glucose Starvation. PMID:29186773
Metabolites Associated With Risk of Developing Mobility Disability in the Health, Aging and Body Composition Study. PMID:29186400
Chemometric and high-resolution mass spectrometry tools for the characterization and comparison of raw and treated wastewater samples of a pilot plant on the SIPIBEL site. PMID:29170926
Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer. PMID:29170516
Deconvoluting interrelationships between concentrations and chemical shifts in urine provides a powerful analysis tool. PMID:29162796
Improving Metabolic Health Through Precision Dietetics in Mice. PMID:29158425
Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91. PMID:29157600
Evaluation of sample extracting methods of FCSM by Lactobacillus acidophilus based on a UPLC-Q-TOF-MS global metabolomics analysis. PMID:29154014
Metabolic Biomarkers in Heart Failure. PMID:29153196
Genomic, Transcriptomic, and Phenotypic Analyses of Neisseria meningitidis Isolates from Disease Patients and Their Household Contacts. PMID:29152586
Untargeted mass spectrometry discloses plasma solute levels poorly controlled by hemodialysis. PMID:29145509
A role for bacterial urease in gut dysbiosis and Crohn's disease. PMID:29141885
HMDB 4.0: the human metabolome database for 2018. PMID:29140435
Structural elucidation of novel biomarkers of known metabolic disorders based on multistage fragmentation mass spectra. PMID:29139026
Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells. PMID:29137304
WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research. PMID:29136241
Metabolomics identifies metabolite biomarkers associated with acute rejection after heart transplantation in rats. PMID:29133921
Metabolic profiles of adipose-derived and bone marrow-derived stromal cells from elderly coronary heart disease patients by capillary liquid chromatography quadrupole time-of-flight mass spectrometry. PMID:29115374
PAMDB: a comprehensive Pseudomonas aeruginosa metabolome database. PMID:29106626
mVOC 2.0: a database of microbial volatiles. PMID:29106611
Effects of targeting SLC1A5 on inhibiting gastric cancer growth and tumor development in vitro and in vivo. PMID:29100325
Critical Assessment of Small Molecule Identification 2016: automated methods. PMID:29086042
Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes. PMID:29083323
5H-benzo[h]thiazolo[2,3-b]quinazolines ameliorate NDEA-induced hepatocellular carcinogenesis in rats through IL-6 downregulation along with oxidative and metabolic stress reduction. PMID:29075102
jMorp: Japanese Multi Omics Reference Panel. PMID:29069501
Metabolic Comparison of Dorsal versus Ventral Cells Directly in the Live 8-cell Frog Embryo by Microprobe Single-cell CE-ESI-MS. PMID:29062391
Spin System Modeling of Nuclear Magnetic Resonance Spectra for Applications in Metabolomics and Small Molecule Screening. PMID:29058410
Bacterial Substrate Transformation Tracked by Stable-Isotope-Guided NMR Metabolomics: Application in a Natural Aquatic Microbial Community. PMID:29048351
The dental calculus metabolome in modern and historic samples. PMID:29046620
UC2 search: using unique connectivity of uncharged compounds for metabolite annotation by database searching in mass spectrometry-based metabolomics. PMID:29040459
Annotation: A Computational Solution for Streamlining Metabolomics Analysis. PMID:29039932
Elevated pentose phosphate pathway is involved in the recovery of hypoxia‑induced erythrocytosis. PMID:29039604
Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells. PMID:29036472
A Systematic Review of Techniques and Sources of Big Data in the Healthcare Sector. PMID:29032458
Quantitative time-course metabolomics in human red blood cells reveal the temperature dependence of human metabolic networks. PMID:29030425
NMR spectroscopy and electron microscopy identification of metabolic and ultrastructural changes to the kidney following ischemia-reperfusion injury. PMID:28978534
Dietary and health biomarkers-time for an update. PMID:28974991
MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux. PMID:28965765
Ion Mobility Spectrometry-Mass Spectrometry Coupled with Gas-Phase Hydrogen/Deuterium Exchange for Metabolomics Analyses. PMID:28956290
Direct detection of surface localized specialized metabolites from Glycyrrhiza lepidota (American licorice) by leaf spray mass spectrometry. PMID:28956161
Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications. PMID:28955291
Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig. PMID:28955207
Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity. PMID:28947825
Metabolomic Approaches in Cancer Epidemiology. PMID:28943618
Metabolic assessment of a migraine model using relaxation-enhanced 1 H spectroscopy at ultrahigh field. PMID:28921630
Recent urbanization in China is correlated with a Westernized microbiome encoding increased virulence and antibiotic resistance genes. PMID:28915922
Navigating freely-available software tools for metabolomics analysis. PMID:28890673
6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid attenuates heptatocellular carcinoma in rats with NMR-based metabolic perturbations. PMID:28884001
Emerging Omics Approaches in Aging Research. PMID:28874057
Chronic obstructive pulmonary disease candidate gene prioritization based on metabolic networks and functional information. PMID:28873096
Nanoformulated copper/zinc superoxide dismutase exerts differential effects on glucose vs lipid homeostasis depending on the diet composition possibly via altered AMPK signaling. PMID:28867395
Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of Mycobacterium tuberculosis during Early Macrophage Infection. PMID:28845460
Integrative metabolomics as emerging tool to study autophagy regulation. PMID:28845422
Advances in metabolome information retrieval: turning chemistry into biology. Part II: biological information recovery. PMID:28842777
Probing the Genome-Scale Metabolic Landscape of Bordetella pertussis, the Causative Agent of Whooping Cough. PMID:28842544
Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma. PMID:28841195
Trans-omics approaches used to characterise fish nutritional biorhythms in leopard coral grouper (Plectropomus leopardus). PMID:28839183
Metabolomics reveals distinct neurochemical profiles associated with stress resilience. PMID:28828396
A Serum Small Molecule Biosignature of Radiation Exposure from Total Body Irradiated Patients. PMID:28825479
Impact of novel palmitoylated prolactin-releasing peptide analogs on metabolic changes in mice with diet-induced obesity. PMID:28820912
A metabolomics guided exploration of marine natural product chemical space. PMID:28819353
Metabolomics of biomarker discovery in ovarian cancer: a systematic review of the current literature. PMID:28819352
Combined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems. PMID:28819133
Pre-analytic evaluation of volumetric absorptive microsampling and integration in a mass spectrometry-based metabolomics workflow. PMID:28815270
Leveraging network analytics to infer patient syndrome and identify causal genes in rare disease cases. PMID:28812537
Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells. PMID:28809118
Metabolomic profiles of plasma, exhaled breath condensate, and saliva are correlated with potential for air toxics detection. PMID:28808178
Assessment of gold nanoparticles on human peripheral blood cells by metabolic profiling with 1H-NMR spectroscopy, a novel translational approach on a patient-specific basis. PMID:28793337
Elucidating the Structure of N1-Acetylisoputreanine: A Novel Polyamine Catabolite in Human Urine. PMID:28782053
New frontiers in metabolomics: from measurement to insight. PMID:28781759
Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus. PMID:28779078
NuBBEDB: an updated database to uncover chemical and biological information from Brazilian biodiversity. PMID:28775335
Using omics approaches to understand pulmonary diseases. PMID:28774304
Nitrite Derived from Endogenous Bacterial Nitric Oxide Synthase Activity Promotes Aerobic Respiration. PMID:28765220
Diagnosis of coinfection by schistosomiasis and viral hepatitis B or C using 1H NMR-based metabonomics. PMID:28763497
Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness. PMID:28754919
Repression of Salmonella Host Cell Invasion by Aromatic Small Molecules from the Human Fecal Metabolome. PMID:28754707
Microscale Mass Spectrometry Analysis of Extracellular Metabolites in Live Multicellular Tumor Spheroids. PMID:28753268
1H NMR Metabolic Profiling of Earthworm (Eisenia fetida) Coelomic Fluid, Coelomocytes, and Tissue: Identification of a New Metabolite-Malylglutamate. PMID:28753027
Metabolome alterations in severe critical illness and vitamin D status. PMID:28750641
The Saliva Exposome for Monitoring of Individuals' Health Trajectories. PMID:28743678
NMR analysis reveals significant differences in the plasma metabolic profiles of Niemann Pick C1 patients, heterozygous carriers, and healthy controls. PMID:28740230
The whole-genome landscape of medulloblastoma subtypes. PMID:28726821
MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer. PMID:28697344
Use of fecal volatile organic compound analysis to discriminate between non-vaccinated and BCG-Vaccinated cattle prior to and after Mycobacterium bovis challenge. PMID:28686691
NMR Profiling of Metabolites in Larval and Juvenile Blue Mussels (Mytilus edulis) under Ambient and Low Salinity Conditions. PMID:28684716
Metabolomic Studies in Drosophila. PMID:28684601
Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei. PMID:28679527
Enriching plausible new hypothesis generation in PubMed. PMID:28678852
Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes. PMID:28656061
Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. PMID:28654323
Causal Genetic Variation Underlying Metabolome Differences. PMID:28652377
Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach. PMID:28649439
Environmental influences in the etiology of colorectal cancer: the premise of metabolomics. PMID:28642837
Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin-lysoPA axis in COPD. PMID:28642310
Development and Validation of a High-Throughput Mass Spectrometry Based Urine Metabolomic Test for the Detection of Colonic Adenomatous Polyps. PMID:28640228
Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention. PMID:28628112
Molecular Biomarkers of Colorectal Cancer and Cancer Disparities: Current Status and Perspective. PMID:28626361
Unsupervised Discovery and Comparison of Structural Families Across Multiple Samples in Untargeted Metabolomics. PMID:28621528
Drug repositioning for enzyme modulator based on human metabolite-likeness. PMID:28617219
Metabolomics Analysis of Effects of Commercial Soy-based Protein Products in Red Drum (Sciaenops ocellatus). PMID:28613908
Does the 1H-NMR plasma metabolome reflect the host-tumor interactions in human breast cancer? PMID:28611296
Tryptophan status in autism spectrum disorder and the influence of supplementation on its level. PMID:28608247
BioM2MetDisease: a manually curated database for associations between microRNAs, metabolites, small molecules and metabolic diseases. PMID:28605773
MetabolitePredict: A de novo human metabolomics prediction system and its applications in rheumatoid arthritis. PMID:28600026
A methodology for elucidating regulatory mechanisms leading to changes in lipid profiles. PMID:28596719
Diagnostic Applications of Nuclear Magnetic Resonance-Based Urinary Metabolomics. PMID:28579794
Maximal clique method for the automated analysis of NMR TOCSY spectra of complex mixtures. PMID:28573376
On the effects of alternative optima in context-specific metabolic model predictions. PMID:28557990
"Gestaltomics": Systems Biology Schemes for the Study of Neuropsychiatric Diseases. PMID:28536537
Unique identifiers for small molecules enable rigorous labeling of their atoms. PMID:28534867
Livestock metabolomics and the livestock metabolome: A systematic review. PMID:28531195
From chromatogram to analyte to metabolite. How to pick horses for courses from the massive web resources for mass spectral plant metabolomics. PMID:28520864
Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. PMID:28492366
Changes in human hepatic metabolism in steatosis and cirrhosis. PMID:28487605
Metabolic Dysregulation after Neutron Exposures Expected from an Improvised Nuclear Device. PMID:28475424
In Situ Microprobe Single-Cell Capillary Electrophoresis Mass Spectrometry: Metabolic Reorganization in Single Differentiating Cells in the Live Vertebrate (Xenopus laevis) Embryo. PMID:28434226
Low-molecular-weight components of the metabolome control the proliferative activity in cellular and bacterial cultures. PMID:28429257
Cytoskeletal stability and metabolic alterations in primary human macrophages in long-term microgravity. PMID:28419128
Time resolved and label free monitoring of extracellular metabolites by surface enhanced Raman spectroscopy. PMID:28419111
Metabolite marker discovery for the detection of bladder cancer by comparative metabolomics. PMID:28415579
Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics. PMID:28413374
LipidFinder: A computational workflow for discovery of lipids identifies eicosanoid-phosphoinositides in platelets. PMID:28405621
Plasma metabolomics in adults with cystic fibrosis during a pulmonary exacerbation: A pilot randomized study of high-dose vitamin D3 administration. PMID:28403943
Determining the presence of asthma-related molecules and salivary contamination in exhaled breath condensate. PMID:28403875
Brain metabolomic profiling of eastern honey bee (Apis cerana) infested with the mite Varroa destructor. PMID:28403242
Visceral adipose tissue but not subcutaneous adipose tissue is associated with urine and serum metabolites. PMID:28403191
Microbial metabolites in health and disease: Navigating the unknown in search of function. PMID:28389566
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase. PMID:28388410
Improved Quantum Chemical NMR Chemical Shift Prediction of Metabolites in Aqueous Solution toward the Validation of Unknowns. PMID:28388058
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion. PMID:28380376
Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity. PMID:28373578
Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics. PMID:28364225
Comprehensive Optimization of LC-MS Metabolomics Methods Using Design of Experiments (COLMeD). PMID:28348510
metaX: a flexible and comprehensive software for processing metabolomics data. PMID:28327092
Whole Blood Metabolomics by 1H NMR Spectroscopy Provides a New Opportunity To Evaluate Coenzymes and Antioxidants. PMID:28318242
Metabolomics approaches in pancreatic adenocarcinoma: tumor metabolism profiling predicts clinical outcome of patients. PMID:28298227
Virtual screening applications in short-chain dehydrogenase/reductase research. PMID:28286207
DAPNe with micro-capillary separatory chemistry-coupled to MALDI-MS for the analysis of polar and non-polar lipid metabolism in one cell. PMID:28251574
Early Effect of Amyloid β-Peptide on Hippocampal and Serum Metabolism in Rats Studied by an Integrated Method of NMR-Based Metabolomics and ANOVA-Simultaneous Component Analysis. PMID:28243597
Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network. PMID:28243200
The Importance of Endophenotypes to Evaluate the Relationship between Genotype and External Phenotype. PMID:28241430
The human brain produces fructose from glucose. PMID:28239653
Positional Enrichment by Proton Analysis (PEPA): A One-Dimensional 1 H-NMR Approach for 13 C Stable Isotope Tracer Studies in Metabolomics. PMID:28220994
IMPACT OF TIGECYCLINE VERSUS OTHER ANTIBIOTICS ON THE FECAL METABOLOME AND ON COLONIZATION RESISTANCE TO CLOSTRIDIUM DIFFICILE IN MICE. PMID:28217763
1H NMR-based serum metabolomics reveals erythromycin-induced liver toxicity in albino Wistar rats. PMID:28216958
Epimetabolites: discovering metabolism beyond building and burning. PMID:28213207
Evidence of a DHA Signature in the Lipidome and Metabolome of Human Hepatocytes. PMID:28208746
An integrative metabolomics and transcriptomics study to identify metabolic alterations in aged skin of humans in vivo. PMID:28201987
β-Thalassemia Patients Revealed a Significant Change of Untargeted Metabolites in Comparison to Healthy Individuals. PMID:28198811
NMR metabolic fingerprints of murine melanocyte and melanoma cell lines: application to biomarker discovery. PMID:28198377
Metabolomic and Metagenomic Analysis of Two Crude Oil Production Pipelines Experiencing Differential Rates of Corrosion. PMID:28197141
Metabolomics: A Primer. PMID:28196646
Untargeted metabolomics of colonic digests reveals kynurenine pathway metabolites, dityrosine and 3-dehydroxycarnitine as red versus white meat discriminating metabolites. PMID:28195169
Comprehensive Metabolite Identification Strategy Using Multiple Two-Dimensional NMR Spectra of a Complex Mixture Implemented in the COLMARm Web Server. PMID:28193069
Cuprizone Intoxication Induces Cell Intrinsic Alterations in Oligodendrocyte Metabolism Independent of Copper Chelation. PMID:28186720
β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling. PMID:28161796
Changes in Lipidome Composition during Brain Development in Humans, Chimpanzees, and Macaque Monkeys. PMID:28158622
Mixing omics: combining genetics and metabolomics to study rheumatic diseases. PMID:28148918
Serum Metabolomics of Burkitt Lymphoma Mouse Models. PMID:28129369
Parenteral and enteral nutrition in surgical critical care: Plasma metabolomics demonstrates divergent effects on nitrogen, fatty-acid, ribonucleotide, and oxidative metabolism. PMID:28129265
Assessment of Metabolic Changes in Mycobacterium smegmatis Wild-Type and alr Mutant Strains: Evidence of a New Pathway of d-Alanine Biosynthesis. PMID:28121156
Proposed Confidence Scale and ID Score in the Identification of Known-Unknown Compounds Using High Resolution MS Data. PMID:28116700
Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. PMID:28112165
Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole‑time‑of‑flight mass spectrometry. PMID:28098892
New-generation mass spectrometry expands the toolbox of cell and developmental biology. PMID:28095647
Metabolomics and Metabolic Diseases: Where Do We Stand? PMID:28094011
Serum Metabolomic Profiles Identify ER-Positive Early Breast Cancer Patients at Increased Risk of Disease Recurrence in a Multicenter Population. PMID:28082280
Metabolomic profiles as reliable biomarkers of dietary composition. PMID:28077380
Predicting the Metabolic Sites by Flavin-Containing Monooxygenase on Drug Molecules Using SVM Classification on Computed Quantum Mechanics and Circular Fingerprints Molecular Descriptors. PMID:28072829
Identification of altered brain metabolites associated with TNAP activity in a mouse model of hypophosphatasia using untargeted NMR-based metabolomics analysis. PMID:28072448
NMR-based metabolomics reveals brain region-specific metabolic alterations in streptozotocin-induced diabetic rats with cognitive dysfunction. PMID:28070703
The 24th annual Nucleic Acids Research database issue: a look back and upcoming changes. PMID:28053160
Metabolites Associated With Lean Mass and Adiposity in Older Black Men. PMID:28052980
Arginine and Lysine Transporters Are Essential for Trypanosoma brucei. PMID:28045943
Uremic Solutes in Chronic Kidney Disease and Their Role in Progression. PMID:28033375
Identifying biomarkers of dietary patterns by using metabolomics. PMID:28031192
Considerations when choosing a genetic model organism for metabolomics studies. PMID:28025166
Host-Microbiome Interaction and Cancer: Potential Application in Precision Medicine. PMID:28018236
Metabolomics with Nuclear Magnetic Resonance Spectroscopy in a Drosophila melanogaster Model of Surviving Sepsis. PMID:28009836
Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS. PMID:28000704
Current and Future Perspectives on the Structural Identification of Small Molecules in Biological Systems. PMID:27983674
The BioGRID interaction database: 2017 update. PMID:27980099
xMSannotator: An R Package for Network-Based Annotation of High-Resolution Metabolomics Data. PMID:27977166
Epithelial ovarian carcinoma diagnosis by desorption electrospray ionization mass spectrometry imaging. PMID:27976698
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit. PMID:27955696
Fluid-Based Biomarkers for Amyotrophic Lateral Sclerosis. PMID:27933485
Internet Databases of the Properties, Enzymatic Reactions, and Metabolism of Small Molecules-Search Options and Applications in Food Science. PMID:27929431
Metabolic pathway reconstruction strategies for central metabolism and natural product biosynthesis. PMID:27924274
Early Diagnosis of Brain Metastases Using a Biofluids-Metabolomics Approach in Mice. PMID:27924154
Exposome-Explorer: a manually-curated database on biomarkers of exposure to dietary and environmental factors. PMID:27924041
Integrating ion mobility spectrometry into mass spectrometry-based exposome measurements: what can it add and how far can it go? PMID:27921453
YMDB 2.0: a significantly expanded version of the yeast metabolome database. PMID:27899612
Metabolic Signatures of Lung Cancer in Sputum and Exhaled Breath Condensate Detected by 1H Magnetic Resonance Spectroscopy: A Feasibility Study. PMID:27891048
Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease. PMID:27889911
Electrospray deposition device used to precisely control the matrix crystal to improve the performance of MALDI MSI. PMID:27885266
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. PMID:27883890
Mass spectrometry imaging: a novel technology in rheumatology. PMID:27881864
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences. PMID:27881428
Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells. PMID:27878243
Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. PMID:27874830
ClassyFire: automated chemical classification with a comprehensive, computable taxonomy. PMID:27867422
Rule-Mining for the Early Prediction of Chronic Kidney Disease Based on Metabolomics and Multi-Source Data. PMID:27861591
Nuclear Magnetic Resonance metabolomics reveals an excretory metabolic signature of renal cell carcinoma. PMID:27857216
Topic modeling for untargeted substructure exploration in metabolomics. PMID:27856765
A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX. PMID:27852928
Serum metabolomics analysis of patients with chikungunya and dengue mono/co-infections reveals distinct metabolite signatures in the three disease conditions. PMID:27845374
FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry. PMID:27842059
SPLASH, a hashed identifier for mass spectra. PMID:27824832
A Comparative Metabolomics Approach Reveals Early Biomarkers for Metabolic Response to Acute Myocardial Infarction. PMID:27821850
Concurrent profiling of polar metabolites and lipids in human plasma using HILIC-FTMS. PMID:27819279
The Poly (ADP-Ribose) Polymerase Inhibitor Veliparib and Radiation Cause Significant Cell Line Dependent Metabolic Changes in Breast Cancer Cells. PMID:27811964
Loss-of-function screens of druggable targetome against cancer stem-like cells. PMID:27811063
Metabolic effects of basic fibroblast growth factor in streptozotocin-induced diabetic rats: A 1H NMR-based metabolomics investigation. PMID:27808173
Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. PMID:27789671
Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models. PMID:27784287
Effects of 14-day oral low dose selenium nanoparticles and selenite in rat-as determined by metabolite pattern determination. PMID:27781177
Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function. PMID:27780848
Sheathless Capillary Electrophoresis-Mass Spectrometry for Metabolic Profiling of Biological Samples. PMID:27768073
Validation of highly sensitive simultaneous targeted and untargeted analysis of keto-steroids by Girard P derivatization and stable isotope dilution-liquid chromatography-high resolution mass spectrometry. PMID:27743906
NMR based serum metabolomics reveals a distinctive signature in patients with Lupus Nephritis. PMID:27739464
Lysozyme and bilirubin bind to ACE and regulate its conformation and shedding. PMID:27734897
Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats. PMID:27732780
Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome. PMID:27729833
Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli. PMID:27713404
The metabolome 18 years on: a concept comes of age. PMID:27695392
A capillary electrophoresis coupled to mass spectrometry pipeline for long term comparable assessment of the urinary metabolome. PMID:27694997
An overview of renal metabolomics. PMID:27692817
Metabolic Profiling of Intact Arabidopsis thaliana Leaves during Circadian Cycle Using 1H High Resolution Magic Angle Spinning NMR. PMID:27662620
Cyanidin-3-O-glucoside: Physical-Chemistry, Foodomics and Health Effects. PMID:27657039
Multivariate data validation for investigating primary HCMV infection in pregnancy. PMID:27656676
Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors. PMID:27651895
XMetDB: an open access database for xenobiotic metabolism. PMID:27651835
Quantitative metabolomics of photoreceptor degeneration and the effects of stem cell-derived retinal pigment epithelium transplantation. PMID:27644974
Increasing rigor in NMR-based metabolomics through validated and open source tools. PMID:27643760
Theoretical investigation of loratadine reactivity in order to understand its degradation properties: DFT and MD study. PMID:27640160
[Metabolome analysis of solid tumors]. PMID:27638539
Computational Metabolomics: A Framework for the Million Metabolome. PMID:27629808
Systems Medicine as an Emerging Tool for Cardiovascular Genetics. PMID:27626034
Untargeted Metabolomics Strategies-Challenges and Emerging Directions. PMID:27624161
Techniques and Approaches to Genetic Analyses in Nephrological Disorders. PMID:27617137
Urine metabolome profiling of immune-mediated inflammatory diseases. PMID:27609333
Metabolomic profiling of brain from infants who died from Sudden Infant Death Syndrome reveals novel predictive biomarkers. PMID:27608295
Perturbational Profiling of Metabolites in Patient Fibroblasts Implicates α-Aminoadipate as a Potential Biomarker for Bipolar Disorder. PMID:27606323
Juvenile Male Rats Exposed to a Low-Dose Mixture of Twenty-Seven Environmental Chemicals Display Adverse Health Effects. PMID:27598887
A rapid method for quantifying free and bound acetate based on alkylation and GC-MS analysis. PMID:27594997
Arginine: New Insights into Growth Performance and Urinary Metabolomic Profiles of Rats. PMID:27589702
Towards understanding brain-gut-microbiome connections in Alzheimer's disease. PMID:27585440
An Untargeted Metabolomics Approach to Characterize Short-Term and Long-Term Metabolic Changes after Bariatric Surgery. PMID:27584017
Metabolite Analysis and Histology on the Exact Same Tissue: Comprehensive Metabolomic Profiling and Metabolic Classification of Prostate Cancer. PMID:27578275
Phospholipid Species in Newborn and 4 Month Old Infants after Consumption of Different Formulas or Breast Milk. PMID:27571269
Plasma Biomarkers for Monitoring Brain Pathophysiology in FMR1 Premutation Carriers. PMID:27570505
Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut. PMID:27562254
Plasma metabolic profile delineates roles for neurodegeneration, pro-inflammatory damage and mitochondrial dysfunction in the FMR1 premutation. PMID:27555610
Knowns and unknowns in metabolomics identified by multidimensional NMR and hybrid MS/NMR methods. PMID:27552705
MetaboTools: A Comprehensive Toolbox for Analysis of Genome-Scale Metabolic Models. PMID:27536246
Urinary Metabolomic Approach Provides New Insights into Distinct Metabolic Profiles of Glutamine and N-Carbamylglutamate Supplementation in Rats. PMID:27527211
Use of the "Exposome" in the Practice of Epidemiology: A Primer on -Omic Technologies. PMID:27519539
Membranome: a database for proteome-wide analysis of single-pass membrane proteins. PMID:27510400
Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health. PMID:27507964
High-Resolution Metabolomics Assessment of Military Personnel: Evaluating Analytical Strategies for Chemical Detection. PMID:27501105
Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel. PMID:27501104
Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics. PMID:27501099
Animal-Free Chemical Safety Assessment. PMID:27493630
Revealing disease-associated pathways by network integration of untargeted metabolomics. PMID:27479327
Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics. PMID:27471436
Changes in the Metabolome in Response to Low-Dose Exposure to Environmental Chemicals Used in Personal Care Products during Different Windows of Susceptibility. PMID:27467775
Prediction and diagnosis of renal cell carcinoma using nuclear magnetic resonance-based serum metabolomics and self-organizing maps. PMID:27463020
Getting the most out of PubChem for virtual screening. PMID:27454129
Clinical Metabolomics: The New Metabolic Window for Inborn Errors of Metabolism Investigations in the Post-Genomic Era. PMID:27447622
Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists. PMID:27439119
Preterm neonatal urinary renal developmental and acute kidney injury metabolomic profiling: an exploratory study. PMID:27435284
Metabolic Profiles of Obesity in American Indians: The Strong Heart Family Study. PMID:27434237
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue. PMID:27414759
Metabolites Associated With Malnutrition in the Intensive Care Unit Are Also Associated With 28-Day Mortality. PMID:27406941
Metabolite profiling of Dioscorea (yam) species reveals underutilised biodiversity and renewable sources for high-value compounds. PMID:27385275
Biomonitoring in the Era of the Exposome. PMID:27385067
Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans. PMID:27378919
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins. PMID:27374120
Evaluation of coverage, retention patterns, and selectivity of seven liquid chromatographic methods for metabolomics. PMID:27370688
Pharmacometabonomic Prediction of Busulfan Clearance in Hematopoetic Cell Transplant Recipients. PMID:27350098
Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources. PMID:27336457
The space of enzyme regulation in HeLa cells can be inferred from its intracellular metabolome. PMID:27335086
Assessment of Saliva as a Potential Biofluid for Biodosimetry: A Pilot Metabolomics Study in Mice. PMID:27332953
Plasma metabolomic analysis of human hepatocellular carcinoma: Diagnostic and therapeutic study. PMID:27322079
Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge. PMID:27306312
Computational approaches in target identification and drug discovery. PMID:27293534
Literature information in PubChem: associations between PubChem records and scientific articles. PMID:27293485
Omics databases on kidney disease: where they can be found and how to benefit from them. PMID:27274817
Metabolic rewiring in melanoma. PMID:27270434
A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury. PMID:27265840
The Importance of the Biological Impact of Exposure to the Concept of the Exposome. PMID:27258438
Development of Database Assisted Structure Identification (DASI) Methods for Nontargeted Metabolomics. PMID:27258318
Metabolomic Analysis in Brain Research: Opportunities and Challenges. PMID:27252656
Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors. PMID:27240414
Protein Disulfide Levels and Lens Elasticity Modulation: Applications for Presbyopia. PMID:27233034
The use of mass spectrometry for analysing metabolite biomarkers in epidemiology: methodological and statistical considerations for application to large numbers of biological samples. PMID:27230258
Metabolism, Metabolomics, and Nutritional Support of Patients with Sepsis. PMID:27229648
Putative role of the H(+)/sucrose symporter SLC45A3 as an osmolyte transporter in the kidney. PMID:27228996
Covariation Analysis of Serumal and Urinary Metabolites Suggests Aberrant Glycine and Fatty Acid Metabolism in Chronic Hepatitis B. PMID:27228119
Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients. PMID:27223119
Research Resources for Nuclear Receptor Signaling Pathways. PMID:27216565
NANS-mediated synthesis of sialic acid is required for brain and skeletal development. PMID:27213289
Metagenomics, Metatranscriptomics, and Metabolomics Approaches for Microbiome Analysis. PMID:27199545
Stress transgenerationally programs metabolic pathways linked to altered mental health. PMID:27188285
Insights on the virulence of swine respiratory tract mycoplasmas through genome-scale metabolic modeling. PMID:27178561
Whole Reproductive System Non-Negative Matrix Factorization Mass Spectrometry Imaging of an Early-Stage Ovarian Cancer Mouse Model. PMID:27159635
Metabolic Characterization of Advanced Liver Fibrosis in HCV Patients as Studied by Serum 1H-NMR Spectroscopy. PMID:27158896
Metabolomics: an emerging but powerful tool for precision medicine. PMID:27148576
Metabolic Profile and Root Development of Hypericum perforatum L. In vitro Roots under Stress Conditions Due to Chitosan Treatment and Culture Time. PMID:27148330
Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain. PMID:27142336
(1)H NMR- based metabolomics approaches as non- invasive tools for diagnosis of endometriosis. PMID:27141542
Chemical entity recognition in patents by combining dictionary-based and statistical approaches. PMID:27141091
Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A2 as a Regulator of Mitochondrial Bioenergetics during Activation. PMID:27133131
Advantages and Pitfalls of Mass Spectrometry Based Metabolome Profiling in Systems Biology. PMID:27128910
The omic approach to parasitic trematode research-a review of techniques and developments within the past 5 years. PMID:27126082
Non-target time trend screening: a data reduction strategy for detecting emerging contaminants in biological samples. PMID:27117254
Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis. PMID:27110360
Metabolic changes may precede proteostatic dysfunction in a Drosophila model of amyloid beta peptide toxicity. PMID:27103517
Omics Profiling in Precision Oncology. PMID:27099341
Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package. PMID:27096930
A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. PMID:27087910
MBROLE 2.0-functional enrichment of chemical compounds. PMID:27084944
Longitudinal Metabolite Profiling of Cerebrospinal Fluid in Normal Pressure Hydrocephalus Links Brain Metabolism with Exercise-Induced VEGF Production and Clinical Outcome. PMID:27084769
Discovery of Metabolic Biomarkers for Duchenne Muscular Dystrophy within a Natural History Study. PMID:27082433
Siderophore biosynthesis coordinately modulated the virulence-associated interactive metabolome of uropathogenic Escherichia coli and human urine. PMID:27076285
Circadian Time Structure of Circulating Plasma Lipid Components in Healthy Indians of Different Age Groups. PMID:27069330
Global Isotope Metabolomics Reveals Adaptive Strategies for Nitrogen Assimilation. PMID:27045776
Simultaneous Analysis of Major Coenzymes of Cellular Redox Reactions and Energy Using ex Vivo (1)H NMR Spectroscopy. PMID:27043450
Implications of genotypic differences in the generation of a urinary metabolomics radiation signature. PMID:27040378
Novel personalized pathway-based metabolomics models reveal key metabolic pathways for breast cancer diagnosis. PMID:27036109
Sheath flow SERS for chemical profiling in urine. PMID:27034996
Simultaneous detection of lysine metabolites by a single LC-MS/MS method: monitoring lysine degradation in mouse plasma. PMID:27026869
HNdb: an integrated database of gene and protein information on head and neck squamous cell carcinoma. PMID:27013077
Diagnostic 'omics' for active tuberculosis. PMID:27005907
Single-cell mass spectrometry with multi-solvent extraction identifies metabolic differences between left and right blastomeres in the 8-cell frog (Xenopus) embryo. PMID:27004603
Metabolomics: beyond biomarkers and towards mechanisms. PMID:26979502
Redox Imbalance Underlies the Fitness Defect Associated with Inactivation of the Pta-AckA Pathway in Staphylococcus aureus. PMID:26975873
Enabling Metabolomics Based Biomarker Discovery Studies Using Molecular Phenotyping of Exosome-Like Vesicles. PMID:26974972
Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes. PMID:26967252
NMRmix: A Tool for the Optimization of Compound Mixtures in 1D (1)H NMR Ligand Affinity Screens. PMID:26965640
Emerging applications of metabolomics in drug discovery and precision medicine. PMID:26965202
Prostate Cancer Associated Lipid Signatures in Serum Studied by ESI-Tandem Mass Spectrometryas Potential New Biomarkers. PMID:26958841
Diet, nutrition, and cancer: past, present and future. PMID:26951041
Cancer Metabolomics and the Human Metabolome Database. PMID:26950159
Metabolomics in rheumatic diseases: desperately seeking biomarkers. PMID:26935283
Integrated metabolomics and metagenomics analysis of plasma and urine identified microbial metabolites associated with coronary heart disease. PMID:26932197
Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication. PMID:26923630
Emerging new strategies for successful metabolite identification in metabolomics. PMID:26915807
Metabolomics-Based Discovery of Small Molecule Biomarkers in Serum Associated with Dengue Virus Infections and Disease Outcomes. PMID:26913918
A Computational Solution to Automatically Map Metabolite Libraries in the Context of Genome Scale Metabolic Networks. PMID:26909353
The Effect of Aqueous Extract of Cinnamon on the Metabolome of Plasmodium falciparum Using (1)HNMR Spectroscopy. PMID:26904134
Ion mobility mass spectrometry enhances low-abundance species detection in untargeted lipidomics. PMID:26900387
Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition. PMID:26898329
Using "Omics" and Integrated Multi-Omics Approaches to Guide Probiotic Selection to Mitigate Chytridiomycosis and Other Emerging Infectious Diseases. PMID:26870025
MetFrag relaunched: incorporating strategies beyond in silico fragmentation. PMID:26834843
Winners of CASMI2013: Automated Tools and Challenge Data. PMID:26819882
Generation of 2,000 breast cancer metabolic landscapes reveals a poor prognosis group with active serotonin production. PMID:26813959
Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins. PMID:26812040
Accelerating Adverse Outcome Pathway Development Using Publicly Available Data Sources. PMID:26809562
iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination. PMID:26784691
Development of an Optimized Protocol for NMR Metabolomics Studies of Human Colon Cancer Cell Lines and First Insight from Testing of the Protocol Using DNA G-Quadruplex Ligands as Novel Anti-Cancer Drugs. PMID:26784246
Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes. PMID:26783503
Unbiased Metabolomic Investigation of Alzheimer's Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism. PMID:26717242
Blood transcriptomics and metabolomics for personalized medicine. PMID:26702339
Understanding Metabolomics in Biomedical Research. PMID:26676338
A simple coculture system shows mutualism between anaerobic faecalibacteria and epithelial Caco-2 cells. PMID:26667159
NMR-Based Metabolomics Reveal a Recovery from Metabolic Changes in the Striatum of 6-OHDA-Induced Rats Treated with Basic Fibroblast Growth Factor. PMID:26650045
Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults. PMID:26626856
Nanoparticle-Assisted Removal of Protein in Human Serum for Metabolomics Studies. PMID:26605638
Plasma Metabolic Profiles in Women are Menopause Dependent. PMID:26580805
Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids. PMID:26573901
Flatography: Detection of gastrointestinal diseases by faecal gas analysis. PMID:26558144
MetaNetX/MNXref--reconciliation of metabolites and biochemical reactions to bring together genome-scale metabolic networks. PMID:26527720
Metabolomics profiling of pre-and post-anesthesia plasma samples of colorectal patients obtained via Ficoll separation. PMID:26491424
COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access. PMID:26491418
ECMDB 2.0: A richer resource for understanding the biochemistry of E. coli. PMID:26481353
ZINC 15--Ligand Discovery for Everyone. PMID:26479676
Metabolic responses induced by DNA damage and poly (ADP-ribose) polymerase (PARP) inhibition in MCF-7 cells. PMID:26478723
Can NMR solve some significant challenges in metabolomics? PMID:26476597
BiGG Models: A platform for integrating, standardizing and sharing genome-scale models. PMID:26476456
Developmental and Metabolic Plasticity of White-Skinned Grape Berries in Response to Botrytis cinerea during Noble Rot. PMID:26450706
Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation. PMID:26450397
Metabolic Profiling of Alpine and Ecuadorian Lichens. PMID:26437395
Right on TARGET: glutamine metabolism in cancer. PMID:26425657
Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected by Anaplasma phagocytophilum Infection in Tick Cells. PMID:26424601
Metabolomics in childhood diabetes. PMID:26420304
Toxic Markers of Matrine Determined Using (1) H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo. PMID:26413125
Searching molecular structure databases with tandem mass spectra using CSI:FingerID. PMID:26392543
The outer mucus layer hosts a distinct intestinal microbial niche. PMID:26392213
A multi-platform metabolomics approach identifies highly specific biomarkers of bacterial diversity in the vagina of pregnant and non-pregnant women. PMID:26387596
An overview of methods using (13)C for improved compound identification in metabolomics and natural products. PMID:26379677
Contribution of Colonic Fermentation and Fecal Water Toxicity to the Pathophysiology of Lactose-Intolerance. PMID:26371036
Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exposome Research. PMID:26358001
Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality. PMID:26352407
Metabolite profiling in retinoblastoma identifies novel clinicopathological subgroups. PMID:26348444
Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease. PMID:26342919
Phylogenetic and Metabolic Tracking of Gut Microbiota during Perinatal Development. PMID:26332837
Integration of 'omics' data in aging research: from biomarkers to systems biology. PMID:26331998
An Enlarged Profile of Uremic Solutes. PMID:26317986
Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics Simulations. PMID:26222615
Pharmacophore-based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell line. PMID:26220580
Data in support of enhancing metabolomics research through data mining. PMID:26217737
Lipid and Metabolic Changes in Rheumatoid Arthritis. PMID:26210510
High-Resolution Metabolomics: Review of the Field and Implications for Nursing Science and the Study of Preterm Birth. PMID:26183181
Targeted plasma metabolome response to variations in dietary glycemic load in a randomized, controlled, crossover feeding trial in healthy adults. PMID:26165375
Genetics of human metabolism: an update. PMID:26160913
Two elephants in the room: new hybrid nuclear magnetic resonance and mass spectrometry approaches for metabolomics. PMID:26154280
The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis. PMID:26121274
Repository of Human Blood Derivative Biospecimens in Biobank: Technical Implications. PMID:26106464
Metrabase: a cheminformatics and bioinformatics database for small molecule transporter data analysis and (Q)SAR modeling. PMID:26106450
Metabolic Consequences of Chronic Alcohol Abuse in Non-Smokers: A Pilot Study. PMID:26102199
Only one health, and so many omics. PMID:26101467
Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway. PMID:26097677
Analysis of the effect of the mitochondrial prohibitin complex, a context-dependent modulator of longevity, on the C. elegans metabolome. PMID:26092086
Untargeted Metabolomics Reveals Predominant Alterations in Lipid Metabolism Following Light Exposure in Broccoli Sprouts. PMID:26084047
Many InChIs and quite some feat. PMID:26081259
Mass Spectrometry-based Lipidomics and Its Application to Biomedical Research. PMID:26064851
Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline. PMID:26055719
kpath: integration of metabolic pathway linked data. PMID:26055101
QSAR Modeling Using Large-Scale Databases: Case Study for HIV-1 Reverse Transcriptase Inhibitors. PMID:26046311
Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome. PMID:26026149
Innovation in metabolomics to improve personalized healthcare. PMID:26014591
Computational Metabolomics Operations at BioCyc.org. PMID:26011592
Mass spectrometry tools and workflows for revealing microbial chemistry. PMID:25996313
SpeckTackle: JavaScript charts for spectroscopy. PMID:25984241
Prediction of intracellular metabolic states from extracellular metabolomic data. PMID:25972769
Dimethyl fumarate modulates antioxidant and lipid metabolism in oligodendrocytes. PMID:25967672
N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids. PMID:25964343
In-vitro suppression of IL-6 and IL-8 release from human pulmonary epithelial cells by non-anticoagulant fraction of enoxaparin. PMID:25961885
Mitochondrial responses to extreme environments: insights from metabolomics. PMID:25949809
The SwissLipids knowledgebase for lipid biology. PMID:25943471
Pathways with PathWhiz. PMID:25934797
Temperament type specific metabolite profiles of the prefrontal cortex and serum in cattle. PMID:25927228
PolySearch2: a significantly improved text-mining system for discovering associations between human diseases, genes, drugs, metabolites, toxins and more. PMID:25925572
The Da Vinci European BioBank: A Metabolomics-Driven Infrastructure. PMID:25913579
Effect of dietary sodium restriction on human urinary metabolomic profiles. PMID:25901092
MetaboAnalyst 3.0--making metabolomics more meaningful. PMID:25897128
Fact versus artifact: avoiding erroneous estimates of sulfated glycosaminoglycan content using the dimethylmethylene blue colorimetric assay for tissue-engineered constructs. PMID:25890595
Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach. PMID:25853295
Molecular crowding enhances facilitated diffusion of two human DNA glycosylases. PMID:25845592
Mass spectral similarity for untargeted metabolomics data analysis of complex mixtures. PMID:25844058
The application of HPLC and microprobe NMR spectroscopy in the identification of metabolites in complex biological matrices. PMID:25814271
Effect of Zn2+ binding and enzyme active site on the transition state for RNA 2'-O-transphosphorylation interpreted through kinetic isotope effects. PMID:25812974
Urinary (1)H-NMR-based metabolic profiling of children with NAFLD undergoing VSL#3 treatment. PMID:25809828
Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: fragmentation analysis for the classification and annotation of acylcarnitines. PMID:25806366
Analytical methods in untargeted metabolomics: state of the art in 2015. PMID:25798438
Open-access metabolomics databases for natural product research: present capabilities and future potential. PMID:25789275
Combining DI-ESI-MS and NMR datasets for metabolic profiling. PMID:25774104
Targeting of the hydrophobic metabolome by pathogens. PMID:25754025
A new paradigm for known metabolite identification in metabonomics/metabolomics: metabolite identification efficiency. PMID:25750701
A 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs. PMID:25750602
Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma. PMID:25749035
Intake of hydrolyzed casein is associated with reduced body fat accretion and enhanced phase II metabolism in obesity prone C57BL/6J mice. PMID:25738501
Biological databases for human research. PMID:25712261
Metabolic reprogramming in mutant IDH1 glioma cells. PMID:25706986
Pilot dietary intervention with heat-stabilized rice bran modulates stool microbiota and metabolites in healthy adults. PMID:25690418
Urine and serum metabolite profiling of rats fed a high-fat diet and the anti-obesity effects of caffeine consumption. PMID:25689639
Two dimensional NMR spectroscopic approaches for exploring plant metabolome: A review. PMID:25685540
Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome. PMID:25675482
Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model. PMID:25658945
Next-generation technologies for multiomics approaches including interactome sequencing. PMID:25649523
Physiologically based modeling of the pharmacokinetics of acetaminophen and its major metabolites in humans using a Bayesian population approach. PMID:25636597
Metabolomics in the developmental origins of obesity and its cardiometabolic consequences. PMID:25631626
Acute and chronic plasma metabolomic and liver transcriptomic stress effects in a mouse model with features of post-traumatic stress disorder. PMID:25629821
Regulation of mammalian nucleotide metabolism and biosynthesis. PMID:25628363
Metabolome profiling by HRMAS NMR spectroscopy of pheochromocytomas and paragangliomas detects SDH deficiency: clinical and pathophysiological implications. PMID:25622899
The emerging role of metabolomics in the development of biomarkers for pulmonary hypertension and other cardiovascular diseases (2013 Grover Conference series). PMID:25621155
Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by 1H-detected 15N nuclear magnetic resonance. PMID:25616249
Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients. PMID:25611149
Melancholic depression prediction by identifying representative features in metabolic and microarray profiles with missing values. PMID:25592604
Production of stable isotope-labeled acyl-coenzyme A thioesters by yeast stable isotope labeling by essential nutrients in cell culture. PMID:25572876
Pea fiber and wheat bran fiber show distinct metabolic profiles in rats as investigated by a 1H NMR-based metabolomic approach. PMID:25541729
Metabolic phenotyping for enhanced mechanistic stratification of chronic hepatitis C-induced liver fibrosis. PMID:25533003
Identification of metabolites from 2D (1)H-(13)C HSQC NMR using peak correlation plots. PMID:25511422
Autonomous metabolomics for rapid metabolite identification in global profiling. PMID:25496351
Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification. PMID:25495617
Pathomx: an interactive workflow-based tool for the analysis of metabolomic data. PMID:25490956
Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids. PMID:25486530
Expanding the limits of human blood metabolite quantitation using NMR spectroscopy. PMID:25485990
Novel metabolic markers for the risk of diabetes development in American Indians. PMID:25468946
Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS. PMID:25429371
CFam: a chemical families database based on iterative selection of functional seeds and seed-directed compound clustering. PMID:25414339
Sphingomyelin SM(d18:1/18:0) is significantly enhanced in cerebrospinal fluid samples dichotomized by pathological amyloid-β42, tau, and phospho-tau-181 levels. PMID:25408209
The impact of free or standardized lifestyle and urine sampling protocol on metabolome recognition accuracy. PMID:25403096
The use of metabolomics in population-based research. PMID:25398741
CeCaFDB: a curated database for the documentation, visualization and comparative analysis of central carbon metabolic flux distributions explored by 13C-fluxomics. PMID:25392417
Bioinformatics: the next frontier of metabolomics. PMID:25389922
Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention. PMID:25388013
Current advances in systems and integrative biology. PMID:25379142
T3DB: the toxic exposome database. PMID:25378312
Super Natural II--a database of natural products. PMID:25300487
Guanine-centric self-assembly of nucleotides in water: an important consideration in prebiotic chemistry. PMID:25285982
Systems biology analysis of omeprazole therapy in cirrhosis demonstrates significant shifts in gut microbiota composition and function. PMID:25258407
Exploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platforms. PMID:25237861
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia. PMID:25228990
Identification of low-dose responsive metabolites in X-irradiated human B lymphoblastoid cells and fibroblasts. PMID:25227127
Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer. PMID:25225614
TMDB: a literature-curated database for small molecular compounds found from tea. PMID:25224438
Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus. PMID:25224006
Prioritizing candidate disease metabolites based on global functional relationships between metabolites in the context of metabolic pathways. PMID:25153931
Metabolic phenotyping reveals a lipid mediator response to ionizing radiation. PMID:25126707
Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics. PMID:25120557
A new ion mobility-linear ion trap instrument for complex mixture analysis. PMID:25068446
Molecular docking simulations provide insights in the substrate binding sites and possible substrates of the ABCC6 transporter. PMID:25062064
Use of 1H-nuclear magnetic resonance to screen a set of biomarkers for monitoring metabolic disturbances in severe burn patients. PMID:25059459
A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry. PMID:25044893
Network thermodynamic curation of human and yeast genome-scale metabolic models. PMID:25028891
Transient and persistent metabolomic changes in plasma following chronic cigarette smoke exposure in a mouse model. PMID:25007263
Metabolomics for biomarker discovery in gastroenterological cancer. PMID:25003943
Metabolomics analysis identifies intestinal microbiota-derived biomarkers of colonization resistance in clindamycin-treated mice. PMID:24988418
Biochemical assessment of red blood cells during storage by (1)H nuclear magnetic resonance spectroscopy. Identification of a biomarker of their level of protection against oxidative stress. PMID:24960643
Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth. PMID:24958876
Applications of NMR in dairy research. PMID:24958391
1H NMR Analysis of Cerebrospinal Fluid from Alzheimer's Disease Patients: An Example of a Possible Misinterpretation Due to Non-Adjustment of pH. PMID:24958390
CASMI-The Small Molecule Identification Process from a Birmingham Perspective. PMID:24957998
Post-acquisition data processing for the screening of transformation products of different organic contaminants. Two-year monitoring of river water using LC-ESI-QTOF-MS and GCxGC-EI-TOF-MS. PMID:24952251
Tools and databases of the KOMICS web portal for preprocessing, mining, and dissemination of metabolomics data. PMID:24949426
Impacts of the Callipyge mutation on ovine plasma metabolites and muscle fibre type. PMID:24937646
Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose phosphate pathway in paraquat toxicity. PMID:24937102
Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). PMID:24901537
CFM-ID: a web server for annotation, spectrum prediction and metabolite identification from tandem mass spectra. PMID:24895432
Challenges in accurate quantitation of lysophosphatidic acids in human biofluids. PMID:24872406
Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry. PMID:24858467
A metabolomic approach to animal vitreous humor topographical composition: a pilot study. PMID:24845217
Alkemio: association of chemicals with biomedical topics by text and data mining. PMID:24838570
Metabolomic strategies for the identification of new enzyme functions and metabolic pathways. PMID:24829223
Integrating omics technologies to study pulmonary physiology and pathology at the systems level. PMID:24802001
Mass spectrometry of natural products: current, emerging and future technologies. PMID:24801551
Metabolic profiles of biological aging in American Indians: the Strong Heart Family Study. PMID:24799415
Statistical HOmogeneous Cluster SpectroscopY (SHOCSY): an optimized statistical approach for clustering of ¹H NMR spectral data to reduce interference and enhance robust biomarkers selection. PMID:24773160
A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice. PMID:24760204
On InChI and evaluating the quality of cross-reference links. PMID:24742140
Neurorestorative targets of dietary long-chain omega-3 fatty acids in neurological injury. PMID:24740740
Metabolomics in nutritional epidemiology: identifying metabolites associated with diet and quantifying their potential to uncover diet-disease relations in populations. PMID:24740205
Applying metabolomics to uncover novel biology in ARDS. PMID:24727586
Lactobacillus acidophilus NCFM affects vitamin E acetate metabolism and intestinal bile acid signature in monocolonized mice. PMID:24717228
NMR-Based Metabonomic Studies on Stomach Heat and Cold Syndromes and Intervention Effects of the Corresponding Formulas. PMID:24701240
Metabolomics network characterization of resuscitation after normocapnic hypoxia in a newborn piglet model supports the hypothesis that room air is better. PMID:24696864
Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans. PMID:24690587
How Gene Networks Can Uncover Novel CVD Players. PMID:24683432
The blood exposome and its role in discovering causes of disease. PMID:24659601
Ion mobility derived collision cross sections to support metabolomics applications. PMID:24640936
Plasma and serum lipidomics of healthy white adults shows characteristic profiles by subjects' gender and age. PMID:24632803
The intestinal metabolome: an intersection between microbiota and host. PMID:24631493
A nano ultra-performance liquid chromatography-high resolution mass spectrometry approach for global metabolomic profiling and case study on drug-resistant multiple myeloma. PMID:24611431
Comparing the Chemical Structure and Protein Content of ChEMBL, DrugBank, Human Metabolome Database and the Therapeutic Target Database. PMID:24533037
Comparative evaluation of open source software for mapping between metabolite identifiers in metabolic network reconstructions: application to Recon 2. PMID:24468196
Signal intensities derived from different NMR probes and parameters contribute to variations in quantification of metabolites. PMID:24465670
Candidate mediators of chondrocyte mechanotransduction via targeted and untargeted metabolomic measurements. PMID:24440608
Design and experimental approach to the construction of a human signal-molecule-profiling database. PMID:24351788
Metabolomics of the tumor microenvironment in pediatric acute lymphoblastic leukemia. PMID:24349380
A new specific succinate-glutamate metabolomic hallmark in SDHx-related paragangliomas. PMID:24312232
A machine-learned predictor of colonic polyps based on urinary metabolomics. PMID:24307992
Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteria. PMID:24303782
Isotopic ratio outlier analysis global metabolomics of Caenorhabditis elegans. PMID:24274725
Reconstruction and analysis of human kidney-specific metabolic network based on omics data. PMID:24222897
DrugBank 4.0: shedding new light on drug metabolism. PMID:24203711
SMPDB 2.0: big improvements to the Small Molecule Pathway Database. PMID:24203708
Metabolomics as a diagnostic tool in gastroenterology. PMID:24199025
RAMSY: ratio analysis of mass spectrometry to improve compound identification. PMID:24168717
Two birds with one stone: doing metabolomics with your proteomics kit. PMID:24155035
Molecular degradation of ancient documents revealed by 1H HR-MAS NMR spectroscopy. PMID:24104201
Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content. PMID:24103452
Review of mass spectrometry-based metabolomics in cancer research. PMID:24096148
Temporal metabolic profiling of plasma during endotoxemia in humans. PMID:24089011
Metabolic profiling framework for discovery of candidate diagnostic markers of malaria. PMID:24067624
Small molecules present in the cerebrospinal fluid metabolome influence superoxide dismutase 1 aggregation. PMID:24048249
The evolution of genome-scale models of cancer metabolism. PMID:24027532
Molecular networking as a dereplication strategy. PMID:24025162
The human urine metabolome. PMID:24023812
In silico enzymatic synthesis of a 400,000 compound biochemical database for nontargeted metabolomics. PMID:23991755
metabolicMine: an integrated genomics, genetics and proteomics data warehouse for common metabolic disease research. PMID:23935057
Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery. PMID:23892182
An analysis of a 'community-driven' reconstruction of the human metabolic network. PMID:23888127
Estrogen pathway polymorphisms in relation to primary open angle glaucoma: an analysis accounting for gender from the United States. PMID:23869166
Applications of metabolomics in cancer research. PMID:23858297
Bioinformatics for spermatogenesis: annotation of male reproduction based on proteomics. PMID:23852026
Technology platform development for targeted plasma metabolites in human heart failure. PMID:23826926
Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy. PMID:23826159
Metabolomics in the studies of islet autoimmunity and type 1 diabetes. PMID:23804263
Emerging applications of metabolomics in studying chemopreventive phytochemicals. PMID:23794098
Toward new biomarkers of cardiometabolic diseases. PMID:23770128
Mechanism of aflatoxin uptake in roots of intact groundnut (Arachis hypogaea L.) seedlings. PMID:23660803
Metabolomics reveals aging-associated attenuation of noninvasive radiation biomarkers in mice: potential role of polyamine catabolism and incoherent DNA damage-repair. PMID:23586774
A pathway approach to investigate the function and regulation of SREBPs. PMID:23516131
HMDB: the Human Metabolome Database PubMed citations: 935.

935 articles citing: HMDB: the Human Metabolome Database

Theaflavin 3-gallate inhibits the main protease (Mpro) of SARS-CoV-2 and reduces its count in vitro. PMID:35908093
From target analysis to suspect and non-target screening of endocrine-disrupting compounds in human urine. PMID:35904524
Protein-Ligand Docking in the Machine-Learning Era. PMID:35889440
Trans- and Multigenerational Maternal Social Isolation Stress Programs the Blood Plasma Metabolome in the F3 Generation. PMID:35888696
Novelty detection for metabolic dynamics established on breast cancer tissue using 2D NMR TOCSY spectra. PMID:35782733
Therapeutic Effect of Buyang Huanwu Decoction on the Gut Microbiota and Hippocampal Metabolism in a Rat Model of Cerebral Ischemia. PMID:35774407
Determination of Intra- and Extracellular Metabolic Adaptations of 3D Cell Cultures upon Challenges in Real-Time by NMR. PMID:35743000
Advances in Metabolomics-Driven Diagnostic Breeding and Crop Improvement. PMID:35736444
Lactiplantibacillus plantarum P9 improved gut microbial metabolites and alleviated inflammatory response in pesticide exposure cohorts. PMID:35733791
Next Generation Risk Assessment of the Anti-Androgen Flutamide Including the Contribution of Its Active Metabolite Hydroxyflutamide. PMID:35722059
Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Candida auris Metabolites. PMID:35674952
Intracellular Acetyl CoA Potentiates the Therapeutic Efficacy of Antitumor CD8+ T Cells. PMID:35648389
The Potential of Sewage Sludge to Predict and Evaluate the Human Chemical Exposome. PMID:35647215
Urinary metabolic modulation in human participants residing in Siachen: a 1H NMR metabolomics approach. PMID:35641596
Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice. PMID:35629884
First-Void Urine Microbiome in Women with Chlamydia trachomatis Infection. PMID:35628436
Recent Trends of Microbiota-Based Microbial Metabolites Metabolism in Liver Disease. PMID:35615096
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. PMID:35589701
Self-Adhesive and Antioxidant Poly(vinylpyrrolidone)/Alginate-Based Bilayer Films Loaded with Malva sylvestris Extracts as Potential Skin Dressings. PMID:35583459
The N-Terminus of Human Sulfotransferase 2B1b─a Sterol-Sensing Allosteric Site. PMID:35523209
The sustainable cycle of a new cacao-based bioplastic: from manufacturing to exploitable biodegradation products. PMID:35480269
Metabolomics Fingerprint Predicts Risk of Death in Dilated Cardiomyopathy and Heart Failure. PMID:35463749
Effect of Long-Term Potato Starch Retention with Citric Acid on Its Properties. PMID:35458652
Endo- and Exometabolome Crosstalk in Mesenchymal Stem Cells Undergoing Osteogenic Differentiation. PMID:35455937
Prenatal Supplementation in Beef Cattle and Its Effects on Plasma Metabolome of Dams and Calves. PMID:35448533
Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice. PMID:35448524
Lipidomics in Understanding Pathophysiology and Pharmacologic Effects in Inflammatory Diseases: Considerations for Drug Development. PMID:35448520
Effects of exercise on NAFLD using non-targeted metabolomics in adipose tissue, plasma, urine, and stool. PMID:35444259
Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions. PMID:35428194
Sea Cucumber Body Vesicular Syndrome Is Driven by the Pond Water Microbiome via an Altered Gut Microbiota. PMID:35418244
Goslin 2.0 Implements the Recent Lipid Shorthand Nomenclature for MS-Derived Lipid Structures. PMID:35404045
Comparative metabolomics provides novel insights into the basis of petiole color differences in celery (Apiumgraveolens L.). PMID:35403385
Providing Adverse Outcome Pathways from the AOP-Wiki in a Semantic Web Format to Increase Usability and Accessibility of the Content. PMID:35388368
Fluxomics - New Metabolomics Approaches to Monitor Metabolic Pathways. PMID:35387341
A multi-omics approach to elucidate the mechanisms of action of a dietary muramidase administered to broiler chickens. PMID:35365750
Expanding biochemical knowledge and illuminating metabolic dark matter with ATLASx. PMID:35322036
Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines. PMID:35315332
Transition of Dephospho-DctD to the Transcriptionally Active State via Interaction with Dephospho-IIAGlc. PMID:35311533
Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery. PMID:35305174
Comprehensive biomarker profiles and chemometric filtering of urinary metabolomics for effective discrimination of prostate carcinoma from benign hyperplasia. PMID:35288652
Blood pressure interactions with the DASH dietary pattern, sodium, and potassium: The International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP). PMID:35285859
Metabolomic Impact of Lidocaine on a Triple Negative Breast Cancer Cell Line. PMID:35273500
Integrated Metabolomics and Lipidomics Reveal High Accumulation of Glycerophospholipids in Human Astrocytes under the Lipotoxic Effect of Palmitic Acid and Tibolone Protection. PMID:35269616
Application of omics in hypertension and resistant hypertension. PMID:35264783
Mapping the Influence of the Gut Microbiota on Small Molecules across the Microbiome Gut Brain Axis. PMID:35262356
The Potential of Metabolomics in Biomedical Applications. PMID:35208267
Metabolomic Analysis Reveals Nutritional Diversity among Three Staple Crops and Three Fruits. PMID:35206028
Acute aerobic exercise reveals that FAHFAs distinguish the metabolomes of overweight and normal-weight runners. PMID:35192550
A mechanistic modeling framework reveals the key principles underlying tumor metabolism. PMID:35148308
Chemical Cartography Approaches to Study Trypanosomatid Infection. PMID:35129167
Metabolomics in endometriosis: challenges and perspectives for future studies. PMID:35128453
Oral Bacteriotherapy Reduces the Occurrence of Chronic Fatigue in COVID-19 Patients. PMID:35096923
Preclinical Evaluation of Dimethyl Itaconate Against Hepatocellular Carcinoma via Activation of the e/iNOS-Mediated NF-κB-Dependent Apoptotic Pathway. PMID:35095533
Knowledge-Driven Approaches to Create the MTox700+ Metabolite Panel for Predicting Toxicity. PMID:35094093
Metabolomic Profiles of the Creeping Wood Sorrel Oxalis corniculata in Radioactively Contaminated Fields in Fukushima: Dose-Dependent Changes in Key Metabolites. PMID:35054508
Marine Neurotoxins' Effects on Environmental and Human Health: An OMICS Overview. PMID:35049872
Breath biomarkers of insulin resistance in pre-diabetic Hispanic adolescents with obesity. PMID:35013420
Maternal regulation of biliary disease in neonates via gut microbial metabolites. PMID:35013245
Gut Microbiota as a Source of Uremic Toxins. PMID:35008909
HMDB 5.0: the Human Metabolome Database for 2022. PMID:34986597
Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics. PMID:34959746
High-Fructose Diet Alters Intestinal Microbial Profile and Correlates with Early Tumorigenesis in a Mouse Model of Barrett's Esophagus. PMID:34946037
Advances in Analyzing the Breast Cancer Lipidome and Its Relevance to Disease Progression and Treatment. PMID:34914014
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. PMID:34900668
Understanding host-microbiota interactions in the commercial piglet around weaning. PMID:34873196
High-Quality Genome-Scale Reconstruction of Corynebacterium glutamicum ATCC 13032. PMID:34867870
A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation. PMID:34858137
Bacterial challenge-associated metabolic phenotypes in Hermetia illucens defining nutritional and functional benefits. PMID:34857836
Understanding the Mechanism of Action of NAI-112, a Lanthipeptide with Potent Antinociceptive Activity. PMID:34833857
Urinary Volatiles and Chemical Characterisation for the Non-Invasive Detection of Prostate and Bladder Cancers. PMID:34821653
Metabolomic and lipidomic characterization of an X-chromosome deletion disorder in neural progenitor cells by UHPLC-HRMS. PMID:34820667
Screening of Altered Metabolites and Metabolic Pathways in Celiac Disease Using NMR Spectroscopy. PMID:34820452
Predicting lupus membranous nephritis using reduced picolinic acid to tryptophan ratio as a urinary biomarker. PMID:34805802
Multivariate classification techniques and mass spectrometry as a tool in the screening of patients with fibromyalgia. PMID:34799667
A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria. PMID:34799606
Assessment of metabolic perturbations associated with exposure to phthalates among pregnant African American women. PMID:34793805
Metabolite Identification Using Infrared Ion Spectroscopy─Novel Biomarkers for Pyridoxine-Dependent Epilepsy. PMID:34756024
mapMECFS: a portal to enhance data discovery across biological disciplines and collaborative sites. PMID:34749736
Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice. PMID:34707105
Pharmacometabolomics by NMR in Oncology: A Systematic Review. PMID:34681239
PaIRKAT: A pathway integrated regression-based kernel association test with applications to metabolomics and COPD phenotypes. PMID:34679079
Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective. PMID:34660833
A metabolome atlas of the aging mouse brain. PMID:34654818
NCATS Inxight Drugs: a comprehensive and curated portal for translational research. PMID:34648031
Finger sweat analysis enables short interval metabolic biomonitoring in humans. PMID:34645808
Glutamine restores mitochondrial respiration in bleomycin-injured epithelial cells. PMID:34634441
Investigation of the Geographical Environment Impact on the Chemical Components of Peganum harmala L. through a Combined Analytical Method. PMID:34632207
A survey on computational methods in discovering protein inhibitors of SARS-CoV-2. PMID:34623382
Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease. PMID:34606502
Metabolomic Response of the Creeping Wood Sorrel Oxalis corniculata to Low-Dose Radiation Exposure from Fukushima's Contaminated Soil. PMID:34575139
Non-Targeted LC-MS Metabolomics Approach towards an Authentication of the Geographical Origin of Grain Maize (Zea mays L.) Samples. PMID:34574275
Why Has Metabolomics So Far Not Managed to Efficiently Contribute to the Improvement of Assisted Reproduction Outcomes? The Answer through a Review of the Best Available Current Evidence. PMID:34573944
Lipid Metabolite Biomarkers in Cardiovascular Disease: Discovery and Biomechanism Translation from Human Studies. PMID:34564437
Metabolomics-Based Screening of Inborn Errors of Metabolism: Enhancing Clinical Application with a Robust Computational Pipeline. PMID:34564390
Deuterium Metabolic Imaging-Rediscovery of a Spectroscopic Tool. PMID:34564385
Peak learning of mass spectrometry imaging data using artificial neural networks. PMID:34545087
Microbial Diversity and Non-volatile Metabolites Profile of Low-Temperature Sausage Stored at Room Temperature. PMID:34512589
Sarcopenic metabolomic profile reflected a sarcopenic phenotype associated with amino acid and essential fatty acid changes. PMID:34498155
Machine learning approaches to predict gestational age in normal and complicated pregnancies via urinary metabolomics analysis. PMID:34493809
Tooth biomarkers to characterize the temporal dynamics of the fetal and early-life exposome. PMID:34482270
Food Composition Databases: Does It Matter to Human Health? PMID:34444976
Expanding Urinary Metabolite Annotation through Integrated Mass Spectral Similarity Networking. PMID:34436864
Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests. PMID:34432105
IBD metabonomics predicts phenotype, disease course, and treatment response. PMID:34419930
Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose. PMID:34414480
Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior. PMID:34381081
Absorption Coefficients of Phenolic Structures in Different Solvents Routinely Used for Experiments. PMID:34361808
LipiDisease: associate lipids to diseases using literature mining. PMID:34358314
In Situ Metabolomics Expands the Spectrum of Renal Tumours Positive on 99mTc-sestamibi Single Photon Emission Computed Tomography/Computed Tomography Examination. PMID:34337482
Impact of Weaning and Maternal Immune Activation on the Metabolism of Pigs. PMID:34336923
Clitorienolactones and Isoflavonoids of Clitorea ternatea Roots Alleviate Stress-Like Symptoms in a Reserpine-Induced Zebrafish Model. PMID:34299411
An integrated transcriptome and metabolome approach reveals the accumulation of taste-related metabolites and gene regulatory networks during watermelon fruit development. PMID:34292405
Computational strategies for the discovery of biological functions of health foods, nutraceuticals and cosmeceuticals: a review. PMID:34258685
Transcriptome and metabolome analyses of cold and darkness-induced pellicle cysts of Scrippsiella trochoidea. PMID:34246248
Coupling proteomics and metabolomics for the unsupervised identification of protein-metabolite interactions in Chaetomium thermophilum. PMID:34242379
Inter-kingdom relationships in Crohn's disease explored using a multi-omics approach. PMID:34241567
A two-stage computational approach to predict novel ligands for a chemosensory receptor. PMID:34235481
NFnetFu: A novel workflow for microbiome data fusion. PMID:34216888
Metabolomic Profiling of Pregnancies With Polycystic Ovary Syndrome Identifies a Unique Metabolic Signature and Potential Predictive Biomarkers of Low Birth Weight. PMID:34211435
Effects of a Diet Based on Foods from Symbiotic Agriculture on the Gut Microbiota of Subjects at Risk for Metabolic Syndrome. PMID:34204572
Metabolic Dynamics in Short- and Long-Term Microgravity in Human Primary Macrophages. PMID:34201720
Untargeted Metabolomics and Antioxidant Capacities of Muscadine Grape Genotypes during Berry Development. PMID:34200012
Fibrinogen activates focal adhesion kinase (FAK) promoting colorectal adenocarcinoma growth. PMID:34192410
Evolving scenario of big data and Artificial Intelligence (AI) in drug discovery. PMID:34159484
MolDiscovery: learning mass spectrometry fragmentation of small molecules. PMID:34140479
Nontargeted Metabolomic Analysis of Plasma Metabolite Changes in Patients with Adolescent Idiopathic Scoliosis. PMID:34121924
Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics. PMID:34103421
A novel, multitargeted endogenous metabolic modulator composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models. PMID:34088912
High-resolution metabolomic biomarkers for lung cancer diagnosis and prognosis. PMID:34083687
Unsupervised logic-based mechanism inference for network-driven biological processes. PMID:34077417
Glioblastoma Metabolomics-In Vitro Studies. PMID:34068300
Dysregulation of Glycerophosphocholines in the Cutaneous Lesion Caused by Leishmania major in Experimental Murine Models. PMID:34068119
1H NMR based metabolic profiling distinguishes the differential impact of capture techniques on wild bighorn sheep. PMID:34050238
Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions. PMID:34043632
The Effects of Sampling and Storage Conditions on the Metabolite Profile of the Marine Sponge Geodia barretti. PMID:34041223
Isobutyrylcarnitine as a Biomarker of OCT1 Activity and Interspecies Differences in its Membrane Transport. PMID:34040533
A new technological approach in diagnostic pathology: mass spectrometry imaging-based metabolomics for biomarker detection in urachal cancer. PMID:34021261
PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease. PMID:34004162
Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance. PMID:33976213
Marine Community Metabolomes Carry Fingerprints of Phytoplankton Community Composition. PMID:33947800
Quo Vadis Caenorhabditis elegans Metabolomics-A Review of Current Methods and Applications to Explore Metabolism in the Nematode. PMID:33947148
Inheritable testicular metabolic memory of high-fat diet causes transgenerational sperm defects in mice. PMID:33941835
Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain. PMID:33939923
Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition. PMID:33926456
Precision Oncology via NMR-Based Metabolomics: A Review on Breast Cancer. PMID:33925233
Clinical Insights into Mitochondrial Neurodevelopmental and Neurodegenerative Disorders: Their Biosignatures from Mass Spectrometry-Based Metabolomics. PMID:33920115
Plasma Metabolome and Lipidome Associations with Type 2 Diabetes and Diabetic Nephropathy. PMID:33918080
Differential Metabolome in Rheumatoid Arthritis: a Brief Perspective. PMID:33913028
Urinary Metabolomic and Proteomic Analyses in a Mouse Model of Prostatic Inflammation. PMID:33870183
An Integrative In Silico Mathematical Modelling Study of The Anti-Cancer Effect of Clove Extract ( Syzygium aromaticum ) Combined with In Vitro Metabolomics Study Using 1HNMR Spectroscopy. PMID:33850939
NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. PMID:33843271
Towards Extending the Detection Window of Gamma-Hydroxybutyric Acid-An Untargeted Metabolomics Study in Serum and Urine Following Controlled Administration in Healthy Men. PMID:33809281
SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome. PMID:33807773
Tracking the Progression of Triple Negative Mammary Tumors over Time by Chemometric Analysis of Urinary Volatile Organic Compounds. PMID:33806757
Sirtuins-Mediated System-Level Regulation of Mammalian Tissues at the Interface between Metabolism and Cell Cycle: A Systematic Review. PMID:33806509
Effect of Different Drying Methods on the Nutritional Value of Hibiscus sabdariffa Calyces as Revealed by NMR Metabolomics. PMID:33802805
NMR-Based Metabolomics in Cancer Research. PMID:33791984
Methods of Lipidomic Analysis: Extraction, Derivatization, Separation, and Identification of Lipids. PMID:33791982
Microbial Metabolomics: From Methods to Translational Applications. PMID:33791977
Mass Spectrometry-Based Shotgun Lipidomics for Cancer Research. PMID:33791973
Circulating blood metabolite trajectories and risk of rheumatoid arthritis among military personnel in the Department of Defense Biorepository. PMID:33753325
Adaptation of central metabolite pools to variations in growth rate and cultivation conditions in Saccharomyces cerevisiae. PMID:33750414
A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives. PMID:33741955
Early socialization and environmental enrichment of lactating piglets affects the caecal microbiota and metabolomic response after weaning. PMID:33731752
Ethanol Extract of Yak-Kong Fermented by Lactic Acid Bacteria from a Korean Infant Markedly Reduces Matrix Metallopreteinase-1 Expression Induced by Solar Ultraviolet Irradiation in Human Keratinocytes and a 3D Skin Model. PMID:33672035
Metabolomic and elemental profiling of human tissue in kidney cancer. PMID:33661419
Spatially Resolved Mass Spectrometry at the Single Cell: Recent Innovations in Proteomics and Metabolomics. PMID:33656885
Lipid profiling of mouse intestinal organoids for studying APC mutations. PMID:33620068
How Well Can Multivariate and Univariate GWAS Distinguish Between True and Spurious Pleiotropy? PMID:33584799
Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. PMID:33574263
Metabolic dysfunction in pregnancy: Fingerprinting the maternal metabolome using proton nuclear magnetic resonance spectroscopy. PMID:33532625
Metabotypes of Pseudomonas aeruginosa Correlate with Antibiotic Resistance, Virulence and Clinical Outcome in Cystic Fibrosis Chronic Infections. PMID:33494144
A dynamic multi-tissue model to study human metabolism. PMID:33483512
Virtual Screening of Natural Compounds as Potential PI3K-AKT1 Signaling Pathway Inhibitors and Experimental Validation. PMID:33477701
Non-targeted tandem mass spectrometry enables the visualization of organic matter chemotype shifts in coastal seawater. PMID:33460888
A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions. PMID:33431024
Use of Untargeted Metabolomics to Explore the Air Pollution-Related Disease Continuum. PMID:33420964
Optimization of metabolite extraction and analytical methods from shrimp intestine for metabolomics profile analysis using LC-HRMS/MS. PMID:33420663
Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes. PMID:33397942
Safety risk management for low molecular weight process-related impurities in monoclonal antibody therapeutics: Categorization, risk assessment, testing strategy, and process development with leveraging clearance potential. PMID:33373106
Targeted Isolation of Anti-Trypanosomal Naphthofuran-Quinone Compounds from the Mangrove Plant Avicennia lanata. PMID:33371387
Systems View of Deconditioning During Spaceflight Simulation in the PlanHab Project: The Departure of Urine 1 H-NMR Metabolomes From Healthy State in Young Males Subjected to Bedrest Inactivity and Hypoxia. PMID:33364971
Metabolome-wide association study of flavorant vanillin exposure in bronchial epithelial cells reveals disease-related perturbations in metabolism. PMID:33360165
Metabolomic and Transcriptomic Analysis of MCF-7 Cells Exposed to 23 Chemicals at Human-Relevant Levels: Estimation of Individual Chemical Contribution to Effects. PMID:33325755
Urinary metabolic phenotyping for Alzheimer's disease. PMID:33303834
Metabolic Signatures of Gestational Weight Gain and Postpartum Weight Loss in a Lifestyle Intervention Study of Overweight and Obese Women. PMID:33291639
A metabolomic study of cervical dystonia. PMID:33271463
Robustness and lethality in multilayer biological molecular networks. PMID:33247151
Variable Selection in Untargeted Metabolomics and the Danger of Sparsity. PMID:33213095
MFSD12 mediates the import of cysteine into melanosomes and lysosomes. PMID:33208952
Metabolomic Signatures in Pediatric Crohn's Disease Patients with Mild or Quiescent Disease Treated with Partial Enteral Nutrition: A Feasibility Study. PMID:33207993
Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats. PMID:33202669
Monitoring Methylmalonic Aciduria by NMR Urinomics. PMID:33202577
Sanitary Conditions Affect the Colonic Microbiome and the Colonic and Systemic Metabolome of Female Pigs. PMID:33195612
The utility of nuclear magnetic resonance spectroscopy in assisted reproduction. PMID:33142083
IMAGINE Network's Mind And Gut Interactions Cohort (MAGIC) Study: a protocol for a prospective observational multicentre cohort study in inflammatory bowel disease and irritable bowel syndrome. PMID:33087380
Emerging Role of Metabolomics in Ovarian Cancer Diagnosis. PMID:33086611
A Nuclear Magnetic Resonance (NMR) Platform for Real-Time Metabolic Monitoring of Bioprocesses. PMID:33066296
Most abundant metabolites in tissues of freshwater fish pike-perch (Sander lucioperca). PMID:33051472
NMR-Based Metabolomic Analysis and Microbial Composition of Soil Supporting Burkea africana Growth. PMID:33050369
137Cs γ Ray and 28Si Irradiation Induced Murine Hepatocellular Carcinoma Lipid Changes in Liver Assessed by MALDI-MSI Combined with Spatial Shrunken Centroid Clustering Algorithm: A Pilot Study. PMID:33043195
Qualitative Factor-Based Comparison of NMR, Targeted and Untargeted GC-MS and LC-MS on the Metabolomic Profiles of Rioja and Priorat Red Wines. PMID:33003509
GPR91 Receptor Mediates Protection against Doxorubicin-Induced Cardiotoxicity without Altering Its Anticancer Efficacy. An In Vitro Study on H9C2 Cardiomyoblasts and Breast Cancer-Derived MCF-7 Cells. PMID:32992522
Named Entity Recognition and Relation Detection for Biomedical Information Extraction. PMID:32984300
Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery. PMID:32972433
Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data. PMID:32967365
Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti. PMID:32948809
Flavonoids as Potential anti-MRSA Agents through Modulation of PBP2a: A Computational and Experimental Study. PMID:32878266
Multi-omics analysis to examine microbiota, host gene expression and metabolites in the intestine of black tiger shrimp (Penaeus monodon) with different growth performance. PMID:32864208
Metabolomics in Radiation Biodosimetry: Current Approaches and Advances. PMID:32796693
Excretory/Secretory Metabolome of the Zoonotic Roundworm Parasite Toxocara canis. PMID:32781793
Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies. PMID:32780286
Mass spectrometry imaging as a potential technique for diagnostic of Huanglongbing disease using fast and simple sample preparation. PMID:32778716
Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance. PMID:32763164
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. PMID:32762776
Metabolic response of blood vessels to TNFα. PMID:32749215
A period of 10 weeks of increased protein consumption does not alter faecal microbiota or volatile metabolites in healthy older men: a randomised controlled trial. PMID:32742642
Evaluating a targeted multiple reaction monitoring approach to global untargeted lipidomic analyses of human plasma. PMID:32738001
Comparative Untargeted Metabolomics Analysis of the Psychostimulants 3,4-Methylenedioxy-Methamphetamine (MDMA), Amphetamine, and the Novel Psychoactive Substance Mephedrone after Controlled Drug Administration to Humans. PMID:32726975
Transcriptomic and Metabolic Responses to a Live-Attenuated Francisella tularensis Vaccine. PMID:32722194
Biomarkers of radiation-induced vascular injury. PMID:32721134
Determination of Tryptophan Metabolites in Serum and Cerebrospinal Fluid Samples Using Microextraction by Packed Sorbent, Silylation and GC-MS Detection. PMID:32708889
NMR-Based Metabolomic Comparison of Brassica oleracea (Var. italica): Organic and Conventional Farming. PMID:32708866
Identification of metabolites associated with prostate cancer risk: a nested case-control study with long follow-up in the Northern Sweden Health and Disease Study. PMID:32698845
Plasma Phospholipid Metabolites Associate With Functional Outcomes Following Mild Traumatic Brain Injury in Older Adults. PMID:32696677
Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling. PMID:32663517
Nuclear magnetic resonance and surface-assisted laser desorption/ionization mass spectrometry-based serum metabolomics of kidney cancer. PMID:32661677
A quest to identify suitable organic tracers for estimating children's dust ingestion rates. PMID:32661335
Cancer systems immunology. PMID:32657757
metPropagate: network-guided propagation of metabolomic information for prioritization of metabolic disease genes. PMID:32637154
Metabolomics of Milk Reflects a Negative Energy Balance in Cows. PMID:32633519
Ridinilazole, a narrow spectrum antibiotic for treatment of Clostridioides difficile infection, enhances preservation of microbiota-dependent bile acids. PMID:32597706
Goslin: A Grammar of Succinct Lipid Nomenclature. PMID:32589019
A longitudinal serum NMR-based metabolomics dataset of ischemia-reperfusion injury in adult cardiac surgery. PMID:32581368
The Zebra Mussel (Dreissena polymorpha) as a Model Organism for Ecotoxicological Studies: A Prior 1H NMR Spectrum Interpretation of a Whole Body Extract for Metabolism Monitoring. PMID:32570933
Harmonization of quality metrics and power calculation in multi-omic studies. PMID:32555183
Metabolomics as an Emerging Tool in the Search for Astrobiologically Relevant Biomarkers. PMID:32551936
1H Nuclear Magnetic Resonance of Pig Seminal Plasma Reveals Intra-Ejaculate Variation in Metabolites. PMID:32549232
Exploring the potential of laser desorption ionisation time-of-flight mass spectrometry to analyse organic capping agents on inorganic nanoparticle surfaces. PMID:32542454
The Bovine Metabolome. PMID:32517015
Multi-omics analysis on an agroecosystem reveals the significant role of organic nitrogen to increase agricultural crop yield. PMID:32513689
Therapeutic methods of gut microbiota modification in colorectal cancer management - fecal microbiota transplantation, prebiotics, probiotics, and synbiotics. PMID:32453670
NMR-based plasma metabolic profiling in patients with unstable angina. PMID:32440317
Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. PMID:32434918
Evaluation of Non-Uniform Sampling 2D 1H-13C HSQC Spectra for Semi-Quantitative Metabolomics. PMID:32429340
A Comparative Study of Rat Urine 1H-NMR Metabolome Changes Presumably Arising from Isoproterenol-Induced Heart Necrosis Versus Clarithromycin-Induced QT Interval Prolongation. PMID:32414184
Plant Dynamic Metabolic Response to Bacteriophage Treatment After Xanthomonas campestris pv. campestris Infection. PMID:32390981
Non-invasive Assessment of Fecal Stress Biomarkers in Hunting Dogs During Exercise and at Rest. PMID:32373631
A Metabolite Composite Score Attenuated a Substantial Portion of the Higher Mortality Risk Associated With Frailty Among Community-Dwelling Older Adults. PMID:32361748
The Urinary Metabolome of Healthy Newborns. PMID:32340350
Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula. PMID:32330237
Disease reciprocity between gingivitis and obesity. PMID:32329896
Higher Accumulation of Docosahexaenoic Acid in the Vermilion of the Human Lip than in the Skin. PMID:32316553
Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. PMID:32300895
Natural products: Designing Russian medications. PMID:32288428
Effects of Alternative Administration Programs of a Synbiotic Supplement on Broiler Performance, Foot Pad Dermatitis, Caecal Microbiota, and Blood Metabolites. PMID:32245036
Determination of Glyphosate in Dried Wheat by 1H-NMR Spectroscopy. PMID:32231040
Bile Acid Profile and its Changes in Response to Cefoperazone Treatment in MR1 Deficient Mice. PMID:32225042
Nuclear Magnetic Resonance to Detect Rumen Metabolites Associated with Enteric Methane Emissions from Beef Cattle. PMID:32221381
Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype. PMID:32184446
A Solution to Antifolate Resistance in Group B Streptococcus: Untargeted Metabolomics Identifies Human Milk Oligosaccharide-Induced Perturbations That Result in Potentiation of Trimethoprim. PMID:32184236
New markers for sepsis caused by Pseudomonas aeruginosa during burn infection. PMID:32170472
An Integrated Multi-Disciplinary Perspectivefor Addressing Challenges of the Human Gut Microbiome. PMID:32155792
New Insights About Doxorubicin-Induced Toxicity to Cardiomyoblast-Derived H9C2 Cells and Dexrazoxane Cytoprotective Effect: Contribution of In Vitro 1H-NMR Metabonomics. PMID:32153402
Gut microbiota-derived metabolites as key actors in inflammatory bowel disease. PMID:32076145
Targeting glioma-initiating cells via the tyrosine metabolic pathway. PMID:32059178
Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis. PMID:32025330
Cytosolic GLUTAMINE SYNTHETASE1;1 Modulates Metabolism and Chloroplast Development in Roots. PMID:32024696
Metabolomic Analysis of the Effects of Leptin Replacement Therapy in Patients with Lipodystrophy. PMID:32010873
Current Blockades of Proteins inside Nanopores for Real-Time Metabolome Analysis. PMID:32003969
Predicting octanol/water partition coefficients for the SAMPL6 challenge using the SM12, SM8, and SMD solvation models. PMID:32002781
Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models. PMID:32001719
Advanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystems. PMID:31992728
Prepregnant Obesity of Mothers in a Multiethnic Cohort Is Associated with Cord Blood Metabolomic Changes in Offspring. PMID:31975597
Metabolites Associated with Walking Ability Among the Oldest Old from the CHS All Stars Study. PMID:31970383
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction. PMID:31965747
Describing the fecal metabolome in cryogenically collected samples from healthy participants. PMID:31965056
A Metabolomic Study to Identify Potential Tissue Biomarkers for Indomethacin-Induced Gastric Ulcer in Rats. PMID:31908738
Biomarkers of meat and seafood intake: an extensive literature review. PMID:31908682
Omics Integration for Mitochondria Systems Biology. PMID:31891667
Proton NMR Enables the Absolute Quantification of Aqueous Metabolites and Lipid Classes in Unique Mouse Liver Samples. PMID:31877749
Integrative Metabolomic and Metallomic Analysis in a Case-Control Cohort With Parkinson's Disease. PMID:31866853
Emerging Insights into the Metabolic Alterations in Aging Using Metabolomics. PMID:31847272
Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification. PMID:31842810
Environmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice. PMID:31822602
The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain. PMID:31800589
Metabolome-Wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan. PMID:31800448
Untargeted Metabolomics-Based Screening Method for Inborn Errors of Metabolism using Semi-Automatic Sample Preparation with an UHPLC- Orbitrap-MS Platform. PMID:31779119
Contribution of Berry Polyphenols to the Human Metabolome. PMID:31757061
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. PMID:31722069
Infected chronic ischemic wound topically treated with a multi-strain probiotic formulation: a novel tailored treatment strategy. PMID:31706326
Influence of Drying Method on NMR-Based Metabolic Profiling of Human Cell Lines. PMID:31683565
Classifying the antibody-negative NMO syndromes: Clinical, imaging, and metabolomic modeling. PMID:31659123
Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics. PMID:31640247
Investigating the Protective Effect of Gross Saponins of Tribulus terrestris Fruit against Ischemic Stroke in Rat Using Metabolomics and Network Pharmacology. PMID:31640179
Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulation. PMID:31637787
An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs. PMID:31587113
Foamy Urine: Is This a Sign of Kidney Disease? PMID:31575619
Metabolic Effects of Dietary Glycerol Supplementation in Muscle and Liver of European Seabass and Rainbow Trout by 1H NMR Metabolomics. PMID:31569727
The metaRbolomics Toolbox in Bioconductor and beyond. PMID:31548506
A precision medicine approach to defining the impact of doxorubicin on the bioenergetic-metabolite interactome in human platelets. PMID:31546171
Uncovering sperm metabolome to discover biomarkers for bull fertility. PMID:31533629
Comparative metabolomics of MCF-7 breast cancer cells using different extraction solvents assessed by mass spectroscopy. PMID:31511569
In situ metabolomics of aldosterone-producing adenomas. PMID:31484828
Drivers of human gut microbial community assembly: coadaptation, determinism and stochasticity. PMID:31477821
Tools for Enhanced NMR-Based Metabolomics Analysis. PMID:31463858
Multiple "Omics" data-based biomarker screening for hepatocellular carcinoma diagnosis. PMID:31435173
Screening of Microbial Volatile Organic Compounds for Detection of Disease in Cattle: Development of Lab-scale Method. PMID:31431630
Evaluation of In Silico Multifeature Libraries for Providing Evidence for the Presence of Small Molecules in Synthetic Blinded Samples. PMID:31430141
Mass Spectrometry Fingerprints of Small-Molecule Metabolites in Biofluids: Building a Spectral Library of Recurrent Spectra for Urine Analysis. PMID:31424920
Metabolomic characterization of myocardial ischemia-reperfusion injury in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention. PMID:31409856
Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice. PMID:31408004
Bioactive Brominated Oxindole Alkaloids from the Red Sea Sponge Callyspongia siphonella. PMID:31395834
Crystal structure of zymonic acid and a redetermination of its precursor, pyruvic acid. PMID:31391982
Sulfadiazine Sodium Ameliorates the Metabolomic Perturbation in Mice Infected with Toxoplasma gondii. PMID:31383652
Insights into Computational Drug Repurposing for Neurodegenerative Disease. PMID:31326236
Correlations Between LC-MS/MS-Detected Glycomics and NMR-Detected Metabolomics in Caenorhabditis elegans Development. PMID:31316996
Predictive metabolomic profiling of microbial communities using amplicon or metagenomic sequences. PMID:31316056
Metabolomic Analysis Identifies Alterations of Amino Acid Metabolome Signatures in the Postmortem Brain of Alzheimer's Disease. PMID:31308797
Guava (Psidium guajava) Fruit Extract Prepared by Supercritical CO2 Extraction Inhibits Intestinal Glucose Resorption in a Double-Blind, Randomized Clinical Study. PMID:31277259
Effects of obesity on the lipid and metabolite profiles of young adults by serum 1H-NMR spectroscopy. PMID:31259100
NMR Spectroscopy for Metabolomics Research. PMID:31252628
The Effects of Age and Reproduction on the Lipidome of Caenorhabditis elegans. PMID:31249646
Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux. PMID:31236115
Metabolic Profiling of the Diabetic Heart: Toward a Richer Picture. PMID:31214041
NMR metabolome of Borrelia burgdorferi in vitro and in vivo in mice. PMID:31142787
Metabolomics Studies To Decipher Stress Responses in Mycobacterium smegmatis Point to a Putative Pathway of Methylated Amine Biosynthesis. PMID:31138627
Metabolomic Strategies in Biomarker Research-New Approach for Indirect Identification of Drug Consumption and Sample Manipulation in Clinical and Forensic Toxicology? PMID:31134189
Metabolome Wide Association Study of Serum Poly and Perfluoroalkyl Substances (PFASs) in Pregnancy and Early Postpartum. PMID:31121237
Continuous in vivo Metabolism by NMR. PMID:31114791
13C Labeling of Nematode Worms to Improve Metabolome Coverage by Heteronuclear Nuclear Magnetic Resonance Experiments. PMID:31106208
Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer's risk factors among 1,111 cohort participants. PMID:31104335
Metabolome Wide Association Study of serum DDT and DDE in Pregnancy and Early Postpartum. PMID:31102720
Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. PMID:31097699
Evaluating sub-lethal stress from Roundup® exposure in Artemia franciscana using 1H NMR and GC-MS. PMID:31077969
Extractive Ratio Analysis NMR Spectroscopy for Metabolite Identification in Complex Biological Mixtures. PMID:31059230
Metabolites Associated with Vigor to Frailty Among Community-Dwelling Older Black Men. PMID:31052232
Characterizing novel olfactory receptors expressed in the murine renal cortex. PMID:31042061
Review: Endogenously Produced Volatiles for In Vitro Toxicity Testing Using Cell Lines. PMID:31037250
Network Medicine in Pathobiology. PMID:31014954
Computational Methods for the Discovery of Metabolic Markers of Complex Traits. PMID:30987289
Biomarkers of tuber intake. PMID:30984301
Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice. PMID:30943218
Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data. PMID:30932478
Metabolic signatures suggest o-phosphocholine to UDP-N-acetylglucosamine ratio as a potential biomarker for high-glucose and/or palmitate exposure in pancreatic β-cells. PMID:30927092
Tutorial on lipidomics. PMID:30926037
Mitochondria in precision medicine; linking bioenergetics and metabolomics in platelets. PMID:30877854
Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer. PMID:30846479
Metabolomic Insights into Human Arboviral Infections: Dengue, Chikungunya, and Zika Viruses. PMID:30845653
RANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies. PMID:30830432
Review of recent developments in GC-MS approaches to metabolomics-based research. PMID:30830421
Volatile metabolomic signature of bladder cancer cell lines based on gas chromatography-mass spectrometry. PMID:30830384
Characterization of trotter horses urine metabolome by means of proton nuclear magnetic resonance spectroscopy. PMID:30830366
Metabolomic prediction of endometrial cancer. PMID:30830361
Organic washes of tissue sections for comprehensive analysis of small molecule metabolites by MALDI MS imaging of rat brain following status epilepticus. PMID:30830331
Untargeted metabolomics by high resolution mass spectrometry coupled to normal and reversed phase liquid chromatography as a tool to study the in vitro biotransformation of new psychoactive substances. PMID:30808896
Quality Control of Therapeutic Peptides by 1H NMR HiFSA Sequencing. PMID:30793905
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0. PMID:30787451
Metabolomics Approaches for the Diagnosis and Understanding of Kidney Diseases. PMID:30769897
Consistency, Inconsistency, and Ambiguity of Metabolite Names in Biochemical Databases Used for Genome-Scale Metabolic Modelling. PMID:30736318
Identification of Pre-frailty Sub-Phenotypes in Elderly Using Metabolomics. PMID:30733683
GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells. PMID:30669322
Metabolic perturbations in classic galactosemia beyond the Leloir pathway: Insights from an untargeted metabolomic study. PMID:30667068
Dimethyl fumarate treatment induces lipid metabolism alterations that are linked to immunological changes. PMID:30656182
Leveraging Multilayered "Omics" Data for Atopic Dermatitis: A Road Map to Precision Medicine. PMID:30631320
Peak Annotation and Verification Engine for Untargeted LC-MS Metabolomics. PMID:30586294
Study of Methanol Extracts from Different Parts of Peganum harmala L. Using 1H-NMR Plant Metabolomics. PMID:30581649
A robust intracellular metabolite extraction protocol for human neutrophil metabolic profiling. PMID:30571714
Gut microbiome structure and metabolic activity in inflammatory bowel disease. PMID:30531976
Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung. PMID:30529385
New Pim-1 Kinase Inhibitor From the Co-culture of Two Sponge-Associated Actinomycetes. PMID:30525020
Metabolic control of PPAR activity by aldehyde dehydrogenase regulates invasive cell behavior and predicts survival in hepatocellular and renal clear cell carcinoma. PMID:30486822
The influence of surface chemistry on the kinetics and thermodynamics of bacterial adhesion. PMID:30467352
Effect of dietary arginine to lysine ratios on productive performance, meat quality, plasma and muscle metabolomics profile in fast-growing broiler chickens. PMID:30455879
Impact of meropenem on Klebsiella pneumoniae metabolism. PMID:30440048
A Mobile-Based Diet Monitoring System for Obesity Management. PMID:30416865
Determinants of the urinary and serum metabolome in children from six European populations. PMID:30404627
Diapause-associated changes in the lipid and metabolite profiles of the Asian tiger mosquito, Aedes albopictus. PMID:30385483
The proteomic and metabolomic characterization of exercise-induced sweat for human performance monitoring: A pilot investigation. PMID:30383773
Evaluation of sample preparation methods for NMR-based metabolomics of cow milk. PMID:30364606
Fingerprinting Acute Digestive Diseases by Untargeted NMR Based Metabolomics. PMID:30360494
Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells. PMID:30349315
Effects of Unfiltered Coffee and Bioactive Coffee Compounds on the Development of Metabolic Syndrome Components in a High-Fat-/High-Fructose-Fed Rat Model. PMID:30347674
Untargeted lipidomic features associated with colorectal cancer in a prospective cohort. PMID:30340609
Investigating the aetiology of adverse events following HPV vaccination with systems vaccinology. PMID:30324425
Hydroxyurea Treated β-Thalassemia Children Demonstrate a Shift in Metabolism Towards Healthy Pattern. PMID:30310134
High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans. PMID:30308073
Metabolomics: a challenge for detecting and monitoring inborn errors of metabolism. PMID:30306077
Deep analysis of immune response and metabolic signature in children with food protein induced enterocolitis to cow's milk. PMID:30275944
Nuclear Magnetic Resonance technique in tumor metabolism. PMID:30258906
Metabolomics Approach for Validation of Self-Reported Ibuprofen and Acetaminophen Use. PMID:30248901
Sarcolab pilot study into skeletal muscle's adaptation to long-term spaceflight. PMID:30246141
Mind the Gap: Mapping Mass Spectral Databases in Genome-Scale Metabolic Networks Reveals Poorly Covered Areas. PMID:30223552
Network analysis of membranous glomerulonephritis based on metabolomics data. PMID:30221719
Integration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis. PMID:30214633
900MHz 1H-/13C-NMR analysis of 2-hydroxyglutarate and other brain metabolites in human brain tumor tissue extracts. PMID:30192797
Hematological, Biochemical, Histopathological and ¹H-NMR Metabolomics Application in Acute Toxicity Evaluation of Clinacanthus nutans Water Leaf Extract. PMID:30158427
The Omics Revolution Continues: The Maturation of High-Throughput Biological Data Sources. PMID:30157526
Prenatal Maternal Stress from a Natural Disaster Alters Urinary Metabolomic Profiles in Project Ice Storm Participants. PMID:30154530
Applications of Parametrized NMR Spin Systems of Small Molecules. PMID:30125102
Therapeutic reduction of lysophospholipids in the digestive tract recapitulates the metabolic benefits of bariatric surgery and promotes diabetes remission. PMID:30087032
Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis. PMID:30075744
Epigenetic Modifiers Induce Bioactive Phenolic Metabolites in the Marine-Derived Fungus Penicillium brevicompactum. PMID:30061488
MoDentify: phenotype-driven module identification in metabolomics networks at different resolutions. PMID:30032270
NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer. PMID:30016349
High-Throughput Metabolomics by 1D NMR. PMID:29999221
Effect of Tumor Relevant Acidic Environment in the Interaction of a N-hydroxyindole-2-Carboxylic Derivative with the Phospholipid Bilayer. PMID:29987655
The assessment of metabolite alteration induced by -OH functionalized multi-walled carbon nanotubes in mice using NMR-based metabonomics. PMID:29977832
Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry. PMID:29949055
Systems-Based Interactome Analysis for Hematopoiesis Effect of Angelicae sinensis Radix: Regulated Network of Cell Proliferation towards Hemopoiesis. PMID:29943236
Robust imaging and gene delivery to study human lymphoblastoid cell lines. PMID:29925960
Physicochemical Prediction of Metabolite Fragmentation in Tandem Mass Spectrometry. PMID:29922568
Novel Metabolomic Comparison of Arterial and Jugular Venous Blood in Severe Adult Traumatic Brain Injury Patients and the Impact of Pentobarbital Infusion. PMID:29901425
A systematic approach to identify therapeutic effects of natural products based on human metabolite information. PMID:29897322
A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor. PMID:29892571
Tocotrienol-Rich Fraction of Palm Oil Improves Behavioral Impairments and Regulates Metabolic Pathways in AβPP/PS1 Mice. PMID:29889072
Network-based machine learning and graph theory algorithms for precision oncology. PMID:29872707
Reverse Screening Methods to Search for the Protein Targets of Chemopreventive Compounds. PMID:29868550
Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion. PMID:29867102
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome. PMID:29851973
In-Vivo NMR Spectroscopy: A Powerful and Complimentary Tool for Understanding Environmental Toxicity. PMID:29795000
Metabolomic profile of systemic sclerosis patients. PMID:29769578
Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. PMID:29742587
Metabolomics and Isotope Tracing. PMID:29727671
Integration of genomics and metabolomics for prioritization of rare disease variants: a 2018 literature review. PMID:29721916
Cardiovascular Metabolomics. PMID:29700070
Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages. PMID:29694888
Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation. PMID:29692630
OliveNet™: a comprehensive library of compounds from Olea europaea. PMID:29688352
DuCLOX-2/5 Inhibition Attenuates Inflammatory Response and Induces Mitochondrial Apoptosis for Mammary Gland Chemoprevention. PMID:29681851
Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent. PMID:29679745
A probiotic modulates the microbiome and immunity in multiple sclerosis. PMID:29679417
A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence. PMID:29679203
Probiotic supplementation in trained trotter horses: effect on blood clinical pathology data and urine metabolomic assessed in field. PMID:29672225
The role of the Human Metabolome Database in inborn errors of metabolism. PMID:29663269
High-content screen for modifiers of Niemann-Pick type C disease in patient cells. PMID:29659804
Deep learning meets ontologies: experiments to anchor the cardiovascular disease ontology in the biomedical literature. PMID:29650041
LipidPedia: a comprehensive lipid knowledgebase. PMID:29648583
Metabolomics: Eavesdropping on silent conversations between hosts and their unwelcome guests. PMID:29621358
Metabolomics activity screening for identifying metabolites that modulate phenotype. PMID:29621222
Toxigenic effects of two benthic diatoms upon grazing activity of the sea urchin: morphological, metabolomic and de novo transcriptomic analysis. PMID:29618786
Discrimination between the human prostate normal and cancer cell exometabolome by GC-MS. PMID:29615722
Bayesian estimation of the number of protonation sites for urinary metabolites from NMR spectroscopic data. PMID:29606928
Route of Glucose Uptake in the Group a Streptococcus Impacts SLS-Mediated Hemolysis and Survival in Human Blood. PMID:29594067
Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer. PMID:29582397
Profiling of small molecule metabolites and neurotransmitters in crustacean hemolymph and neuronal tissues using reversed-phase LC-MS/MS. PMID:29579349
Metabolic perturbations in Welsh Ponies with insulin dysregulation, obesity, and laminitis. PMID:29572947
A structural examination and collision cross section database for over 500 metabolites and xenobiotics using drift tube ion mobility spectrometry. PMID:29568436
Non-Uniform and Absolute Minimal Sampling for High-Throughput Multidimensional NMR Applications. PMID:29566285
Urine metabolome in women with Chlamydia trachomatis infection. PMID:29566085
GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells. PMID:29562689
Anthocyanin-Rich Grape Pomace Extract (Vitis vinifera L.) from Wine Industry Affects Mitochondrial Bioenergetics and Glucose Metabolism in Human Hepatocarcinoma HepG2 Cells. PMID:29518033
Integrating Proteomics and Targeted Metabolomics to Understand Global Changes in Histone Modifications. PMID:29512899
IntLIM: integration using linear models of metabolomics and gene expression data. PMID:29506475
speaq 2.0: A complete workflow for high-throughput 1D NMR spectra processing and quantification. PMID:29494588
Development of a Reverse Phase HPLC Retention Index Model for Nontargeted Metabolomics Using Synthetic Compounds. PMID:29489351
Guidelines for Biomarker of Food Intake Reviews (BFIRev): how to conduct an extensive literature search for biomarker of food intake discovery. PMID:29484030
Deletion of the neural tube defect-associated gene Mthfd1l disrupts one-carbon and central energy metabolism in mouse embryos. PMID:29483189
Borrelia burgdorferi genes, bb0639-0642, encode a putative putrescine/spermidine transport system, PotABCD, that is spermidine specific and essential for cell survival. PMID:29476656
RaMP: A Comprehensive Relational Database of Metabolomics Pathways for Pathway Enrichment Analysis of Genes and Metabolites. PMID:29470400
Next-generation metabolic screening: targeted and untargeted metabolomics for the diagnosis of inborn errors of metabolism in individual patients. PMID:29453510
Effectiveness and Safety of a Probiotic-Mixture for the Treatment of Infantile Colic: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial with Fecal Real-Time PCR and NMR-Based Metabolomics Analysis. PMID:29439395
Hypoxia-activated evofosfamide for treatment of recurrent bevacizumab-refractory glioblastoma: a phase I surgical study. PMID:29415215
A Landscape of Metabolic Variation across Tumor Types. PMID:29396322
Comparative analysis of cerebrospinal fluid metabolites in Alzheimer's disease and idiopathic normal pressure hydrocephalus in a Japanese cohort. PMID:29387418
High-Resolution Tissue Mass Spectrometry Imaging Reveals a Refined Functional Anatomy of the Human Adult Adrenal Gland. PMID:29385420
METLIN: A Technology Platform for Identifying Knowns and Unknowns. PMID:29381867
Beyond genomics: understanding exposotypes through metabolomics. PMID:29373992
High-throughput screen for compounds that modulate neurite growth of human induced pluripotent stem cell-derived neurons. PMID:29361516
Challenges in integrating component level technology and system level information from Ayurveda: Insights from NMR phytometabolomics and anti-HIV potential of select Ayurvedic medicinal plants. PMID:29306573
Metabolomics technology and bioinformatics for precision medicine. PMID:29304189
Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches. PMID:29299119
Unique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis. PMID:29291380
SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids. PMID:29276770
Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B. PMID:29262552
Untargeted serum metabonomics study of psoriasis vulgaris based on ultra-performance liquid chromatography coupled to mass spectrometry. PMID:29221177
Meta-Analysis of Fecal Microbiota and Metabolites in Experimental Colitic Mice during the Inflammatory and Healing Phases. PMID:29211010
Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease. PMID:29208041
Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism. PMID:29202102
The Scope of Big Data in One Medicine: Unprecedented Opportunities and Challenges. PMID:29201868
Spectropathology-corroborated multimodal quantitative imaging biomarkers for neuroretinal degeneration in diabetic retinopathy. PMID:29200821
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry. PMID:29185060
Blood serum metabolome of atopic dermatitis: Altered energy cycle and the markers of systemic inflammation. PMID:29176763
Integrated Proteomic and Metabolomic prediction of Term Preeclampsia. PMID:29170520
Efficacy and Safety of a Multistrain Probiotic Formulation Depends from Manufacturing. PMID:29163538
NMR-Based Identification of Metabolites in Polar and Non-Polar Extracts of Avian Liver. PMID:29144418
HMDB 4.0: the human metabolome database for 2018. PMID:29140435
PAMDB: a comprehensive Pseudomonas aeruginosa metabolome database. PMID:29106626
Comparative evaluation of atom mapping algorithms for balanced metabolic reactions: application to Recon 3D. PMID:29086112
Spin System Modeling of Nuclear Magnetic Resonance Spectra for Applications in Metabolomics and Small Molecule Screening. PMID:29058410
Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention. PMID:29050261
Lipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis. PMID:29046044
Impact of Dietary Resistant Starch on the Human Gut Microbiome, Metaproteome, and Metabolome. PMID:29042495
Ion Mobility Spectrometry-Mass Spectrometry Coupled with Gas-Phase Hydrogen/Deuterium Exchange for Metabolomics Analyses. PMID:28956290
Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig. PMID:28955207
Similarity of High-Resolution Tandem Mass Spectrometry Spectra of Structurally Related Micropollutants and Transformation Products. PMID:28952028
Phenotype-driven identification of modules in a hierarchical map of multifluid metabolic correlations. PMID:28948040
Short overview on metabolomic approach and redox changes in psychiatric disorders. PMID:28942195
Metabolomics of Diabetic Retinopathy. PMID:28940103
Pharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD. PMID:28924233
Profiling novel metabolic biomarkers for Parkinson's disease using in-depth metabolomic analysis. PMID:28880465
Using Accurate Mass Gas Chromatography-Mass Spectrometry with the MINE Database for Epimetabolite Annotation. PMID:28876899
Short overview on metabolomics approach to study pathophysiology of oxidative stress in cancer. PMID:28866248
Evidence for Altered Glutamine Metabolism in Human Immunodeficiency Virus Type 1 Infected Primary Human CD4+ T Cells. PMID:28844150
Cross sectional evaluation of the gut-microbiome metabolome axis in an Italian cohort of IBD patients. PMID:28842640
Improving Visualization and Interpretation of Metabolome-Wide Association Studies: An Application in a Population-Based Cohort Using Untargeted 1H NMR Metabolic Profiling. PMID:28823158
Biomarker Research in Parkinson's Disease Using Metabolite Profiling. PMID:28800113
Working Up a Good Sweat - The Challenges of Standardising Sweat Collection for Metabolomics Analysis. PMID:28798503
Metabolomic Evaluation of the Consequences of Plasma Cystathionine Elevation in Adults with Stable Angina Pectoris. PMID:28794210
Ambient mass spectrometry in metabolomics. PMID:28792022
Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease. PMID:28785375
Genome-Scale Modeling of NADPH-Driven β-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma. PMID:28762750
Low-level maternal exposure to nicotine associates with significant metabolic perturbations in second-trimester amniotic fluid. PMID:28759762
PCSF: An R-package for network-based interpretation of high-throughput data. PMID:28759592
Microscale Mass Spectrometry Analysis of Extracellular Metabolites in Live Multicellular Tumor Spheroids. PMID:28753268
Nuclear Magnetic Resonance-Based Metabolomics Approach to Evaluate the Prevention Effect of Camellia nitidissima Chi on Colitis-Associated Carcinogenesis. PMID:28744216
Gut microbiota and IBD: causation or correlation? PMID:28743984
NMR analysis reveals significant differences in the plasma metabolic profiles of Niemann Pick C1 patients, heterozygous carriers, and healthy controls. PMID:28740230
Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance. PMID:28724354
Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment. PMID:28706260
The metabolic analysis of psoriasis identifies the associated metabolites while providing computational models for the monitoring of the disease. PMID:28695330
Application of metabolomics in sarcoma: From biomarkers to therapeutic targets. PMID:28693790
The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization. PMID:28691704
Metabolomic Studies in Drosophila. PMID:28684601
The Plasma and Serum Metabotyping of Hepatocellular Carcinoma in a Nigerian and Egyptian Cohort using Proton Nuclear Magnetic Resonance Spectroscopy. PMID:28663670
Metabolite profiling in identifying metabolic biomarkers in older people with late-onset type 2 diabetes mellitus. PMID:28663594
A Robust Lipidomics Workflow for Mammalian Cells, Plasma, and Tissue Using Liquid-Chromatography High-Resolution Tandem Mass Spectrometry. PMID:28660577
Development and Validation of a High-Throughput Mass Spectrometry Based Urine Metabolomic Test for the Detection of Colonic Adenomatous Polyps. PMID:28640228
Biofluid lipidome: a source for potential diagnostic biomarkers. PMID:28639235
Metabolomics as a Driver in Advancing Precision Medicine in Sepsis. PMID:28632924
The early metabolomic response of adipose tissue during acute cold exposure in mice. PMID:28615704
Maximal clique method for the automated analysis of NMR TOCSY spectra of complex mixtures. PMID:28573376
Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis. PMID:28558019
Human plasma metabolomics in age-related macular degeneration (AMD) using nuclear magnetic resonance spectroscopy. PMID:28542375
Unique identifiers for small molecules enable rigorous labeling of their atoms. PMID:28534867
Livestock metabolomics and the livestock metabolome: A systematic review. PMID:28531195
Application of metabolomics: Focus on the quantification of organic acids in healthy adults. PMID:28498405
A review of metabolomics approaches and their application in identifying causal pathways of childhood asthma. PMID:28479327
Simultaneous Quantification of Amino Metabolites in Multiple Metabolic Pathways Using Ultra-High Performance Liquid Chromatography with Tandem-mass Spectrometry. PMID:28469184
1H-NMR, 1H-NMR T2-edited, and 2D-NMR in bipolar disorder metabolic profiling. PMID:28447334
Cytoskeletal stability and metabolic alterations in primary human macrophages in long-term microgravity. PMID:28419128
Three serum metabolite signatures for diagnosing low-grade and high-grade bladder cancer. PMID:28382976
Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample. PMID:28378853
Bioavailability of Microencapsulated Iron from Fortified Bread Assessed Using Piglet Model. PMID:28335378
Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library. PMID:28316657
Expanding the phenotype in argininosuccinic aciduria: need for new therapies. PMID:28251416
The Importance of Endophenotypes to Evaluate the Relationship between Genotype and External Phenotype. PMID:28241430
The human brain produces fructose from glucose. PMID:28239653
compMS2Miner: An Automatable Metabolite Identification, Visualization, and Data-Sharing R Package for High-Resolution LC-MS Data Sets. PMID:28225587
1H NMR spectra dataset and solid-state NMR data of cowpea (Vigna unguiculata). PMID:28224130
β-Thalassemia Patients Revealed a Significant Change of Untargeted Metabolites in Comparison to Healthy Individuals. PMID:28198811
NMR metabolic fingerprints of murine melanocyte and melanoma cell lines: application to biomarker discovery. PMID:28198377
Genetic and biochemical changes of the serotonergic system in migraine pathobiology. PMID:28194570
A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations. PMID:28151932
How close are we to complete annotation of metabolomes? PMID:28113135
Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. PMID:28112165
Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole‑time‑of‑flight mass spectrometry. PMID:28098892
Global open data management in metabolomics. PMID:28092796
13C Metabolomics: NMR and IROA for Unknown Identification. PMID:28090435
Metabotyping Patients' Journeys Reveals Early Predisposition to Lung Injury after Cardiac Surgery. PMID:28074924
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection. PMID:28069010
Metabolomic Approaches to Explore Chemical Diversity of Human Breast-Milk, Formula Milk and Bovine Milk. PMID:27999311
Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases. PMID:27941699
Technical Challenges in Mass Spectrometry-Based Metabolomics. PMID:27900235
Whole-genome metabolic model of Trichoderma reesei built by comparative reconstruction. PMID:27895706
Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease. PMID:27889911
Spectroscopic and E-tongue evaluation of medicinal plants: A taste of how rasa can be studied. PMID:27889428
Electrospray deposition device used to precisely control the matrix crystal to improve the performance of MALDI MSI. PMID:27885266
Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. PMID:27869804
Lifestyle chemistries from phones for individual profiling. PMID:27849584
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. PMID:27832762
Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. PMID:27789671
Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models. PMID:27784287
Noninvasive Recognition and Biomarkers of Early Allergic Asthma in Cats Using Multivariate Statistical Analysis of NMR Spectra of Exhaled Breath Condensate. PMID:27764146
Urinary Metabotyping of Hepatocellular Carcinoma in a UK Cohort Using Proton Nuclear Magnetic Resonance Spectroscopy. PMID:27746614
A high-fat high-sucrose diet affects the long-term metabolic fate of grape proanthocyanidins in rats. PMID:27730364
Metabolite and Microbiome Interplay in Cancer Immunotherapy. PMID:27729325
Untargeted NMR Spectroscopic Analysis of the Metabolic Variety of New Apple Cultivars. PMID:27657148
Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis. PMID:27651926
Theoretical investigation of loratadine reactivity in order to understand its degradation properties: DFT and MD study. PMID:27640160
Cellular Metabolomics Revealed the Cytoprotection of Amentoflavone, a Natural Compound, in Lipopolysaccharide-Induced Injury of Human Umbilical Vein Endothelial Cells. PMID:27618027
Metabolomic profiling of brain from infants who died from Sudden Infant Death Syndrome reveals novel predictive biomarkers. PMID:27608295
Post-acquisition filtering of salt cluster artefacts for LC-MS based human metabolomic studies. PMID:27606010
An Untargeted Metabolomics Approach to Characterize Short-Term and Long-Term Metabolic Changes after Bariatric Surgery. PMID:27584017
Plasma Biomarkers for Monitoring Brain Pathophysiology in FMR1 Premutation Carriers. PMID:27570505
A validated metabolomic signature for colorectal cancer: exploration of the clinical value of metabolomics. PMID:27560555
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer. PMID:27559084
Plasma metabolic profile delineates roles for neurodegeneration, pro-inflammatory damage and mitochondrial dysfunction in the FMR1 premutation. PMID:27555610
Colonic Transit Time Is a Driven Force of the Gut Microbiota Composition and Metabolism: In Vitro Evidence. PMID:27530163
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. PMID:27504778
(13)C glucose labelling studies using 2D NMR are a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys. PMID:27499851
Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics. PMID:27471436
Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function. PMID:27456714
Preterm neonatal urinary renal developmental and acute kidney injury metabolomic profiling: an exploratory study. PMID:27435284
Hydrogen Rearrangement Rules: Computational MS/MS Fragmentation and Structure Elucidation Using MS-FINDER Software. PMID:27419259
Pro-Oxidant Role of Silibinin in DMBA/TPA Induced Skin Cancer: 1H NMR Metabolomic and Biochemical Study. PMID:27414401
BcCluster: A Bladder Cancer Database at the Molecular Level. PMID:27376128
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins. PMID:27374120
NMR-based metabolomics reveals urinary metabolome modifications in female Sprague-Dawley rats by cranberry procyanidins. PMID:27309592
Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge. PMID:27306312
The Importance of the Biological Impact of Exposure to the Concept of the Exposome. PMID:27258438
Development of Database Assisted Structure Identification (DASI) Methods for Nontargeted Metabolomics. PMID:27258318
Protein Disulfide Levels and Lens Elasticity Modulation: Applications for Presbyopia. PMID:27233034
Feasibility Study of NMR Based Serum Metabolomic Profiling to Animal Health Monitoring: A Case Study on Iron Storage Disease in Captive Sumatran Rhinoceros (Dicerorhinus sumatrensis). PMID:27232336
Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics. PMID:27231903
Reactome from a WikiPathways Perspective. PMID:27203685
LacaScore: a novel plasma sample quality control tool based on ascorbic acid and lactic acid levels. PMID:27199628
Metagenomics, Metatranscriptomics, and Metabolomics Approaches for Microbiome Analysis. PMID:27199545
Stress transgenerationally programs metabolic pathways linked to altered mental health. PMID:27188285
In vivo gene expression in a Staphylococcus aureus prosthetic joint infection characterized by RNA sequencing and metabolomics: a pilot study. PMID:27150914
Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain. PMID:27142336
Urinary nuclear magnetic resonance spectroscopy of a Bangladeshi cohort with hepatitis-B hepatocellular carcinoma: A biomarker corroboration study. PMID:27122669
GAM: a web-service for integrated transcriptional and metabolic network analysis. PMID:27098040
Pharmacometabolomics-aided Pharmacogenomics in Autoimmune Disease. PMID:27077110
Hepatocellular carcinoma: Review of disease and tumor biomarkers. PMID:27057305
Metabolomic network analysis of estrogen-stimulated MCF-7 cells: a comparison of overrepresentation analysis, quantitative enrichment analysis and pathway analysis versus metabolite network analysis. PMID:27039105
HNdb: an integrated database of gene and protein information on head and neck squamous cell carcinoma. PMID:27013077
Dietary intake of heat-killed Lactococcus lactis H61 delays age-related hearing loss in C57BL/6J mice. PMID:27000949
Metabolomics: beyond biomarkers and towards mechanisms. PMID:26979502
Cancer Metabolomics and the Human Metabolome Database. PMID:26950159
Metabolic profiling during ex vivo machine perfusion of the human liver. PMID:26935866
Integrated metabolomics and metagenomics analysis of plasma and urine identified microbial metabolites associated with coronary heart disease. PMID:26932197
Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication. PMID:26923630
Metabolomics-Based Discovery of Small Molecule Biomarkers in Serum Associated with Dengue Virus Infections and Disease Outcomes. PMID:26913918
Magnetic Resonance Spectroscopy: Principles and Techniques: Lessons for Clinicians. PMID:26900274
Plasma Lipid Profiling in a Rat Model of Hepatocellular Carcinoma: Potential Modulation Through Quinolone Administration. PMID:26900269
1001 Ways to run AutoDock Vina for virtual screening. PMID:26897747
Systems Biology Approaches for Host-Fungal Interactions: An Expanding Multi-Omics Frontier. PMID:26885725
Using "Omics" and Integrated Multi-Omics Approaches to Guide Probiotic Selection to Mitigate Chytridiomycosis and Other Emerging Infectious Diseases. PMID:26870025
TD-GC-MS Investigation of the VOCs Released from Blood Plasma of Dogs with Cancer. PMID:26835668
Rethinking Mass Spectrometry-Based Small Molecule Identification Strategies in Metabolomics. PMID:26819881
Nuclear magnetic resonance based metabolomics and liver diseases: Recent advances and future clinical applications. PMID:26755887
Blood transcriptomics and metabolomics for personalized medicine. PMID:26702339
High-Throughput Metabolic Profiling of Soybean Leaves by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. PMID:26651857
Challenges of liver cancer: Future emerging tools in imaging and urinary biomarkers. PMID:26609343
Ayurnutrigenomics: Ayurveda-inspired personalized nutrition from inception to evidence. PMID:26587393
Ambiguity of non-systematic chemical identifiers within and between small-molecule databases. PMID:26579214
Strategy and rationale for urine collection protocols employed in the NEPTUNE study. PMID:26577187
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism. PMID:26522426
Identification of Chemical Toxicity Using Ontology Information of Chemicals. PMID:26508991
NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass. PMID:26479316
Physicochemical characteristics of structurally determined metabolite-protein and drug-protein binding events with respect to binding specificity. PMID:26442281
The Intervention Effects of Acupuncture on Fatigue Induced by Exhaustive Physical Exercises: A Metabolomics Investigation. PMID:26442121
Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected by Anaplasma phagocytophilum Infection in Tick Cells. PMID:26424601
Application of NMR-based metabolomics for environmental assessment in the Great Lakes using zebra mussel (Dreissena polymorpha). PMID:26366138
Impact of collection conditions on the metabolite content of human urine samples as analyzed by liquid chromatography coupled to mass spectrometry and nuclear magnetic resonance spectroscopy. PMID:26366133
Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease. PMID:26342919
Profiling the metabolome changes caused by cranberry procyanidins in plasma of female rats using (1) H NMR and UHPLC-Q-Orbitrap-HRMS global metabolomics approaches. PMID:26264887
NMR-Based Metabolic Profiling Reveals Neurochemical Alterations in the Brain of Rats Treated with Sorafenib. PMID:26233726
Analytical strategies for studying stem cell metabolism. PMID:26213533
Human metabolic atlas: an online resource for human metabolism. PMID:26209309
High-Resolution Metabolomics: Review of the Field and Implications for Nursing Science and the Study of Preterm Birth. PMID:26183181
NMR-Based Metabolomics Separates the Distinct Stages of Disease in a Chronic Relapsing Model of Multiple Sclerosis. PMID:26155956
1H nuclear magnetic resonance-based extracellular metabolomic analysis of multidrug resistant Tca8113 oral squamous carcinoma cells. PMID:26137105
Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review. PMID:26109927
The ACTN3 R577X Polymorphism Is Associated with Cardiometabolic Fitness in Healthy Young Adults. PMID:26107372
Applying (1)H NMR Spectroscopy to Detect Changes in the Urinary Metabolite Levels of Chinese Half-Pipe Snowboarders after Different Exercises. PMID:26101694
Many InChIs and quite some feat. PMID:26081259
Multivariate Analysis in Metabolomics. PMID:26078916
Mass Spectrometry-based Lipidomics and Its Application to Biomedical Research. PMID:26064851
Accurate, fully-automated NMR spectral profiling for metabolomics. PMID:26017271
A metabolomic approach to dry eye disorders. The role of oral supplements with antioxidants and omega 3 fatty acids. PMID:25999682
Reverse enGENEering of Regulatory Networks from Big Data: A Roadmap for Biologists. PMID:25983554
Application of metabolomics in thyroid cancer research. PMID:25972898
Mitochondrial responses to extreme environments: insights from metabolomics. PMID:25949809
Predicting drug metabolism: experiment and/or computation? PMID:25907346
Module-based association analysis for omics data with network structure. PMID:25822417
Recognition of chemical entities: combining dictionary-based and grammar-based approaches. PMID:25810767
Combining DI-ESI-MS and NMR datasets for metabolic profiling. PMID:25774104
The protein kinase promiscuities in the cancer-preventive mechanisms of NSAIDs. PMID:25714784
Selective paired ion contrast analysis: a novel algorithm for analyzing postprocessed LC-MS metabolomics data possessing high experimental noise. PMID:25683158
Next-generation technologies for multiomics approaches including interactome sequencing. PMID:25649523
Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations. PMID:25645828
Dosage Effects of Salt and pH Stresses on Saccharomyces cerevisiae as Monitored via Metabolites by Using Two Dimensional NMR Spectroscopy. PMID:25642011
Metabolome profiling by HRMAS NMR spectroscopy of pheochromocytomas and paragangliomas detects SDH deficiency: clinical and pathophysiological implications. PMID:25622899
Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients. PMID:25611149
Workflows for automated downstream data analysis and visualization in large-scale computational mass spectrometry. PMID:25604327
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. PMID:25599126
An In Silico Approach towards the Prediction of Druglikeness Properties of Inhibitors of Plasminogen Activator Inhibitor1. PMID:25580120
Genome-scale modeling for metabolic engineering. PMID:25578304
Protein interactome of muscle invasive bladder cancer. PMID:25569276
MetaDB a Data Processing Workflow in Untargeted MS-Based Metabolomics Experiments. PMID:25566535
NMR spectroscopic search module for Spektraris, an online resource for plant natural product identification--Taxane diterpenoids from Taxus × media cell suspension cultures as a case study. PMID:25534952
Subcellular metabolite and lipid analysis of Xenopus laevis eggs by LAESI mass spectrometry. PMID:25506922
Dose-dependent metabolic alterations in human cells exposed to gamma irradiation. PMID:25419661
Global metabolomic and isobaric tagging capillary liquid chromatography-tandem mass spectrometry approaches for uncovering pathway dysfunction in diabetic mouse aorta. PMID:25368974
Folic acid induces salicylic acid-dependent immunity in Arabidopsis and enhances susceptibility to Alternaria brassicicola. PMID:25348251
Glycolysis and the pentose phosphate pathway after human traumatic brain injury: microdialysis studies using 1,2-(13)C2 glucose. PMID:25335801
The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. PMID:25299963
Choline kinase inhibition in rheumatoid arthritis. PMID:25274633
Unraveling biochemical pathways affected by mitochondrial dysfunctions using metabolomic approaches. PMID:25257998
A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis. PMID:25253748
The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity. PMID:25244648
Metabolomic analysis of akt1-mediated muscle hypertrophy in models of diet-induced obesity and age-related fat accumulation. PMID:25231380
TMDB: a literature-curated database for small molecular compounds found from tea. PMID:25224438
Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. PMID:25220639
Diagnosing impaired glucose tolerance using direct infusion mass spectrometry of blood plasma. PMID:25202985
Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 promotes systemic acquired resistance via azelaic acid and its precursor 9-oxo nonanoic acid. PMID:25114016
MPINet: metabolite pathway identification via coupling of global metabolite network structure and metabolomic profile. PMID:25057481
Emerging biomarkers and metabolomics for assessing toxic nephropathy and acute kidney injury (AKI) in neonatology. PMID:25013791
A computational approach to estimate interorgan metabolic transport in a mammal. PMID:24971892
Differential effects of dry eye disorders on metabolomic profile by 1H nuclear magnetic resonance spectroscopy. PMID:24967377
Tackling CASMI 2012: Solutions from MetFrag and MetFusion. PMID:24958142
A review of applications of metabolomics in cancer. PMID:24958139
The Effect of LC-MS Data Preprocessing Methods on the Selection of Plasma Biomarkers in Fed vs. Fasted Rats. PMID:24957369
MALDI Mass Spectrometry Imaging for Visualizing In Situ Metabolism of Endogenous Metabolites and Dietary Phytochemicals. PMID:24957029
Nanoinformatics knowledge infrastructures: bringing efficient information management to nanomedical research. PMID:24932210
Metabolomics and proteomics reveal impacts of chemically mediated competition on marine plankton. PMID:24889616
Challenges in accurate quantitation of lysophosphatidic acids in human biofluids. PMID:24872406
Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. PMID:24856386
Bayesian deconvolution and quantification of metabolites in complex 1D NMR spectra using BATMAN. PMID:24853927
Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by (1)H-NMR Metabolic Profiling. PMID:24826194
Integrating omics technologies to study pulmonary physiology and pathology at the systems level. PMID:24802001
Metabolomics in nutritional epidemiology: identifying metabolites associated with diet and quantifying their potential to uncover diet-disease relations in populations. PMID:24740205
Urinary loss of tricarboxylic acid cycle intermediates as revealed by metabolomics studies: an underlying mechanism to reduce lipid accretion by whey protein ingestion? PMID:24702026
Metabolomics network characterization of resuscitation after normocapnic hypoxia in a newborn piglet model supports the hypothesis that room air is better. PMID:24696864
Chemical structure identification in metabolomics: computational modeling of experimental features. PMID:24688698
Integrated LC-MS/MS system for plant metabolomics. PMID:24688692
Computational tools for the secondary analysis of metabolomics experiments. PMID:24688685
A metabolomic perspective on coeliac disease. PMID:24665364
Metabonomic analysis of water extracts from different angelica roots by ¹H-nuclear magnetic resonance spectroscopy. PMID:24658570
Whole blood transcriptomics and urinary metabolomics to define adaptive biochemical pathways of high-intensity exercise in 50-60 year old masters athletes. PMID:24643011
Cordyceps sinensis protects against liver and heart injuries in a rat model of chronic kidney disease: a metabolomic analysis. PMID:24632844
Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma. PMID:24603425
Metabotyping of docosahexaenoic acid - treated Alzheimer's disease cell model. PMID:24587236
Metabolomic fingerprinting: challenges and opportunities. PMID:24579644
1H-Nuclear magnetic resonance-based metabolomic analysis of brain in mice with nicotine treatment. PMID:24558969
Metabolomic insights into system-wide coordination of vertebrate metamorphosis. PMID:24495308
Mechanisms of metabonomic for a gateway drug: nicotine priming enhances behavioral response to cocaine with modification in energy metabolism and neurotransmitter level. PMID:24489831
Mealtime, temporal, and daily variability of the human urinary and plasma metabolomes in a tightly controlled environment. PMID:24475090
Comparative evaluation of open source software for mapping between metabolite identifiers in metabolic network reconstructions: application to Recon 2. PMID:24468196
Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism. PMID:24391526
A new specific succinate-glutamate metabolomic hallmark in SDHx-related paragangliomas. PMID:24312232
Controllability in cancer metabolic networks according to drug targets as driver nodes. PMID:24282504
MetaboLyzer: a novel statistical workflow for analyzing Postprocessed LC-MS metabolomics data. PMID:24266674
Databases and Software for NMR-Based Metabolomics. PMID:24260723
Development of a Standard Reference Material for metabolomics research. PMID:24187941
Automated label-free quantification of metabolites from liquid chromatography-mass spectrometry data. PMID:24176773
In situ label-free imaging for visualizing the biotransformation of a bioactive polyphenol. PMID:24076623
Doping control using high and ultra-high resolution mass spectrometry based non-targeted metabolomics-a case study of salbutamol and budesonide abuse. PMID:24058591
Postgenomics diagnostics: metabolomics approaches to human blood profiling. PMID:24044364
High-fat diet alters gut microbiota physiology in mice. PMID:24030595
Proton fingerprints portray molecular structures: enhanced description of the 1H NMR spectra of small molecules. PMID:24007197
In silico enzymatic synthesis of a 400,000 compound biochemical database for nontargeted metabolomics. PMID:23991755
Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer. PMID:23943330
An analysis of a 'community-driven' reconstruction of the human metabolic network. PMID:23888127
Methodological approaches to help unravel the intracellular metabolome of Bacillus subtilis. PMID:23844891
The impact of inflammation on metabolomic profiles in patients with arthritis. PMID:23740368
Review: toxicometabolomics. PMID:23722930
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia. PMID:23643539
The MetaboLights repository: curation challenges in metabolomics. PMID:23630246
NGAL and metabolomics: the single biomarker to reveal the metabolome alterations in kidney injury. PMID:23607092
Metabolomic analysis of complex chinese remedies: examples of induced nephrotoxicity in the mouse from a series of remedies containing aristolochic Acid. PMID:23606874
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool. PMID:23586463
Evaluation of Pacific white shrimp (Litopenaeus vannamei) health during a superintensive aquaculture growout using NMR-based metabolomics. PMID:23555690
Computational mass spectrometry for small molecules. PMID:23453222
Sum of the parts: mass spectrometry-based metabolomics. PMID:23442130
Metabolomics in epidemiology: sources of variability in metabolite measurements and implications. PMID:23396963
Urinary metabolomic signature of esophageal cancer and Barrett's esophagus. PMID:23241138
Dietary biomarkers: advances, limitations and future directions. PMID:23237668
MetaboID: a graphical user interface package for assignment of 1H NMR spectra of bodyfluids and tissues. PMID:23232331
Global metabolic profiling of animal and human tissues via UPLC-MS. PMID:23222455
A mass spectrometric study for comparative analysis and evaluation of metabolite recovery from plasma by various solvent systems. PMID:23204928
Metabolomics: an essential tool to understand the function of peroxisome proliferator-activated receptor alpha. PMID:23197196
Reconciliation of metabolites and biochemical reactions for metabolic networks. PMID:23172809
HMDB 3.0--The Human Metabolome Database in 2013. PMID:23161693
Metabonomic analysis of water extracts from Chinese and American ginsengs by 1H nuclear magnetic resonance: identification of chemical profile for quality control. PMID:23140520
Metabolic profiling: are we en route to better diagnostic tests for cancer? PMID:23130920
MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data. PMID:23109552
LC-MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort. PMID:23078175
MetaboLights: towards a new COSMOS of metabolomics data management. PMID:23060735
Metabolomics: a novel approach to identify potential diagnostic biomarkers and pathogenesis in Alzheimer's disease. PMID:23054640
MolFind: a software package enabling HPLC/MS-based identification of unknown chemical structures. PMID:23039714
Online tools for bioinformatics analyses in nutrition sciences. PMID:22983844
Sample preparation of Mycobacterium tuberculosis extracts for nuclear magnetic resonance metabolomic studies. PMID:22971839
Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis. PMID:22882828
Is NMR metabolic profiling of spent embryo culture media useful to assist in vitro human embryo selection? PMID:22878530
Preclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders. PMID:22877223
Translating metabolomics to cardiovascular biomarkers. PMID:22824112
Delineating metabolic signatures of head and neck squamous cell carcinoma: phospholipase A2, a potential therapeutic target. PMID:22743333
Perspectives on systems biology applications in diabetic kidney disease. PMID:22733404
Borrelia burgdorferi harbors a transport system essential for purine salvage and mammalian infection. PMID:22710875
Exploration of serum metabolomic profiles and outcomes in women with metastatic breast cancer: a pilot study. PMID:22687601
PyMS: a Python toolkit for processing of gas chromatography-mass spectrometry (GC-MS) data. Application and comparative study of selected tools. PMID:22647087
Mass spectra-based framework for automated structural elucidation of metabolome data to explore phytochemical diversity. PMID:22645535
Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT. PMID:22615553
MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity. PMID:22591066
Multi-platform characterization of the human cerebrospinal fluid metabolome: a comprehensive and quantitative update. PMID:22546835
Development of Ecom₅₀ and retention index models for nontargeted metabolomics: identification of 1,3-dicyclohexylurea in human serum by HPLC/mass spectrometry. PMID:22489687
Serum metabolic profiling in inflammatory bowel disease. PMID:22488632
Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death. PMID:22485151
Gram-negative and Gram-positive bacterial infections give rise to a different metabolic response in a mouse model. PMID:22483232
Application of NMR metabolomics to search for human disease biomarkers. PMID:22480238
Investigation of chronic alcohol consumption in rodents via ultra-high-performance liquid chromatography-mass spectrometry based metabolite profiling. PMID:22446076
Assessment of the effect of high or low protein diet on the human urine metabolome as measured by NMR. PMID:22413065
Clinical metabolomics paves the way towards future healthcare strategies. PMID:22348240
The serum metabolite response to diet intervention with probiotic acidified milk in irritable bowel syndrome patients is indistinguishable from that of non-probiotic acidified milk by 1H NMR-based metabonomic analysis. PMID:22254002
Stable isotope-resolved metabolomics and applications for drug development. PMID:22212615
Helicobacter pylori relies primarily on the purine salvage pathway for purine nucleotide biosynthesis. PMID:22194455
Metabolomic high-content nuclear magnetic resonance-based drug screening of a kinase inhibitor library. PMID:22109519
LC-MS-based metabolomics. PMID:22041788
Metabolomics in the study of kidney diseases. PMID:22025087
Perspectives for Metabolomics in Human Nutrition: An Overview. PMID:21994483
The human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functions. PMID:21962087
Global urinary metabolic profiling procedures using gas chromatography-mass spectrometry. PMID:21959233
Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives. PMID:21949491
Metabolomics as a tool for cardiac research. PMID:21931361
Ratio analysis nuclear magnetic resonance spectroscopy for selective metabolite identification in complex samples. PMID:21894988
Metabolomic phenotyping of a cloned pig model. PMID:21859467
Deconvolution of chemical mixtures with high complexity by NMR consensus trace clustering. PMID:21848333
Identification of serum biomarkers of hepatocarcinoma through liquid chromatography/mass spectrometry-based metabonomic method. PMID:21833635
AMDORAP: non-targeted metabolic profiling based on high-resolution LC-MS. PMID:21702951
Radiation metabolomics and its potential in biodosimetry. PMID:21692691
The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses. PMID:21680948
MeRy-B: a web knowledgebase for the storage, visualization, analysis and annotation of plant NMR metabolomic profiles. PMID:21668943
Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst. PMID:21637195
Deconvolution of two-dimensional NMR spectra by fast maximum likelihood reconstruction: application to quantitative metabolomics. PMID:21526800
Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). PMID:21476605
Assay of the multiple energy-producing pathways of mammalian cells. PMID:21455318
Identification and quantification of metabolites in (1)H NMR spectra by Bayesian model selection. PMID:21398670
(1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system. PMID:21373841
Metabolic profiling of vitamin C deficiency in Gulo-/- mice using proton NMR spectroscopy. PMID:21360155
The human serum metabolome. PMID:21359215
Therapeutic paracetamol treatment in older persons induces dietary and metabolic modifications related to sulfur amino acids. PMID:21340541
Towards a point-of-care test for active tuberculosis: obstacles and opportunities. PMID:21326275
Hierarchical alignment and full resolution pattern recognition of 2D NMR spectra: application to nematode chemical ecology. PMID:21314130
Ultraperformance liquid chromatography-tandem mass spectrometry method for biomonitoring cooked meat carcinogens and their metabolites in human urine. PMID:21194225
In vivo NMR metabolic profiling of Fabrea salina reveals sequential defense mechanisms against ultraviolet radiation. PMID:21190674
The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research. PMID:21189865
Identification of urinary biomarkers of colon inflammation in IL10-/- mice using Short-Column LCMS metabolomics. PMID:21188174
metaXCMS: second-order analysis of untargeted metabolomics data. PMID:21174458
Metabolomic distinction and insights into the pathogenesis of human primary dilated cardiomyopathy. PMID:21155767
Metabolomics to unveil and understand phenotypic diversity between pathogen populations. PMID:21152055
Towards a knowledge-based Human Protein Atlas. PMID:21139605
Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PMID:21085649
NMR-spectroscopic analysis of mixtures: from structure to function. PMID:21071261
Simultaneous de novo identification of molecules in chemical mixtures by doubly indirect covariance NMR spectroscopy. PMID:21062057
Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research. PMID:20980656
Insulin sensitivity is reflected by characteristic metabolic fingerprints--a Fourier transform mass spectrometric non-targeted metabolomics approach. PMID:20976215
Early detection of recurrent breast cancer using metabolite profiling. PMID:20959483
MetAssimulo: simulation of realistic NMR metabolic profiles. PMID:20925910
Metabolic consequences of sepsis-induced acute lung injury revealed by plasma ¹H-nuclear magnetic resonance quantitative metabolomics and computational analysis. PMID:20889676
Quantitative analysis of blood plasma metabolites using isotope enhanced NMR methods. PMID:20879716
Using NMR metabolomics to investigate tricarboxylic acid cycle-dependent signal transduction in Staphylococcus epidermidis. PMID:20861019
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. PMID:20847263
HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. PMID:20823849
Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism. PMID:20823844
Quantitative proteomics and metabolomics analysis of normal human cerebrospinal fluid samples. PMID:20811074
Activity-based protein profiling for biochemical pathway discovery in cancer. PMID:20703252
Mass spectrometry-based metabolomics, analysis of metabolite-protein interactions, and imaging. PMID:20701590
Altered metabolism in cancer. PMID:20598111
Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex. PMID:20581821
Metabolic signatures of exercise in human plasma. PMID:20505214
Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery. PMID:20504069
NMR method for measuring carbon-13 isotopic enrichment of metabolites in complex solutions. PMID:20459129
MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data. PMID:20457745
Dealing with the unknown: metabolomics and metabolite atlases. PMID:20452782
Global metabolic profiling procedures for urine using UPLC-MS. PMID:20448546
Advances in NMR-based biofluid analysis and metabolite profiling. PMID:20379603
Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. PMID:20349993
Mass action stoichiometric simulation models: incorporating kinetics and regulation into stoichiometric models. PMID:20338839
Advances in Nuclear Magnetic Resonance for Drug Discovery. PMID:20333269
Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers. PMID:20331867
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. PMID:20300169
Xenobiotic metabolism: a view through the metabolometer. PMID:20232918
The Analysis of Multiple Genome Comparisons in Genus Escherichia and Its Application to the Discovery of Uncharacterised Metabolic Genes in Uropathogenic Escherichia coli CFT073. PMID:20204180
Metabolomic characterization of the salt stress response in Streptomyces coelicolor. PMID:20190082
Metabolomic analysis of human disease and its application to the eye. PMID:20157358
PlantMetabolomics.org: a web portal for plant metabolomics experiments. PMID:20147492
A statistically rigorous test for the identification of parent-fragment pairs in LC-MS datasets. PMID:20143830
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services. PMID:20047655
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research. PMID:20046865
Application of GC/MS-based metabonomic profiling in studying the lipid-regulating effects of Ginkgo biloba extract on diet-induced hyperlipidemia in rats. PMID:19960012
Physiochemical property space distribution among human metabolites, drugs and toxins. PMID:19958509
SMPDB: The Small Molecule Pathway Database. PMID:19948758
A role for the MS analysis of nucleic acids in the post-genomics age. PMID:19897384
The role of mass spectrometry-based metabolomics in medical countermeasures against radiation. PMID:19890938
Metabolomics: moving towards personalized medicine. PMID:19852788
rNMR: open source software for identifying and quantifying metabolites in NMR spectra. PMID:19821464
Monitoring dynamic changes in lymph metabolome of fasting and fed rats by electrospray ionization-ion mobility mass spectrometry (ESI-IMMS). PMID:19788315
GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle. PMID:19666713
Biomarker discovery in animal health and disease: the application of post-genomic technologies. PMID:19662203
Deconvoluting the 'omics' for organ transplantation. PMID:19644370
Web server suite for complex mixture analysis by covariance NMR. PMID:19634130
mSpecs: a software tool for the administration and editing of mass spectral libraries in the field of metabolomics. PMID:19624850
Hmrbase: a database of hormones and their receptors. PMID:19589147
Metabolomic analysis of human vitreous humor differentiates ocular inflammatory disease. PMID:19536306
Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response. PMID:19496611
The toxicity data landscape for environmental chemicals. PMID:19479008
Biomonitoring of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its carcinogenic metabolites in urine. PMID:19441775
MetaboAnalyst: a web server for metabolomic data analysis and interpretation. PMID:19429898
Spatiotemporal integration of molecular and anatomical data in virtual reality using semantic mapping. PMID:19421373
Database resources in metabolomics: an overview. PMID:19418229
How large is the metabolome? A critical analysis of data exchange practices in chemistry. PMID:19415114
Genomic and proteomic biomarkers for cancer: a multitude of opportunities. PMID:19406210
Predicting metabolic biomarkers of human inborn errors of metabolism. PMID:19401675
A PARACEST agent responsive to inner- and outer-sphere phosphate ester interactions for MRI applications. PMID:19317496
Automics: an integrated platform for NMR-based metabonomics spectral processing and data analysis. PMID:19291281
From differentiating metabolites to biomarkers. PMID:19277615
Prediction of interaction between small molecule and enzyme using AdaBoost. PMID:19219560
Clinical applications of metabolomics in oncology: a review. PMID:19147747
Molecular formula and METLIN Personal Metabolite Database matching applied to the identification of compounds generated by LC/TOF-MS. PMID:19137116
Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry. PMID:19081807
Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study. PMID:19057651
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PMID:19043545
MetaboMiner--semi-automated identification of metabolites from 2D NMR spectra of complex biofluids. PMID:19040747
Systematic NMR analysis of stable isotope labeled metabolite mixtures in plant and animal systems: coarse grained views of metabolic pathways. PMID:19030231
HMDB: a knowledgebase for the human metabolome. PMID:18953024
MS/MS spectral tag-based annotation of non-targeted profile of plant secondary metabolites. PMID:18939963
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. PMID:18846089
LC-MSsim--a simulation software for liquid chromatography mass spectrometry data. PMID:18842122
Building blocks for automated elucidation of metabolites: machine learning methods for NMR prediction. PMID:18817546
Presenting and exploring biological pathways with PathVisio. PMID:18817533
Metabolomics-based methods for early disease diagnostics. PMID:18785810
Self-consistent metabolic mixture analysis by heteronuclear NMR. Application to a human cancer cell line. PMID:18771235
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury. PMID:18769631
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. PMID:18667486
Application of metabolomics to cardiovascular biomarker and pathway discovery. PMID:18598890
Identification of metabolites with anticancer properties by computational metabolomics. PMID:18559081
Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques. PMID:18521184
Systems biology approaches for the study of multiple sclerosis. PMID:18505469
Analytical strategies for LC-MS-based targeted metabolomics. PMID:18502704
PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites. PMID:18487273
MassTRIX: mass translator into pathways. PMID:18442993
Formulating genome-scale kinetic models in the post-genome era. PMID:18319723
DrugBank: a knowledgebase for drugs, drug actions and drug targets. PMID:18048412
Method for determining molar concentrations of metabolites in complex solutions from two-dimensional 1H-13C NMR spectra. PMID:17985927
Use of NMR metabolomics to analyze the targets of D-cycloserine in mycobacteria: role of D-alanine racemase. PMID:17979227
The human microbiome project. PMID:17943116
The Edinburgh human metabolic network reconstruction and its functional analysis. PMID:17882155
LC-MS-based metabolomics in drug metabolism. PMID:17786640
A sex-specific metabolite identified in a marine invertebrate utilizing phosphorus-31 nuclear magnetic resonance. PMID:17712428
Shotgun metabolomics approach for the analysis of negatively charged water-soluble cellular metabolites from mouse heart tissue. PMID:17665876
Diagnostic pathology and laboratory medicine in the age of "omics": a paper from the 2006 William Beaumont Hospital Symposium on Molecular Pathology. PMID:17652635
The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi. PMID:17542926
HMDB: a knowledgebase for the human metabolome PubMed citations: 671.

671 articles citing: HMDB: a knowledgebase for the human metabolome

Trans- and Multigenerational Maternal Social Isolation Stress Programs the Blood Plasma Metabolome in the F3 Generation. PMID:35888696
Unlocking the Potential of the Human Microbiome for Identifying Disease Diagnostic Biomarkers. PMID:35885645
Untargeted Metabolomic Plasma Profiling of Emirati Dialysis Patients with Diabetes versus Non-Diabetic: A Pilot Study. PMID:35883517
NMR-Based Metabolomics Identify Metabolic Change in Spleen of Idiopathic Thrombocytopenic Purpura Patients. PMID:35736497
PeakForest: a multi-platform digital infrastructure for interoperable metabolite spectral data and metadata management. PMID:35699774
Automated Cancer Diagnostics via Analysis of Optical and Chemical Images by Deep and Shallow Learning. PMID:35629959
NMR-based metabolomic profiling can differentiate follicular lymphoma from benign lymph node tissues and may be predictive of outcome. PMID:35585165
Metabolomics Applied to Cord Serum in Preeclampsia Newborns: Implications for Neonatal Outcomes. PMID:35547553
Therapeutic hypothermia attenuates physiologic, histologic, and metabolomic markers of injury in a porcine model of acute respiratory distress syndrome. PMID:35510328
Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice. PMID:35448524
MetaboListem and TABoLiSTM: Two Deep Learning Algorithms for Metabolite Named Entity Recognition. PMID:35448463
Detection of electrostatic molecular binding using the water proton signal. PMID:35394084
The influence of cystathionine on neurochemical quantification in brain tumor in vivo MR spectroscopy. PMID:35381117
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle. PMID:35365625
Metabolomics Study of Different Germplasm Resources for Three Polygonatum Species Using UPLC-Q-TOF-MS/MS. PMID:35360317
Identifying HSV-1 Inhibitors from Natural Compounds via Virtual Screening Targeting Surface Glycoprotein D. PMID:35337158
Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines. PMID:35315332
Acute aerobic exercise reveals that FAHFAs distinguish the metabolomes of overweight and normal-weight runners. PMID:35192550
Metabolomics in endometriosis: challenges and perspectives for future studies. PMID:35128453
A clinician's guide to omics resources in dermatology. PMID:35104371
Experimental determination of Escherichia coli biomass composition for constraint-based metabolic modeling. PMID:35085271
A Metabonomic View on Wilms Tumor by High-Resolution Magic-Angle Spinning Nuclear Magnetic Resonance Spectroscopy. PMID:35054324
Organ-Specific Metabolome Deciphering Cell Pathways to Cope with Mercury in Wild Fish (Golden Grey Mullet Chelon auratus). PMID:35011185
Gut Microbiota as a Source of Uremic Toxins. PMID:35008909
HMDB 5.0: the Human Metabolome Database for 2022. PMID:34986597
Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein. PMID:34971947
Serum Metabolic Profiles Based on Nuclear Magnetic Resonance Spectroscopy among Patients with Deep Vein Thrombosis and Healthy Controls. PMID:34940632
The effect of sample age on the metabolic information extracted from formalin-fixed and paraffin embedded tissue samples using desorption electrospray ionization mass spectrometry imaging. PMID:34939055
In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure. PMID:34930451
A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation. PMID:34858137
Bacterial challenge-associated metabolic phenotypes in Hermetia illucens defining nutritional and functional benefits. PMID:34857836
Integration of Choline Chloride-Based Natural Deep Eutectic Solvents and Macroporous Resin for Green Production of Enriched Oil Palm Flavonoids as Natural Wound Healing Agents. PMID:34829674
Metabolomic and lipidomic characterization of an X-chromosome deletion disorder in neural progenitor cells by UHPLC-HRMS. PMID:34820667
Glycan Biosynthesis Ability of Gut Microbiota Increased in Primary Hypertension Patients Taking Antihypertension Medications and Potentially Promoted by Macrophage-Adenosine Monophosphate-Activated Protein Kinase. PMID:34803940
A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria. PMID:34799606
The Investigation of Metabonomic Pathways of Serum of Iranian Women with Recurrent Miscarriage Using 1H NMR. PMID:34778450
Metabolite Identification Using Infrared Ion Spectroscopy─Novel Biomarkers for Pyridoxine-Dependent Epilepsy. PMID:34756024
Precise pathological classification of non-small cell lung adenocarcinoma and squamous carcinoma based on an integrated platform of targeted metabolome and lipidome. PMID:34729658
Serum metabolomics of end-stage renal disease patients with depression: potential biomarkers for diagnosis. PMID:34723750
Human serum metabolomic analysis reveals progression for high blood pressure in type 2 diabetes mellitus. PMID:34711543
Metabolic Profiling and Metabolites Fingerprints in Human Hypertension: Discovery and Potential. PMID:34677402
Metabolomics and Inflammatory Mediator Profiling for the Differentiation of Life-Threatening and Non-Severe Appendicitis in the Pediatric Population. PMID:34677379
Glutamine restores mitochondrial respiration in bleomycin-injured epithelial cells. PMID:34634441
Computational Prediction of Chemical Tools for Identification and Validation of Synthetic Lethal Interaction Networks. PMID:34590285
Biofluid Metabolomics of Mice Exposed to External Low-Dose Rate Radiation in a Novel Irradiation System, the Variable Dose-Rate External 137Cs Irradiator. PMID:34585931
Food Composition Databases: Does It Matter to Human Health? PMID:34444976
Expanding Urinary Metabolite Annotation through Integrated Mass Spectral Similarity Networking. PMID:34436864
Impact of Weaning and Maternal Immune Activation on the Metabolism of Pigs. PMID:34336923
Metabolomic biomarkers of low BMD: a systematic review. PMID:34309694
Application of Metabolomics to Identify Hepatic Biomarkers of Foie Gras Qualities in Duck. PMID:34305649
NMR Spectroscopy for Protein Higher Order Structure Similarity Assessment in Formulated Drug Products. PMID:34299526
Logistic matrix factorisation and generative adversarial neural network-based method for predicting drug-target interactions. PMID:34297278
Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine. PMID:34257858
Decreased MEF2A Expression Regulated by Its Enhancer Methylation Inhibits Autophagy and May Play an Important Role in the Progression of Alzheimer's Disease. PMID:34220439
NFnetFu: A novel workflow for microbiome data fusion. PMID:34216888
In silico prediction of chemical-induced hematotoxicity with machine learning and deep learning methods. PMID:34196933
Plasma metabolomic profiles as affected by diet and stress in Spanish goats. PMID:34131197
Application of Volatilome Analysis to the Diagnosis of Mycobacteria Infection in Livestock. PMID:34109231
Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions. PMID:34043632
The gut microbiome in pancreatogenic diabetes differs from that of Type 1 and Type 2 diabetes. PMID:34040023
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights. PMID:34019663
Advanced Diagnostic Technology of Volatile Organic Compounds Real Time analysis Analysis From Exhaled Breath of Gastric Cancer Patients Using Proton-Transfer-Reaction Time-of-Flight Mass Spectrometry. PMID:33996531
Quantum Chemistry Calculations for Metabolomics. PMID:33979149
Quo Vadis Caenorhabditis elegans Metabolomics-A Review of Current Methods and Applications to Explore Metabolism in the Nematode. PMID:33947148
Precision Oncology via NMR-Based Metabolomics: A Review on Breast Cancer. PMID:33925233
Artificial intelligence to deep learning: machine intelligence approach for drug discovery. PMID:33844136
NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. PMID:33843271
SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome. PMID:33807773
Benchmarking Non-Targeted Metabolomics Using Yeast-Derived Libraries. PMID:33802096
A Metabolomic Approach to Beer Characterization. PMID:33800512
Nutrient availability regulates proline/alanine transporters in Trypanosoma brucei. PMID:33745971
Detecting the effects of predator-induced stress on the global metabolism of an ungulate prey using fecal metabolomic fingerprinting. PMID:33731769
Collagen I Fibrous Substrates Modulate the Proliferation and Secretome of Estrogen Receptor-Positive Breast Tumor Cells in a Hormone-Restricted Microenvironment. PMID:33688723
Plasma Metabolic Profiling of Pediatric Sepsis in a Chinese Cohort. PMID:33659257
Sudden Infant Death Syndrome: Beyond Risk Factors. PMID:33652660
Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics. PMID:33643071
Magnetic resonance spectroscopy for the study of cns malignancies. PMID:33632416
Metabolic dysfunction in pregnancy: Fingerprinting the maternal metabolome using proton nuclear magnetic resonance spectroscopy. PMID:33532625
Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI. PMID:33514438
A dynamic multi-tissue model to study human metabolism. PMID:33483512
Metabolomics Analysis of the Effect of Glutamic Acid on Monacolin K Synthesis in Monascus purpureus. PMID:33391237
Systems View of Deconditioning During Spaceflight Simulation in the PlanHab Project: The Departure of Urine 1 H-NMR Metabolomes From Healthy State in Young Males Subjected to Bedrest Inactivity and Hypoxia. PMID:33364971
Metabolite Characterization and Correlations with Antioxidant and Wound Healing Properties of Oil Palm (Elaeis guineensis Jacq.) Leaflets via 1H-NMR-Based Metabolomics Approach. PMID:33265992
Urinary Metabonomic Profiling Discriminates Between Children with Autism and Their Healthy Siblings. PMID:33237888
Chemotherapeutic efficacy of cucurmosin for pancreatic cancer as an alternative of gemcitabine: a comparative metabolomic study. PMID:33224818
1H-NMR-Based Analysis for Exploring Knee Synovial Fluid Metabolite Changes after Local Cryotherapy in Knee Arthritis Patients. PMID:33202890
Design and Characterisation of a Randomized Food Intervention That Mimics Exposure to a Typical UK Diet to Provide Urine Samples for Identification and Validation of Metabolite Biomarkers of Food Intake. PMID:33195362
Insights in Osteosarcoma by Proton Nuclear Magnetic Resonance Serum Metabonomics. PMID:33178572
The utility of nuclear magnetic resonance spectroscopy in assisted reproduction. PMID:33142083
Metabolomics Pilot Study Identifies Desynchronization of 24-H Rhythms and Distinct Intra-patient Variability Patterns in Critical Illness: A Preliminary Report. PMID:33123071
Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti. PMID:32948809
Salivary metabolite levels in perinatally HIV-infected youth with periodontal disease. PMID:32915320
Lipidomic UPLC-MS/MS Profiles of Normal-Appearing White Matter Differentiate Primary and Secondary Progressive Multiple Sclerosis. PMID:32911763
Addressing the batch effect issue for LC/MS metabolomics data in data preprocessing. PMID:32807888
Excretory/Secretory Metabolome of the Zoonotic Roundworm Parasite Toxocara canis. PMID:32781793
Discovery and predictive modeling of urine microbiome, metabolite and cytokine biomarkers in hospitalized patients with community acquired pneumonia. PMID:32770049
Metabolic response of blood vessels to TNFα. PMID:32749215
Identifying unknown metabolites using NMR-based metabolic profiling techniques. PMID:32681152
Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia. PMID:32668598
A quest to identify suitable organic tracers for estimating children's dust ingestion rates. PMID:32661335
Effects of Genetic Variation on Urinary Small Molecule Signatures of Mice after Exposure to Ionizing Radiation: A Study of p53 Deficiency. PMID:32521675
The Bovine Metabolome. PMID:32517015
The plant cuticle regulates apoplastic transport of salicylic acid during systemic acquired resistance. PMID:32494705
Detailed Structural Characterization of the Lipooligosaccharide from the Extracellular Membrane Vesicles of Shewanella vesiculosa HM13. PMID:32349432
Cardiovascular Risk and Resilience Among Black Adults: Rationale and Design of the MECA Study. PMID:32340530
Computational pipeline for estimation of small-molecule T1 relaxation times. PMID:32339979
Nuclear Magnetic Resonance Metabolomics Reveals Qualitative and Quantitative Differences in the Composition of Human Breast Milk and Milk Formulas. PMID:32230787
Improving lipid mapping in Genome Scale Metabolic Networks using ontologies. PMID:32215752
Milk yield, milk composition, and milk metabolomics of dairy goats intramammary-challenged with lipopolysaccharide under heat stress conditions. PMID:32193484
A Solution to Antifolate Resistance in Group B Streptococcus: Untargeted Metabolomics Identifies Human Milk Oligosaccharide-Induced Perturbations That Result in Potentiation of Trimethoprim. PMID:32184236
MMHub, a database for the mulberry metabolome. PMID:32159764
Deregulation of the Purine Pathway in Pre-Transplant Liver Biopsies Is Associated with Graft Function and Survival after Transplantation. PMID:32151072
An Integrated Multi-Omics Analysis Defines Key Pathway Alterations in a Diet-Induced Obesity Mouse Model. PMID:32106514
Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis. PMID:32025330
Proton magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations. PMID:32022964
Predicting octanol/water partition coefficients for the SAMPL6 challenge using the SM12, SM8, and SMD solvation models. PMID:32002781
Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics. PMID:31984744
Delineating cell behavior and metabolism of non-melanoma skin cancer in vitro. PMID:31970645
Magnetic Resonance Microscopy at Cellular Resolution and Localised Spectroscopy of Medicago truncatula at 22.3 Tesla. PMID:31969628
From Samples to Insights into Metabolism: Uncovering Biologically Relevant Information in LC-HRMS Metabolomics Data. PMID:31861212
Analysis of Postdeployment Serum Samples Identifies Potential Biomarkers of Exposure to Burn Pits and Other Environmental Hazards. PMID:31800450
Untargeted Metabolomics-Based Screening Method for Inborn Errors of Metabolism using Semi-Automatic Sample Preparation with an UHPLC- Orbitrap-MS Platform. PMID:31779119
Mechanisms underlying Eugenia mattosii D. Legrand leaves extract, fractions and compounds induce relaxation of the aorta from normotensive and hypertensive rats. PMID:31763123
Identification of a radical SAM enzyme involved in the synthesis of archaeosine. PMID:31740832
Lipidomics by HILIC-Ion Mobility-Mass Spectrometry. PMID:31729657
Influence of Drying Method on NMR-Based Metabolic Profiling of Human Cell Lines. PMID:31683565
Classifying the antibody-negative NMO syndromes: Clinical, imaging, and metabolomic modeling. PMID:31659123
Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulation. PMID:31637787
NMR-based metabolic profiling and comparison of Japanese persimmon cultivars. PMID:31628382
Post-periodontal surgery propounds early repair salivary biomarkers by 1H NMR based metabolomics. PMID:31612356
Metabolomic Perspectives in Antiblastic Cardiotoxicity and Cardioprotection. PMID:31590338
An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs. PMID:31587113
Monosodium Glutamate (MSG) Renders Alkalinizing Properties and Its Urinary Metabolic Markers of MSG Consumption in Rats. PMID:31569818
The metaRbolomics Toolbox in Bioconductor and beyond. PMID:31548506
Structural Elucidation of Bisulfite Adducts to Pseudouridine That Result in Deletion Signatures during Reverse Transcription of RNA. PMID:31538776
15-Hydroperoxy-PGE2 : Intermediate in Mammalian and Algal Prostaglandin Biosynthesis. PMID:31529599
Tools for Enhanced NMR-Based Metabolomics Analysis. PMID:31463858
Screening of Microbial Volatile Organic Compounds for Detection of Disease in Cattle: Development of Lab-scale Method. PMID:31431630
NMR Based Metabolomic Analysis of Health Promoting Phytochemicals in Lentils. PMID:31412621
Crystal structure of zymonic acid and a redetermination of its precursor, pyruvic acid. PMID:31391982
Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress. PMID:31348603
NMR Spectroscopy for Metabolomics Research. PMID:31252628
Deciphering the metabolic perturbation in hepatic alveolar echinococcosis: a 1H NMR-based metabolomics study. PMID:31196218
Metabolomic signatures of asthma-COPD overlap (ACO) are different from asthma and COPD. PMID:31165288
Plasma metabolomic profiling of proliferative diabetic retinopathy. PMID:31160916
NMR metabolome of Borrelia burgdorferi in vitro and in vivo in mice. PMID:31142787
13C Labeling of Nematode Worms to Improve Metabolome Coverage by Heteronuclear Nuclear Magnetic Resonance Experiments. PMID:31106208
Addressing the pitfalls when designing intervention studies to discover and validate biomarkers of habitual dietary intake. PMID:31049735
High-resolution MS/MS metabolomics by data-independent acquisition reveals urinary metabolic alteration in experimental colitis. PMID:31041724
Microdialysis Workflow for Metabotyping Superficial Pathologies: Application to Burn Injury. PMID:31021084
A pilot metabolomics study of tuberculosis immune reconstitution inflammatory syndrome. PMID:31009738
Identification of atherosclerosis-related prioritizing metabolites based on a multi-omics composite network. PMID:30988716
Prioritization of candidate metabolites for postmenopausal osteoporosis using multi-omics composite network. PMID:30936988
Biomarkers of food intake for nuts and vegetable oils: an extensive literature search. PMID:30923582
Challenges in Identifying the Dark Molecules of Life. PMID:30883183
Identification of Key Metabolites for Acute Lung Injury in Patients with Sepsis. PMID:30847314
Liquid Chromatography-Mass Spectrometry-Based Metabolomics of Nonhuman Primates after 4 Gy Total Body Radiation Exposure: Global Effects and Targeted Panels. PMID:30843397
RANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies. PMID:30830432
Metabolomic identification of diagnostic serum-based biomarkers for advanced stage melanoma. PMID:30830422
Organic washes of tissue sections for comprehensive analysis of small molecule metabolites by MALDI MS imaging of rat brain following status epilepticus. PMID:30830331
Quality Control of Therapeutic Peptides by 1H NMR HiFSA Sequencing. PMID:30793905
Automated evaluation of consistency within the PubChem Compound database. PMID:30778259
Metabolomics Approaches for the Diagnosis and Understanding of Kidney Diseases. PMID:30769897
Mapping Lipid Fragmentation for Tailored Mass Spectral Libraries. PMID:30756325
Heat stress modifies the lactational performances and the urinary metabolomic profile related to gastrointestinal microbiota of dairy goats. PMID:30735497
mzTab-M: A Data Standard for Sharing Quantitative Results in Mass Spectrometry Metabolomics. PMID:30688441
Metabolomics of Pregnancy Complications: Emerging Application of Maternal Hair. PMID:30662903
Dimethyl fumarate treatment induces lipid metabolism alterations that are linked to immunological changes. PMID:30656182
Leveraging Multilayered "Omics" Data for Atopic Dermatitis: A Road Map to Precision Medicine. PMID:30631320
Metabolomics and Age-Related Macular Degeneration. PMID:30591665
A robust intracellular metabolite extraction protocol for human neutrophil metabolic profiling. PMID:30571714
A Simple and Convenient Synthesis of Unlabeled and 13C-Labeled 3-(3-Hydroxyphenyl)-3-Hydroxypropionic Acid and Its Quantification in Human Urine Samples. PMID:30469313
The proteomic and metabolomic characterization of exercise-induced sweat for human performance monitoring: A pilot investigation. PMID:30383773
An automated framework for NMR chemical shift calculations of small organic molecules. PMID:30367288
Analysis of the Rumen Microbiome and Metabolome to Study the Effect of an Antimethanogenic Treatment Applied in Early Life of Kid Goats. PMID:30356690
Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells. PMID:30349315
Hydroxyurea Treated β-Thalassemia Children Demonstrate a Shift in Metabolism Towards Healthy Pattern. PMID:30310134
Profiling the Metabolism of Human Cells by Deep 13C Labeling. PMID:30270114
PhytoMolecularTasteDB: An integrative database on the "molecular taste" of Indian medicinal plants. PMID:30246068
900MHz 1H-/13C-NMR analysis of 2-hydroxyglutarate and other brain metabolites in human brain tumor tissue extracts. PMID:30192797
Nonhuman Primates with Acute Radiation Syndrome: Results from a Global Serum Metabolomics Study after 7.2 Gy Total-Body Irradiation. PMID:30183511
Altered Metabolic Profile of Triglyceride-Rich Lipoproteins in Gut-Lymph of Rodent Models of Sepsis and Gut Ischemia-Reperfusion Injury. PMID:30182310
The Omics Revolution Continues: The Maturation of High-Throughput Biological Data Sources. PMID:30157526
Prenatal Maternal Stress from a Natural Disaster Alters Urinary Metabolomic Profiles in Project Ice Storm Participants. PMID:30154530
Applications of Parametrized NMR Spin Systems of Small Molecules. PMID:30125102
Identification of Urine Metabolites as Biomarkers of Early Lyme Disease. PMID:30111850
Global metabolic changes induced by plant-derived pyrrolizidine alkaloids following a human poisoning outbreak and in a mouse model. PMID:30090460
Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury. PMID:30069831
NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer. PMID:30016349
High-Throughput Metabolomics by 1D NMR. PMID:29999221
Effect of Tumor Relevant Acidic Environment in the Interaction of a N-hydroxyindole-2-Carboxylic Derivative with the Phospholipid Bilayer. PMID:29987655
A unique model for SDH-deficient GIST: an endocrine-related cancer. PMID:29967109
Robust imaging and gene delivery to study human lymphoblastoid cell lines. PMID:29925960
Metabolomic Profiling of Plasma Samples from Women with Recurrent Spontaneous Abortion. PMID:29898462
Tocotrienol-Rich Fraction of Palm Oil Improves Behavioral Impairments and Regulates Metabolic Pathways in AβPP/PS1 Mice. PMID:29889072
Reverse Screening Methods to Search for the Protein Targets of Chemopreventive Compounds. PMID:29868550
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome. PMID:29851973
In-Vivo NMR Spectroscopy: A Powerful and Complimentary Tool for Understanding Environmental Toxicity. PMID:29795000
Lipidome Evolution in Mammalian Tissues. PMID:29762743
Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson's Disease Reveals Distinct Metabolic Profiles. PMID:29762036
Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. PMID:29742587
Evaluation of targeted and untargeted effects-based monitoring tools to assess impacts of contaminants of emerging concern on fish in the South Platte River, CO. PMID:29715690
Cardiovascular Metabolomics. PMID:29700070
A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence. PMID:29679203
A prototypic small molecule database for bronchoalveolar lavage-based metabolomics. PMID:29664467
Discrimination between the human prostate normal and cancer cell exometabolome by GC-MS. PMID:29615722
Bayesian estimation of the number of protonation sites for urinary metabolites from NMR spectroscopic data. PMID:29606928
Route of Glucose Uptake in the Group a Streptococcus Impacts SLS-Mediated Hemolysis and Survival in Human Blood. PMID:29594067
Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer. PMID:29582397
GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells. PMID:29562689
Promises and pitfalls of untargeted metabolomics. PMID:29536203
IntLIM: integration using linear models of metabolomics and gene expression data. PMID:29506475
Borrelia burgdorferi genes, bb0639-0642, encode a putative putrescine/spermidine transport system, PotABCD, that is spermidine specific and essential for cell survival. PMID:29476656
Differences in Urinary Amino Acid Patterns in Individuals with Different Types of Urological Tumor Urinary Amino Acid Patterns as Markers of Urological Tumors. PMID:29475932
RaMP: A Comprehensive Relational Database of Metabolomics Pathways for Pathway Enrichment Analysis of Genes and Metabolites. PMID:29470400
Identification of an algal xylan synthase indicates that there is functional orthology between algal and plant cell wall biosynthesis. PMID:29460505
From Diabetes Care to Diabetes Cure-The Integration of Systems Biology, eHealth, and Behavioral Change. PMID:29403436
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation. PMID:29330507
Unique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis. PMID:29291380
Untargeted serum metabonomics study of psoriasis vulgaris based on ultra-performance liquid chromatography coupled to mass spectrometry. PMID:29221177
Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease. PMID:29208041
Volatile organic metabolites identify patients with gastric carcinoma, gastric ulcer, or gastritis and control patients. PMID:29200968
Postmortem 1H-MRS-Detection of Ketone Bodies and Glucose in Diabetic Ketoacidosis. PMID:29170817
HMDB 4.0: the human metabolome database for 2018. PMID:29140435
Longitudinal serum metabolomics evaluation of trastuzumab and everolimus combination as pre-operative treatment for HER-2 positive breast cancer patients. PMID:29137365
Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level Susceptibility. PMID:29109158
Non-invasively predicting differentiation of pancreatic cancer through comparative serum metabonomic profiling. PMID:29096620
Modelling of Hydrophilic Interaction Liquid Chromatography Stationary Phases Using Chemometric Approaches. PMID:29064436
Deciphering lipid structures based on platform-independent decision rules. PMID:29058722
Spin System Modeling of Nuclear Magnetic Resonance Spectra for Applications in Metabolomics and Small Molecule Screening. PMID:29058410
Use of Metabolomics in Improving Assessment of Dietary Intake. PMID:29038146
Identification and causes of metabonomic difference between orthotopic and subcutaneous xenograft of pancreatic cancer. PMID:28977862
Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig. PMID:28955207
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study. PMID:28936587
Large-scale Metabolomic Analysis Reveals Potential Biomarkers for Early Stage Coronary Atherosclerosis. PMID:28924163
Serum lysophospholipid levels are altered in dyslipidemic hamsters. PMID:28874705
Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG. PMID:28844900
Untargeted metabolomic analysis and pathway discovery in perinatal asphyxia and hypoxic-ischaemic encephalopathy. PMID:28840775
The metabolomics of psoriatic disease. PMID:28824870
Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome. PMID:28821301
Metabolic profiling of murine plasma reveals eicosapentaenoic acid metabolites protecting against endothelial activation and atherosclerosis. PMID:28771708
Diagnosis of coinfection by schistosomiasis and viral hepatitis B or C using 1H NMR-based metabonomics. PMID:28763497
Microscale Mass Spectrometry Analysis of Extracellular Metabolites in Live Multicellular Tumor Spheroids. PMID:28753268
NMR analysis reveals significant differences in the plasma metabolic profiles of Niemann Pick C1 patients, heterozygous carriers, and healthy controls. PMID:28740230
biochem4j: Integrated and extensible biochemical knowledge through graph databases. PMID:28708831
Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment. PMID:28706260
Use of fecal volatile organic compound analysis to discriminate between non-vaccinated and BCG-Vaccinated cattle prior to and after Mycobacterium bovis challenge. PMID:28686691
Screening Specific Biomarkers of Herbs Using a Metabolomics Approach: A Case Study of Panax ginseng. PMID:28676690
Analysis of Stable Isotope Assisted Metabolomics Data Acquired by High Resolution Mass Spectrometry. PMID:28674558
Development and Validation of a High-Throughput Mass Spectrometry Based Urine Metabolomic Test for the Detection of Colonic Adenomatous Polyps. PMID:28640228
Plasma metabolome and skin proteins in Charcot-Marie-Tooth 1A patients. PMID:28575008
"Gestaltomics": Systems Biology Schemes for the Study of Neuropsychiatric Diseases. PMID:28536537
Unique identifiers for small molecules enable rigorous labeling of their atoms. PMID:28534867
Livestock metabolomics and the livestock metabolome: A systematic review. PMID:28531195
Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration. PMID:28507131
A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source. PMID:28496395
Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia. PMID:28424077
Assessment of metabolic phenotypic variability in children's urine using 1H NMR spectroscopy. PMID:28422130
Cytoskeletal stability and metabolic alterations in primary human macrophages in long-term microgravity. PMID:28419128
Elucidation of the complex metabolic profile of cerebrospinal fluid using an untargeted biochemical profiling assay. PMID:28412083
The Importance of Endophenotypes to Evaluate the Relationship between Genotype and External Phenotype. PMID:28241430
A Comprehensive Analysis of Metabolomics and Transcriptomics in Cervical Cancer. PMID:28225065
A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation. PMID:28220056
β-Thalassemia Patients Revealed a Significant Change of Untargeted Metabolites in Comparison to Healthy Individuals. PMID:28198811
Impact of a cafeteria diet and daily physical training on the rat serum metabolome. PMID:28192465
Metabolite profiling of infection-associated metabolic markers of onchocerciasis. PMID:28188804
Metabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegans. PMID:28177875
LIQUID: an-open source software for identifying lipids in LC-MS/MS-based lipidomics data. PMID:28158427
NMR-Based Metabolic Profiling of Field-Grown Leaves from Sugar Beet Plants Harbouring Different Levels of Resistance to Cercospora Leaf Spot Disease. PMID:28134762
Lipidome determinants of maximal lifespan in mammals. PMID:28127055
Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. PMID:28112165
Ultra high performance liquid chromatography-high resolution mass spectrometry plasma lipidomics can distinguish between canine breeds despite uncontrolled environmental variability and non-standardized diets. PMID:28111530
Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole‑time‑of‑flight mass spectrometry. PMID:28098892
Distinguishing Benign from Malignant Pancreatic and Periampullary Lesions Using Combined Use of ¹H-NMR Spectroscopy and Gas Chromatography-Mass Spectrometry. PMID:28098776
A plasma metabolomic signature discloses human breast cancer. PMID:28076849
Considerations when choosing a genetic model organism for metabolomics studies. PMID:28025166
A Systematic Evaluation of Blood Serum and Plasma Pre-Analytics for Metabolomics Cohort Studies. PMID:27929400
Quorum Sensing Coordinates Cooperative Expression of Pyruvate Metabolism Genes To Maintain a Sustainable Environment for Population Stability. PMID:27923919
Molecular Approaches to Screen Bioactive Compounds from Endophytic Fungi. PMID:27895623
Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease. PMID:27889911
Electrospray deposition device used to precisely control the matrix crystal to improve the performance of MALDI MSI. PMID:27885266
Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models. PMID:27784287
Noninvasive Recognition and Biomarkers of Early Allergic Asthma in Cats Using Multivariate Statistical Analysis of NMR Spectra of Exhaled Breath Condensate. PMID:27764146
Metabolomic profiling of breast tumors using ductal fluid. PMID:27748798
Leucine-rich diet alters the 1H-NMR based metabolomic profile without changing the Walker-256 tumour mass in rats. PMID:27716121
Metabolomics and Cheminformatics Analysis of Antifungal Function of Plant Metabolites. PMID:27706030
Kidney Tissue Targeted Metabolic Profiling of Unilateral Ureteral Obstruction Rats by NMR. PMID:27695416
Time-resolved metabolomics analysis of individual differences during the early stage of lipopolysaccharide-treated rats. PMID:27695004
Theoretical investigation of loratadine reactivity in order to understand its degradation properties: DFT and MD study. PMID:27640160
Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways. PMID:27625019
Metabolomic profiling of brain from infants who died from Sudden Infant Death Syndrome reveals novel predictive biomarkers. PMID:27608295
An Untargeted Metabolomics Approach to Characterize Short-Term and Long-Term Metabolic Changes after Bariatric Surgery. PMID:27584017
The future of NMR-based metabolomics. PMID:27580257
Plasma Biomarkers for Monitoring Brain Pathophysiology in FMR1 Premutation Carriers. PMID:27570505
Plasma metabolic profile delineates roles for neurodegeneration, pro-inflammatory damage and mitochondrial dysfunction in the FMR1 premutation. PMID:27555610
A quantitative metabolomics profiling approach for the noninvasive assessment of liver histology in patients with chronic hepatitis C. PMID:27539580
Early detection of diabetic kidney disease: Present limitations and future perspectives. PMID:27525056
Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel. PMID:27501104
Animal-Free Chemical Safety Assessment. PMID:27493630
Functional characterization of the water-soluble organic carbon of size-fractionated aerosol in the southern Mississippi Valley. PMID:27471518
Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics. PMID:27471436
Preterm neonatal urinary renal developmental and acute kidney injury metabolomic profiling: an exploratory study. PMID:27435284
Use of Plasma Metabolomics to Identify Diagnostic Biomarkers for Early Stage Epithelial Ovarian Cancer. PMID:27390602
Biomonitoring in the Era of the Exposome. PMID:27385067
Characterization of water-soluble organic matter in urban aerosol by 1H-NMR spectroscopy. PMID:27313488
Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation. PMID:27239563
Protein Disulfide Levels and Lens Elasticity Modulation: Applications for Presbyopia. PMID:27233034
Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics. PMID:27231903
The Effect of Gestational and Lactational Age on the Human Milk Metabolome. PMID:27213440
Metagenomics, Metatranscriptomics, and Metabolomics Approaches for Microbiome Analysis. PMID:27199545
Stress transgenerationally programs metabolic pathways linked to altered mental health. PMID:27188285
Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study. PMID:27172772
Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain. PMID:27142336
Biomarker Discovery and Translation in Metabolomics. PMID:27134822
Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare. PMID:27130220
Metabolomic patterns associated to QTc interval in shiftworkers: an explorative analysis. PMID:27121294
Characterisation of the main drivers of intra- and inter- breed variability in the plasma metabolome of dogs. PMID:27065761
Metabonomic changes from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma in tissues from rats. PMID:27019331
HNdb: an integrated database of gene and protein information on head and neck squamous cell carcinoma. PMID:27013077
Integrated metabolomics and metagenomics analysis of plasma and urine identified microbial metabolites associated with coronary heart disease. PMID:26932197
Integrative Analysis of Multi-omics Data for Discovery and Functional Studies of Complex Human Diseases. PMID:26915271
The Basics of Bacteriuria: Strategies of Microbes for Persistence in Urine. PMID:26904513
Ion mobility mass spectrometry enhances low-abundance species detection in untargeted lipidomics. PMID:26900387
Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer. PMID:26880804
Using "Omics" and Integrated Multi-Omics Approaches to Guide Probiotic Selection to Mitigate Chytridiomycosis and Other Emerging Infectious Diseases. PMID:26870025
The Impact of Ischemia/Reperfusion Injury on Liver Allografts from Deceased after Cardiac Death versus Deceased after Brain Death Donors. PMID:26863224
Fragmentation trees reloaded. PMID:26839597
Lipidomics comparing DCD and DBD liver allografts uncovers lysophospholipids elevated in recipients undergoing early allograft dysfunction. PMID:26635289
Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network. PMID:26598063
Ambiguity of non-systematic chemical identifiers within and between small-molecule databases. PMID:26579214
Dissecting Proton Delocalization in an Enzyme's Hydrogen Bond Network with Unnatural Amino Acids. PMID:26571340
Identification of phosphatidylcholine and lysophosphatidylcholine as novel biomarkers for cervical cancers in a prospective cohort study. PMID:26566624
Quality assurance of metabolomics. PMID:26536290
ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs. PMID:26515061
Dereplication, sequencing and identification of peptidic natural products: from genome mining to peptidogenomics to spectral networks. PMID:26497201
Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase. PMID:26483191
ZINC 15--Ligand Discovery for Everyone. PMID:26479676
ChEBI in 2016: Improved services and an expanding collection of metabolites. PMID:26467479
Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools. PMID:26467476
Thermal Degradation of Small Molecules: A Global Metabolomic Investigation. PMID:26434689
Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected by Anaplasma phagocytophilum Infection in Tick Cells. PMID:26424601
Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort. PMID:26399231
New Technologies for Studying Biofilms. PMID:26350329
Development of metabolic and inflammatory mediator biomarker phenotyping for early diagnosis and triage of pediatric sepsis. PMID:26349677
An integrated network platform for contextual prioritization of drugs and pathways. PMID:26315485
Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics. PMID:26311249
Arteriovenous Blood Metabolomics: A Readout of Intra-Tissue Metabostasis. PMID:26244428
Global Metabolomic Identification of Long-Term Dose-Dependent Urinary Biomarkers in Nonhuman Primates Exposed to Ionizing Radiation. PMID:26230079
An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data. PMID:26195918
NMR-Based Metabolomics Separates the Distinct Stages of Disease in a Chronic Relapsing Model of Multiple Sclerosis. PMID:26155956
A statistical framework to model the meeting-in-the-middle principle using metabolomic data: application to hepatocellular carcinoma in the EPIC study. PMID:26130468
Metabolic networks in a porcine model of trauma and hemorrhagic shock demonstrate different control mechanism with carbohydrate pre-feed. PMID:26130247
Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review. PMID:26109927
Use of Charged Nanoparticles in NMR-Based Metabolomics for Spectral Simplification and Improved Metabolite Identification. PMID:26087125
Many InChIs and quite some feat. PMID:26081259
Revisiting Protocols for the NMR Analysis of Bacterial Metabolomes. PMID:26078915
Fungal endophytes of Vanilla planifolia across Réunion Island: isolation, distribution and biotransformation. PMID:26070309
Mass Spectrometry-based Lipidomics and Its Application to Biomedical Research. PMID:26064851
Metabolomics and renal disease. PMID:26050125
BioMiner: Paving the Way for Personalized Medicine. PMID:26005322
Defining the metabolome: size, flux, and regulation. PMID:26000853
Staphylococcus aureus metabolic adaptations during the transition from a daptomycin susceptibility phenotype to a daptomycin nonsusceptibility phenotype. PMID:25963986
Correction of precursor and product ion relative abundances in order to standardize CID spectra and improve Ecom50 accuracy for non-targeted metabolomics. PMID:25960696
Intracellular Accumulation of Glycine in Polyphosphate-Accumulating Organisms in Activated Sludge, a Novel Storage Mechanism under Dynamic Anaerobic-Aerobic Conditions. PMID:25956769
In vitro expansion of U87-MG human glioblastoma cells under hypoxic conditions affects glucose metabolism and subsequent in vivo growth. PMID:25934335
Systems biology of host-microbe metabolomics. PMID:25929487
Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit. PMID:25928796
Metabolite localization in living drosophila using High Resolution Magic Angle Spinning NMR. PMID:25892587
NMR/MS Translator for the Enhanced Simultaneous Analysis of Metabolomics Mixtures by NMR Spectroscopy and Mass Spectrometry: Application to Human Urine. PMID:25881480
Inflammaging and cancer: a challenge for the Mediterranean diet. PMID:25859884
A molecular structure matching approach to efficient identification of endogenous mammalian biochemical structures. PMID:25859612
Use of nuclear magnetic resonance-based metabolomics to characterize the biochemical effects of naphthalene on various organs of tolerant mice. PMID:25849086
Behavioural and molecular endophenotypes in psychotic disorders reveal heritable abnormalities in glutamatergic neurotransmission. PMID:25826115
Modelling the effect of SPION size in a stent assisted magnetic drug targeting system with interparticle interactions. PMID:25815370
Optimising chemical named entity recognition with pre-processing analytics, knowledge-rich features and heuristics. PMID:25810777
Recognition of chemical entities: combining dictionary-based and grammar-based approaches. PMID:25810767
Combining DI-ESI-MS and NMR datasets for metabolic profiling. PMID:25774104
Development of a metabolic biosignature for detection of early Lyme disease. PMID:25761869
Intake of hydrolyzed casein is associated with reduced body fat accretion and enhanced phase II metabolism in obesity prone C57BL/6J mice. PMID:25738501
Metabolomics and diabetes: analytical and computational approaches. PMID:25713200
Metabolomics beyond spectroscopic databases: a combined MS/NMR strategy for the rapid identification of new metabolites in complex mixtures. PMID:25674812
Untargeted UPLC-MS profiling pipeline to expand tissue metabolome coverage: application to cardiovascular disease. PMID:25664760
Metabolomics in the developmental origins of obesity and its cardiometabolic consequences. PMID:25631626
Qualitative characterization of the rat liver mitochondrial lipidome using all ion fragmentation on an Exactive benchtop Orbitrap MS. PMID:25631033
Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients. PMID:25611149
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. PMID:25599126
Muscular pre-conditioning using light-emitting diode therapy (LEDT) for high-intensity exercise: a randomized double-blind placebo-controlled trial with a single elite runner. PMID:25585514
Breath analysis as a potential and non-invasive frontier in disease diagnosis: an overview. PMID:25584743
Towards the fecal metabolome derived from moderate red wine intake. PMID:25532710
Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension. PMID:25530742
Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics. PMID:25521354
Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease. PMID:25424003
Metabolomic profiling in cattle experimentally infected with Mycobacterium avium subsp. paratuberculosis. PMID:25372282
Unified and isomer-specific NMR metabolomics database for the accurate analysis of (13)C-(1)H HSQC spectra. PMID:25333826
Plasma metabolomics in human pulmonary tuberculosis disease: a pilot study. PMID:25329995
Biomarkers for pancreatic cancer: recent achievements in proteomics and genomics through classical and multivariate statistical methods. PMID:25309068
An online system for metabolic network analysis. PMID:25267793
A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis. PMID:25253748
A systems approach to predict oncometabolites via context-specific genome-scale metabolic networks. PMID:25232952
TMDB: a literature-curated database for small molecular compounds found from tea. PMID:25224438
Metabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with Temozolomide. PMID:25222834
Prioritizing candidate disease metabolites based on global functional relationships between metabolites in the context of metabolic pathways. PMID:25153931
Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics. PMID:25120557
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression. PMID:25060643
Toward better annotation in plant metabolomics: isolation and structure elucidation of 36 specialized metabolites from Oryza sativa (rice) by using MS/MS and NMR analyses. PMID:25057267
A dedicated database system for handling multi-level data in systems biology. PMID:25053973
Emerging biomarkers and metabolomics for assessing toxic nephropathy and acute kidney injury (AKI) in neonatology. PMID:25013791
Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother-child cohort study. PMID:25012562
Improving peak detection in high-resolution LC/MS metabolomics data using preexisting knowledge and machine learning approach. PMID:25005748
The mzTab data exchange format: communicating mass-spectrometry-based proteomics and metabolomics experimental results to a wider audience. PMID:24980485
A review of applications of metabolomics in cancer. PMID:24958139
NMR-Based Milk Metabolomics. PMID:24957988
Metabonomic Response to Milk Proteins after a Single Bout of Heavy Resistance Exercise Elucidated by 1H Nuclear Magnetic Resonance Spectroscopy. PMID:24957889
Post-acquisition data processing for the screening of transformation products of different organic contaminants. Two-year monitoring of river water using LC-ESI-QTOF-MS and GCxGC-EI-TOF-MS. PMID:24952251
IIS--Integrated Interactome System: a web-based platform for the annotation, analysis and visualization of protein-metabolite-gene-drug interactions by integrating a variety of data sources and tools. PMID:24949626
Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose phosphate pathway in paraquat toxicity. PMID:24937102
Genomic and metabolomic profile associated to microalbuminuria. PMID:24918908
Evidence of a novel mevalonate pathway in archaea. PMID:24914732
Challenges in accurate quantitation of lysophosphatidic acids in human biofluids. PMID:24872406
Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness. PMID:24866127
Genetic regulation of mouse liver metabolite levels. PMID:24860088
Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry. PMID:24858467
Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. PMID:24856386
Urinary metabolite profiles in premature infants show early postnatal metabolic adaptation and maturation. PMID:24824288
Metabolomics analysis uncovers that dietary restriction buffers metabolic changes associated with aging in Caenorhabditis elegans. PMID:24819046
After the feature presentation: technologies bridging untargeted metabolomics and biology. PMID:24816495
Biomarkers in Alzheimer's disease analysis by mass spectrometry-based proteomics. PMID:24806343
Integrating omics technologies to study pulmonary physiology and pathology at the systems level. PMID:24802001
Exo-metabolome of Pseudovibrio sp. FO-BEG1 analyzed by ultra-high resolution mass spectrometry and the effect of phosphate limitation. PMID:24787987
Customized metabolomics database for the analysis of NMR ¹H-¹H TOCSY and ¹³C-¹H HSQC-TOCSY spectra of complex mixtures. PMID:24773139
Changes in metabolite profiles caused by genetically determined obesity in mice. PMID:24772056
Metabolomics in nutritional epidemiology: identifying metabolites associated with diet and quantifying their potential to uncover diet-disease relations in populations. PMID:24740205
Multi-TGDR, a multi-class regularization method, identifies the metabolic profiles of hepatocellular carcinoma and cirrhosis infected with hepatitis B or hepatitis C virus. PMID:24707821
Influence of iron and aeration on Staphylococcus aureus growth, metabolism, and transcription. PMID:24706736
Metabolomics network characterization of resuscitation after normocapnic hypoxia in a newborn piglet model supports the hypothesis that room air is better. PMID:24696864
Integrated LC-MS/MS system for plant metabolomics. PMID:24688692
Statistical methods for the analysis of high-throughput metabolomics data. PMID:24688690
A rough guide to metabolite identification using high resolution liquid chromatography mass spectrometry in metabolomic profiling in metazoans. PMID:24688687
Identification of metabolites from liquid chromatography-coulometric array detection profiling: gas chromatography-mass spectrometry and refractionation provide essential information orthogonal to LC-MS/microNMR. PMID:24657819
An R package to analyse LC/MS metabolomic data: MAIT (Metabolite Automatic Identification Toolkit). PMID:24642061
A pilot study exploring the use of breath analysis to differentiate healthy cattle from cattle experimentally infected with Mycobacterium bovis. PMID:24586655
Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization. PMID:24559180
A metabolic biosignature of early response to anti-tuberculosis treatment. PMID:24484441
Metabolomics reveals a role for the chromatin-binding protein HMGN5 in glutathione metabolism. PMID:24392144
The 1H NMR profile of healthy dog cerebrospinal fluid. PMID:24376499
A relationship between Pseudomonal growth behaviour and cystic fibrosis patient lung function identified in a metabolomic investigation. PMID:24367285
What Is the Opposite of Pandora's Box? Direct Analysis, Ambient Ionization, and a New Generation of Atmospheric Pressure Ion Sources. PMID:24349926
Dithranol as a matrix for matrix assisted laser desorption/ionization imaging on a fourier transform ion cyclotron resonance mass spectrometer. PMID:24300588
The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. PMID:24234439
Glutamine/glutamate metabolism studied with magnetic resonance spectroscopic imaging for the characterization of adrenal nodules and masses. PMID:24199200
Multidimensional approaches to NMR-based metabolomics. PMID:24195689
Catabolite control protein E (CcpE) is a LysR-type transcriptional regulator of tricarboxylic acid cycle activity in Staphylococcus aureus. PMID:24194525
Two birds with one stone: doing metabolomics with your proteomics kit. PMID:24155035
SIDD: a semantically integrated database towards a global view of human disease. PMID:24146757
Detection of an extended human volatome with comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry. PMID:24086492
Doping control using high and ultra-high resolution mass spectrometry based non-targeted metabolomics-a case study of salbutamol and budesonide abuse. PMID:24058591
Postgenomics diagnostics: metabolomics approaches to human blood profiling. PMID:24044364
The human urine metabolome. PMID:24023812
Analyzing LC/MS metabolic profiling data in the context of existing metabolic networks. PMID:24010053
Metabolomics in the diagnosis of acute myocardial ischemia. PMID:23990264
Optimized metabolomic approach to identify uremic solutes in plasma of stage 3-4 chronic kidney disease patients. PMID:23936492
Investigation of endogenous compounds for assessing the drug interactions in the urinary excretion involving multidrug and toxin extrusion proteins. PMID:23907530
An integrated clinico-metabolomic model improves prediction of death in sepsis. PMID:23884467
Predicting network activity from high throughput metabolomics. PMID:23861661
An untargeted metabolomic workflow to improve structural characterization of metabolites. PMID:23829391
Recent advances in the application of metabolomics to Alzheimer's Disease. PMID:23816564
Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity. PMID:23775562
INMEX--a web-based tool for integrative meta-analysis of expression data. PMID:23766290
Small-volume analysis of cell-cell signaling molecules in the brain. PMID:23748227
The human ΔNp53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function. PMID:23734707
HR-MAS NMR tissue metabolomic signatures cross-validated by mass spectrometry distinguish bladder cancer from benign disease. PMID:23731241
High-resolution quantitative metabolome analysis of urine by automated flow injection NMR. PMID:23718684
Untargeted metabolomics from biological sources using ultraperformance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS). PMID:23711563
Nuclear magnetic resonance based profiling of biofluids reveals metabolic dysregulation in HIV-infected persons and those on anti-retroviral therapy. PMID:23696880
A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL. PMID:23670529
Metabolomic profiling of urine: response to a randomised, controlled feeding study of select fruits and vegetables, and application to an observational study. PMID:23657156
Qualitative Characterization of the Rat Liver Mitochondrial Lipidome using LC-MS Profiling and High Energy Collisional Dissociation (HCD) All Ion Fragmentation. PMID:23646040
Numerous protein-bound solutes are cleared by the kidney with high efficiency. PMID:23636170
Inactivation of the Pta-AckA pathway causes cell death in Staphylococcus aureus. PMID:23625849
Identification of plasma metabolomic profiling for diagnosis of esophageal squamous-cell carcinoma using an UPLC/TOF/MS platform. PMID:23615477
NGAL and metabolomics: the single biomarker to reveal the metabolome alterations in kidney injury. PMID:23607092
Global mass spectrometry based metabolomics profiling of erythrocytes infected with Plasmodium falciparum. PMID:23593322
Pharmacometabolomic approach to predict QT prolongation in guinea pigs. PMID:23593245
Recent progress in the development of metabolome databases for plant systems biology. PMID:23577015
Metabolite profiling to characterize disease-related bacteria: gluconate excretion by Pseudomonas aeruginosa mutants and clinical isolates from cystic fibrosis patients. PMID:23572517
Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei. PMID:23571546
Bioanalysis of eukaryotic organelles. PMID:23570618
A novel l-isoleucine-4'-dioxygenase and l-isoleucine dihydroxylation cascade in Pantoea ananatis. PMID:23554367
Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry. PMID:23538882
Integration of clinical data with a genome-scale metabolic model of the human adipocyte. PMID:23511207
Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study. PMID:23497222
Subpathway-GM: identification of metabolic subpathways via joint power of interesting genes and metabolites and their topologies within pathways. PMID:23482392
Urinary 1H-NMR metabolomics can distinguish pancreatitis patients from healthy controls. PMID:23474563
Metabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality. PMID:23471468
NMR spectroscopy of macrophages loaded with native, oxidized or enzymatically degraded lipoproteins. PMID:23457556
A community-driven global reconstruction of human metabolism. PMID:23455439
Computational mass spectrometry for small molecules. PMID:23453222
Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma. PMID:23414815
A detailed physiologically based model to simulate the pharmacokinetics and hormonal pharmacodynamics of enalapril on the circulating endocrine Renin-Angiotensin-aldosterone system. PMID:23404365
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. PMID:23384594
Potential of urinary metabolites for diagnosing multiple sclerosis. PMID:23369377
Hybrid feature detection and information accumulation using high-resolution LC-MS metabolomics data. PMID:23362826
Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals. PMID:23360422
Proteomics and metabolomics in renal transplantation-quo vadis? PMID:23350848
BioSM: metabolomics tool for identifying endogenous mammalian biochemical structures in chemical structure space. PMID:23330685
Pre-, pro-, and synbiotics: do they have a role in reducing uremic toxins? A systematic review and meta-analysis. PMID:23316359
Prioritization of putative metabolite identifications in LC-MS/MS experiments using a computational pipeline. PMID:23307777
Automated method for analysis of tryptophan and tyrosine metabolites using capillary electrophoresis with native fluorescence detection. PMID:23307134
Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury. PMID:23303944
Chapter 3: Small molecules and disease. PMID:23300405
Metabolic changes in urine during and after pregnancy in a large, multiethnic population-based cohort study of gestational diabetes. PMID:23285025
Nuclear reprogramming with c-Myc potentiates glycolytic capacity of derived induced pluripotent stem cells. PMID:23247633
Urinary metabolomic signature of esophageal cancer and Barrett's esophagus. PMID:23241138
Consistency of systematic chemical identifiers within and between small-molecule databases. PMID:23237381
MetaboID: a graphical user interface package for assignment of 1H NMR spectra of bodyfluids and tissues. PMID:23232331
Global metabolic profiling of animal and human tissues via UPLC-MS. PMID:23222455
Method development for fecal lipidomics profiling. PMID:23210743
CcpA regulates arginine biosynthesis in Staphylococcus aureus through repression of proline catabolism. PMID:23209408
A mass spectrometric study for comparative analysis and evaluation of metabolite recovery from plasma by various solvent systems. PMID:23204928
Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin. PMID:23185347
The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013. PMID:23180789
Metabolomics profiling of extracellular metabolites in CHO-K1 cells cultured in different types of growth media. PMID:23179090
A metabolic model for members of the genus Tetrasphaera involved in enhanced biological phosphorus removal. PMID:23178666
Somatic transposition in the brain has the potential to influence the biosynthesis of metabolites involved in Parkinson's disease and schizophrenia. PMID:23176288
Biomarkers of whale shark health: a metabolomic approach. PMID:23166652
mzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data. PMID:23162054
HMDB 3.0--The Human Metabolome Database in 2013. PMID:23161693
Development of isotope labeling LC-MS for human salivary metabolomics and application to profiling metabolome changes associated with mild cognitive impairment. PMID:23150892
Integrating cellular metabolism into a multiscale whole-body model. PMID:23133351
ECMDB: the E. coli Metabolome Database. PMID:23109553
Structural characterization of plasma metabolites detected via LC-electrochemical coulometric array using LC-UV fractionation, MS, and NMR. PMID:23106399
Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information. PMID:23093944
IUPHAR-DB: updated database content and new features. PMID:23087376
High-resolution homonuclear 2D NMR of carbon-13 enriched metabolites and their mixtures. PMID:23079590
A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis. PMID:23042035
Genetic variation in metabolic phenotypes: study designs and applications. PMID:23032255
Profiling the anaerobic response of C. elegans using GC-MS. PMID:23029411
Systems-level characterization of a host-microbe metabolic symbiosis in the mammalian gut. PMID:23022739
Exploring chemical space for drug discovery using the chemical universe database. PMID:23019491
TOCCATA: a customized carbon total correlation spectroscopy NMR metabolomics database. PMID:23016498
Novel biomarkers for pre-diabetes identified by metabolomics. PMID:23010998
OMG: Open Molecule Generator. PMID:22985496
Online tools for bioinformatics analyses in nutrition sciences. PMID:22983844
Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiency. PMID:22972948
An accelerated workflow for untargeted metabolomics using the METLIN database. PMID:22965049
Understanding Dupuytren's Disease Using Systems Biology: A Move Away from Reductionism. PMID:22934066
CardioNet: a human metabolic network suited for the study of cardiomyocyte metabolism. PMID:22929619
Schizophrenia shows a unique metabolomics signature in plasma. PMID:22892715
Phenol-Explorer 2.0: a major update of the Phenol-Explorer database integrating data on polyphenol metabolism and pharmacokinetics in humans and experimental animals. PMID:22879444
Preclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders. PMID:22877223
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer. PMID:22869720
Mapping between databases of compounds and protein targets. PMID:22821596
MassTRIX reloaded: combined analysis and visualization of transcriptome and metabolome data. PMID:22815716
Analysis of bacterial biofilms using NMR-based metabolomics. PMID:22800371
Quantitative assignment of reaction directionality in a multicompartmental human metabolic reconstruction. PMID:22768925
MetaboSearch: tool for mass-based metabolite identification using multiple databases. PMID:22768229
Ion annotation-assisted analysis of LC-MS based metabolomic experiment. PMID:22759585
Genes2FANs: connecting genes through functional association networks. PMID:22748121
In vitro microbiotic fermentation causes an extensive metabolite turnover of rye bran phytochemicals. PMID:22745732
NetWalker: a contextual network analysis tool for functional genomics. PMID:22732065
Mass spectrometry-based metabolomics to elucidate functions in marine organisms and ecosystems. PMID:22690147
Homeostatic imbalance and colon cancer: the dynamic epigenetic interplay of inflammation, environmental toxins, and chemopreventive plant compounds. PMID:22675672
Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression. PMID:22628619
Natural product-likeness score revisited: an open-source, open-data implementation. PMID:22607271
ZINC: a free tool to discover chemistry for biology. PMID:22587354
Serum metabolomic profile as a means to distinguish stage of colorectal cancer. PMID:22583555
MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis. PMID:22553367
MarVis-Filter: ranking, filtering, adduct and isotope correction of mass spectrometry data. PMID:22550397
Multi-platform characterization of the human cerebrospinal fluid metabolome: a comprehensive and quantitative update. PMID:22546835
Genome-wide association studies with metabolomics. PMID:22546499
Nutritional metabolomics: progress in addressing complexity in diet and health. PMID:22540256
Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers. PMID:22537153
1H NMR metabolomics analysis of glioblastoma subtypes: correlation between metabolomics and gene expression characteristics. PMID:22528487
Metab2MeSH: annotating compounds with medical subject headings. PMID:22492643
Innovation: Metabolomics: the apogee of the omics trilogy. PMID:22436749
NMR metabolomics of MTLn3E breast cancer cells identifies a role for CXCR4 in lipid and choline regulation. PMID:22432781
Microbial metabolomics. PMID:22379393
Revisiting the reactivity of uracil during collision induced dissociation: tautomerism and charge-directed processes. PMID:22351291
Metabolite identification and quantitation in LC-MS/MS-based metabolomics. PMID:22345829
Targeted metabolic imaging to improve the management of heart disease. PMID:22340831
In-silico studies in Chinese herbal medicines' research: evaluation of in-silico methodologies and phytochemical data sources, and a review of research to date. PMID:22326356
Recent advances of metabolomics in plant biotechnology. PMID:22308170
Nutrigenetics, nutrigenomics, and selenium. PMID:22303312
Surrogate genetics and metabolic profiling for characterization of human disease alleles. PMID:22267502
Implication for functions of the ectopic adipocyte copper amine oxidase (AOC3) from purified enzyme and cell-based kinetic studies. PMID:22238597
Dynamic phosphometabolomic profiling of human tissues and transgenic models by 18O-assisted ³¹P NMR and mass spectrometry. PMID:22234996
Modeling community-wide molecular networks of multicellular systems. PMID:22210865
Understanding and classifying metabolite space and metabolite-likeness. PMID:22194963
A HNMR-based metabonomics study of postmenopausal osteoporosis and intervention effects of Er-Xian Decoction in ovariectomized rats. PMID:22174622
In-silico human genomics with GeneCards. PMID:22155609
MMMDB: Mouse Multiple Tissue Metabolome Database. PMID:22139941
The human plasma lipidome. PMID:22070478
H NMR spectroscopy-based metabolomic assessment of uremic toxicity, with toxicological outcomes, in male rats following an acute, mid-life insult from ochratoxin a. PMID:22069722
YMDB: the Yeast Metabolome Database. PMID:22064855
Metabonomics-based omics study and atherosclerosis. PMID:22040517
Predicting the in vivo mechanism of action for drug leads using NMR metabolomics. PMID:22007661
MetaboHunter: an automatic approach for identification of metabolites from 1H-NMR spectra of complex mixtures. PMID:21999117
A metabolomic approach for diagnosis of experimental sepsis. PMID:21976186
Influence of common preanalytical variations on the metabolic profile of serum samples in biobanks. PMID:21964699
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. PMID:21963238
Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives. PMID:21949491
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PMID:21931564
Metabolomics as a tool for cardiac research. PMID:21931361
MetaboLab--advanced NMR data processing and analysis for metabolomics. PMID:21914187
NMR in metabolomics and natural products research: two sides of the same coin. PMID:21888316
Human metabolic profiles are stably controlled by genetic and environmental variation. PMID:21878913
Approaches for the study of cancer: towards the integration of genomics, proteomics and metabolomics. PMID:21865133
Structural diversity of biologically interesting datasets: a scaffold analysis approach. PMID:21824432
Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injury. PMID:21823223
Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. PMID:21803296
Colonic contribution to uremic solutes. PMID:21784895
Serum lipidomics profiling using LC-MS and high-energy collisional dissociation fragmentation: focus on triglyceride detection and characterization. PMID:21774539
Metabolomics reveals phospholipids as important nutrient sources during Salmonella growth in bile in vitro and in vivo. PMID:21764918
iAB-RBC-283: A proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states. PMID:21749716
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. PMID:21720319
Software and resources for computational medicinal chemistry. PMID:21707404
Radiation metabolomics and its potential in biodosimetry. PMID:21692691
NMR analysis of a stress response metabolic signaling network. PMID:21692534
Mining metabolites: extracting the yeast metabolome from the literature. PMID:21687783
Profiles of Microbial Fatty Acids in the Human Metabolome are Disease-Specific. PMID:21687748
The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses. PMID:21680948
MeRy-B: a web knowledgebase for the storage, visualization, analysis and annotation of plant NMR metabolomic profiles. PMID:21668943
Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst. PMID:21637195
Extending biochemical databases by metabolomic surveys. PMID:21566124
Virtual Screening with AutoDock: Theory and Practice. PMID:21532931
A survey of metabolic databases emphasizing the MetaCyc family. PMID:21523460
Qualitative metabolome analysis of human cerebrospinal fluid by 13C-/12C-isotope dansylation labeling combined with liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. PMID:21472593
Lipidomics at the interface of structure and function in systems biology. PMID:21439472
Role of aminotransferases in glutamate metabolism of human erythrocytes. PMID:21380856
The human serum metabolome. PMID:21359215
Use of in vivo two-dimensional MR spectroscopy to compare the biochemistry of the human brain to that of glioblastoma. PMID:21357517
On the future of "omics": lipidomics. PMID:21318352
Advances in structure elucidation of small molecules using mass spectrometry. PMID:21289855
Deciphering squamous cell carcinoma using multidimensional genomic approaches. PMID:21234096
Lipidomics profiling by high-resolution LC-MS and high-energy collisional dissociation fragmentation: focus on characterization of mitochondrial cardiolipins and monolysocardiolipins. PMID:21192696
MIPS: curated databases and comprehensive secondary data resources in 2010. PMID:21109531
DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. PMID:21059682
Analytical approaches to metabolomics and applications to systems biology. PMID:21044761
A network perspective on metabolism and aging. PMID:21031036
Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research. PMID:20980656
A method for comprehensive analysis of urinary acylglycines by using ultra-performance liquid chromatography quadrupole linear ion trap mass spectrometry. PMID:20971021
metaP-server: a web-based metabolomics data analysis tool. PMID:20936179
Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. PMID:20936122
Metabolic consequences of sepsis-induced acute lung injury revealed by plasma ¹H-nuclear magnetic resonance quantitative metabolomics and computational analysis. PMID:20889676
Comparative genomic analysis of pathogenic and probiotic Enterococcus faecalis isolates, and their transcriptional responses to growth in human urine. PMID:20824220
Molecular diagnostics in transplantation. PMID:20736923
Tracer-based metabolomics: concepts and practices. PMID:20713038
Activity-based protein profiling for biochemical pathway discovery in cancer. PMID:20703252
NMR metabolomic profiling reveals new roles of SUMOylation in DNA damage response. PMID:20695451
GPCRs, G-proteins, effectors and their interactions: human-gpDB, a database employing visualization tools and data integration techniques. PMID:20689020
MZmine 2: modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data. PMID:20650010
Elevated CSF N-acetylaspartylglutamate suggests specific molecular diagnostic abnormalities in patients with white matter diseases. PMID:20637281
The MetabolomeExpress Project: enabling web-based processing, analysis and transparent dissemination of GC/MS metabolomics datasets. PMID:20626915
So what have data standards ever done for us? The view from metabolomics. PMID:20587079
Biophysical characterization of recombinant proteins: a key to higher structural genomics success. PMID:20466062
Global metabolic profiling procedures for urine using UPLC-MS. PMID:20448546
MetExplore: a web server to link metabolomic experiments and genome-scale metabolic networks. PMID:20444866
Quantitative global studies of reactomes and metabolomes using a vectorial representation of reactions and chemical compounds. PMID:20406431
Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. PMID:20349993
Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers. PMID:20331867
Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining. PMID:20331846
Xenobiotic metabolism: a view through the metabolometer. PMID:20232918
13C-formylation for improved nuclear magnetic resonance profiling of amino metabolites in biofluids. PMID:20180538
Lists2Networks: integrated analysis of gene/protein lists. PMID:20152038
Metscape: a Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks. PMID:20139469
T3DB: a comprehensively annotated database of common toxins and their targets. PMID:19897546
The role of mass spectrometry-based metabolomics in medical countermeasures against radiation. PMID:19890938
Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour 'rules'. PMID:19622150
Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. PMID:19618939
Database resources in metabolomics: an overview. PMID:19418229
Metabolomics: moving to the clinic. PMID:19399626
Metabolomics: the principles and potential applications to transplantation PubMed citations: 38.

38 articles citing: Metabolomics: the principles and potential applications to transplantation

Quantitative Metabolomics of Tissue, Perfusate, and Bile from Rat Livers Subjected to Normothermic Machine Perfusion. PMID:35327340
A Versatile Multichannel Instrument for Measurement of Ratiometric Fluorescence Intensity and Phosphorescence Lifetime. PMID:34858770
An emerging potential of metabolomics in multiple sclerosis: a comprehensive overview. PMID:33449145
The Role of Metabolomics in Current Concepts of Organ Preservation. PMID:32927605
Nuclear Magnetic Resonance to Detect Rumen Metabolites Associated with Enteric Methane Emissions from Beef Cattle. PMID:32221381
Hyper response to ovarian stimulation affects the follicular fluid metabolomic profile of women undergoing IVF similarly to polycystic ovary syndrome. PMID:30830356
Metabolomics Approaches for the Diagnosis and Understanding of Kidney Diseases. PMID:30769897
The role of the Human Metabolome Database in inborn errors of metabolism. PMID:29663269
Gas Chromatography-Mass Spectrometry for Metabolite Profiling of Japanese Black Cattle Naturally Contaminated with Zearalenone and Sterigmatocystin. PMID:28934162
Navigating T-Cell Immunometabolism in Transplantation. PMID:28930796
A Metabolomics Signature Linked To Liver Fibrosis In The Serum Of Transplanted Hepatitis C Patients. PMID:28874799
Gestational Diabetes Mellitus and Metabolic Disorder Among the Different Phenotypes of Polycystic Ovary Syndrome. PMID:28584602
NMR-based Stable Isotope Resolved Metabolomics in systems biochemistry. PMID:28263717
Mass Spectrometry Based Metabolomics Comparison of Liver Grafts from Donors after Circulatory Death (DCD) and Donors after Brain Death (DBD) Used in Human Orthotopic Liver Transplantation. PMID:27835640
A Metabolomic Approach (1H HRMAS NMR Spectroscopy) Supported by Histology to Study Early Post-transplantation Responses in Islet-transplanted Livers. PMID:27766032
Metabolomics and Its Application to Acute Lung Diseases. PMID:26973643
Management of immunosuppressant agents following liver transplantation: Less is more. PMID:26839639
Lipidomics comparing DCD and DBD liver allografts uncovers lysophospholipids elevated in recipients undergoing early allograft dysfunction. PMID:26635289
Biomarkers in Transplantation--Proteomics and Metabolomics. PMID:26418702
A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine. PMID:25871999
Metabolite Profiling in the Pursuit of Biomarkers for IVF Outcome: The Case for Metabolomics Studies. PMID:25763388
Low invasive in vivo tissue sampling for monitoring biomarkers and drugs during surgery. PMID:24687119
Proteomics and metabolomics in renal transplantation-quo vadis? PMID:23350848
Metabolic profiles characterizing different phenotypes of polycystic ovary syndrome: plasma metabolomics analysis. PMID:23198915
Gas chromatography-mass spectrometry for metabolite profiling of Japanese medaka (Oryzias latipes) juveniles exposed to malathion. PMID:22828887
Viral infection in renal transplant recipients. PMID:22654630
Marking renal injury: can we move beyond serum creatinine? PMID:22424431
Biomarkers of acute kidney injury. PMID:22131986
Metabolomics in the study of kidney diseases. PMID:22025087
EPA or DHA supplementation increases triacylglycerol, but not phospholipid, levels in isolated rat cardiomyocytes. PMID:21544603
Biomarkers of immunosuppressant organ toxicity after transplantation: status, concepts and misconceptions. PMID:21241200
Analytical approaches to metabolomics and applications to systems biology. PMID:21044761
Differentiation of alloreactive versus CD3/CD28 stimulated T-lymphocytes using Raman spectroscopy: a greater specificity for noninvasive acute renal allograft rejection detection. PMID:19753631
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function. PMID:19099400
Raman spectroscopic differentiation of activated versus non-activated T lymphocytes: an in vitro study of an acute allograft rejection model. PMID:18996128
Metabolomics-based methods for early disease diagnostics. PMID:18785810
Noninvasive prediction of organ graft rejection and outcome using gene expression patterns. PMID:18645476
Early detection of graft failure using the blood metabolic profile of a liver recipient. PMID:17318087
http://dx.doi.org/10.1093/nar/gks1065

Tags:

Tags
More detailed information about this field from each metasource.

chemical entity
metasource: Fairsharing.org
version: FAIRsharing.org: HMDB; The Human Metabolome Database; DOI: https://doi.org/10.25504/FAIRsharing.sye5js; Last edited: April 26, 2021, 3:27 p.m.; Last accessed: Jan 03 2022 7:08 p.m.

metabolite
metasource: Fairsharing.org
version: FAIRsharing.org: HMDB; The Human Metabolome Database; DOI: https://doi.org/10.25504/FAIRsharing.sye5js; Last edited: April 26, 2021, 3:27 p.m.; Last accessed: Jan 03 2022 7:08 p.m.

metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

small molecule
metasource: Fairsharing.org
version: FAIRsharing.org: HMDB; The Human Metabolome Database; DOI: https://doi.org/10.25504/FAIRsharing.sye5js; Last edited: April 26, 2021, 3:27 p.m.; Last accessed: Jan 03 2022 7:08 p.m.

metabolic and signaling pathways
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

metabolic pathways
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

fair
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

biomarker discovery
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

clinical chemistry
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

diseases
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

enzyme
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

general education
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

life sciences
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

metabolomics
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

pathways
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

proteins
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

reactions
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

transporter
metasource: re3data.org
version: re3data.org: Human Metabolome Database; editing status 2022-06-14; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R33K90 last accessed: 2022-11-04

small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

surgery
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

nmr
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

model organisms
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:47.412261

chemical entity metabolite small molecule metabolic and signaling pathways metabolic and signaling pathways biomarker discovery clinical chemistry diseases enzyme general education life sciences metabolomics pathways proteins reactions transporter small molecule surgery nmr model organisms

More to explore:

1/20

Previous Next

Need help integrating and/or managing biomedical data?

Webpage:

Licence:

More to explore:

1/20

The Yeast Metabolome DataBase

ECMDB

Golm Metabolome Database

Small Molecule Pathway Database

M-IOLITE

MMCD

PAMDB

PathBank

Human Protein Atlas

Metabolomics Workbench

MMHub

Ligand Expo

MMMDB

Human Protein Reference Database

Human Endogenous Retrovirus database

The Human OligoGenome Resource: A Database for Customized Targeted Resequencing Covering the Human Genome

Human Phenotype Ontology

Human Mitochondrial Database

MetaCyc

InterFil