SuperCYP

Names
More detailed information about this field from each metasource.

SuperCYP
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

supercyp
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

Other names: supercyp

This source may no longer be available. No known URL could be resolved successfully.

Cytochrome P450 alleles and drug interactions

Webpage:

http://bioinformatics.charite.de/supercyp

Publications:

Publications
More detailed information about this field from each metasource.

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions
PMID: 19934256
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

http://nar.oxfordjournals.org/content/38/suppl_1/D237
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions PubMed citations: 90.

90 articles citing: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions

Comparison of Computerized Prescription Support Systems in COVID-19 Patients: INTERCheck and Drug-PIN. PMID:34977463
MetaClass, a Comprehensive Classification System for Predicting the Occurrence of Metabolic Reactions Based on the MetaQSAR Database. PMID:34641400
Applying Next-Generation Sequencing Platforms for Pharmacogenomic Testing in Clinical Practice. PMID:34512329
Biomolecule and Bioentity Interaction Databases in Systems Biology: A Comprehensive Review. PMID:34439912
Primary Thromboprophylaxis in Patients with Malignancies: Daily Practice Recommendations by the Hemostasis Working Party of the German Society of Hematology and Medical Oncology (DGHO), the Society of Thrombosis and Hemostasis Research (GTH), and the Austrian Society of Hematology and Oncology (ÖGHO). PMID:34200741
Psychoactive Medication, Violence, and Variant Alleles for Cytochrome P450 Genes. PMID:34069803
Contributions of synaptic and astrocyte physiology to the anaesthetised encephalogram revealed using a computational model. PMID:33773753
Advancement in predicting interactions between drugs used to treat psoriasis and its comorbidities by integrating molecular and clinical resources. PMID:33544847
A computational approach to predict multi-pathway drug-drug interactions: A case study of irinotecan, a colon cancer medication. PMID:33424244
Inhibition and induction of CYP enzymes in humans: an update. PMID:33111191
Genotype of Null Polymorphisms in Genes GSTM1, GSTT1, CYP1A1, and CYP1A1*2A (rs4646903 T>C)/CYP1A1*2C (rs1048943 A>G) in Patients with Larynx Cancer in Southeast Spain. PMID:32882964
Drug-Drug Interactions of 257 Antineoplastic and Supportive Care Agents With 7 Anticoagulants: A Comprehensive Review of Interactions and Mechanisms. PMID:32862668
Structural Perspectives of the CYP3A Family and Their Small Molecule Modulators in Drug Metabolism. PMID:32789028
Discovery and modification of cytochrome P450 for plant natural products biosynthesis. PMID:32637672
Norditerpenoids with Selective Anti-Cholinesterase Activity from the Roots of Perovskia atriplicifolia Benth. PMID:32586060
PTH suppression by calcitriol does not predict off-target actions in experimental CKD. PMID:32519465
Determination of parecoxib and valdecoxib in rat plasma by UPLC-MS/MS and its application to pharmacokinetics studies. PMID:32264977
SuperCYPsPred-a web server for the prediction of cytochrome activity. PMID:32182358
Expanding the Diversity of Plant Monoterpenoid Indole Alkaloids Employing Human Cytochrome P450 3A4. PMID:32181956
Functional characterization of cytochrome P450 CYP81A subfamily to disclose the pattern of cross-resistance in Echinochloa phyllopogon. PMID:31898147
Highlights in Resistance Mechanism Pathways for Combination Therapy. PMID:31480389
Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S-Transferases. PMID:31457004
A Pilot Study towards the Impact of Type 2 Diabetes on the Expression and Activities of Drug Metabolizing Enzymes and Transporters in Human Duodenum. PMID:31269743
Mifepristone: An Uncommon Cause of Drug-Induced Liver Injury. PMID:31236162
Active repurposing of drug candidates for melanoma based on GWAS, PheWAS and a wide range of omics data. PMID:31221082
The Cancer Drug Fraction of Metabolism Database. PMID:31206254
Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study. PMID:31158489
Herb-drug interactions: a novel algorithm-assisted information system for pharmacokinetic drug interactions with herbal supplements in cancer treatment. PMID:31154477
Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids in vitro. PMID:31091988
Prospects for repurposing CNS drugs for cancer treatment. PMID:31044029
Nanocrystalization: An Emerging Technology to Enhance the Bioavailability of Poorly Soluble Drugs. PMID:30961518
Insight of Captagon Abuse by Chemogenomics Knowledgebase-guided Systems Pharmacology Target Mapping Analyses. PMID:30783122
BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification. PMID:30612223
Pharmacokinetic Interactions of Clinical Interest Between Direct Oral Anticoagulants and Antiepileptic Drugs. PMID:30581412
CYP2D6 genotypes in revolving door patients with bipolar disorders: A case series. PMID:30212929
Computational resources associating diseases with genotypes, phenotypes and exposures. PMID:30102366
Application of pharmacogenetics in clinical practice: problems and solutions. PMID:29922908
Pharmacogenomic Approaches for Automated Medication Risk Assessment in People with Polypharmacy. PMID:29888060
Murburn Concept: A Molecular Explanation for Hormetic and Idiosyncratic Dose Responses. PMID:29770107
Screening for Biologically Annotated Drugs That Trigger Triacylglycerol Accumulation in the Diatom Phaeodactylum. PMID:29535162
Perspective on the Genetic Response to Antiparasitics: A Review Article. PMID:29317871
Targeting DNA Repair through Podophyllotoxin and Rutin Formulation in Hematopoietic Radioprotection: An in Silico, in Vitro, and in Vivo Study. PMID:29163150
The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p. PMID:28822783
The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models. PMID:28781990
Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. PMID:28774812
Ivermectin to reduce malaria transmission II. Considerations regarding clinical development pathway. PMID:28434405
Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety. PMID:28434401
Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing. PMID:28044414
Drug-drug interaction discovery and demystification using Semantic Web technologies. PMID:28031284
Pharmacogenomics of second-line drugs used for treatment of unresponsive or relapsed osteosarcoma patients. PMID:27883291
A service improvement project to review prescribing information provided by general practitioners for new referrals to a UK National Health Service hospital pain clinic: potential implications of CYP2D6 enzyme inhibition. PMID:27867512
Xenobiotic metabolism in differentiated human bronchial epithelial cells. PMID:27738743
XMetDB: an open access database for xenobiotic metabolism. PMID:27651835
Associations between CYP1A1 rs1048943 A > G and rs4646903 T > C genetic variations and colorectal cancer risk: Proof from 26 case-control studies. PMID:27384991
Effects of traditional herbal formulae on human CYP450 isozymes. PMID:27352178
Immunohistochemical markers of CYP3A4 and CYP3A7: a new tool towards personalized pharmacotherapy of hepatocellular carcinoma. PMID:27349315
Role of Pharmacogenetics in Improving the Safety of Psychiatric Care by Predicting the Potential Risks of Mania in CYP2D6 Poor Metabolizers Diagnosed With Bipolar Disorder. PMID:26871771
Trimester-Specific Population Pharmacokinetics and Other Correlates of Variability in Sulphadoxine-Pyrimethamine Disposition Among Ugandan Pregnant Women. PMID:26586482
PDID: database of molecular-level putative protein-drug interactions in the structural human proteome. PMID:26504143
Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning. PMID:26372358
A Combined Molecular Docking/Dynamics Approach to Probe the Binding Mode of Cancer Drugs with Cytochrome P450 3A4. PMID:26287147
A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case. PMID:26100720
Predicting drug metabolism: experiment and/or computation? PMID:25907346
PubChem applications in drug discovery: a bibliometric analysis. PMID:25168772
MutaCYP: Classification of missense mutations in human cytochromes P450. PMID:25073475
Predicting drug metabolism by CYP1A1, CYP1A2, and CYP1B1: insights from MetaSite, molecular docking and quantum chemical calculations. PMID:25028215
Strategies to overcome antileishmanial drugs unresponsiveness. PMID:24876851
Towards structural systems pharmacology to study complex diseases and personalized medicine. PMID:24830652
Different frequencies of drug resistance mutations among HIV-1 subtypes circulating in China: a comprehensive study. PMID:24663120
Predictors of blood trihalomethane concentrations in NHANES 1999-2006. PMID:24647036
Machine learning-based prediction of drug-drug interactions by integrating drug phenotypic, therapeutic, chemical, and genomic properties. PMID:24644270
Pharmacokinetics of lacosamide and omeprazole coadministration in healthy volunteers: results from a phase I, randomized, crossover trial. PMID:24567279
Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy. PMID:24340040
The Transformer database: biotransformation of xenobiotics. PMID:24334957
Sucralose, a synthetic organochlorine sweetener: overview of biological issues. PMID:24219506
A therapeutic interaction between cimetidine and clozapine: case study and review of the literature. PMID:24167705
DGIdb: mining the druggable genome. PMID:24122041
Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin. PMID:24023924
Improving data and knowledge management to better integrate health care and research. PMID:23808970
Saint John's wort, an herbal inducer of the cytochrome P4503A4 isoform, may alleviate symptoms of Willis-Ekbom's disease. PMID:23778343
Informatics confronts drug-drug interactions. PMID:23414686
CYPSI: a structure-based interface for cytochrome P450s and ligands in Arabidopsis thaliana. PMID:23256889
INDI: a computational framework for inferring drug interactions and their associated recommendations. PMID:22806140
MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes. PMID:22730453
Bioinformatics and variability in drug response: a protein structural perspective. PMID:22552919
Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy predictions. PMID:22539082
RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes. PMID:22524152
SuperTarget goes quantitative: update on drug-target interactions. PMID:22067455
Association between CYP1A1 polymorphism and colorectal cancer risk: a meta-analysis. PMID:21710246
PROMISCUOUS: a database for network-based drug-repositioning. PMID:21071407
http://nar.oxfordjournals.org/content/38/suppl_1/D237

Tags:

Tags
More detailed information about this field from each metasource.

protein sequence databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

databases of individual protein families
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

drug metabolism
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

genetic variation
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

endocrinology and metabolism
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

molecular interactions, pathways and networks
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:33.505738

protein sequence protein family drug metabolism genetic variation endocrinology and metabolism molecular interactions, pathways and networks small molecule

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SuperTarget

PROMISCUOUS

Plant Cytochrome P450 Database

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SuperNatural

COVID-19 Drug Interactions

Transformer

VMH

Cancer Drug Interactions

SuperSite

Pharmacogenomics Knowledge Base

HEP Drug Interactions

DoBISCUIT

SelenoDB

Het-PDB Navi

SuperTCM

DroID - Drosophila Interactions Database

TRIP

DAnCER