BloodSpot
BloodSpot is a database of mRNA expression in healthy and malignant haematopoiesis and includes data from both humans and mice. The core function of BloodSpot is to provide an expression plot of genes in healthy and cancerous haematopoietic cells at specific differentiation stages. In addition to the default plot, that displays an integrated expression plot, two additional levels of visualization are available; an interactive tree showing the hierarchical relationship between the samples, and a Kaplan-Meier survival plot. Prior to BloodSpot, this service was provided by an earlier project, HemaExplorer, also by the same research group. HemaExplorer was updated to the BloodSpot platform, which all users are encouraged to use instead.
Description
More detailed information about this field from each metasource.
BloodSpot is a database of mRNA expression in healthy and malignant haematopoiesis and includes data from both humans and mice. The core function of BloodSpot is to provide an expression plot of genes in healthy and cancerous haematopoietic cells at specific differentiation stages. In addition to the default plot, that displays an integrated expression plot, two additional levels of visualization are available; an interactive tree showing the hierarchical relationship between the samples, and a Kaplan-Meier survival plot. Prior to BloodSpot, this service was provided by an earlier project, HemaExplorer, also by the same research group. HemaExplorer was updated to the BloodSpot platform, which all users are encouraged to use instead.
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
BloodSpot is a database that provides gene expression profiles of genes and gene signatures in healthy and malignant hematopoiesis and includes data from both humans and mice. In addition to the default plot, that displays an integrated expression plot, two additional levels of visualization are available; an interactive tree showing the hierarchical relationship between the samples, and a Kaplan-Meier survival plot. The database is sub-divided into several datasets that are accessible for browsing.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://www.bloodspot.euWebpage
More detailed information about this field from each metasource.
http://www.bloodspot.eu
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://servers.binf.ku.dk/bloodspot/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Publications:
Publications
More detailed information about this field from each metasource.
BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis
PMID: 26507857
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
PMID: 23143109
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis
PMID: 22745298
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkv1101
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis
PMID: 26507857
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
PMID: 23143109
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis
PMID: 22745298
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkv1101
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis
PubMed citations: 130.
130 articles citing: BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis
Bimodal expression of RHOH during myelomonocytic differentiation: Implications for the expansion of AML differentiation therapy. PMID:35845268
Protein Kinase C Epsilon Overexpression Is Associated With Poor Patient Outcomes in AML and Promotes Daunorubicin Resistance Through p-Glycoprotein-Mediated Drug Efflux. PMID:35707351
The BCAT1 CXXC Motif Provides Protection against ROS in Acute Myeloid Leukaemia Cells. PMID:35453368
Construction of a Pyroptosis-Related Signature for Prognostic Prediction and Characterization of Immune Microenvironment in Acute Myelogenous Leukemia. PMID:35308573
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia. PMID:35232995
CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells. PMID:35102167
HMCES safeguards genome integrity and long-term self-renewal of hematopoietic stem cells during stress responses. PMID:35039639
Tumor necrosis factor‑related apoptosis‑inducing ligand is a novel transcriptional target of runt‑related transcription factor 1. PMID:34958111
KDM4B promotes acute myeloid leukemia associated with AML1-ETO by regulating chromatin accessibility. PMID:34938963
MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis. PMID:34780648
NKL Homeobox Genes NKX2-3 and NKX2-4 Deregulate Megakaryocytic-Erythroid Cell Differentiation in AML. PMID:34768865
The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis. PMID:34740959
Glycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemia. PMID:34646384
Discovery of a Non-Nucleoside SETD2 Methyltransferase Inhibitor against Acute Myeloid Leukemia. PMID:34576219
Programmed necroptosis is upregulated in low-grade myelodysplastic syndromes and may play a role in the pathogenesis. PMID:34563605
The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation. PMID:34525179
CXCL15/Lungkine has suppressive activity on proliferation and expansion of multi-potential, erythroid, granulocyte and macrophage progenitors in S-phase specific manner. PMID:34520986
Novel Markers in Pediatric Acute Lymphoid Leukemia: The Role of ADAM6 in B Cell Leukemia. PMID:34249950
ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia. PMID:34081901
An integrated analysis of human myeloid cells identifies gaps in in vitro models of in vivo biology. PMID:33989517
Integrated OMICs unveil the bone-marrow microenvironment in human leukemia. PMID:33979628
BCOR gene alterations in hematologic diseases. PMID:33945606
CAR-T Cell Therapy for Acute Myeloid Leukemia: Preclinical Rationale, Current Clinical Progress, and Barriers to Success. PMID:33826079
High Expression of CLEC11A Predicts Favorable Prognosis in Acute Myeloid Leukemia. PMID:33747924
Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy. PMID:33742137
Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells. PMID:33659038
Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs. PMID:33564037
Low expression of ZHX1 and ZHX2 impacts on the prognosis of chronic lymphocytic leukemia. PMID:33541423
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer. PMID:33457104
Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation. PMID:33340029
SON inhibits megakaryocytic differentiation via repressing RUNX1 and the megakaryocytic gene expression program in acute megakaryoblastic leukemia. PMID:33247227
A new role of glutathione peroxidase 4 during human erythroblast enucleation. PMID:33211827
SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation. PMID:33054052
SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia. PMID:33037410
BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity. PMID:32954361
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML. PMID:32938585
Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches. PMID:32929022
A PML/RARα direct target atlas redefines transcriptional deregulation in acute promyelocytic leukemia. PMID:32854112
Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas. PMID:32703790
Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype. PMID:32678083
NRF2, a Transcription Factor for Stress Response and Beyond. PMID:32640524
Requirement for LIM kinases in acute myeloid leukemia. PMID:32591645
Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis. PMID:32564710
CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system. PMID:32411526
Characterizing the Role of SMYD2 in Mammalian Embryogenesis-Future Directions. PMID:32408548
Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy. PMID:32312983
The lysine methyltransferase SMYD2 is required for normal lymphocyte development and survival of hematopoietic leukemias. PMID:32115575
Activation of the Intracellular Pattern Recognition Receptor NOD2 Promotes Acute Myeloid Leukemia (AML) Cell Apoptosis and Provides a Survival Advantage in an Animal Model of AML. PMID:32094205
FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML. PMID:32066721
HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells. PMID:31890203
HBO1 is required for the maintenance of leukaemia stem cells. PMID:31827282
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus. PMID:31819086
The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling. PMID:31748347
Non-del(5q) myelodysplastic syndromes-associated loci detected by SNP-array genome-wide association meta-analysis. PMID:31738830
STAT5A and STAT5B-Twins with Different Personalities in Hematopoiesis and Leukemia. PMID:31690038
Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia. PMID:31611628
Epigenetic down-regulation of the HIST1 locus predicts better prognosis in acute myeloid leukemia with NPM1 mutation. PMID:31606046
Transferrin receptor 1-mediated iron uptake plays an essential role in hematopoiesis. PMID:31601687
Inflammation regulates long non-coding RNA-PTTG1-1:1 in myeloid leukemia. PMID:31582551
Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1). PMID:31576005
HLA class I-restricted T cell epitopes isolated and identified from myeloid leukemia cells. PMID:31575892
Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis. PMID:31142733
HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis. PMID:31033440
A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study. PMID:31015209
Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program. PMID:30917956
The Expression of the SLIT-ROBO Family in Adult Patients with Acute Myeloid Leukemia. PMID:30820596
Repository of Enriched Structures of Proteins Involved in the Red Blood Cell Environment (RESPIRE). PMID:30794542
Data mining for mutation-specific targets in acute myeloid leukemia. PMID:30728456
Selective targeting of NAMPT by KPT-9274 in acute myeloid leukemia. PMID:30692102
Off-target based drug repurposing opportunities for tivantinib in acute myeloid leukemia. PMID:30679640
Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9. PMID:30528456
A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. PMID:30503706
BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles. PMID:30395307
Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans. PMID:30395284
Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia. PMID:30381403
Chronic sympathetic driven hypertension promotes atherosclerosis by enhancing hematopoiesis. PMID:30361420
A Whole Methylome Study of Ethanol Exposure in Brain and Blood: An Exploration of the Utility of Peripheral Blood as Proxy Tissue for Brain in Alcohol Methylation Studies. PMID:30320886
SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness. PMID:30249787
Germline duplication of ATG2B and GSKIP genes is not required for the familial myeloid malignancy syndrome associated with the duplication of chromosome 14q32. PMID:30087419
A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. PMID:30082823
The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation. PMID:30046127
Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates. PMID:30015632
PI3K-Mediated Blimp-1 Activation Controls B Cell Selection and Homeostasis. PMID:29996100
DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia. PMID:29967349
Alas1 is essential for neutrophil maturation in zebrafish. PMID:29954941
AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells. PMID:29910151
MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. PMID:29777171
Survey and evaluation of mutations in the human KLF1 transcription unit. PMID:29700354
PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells. PMID:29641991
Repolarizing heterogeneous leukemia-associated macrophages with more M1 characteristics eliminates their pro-leukemic effects. PMID:29632729
The chromatin-remodeling factor CHD4 is required for maintenance of childhood acute myeloid leukemia. PMID:29599201
Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia. PMID:29594337
Single-cell qPCR facilitates the optimization of hematopoietic differentiation in hPSCs/OP9 coculture system. PMID:29561959
Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways. PMID:29555946
MLL2/KMT2D and MLL3/KMT2C expression correlates with disease progression and response to imatinib mesylate in chronic myeloid leukemia. PMID:29483845
Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma. PMID:29382756
Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome. PMID:29326122
Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL. PMID:29296813
A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2. PMID:29296759
Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor. PMID:29282252
ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia. PMID:29269781
Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair. PMID:29221109
StemMapper: a curated gene expression database for stem cell lineage analysis. PMID:29045725
The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. PMID:29021535
Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AML. PMID:29017060
Meis2 as a critical player in MN1-induced leukemia. PMID:28960191
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. PMID:28920958
Decitabine-Vorinostat combination treatment in acute myeloid leukemia activates pathways with potential for novel triple therapy. PMID:28881658
The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation. PMID:28778865
High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis. PMID:28720764
Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells. PMID:28714470
Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia. PMID:28703806
The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers. PMID:28574834
A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm. PMID:28550306
Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk. PMID:28549481
Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition. PMID:28481226
SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. PMID:28424516
Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia. PMID:28319094
High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells. PMID:28280275
RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemia. PMID:28107692
On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase. PMID:28025337
Biological Databases for Hematology Research. PMID:27965103
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. PMID:27956387
AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells. PMID:27713544
Novel function of FAXDC2 in megakaryopoiesis. PMID:27689744
Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals. PMID:27590115
Haemopedia: An Expression Atlas of Murine Hematopoietic Cells. PMID:27499199
The role of the CCN family of proteins in blood cancers. PMID:27485291
A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation. PMID:27365425
Protein Thiol Redox Signaling in Monocytes and Macrophages. PMID:27288099 -
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
PubMed citations: 46.
46 articles citing: HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Leukemic progenitor cells enable immunosuppression and post-chemotherapy relapse via IL-36-inflammatory monocyte axis. PMID:34623912
High Expression of CLEC11A Predicts Favorable Prognosis in Acute Myeloid Leukemia. PMID:33747924
USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells. PMID:33378683
Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation. PMID:33340029
KLF1/EKLF expression in acute leukemia is correlated with chromosomal abnormalities. PMID:32311573
Novel insights into the emerging roles of tRNA-derived fragments in mammalian development. PMID:32116113
Increased expression of interleukin-17 is associated with macrophages in chronic immune thrombocytopenia. PMID:31938354
Natural Killer Immunotherapy for Minimal Residual Disease Eradication Following Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia. PMID:31027331
Data mining for mutation-specific targets in acute myeloid leukemia. PMID:30728456
Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas. PMID:30683910
Classification of Widely and Rarely Expressed Genes with Recurrent Neural Network. PMID:30595815
BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles. PMID:30395307
CDK9 inhibitors in acute myeloid leukemia. PMID:29471852
Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation. PMID:28648895
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells. PMID:28436985
Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML. PMID:28122740
Biological Databases for Hematology Research. PMID:27965103
JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia. PMID:27840425
The role of the CCN family of proteins in blood cancers. PMID:27485291
Loss of Dnmt3b accelerates MLL-AF9 leukemia progression. PMID:27133822
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells. PMID:27121842
MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis. PMID:27018596
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia. PMID:26951332
The analysis of novel distal Cebpa enhancers and silencers using a transcriptional model reveals the complex regulatory logic of hematopoietic lineage specification. PMID:26945717
BCOR regulates myeloid cell proliferation and differentiation. PMID:26847029
Helicase-like transcription factor is a RUNX1 target whose downregulation promotes genomic instability and correlates with complex cytogenetic features in acute myeloid leukemia. PMID:26802049
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a. PMID:26728554
Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling. PMID:26716078
The multifaceted functions of C/EBPα in normal and malignant haematopoiesis. PMID:26601784
Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing. PMID:26575292
BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis. PMID:26507857
UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO. PMID:26449661
A ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway Compounds. PMID:26419938
EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia. PMID:26083390
ImmuSort, a database on gene plasticity and electronic sorting for immune cells. PMID:25988315
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms. PMID:25849990
Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia. PMID:25822018
The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia. PMID:25789315
The subtype-specific features of EVI1 and PRDM16 in acute myeloid leukemia. PMID:25740107
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia. PMID:25349154
ImmuCo: a database of gene co-expression in immune cells. PMID:25326331
A therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia. PMID:25186176
CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia. PMID:25184385
Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML. PMID:24932908
C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors. PMID:24415956
C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner. PMID:24404186 -
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis
PubMed citations: 23.
23 articles citing: HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation : In memoriam Professor Niels Borregaard. PMID:35739121
Leukemic progenitor cells enable immunosuppression and post-chemotherapy relapse via IL-36-inflammatory monocyte axis. PMID:34623912
FAM122A is required for hematopoietic stem cell function. PMID:33262527
Six1 regulates leukemia stem cell maintenance in acute myeloid leukemia. PMID:31050834
Natural Killer Immunotherapy for Minimal Residual Disease Eradication Following Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia. PMID:31027331
BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles. PMID:30395307
Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia. PMID:28220038
MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis. PMID:27755585
The role of the CCN family of proteins in blood cancers. PMID:27485291
A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis. PMID:27338829
Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling. PMID:26716078
High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. PMID:25840412
Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia. PMID:25822018
Nfix expression critically modulates early B lymphopoiesis and myelopoiesis. PMID:25780920
MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia. PMID:25740828
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. PMID:25479751
ELMO1 is upregulated in AML CD34+ stem/progenitor cells, mediates chemotaxis and predicts poor prognosis in normal karyotype AML. PMID:25360637
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia. PMID:25349154
Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis. PMID:24498346
C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner. PMID:24404186
Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia. PMID:24378360
Genome-scale technology driven advances to research into normal and malignant haematopoiesis. PMID:24278696
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis. PMID:23143109 - http://dx.doi.org/10.1093/nar/gkv1101
Tags:
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More detailed information about this field from each metasource.
blood
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
cancer
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene expression data
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
hematopoiesis
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
messenger rna
metasource: Fairsharing.org
version: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
microarray data and other gene expression databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Tags
More detailed information about this field from each metasource.
blood
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
cancer
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene expression data
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
hematopoiesis
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
messenger rna
metasource: Fairsharing.orgversion: FAIRsharing.org: BloodSpot; BloodSpot; DOI: https://doi.org/10.25504/FAIRsharing.f5xs6m; Last edited: Jan. 8, 2019, 1:15 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
microarray data and other gene expression databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
blood cancer gene gene expression hematopoiesis messenger rna microarray data and other gene expression
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