Machine Learning Techniques for the Prediction of B-Cell and T-Cell Epitopes as Potential Vaccine Targets with a Specific Focus on SARS-CoV-2 Pathogen: A Review.
PMID:35215090
Acid Stripping after Infection Improves the Detection of Viral HLA Class I Natural Ligands Identified by Mass Spectrometry.
PMID:34638844
Molecular insight into the affinity, specificity and cross-reactivity of systematic hepatocellular carcinoma RALT interaction profile with human receptor tyrosine kinases.
PMID:34618235
Prospective Evaluation of Radiotherapy-Induced Immunologic and Genetic Effects in Colorectal Cancer Oligo-Metastatic Patients with Lung-Limited Disease: The PRELUDE-1 Study.
PMID:34439390
T Cell Specificity: A Great Challenge in Chagas Disease.
PMID:34267750
Recent progress on MHC-I epitope prediction in tumor immunotherapy.
PMID:34249407
Predicting MHC class I binder: existing approaches and a novel recurrent neural network solution.
PMID:34131696
Infectious disease mRNA vaccines and a review on epitope prediction for vaccine design.
PMID:34089044
Whole genome deep sequencing analysis of viral quasispecies diversity and evolution in HBeAg seroconverters.
PMID:33870157
Cytotoxic T-lymphocyte elicited vaccine against SARS-CoV-2 employing immunoinformatics framework.
PMID:33828130
Peptide-based therapeutic cancer vaccine: Current trends in clinical application.
PMID:33754407
MHCII3D-Robust Structure Based Prediction of MHC II Binding Peptides.
PMID:33374958
Cytotoxic T-lymphocyte elicited therapeutic vaccine candidate targeting cancer against MAGE-A11 carcinogenic protein.
PMID:33169789
MMP-7 derived peptides with MHC class-I binding motifs from canine mammary tumor tissue elicit strong antigen-specific T-cell responses in BALB/c mice.
PMID:32970284
Point mutation screening of tumor neoantigens and peptide-induced specific cytotoxic T lymphocytes using The Cancer Genome Atlas database.
PMID:32934692
Antigen processing and presentation in cancer immunotherapy.
PMID:32859742
A novel neoantigen discovery approach based on chromatin high order conformation.
PMID:32854726
Vaccine candidate designed against carcinoembryonic antigen-related cell adhesion molecules using immunoinformatics tools.
PMID:32720576
Distinctive germline expression of class I human leukocyte antigen (HLA) alleles and DRB1 heterozygosis predict the outcome of patients with non-small cell lung cancer receiving PD-1/PD-L1 immune checkpoint blockade.
PMID:32554614
Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system.
PMID:32453790
Modulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2).
PMID:32265295
Identification of novel HLA-A0201-restricted T-cell epitopes against thyroid antigens in autoimmune thyroid diseases.
PMID:32198668
Cancer testis antigen Cyclin A1 harbors several HLA-A*02:01-restricted T cell epitopes, which are presented and recognized in vivo.
PMID:32157447
Two unique HLA-A*0201 restricted peptides derived from cyclin E as immunotherapeutic targets in leukemia.
PMID:31908357
Machine Learning for Cancer Immunotherapies Based on Epitope Recognition by T Cell Receptors.
PMID:31798635
Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene.
PMID:31668558
Narrow-Leafed Lupin Main Allergen β-Conglutin (Lup an 1) Detection and Quantification Assessment in Natural and Processed Foods.
PMID:31635336
HLA class I-restricted T cell epitopes isolated and identified from myeloid leukemia cells.
PMID:31575892
Computational approaches for characterizing the tumor immune microenvironment.
PMID:31347163
Generation of IgE-specific cytotoxic T lymphocytes as a novel immunotherapeutic approach for the treatment of allergic asthma.
PMID:31317199
Key Features Relevant to Select Antigens and TCR From the MHC-Mismatched Repertoire to Treat Cancer.
PMID:31316521
MHC-I peptide binding activity assessed by exchange after cleavage of peptide covalently linked to β2-microglobulin.
PMID:31201791
Identification of CD4 and H-2Kd-restricted cytotoxic T lymphocyte epitopes on the human herpesvirus 6B glycoprotein Q1 protein.
PMID:30846739
Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors.
PMID:30835255
Naturally presented HLA class I-restricted epitopes from the neurotrophic factor S100-β are targets of the autoimmune response in type 1 diabetes.
PMID:30817223
Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level.
PMID:30768983
Perspective: The promises of a holistic view of proteins-impact on antibody engineering and drug discovery.
PMID:30630879
Structure-based Methods for Binding Mode and Binding Affinity Prediction for Peptide-MHC Complexes.
PMID:30582480
Association of HLA class I type with prevalence and outcome of patients with acute myeloid leukemia and mutated nucleophosmin.
PMID:30557403
A comprehensive in silico analysis for identification of therapeutic epitopes in HPV16, 18, 31 and 45 oncoproteins.
PMID:30356257
CD8+ Cytotoxic T Lymphocyte Responses and Viral Epitope Escape in Acute HIV-1 Infection.
PMID:30059271
A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules.
PMID:30026743
Quasispecies characters of hepatitis B virus in immunoprophylaxis failure infants.
PMID:29629487
A Targeted LC-MS Strategy for Low-Abundant HLA Class-I-Presented Peptide Detection Identifies Novel Human Papillomavirus T-Cell Epitopes.
PMID:29603667
Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells.
PMID:29541393
Current progress of immunoinformatics approach harnessed for cellular- and antibody-dependent vaccine design.
PMID:29528265
Fundamentals and Methods for T- and B-Cell Epitope Prediction.
PMID:29445754
Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen.
PMID:29434602
In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate.
PMID:29316918
Longevity of antibody and T-cell responses against outer membrane antigens of Orientia tsutsugamushi in scrub typhus patients.
PMID:29259327
Preclinical and clinical development of neoantigen vaccines.
PMID:29253113
Host genotype and time dependent antigen presentation of viral peptides: predictions from theory.
PMID:29084996
Identification of a HLA-A*0201-restricted immunogenic epitope from the universal tumor antigen DEPDC1.
PMID:28919988
Soluble HLA-associated peptide from PSF1 has a cancer vaccine potency.
PMID:28894200
Tools to define the melanoma-associated immunopeptidome.
PMID:28755382
The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition.
PMID:28740497
Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8+ T Cells.
PMID:28634215
NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination.
PMID:28617827
Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks.
PMID:28598281
ImmunoNodes - graphical development of complex immunoinformatics workflows.
PMID:28482806
Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7.
PMID:28389098
Bioinformatic prediction of the epitopes of Echinococcus granulosus antigen 5.
PMID:28357070
The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design.
PMID:28352270
The Human Leukocyte Antigen (HLA)-B27 Peptidome in Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion.
PMID:28188227
Identification of HLA‑A*1101‑restricted cytotoxic T lymphocyte epitopes derived from epidermal growth factor pathway substrate number 8.
PMID:27840923
Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection.
PMID:27717382
Recent advances in T-cell engineering for use in immunotherapy.
PMID:27703664
Immunogenic FEAT protein circulates in the bloodstream of cancer patients.
PMID:27659353
TepiTool: A Pipeline for Computational Prediction of T Cell Epitope Candidates.
PMID:27479659
Personalized cancer vaccines: Targeting the cancer mutanome.
PMID:27449681
Computational genomics tools for dissecting tumour-immune cell interactions.
PMID:27376489
Human T cell responses to Japanese encephalitis virus in health and disease.
PMID:27242166
Designing string-of-beads vaccines with optimal spacers.
PMID:26813686
Genome-Wide Prediction of Vaccine Candidates for Leishmania major: An Integrated Approach.
PMID:26681959
Immunoinformatics and epitope prediction in the age of genomic medicine.
PMID:26589500
Identification of Four-Jointed Box 1 (FJX1)-Specific Peptides for Immunotherapy of Nasopharyngeal Carcinoma.
PMID:26536470
Novel epitopes identified from efflux pumps of Mycobacterium tuberculosis could induce cytotoxic T lymphocyte response.
PMID:26417538
Identification of Conserved Peptides Comprising Multiple T Cell Epitopes of Matrix 1 Protein in H1N1 Influenza Virus.
PMID:26398199
Carfilzomib enhances natural killer cell-mediated lysis of myeloma linked with decreasing expression of HLA class I.
PMID:26323098
Tumor neoantigens: building a framework for personalized cancer immunotherapy.
PMID:26258412
Anti-hepatitis C virus T-cell immunity in the context of multiple exposures to the virus.
PMID:26107956
Accurate prediction of immunogenic T-cell epitopes from epitope sequences using the genetic algorithm-based ensemble learning.
PMID:26020952
Prediction of CD8+ Epitopes in Leishmania braziliensis Proteins Using EPIBOT: In Silico Search and In Vivo Validation.
PMID:25905908
The HIV-1 antisense protein (ASP) induces CD8 T cell responses during chronic infection.
PMID:25809376
Deciphering complex patterns of class-I HLA-peptide cross-reactivity via hierarchical grouping.
PMID:25708537
Immunogenic peptide discovery in cancer genomes.
PMID:25588790
The use of signal peptide domains as vaccine candidates.
PMID:25483491
Immunogenicity of Multi-Epitope DNA and Peptide Vaccine Candidates Based on Core, E2, NS3 and NS5B HCV Epitopes in BALB/c Mice.
PMID:25419219
Uncovering the peptide-binding specificities of HLA-C: a general strategy to determine the specificity of any MHC class I molecule.
PMID:25311805
A common minimal motif for the ligands of HLA-B*27 class I molecules.
PMID:25268942
Soluble HLA technology as a strategy to evaluate the impact of HLA mismatches.
PMID:25254222
Identification and characterization of a cytotoxic T-lymphocyte agonist epitope of brachyury, a transcription factor involved in epithelial to mesenchymal transition and metastasis.
PMID:25186612
Engineering venom's toxin-neutralizing antibody fragments and its therapeutic potential.
PMID:25153256
A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets.
PMID:24970476
Specific targeting of a naturally presented osteosarcoma antigen, papillomavirus binding factor peptide, using an artificial monoclonal antibody.
PMID:24962571
Predicting alloreactivity in transplantation.
PMID:24868561
Hepatitis B splice-generated protein antibodies in Syrian chronic hepatitis B patients: incidence and significance.
PMID:24829585
Can we predict mutant neoepitopes in human cancers for patient-specific vaccine therapy?
PMID:24795140
In vivo immunogenicity of Tax(11-19) epitope in HLA-A2/DTR transgenic mice: implication for dendritic cell-based anti-HTLV-1 vaccine.
PMID:24739247
Integrative immunoinformatics for Mycobacterial diseases in R platform.
PMID:24592289
The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8⁺ T cell responses.
PMID:24503065
DNA vaccines encoding altered peptide ligands for SSX2 enhance epitope-specific CD8+ T-cell immune responses.
PMID:24492013
Results of a randomized phase I gene therapy clinical trial of nononcolytic fowlpox viruses encoding T cell costimulatory molecules.
PMID:24484178
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy.
PMID:24457417
LAPTM4B-35 protein is a weak tumor-associated antigen candidate.
PMID:24396432
A guide to bioinformatics for immunologists.
PMID:24363654
Identification and characterization of agonist epitopes of the MUC1-C oncoprotein.
PMID:24233342
Cancer genome sequencing and its implications for personalized cancer vaccines.
PMID:24213133
Properties of MHC class I presented peptides that enhance immunogenicity.
PMID:24204222
HLA class I alleles are associated with peptide-binding repertoires of different size, affinity, and immunogenicity.
PMID:24190657
Sequence analysis of T-cell repertoires in health and disease.
PMID:24172704
HPV16 E5 peptide vaccine in treatment of cervical cancer in vitro and in vivo.
PMID:24142729
Advances in the study of HLA-restricted epitope vaccines.
PMID:23955319
NetMHCstab - predicting stability of peptide-MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery.
PMID:23927693
An analogue peptide from the Cancer/Testis antigen PASD1 induces CD8+ T cell responses against naturally processed peptide.
PMID:23882161
Peptide-based vaccinology: experimental and computational approaches to target hypervariable viruses through the fine characterization of protective epitopes recognized by monoclonal antibodies and the identification of T-cell-activating peptides.
PMID:23878584
Active vaccination with vaccinia virus A33 protects mice against lethal vaccinia and ectromelia viruses but not against cowpoxvirus; elucidation of the specific adaptive immune response.
PMID:23842430
Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE.
PMID:23750208
Molecular epidemiology and phylodynamics of the human respiratory syncytial virus fusion protein in northern Taiwan.
PMID:23734183
Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.
PMID:23690473
A combination of epitope prediction and molecular docking allows for good identification of MHC class I restricted T-cell epitopes.
PMID:23666426
Prime/boost immunization with DNA and adenoviral vectors protects from hepatitis D virus (HDV) infection after simultaneous infection with HDV and woodchuck hepatitis virus.
PMID:23637419
Antigen-stimulated CD4 T cell expansion can be limited by their grazing of peptide-MHC complexes.
PMID:23606541
Natural HLA-B*2705 protein ligands with glutamine as anchor motif: implications for HLA-B27 association with spondyloarthropathy.
PMID:23430249
Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture.
PMID:23392640
Prediction of MHC class I binding peptides by a query learning algorithm based on hidden markov models.
PMID:23345768
Fowlpox-based survivin vaccination for malignant mesothelioma therapy.
PMID:23335100
T-cell epitope vaccine design by immunoinformatics.
PMID:23303307
Characterization of novel multiantigenic vaccine candidates with pan-HLA coverage against Mycobacterium tuberculosis.
PMID:23283639
An efficient T-cell epitope discovery strategy using in silico prediction and the iTopia assay platform.
PMID:23243589
Cell therapy: a safe and efficacious therapeutic treatment for Alzheimer's disease in APP+PS1 mice.
PMID:23226497
EpicCapo: epitope prediction using combined information of amino acid pairwise contact potentials and HLA-peptide contact site information.
PMID:23176036
A rationally engineered anti-HIV peptide fusion inhibitor with greatly reduced immunogenicity.
PMID:23147734
MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response.
PMID:23144892
Cross-allele cytotoxic T lymphocyte responses against 2009 pandemic H1N1 influenza A virus among HLA-A24 and HLA-A3 supertype-positive individuals.
PMID:23015716
Bioinformatics for cancer immunology and immunotherapy.
PMID:22986455
Phase I clinical study of a personalized peptide vaccination available for six different human leukocyte antigen (HLA-A2, -A3, -A11, -A24, -A31 and -A33)-positive patients with advanced cancer.
PMID:22977478
Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-gamma production and bioinformatics prediction.
PMID:22963340
CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity.
PMID:22943201
Nuclear export signal and immunodominant CD8+ T cell epitope in influenza A virus matrix protein 1.
PMID:22923812
Predicting HLA class I non-permissive amino acid residues substitutions.
PMID:22905104
DNA prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model.
PMID:22718818
Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1(+) leukemias.
PMID:22623625
HapMap SNP Scanner: an online program to mine SNPs responsible for cell phenotype.
PMID:22568758
Trypanosoma cruzi adjuvants potentiate T cell-mediated immunity induced by a NY-ESO-1 based antitumor vaccine.
PMID:22567144
In vitro and in vivo identification of a novel cytotoxic T lymphocyte epitope from Rv3425 of Mycobacterium tuberculosis.
PMID:22537173
Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen.
PMID:22529286
Computational prediction and experimental assessment of an HLA-A*0201-restricted cytotoxic T lymphocyte epitope from neutral endopeptidase.
PMID:22492182
GPS-MBA: computational analysis of MHC class II epitopes in type 1 diabetes.
PMID:22479466
Whole genomes of Chandipura virus isolates and comparative analysis with other rhabdoviruses.
PMID:22272333
Discovery of T cell antigens by high-throughput screening of synthetic minigene libraries.
PMID:22253836
Predictions versus high-throughput experiments in T-cell epitope discovery: competition or synergy?
PMID:22149708
Identification of three novel CTL epitopes within nucleocapsid protein of Hantaan virus.
PMID:22111596
POPISK: T-cell reactivity prediction using support vector machines and string kernels.
PMID:22085524
Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease.
PMID:22072755
Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C.
PMID:22057677
Bacteria modulate the CD8+ T cell epitope repertoire of host cytosol-exposed proteins to manipulate the host immune response.
PMID:22022257
A peptide filtering relation quantifies MHC class I peptide optimization.
PMID:22022238
T-cell epitope finding on EPHA2 for further glioma vaccine development: An immunomics study.
PMID:21977079
The origin of proteasome-inhibitor resistant HLA class I peptidomes: a study with HLA-A*68:01.
PMID:21969608
Optimal viral immune surveillance evasion strategies.
PMID:21925527
In silico analysis of six known Leishmania major antigens and in vitro evaluation of specific epitopes eliciting HLA-A2 restricted CD8 T cell response.
PMID:21909442
Vaccines targeting the cancer-testis antigen SSX-2 elicit HLA-A2 epitope-specific cytolytic T cells.
PMID:21904219
Identification of H-2d restricted T cell epitope of foot-and-mouth disease virus structural protein VP1.
PMID:21896206
Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays.
PMID:21854782
High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations.
PMID:21850230
Emerging vaccine informatics.
PMID:21772787
Concurrent detection of circulating minor histocompatibility antigen-specific CD8+ T cells in SCT recipients by combinatorial encoding MHC multimers.
PMID:21731686
Identification of CD8+ cytotoxic T lymphocyte epitopes from porcine reproductive and respiratory syndrome virus matrix protein in BALB/c mice.
PMID:21619712
FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens.
PMID:21496229
Cytolytic T lymphocytes from HLA-B8+ donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus.
PMID:21429247
Expansion of interferon-gamma-producing multifunctional CD4+ T-cells and dysfunctional CD8+ T-cells by glypican-3 peptide library in hepatocellular carcinoma patients.
PMID:21419713
Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells.
PMID:21407224
Comparative analysis of epitope predictions: proposed library of putative vaccine candidates for HIV.
PMID:21383906
CD8+ T cells specific for the androgen receptor are common in patients with prostate cancer and are able to lyse prostate tumor cells.
PMID:21350948
Optimal epitope composition after antigen screening using a live bacterial delivery vector: application to TRP-2.
PMID:21327126
Immune-induced evolutionary selection focused on a single reading frame in overlapping hepatitis B virus proteins.
PMID:21307195
A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.
PMID:21149604
Real time detection of peptide-MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability.
PMID:21130497
State of the art and challenges in sequence based T-cell epitope prediction.
PMID:21067545
Prediction of epitopes using neural network based methods.
PMID:21047511
Real-time, high-throughput measurements of peptide-MHC-I dissociation using a scintillation proximity assay.
PMID:21044632
Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors.
PMID:20981424
Soluble plasma HLA peptidome as a potential source for cancer biomarkers.
PMID:20974924
The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family.
PMID:20934997
MHC-I prediction using a combination of T cell epitopes and MHC-I binding peptides.
PMID:20920507
Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A*2402.
PMID:20843377
The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes.
PMID:20831383
Advances in cellular therapy for the treatment of thyroid cancer.
PMID:20671939
Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers.
PMID:20668079
Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.
PMID:20637863
Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model.
PMID:20619375
Major histocompatibility complex class I binding predictions as a tool in epitope discovery.
PMID:20518827
Induction of Specific CD8 T Cells against Intracellular Bacteria by CD8 T-Cell-Oriented Immunization Approaches.
PMID:20508818
MetaMHC: a meta approach to predict peptides binding to MHC molecules.
PMID:20483919
HLA-F complex without peptide binds to MHC class I protein in the open conformer form.
PMID:20483783
MHC class II epitope predictive algorithms.
PMID:20408898
HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase.
PMID:20140431
Multiple, non-conserved, internal viral ligands naturally presented by HLA-B27 in human respiratory syncytial virus-infected cells.
PMID:20081153
Characterization of an human leucocyte antigen A2-restricted Epstein-Barr virus nuclear antigen-1-derived cytotoxic T-lymphocyte epitope.
PMID:19922423
Construction of HCV-polytope vaccine candidates harbouring immune-enhancer sequences and primary evaluation of their immunogenicity in BALB/c mice.
PMID:19882243
Discovery of naturally processed and HLA-presented class I peptides from vaccinia virus infection using mass spectrometry for vaccine development.
PMID:19822231
Efficient induction of cytotoxic T lymphocytes specific for severe acute respiratory syndrome (SARS)-associated coronavirus by immunization with surface-linked liposomal peptides derived from a non-structural polyprotein 1a.
PMID:19748524
Discovery of common marburgvirus protective epitopes in a BALB/c mouse model.
PMID:19712478
Identification of HLA-A*2402-restricted HCMV immediate early-1 (IE-1) epitopes as targets for CD8+ HCMV-specific cytotoxic T lymphocytes.
PMID:19698161
Presentation of human T cell leukemia virus type 1 (HTLV-1) Tax protein by dendritic cells: the underlying mechanism of HTLV-1-associated neuroinflammatory disease.
PMID:19656902
Development, characterization, and immunotherapeutic use of peptide mimics of the Thomsen-Friedenreich carbohydrate antigen.
PMID:19649208
Analysis of predicted CD8+ T cell epitopes from proteins encoded by the specific RD regions of Mycobacterium tuberculosis for vaccine development and specific diagnosis.
PMID:19609720
A HCMV pp65 polypeptide promotes the expansion of CD4+ and CD8+ T cells across a wide range of HLA specificities.
PMID:19604317
Functional unresponsiveness and replicative senescence of myeloid leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation.
PMID:19602548
FRED--a framework for T-cell epitope detection.
PMID:19578173
Enhanced systemic immune reactivity to a Basal cell carcinoma associated antigen following photodynamic therapy.
PMID:19549769
Prostvac-VF: a vector-based vaccine targeting PSA in prostate cancer.
PMID:19548854
Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma.
PMID:19542363
Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidases.
PMID:19524006
HLA-A*0201-restricted CTL epitope of a novel osteosarcoma antigen, papillomavirus binding factor.
PMID:19523231
New gene expressed in prostate: a potential target for T cell-mediated prostate cancer immunotherapy.
PMID:19495750
Synthetic peptides coupled to the surface of liposomes effectively induce SARS coronavirus-specific cytotoxic T lymphocytes and viral clearance in HLA-A*0201 transgenic mice.
PMID:19490987
Viruses selectively mutate their CD8+ T-cell epitopes--a large-scale immunomic analysis.
PMID:19478014
OptiTope--a web server for the selection of an optimal set of peptides for epitope-based vaccines.
PMID:19420066
Identification of varicella-zoster virus-specific CD8 T cells in patients after T-cell-depleted allogeneic stem cell transplantation.
PMID:19386715
Interaction of Bap31 and MHC class I molecules and their traffic out of the endoplasmic reticulum.
PMID:19342655
CTL activation using the natural low-affinity epitope 222-229 from tyrosinase-related protein 1 leads to tumor rejection.
PMID:19276379
Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection.
PMID:19264627
Prediction of MHC binding peptide using Gibbs motif sampler, weight matrix and artificial neural network.
PMID:19238237
Ranking of binding and nonbinding peptides to MHC class I molecules using inverse folding approach: implications for vaccine design.
PMID:19238199
A mathematical framework for the selection of an optimal set of peptides for epitope-based vaccines.
PMID:19112482
Vaccinia virus-specific CD8(+) T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humans.
PMID:18955096
The specificity and polymorphism of the MHC class I prevents the global adaptation of HIV-1 to the monomorphic proteasome and TAP.
PMID:18949050
Flanking p10 contribution and sequence bias in matrix based epitope prediction: revisiting the assumption of independent binding pockets.
PMID:18925947
Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes.
PMID:18922097
Side-chain conformational space analysis (SCSA): a multi conformation-based QSAR approach for modeling and prediction of protein-peptide binding affinities.
PMID:18841329
MalVac: database of malarial vaccine candidates.
PMID:18811938
HapMap scanning of novel human minor histocompatibility antigens.
PMID:18809759
Improving peptide-MHC class I binding prediction for unbalanced datasets.
PMID:18803836
iSPOT: a web tool for the analysis and recognition of protein domain specificity.
PMID:18629248
EpiToolKit--a web server for computational immunomics.
PMID:18440979
Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research.
PMID:18366636
Identification of HLA-A2 restricted T-cell epitopes within the conserved region of the immunoglobulin G heavy-chain in patients with multiple myeloma.
PMID:18363871
Identification of novel IGRP epitopes targeted in type 1 diabetes patients.
PMID:18358785
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes.
PMID:18315850
Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus.
PMID:18246203
Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries.
PMID:18221540
Identification of an HLA-A*0201-restricted T-cell epitope on the MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis, by MPT51 overlapping peptide screening.
PMID:18212086
Human major histocompatibility complex (MHC) class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides.
PMID:18195006
Magnitude, breadth, and functional profile of T-cell responses during human immunodeficiency virus primary infection with B and BF viral variants.
PMID:18184702
'1-8 interferon inducible gene family': putative colon carcinoma-associated antigens.
PMID:18071348
Modeling the adaptive immune system: predictions and simulations.
PMID:18045832
Robust quantitative modeling of peptide binding affinities for MHC molecules using physical-chemical descriptors.
PMID:18045233
Identification of Lck-derived peptides applicable to anti-cancer vaccine for patients with human leukocyte antigen-A3 supertype alleles.
PMID:18043580
How does HTLV-I persist despite a strong cell-mediated immune response?
PMID:18042431
T cell responses to human endogenous retroviruses in HIV-1 infection.
PMID:17997601
Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction.
PMID:17973982
Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma.
PMID:17947507
Sequence-based human leukocyte antigen-B typing of patients infected with Ebola virus in Uganda in 2000: identification of alleles associated with fatal and nonfatal disease outcomes.
PMID:17940968
NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence.
PMID:17726526
Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations.
PMID:17604453
Epitope mapping of HSV-1 glycoprotein K (gK) reveals a T cell epitope located within the signal domain of gK.
PMID:17499382
Long-term T cell memory to human leucocyte antigen-A2 supertype epitopes in humans vaccinated against smallpox.
PMID:17488297
A hybrid approach for predicting promiscuous MHC class I restricted T cell epitopes.
PMID:17426378
Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools.
PMID:17381846
Control of mesothelin-expressing ovarian cancer using adoptive transfer of mesothelin peptide-specific CD8+ T cells.
PMID:17377599
Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities.
PMID:17371945
Hepatitis B virus splice-generated protein induces T-cell responses in HLA-transgenic mice and hepatitis B virus-infected patients.
PMID:17360751
Telomerase immunity from bench to bedside: round one.
PMID:17324292
Prediction of supertype-specific HLA class I binding peptides using support vector machines.
PMID:17303158
Peptide vaccine given with a Toll-like receptor agonist is effective for the treatment and prevention of spontaneous breast tumors.
PMID:17283170
Prediction of desmoglein-3 peptides reveals multiple shared T-cell epitopes in HLA DR4- and DR6-associated pemphigus vulgaris.
PMID:17254312
Prediction of cellular immune responses against CFTR in patients with cystic fibrosis after gene therapy.
PMID:17218617
Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection.
PMID:17182672
Processing sites are different in the generation of HLA-A2.1-restricted, T cell reactive tumor antigen epitopes and viral epitopes.
PMID:17166407
A modular concept of HLA for comprehensive peptide binding prediction.
PMID:17119951
SVRMHC prediction server for MHC-binding peptides.
PMID:17059589
The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens.
PMID:17024127
Sequence variations of Epstein-Barr virus LMP1 gene in nasal NK/T-cell lymphoma.
PMID:16917737
Anti-idiotype antibody induced cellular immunity in mice transgenic for human carcinoembryonic antigen.
PMID:16895556
Immunoinformatics comes of age.
PMID:16846250
SVMHC: a server for prediction of MHC-binding peptides.
PMID:16844990
MHC-BPS: MHC-binder prediction server for identifying peptides of flexible lengths from sequence-derived physicochemical properties.
PMID:16832638
A community resource benchmarking predictions of peptide binding to MHC-I molecules.
PMID:16789818
Identification of an immunogenic CD8+ T-cell epitope derived from gamma-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia.
PMID:16778141
Poxvirus CD8+ T-cell determinants and cross-reactivity in BALB/c mice.
PMID:16775319
Secondary anchor substitutions in an HLA-A*0201-restricted T-cell epitope derived from Her-2/neu.
PMID:16597462
Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models.
PMID:16579851
Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma.
PMID:16569595
Interplay of cellular and humoral immune responses against BK virus in kidney transplant recipients with polyomavirus nephropathy.
PMID:16537617
Chemo-immunotherapy of colorectal carcinoma: preclinical rationale and clinical experience.
PMID:16502353
Immunological characterizations of the nucleocapsid protein based SARS vaccine candidates.
PMID:16494977
Prediction of MHC class II binding peptides based on an iterative learning model.
PMID:16351712
A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia.
PMID:16322791
Diversity in the acute CD8 T cell response to vaccinia virus in humans.
PMID:16301664
Lassa fever virus peptides predicted by computational analysis induce epitope-specific cytotoxic-T-lymphocyte responses in HLA-A2.1 transgenic mice.
PMID:16210487
Identification of novel human CTL epitopes and their agonist epitopes of mesothelin.
PMID:16144939
The sentinel within: exploiting the immune system for cancer biomarkers.
PMID:16083262
The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer.
PMID:16043716
Identification of two new HLA-A*1101-restricted tax epitopes recognized by cytotoxic T lymphocytes in an adult T-cell leukemia patient after hematopoietic stem cell transplantation.
PMID:16014972
Integrated modeling of the major events in the MHC class I antigen processing pathway.
PMID:15987883
PREDBALB/c: a system for the prediction of peptide binding to H2d molecules, a haplotype of the BALB/c mouse.
PMID:15980450
MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides.
PMID:15980449
Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes.
PMID:15958640
Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method.
PMID:15927070
Automated generation and evaluation of specific MHC binding predictive tools: ARB matrix applications.
PMID:15868141
H-2 Kd-restricted hepatitis B virus-derived epitope whose specific CD8+ T lymphocytes can produce gamma interferon without cytotoxicity.
PMID:15827171
Mycobacterium tuberculosis genome-wide screen exposes multiple CD8 T cell epitopes.
PMID:15762882
Amino acid variation within the fusion protein of respiratory syncytial virus subtype A and B strains during annual epidemics in South Africa.
PMID:15744582
CD8+ immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells.
PMID:15684323
NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses.
PMID:15671442
Prediction of HLA-A2-restricted CTL epitope specific to HCC by SYFPEITHI combined with polynomial method.
PMID:15633217
Identification of a naturally processed cytotoxic CD8 T-cell epitope of coxsackievirus B4, presented by HLA-A2.1 and located in the PEVKEK region of the P2C nonstructural protein.
PMID:15564450
Molecular genetic characterization and subcellular localization of a putative Theileria annulata membrane protein.
PMID:15490238
Peripheral blood T cell responses to keratin peptides that share sequences with streptococcal M proteins are largely restricted to skin-homing CD8(+) T cells.
PMID:15373909
Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles.
PMID:15349703
Comparative immunopeptidomics of humans and their pathogens.
PMID:15326311
Discriminating self from nonself with short peptides from large proteomes.
PMID:15322777
Modeling the structure of bound peptide ligands to major histocompatibility complex.
PMID:15322290
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients.
PMID:15289501
Development of a DNA vaccine targeting human papillomavirus type 16 oncoprotein E6.
PMID:15280455
Expression of cancer-testis antigens in hepatocellular carcinoma.
PMID:15237429
MAGE-A8 overexpression in transitional cell carcinoma of the bladder: identification of two tumour-associated antigen peptides.
PMID:15213716
Identification of murine H2-Dd- and H2-Ab-restricted T-cell epitopes on a novel protective antigen, MPT51, of Mycobacterium tuberculosis.
PMID:15213124
Identification of parathyroid hormone-related protein-derived peptides immunogenic in human histocompatibility leukocyte antigen-A24+ prostate cancer patients.
PMID:15199397
Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses.
PMID:15194781
Autologous lymphoma vaccines induce human T cell responses against multiple, unique epitopes.
PMID:15146248
Two Salmonella OmpC K(b)-restricted epitopes for CD8+-T-cell recognition.
PMID:15102821
Identification of an HLA-A*0201-restricted CD8+ T-cell epitope SSp-1 of SARS-CoV spike protein.
PMID:15016646
Analysis and prediction of affinity of TAP binding peptides using cascade SVM.
PMID:14978300
High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy.
PMID:14755339
Potential selection of LMP1 variants in nasopharyngeal carcinoma.
PMID:14694118
Proteomics in Vaccinology and Immunobiology: An Informatics Perspective of the Immunone.
PMID:14688414
DNA vaccination protects mice against challenge with Listeria monocytogenes expressing the hepatitis C virus NS3 protein.
PMID:14573658
MHCPred: A server for quantitative prediction of peptide-MHC binding.
PMID:12824380
Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.
PMID:12815107
Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains.
PMID:12805430
Identification of a polymorphic gene, BCL2A1, encoding two novel hematopoietic lineage-specific minor histocompatibility antigens.
PMID:12771180
Large-scale analysis of HLA peptides presented by HLA-Cw4.
PMID:12750860
Reliable prediction of T-cell epitopes using neural networks with novel sequence representations.
PMID:12717023
Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers.
PMID:12692225
Quantitation of CD8+ T cell responses to newly identified HLA-A*0201-restricted T cell epitopes conserved among vaccinia and variola (smallpox) viruses.
PMID:12668642
Kaposi's sarcoma-associated herpesvirus cytotoxic T lymphocytes recognize and target Darwinian positively selected autologous K1 epitopes.
PMID:12634388
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction.
PMID:12626761
A comparative molecular similarity index analysis (CoMSIA) study identifies an HLA-A2 binding supermotif.
PMID:12602948
Multiepitope CD8(+) T cell response to a NY-ESO-1 peptide vaccine results in imprecise tumor targeting.
PMID:12488431
Getting peptide vaccines to work: just a matter of quality control?
PMID:12488425
Recovery of known T-cell epitopes by computational scanning of a viral genome.
PMID:12400854
Vaccination with minigenes encoding V(H)-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus.
PMID:12235207
Detection of peptide-specific CTL-precursors in peripheral blood lymphocytes of cancer patients.
PMID:12232766
Prediction of MHC class I binding peptides, using SVMHC.
PMID:12225620
Expression of cutaneous lymphocyte-associated antigen by CD8(+) T cells specific for a skin-tropic virus.
PMID:12189248
CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients.
PMID:12186971
Rational design of peptide-based tumor vaccines.
PMID:12180543
Identification of cytotoxic T lymphocyte epitopes of human herpesvirus 8.
PMID:12100728
Role of signal sequence in vaccine-induced protection against experimental coccidioidomycosis.
PMID:12065493
Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-Infected patients receiving highly active antiretroviral therapy.
PMID:11861829
Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes.
PMID:11836437
HLA-B*35-restricted CD8(+)-T-cell epitope in Mycobacterium tuberculosis Rv2903c.
PMID:11796635
Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells.
PMID:11781370
Rapid determination of HLA B*07 ligands from the West Nile virus NY99 genome.
PMID:11585536
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy.
PMID:11514604
Identification of the immunodominant H-2K(k)-restricted cytotoxic T-cell epitope in the Borna disease virus nucleoprotein.
PMID:11507203
Predicting sequences and structures of MHC-binding peptides: a computational combinatorial approach.
PMID:11495228
Identification of cyclophilin B-derived peptides capable of inducing histocompatibility leukocyte antigen-A2-restricted and tumor-specific cytotoxic T lymphocytes.
PMID:11473727
A geometric and algebraic view of MHC-peptide complexes and their binding properties.
PMID:11472639
Protection from Ebola virus mediated by cytotoxic T lymphocytes specific for the viral nucleoprotein.
PMID:11222689
Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.
PMID:11136822
Structure-based prediction of binding peptides to MHC class I molecules: application to a broad range of MHC alleles.
PMID:11045629
Immunogenicity of mutations induced by nucleoside reverse transcriptase inhibitors for human immunodeficiency virus type 1-specific cytotoxic T cells.
PMID:10982378
Cytotoxic T cell immunity against telomerase reverse transcriptase in humans.
PMID:10759561
Cytotoxic T-cell-mediated response against Yersinia pseudotuberculosis in HLA-B27 transgenic rat.
PMID:10417137
Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an in vitro melanoma model.
PMID:10048982
Induction of tumor antigen-specific immunity in vivo by a novel vaccinia vector encoding safety-modified simian virus 40 T antigen.
PMID:9923859
Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions.
PMID:9739058
gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand.
PMID:9670040
Identification of a cytotoxic T-lymphocyte response to the novel BARF0 protein of Epstein-Barr virus: a critical role for antigen expression.
PMID:9658107
Antigen processing by proteasomes: insights into the molecular basis of crypticity.
PMID:9228283
Binding of nonamer peptides to three HLA-B51 molecules which differ by a single amino acid substitution in the A-pocket.
PMID:9110930
The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4.
PMID:8642295
Specificity of the H-2 L(d)-restricted cytotoxic T-lymphocyte response to the mouse hepatitis virus nucleocapsid protein.
PMID:8627807
MHC ligands and peptide motifs: first listing.
PMID:7890324
Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen.
PMID:7846047
H-2M3a violates the paradigm for major histocompatibility complex class I peptide binding.
PMID:7722457
Identification of HIV protein-derived cytotoxic T lymphocyte (CTL) epitopes for their possible use as synthetic vaccine.
PMID:7621579
Peptide binding to MHC class I molecules: implications for antigenic peptide prediction.
PMID:7561340
Amino-terminal alteration of the HLA-A*0201-restricted human immunodeficiency virus pol peptide increases complex stability and in vitro immunogenicity.
PMID:7545295
Decrypting the structure of major histocompatibility complex class I-restricted cytotoxic T lymphocyte epitopes with complex peptide libraries.
PMID:7539039
Functional analysis of amino acid residues encompassing and surrounding two neighboring H-2Db-restricted cytotoxic T-lymphocyte epitopes in simian virus 40 tumor antigen.
PMID:7535867
Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides.
PMID:7526383
Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues.
PMID:7523572
The essence of epitopes.
PMID:7523566