abYsis
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abYsis is a web-based antibody research system that includes an integrated database of antibody sequence and structure data. The publicly available version includes pre-analyzed sequence data from the European Molecular Biology Laboratory European Nucleotide Archive (EMBL-ENA) and Kabat as well as structure data from the Protein Data Bank.
Description
More detailed information about this field from each metasource.
abYsis is a web-based antibody research system that includes an integrated database of antibody sequence and structure data. The publicly available version includes pre-analyzed sequence data from the European Molecular Biology Laboratory European Nucleotide Archive (EMBL-ENA) and Kabat as well as structure data from the Protein Data Bank.
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
Webpage:
www.bioinf.org.uk/abysisWebpage
More detailed information about this field from each metasource.
www.bioinf.org.uk/abysis
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
Licence:
Name: abYsis - specific.Licence name
More detailed information about this field from each metasource.Licence URL
More detailed information about this field from each metasource.
http://www.bioinf.org.uk/abysis
metasource: BiŌkeanós-Medsourcingversion: 0.0.1:2022-11-04T13:34:25.975929
Publications:
Publications
More detailed information about this field from each metasource.
abYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction
PMID: 27561707
metasource: BiŌkeanós-Medsourcing
version: 0.0.1:2022-11-04T13:34:25.975929
Publications
More detailed information about this field from each metasource.
abYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction
PMID: 27561707
metasource: BiŌkeanós-Medsourcing
version: 0.0.1:2022-11-04T13:34:25.975929
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abYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction
PubMed citations: 53.
53 articles citing: abYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction
Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis. PMID:35330114
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies. PMID:35293269
The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. PMID:35172158
Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics. PMID:35104168
Structural and functional characterization of a monoclonal antibody blocking TIGIT. PMID:35090381
The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. PMID:34852239
Characterization of Single-Chain Fv Fragments of Neutralizing Antibodies to Rabies Virus Glycoprotein. PMID:34835117
Individualized VDJ recombination predisposes the available Ig sequence space. PMID:34815307
Human plasma IgG1 repertoires are simple, unique, and dynamic. PMID:34613904
RAPID: A Rep-Seq Dataset Analysis Platform With an Integrated Antibody Database. PMID:34484220
Llamanade : an open-source computational pipeline for robust nanobody humanization. PMID:34373858
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. PMID:34019795
IsAb: a computational protocol for antibody design. PMID:33876197
The VH framework region 1 as a target of efficient mutagenesis for generating a variety of affinity-matured scFv mutants. PMID:33859250
Robustification of RosettaAntibody and Rosetta SnugDock. PMID:33764990
Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity. PMID:33675750
Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy. PMID:33647772
Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains. PMID:33508322
Engineering of Humanized Antibodies Against Human Interleukin 5 Receptor Alpha Subunit That Cause Potent Antibody-Dependent Cell-Mediated Cytotoxicity. PMID:33488590
A proteomics-based method for identifying antigens within immune complexes. PMID:33362259
In Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform. PMID:32546687
Physicochemical Rules for Identifying Monoclonal Antibodies with Drug-like Specificity. PMID:32453957
How repertoire data are changing antibody science. PMID:32409582
ASAP-SML: An antibody sequence analysis pipeline using statistical testing and machine learning. PMID:32339164
Ion Binding Properties of a Naturally Occurring Metalloantibody. PMID:32316193
Computational Design of an Allosteric Antibody Switch by Deletion and Rescue of a Complex Structural Constellation. PMID:32232139
An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein. PMID:32125272
Role of a noncanonical disulfide bond in the stability, affinity, and flexibility of a VHH specific for the Listeria virulence factor InlB. PMID:31981247
Development of therapeutic antibodies for the treatment of diseases. PMID:31894001
Electrostatic interactions modulate the differential aggregation propensities of IgG1 and IgG4P antibodies and inform charged residue substitutions for improved developability. PMID:31868219
Photobodies: Light-Activatable Single-Domain Antibody Fragments. PMID:31755215
Computational approaches to therapeutic antibody design: established methods and emerging trends. PMID:31626279
Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics. PMID:31544852
Adaption of human antibody λ and κ light chain architectures to CDR repertoires. PMID:31535139
The ABCD database: a repository for chemically defined antibodies. PMID:31410491
Yvis: antibody high-density alignment visualization and analysis platform with an integrated database. PMID:31106372
AbRSA: A robust tool for antibody numbering. PMID:31020723
Protein engineering approaches for antibody fragments: directed evolution and rational design approaches. PMID:30930630
Nature-inspired design and evolution of anti-amyloid antibodies. PMID:30918024
Selecting and engineering monoclonal antibodies with drug-like specificity. PMID:30822699
Structural characterization of monoclonal antibodies targeting C-terminal Ser404 region of phosphorylated tau protein. PMID:30794086
Antibody-mediated biorecognition of myelin oligodendrocyte glycoprotein: computational evidence of demyelination-related epitopes. PMID:30765742
Understanding and overcoming trade-offs between antibody affinity, specificity, stability and solubility. PMID:30666176
SCALOP: sequence-based antibody canonical loop structure annotation. PMID:30321295
Lessons learned from merging wet lab experiments with molecular simulation to improve mAb humanization. PMID:29757445
AbDb: antibody structure database-a database of PDB-derived antibody structures. PMID:29718130
Modulating Antibody Structure and Function through Directed Mutations and Chemical Rescue. PMID:29609459
Comparative analysis of nanobody sequence and structure data. PMID:29569425
How B-Cell Receptor Repertoire Sequencing Can Be Enriched with Structural Antibody Data. PMID:29276518
Facile Affinity Maturation of Antibody Variable Domains Using Natural Diversity Mutagenesis. PMID:28928732
Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization. PMID:28630325
Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. PMID:28548638
Guiding bispecific monovalent antibody formation through proteolysis of IgG1 single-chain. PMID:28055299
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