WGE
A CRISPR database for genome engineering.
Description
More detailed information about this field from each metasource.
A CRISPR database for genome engineering.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:33:42.209486
Webpage:
http://www.sanger.ac.uk/htgt/wge/Webpage
More detailed information about this field from each metasource.
http://www.sanger.ac.uk/htgt/wge/
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:33:42.209486
Publications:
Publications
More detailed information about this field from each metasource.
WGE: a CRISPR database for genome engineering
PMID: 25979474
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:42.209486
Publications
More detailed information about this field from each metasource.
WGE: a CRISPR database for genome engineering
PMID: 25979474
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:42.209486
-
WGE: a CRISPR database for genome engineering
PubMed citations: 79.
79 articles citing: WGE: a CRISPR database for genome engineering
Principles and Applications of CRISPR Toolkit in Virus Manipulation, Diagnosis, and Virus-Host Interactions. PMID:35326449
The Platelet Collagen Receptor GPVI Is Cleaved by Tspan15/ADAM10 and Tspan33/ADAM10 Molecular Scissors. PMID:35269584
Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis. PMID:34971436
A single-nucleotide mutation within the TBX3 enhancer increased body size in Chinese horses. PMID:34906355
Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for Saturation Genome Editing and other Deep Mutational Scanning experiments. PMID:34791067
HES1 protein oscillations are necessary for neural stem cells to exit from quiescence. PMID:34703994
AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway. PMID:34590152
A Positively Selected MAGEE2 LoF Allele Is Associated with Sexual Dimorphism in Human Brain Size and Shows Similar Phenotypes in Magee2 Null Mice. PMID:34464968
Expression of RUNX1-JAK2 in Human Induced Pluripotent Stem Cell-Derived Hematopoietic Cells Activates the JAK-STAT and MYC Pathways. PMID:34299194
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage. PMID:34164627
Combinatorial CRISPR screen identifies fitness effects of gene paralogues. PMID:33637726
The Rab32/BLOC-3-dependent pathway mediates host defense against different pathogens in human macrophages. PMID:33523895
Minimal genome-wide human CRISPR-Cas9 library. PMID:33478580
Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools. PMID:33444739
NRL-/- gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors. PMID:33400844
LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation. PMID:33216713
Benchmarking and integrating genome-wide CRISPR off-target detection and prediction. PMID:33137817
Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism. PMID:32989157
Dynamic High-Sensitivity Quantitation of Procollagen-I by Endogenous CRISPR-Cas9 NanoLuciferase Tagging. PMID:32927811
Futuristic CRISPR-based biosensing in the cloud and internet of things era: an overview. PMID:32837247
CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs. PMID:32807781
Tumors induce de novo steroid biosynthesis in T cells to evade immunity. PMID:32680985
A global Slc7a7 knockout mouse model demonstrates characteristic phenotypes of human lysinuric protein intolerance. PMID:32504080
Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription. PMID:32492392
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits. PMID:32400009
Amyloid precursor protein processing in human neurons with an allelic series of the PSEN1 intron 4 deletion mutation and total presenilin-1 knockout. PMID:32395715
The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex. PMID:32111735
Mutational signatures: experimental design and analytical framework. PMID:32059681
Targeting specificity of APOBEC-based cytosine base editor in human iPSCs determined by whole genome sequencing. PMID:31767844
The technical risks of human gene editing. PMID:31696232
WheatCRISPR: a web-based guide RNA design tool for CRISPR/Cas9-mediated genome editing in wheat. PMID:31694550
A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability. PMID:31627256
Human ATG4 autophagy proteases counteract attachment of ubiquitin-like LC3/GABARAP proteins to other cellular proteins. PMID:31315929
Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (I K,ACh). PMID:31208990
A Novel Reporter Mouse Uncovers Endogenous Brn3b Expression. PMID:31197108
Microhomologies are prevalent at Cas9-induced larger deletions. PMID:31127293
Identification of ADAM12 as a Novel Basigin Sheddase. PMID:31013576
Identification of a Functional Non-coding Variant in the GABA A Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research. PMID:30984232
A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor. PMID:30972628
Gene editing enables T-cell engineering to redirect antigen specificity for potent tumor rejection. PMID:30877233
Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice. PMID:30794724
Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. PMID:30773277
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells. PMID:30661429
Crisflash: open-source software to generate CRISPR guide RNAs against genomes annotated with individual variation. PMID:30649181
Gene-edited CRISPy Critters for alcohol research. PMID:30621855
A novel form of JARID2 is required for differentiation in lineage-committed cells. PMID:30573669
Off- and on-target effects of genome editing in mouse embryos. PMID:30518723
Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition. PMID:30375388
Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci. PMID:30275530
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis. PMID:30228258
In vivo CRISPR editing with no detectable genome-wide off-target mutations. PMID:30209390
USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation. PMID:30206189
Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants. PMID:29925374
Applications of CRISPR/Cas System to Bacterial Metabolic Engineering. PMID:29621180
The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation. PMID:29430990
CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells. PMID:29364519
CRISPR Genome Engineering for Human Pluripotent Stem Cell Research. PMID:29158838
CRISPy-web: An online resource to design sgRNAs for CRISPR applications. PMID:29062934
pgRNAFinder: a web-based tool to design distance independent paired-gRNA. PMID:28961776
Thiol-linked alkylation of RNA to assess expression dynamics. PMID:28945705
USH2A Gene Editing Using the CRISPR System. PMID:28918053
Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries. PMID:28785007
The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia. PMID:28710093
Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries. PMID:28533524
CRISPR/Cas9-mediated deletion of lncRNA Gm26878 in the distant Foxf1 enhancer region. PMID:28405742
CRISPRtools: a flexible computational platform for performing CRISPR/Cas9 experiments in the mouse. PMID:28280930
Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion. PMID:28253259
Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis. PMID:28207001
Ensembl 2017. PMID:27899575
GenomeCRISPR - a database for high-throughput CRISPR/Cas9 screens. PMID:27789686
CRISPR-Cas9 enables conditional mutagenesis of challenging loci. PMID:27580957
Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem Cells. PMID:27532820
The 14th Ile residue is essential for Leptin function in regulating energy homeostasis in rat. PMID:27378381
Treating hemoglobinopathies using gene-correction approaches: promises and challenges. PMID:27314256
Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9. PMID:27153724
Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish. PMID:27009152
Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair. PMID:26876963
Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing. PMID:26750397
A new age in functional genomics using CRISPR/Cas9 in arrayed library screening. PMID:26442115
Tags:
Tags
More detailed information about this field from each metasource.
molecular genetics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:42.209486
genomics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:42.209486
dna
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:42.209486
Tags
More detailed information about this field from each metasource.
molecular genetics
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:33:42.209486
genomics
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:33:42.209486
dna
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:33:42.209486
molecular genetics genomics dna
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