CRAM

CRAM is a sequencing read file format that is highly space efficient by using reference-based compression of sequence data and offers both lossless and lossy modes of compression. Building on early proof-of-principle for reference-based compression (Hsi-Yang Fritz, et al. (2011). Genome Res. 21:734-740), the CRAM format balances usability with compression efficiency.

Webpage:
https://www.sanger.ac.uk/science/tools/cram

Publications:

Tags:

dna sequences high throughput screening next generation dna sequencing rna sequence

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