Cancer data are presented for either the patient level cancer diagnosis or “disease type” or the tumour specific sample details of participants in the Cancer arm of the 100,000 Genomes Project. Data Relating to Cancer Participants: cancer_participant_disease For each cancer participant in the 100,000 Genomes Project, this table includes data about their cancer disease type and subtype. cancer_participant_tumour For each cancer participant’s tumour in the 100,000 Genomes Project, this table contains data that characterises the tumour, e.g. staging and grading; morphology and location; recurrence at time of enrolment; and the basis of diagnosis. cancer_participant_tumour_ metastatic_site For each cancer participant in the 100,000 Genomes Project, this table contains the site of their metastatic disease in the body (if applicable) at diagnosis. cancer_care_plan For a proportion of cancer participants in the 100,000 Genomes Project, this table contains information from their NHS cancer care plan on their treatment and care intent, in particular outcomes of MDT meetings and coded connected data (e.g. diagnoses from scans). cancer_surgery For a proportion of cancer participants in the 100,000 Genomes Project, this table contains details of what surgical procedures were had, as well as the specific location of the intervention. cancer_risk_factor_general For a proportion of cancer participants in the 100,000 Genomes Project, this table contains data on general cancer risk factors, namely smoking status, height, weight and alcohol consumption. This table was compiled with input from GeCIP members. cancer_risk_factor_cancer_specific: For a proportion of cancer participants in the 100,000 Genomes Project, this table contains data on specific risk factors related to particular cancer types. This table was compiled with input from GeCIP members. cancer_invest_imaging: For a proportion of cancer participants in the 100,000 Genomes Project, this table contains: coded data on imaging investigations characterising the scan, its modality, anatomical site and outcome; as well as the outcome of the imaging report in free text form. Data derived from or relating to tumour samples: cancer_invest_sample_pathology: For a proportion of cancer participants in the 100,000 Genomes Project, this table contains full pathology reports and other related data on and from their tumour samples around diagnosis and characterisation of the cancer. Please note that much of this information is also found in the clinic_sample and cancer_participant_tumour tables. cancer_specific_pathology: For a proportion tumours from cancer participants in the 100,000 Genomes Project, this table contains pathology data specific to that participant’s cancer type. This may provide additional data to the cancer_invest_sample_pathology and cancer_participant_tumour tables. cancer_systemic_anti_cancer_therapy: For a proportion tumours from cancer participants in the 100,000 Genomes Project, this table contains details the regimen and intent of the patients’ chemotherapy. cancer_invest_circulating_tumour_marker: For a proportion tumours from cancer participants in the 100,000 Genomes Project, this table contains biomarker measurements specific to particular cancer types.
cancer genomics genome england dna sequencing data data-can