Structure, function, and evolution of plant ADP-glucose pyrophosphorylase.
PMID:35006475
A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus.
PMID:34710357
Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance.
PMID:34663447
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR.
PMID:34530905
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.
PMID:34493871
Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3.
PMID:34155196
A comprehensive survey of regulatory network inference methods using single cell RNA sequencing data.
PMID:34020546
Sex-specific DNA methylation differences in Alzheimer's disease pathology.
PMID:33902726
A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cells.
PMID:33712417
Insights into the genomic repertoire of Aquimarina litoralis CCMR20, a symbiont of coral Mussismilia braziliensis.
PMID:33675372
Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia.
PMID:33649198
Identification and Characterisation of Putative Enhancer Elements in Mouse Embryonic Stem Cells.
PMID:33623376
Metabolic control of DNA methylation in naive pluripotent cells.
PMID:33526924
Systematic clustering algorithm for chromatin accessibility data and its application to hematopoietic cells.
PMID:33253153
Interactions between lineage-associated transcription factors govern haematopoietic progenitor states.
PMID:33103827
Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz.
PMID:32978601
Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder.
PMID:32929078
COCOA: coordinate covariation analysis of epigenetic heterogeneity.
PMID:32894181
Circadian rhythm influences induction of trained immunity by BCG vaccination.
PMID:32692732
The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in human PSCs.
PMID:32398665
An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis.
PMID:32132109
Informatics Approaches for Harmonized Intelligent Integration of Stem Cell Research.
PMID:32099411
Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL.
PMID:31996669
ChIPSummitDB: a ChIP-seq-based database of human transcription factor binding sites and the topological arrangements of the proteins bound to them.
PMID:31942977
A comprehensive resource for retrieving, visualizing, and integrating functional genomics data.
PMID:31818883
Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells.
PMID:31769130
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers.
PMID:31427792
Integrative Approaches to Cancer Immunotherapy.
PMID:31311655
KLF4 protein stability regulated by interaction with pluripotency transcription factors overrides transcriptional control.
PMID:31221664
Risk variants disrupting enhancers of TH1 and TREG cells in type 1 diabetes.
PMID:30910956
LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
PMID:30679800
A common molecular logic determines embryonic stem cell self-renewal and reprogramming.
PMID:30482756
Insights into mammalian transcription control by systematic analysis of ChIP sequencing data.
PMID:30453943
Causal Transcription Regulatory Network Inference Using Enhancer Activity as a Causal Anchor.
PMID:30445760
Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells.
PMID:30033119
LincU Preserves Naïve Pluripotency by Restricting ERK Activity in Embryonic Stem Cells.
PMID:30017820
LOLAweb: a containerized web server for interactive genomic locus overlap enrichment analysis.
PMID:29878235
Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males.
PMID:29804891
KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency.
PMID:29526737
Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition.
PMID:29514091
Dynamics of promoter bivalency and RNAP II pausing in mouse stem and differentiated cells.
PMID:29458328
STAT5BN642H is a driver mutation for T cell neoplasia.
PMID:29200404
StemMapper: a curated gene expression database for stem cell lineage analysis.
PMID:29045725
An extended model for culture-dependent heterogenous gene expression and proliferation dynamics in mouse embryonic stem cells.
PMID:28794899
Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.
PMID:28453575
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.
PMID:28134926
Biological Databases for Hematology Research.
PMID:27965103
Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes.
PMID:27895109
A graphical model approach visualizes regulatory relationships between genome-wide transcription factor binding profiles.
PMID:27780826
Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression Data.
PMID:27551778
Specification of tissue-resident macrophages during organogenesis.
PMID:27492475
Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex.
PMID:27471257
Resolving early mesoderm diversification through single-cell expression profiling.
PMID:27383781
Heat*seq: an interactive web tool for high-throughput sequencing experiment comparison with public data.
PMID:27378302
Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks.
PMID:27346425
Systematic identification of gene family regulators in mouse and human embryonic stem cells.
PMID:27084933
Finding partners to play the music of regulation.
PMID:27034416
Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency.
PMID:26903601
An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability.
PMID:26901438
Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification.
PMID:26675138
SBR-Blood: systems biology repository for hematopoietic cells.
PMID:26590403
CpG island erosion, polycomb occupancy and sequence motif enrichment at bivalent promoters in mammalian embryonic stem cells.
PMID:26582124
LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor.
PMID:26508757
BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis.
PMID:26507857
Epigenetic program and transcription factor circuitry of dendritic cell development.
PMID:26476451
The LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity.
PMID:26161748
Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia.
PMID:26126967
Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility.
PMID:25984238
Web resources for stem cell research.
PMID:25701763
Decoding the regulatory network of early blood development from single-cell gene expression measurements.
PMID:25664528
A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential.
PMID:25512558
Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells.
PMID:25428352