An Integrated In Silico, In Vitro and Tumor Tissues Study Identified Selenoprotein S (SELENOS) and Valosin-Containing Protein (VCP/p97) as Novel Potential Associated Prognostic Biomarkers in Triple Negative Breast Cancer.
PMID:35158912
Lessons learned from SARS-CoV-2 measurements in wastewater.
PMID:34375259
Downregulation of Salivary Proteins, Protective against Dental Caries, in Type 1 Diabetes.
PMID:34287355
Repurposing of Anticancer Stem Cell Drugs in Brain Tumors.
PMID:34165342
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project.
PMID:32939051
Modelling the gene expression and the DNA-binding in the 3T3-L1 differentiating adipocytes.
PMID:31809632
Annot: a Django-based sample, reagent, and experiment metadata tracking system.
PMID:31675914
EdgeScaping: Mapping the spatial distribution of pairwise gene expression intensities.
PMID:31386677
OSCI: standardized stem cell ontology representation and use cases for stem cell investigation.
PMID:31272389
L1000 Viewer: A Search Engine and Web Interface for the LINCS Data Repository.
PMID:31258549
Biomedical Image Processing with Containers and Deep Learning: An Automated Analysis Pipeline: Data architecture, artificial intelligence, automated processing, containerization, and clusters orchestration ease the transition from data acquisition to insights in medium-to-large datasets.
PMID:31094000
Model-Based Clustering With Data Correction For Removing Artifacts In Gene Expression Data.
PMID:30740193
Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
PMID:30210331
A novel method of using Deep Belief Networks and genetic perturbation data to search for yeast signaling pathways.
PMID:30208101
The GCTx format and cmap{Py, R, M, J} packages: resources for optimized storage and integrated traversal of annotated dense matrices.
PMID:30203022
Bioinformatic and biological avenues for understanding alcohol use disorder.
PMID:30144960
Therapeutic Effect of Repurposed Temsirolimus in Lung Adenocarcinoma Model.
PMID:30087612
Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning.
PMID:30034338
Sustainable data and metadata management at the BD2K-LINCS Data Coordination and Integration Center.
PMID:29917015
Saliva Proteomics Analysis Offers Insights on Type 1 Diabetes Pathology in a Pediatric Population.
PMID:29755368
EMUDRA: Ensemble of Multiple Drug Repositioning Approaches to improve prediction accuracy.
PMID:29688306
Drug Repositioning in Glioblastoma: A Pathway Perspective.
PMID:29615902
Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses.
PMID:29322930
The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.
PMID:29199020
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data.
PMID:29140462
Drug target ontology to classify and integrate drug discovery data.
PMID:29122012
PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens.
PMID:28740083
Characterization of transcriptional modules related to fibrosing-NAFLD progression.
PMID:28684781
Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning.
PMID:28208023
The ChEMBL database in 2017.
PMID:27899562
Systematic Quality Control Analysis of LINCS Data.
PMID:27796074
The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability.
PMID:27377652
Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways.
PMID:27364358
RegenBase: a knowledge base of spinal cord injury biology for translational research.
PMID:27055827
Predicting target proteins for drug candidate compounds based on drug-induced gene expression data in a chemical structure-independent manner.
PMID:26684652
Inferring Infection Patterns Based on a Connectivity Map of Host Transcriptional Responses.
PMID:26508266
Metadata management for high content screening in OMERO.
PMID:26476368
Publisher’s Note:Abstraction for data integration:Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction.
PMID:26101093
The Disease Ontology: fostering interoperability between biological and clinical human disease-related data.
PMID:26093607
TIMMA-R: an R package for predicting synergistic multi-targeted drug combinations in cancer cell lines or patient-derived samples.
PMID:25638808
Systematic evaluation of connectivity map for disease indications.
PMID:25606058
Disease Ontology 2015 update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data.
PMID:25348409
Large-scale integration of small molecule-induced genome-wide transcriptional responses, Kinome-wide binding affinities and cell-growth inhibition profiles reveal global trends characterizing systems-level drug action.
PMID:25324859