Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner.
PMID:35902728
Using CRISPR-Cas9 to Dissect Cancer Mutations in Cell Lines.
PMID:35737245
Worldwide Protein Data Bank (wwPDB): A virtual treasure for research in biotechnology.
PMID:34908533
A multi-omic single-cell landscape of human gynecologic malignancies.
PMID:34739872
ATP-binding cassette transporters mediate differential biosynthesis of glycosphingolipid species.
PMID:34597626
Concomitant High Apoptosis Inhibitor of Macrophage (AIM) and Low Prostate-Specific Antigen (PSA) Indicates Activated T Cell-Mediated Anticancer Immunity, Enhance Sensitivity to Pembrolizumab, and Elicit Good Prognosis in Prostate Cancer.
PMID:34572412
DES-Tcell is a knowledgebase for exploring immunology-related literature.
PMID:34253812
Similarities and Differences in Gene Expression Networks Between the Breast Cancer Cell Line Michigan Cancer Foundation-7 and Invasive Human Breast Cancer Tissues.
PMID:34056582
Chloroxine overrides DNA damage tolerance to restore platinum sensitivity in high-grade serous ovarian cancer.
PMID:33854036
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer.
PMID:33822745
Targeting pan-essential genes in cancer: Challenges and opportunities.
PMID:33450197
canSAR: update to the cancer translational research and drug discovery knowledgebase.
PMID:33219674
Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication.
PMID:32966791
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas.
PMID:32727536
Identification of RNA-Binding Proteins as Targetable Putative Oncogenes in Neuroblastoma.
PMID:32707690
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities.
PMID:32433464
Molecular Signatures of Fusion Proteins in Cancer.
PMID:32219217
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
PMID:31959764
PDBe-KB: a community-driven resource for structural and functional annotations.
PMID:31584092
A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.
PMID:31372638
In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR.
PMID:31244651
Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity⁻Brief Review.
PMID:30813234
Leveraging Human Genetics to Guide Cancer Drug Development.
PMID:30652614
canSAR: update to the cancer translational research and drug discovery knowledgebase.
PMID:30496479
ChEMBL: towards direct deposition of bioassay data.
PMID:30398643
Analysis of impact metrics for the Protein Data Bank.
PMID:30325351
Genomics, bio specimens, and other biological data: Current status and future directions.
PMID:30226926
GEMiCCL: mining genotype and expression data of cancer cell lines with elaborate visualization.
PMID:29726944
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
PMID:29662167
Neurofibromin knockdown in glioma cell lines is associated with changes in cytokine and chemokine secretion in vitro.
PMID:29643433
Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells.
PMID:29348601
Objective, Quantitative, Data-Driven Assessment of Chemical Probes.
PMID:29249694
Detection of clinically relevant copy number alterations in oral cancer progression using multiplexed droplet digital PCR.
PMID:28928368
Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer.
PMID:28826504
A simple mathematical approach to the analysis of polypharmacology and polyspecificity data.
PMID:28690829
CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib.
PMID:28566333
Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC).
PMID:28099902
The 24th annual Nucleic Acids Research database issue: a look back and upcoming changes.
PMID:28053160
A comprehensive map of molecular drug targets.
PMID:27910877
The ChEMBL database in 2017.
PMID:27899562
Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening.
PMID:27613601