Collection of samples and data across the following diseases: Fit and well. The QTL (Quantitative Trait Locus) programme is based at the MRC Human Genetics Unit in the University of Edinburgh. The research programme uses the unique population structures in our Scottish and Croatian cohorts to deliver biological understanding of the causes of variation in complex traits. Together, the ORCADES and VIKING biobanks contain 4,000 samples from volunteers with ancestry from the Northern Isles of Scotland, www.ed.ac.uk/viking. Collectively, the CROATIA cohorts contain 6,000 participants. All of these biobanks were constructed from people with high kinship and extensive pedigree structures. They were collected together with detailed phenotype data, some of which is longitudinal. Plasma, serum, urine and DNA samples, as well as detailed genomic, proteomic and metabolomics data can be made available for collaborative research.
qtl programme mrc hgu fit and well quantitative trait locus