Hierarchical Editing Language for Macromolecules
Names
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Hierarchical Editing Language for Macromolecules
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
HELM
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Names
More detailed information about this field from each metasource.
Hierarchical Editing Language for Macromolecules
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
HELM
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Names
More detailed information about this field from each metasource.
Hierarchical Editing Language for Macromolecules
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
HELM
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
HELM (Hierarchical Editing Language for Macromolecules) enables the representation of a wide range of biomolecules (e.g. proteins, nucleotides, antibody drug conjugates) whose size and complexity render existing small-molecule and sequence-based informatics methodologies impractical or unusable. HELM solves this problem through a hierarchical notation that represents complex macromolecules as polymeric structures with support for unnatural components (e.g. unnatural amino acids) and chemical modifications.
Description
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HELM (Hierarchical Editing Language for Macromolecules) enables the representation of a wide range of biomolecules (e.g. proteins, nucleotides, antibody drug conjugates) whose size and complexity render existing small-molecule and sequence-based informatics methodologies impractical or unusable. HELM solves this problem through a hierarchical notation that represents complex macromolecules as polymeric structures with support for unnatural components (e.g. unnatural amino acids) and chemical modifications.
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Webpage:
http://www.OpenHELM.orgWebpage
More detailed information about this field from each metasource.
http://www.OpenHELM.org
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
HELM: a hierarchical notation language for complex biomolecule structure representation
PMID: 22947017
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
HELM Software for Biopolymers
PMID: 28471655
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Publications
More detailed information about this field from each metasource.
HELM: a hierarchical notation language for complex biomolecule structure representation
PMID: 22947017
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
HELM Software for Biopolymers
PMID: 28471655
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
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HELM: a hierarchical notation language for complex biomolecule structure representation
PubMed citations: 13.
13 articles citing: HELM: a hierarchical notation language for complex biomolecule structure representation
Using Machine Learning to Parse Chemical Mixture Descriptions. PMID:34497929
PepFun: Open Source Protocols for Peptide-Related Computational Analysis. PMID:33809815
Proposal of the Annotation of Phosphorylated Amino Acids and Peptides Using Biological and Chemical Codes. PMID:33573096
PFRED: A computational platform for siRNA and antisense oligonucleotides design. PMID:33481821
Molecular representations in AI-driven drug discovery: a review and practical guide. PMID:33431035
Automation and data-driven design of polymer therapeutics. PMID:33242537
Isolating structural errors in reaction networks in systems biology. PMID:32790862
BpForms and BcForms: a toolkit for concretely describing non-canonical polymers and complexes to facilitate global biochemical networks. PMID:32423472
BigSMILES: A Structurally-Based Line Notation for Describing Macromolecules. PMID:31572779
rBAN: retro-biosynthetic analysis of nonribosomal peptides. PMID:30737579
SPICES: a particle-based molecular structure line notation and support library for mesoscopic simulation. PMID:30094683
Annotation of Peptide Structures Using SMILES and Other Chemical Codes-Practical Solutions. PMID:29186902
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. PMID:26464438 -
HELM Software for Biopolymers
PubMed citations: 5.
5 articles citing: HELM Software for Biopolymers
Proposal of the Annotation of Phosphorylated Amino Acids and Peptides Using Biological and Chemical Codes. PMID:33573096
PFRED: A computational platform for siRNA and antisense oligonucleotides design. PMID:33481821
Molecular representations in AI-driven drug discovery: a review and practical guide. PMID:33431035
rBAN: retro-biosynthetic analysis of nonribosomal peptides. PMID:30737579
Annotation of Peptide Structures Using SMILES and Other Chemical Codes-Practical Solutions. PMID:29186902
Tags:
Tags
More detailed information about this field from each metasource.
chemical entity
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
chemical structure
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
molecular entity
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
molecular structure
metasource: Fairsharing.org
version: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
Tags
More detailed information about this field from each metasource.
chemical entity
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
chemical structure
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
molecular entity
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
molecular structure
metasource: Fairsharing.orgversion: FAIRsharing.org: HELM; Hierarchical Editing Language for Macromolecules; DOI: https://doi.org/10.25504/FAIRsharing.pDq8lX; Last edited: Jan. 8, 2019, 1:39 p.m.; Last accessed: Jan 03 2022 7:12 p.m.
chemical entity chemical structure molecular entity molecular structure
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